메뉴 건너뛰기




Volumn 19, Issue 5, 2010, Pages 698-711

Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; MICRORNA;

EID: 78149478781     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2010.10.005     Document Type: Review
Times cited : (491)

References (181)
  • 1
    • 34147138648 scopus 로고    scopus 로고
    • Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
    • Akimzhanov A.M., Yang X.O., Dong C. Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J. Biol. Chem. 2007, 282:5969-5972.
    • (2007) J. Biol. Chem. , vol.282 , pp. 5969-5972
    • Akimzhanov, A.M.1    Yang, X.O.2    Dong, C.3
  • 5
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004, 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 6
    • 0035872769 scopus 로고    scopus 로고
    • NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines
    • Angrand P.O., Apiou F., Stewart A.F., Dutrillaux B., Losson R., Chambon P. NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. Genomics 2001, 74:79-88.
    • (2001) Genomics , vol.74 , pp. 79-88
    • Angrand, P.O.1    Apiou, F.2    Stewart, A.F.3    Dutrillaux, B.4    Losson, R.5    Chambon, P.6
  • 7
    • 0042329754 scopus 로고    scopus 로고
    • Structure, function and evolution of CpG island promoters
    • Antequera F. Structure, function and evolution of CpG island promoters. Cell. Mol. Life Sci. 2003, 60:1647-1658.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 1647-1658
    • Antequera, F.1
  • 11
    • 22544437866 scopus 로고    scopus 로고
    • Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation
    • Benbrahim-Tallaa L., Waterland R.A., Styblo M., Achanzar W.E., Webber M.M., Waalkes M.P. Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation. Toxicol. Appl. Pharmacol. 2005, 206:288-298.
    • (2005) Toxicol. Appl. Pharmacol. , vol.206 , pp. 288-298
    • Benbrahim-Tallaa, L.1    Waterland, R.A.2    Styblo, M.3    Achanzar, W.E.4    Webber, M.M.5    Waalkes, M.P.6
  • 19
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken A.P., Pasini D., Capra M., Prosperini E., Colli E., Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J. 2003, 22:5323-5335.
    • (2003) EMBO J. , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 21
    • 0042091987 scopus 로고    scopus 로고
    • A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus
    • Bulger M., Schübeler D., Bender M.A., Hamilton J., Farrell C.M., Hardison R.C., Groudine M. A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus. Mol. Cell. Biol. 2003, 23:5234-5244.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5234-5244
    • Bulger, M.1    Schübeler, D.2    Bender, M.A.3    Hamilton, J.4    Farrell, C.M.5    Hardison, R.C.6    Groudine, M.7
  • 22
    • 18444361838 scopus 로고    scopus 로고
    • DNA methylation and chromatin structure: the puzzling CpG islands
    • Caiafa P., Zampieri M. DNA methylation and chromatin structure: the puzzling CpG islands. J. Cell. Biochem. 2005, 94:257-265.
    • (2005) J. Cell. Biochem. , vol.94 , pp. 257-265
    • Caiafa, P.1    Zampieri, M.2
  • 23
    • 1642296732 scopus 로고    scopus 로고
    • ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia
    • Canaani E., Nakamura T., Rozovskaia T., Smith S.T., Mori T., Croce C.M., Mazo A. ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia. Br. J. Cancer 2004, 90:756-760.
    • (2004) Br. J. Cancer , vol.90 , pp. 756-760
    • Canaani, E.1    Nakamura, T.2    Rozovskaia, T.3    Smith, S.T.4    Mori, T.5    Croce, C.M.6    Mazo, A.7
  • 25
    • 0042379770 scopus 로고    scopus 로고
    • Chromatin of the Barr body: histone and non-histone proteins associated with or excluded from the inactive X chromosome
    • Chadwick B.P., Willard H.F. Chromatin of the Barr body: histone and non-histone proteins associated with or excluded from the inactive X chromosome. Hum. Mol. Genet. 2003, 12:2167-2178.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2167-2178
    • Chadwick, B.P.1    Willard, H.F.2
  • 27
    • 44349162752 scopus 로고    scopus 로고
    • Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
    • Chang H.H., Hemberg M., Barahona M., Ingber D.E., Huang S. Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature 2008, 453:544-547.
