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Volumn , Issue , 2012, Pages

PPARG epigenetic deregulation and its role in colorectal tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRILYSIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROSTAGLANDIN E2; TRASTUZUMAB; UNTRANSLATED RNA;

EID: 84864929802     PISSN: 16874757     EISSN: 16874765     Source Type: Journal    
DOI: 10.1155/2012/687492     Document Type: Review
Times cited : (29)

References (143)
  • 1
    • 0347753697 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors and cancers: Complex stories
    • Michalik L., Desvergne B., Wahli W., Peroxisome-proliferator-activated receptors and cancers: complex stories Nature Reviews Cancer 2004 4 1 61 70 (Pubitemid 38082154)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 61-70
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 2
    • 74049113265 scopus 로고    scopus 로고
    • Nuclear receptors in head and neck cancer: Current knowledge and perspectives
    • Schweitzer A., Knauer S. K., Stauber R. H., Nuclear receptors in head and neck cancer: current knowledge and perspectives International Journal of Cancer 2010 126 4 801 809
    • (2010) International Journal of Cancer , vol.126 , Issue.4 , pp. 801-809
    • Schweitzer, A.1    Knauer, S.K.2    Stauber, R.H.3
  • 3
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPAR
    • Lehrke M., Lazar M. A., The many faces of PPAR Cell 2005 123 6 993 999
    • (2005) Cell , vol.123 , Issue.6 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 4
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I., Green S., Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators Nature 1990 347 6294 645 650
    • (1990) Nature , vol.347 , Issue.6294 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 6
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • DOI 10.1016/0092-8674(95)90200-7
    • Mangelsdorf D. J., Evans R. M., The RXR heterodimers and orphan receptors Cell 1995 83 6 841 850 (Pubitemid 26006526)
    • (1995) Cell , vol.83 , Issue.6 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 8
    • 45249099362 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and progression of colorectal cancer
    • Wang D., DuBois R. N., Peroxisome proliferator-activated receptors and progression of colorectal cancer PPAR Research 2008 2008 7
    • (2008) PPAR Research , vol.2008 , pp. 7
    • Wang, D.1    Dubois, R.N.2
  • 9
    • 48749087487 scopus 로고    scopus 로고
    • Mitochondria, PPARs, and cancer: Is receptor-independent action of PPAR agonists a key?
    • Scatena R., Bottoni P., Giardina B., Mitochondria, PPARs, and cancer: is receptor-independent action of PPAR agonists a key? PPAR Research 2008 2008 10
    • (2008) PPAR Research , vol.2008 , pp. 10
    • Scatena, R.1    Bottoni, P.2    Giardina, B.3
  • 10
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • Desvergne B., Wahli W., Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocrine Reviews 1999 20 5 649 688 (Pubitemid 30650602)
    • (1999) Endocrine Reviews , vol.20 , Issue.5 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 11
    • 0034713444 scopus 로고    scopus 로고
    • Roles of PPARS in health and disease
    • DOI 10.1038/35013000
    • Kersten S., Desvergne B., Wahli W., Roles of PPARS in health and disease Nature 2000 405 6785 421 424 (Pubitemid 30367411)
    • (2000) Nature , vol.405 , Issue.6785 , pp. 421-424
    • Kersten, S.1    Desvergne, B.2    Wahli, W.3
  • 12
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • DOI 10.1210/en.2003-0288
    • Lee C. H., Olson P., Evans R. M., Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors Endocrinology 2003 144 6 2201 2207 (Pubitemid 36629867)
    • (2003) Endocrinology , vol.144 , Issue.6 , pp. 2201-2207
    • Lee, C.-H.1    Olson, P.2    Evans, R.M.3
  • 13
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • DOI 10.1038/nm1025
    • Evans R. M., Barish G. D., Wang Y. X., PPARs and the complex journey to obesity Nature Medicine 2004 10 4 355 361 (Pubitemid 38508511)
    • (2004) Nature Medicine , vol.10 , Issue.4 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.-X.3
  • 14
    • 14844320128 scopus 로고    scopus 로고
    • PPAR trilogy from metabolism to cancer
    • DOI 10.1097/01.mco.0000134360.30911.bb
    • Nahlé Z., PPAR trilogy from metabolism to cancer Current Opinion in Clinical Nutrition and Metabolic Care 2004 7 4 397 402 (Pubitemid 40340645)
    • (2004) Current Opinion in Clinical Nutrition and Metabolic Care , vol.7 , Issue.4 , pp. 397-402
    • Nahle, Z.1
  • 16
    • 33644652740 scopus 로고    scopus 로고
    • Involvement of PPAR nuclear receptors in tissue injury and wound repair
    • DOI 10.1172/JCI27958
    • Michalik L., Wahli W., Involvement of PPAR nuclear receptors in tissue injury and wound repair Journal of Clinical Investigation 2006 116 3 598 606 (Pubitemid 43326864)
    • (2006) Journal of Clinical Investigation , vol.116 , Issue.3 , pp. 598-606
    • Michalik, L.1    Wahli, W.2
  • 18
    • 33744797915 scopus 로고    scopus 로고
    • Peroxisome proliferator - Activated receptor α activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt
    • DOI 10.1158/1078-0432.CCR-05-2556
    • Grabacka M., Plonka P. M., Urbanska K., Reiss K., Peroxisome proliferator-Activated receptor activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt Clinical Cancer Research 2006 12 10 3028 3036 (Pubitemid 43837347)
    • (2006) Clinical Cancer Research , vol.12 , Issue.10 , pp. 3028-3036
    • Grabacka, M.1    Plonka, P.M.2    Urbanska, K.3    Reiss, K.4
  • 19
    • 17044375811 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors
    • Strakova N., Ehrmann J., Bartos J., Malikova J., Dolezel J., Kolar Z., Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors Neoplasma 2005 52 2 126 136
