Tail end of the S6 segment: Role in permeation in Shaker potassium channels

Journal of General Physiology

Volumn 120, Issue 1, 2002, Pages 87-97

  Ding, Shinghua ^a   Horn, Richard ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Nonstationary noise analysis; Pore block; Rubidium; Selectivity

Indexed keywords

ASPARAGINE; CATION; CYSTEINE; MEMBRANE PROTEIN; MUTANT PROTEIN; PHENYLALANINE; POTASSIUM CHANNEL; POTASSIUM ION; PROTEIN SUBUNIT; RUBIDIUM ION; SHAKER POTASSIUM CHANNEL; TETRABUTYLAMMONIUM; THREONINE; TYROSINE; UNCLASSIFIED DRUG; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; RUBIDIUM; TETRYLAMMONIUM;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; CATION TRANSPORT; CHANNEL GATING; CONTROLLED STUDY; CYTOPLASM; DEPOLARIZATION; ELECTRIC POTENTIAL; EMBRYO; ENERGY; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; NOISE; PROTEIN CONFORMATION; BIOLOGICAL MODEL; CELL LINE; DRUG EFFECT; ELECTROPHYSIOLOGY; GENETICS; METABOLISM; MUTATION; PATCH CLAMP; PERMEABILITY; PHYSIOLOGY;

CELL LINE; CYTOPLASM; ELECTROPHYSIOLOGY; HUMAN; MODELS, BIOLOGICAL; MUTATION; PATCH-CLAMP TECHNIQUES; PERMEABILITY; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RUBIDIUM; SUPPORT, U.S. GOV'T, P.H.S.; TETRAETHYLAMMONIUM; HUMANS; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS;

EID: 0036020149     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.20028611     Document Type: Article

References (37)

1. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axons
2. Ion channel selectivity, permeation, and block
3. The voltage sensor in voltage dependent ion channels
4. Fitting and statistical analysis of single-channel records
5. + channel and its structural implications
6. + channel
7. + conduction and selectivity
8. Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels
9. Ionic selectivity revisited: The role of kinetic and equilibrium processes in ion permeation through channels
10. Blockage of squid axon potassium conductance by internal tetra-N-alkylammonium ions of various sizes
11. + channel block by quaternary alkylammonium ions: Dimension and properties of the inner pore
12. + channel
13. + channel signature sequence
14. + channel
15. Nonstationary noise analysis and application to patch clamp recordings
16. Potassium channels as multi-ion single-file pores
17. + channel
18. + channel can be trapped in the open state by an intersubunit metal bridge
19. Conversation between voltage sensors and gates of ion channels
20. Structural features in eukaryotic mRNAs that modulate the initiation of translation
21. + channel
22. + selectivity filter
23. +-channel activation gating
24. Activation gating in KcsA: Structural and functional coupling between elements of the permeation path
25. + channels
26. + channel: Electrostatic stabilization of monovalent cations
27. The variance of sodium current fluctuations at the node of Ranvier
28. Voltage gating of ion channels
29. + fluxes through recombinant Shaker potassium channels expressed in single Xenopus oocytes
30. Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates
31. + and Rb+
32. + ion binding site in Shaker K channels
33. + channels of bovine chromaffin cells
34. The moving parts of voltage-gated ion channels
35. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
36. + channel-Fab complex at 2.0 Å resolution