    • (2008) Nature , vol.453 , pp. 544-547
    • Chang, H.H.1    Hemberg, M.2    Barahona, M.3    Ingber, D.E.4    Huang, S.5
  • 28
    • 12344266614 scopus 로고    scopus 로고
    • 5-azacytidine induces cardiac differentiation of P19 embryonic stem cells
    • Choi S.C., Yoon J., Shim W.J., Ro Y.M., Lim D.S. 5-azacytidine induces cardiac differentiation of P19 embryonic stem cells. Exp. Mol. Med. 2004, 36:515-523.
    • (2004) Exp. Mol. Med. , vol.36 , pp. 515-523
    • Choi, S.C.1    Yoon, J.2    Shim, W.J.3    Ro, Y.M.4    Lim, D.S.5
  • 32
    • 77953540361 scopus 로고    scopus 로고
    • Epigenomics of T cell activation, differentiation, and memory
    • Cuddapah S., Barski A., Zhao K. Epigenomics of T cell activation, differentiation, and memory. Curr. Opin. Immunol. 2010, 22:341-347.
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 341-347
    • Cuddapah, S.1    Barski, A.2    Zhao, K.3
  • 33
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • Cui K., Zang C., Roh T.Y., Schones D.E., Childs R.W., Peng W., Zhao K. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 2009, 4:80-93.
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1    Zang, C.2    Roh, T.Y.3    Schones, D.E.4    Childs, R.W.5    Peng, W.6    Zhao, K.7
  • 35
    • 0032694084 scopus 로고    scopus 로고
    • DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter
    • De Smet C., Lurquin C., Lethé B., Martelange V., Boon T. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol. Cell. Biol. 1999, 19:7327-7335.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7327-7335
    • De Smet, C.1    Lurquin, C.2    Lethé, B.3    Martelange, V.4    Boon, T.5
  • 36
    • 2442654138 scopus 로고    scopus 로고
    • Promoter-dependent mechanism leading to selective hypomethylation within the 5′ region of gene MAGE-A1 in tumor cells
    • De Smet C., Loriot A., Boon T. Promoter-dependent mechanism leading to selective hypomethylation within the 5′ region of gene MAGE-A1 in tumor cells. Mol. Cell. Biol. 2004, 24:4781-4790.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4781-4790
    • De Smet, C.1    Loriot, A.2    Boon, T.3
  • 37
  • 38
    • 57349163599 scopus 로고    scopus 로고
    • Relationship of SNCG, S100A4, S100A9 and LCN2 gene expression and DNA methylation in bladder cancer
    • Dokun O.Y., Florl A.R., Seifert H.H., Wolff I., Schulz W.A. Relationship of SNCG, S100A4, S100A9 and LCN2 gene expression and DNA methylation in bladder cancer. Int. J. Cancer 2008, 123:2798-2807.
    • (2008) Int. J. Cancer , vol.123 , pp. 2798-2807
    • Dokun, O.Y.1    Florl, A.R.2    Seifert, H.H.3    Wolff, I.4    Schulz, W.A.5
  • 39
    • 34247109637 scopus 로고    scopus 로고
    • Epigenetic gene regulation: linking early developmental environment to adult disease
    • Dolinoy D.C., Weidman J.R., Jirtle R.L. Epigenetic gene regulation: linking early developmental environment to adult disease. Reprod. Toxicol. 2007, 23:297-307.
    • (2007) Reprod. Toxicol. , vol.23 , pp. 297-307
    • Dolinoy, D.C.1    Weidman, J.R.2    Jirtle, R.L.3
  • 40
    • 0035890771 scopus 로고    scopus 로고
    • Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily
    • Du Y., Carling T., Fang W., Piao Z., Sheu J.C., Huang S. Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily. Cancer Res. 2001, 61:8094-8099.