    • (2005) Neoplasma , vol.52 , Issue.2 , pp. 126-136
    • Strakova, N.1    Ehrmann, J.2    Bartos, J.3    Malikova, J.4    Dolezel, J.5    Kolar, Z.6
  • 20
    • 33645562489 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1
    • Grau R., Punzn C., Fresno M., Iiguez M. A., Peroxisome-proliferator- activated receptor agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1 Biochemical Journal 2006 395 1 81 88
    • (2006) Biochemical Journal , vol.395 , Issue.1 , pp. 81-88
    • Grau, R.1    Punzn, C.2    Fresno, M.3    Iiguez, M.A.4
  • 21
    • 2442708845 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-δ attenuates colon carcinogenesis
    • DOI 10.1038/nm1026
    • Harman F. S., Nicol C. J., Marin H. E., Ward J. M., Gonzalez F. J., Peters J. M., Peroxisome proliferator-activated receptor- attenuates colon carcinogenesis Nature Medicine 2004 10 5 481 483 (Pubitemid 38667905)
    • (2004) Nature Medicine , vol.10 , Issue.5 , pp. 481-483
    • Harman, F.S.1    Nicol, C.J.2    Marin, H.E.3    Ward, J.M.4    Gonzalez, F.J.5    Peters, J.M.6
  • 22
    • 10644231009 scopus 로고    scopus 로고
    • PPARδ status and Apc-mediated tumourigenesis in the mouse intestine
    • DOI 10.1038/sj.onc.1208143
    • Reed K. R., Sansom O. J., Hayes A. J., Gescher A. J., Winton D. J., Peters J. M., Clarke A. R., PPAR status and Apc-mediated tumourigenesis in the mouse intestine Oncogene 2004 23 55 8992 8996 (Pubitemid 39657790)
    • (2004) Oncogene , vol.23 , Issue.55 , pp. 8992-8996
    • Reed, K.R.1    Sansom, O.J.2    Hayes, A.J.3    Gescher, A.J.4    Winton, D.J.5    Peters, J.M.6    Clarke, A.R.7
  • 23
    • 2342640982 scopus 로고    scopus 로고
    • Activation of Peroxisome Proliferator-Activated Receptor δ Stimulates the Proliferation of Human Breast and Prostate Cancer Cell Lines
    • DOI 10.1158/0008-5472.CAN-03-2760
    • Stephen R. L., Gustafsson M. C. U., Jarvis M., Tatoud R., Marshall B. R., Knight D., Ehrenborg E., Harris A. L., Wolf C. R., Palmer C. N. A., Activation of peroxisome proliferator-activated receptor stimulates the proliferation of human breast and prostate cancer cell lines Cancer Research 2004 64 9 3162 3170 (Pubitemid 38581418)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3162-3170
    • Stephen, R.L.1    Gustafsson, M.C.U.2    Jarvis, M.3    Tatoud, R.4    Marshall, B.R.5    Knight, D.6    Ehrenborg, E.7    Harris, A.L.8    Wolf, C.R.9    Palmer, C.N.A.10
  • 24
    • 0042388005 scopus 로고    scopus 로고
    • PPARδ activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells
    • DOI 10.1016/S0006-291X(03)01384-6
    • Glinghammar B., Skogsberg J., Hamsten A., Ehrenborg E., PPAR activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells Biochemical and Biophysical Research Communications 2003 308 2 361 368 (Pubitemid 36937188)
    • (2003) Biochemical and Biophysical Research Communications , vol.308 , Issue.2 , pp. 361-368
    • Glinghammar, B.1    Skogsberg, J.2    Hamsten, A.3    Ehrenborg, E.4
  • 25
    • 0032582349 scopus 로고    scopus 로고
    • PPARγ3 mRNA: A distinct PPARγ mRNA subtype transcribed from an independent promoter
    • DOI 10.1016/S0014-5793(98)01273-3, PII S0014579398012733
    • Fajas L., Fruchart J. C., Auwerx J., PPAR 3 mRNA: a distinct PPAR mRNA subtype transcribed from an independent promoter FEBS Letters 1998 438 1-2 55 60 (Pubitemid 28517834)
    • (1998) FEBS Letters , vol.438 , Issue.1-2 , pp. 55-60
    • Fajas, L.1    Fruchart, J.-C.2    Auwerx, J.3
  • 26
    • 8744247436 scopus 로고    scopus 로고
    • A single-base mutation in the peroxisome proliferator-activated receptor γ4 promoter associated with altered in vitro expression and partial lipodystrophy
    • DOI 10.1210/jc.2004-0280
    • Al-Shali K., Cao H., Knoers N., Hermus A. R., Tack C. J., Hegele R. A., A single-base mutation in the peroxisome proliferator-activated receptor 4 promoter associated with altered in vitro expression and partial lipodystrophy Journal of Clinical Endocrinology and Metabolism 2004 89 11 5655 5660 (Pubitemid 39518455)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.11 , pp. 5655-5660
    • Al-Shali, K.1    Cao, H.2    Knoers, N.3    Hermus, A.R.4    Tack, C.J.5    Hegele, R.A.6
  • 27
    • 0027749599 scopus 로고
    • Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
    • Zhu Y., Alvares K., Huang Q., Rao M. S., Reddy J. K., Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver Journal of Biological Chemistry 1993 268 36 26817 26820 (Pubitemid 24006385)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.36 , pp. 26817-26820
    • Zhu, Y.1    Alvares, K.2    Huang, Q.3    Rao, M.S.4    Reddy, J.K.5
  • 28
    • 4744340732 scopus 로고    scopus 로고
    • Impact of genetic variation of PPARγ in humans
    • DOI 10.1016/j.ymgme.2004.08.014, PII S1096719204002239, ASHG 2004 Meeting Toronto
    • Meirhaeghe A., Amouyel P., Impact of genetic variation of PPAR in humans Molecular Genetics and Metabolism 2004 83 1-2 93 102 (Pubitemid 39311284)
    • (2004) Molecular Genetics and Metabolism , vol.83 , Issue.1-2 , pp. 93-102
    • Meirhaeghe, A.1    Amouyel, P.2
  • 30
    • 33744497272 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis
    • DOI 10.1210/me.2006-0025
    • Hummasti S., Tontonoz P., The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis Molecular Endocrinology 2006 20 6 1261 1275 (Pubitemid 43804815)
    • (2006) Molecular Endocrinology , vol.20 , Issue.6 , pp. 1261-1275
    • Hummasti, S.1    Tontonoz, P.2
  • 31
    • 7944236265 scopus 로고    scopus 로고
    • The transactivating function of peroxisome proliferator-activated receptor γ is negatively regulated by SUMO conjugation in the amino-terminal domain
