Stabilizing the closed S6 gate in the shaker Kv channel through modification of a hydrophobic seal

Journal of General Physiology

Volumn 124, Issue 4, 2004, Pages 319-332

  Kitaguchi, Tetsuya ^a   Sukhareva, Manana ^a   Swartz, Kenton J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Agitoxin; Closed gate; Mutagenesis; Potassium channel; Voltage dependent gating

Indexed keywords

PROTEIN S6; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; GENE MUTATION; INTRACELLULAR MEMBRANE; ION CONDUCTANCE; OOCYTE; PHENOTYPE; WILD TYPE;

ANIMALS; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; HYDROPHOBICITY; ION CHANNEL GATING; MEMBRANE POTENTIALS; MUTAGENESIS, SITE-DIRECTED; OOCYTES; POTASSIUM CHANNELS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 5144223114     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409098     Document Type: Article

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