    • (2001) Cancer Res. , vol.61 , pp. 8094-8099
    • Du, Y.1    Carling, T.2    Fang, W.3    Piao, Z.4    Sheu, J.C.5    Huang, S.6
  • 42
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • Eden A., Gaudet F., Waghmare A., Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003, 300:455.
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 44
    • 13144251125 scopus 로고    scopus 로고
    • DNA methylation and cancer therapy: new developments and expectations
    • Esteller M. DNA methylation and cancer therapy: new developments and expectations. Curr. Opin. Oncol. 2005, 17:55-60.
    • (2005) Curr. Opin. Oncol. , vol.17 , pp. 55-60
    • Esteller, M.1
  • 45
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 2007, 8:286-298.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 286-298
    • Esteller, M.1
  • 46
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M. Epigenetics in cancer. N. Engl. J. Med. 2008, 358:1148-1159.
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 50
    • 34047093266 scopus 로고    scopus 로고
    • Convergent evolution of genomic imprinting in plants and mammals
    • Feil R., Berger F. Convergent evolution of genomic imprinting in plants and mammals. Trends Genet. 2007, 23:192-199.
    • (2007) Trends Genet. , vol.23 , pp. 192-199
    • Feil, R.1    Berger, F.2
  • 51
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg A.P., Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983, 301:89-92.
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 54
    • 58149144779 scopus 로고    scopus 로고
    • Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells
    • Fiskus W., Wang Y., Joshi R., Rao R., Yang Y., Chen J., Kolhe R., Balusu R., Eaton K., Lee P., et al. Cotreatment with vorinostat enhances activity of MK-0457 (VX-680) against acute and chronic myelogenous leukemia cells. Clin. Cancer Res. 2008, 14:6106-6115.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6106-6115
    • Fiskus, W.1    Wang, Y.2    Joshi, R.3    Rao, R.4    Yang, Y.5    Chen, J.6    Kolhe, R.7    Balusu, R.8    Eaton, K.9    Lee, P.10
  • 57
    • 77952299722 scopus 로고    scopus 로고
    • MiR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
    • Furuta M., Kozaki K.I., Tanaka S., Arii S., Imoto I., Inazawa J. miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 2010, 31:766-776.
    • (2010) Carcinogenesis , vol.31 , pp. 766-776
    • Furuta, M.1    Kozaki, K.I.2    Tanaka, S.3    Arii, S.4    Imoto, I.5    Inazawa, J.6
  • 59
    • 67650588646 scopus 로고    scopus 로고
    • MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
    • Garzon R., Liu S., Fabbri M., Liu Z., Heaphy C.E., Callegari E., Schwind S., Pang J., Yu J., Muthusamy N., et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009, 113:6411-6418.
    • (2009) Blood , vol.113 , pp. 6411-6418
    • Garzon, R.1    Liu, S.2    Fabbri, M.3    Liu, Z.4    Heaphy, C.E.5    Callegari, E.6    Schwind, S.7    Pang, J.8    Yu, J.9    Muthusamy, N.10
  • 61
    • 0021950948 scopus 로고
    • Hypomethylation of DNA from benign and malignant human colon neoplasms
    • Goelz S.E., Vogelstein B., Hamilton S.R., Feinberg A.P. Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 1985, 228:187-190.
    • (1985) Science , vol.228 , pp. 187-190
    • Goelz, S.E.1    Vogelstein, B.2    Hamilton, S.R.3    Feinberg, A.P.4
  • 63
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • Greger V., Passarge E., Höpping W., Messmer E., Horsthemke B. Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 1989, 83:155-158.
    • (1989) Hum. Genet. , vol.83 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Höpping, W.3    Messmer, E.4    Horsthemke, B.5
  • 64
    • 0034326284 scopus 로고    scopus 로고
    • Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes
    • Grunau C., Hindermann W., Rosenthal A. Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes. Hum. Mol. Genet. 2000, 9:2651-2663.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2651-2663
    • Grunau, C.1    Hindermann, W.2    Rosenthal, A.3
  • 66
    • 0037310198 scopus 로고    scopus 로고
    • Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma
    • Gupta A., Godwin A.K., Vanderveer L., Lu A., Liu J. Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma. Cancer Res. 2003, 63:664-673.