    • DOI 10.1111/j.1365-2443.2004.00786.x
    • Yamashita D., Yamaguchi T., Shimizu M., Nakata N., Hirose F., Osumi T., The transactivating function of peroxisome proliferator-activated receptor is negatively regulated by SUMO conjugation in the amino-terminal domain Genes to Cells 2004 9 11 1017 1029 (Pubitemid 39467975)
    • (2004) Genes to Cells , vol.9 , Issue.11 , pp. 1017-1029
    • Yamashita, D.1    Yamaguchi, T.2    Shimizu, M.3    Nakata, N.4    Hirose, F.5    Osumi, T.6
  • 33
    • 84856008795 scopus 로고    scopus 로고
    • Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels
    • Yessoufou A., Wahli W., Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels Swiss Medical Weekly 2010 140 13071
    • (2010) Swiss Medical Weekly , vol.140 , pp. 13071
    • Yessoufou, A.1    Wahli, W.2
  • 34
    • 0030951143 scopus 로고    scopus 로고
    • Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARγ2 versus PPARγ1 and activation with retinoid X receptor agonists and antagonists
    • DOI 10.1074/jbc.272.12.8071
    • Mukherjee R., Jow L., Croston G. E., Paterniti J. R. Jr, Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPAR 2 versus PPAR 1 and activation with retinoid X receptor agonists and antagonists Journal of Biological Chemistry 1997 272 12 8071 8076 (Pubitemid 27137374)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.12 , pp. 8071-8076
    • Mukherjee, R.1    Jow, L.2    Croston, G.E.3    Paterniti Jr., J.R.4
  • 35
    • 33846833479 scopus 로고    scopus 로고
    • Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: Increase of lipid catabolism and reduction of adipokine expression
    • DOI 10.1007/s00125-006-0565-0
    • Wang P., Renes J., Bouwman F., Bunschoten A., Mariman E., Keijer J., Absence of an adipogenic effect of rosiglitazone on mature 3T3-L1 adipocytes: increase of lipid catabolism and reduction of adipokine expression Diabetologia 2007 50 3 654 665 (Pubitemid 46215510)
    • (2007) Diabetologia , vol.50 , Issue.3 , pp. 654-665
    • Wang, P.1    Renes, J.2    Bouwman, F.3    Bunschoten, A.4    Mariman, E.5    Keijer, J.6
  • 37
    • 36549051626 scopus 로고    scopus 로고
    • PPARγ physiology and pathology in gastrointestinal epithelial cells
    • Thompson E. A., PPAR physiology and pathology in gastrointestinal epithelial cells Molecules and Cells 2007 24 2 167 176 (Pubitemid 350177175)
    • (2007) Molecules and Cells , vol.24 , Issue.2 , pp. 167-176
    • Thompson, E.A.1
  • 39
    • 75149141045 scopus 로고    scopus 로고
    • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
    • Mann J., Chu D. C. K., Maxwell A., Oakley F., Zhu N. L., Tsukamoto H., Mann D. A., MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis Gastroenterology 2010 138 2 705 e4
    • (2010) Gastroenterology , vol.138 , Issue.2
    • Mann, J.1    Chu, D.C.K.2    Maxwell, A.3    Oakley, F.4    Zhu, N.L.5    Tsukamoto, H.6    Mann, D.A.7
  • 42
    • 0034121698 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ-dependent repression of the inducible nitric oxide synthase gene
    • DOI 10.1128/MCB.20.13.4699-4707.2000
    • Li M., Pascual G., Glass C. K., Peroxisome proliferator-activated receptor -dependent repression of the inducible nitric oxide synthase gene Molecular and Cellular Biology 2000 20 13 4699 4707 (Pubitemid 30396117)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.13 , pp. 4699-4707
    • Li, M.1    Pascual, G.2    Glass, C.K.3
  • 44
    • 26444471700 scopus 로고    scopus 로고
    • A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
    • DOI 10.1038/nature03988, PII N03988
    • Pascual G., Fong A. L., Ogawa S., Gamliel A., Li A. C., Perissi V., Rose D. W., Willson T. M., Rosenfeld M. G., Glass C. K., A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR- Nature 2005 437 7059 759 763 (Pubitemid 41486547)
    • (2005) Nature , vol.437 , Issue.7059 , pp. 759-763
    • Pascual, G.1    Fong, A.L.2    Ogawa, S.3    Gamliel, A.4    Li, A.C.5    Perissi, V.6    Rose, D.W.7    Willson, T.M.8    Rosenfeld, M.G.9    Glass, C.K.10
  • 45
    • 65549104658 scopus 로고    scopus 로고
    • A novel approach to anticancer therapies: Peroxisome proliferator activator-receptor- as a new target therapy in the treatment of human urological cancer
    • Matsuyama M., Yoshimura R., A novel approach to anticancer therapies: peroxisome proliferator activator-receptor- as a new target therapy in the treatment of human urological cancer Endocrine, Metabolic and Immune Disorders 2009 9 1 76 83
    • (2009) Endocrine, Metabolic and Immune Disorders , vol.9 , Issue.1 , pp. 76-83
    • Matsuyama, M.1    Yoshimura, R.2
  • 46
    • 27544433196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and ovarian function-implications for regulating steroidogenesis, differentiation, and tissue remodeling
    • Komar C. M., Peroxisome proliferator-activated receptors (PPARs) and ovarian function-implications for regulating steroidogenesis, differentiation, and tissue remodeling Reproductive Biology and Endocrinology 2005 3 41
    • (2005) Reproductive Biology and Endocrinology , vol.3 , pp. 41
    • Komar, C.M.1
  • 47
    • 0037899628 scopus 로고    scopus 로고
    • Use of the peroxisome proliferator-activated receptor (PPAR) γ ligand troglitazone as treatment for refractory breast cancer: A phase II study
    • DOI 10.1023/A:1024038127156
    • Burstein H. J., Demetri G. D., Mueller E., Sarraf P., Spiegelman B. M., Winer E. P., Use of the peroxisome proliferator-activated receptor (PPAR) ligand troglitazone as treatment for refractory breast cancer: a phase II study Breast Cancer Research and Treatment 2003 79 3 391 397 (Pubitemid 36750946)
    • (2003) Breast Cancer Research and Treatment , vol.79 , Issue.3 , pp. 391-397
