Mutagenicity of oxidized DNA precursors in living cells: Roles of nucleotide pool sanitization and DNA repair enzymes, and translesion synthesis DNA polymerases

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 703, Issue 1, 2010, Pages 32-36

  Kamiya, Hiroyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

2 Hydroxy dATP; 8 Hydroxy dGTP; DNA repair enzyme; Nucleotide pool sanitization enzyme; Oxidized DNA precursor; Translesion synthesis DNA polymerase

Indexed keywords

2 HYDROXY 2' DEOXYGUANOSINE 5' TRIPHOSPHATE; 8 HYDROXY 2' DEOXYGUANOSINE 5' TRIPHOSPHATE; 8 OXO 7,8 DIHYDRO 2' DEOXYGUANOSINE 5' TRIPHOSPHATE; DNA POLYMERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG;

BACTERIAL CELL; DNA DAMAGE; ENZYME SYNTHESIS; MAMMAL CELL; MUTAGENICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE; REVIEW;

ADENOSINE TRIPHOSPHATE; ANIMALS; DEOXYGUANINE NUCLEOTIDES; DEOXYGUANOSINE; DEOXYRIBONUCLEOTIDES; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; HUMANS; MUTAGENS; OXIDATIVE STRESS;

EID: 78549249153     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2010.06.003     Document Type: Review

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