    • (2003) Cancer Res. , vol.63 , pp. 664-673
    • Gupta, A.1    Godwin, A.K.2    Vanderveer, L.3    Lu, A.4    Liu, J.5
  • 68
    • 2342437315 scopus 로고    scopus 로고
    • Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells
    • Hattori N., Nishino K., Ko Y.G., Hattori N., Ohgane J., Tanaka S., Shiota K. Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells. J. Biol. Chem. 2004, 279:17063-17069.
    • (2004) J. Biol. Chem. , vol.279 , pp. 17063-17069
    • Hattori, N.1    Nishino, K.2    Ko, Y.G.3    Hattori, N.4    Ohgane, J.5    Tanaka, S.6    Shiota, K.7
  • 71
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: small RNAs with a big role in gene regulation
    • He L., Hannon G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 2004, 5:522-531.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 72
    • 69449092535 scopus 로고    scopus 로고
    • Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals
    • Henckel A., Nakabayashi K., Sanz L.A., Feil R., Hata K., Arnaud P. Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals. Hum. Mol. Genet. 2009, 18:3375-3383.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 3375-3383
    • Henckel, A.1    Nakabayashi, K.2    Sanz, L.A.3    Feil, R.4    Hata, K.5    Arnaud, P.6
  • 73
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G., Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 2003, 349:2042-2054.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 77
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • Huangfu D., Maehr R., Guo W., Eijkelenboom A., Snitow M., Chen A.E., Melton D.A. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat. Biotechnol. 2008, 26:795-797.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3    Eijkelenboom, A.4    Snitow, M.5    Chen, A.E.6    Melton, D.A.7
  • 78
    • 0031439397 scopus 로고    scopus 로고
    • Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13)
    • Ida K., Kitabayashi I., Taki T., Taniwaki M., Noro K., Yamamoto M., Ohki M., Hayashi Y. Adenoviral E1A-associated protein p300 is involved in acute myeloid leukemia with t(11;22)(q23;q13). Blood 1997, 90:4699-4704.
    • (1997) Blood , vol.90 , pp. 4699-4704
    • Ida, K.1    Kitabayashi, I.2    Taki, T.3    Taniwaki, M.4    Noro, K.5    Yamamoto, M.6    Ohki, M.7    Hayashi, Y.8
  • 80
    • 0035878329 scopus 로고    scopus 로고
    • CpG island of rat sphingosine kinase-1 gene: tissue-dependent DNA methylation status and multiple alternative first exons
    • Imamura T., Ohgane J., Ito S., Ogawa T., Hattori N., Tanaka S., Shiota K. CpG island of rat sphingosine kinase-1 gene: tissue-dependent DNA methylation status and multiple alternative first exons. Genomics 2001, 76:117-125.
    • (2001) Genomics , vol.76 , pp. 117-125
    • Imamura, T.1    Ohgane, J.2    Ito, S.3    Ogawa, T.4    Hattori, N.5    Tanaka, S.6    Shiota, K.7
  • 81
    • 0842320994 scopus 로고    scopus 로고
    • A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability
    • Ionov Y., Matsui S., Cowell J.K. A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability. Proc. Natl. Acad. Sci. USA 2004, 101:1273-1278.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 1273-1278
    • Ionov, Y.1    Matsui, S.2    Cowell, J.K.3
  • 83
    • 0035328527 scopus 로고    scopus 로고
    • Accelerated age-related CpG island methylation in ulcerative colitis
    • Issa J.P., Ahuja N., Toyota M., Bronner M.P., Brentnall T.A. Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res. 2001, 61:3573-3577.