    • Burstein, H.J.1    Demetri, G.D.2    Mueller, E.3    Sarraf, P.4    Spiegelman, B.M.5    Winer, E.P.6
  • 51
    • 0034161814 scopus 로고    scopus 로고
    • A ligand of peroxisome proliferator-activated receptor γ, retinoids, and prevention of preneoplastic mammary lesions
    • Mehta R. G., Williamson E., Patel M. K., Koeffler H. P., A ligand of peroxisome proliferator-activated receptor, retinoids, and prevention of preneoplastic mammary lesions Journal of the National Cancer Institute 2000 92 5 418 423 (Pubitemid 30154824)
    • (2000) Journal of the National Cancer Institute , vol.92 , Issue.5 , pp. 418-423
    • Mehta, R.G.1    Williamson, E.2    Patel, M.K.3    Koeffler, H.P.4
  • 53
    • 0037651115 scopus 로고    scopus 로고
    • PPAR-γ receptor ligands: Novel therapy for pituitary adenomas
    • DOI 10.1172/JCI200316575
    • Heaney A. P., Fernando M., Melmed S., PPAR- receptor ligands: novel therapy for pituitary adenomas Journal of Clinical Investigation 2003 111 9 1381 1388 (Pubitemid 36554709)
    • (2003) Journal of Clinical Investigation , vol.111 , Issue.9 , pp. 1381-1388
    • Heaney, A.P.1    Fernando, M.2    Melmed, S.3
  • 54
    • 0035019640 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptor γ inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells
    • DOI 10.1210/jc.86.5.2170
    • Ohta K., Endo T., Haraguchi K., Hershman J. M., Onaya T., Ligands for peroxisome proliferator-activated receptor inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells Journal of Clinical Endocrinology and Metabolism 2001 86 5 2170 2177 (Pubitemid 32472935)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.5 , pp. 2170-2177
    • Ohta, K.1    Endo, T.2    Haraguchi, K.3    Hershman, J.M.4    Onaya, T.5
  • 55
    • 0032145363 scopus 로고    scopus 로고
    • Ligand for peroxisome proliferator-activated receptor γ (Troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
    • Kubota T., Koshizuka K., Williamson E. A., Asou H., Said J. W., Holden S., Miyoshi I., Koeffler H. P., Ligand for peroxisome proliferator-activated receptor (Troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo Cancer Research 1998 58 15 3344 3352 (Pubitemid 28371075)
    • (1998) Cancer Research , vol.58 , Issue.15 , pp. 3344-3352
    • Kubota, T.1    Koshizuka, K.2    Williamson, E.A.3    Asou, H.4    Said, J.W.5    Holden, S.6    Miyoshi, I.7    Koeffler, H.P.8
  • 57
    • 1542313738 scopus 로고    scopus 로고
    • Induction of differentiation and peroxisome proliferator-activated receptor γ expression in colon cancer cell lines by troglitazone
    • DOI 10.1007/s00432-003-0510-2
    • Kato M., Kusumi T., Tsuchida S., Tanaka M., Sasaki M., Kudo H., Induction of differentiation and peroxisome proliferator-activated receptor expression in colon cancer cell lines by troglitazone Journal of Cancer Research and Clinical Oncology 2004 130 2 73 79 (Pubitemid 38316669)
    • (2004) Journal of Cancer Research and Clinical Oncology , vol.130 , Issue.2 , pp. 73-79
    • Kato, M.1    Kusumi, T.2    Tsuchida, S.3    Tanaka, M.4    Sasaki, M.5    Kudo, H.6
  • 60
    • 0034306992 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor by troglitazone inhibits cell growth through the increase of p27(Kip1) in human pancreatic carcinoma cells
    • Motomura W., Okumura T., Takahashi N., Obara T., Kohgo Y., Activation of peroxisome proliferator-activated receptor by troglitazone inhibits cell growth through the increase of p27(Kip1) in human pancreatic carcinoma cells Cancer Research 2000 60 19 5558 5564
    • (2000) Cancer Research , vol.60 , Issue.19 , pp. 5558-5564
    • Motomura, W.1    Okumura, T.2    Takahashi, N.3    Obara, T.4    Kohgo, Y.5
  • 61
    • 0037473753 scopus 로고    scopus 로고
    • Activation of PPARγ increases PTEN expression in pancreatic cancer cells
    • DOI 10.1016/S0006-291X(02)02983-2
    • Farrow B., Evers B. M., Activation of PPAR increases PTEN expression in pancreatic cancer cells Biochemical and Biophysical Research Communications 2003 301 1 50 53 (Pubitemid 36268846)
    • (2003) Biochemical and Biophysical Research Communications , vol.301 , Issue.1 , pp. 50-53
    • Farrow, B.1    Evers, B.M.2
  • 62
  • 63
    • 33751167878 scopus 로고    scopus 로고
    • PPAR activator rosiglitazone inhibits cell migration via upregulation of PTEN in human hepatocarcinoma cell line BEL-7404
    • Zhang W., Wu N., Li Z., Wang L., Jin J., Zha X. L., PPAR activator rosiglitazone inhibits cell migration via upregulation of PTEN in human hepatocarcinoma cell line BEL-7404 Cancer Biology and Therapy 2006 5 8 1008 1014
    • (2006) Cancer Biology and Therapy , vol.5 , Issue.8 , pp. 1008-1014
    • Zhang, W.1    Wu, N.2    Li, Z.3    Wang, L.4    Jin, J.5    Zha, X.L.6
  • 65
    • 0034623232 scopus 로고    scopus 로고
    • Feedback control of cyclooxygenase-2 expression through PPAR
    • Inoue H., Tanabe T., Umesono K., Feedback control of cyclooxygenase-2 expression through PPAR Journal of Biological Chemistry 2000 275 36 28028 28032
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.36 , pp. 28028-28032
    • Inoue, H.1    Tanabe, T.2    Umesono, K.3
  • 66
    • 0038703477 scopus 로고    scopus 로고
    • PPARγ ligands and ATRA inhibit the invasion of human breast cancer cells in vitro
    • DOI 10.1023/A:1023366117157
    • Liu H., Zang C., Fenner M. H., Possinger K., Elstner E., PPAR ligands and ATRA inhibit the invasion of human breast cancer cells in vitro Breast Cancer Research and Treatment 2003 79 1 63 74 (Pubitemid 36561044)
    • (2003) Breast Cancer Research and Treatment , vol.79 , Issue.1 , pp. 63-74
    • Liu, H.1    Zang, C.2    Fenner, M.H.3    Possinger, K.4    Elstner, E.5
  • 67
    • 34250773317 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ agonists inhibit the proliferation and invasion of human colon cancer cells
