Cross-linked thymine-purine base tandem lesions: Synthesis, characterization, and measurement in γ-irradiated isolated DNA

Chemical Research in Toxicology

Volumn 15, Issue 4, 2002, Pages 598-606

  Bellon, Sophie ^a   Ravanat, Jean Luc ^a   Gasparutto, Didier ^a   Cadet, Jean ^a  

^a CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 (PHENYLTHIOMETHYL) 2' DEOXYURIDINE; DNA; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; DIAGNOSTIC TEST; DNA DAMAGE; GAMMA IRRADIATION; IONIZING RADIATION; LIQUID CHROMATOGRAPHY; NUCLEOTIDE SEQUENCE; PROTEIN DNA INTERACTION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SENSITIVITY AND SPECIFICITY; SYNTHESIS; TANDEM REPEAT;

ANIMALS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; DNA; DNA ADDUCTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; MASS SPECTROMETRY; PURINES; THYMINE;

EID: 0036229483     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx015594d     Document Type: Article

References (26)

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2. - and OH adducts
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7. Tandem base lesions are generated by hydroxyl radical within isolated DNA in aerated aqueous solution
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