    • (2001) Cancer Res. , vol.61 , pp. 3573-3577
    • Issa, J.P.1    Ahuja, N.2    Toyota, M.3    Bronner, M.P.4    Brentnall, T.A.5
  • 84
    • 33646826162 scopus 로고    scopus 로고
    • Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C
    • Italiano A., Attias R., Aurias A., Pérot G., Burel-Vandenbos F., Otto J., Venissac N., Pedeutour F. Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C. Cancer Genet. Cytogenet. 2006, 167:122-130.
    • (2006) Cancer Genet. Cytogenet. , vol.167 , pp. 122-130
    • Italiano, A.1    Attias, R.2    Aurias, A.3    Pérot, G.4    Burel-Vandenbos, F.5    Otto, J.6    Venissac, N.7    Pedeutour, F.8
  • 85
    • 70949097382 scopus 로고    scopus 로고
    • Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation
    • Jacinto F.V., Ballestar E., Esteller M. Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation. Oncogene 2009, 28:4212-4224.
    • (2009) Oncogene , vol.28 , pp. 4212-4224
    • Jacinto, F.V.1    Ballestar, E.2    Esteller, M.3
  • 87
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones P.A., Baylin S.B. The epigenomics of cancer. Cell 2007, 128:683-692.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 88
    • 72849140654 scopus 로고    scopus 로고
    • Chromatin mechanisms in genomic imprinting
    • Kacem S., Feil R. Chromatin mechanisms in genomic imprinting. Mamm. Genome 2009, 20:544-556.
    • (2009) Mamm. Genome , vol.20 , pp. 544-556
    • Kacem, S.1    Feil, R.2
  • 89
    • 33845762289 scopus 로고    scopus 로고
    • Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
    • Kahl P., Gullotti L., Heukamp L.C., Wolf S., Friedrichs N., Vorreuther R., Solleder G., Bastian P.J., Ellinger J., Metzger E., et al. Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res. 2006, 66:11341-11347.
    • (2006) Cancer Res. , vol.66 , pp. 11341-11347
    • Kahl, P.1    Gullotti, L.2    Heukamp, L.C.3    Wolf, S.4    Friedrichs, N.5    Vorreuther, R.6    Solleder, G.7    Bastian, P.J.8    Ellinger, J.9    Metzger, E.10
  • 91
    • 25444475765 scopus 로고    scopus 로고
    • Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells
    • Karpf A.R., Matsui S. Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells. Cancer Res. 2005, 65:8635-8639.
    • (2005) Cancer Res. , vol.65 , pp. 8635-8639
    • Karpf, A.R.1    Matsui, S.2
  • 92
    • 33846216922 scopus 로고    scopus 로고
    • Maspin: the new frontier
    • Khalkhali-Ellis Z. Maspin: the new frontier. Clin. Cancer Res. 2006, 12:7279-7283.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 7279-7283
    • Khalkhali-Ellis, Z.1
  • 93
    • 34247368534 scopus 로고    scopus 로고
    • Epigenetics in development
    • Kiefer J.C. Epigenetics in development. Dev. Dyn. 2007, 236:1144-1156.
    • (2007) Dev. Dyn. , vol.236 , pp. 1144-1156
    • Kiefer, J.C.1
  • 94
    • 55949130820 scopus 로고    scopus 로고
    • Epigenetics of beta-globin gene regulation
    • Kiefer C.M., Hou C., Little J.A., Dean A. Epigenetics of beta-globin gene regulation. Mutat. Res. 2008, 647:68-76.
    • (2008) Mutat. Res. , vol.647 , pp. 68-76
    • Kiefer, C.M.1    Hou, C.2    Little, J.A.3    Dean, A.4
  • 97
    • 0033765496 scopus 로고    scopus 로고
    • Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis-A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma
    • Kondo Y., Kanai Y., Sakamoto M., Mizokami M., Ueda R., Hirohashi S. Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis-A comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology 2000, 32:970-979.
