Improved synthesis and mutagenicity of oligonucleotides containing 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine

Chemistry - A European Journal

Volumn 17, Issue 49, 2011, Pages 13782-13788

  Münzel, Martin ^a   Lischke, Ulrike ^a   Stathis, Dimitrios ^a   Pfaffeneder, Toni ^a   Gnerlich, Felix A ^a   Deiml, Christian A ^a   Koch, Sandra C ^a   Karaghiosoff, Konstantin ^a   Carell, Thomas ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

cytosine; DNA; DNA methylation; nucleosides; phosphoramidite

Indexed keywords

CYTOSINE; DNA DEMETHYLATION; DNA METHYLATION; DNA STRANDS; EFFICIENT SYNTHESIS; EPIGENETIC CONTROL; FORMYL GROUP; FUNCTIONALIZATIONS; IN-VITRO; MAMMALIAN DNA; MUTAGENICITY; MUTAGENICITY ASSAY; NUCLEOSIDES; PHOSPHORAMIDITES;

ALKYLATION; BIOMOLECULES; CRYSTAL STRUCTURE; MAMMALS; OLIGONUCLEOTIDES;

DNA;

5 HYDROXYMETHYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DRUG DERIVATIVE; MUTAGENIC AGENT; OLIGONUCLEOTIDE; ORGANOPHOSPHORUS COMPOUND; PHOSPHORAMIDOUS ACID;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DNA METHYLATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SYNTHESIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSINE; DNA METHYLATION; MOLECULAR STRUCTURE; MUTAGENS; OLIGONUCLEOTIDES; ORGANOPHOSPHORUS COMPOUNDS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 82455192844     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201102782     Document Type: Article

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