    • DOI 10.1136/pmj.2006.052761
    • Shen D., Deng C., Zhang M., Peroxisome proliferator-activated receptor agonists inhibit the proliferation and invasion of human colon cancer cells Postgraduate Medical Journal 2007 83 980 414 419 (Pubitemid 46960828)
    • (2007) Postgraduate Medical Journal , vol.83 , Issue.980 , pp. 414-419
    • Shen, D.1    Deng, C.2    Zhang, M.3
  • 68
    • 0037470070 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ and transforming growth factor-β pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22
    • DOI 10.1074/jbc.M208076200
    • Gupta R. A., Sarraf P., Brockman J. A., Shappell S. B., Raftery L. A., Willson T. M., DuBois R. N., Peroxisome proliferator-activated receptor and transforming growth factor- pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22 Journal of Biological Chemistry 2003 278 9 7431 7438 (Pubitemid 36800748)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.9 , pp. 7431-7438
    • Gupta, R.A.1    Sarraf, P.2    Brockman, J.A.3    Shappell, S.B.4    Raftery, L.A.5    Willson, T.M.6    DuBois, R.N.7
  • 69
    • 0037192702 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-γ stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells
    • DOI 10.1038/sj.onc.1205279
    • Satoh T., Toyoda M., Hoshino H., Monden T., Yamada M., Shimizu H., Miyamoto K., Mori M., Activation of peroxisome proliferator-activated receptor- stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells Oncogene 2002 21 14 2171 2180 (Pubitemid 34311371)
    • (2002) Oncogene , vol.21 , Issue.14 , pp. 2171-2180
    • Satoh, T.1    Toyoda, M.2    Hoshino, H.3    Monden, T.4    Yamada, M.5    Shimizu, H.6    Miyamoto, K.7    Mori, M.8
  • 70
    • 0037134255 scopus 로고    scopus 로고
    • Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and Nf-kB in human colon cancer
    • DOI 10.1016/S0024-3205(02)01510-2, PII S0024320502015102
    • Chen G. G., Lee J. F. Y., Wang S. H., Chan U. P. F., Ip P. C., Lau W. Y., Apoptosis induced by activation of peroxisome-proliferator activated receptor- is associated with Bcl-2 and Nf-kB in human colon cancer Life Sciences 2002 70 22 2631 2646 (Pubitemid 34310556)
    • (2002) Life Sciences , vol.70 , Issue.22 , pp. 2631-2646
    • Chen, G.G.1    Lee, J.F.Y.2    Wang, S.H.3    Chan, U.P.F.4    Ip, P.C.5    Lau, W.Y.6
  • 71
    • 0033605677 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands are potent inhibitors of angiogenesis in vitro and in vivo
    • DOI 10.1074/jbc.274.13.9116
    • Xin X., Yang S., Kowalski J., Gerritsen M. E., Peroxisome proliferator-activated receptor ligands are potent inhibitors of angiogenesis in vitro and in vivo Journal of Biological Chemistry 1999 274 13 9116 9121 (Pubitemid 29164719)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.13 , pp. 9116-9121
    • Xin, X.1    Yang, S.2    Kowalski, J.3    Gerritsen, M.E.4
  • 73
    • 2442455744 scopus 로고    scopus 로고
    • Increased Nuclear Factor-kB Activation in Human Colorectal Carcinoma and its Correlation with Tumor Progression
    • Kojima M., Morisaki T., Sasaki N., Nakano K., Mibu R., Tanaka M., Katano M., Increased nuclear factor- B activation in human colorectal carcinoma and its correlation with tumor progression Anticancer Research B 2004 24 2 675 681 (Pubitemid 38625006)
    • (2004) Anticancer Research , vol.24 , Issue.2 , pp. 675-681
    • Kojima, M.1    Morisaki, T.2    Sasaki, N.3    Nakano, K.4    Mibu, R.5    Tanaka, M.6    Katano, M.7
  • 74
    • 80054883778 scopus 로고    scopus 로고
    • Beneficial effects of THSG on acetic acid-induced experimental colitis: Involvement of upregulation of PPAR and inhibition of the Nf- B inflammatory pathway
    • Zeng C., Xiao J. H., Chang M. J., Wang J. L., Beneficial effects of THSG on acetic acid-induced experimental colitis: involvement of upregulation of PPAR and inhibition of the Nf- B inflammatory pathway Molecules 2011 16 10 8552 8568
    • (2011) Molecules , vol.16 , Issue.10 , pp. 8552-8568
    • Zeng, C.1    Xiao, J.H.2    Chang, M.J.3    Wang, J.L.4
  • 75
  • 76
    • 78650450648 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-g activation inhibits tumor metastasis by antagonizing smad3-mediated epithelial-mesenchymal transition
    • Reka A. K., Kurapati H., Narala V. R., Bommer G., Chen J., Standiford T. J., Keshamouni V. G., Peroxisome proliferator-activated receptor-g activation inhibits tumor metastasis by antagonizing smad3-mediated epithelial-mesenchymal transition Molecular Cancer Therapeutics 2010 9 12 3221 3232
    • (2010) Molecular Cancer Therapeutics , vol.9 , Issue.12 , pp. 3221-3232
    • Reka, A.K.1    Kurapati, H.2    Narala, V.R.3    Bommer, G.4    Chen, J.5    Standiford, T.J.6    Keshamouni, V.G.7
  • 80
    • 76049105429 scopus 로고    scopus 로고
    • Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: Molecular mechanisms and therapeutic perspectives
    • Menendez J. A., Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives Biochimica et Biophysica Acta 2010 1801 3 381 391
    • (2010) Biochimica et Biophysica Acta , vol.1801 , Issue.3 , pp. 381-391
    • Menendez, J.A.1
  • 81
    • 84865226215 scopus 로고    scopus 로고
    • MiR-27b targets PPAR to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells
    • In press
    • Lee J., Drakaki A., Iliopoulos D., Struhl K., MiR-27b targets PPAR to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells. Oncogene. In press
    • Oncogene
    • Lee, J.1    Drakaki, A.2    Iliopoulos, D.3    Struhl, K.4
  • 82
    • 34548069753 scopus 로고    scopus 로고
    • Differential expression, distribution, and function of PPAR-γ in the proximal and distal colon
    • DOI 10.1152/physiolgenomics.00042.2007
