The case for 8,5′-cyclopurine-2′-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum

Neuroscience

Volumn 145, Issue 4, 2007, Pages 1407-1417

  Brooks, P J ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

cockayne syndrome; DeSanctis Cacchione syndrome; DNA repair; dopamine; Parkinson's disease; transcription

Indexed keywords

8,5' CYCLOPURINE 2' DEOXYNUCLEOSIDE DERIVATIVE; NUCLEOSIDE DERIVATIVE; RNA POLYMERASE II; UNCLASSIFIED DRUG;

AGING; BASAL GANGLION; BRAIN; BRAIN REGION; CLINICAL FEATURE; COCKAYNE SYNDROME; COLONY FORMING UNIT; CORRELATION ANALYSIS; DNA DAMAGE; DNA MODIFICATION; DNA REPAIR; DNA SEQUENCE; EXCISION REPAIR; FOREBRAIN; GENE EXPRESSION; GENE MUTATION; GENETIC DISORDER; GENETIC TRANSCRIPTION; HIPPOCAMPUS; HUMAN; IONIZING RADIATION; KNOCKOUT MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOLOGY; PRIORITY JOURNAL; RADIATION EXPOSURE; REVIEW; ULTRAVIOLET IRRADIATION; WHITE MATTER; XERODERMA PIGMENTOSUM;

COCKAYNE SYNDROME; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; MOLECULAR STRUCTURE; PURINE NUCLEOSIDES; RNA POLYMERASE II; XERODERMA PIGMENTOSUM;

EID: 34247148895     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.10.025     Document Type: Review

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