Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

Nature Genetics

Volumn 40, Issue 6, 2008, Pages 741-750

  Kondo, Yutaka ^a,b   Shen, Lanlan ^a   Cheng, Alfred S ^c,f   Ahmed, Saira ^a   Boumber, Yanis ^a   Charo, Chantale ^a   Yamochi, Tadanori ^a   Urano, Takeshi ^d   Furukawa, Koichi ^d   Kwabi Addo, Bernard ^e   Gold, David L ^a   Sekido, Yoshitaka ^b   Huang, Tim Hui Ming ^c   Issa, Jean Pierre J ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

^c OHIO STATE UNIVERSITY   (United States)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

BMI1 PROTEIN; HISTONE H3; LYSINE;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; GENE SILENCING; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NEOPLASM; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLATION; ALKALINE PHOSPHATASE; BREAST NEOPLASMS; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; COLONY-FORMING UNITS ASSAY; CPG ISLANDS; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; GENE SILENCING; HISTONES; HUMANS; LUNG NEOPLASMS; LYSINE; MALE; MICROARRAY ANALYSIS; MICROFILAMENT PROTEINS; PROMOTER REGIONS (GENETICS); PROSTATE; PROSTATIC NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 44349131472     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.159     Document Type: Article

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