    • Su W., Bush C. R., Necela B. M., Calcagno S. R., Murray N. R., Fields A. P., Thompson E. A., Differential expression, distribution, and function of PPAR- in the proximal and distal colon Physiological Genomics 2007 30 3 342 353 (Pubitemid 47296193)
    • (2007) Physiological Genomics , vol.30 , Issue.3 , pp. 342-353
    • Su, W.1    Bush, C.R.2    Necela, B.M.3    Calcagno, S.R.4    Murray, N.R.5    Fields, A.P.6    Thompson, E.A.7
  • 83
    • 11844273837 scopus 로고    scopus 로고
    • Colorectal cancer
    • DOI 10.1016/S0140-6736(05)17706-X, PII S014067360517706X
    • Weitz J., Koch M., Debus J., Hhler T., Galle P. R., Bchler M. W., Colorectal cancer Lancet 2005 365 9454 153 165 (Pubitemid 40091806)
    • (2005) Lancet , vol.365 , Issue.9454 , pp. 153-165
    • Weitz, J.1    Koch, M.2    Debus, J.3    Hohler, T.4    Galle, P.R.5    Buchler, M.W.6
  • 85
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
    • Lefebvre M., Paulweber B., Fajas L., Activation of the peroxisome proliferator-activated receptor promotes the development of colon tumors in C57BL/6J-APCMin/+ mice Nature Medicine 1998 4 9 1053 1057
    • (1998) Nature Medicine , vol.4 , Issue.9 , pp. 1053-1057
    • Lefebvre, M.1    Paulweber, B.2    Fajas, L.3
  • 86
    • 0141842617 scopus 로고    scopus 로고
    • Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands
    • Niho N., Takahashi M., Kitamura T., Shoji Y., Itoh M., Noda T., Sugimura T., Wakabayashi K., Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands Cancer Research 2003 63 18 6090 6095 (Pubitemid 37187515)
    • (2003) Cancer Research , vol.63 , Issue.18 , pp. 6090-6095
    • Niho, N.1    Takahashi, M.2    Kitamura, T.3    Shoji, Y.4    Itoh, M.5    Noda, T.6    Sugimura, T.7    Wakabayashi, K.8
  • 87
    • 0345099451 scopus 로고    scopus 로고
    • Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPARγ ligand
    • DOI 10.1111/j.1349-7006.2003.tb01385.x
    • Niho N., Takahashi M., Shoji Y., Takeuchi Y., Matsubara S., Sugimura T., Wakabayashi K., Dose-dependent suppression of hyperlipidemia and intestinal polyp formation in Min mice by pioglitazone, a PPAR ligand Cancer Science 2003 94 11 960 964 (Pubitemid 37508978)
    • (2003) Cancer Science , vol.94 , Issue.11 , pp. 960-964
    • Niho, N.1    Takahashi, M.2    Shoji, Y.3    Takeuchi, Y.4    Matsubara, S.5    Sugimura, T.6    Wakabayashi, K.7
  • 89
    • 34548159455 scopus 로고    scopus 로고
    • Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor γ and calcium signaling in human colorectal cancer cells
    • DOI 10.1074/jbc.M702708200
    • Bush C. R., Havens J. M., Necela B. M., Su W., Chen L., Yanagisawa M., Anastasiadis P. Z., Guerra R., Luxon B. A., Thompson E. A., Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor and calcium signaling in human colorectal cancer cells Journal of Biological Chemistry 2007 282 32 23387 23401 (Pubitemid 47311964)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.32 , pp. 23387-23401
    • Bush, C.R.1    Havens, J.M.2    Necela, B.M.3    Su, W.4    Chen, L.5    Yanagisawa, M.6    Anastasiadis, P.Z.7    Guerra, R.8    Luxon, B.A.9    Thompson, E.A.10
  • 90
    • 0038265387 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ-mediated differentiation: A mutation in colon cancer cells reveals divergent and cell type-specific mechanisms
    • DOI 10.1074/jbc.M300637200
    • Gupta R. A., Sarraf P., Mueller E., Brockman J. A., Prusakiewicz J. J., Eng C., Willson T. M., DuBois R. N., Peroxisome proliferator-activated receptor -mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms Journal of Biological Chemistry 2003 278 25 22669 22677 (Pubitemid 36830326)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22669-22677
    • Gupta, R.A.1    Sarraf, P.2    Mueller, E.3    Brockman, J.A.4    Prusakiewicz, J.J.5    Eng, C.6    Willson, T.M.7    DuBois, R.N.8
  • 91
    • 16644393169 scopus 로고    scopus 로고
    • Thiazolidinedione, a peroxisome proliferator-activated receptor- ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects
    • Yoshizumi T., Ohta T., Ninomiya I., Terada I., Fushida S., Fujimura T., Nishimura G. I., Shimizu K., Yi S., Miwa K., Thiazolidinedione, a peroxisome proliferator-activated receptor- ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects International journal of oncology 2004 25 3 631 639
    • (2004) International Journal of Oncology , vol.25 , Issue.3 , pp. 631-639
    • Yoshizumi, T.1    Ohta, T.2    Ninomiya, I.3    Terada, I.4    Fushida, S.5    Fujimura, T.6    Nishimura, G.I.7    Shimizu, K.8    Yi, S.9    Miwa, K.10
  • 92
    • 0035021875 scopus 로고    scopus 로고
    • Troglitazone, a ligand for peroxisome proliferator-activated receptor γ, inhibits chemically-induced aberrant crypt foci in rats
    • Kohno H., Yoshitani S., Takashima S., Okumura A., Hosokawa M., Yamaguchi N., Tanaka T., Troglitazone, a ligand for peroxisome proliferator-activated receptor, inhibits chemically-induced aberrant crypt foci in rats Japanese Journal of Cancer Research 2001 92 4 396 403 (Pubitemid 32427775)
    • (2001) Japanese Journal of Cancer Research , vol.92 , Issue.4 , pp. 396-403
    • Kohno, H.1    Yoshitani, S.2    Takashima, S.3    Okumura, A.4    Hosokawa, M.5    Yamaguchi, N.6    Tanaka, T.7
  • 93
    • 0035866756 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptors α and γ inhibit chemically induced colitis and formation of aberrant crypt foci in rats
    • Tanaka T., Kohno H., Yoshitani S. I., Takashima S., Okumura A., Murakami A., Hosokawa M., Ligands for peroxisome proliferator-activated receptors and inhibit chemically induced colitis and formation of aberrant crypt foci in rats Cancer Research 2001 61 6 2424 2428 (Pubitemid 32685818)
    • (2001) Cancer Research , vol.61 , Issue.6 , pp. 2424-2428
