Being flexible: The voltage-controllable activation gate of Kv channels

Frontiers in Pharmacology

Volumn 3 SEP, Issue , 2012, Pages

  Labro, Alain J ^a   Snyders, Dirk J ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Bundle crossing gate; Glycine and PXP hinge point; Pore opening and closure; Selectivity filter; Shaker potassium channel; Voltage dependent gating

Indexed keywords

CADMIUM; GLYCINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KCNQ1; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCSA; POTASSIUM CHANNEL KIRBAC1.1; POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL KV3.1; POTASSIUM ION; PROLINE; QUATERNARY AMMONIUM DERIVATIVE; SHAKER POTASSIUM CHANNEL; TETRYLAMMONIUM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ALPHA HELIX; AMINO ACID SUBSTITUTION; BUNDLE CROSSING GATE; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; HINGE REGION; HYDROPHOBICITY; INTRACELLULAR TRANSPORT; M2 SEGMENT; POTASSIUM CONDUCTANCE; POTASSIUM TRANSPORT; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STRUCTURE; REVIEW; S1 SEGMENT VOLTAGE SENSING DOMAIN; S2 SEGMENT VOLTAGE SENSING DOMAIN; S3 SEGMENT VOLTAGE SENSING DOMAIN; S4 SEGMENT VOLTAGE SENSING DOMAIN; S4S5 LINKER; S5 PORE DOMAIN; S6C PORE DOMAIN; SELECTIVITY FILTER GATE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS;

EID: 84867135827     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00168     Document Type: Review

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