Radiation-induced formation of a crosslink between base moieties of deoxyguanosine and thymidine in deoxygenated solutions of d(CpGpTpA)

Radiation Research

Volumn 145, Issue 5, 1996, Pages 641-643

  Box, Harold C ^a   Budzinski, Edwin E ^a   Dawidzik, Jean D ^a   Wallace, John C ^a   Evans, Marianne S ^a   Gobey, Jason S ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGUANOSINE; OXYGEN; THYMIDINE;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL REACTION KINETICS; COVALENT BOND; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RADIATION INJURY; RADIOCHEMISTRY; X IRRADIATION;

ACID PHOSPHATASE; ANIMALS; BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; MALE; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHODIESTERASE I; PHOSPHORIC DIESTER HYDROLASES; PROSTATE; THYMIDINE; X-RAYS;

EID: 0029868695     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579285     Document Type: Article

References (12)

1. H. C. Box, H. G. Freund, E. E. Budzinski, J. C. Wallace and A. E. Maccubbin. The differential lysis of phosphoester bonds by nuclease P1. Biochim. Biophys. Acta 1161, 291-294 (1993).
2. C. R. Paul, J. C. Wallace, J. L. Alderfer and H. C. Box. Radiation chemistry of d(TpApCpG) in oxygenated solution. Int. J. Radiat. Biol. 54, 403-415 (1988).
3. K. Keck, Bildung von cyclonucleotiden bei bestrahlung wässriger lösungen von purinnucleotiden. Z. Naturforsch. B 23, 1034-1043 (1968).
4. N. Mariaggi, J. Cadet and R. Teoule, Gamma-radiolytic induced cyclization of 2′ deoxyadenosine in aqueous solution. Tetrahedron 32, 2385-2387(1976).
5. A. F. Fuciareili, G. G. Miller and J. A. Raleigh, An immunochemical probe for 8,5′-cycloadenosine-5'-monophosphate and its deoxy analog in irradiated nucleic acids. Radiat. Res. 104, 272-283 (1985).
6. M-L. Dirksen, W. F. Blakely, H. E. Holwitt and M. Dizdaroglu, Effect of DNA conformation on the hydroxyl radical-induced formation of 8,5′-cyclopurine 2′-deoxyribonucleoside residues in DNA. Int. J. Radiat. Biol. 54, 1504-1510 (1972).
7. M. Dizdaroglu, Free-radical-induced formation of an 8,5′-cyclodeoxyguanosine moiety in deoxyribonucieic acid. Biochem. J. 238, 247-254 (1986).
8. S. Arnott and D. W. L. Hukins, Optimised parameters for A-DNA and B-DNA. Biochem. Biophys. Res. Commun. 47, 1504-1510 (1972).
9. H. C. Box, E. E. Budzinski, H. G. Freund, M. S. Evans, H. B. Patrzyc, J. C. Wallace and A. E. Maccubbin, Vicinal lesions in x-irradiated DNA? Int. J. Radiat. Biol. 64, 261-263 (1993).
10. H. C, Box, H. G. Freund, E. E. Budzinski, J. C. Wallace and A. E. Maccubbin. Free radical-induced double base lesions. Radiat. Res. 141, 91-94 (1995).
11. E. E. Budzinski, A. E. Maccubbin, H. G. Freund, J. C. Wallace and H. C. Box, Characterization of the products of dinucleoside monophosphates d(GpN) irradiated in aqueous solutions. Radiat. Res. 136, 171-177 (1993).
12. E. E. Budzinski, J. D. Dawidzik, J. C. Wallace, H. G. Freund and H. C. Box, The radiation chemistry of d(CpGpTpA) in the presence of oxygen. Radiat. Res. 142, 107-109 (1995).