    • Tanaka, T.1    Kohno, H.2    Yoshitani, S.-I.3    Takashima, S.4    Okumura, A.5    Murakami, A.6    Hosokawa, M.7
  • 95
    • 0035881317 scopus 로고    scopus 로고
    • Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation
    • Palakurthi S. S., Aktas H., Grubissich L. M., Mortensen R. M., Halperin J. A., Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor and mediated by inhibition of translation initiation Cancer Research 2001 61 16 6213 6218 (Pubitemid 32762559)
    • (2001) Cancer Research , vol.61 , Issue.16 , pp. 6213-6218
    • Palakurthi, S.S.1    Aktas, H.2    Grubissich, L.M.3    Mortensen, R.M.4    Halperin, J.A.5
  • 98
    • 17644394616 scopus 로고    scopus 로고
    • Smoldering and polarized inflammation in the initiation and promotion of malignant disease
    • DOI 10.1016/j.ccr.2005.02.013
    • Balkwill F., Charles K. A., Mantovani A., Smoldering and polarized inflammation in the initiation and promotion of malignant disease Cancer Cell 2005 7 3 211 217 (Pubitemid 40568680)
    • (2005) Cancer Cell , vol.7 , Issue.3 , pp. 211-217
    • Balkwill, F.1    Charles, K.A.2    Mantovani, A.3
  • 99
    • 80655148899 scopus 로고    scopus 로고
    • Colitis-associated cancer: The dark side of inflammatory bowel disease
    • Danese S., Malesci A., Vetrano S., Colitis-associated cancer: the dark side of inflammatory bowel disease Gut 2011 60 12 1609 1610
    • (2011) Gut , vol.60 , Issue.12 , pp. 1609-1610
    • Danese, S.1    Malesci, A.2    Vetrano, S.3
  • 100
    • 33847039159 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor- in macrophage suppresses experimentally induced colitis
    • Shah Y. M., Morimura K., Gonzalez F. J., Expression of peroxisome proliferator-activated receptor- in macrophage suppresses experimentally induced colitis American Journal of Physiology 2007 292 2 G657 G666
    • (2007) American Journal of Physiology , vol.292 , Issue.2
    • Shah, Y.M.1    Morimura, K.2    Gonzalez, F.J.3
  • 103
    • 34548289084 scopus 로고    scopus 로고
    • MAPK kinases as nucleo-cytoplasmic shuttles for PPARγ
    • Burgermeister E., Seger R., MAPK kinases as nucleo-cytoplasmic shuttles for PPAR Cell Cycle 2007 6 13 1539 1548 (Pubitemid 47327937)
    • (2007) Cell Cycle , vol.6 , Issue.13 , pp. 1539-1548
    • Burgermeister, E.1    Seger, R.2
  • 105
    • 64049092259 scopus 로고    scopus 로고
    • Reduced beta-catenin and peroxisome proliferator-activated receptor- expression levels are associated with colorectal cancer metastatic progressione: Correlation with tumor-associated macrophages, cyclooxygenase 2 and patient outcome
    • Pancione M., Forte N., Sabatino L., Reduced beta-catenin and peroxisome proliferator-activated receptor- expression levels are associated with colorectal cancer metastatic progressione: correlation with tumor-associated macrophages, cyclooxygenase 2 and patient outcome Human Pathology 2009 40 5 714 725
    • (2009) Human Pathology , vol.40 , Issue.5 , pp. 714-725
    • Pancione, M.1    Forte, N.2    Sabatino, L.3
  • 107
    • 78149478781 scopus 로고    scopus 로고
    • Aberrant epigenetic landscape in cancer: How cellular identity goes awry
    • Berdasco M., Esteller M., Aberrant epigenetic landscape in cancer: how cellular identity goes awry Developmental Cell 2010 19 5 698 711
    • (2010) Developmental Cell , vol.19 , Issue.5 , pp. 698-711
    • Berdasco, M.1    Esteller, M.2
  • 108
    • 79960556965 scopus 로고    scopus 로고
    • Epigenome-wide association studies for common human diseases
    • Rakyan V. K., Down T. A., Balding D. J., Beck S., Epigenome-wide association studies for common human diseases Nature Reviews Genetics 2011 12 8 529 541
    • (2011) Nature Reviews Genetics , vol.12 , Issue.8 , pp. 529-541
    • Rakyan, V.K.1    Down, T.A.2    Balding, D.J.3    Beck, S.4
  • 110
    • 78049443505 scopus 로고    scopus 로고
    • Epigenomics of human colon cancer
    • Carmona F. J., Esteller M., Epigenomics of human colon cancer Mutation Research 2010 693 1-2 53 60
    • (2010) Mutation Research , vol.693 , Issue.12 , pp. 53-60
    • Carmona, F.J.1    Esteller, M.2
  • 111
    • 0033680062 scopus 로고    scopus 로고
    • Epigenetic lesions causing genetic lesions in human cancer: Promoter hypermethylation of DNA repair genes
    • Esteller M., Epigenetic lesions causing genetic lesions in human cancer: promoter hypermethylation of DNA repair genes European Journal of Cancer 2000 36 18 2294 2300
    • (2000) European Journal of Cancer , vol.36 , Issue.18 , pp. 2294-2300
    • Esteller, M.1
  • 112
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg A. P., Tycko B., The history of cancer epigenetics Nature Reviews Cancer 2004 4 2 143 153 (Pubitemid 38198742)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 114
    • 58149147370 scopus 로고    scopus 로고
    • Colon cancer: It's CIN or CIMP
    • Issa J. P., Colon cancer: it's CIN or CIMP Clinical Cancer Research 2008 14 19 5939 5940
    • (2008) Clinical Cancer Research , vol.14 , Issue.19 , pp. 5939-5940
    • Issa, J.P.1
  • 115
    • 70349742486 scopus 로고    scopus 로고
    • DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer
    • Jin B., Yao B., Li J. L., Fields C. R., Delmas A. L., Liu C., Robertson K. D., DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer Cancer Research 2009 69 18 7412 7421
    • (2009) Cancer Research , vol.69 , Issue.18 , pp. 7412-7421
    • Jin, B.1    Yao, B.2    Li, J.L.3    Fields, C.R.4    Delmas, A.L.5    Liu, C.6    Robertson, K.D.7
  • 116
    • 22744434740 scopus 로고    scopus 로고
    • De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases
    • DOI 10.1021/bi047634t
    • Gowher H., Stockdale C. J., Goyal R., Ferreira H., Owen-Hughes T., Jeltsch A., De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases Biochemistry 2005 44 29 9899 9904 (Pubitemid 41033456)
    • (2005) Biochemistry , vol.44 , Issue.29 , pp. 9899-9904
    • Gowher, H.1    Stockdale, C.J.2    Goyal, R.3    Ferreira, H.4    Owen-Hughes, T.5    Jeltsch, A.6
  • 119
    • 78650582970 scopus 로고    scopus 로고
    • Histone lysine methylation and demethylation pathways in cancer
    • Varier R. A., Timmers H. T. M., Histone lysine methylation and demethylation pathways in cancer Biochimica et Biophysica Acta 2011 1815 1 75 89
    • (2011) Biochimica et Biophysica Acta , vol.1815 , Issue.1 , pp. 75-89
    • Varier, R.A.1    Timmers, H.T.M.2
  • 120
    • 10744230544 scopus 로고    scopus 로고
    • Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
    • DOI 10.1016/S0960-9822(03)00432-9
    • Lehnertz B., Ueda Y., Derijck A. A. H. A., Braunschweig U., Perez-Burgos L., Kubicek S., Chen T., Li E., Jenuwein T., Peters A. H. F. M., Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin Current Biology 2003 13 14 1192 1200 (Pubitemid 36872941)
    • (2003) Current Biology , vol.13 , Issue.14 , pp. 1192-1200
    • Lehnertz, B.1    Ueda, Y.2    Derijck, A.A.H.A.3    Braunschweig, U.4    Perez-Burgos, L.5    Kubicek, S.6    Chen, T.7    Li, E.8    Jenuwein, T.9    Peters, A.H.F.M.10
  • 124
    • 44649139771 scopus 로고    scopus 로고
    • Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation
    • Shilatifard A., Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation Current Opinion in Cell Biology 2008 20 3 341 348
    • (2008) Current Opinion in Cell Biology , vol.20 , Issue.3 , pp. 341-348
    • Shilatifard, A.1
  • 125
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Portela A., Esteller M., Epigenetic modifications and human disease Nature Biotechnology 2010 28 10 1057 1068
    • (2010) Nature Biotechnology , vol.28 , Issue.10 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 126
    • 47849083984 scopus 로고    scopus 로고
    • Epigenetic interplay between histone modifications and DNA methylation in gene silencing
    • Vaissire T., Sawan C., Herceg Z., Epigenetic interplay between histone modifications and DNA methylation in gene silencing Mutation Research 2008 659 1-2 40 48
    • (2008) Mutation Research , vol.659 , Issue.12 , pp. 40-48
    • Vaissire, T.1    Sawan, C.2    Herceg, Z.3
  • 131
    • 80054790280 scopus 로고    scopus 로고
    • The roles of the methyl-CpG binding proteins in cancer
    • Parry L., Clarke A. R., The roles of the methyl-CpG binding proteins in cancer Genes and Cancer 2011 2 6 618 630
    • (2011) Genes and Cancer , vol.2 , Issue.6 , pp. 618-630
    • Parry, L.1    Clarke, A.R.2
  • 132
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • DOI 10.1038/30764
    • Nan X., Ng H. H., Johnson C. A., Laherty C. D., Turner B. M., Eisenman R. N., Bird A., Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex Nature 1998 393 6683 386 389 (Pubitemid 28269714)
    • (1998) Nature , vol.393 , Issue.6683 , pp. 386-389
    • Nan, X.1    Ng, H.-H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 136
    • 80054029971 scopus 로고    scopus 로고
    • Long non-coding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers
    • Kogo R., Shimamura T., Mimori K., Long non-coding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers Cancer Research 2011 71 20 6320 6326
    • (2011) Cancer Research , vol.71 , Issue.20 , pp. 6320-6326
    • Kogo, R.1    Shimamura, T.2    Mimori, K.3
  • 137
    • 79953888460 scopus 로고    scopus 로고
    • The functional role of long non-coding RNA in human carcinomas
    • Gibb E. A., Brown C. J., Lam W. L., The functional role of long non-coding RNA in human carcinomas Molecular Cancer 2011 10 38
    • (2011) Molecular Cancer , vol.10 , pp. 38
    • Gibb, E.A.1    Brown, C.J.2    Lam, W.L.3
  • 138
    • 68249139820 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator activated receptor gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes
    • Fujiki K., Kano F., Shiota K., Murata M., Expression of the peroxisome proliferator activated receptor gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes BMC Biology 2009 7 38
    • (2009) BMC Biology , vol.7 , pp. 38
    • Fujiki, K.1    Kano, F.2    Shiota, K.3    Murata, M.4
  • 139
    • 2442691703 scopus 로고    scopus 로고
    • Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor γ nuclear hormone receptor
    • DOI 10.1128/MCB.24.11.4651-4663.2004
    • Salma N., Xiao H., Mueller E., Imbalzano A. N., Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor nuclear hormone receptor Molecular and Cellular Biology 2004 24 11 4651 4663 (Pubitemid 38668033)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.11 , pp. 4651-4663
    • Salma, N.1    Xiao, H.2    Mueller, E.3    Imbalzano, A.N.4
  • 140
    • 33846200332 scopus 로고    scopus 로고
    • Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: Implications for wound healing and fibrogenesis
    • DOI 10.1038/sj.cdd.4401979, PII 4401979
    • Mann J., Oakley F., Akiboye F., Elsharkawy A., Thorne A. W., Mann D. A., Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis Cell Death and Differentiation 2007 14 2 275 285 (Pubitemid 46092230)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.2 , pp. 275-285
    • Mann, J.1    Oakley, F.2    Akiboye, F.3    Elsharkawy, A.4    Thorne, A.W.5    Mann, D.A.6
  • 143
    • 84862649418 scopus 로고    scopus 로고
    • Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death
    • Rogers H. A., Kilday J. P., Mayne C., Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death Acta Neuropathologica 2012 123 5 711 725
    • (2012) Acta Neuropathologica , vol.123 , Issue.5 , pp. 711-725
    • Rogers, H.A.1    Kilday, J.P.2    Mayne, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.