    • (2000) Hepatology , vol.32 , pp. 970-979
    • Kondo, Y.1    Kanai, Y.2    Sakamoto, M.3    Mizokami, M.4    Ueda, R.5    Hirohashi, S.6
  • 98
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 2007, 128:693-705.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 99
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • Kozaki K., Imoto I., Mogi S., Omura K., Inazawa J. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res. 2008, 68:2094-2105.
    • (2008) Cancer Res. , vol.68 , pp. 2094-2105
    • Kozaki, K.1    Imoto, I.2    Mogi, S.3    Omura, K.4    Inazawa, J.5
  • 101
    • 38049134281 scopus 로고    scopus 로고
    • Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival
    • Li H., Ma X., Wang J., Koontz J., Nucci M., Sklar J. Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. Proc. Natl. Acad. Sci. USA 2007, 104:20001-20006.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 20001-20006
    • Li, H.1    Ma, X.2    Wang, J.3    Koontz, J.4    Nucci, M.5    Sklar, J.6
  • 103
    • 77950867183 scopus 로고    scopus 로고
    • Epigenetic regulation of oligodendrocyte identity
    • Liu J., Casaccia P. Epigenetic regulation of oligodendrocyte identity. Trends Neurosci. 2010, 33:193-201.
    • (2010) Trends Neurosci. , vol.33 , pp. 193-201
    • Liu, J.1    Casaccia, P.2
  • 104
    • 72449186524 scopus 로고    scopus 로고
    • Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
    • Liu G., Bollig-Fischer A., Kreike B., van de Vijver M.J., Abrams J., Ethier S.P., Yang Z.Q. Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer. Oncogene 2009, 28:4491-4500.
    • (2009) Oncogene , vol.28 , pp. 4491-4500
    • Liu, G.1    Bollig-Fischer, A.2    Kreike, B.3    van de Vijver, M.J.4    Abrams, J.5    Ethier, S.P.6    Yang, Z.Q.7
  • 111
    • 61349113967 scopus 로고    scopus 로고
    • Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle
    • Mishra B.P., Ansari K.I., Mandal S.S. Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle. FEBS J. 2009, 276:1629-1640.
    • (2009) FEBS J. , vol.276 , pp. 1629-1640
    • Mishra, B.P.1    Ansari, K.I.2    Mandal, S.S.3
  • 112
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
    • Mohn F., Weber M., Rebhan M., Roloff T.C., Richter J., Stadler M.B., Bibel M., Schübeler D. Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol. Cell 2008, 30:755-766.
    • (2008) Mol. Cell , vol.30 , pp. 755-766
    • Mohn, F.1    Weber, M.2    Rebhan, M.3    Roloff, T.C.4    Richter, J.5    Stadler, M.B.6    Bibel, M.7    Schübeler, D.8
  • 116
    • 76649145629 scopus 로고    scopus 로고
    • Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells
    • Niwa T., Tsukamoto T., Toyoda T., Mori A., Tanaka H., Maekita T., Ichinose M., Tatematsu M., Ushijima T. Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res. 2010, 70:1430-1440.
    • (2010) Cancer Res. , vol.70 , pp. 1430-1440
    • Niwa, T.1    Tsukamoto, T.2    Toyoda, T.3    Mori, A.4    Tanaka, H.5    Maekita, T.6    Ichinose, M.7    Tatematsu, M.8    Ushijima, T.9
  • 119
  • 120
    • 0034803236 scopus 로고    scopus 로고
    • A novel mutation lacking the bromodomain of the transcriptional coactivator p300 in the SiHa cervical carcinoma cell line
    • Ohshima T., Suganuma T., Ikeda M. A novel mutation lacking the bromodomain of the transcriptional coactivator p300 in the SiHa cervical carcinoma cell line. Biochem. Biophys. Res. Commun. 2001, 281:569-575.
    • (2001) Biochem. Biophys. Res. Commun. , vol.281 , pp. 569-575
    • Ohshima, T.1    Suganuma, T.2    Ikeda, M.3
  • 126
    • 0037226714 scopus 로고    scopus 로고
    • Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13)
    • Panagopoulos I., Isaksson M., Lindvall C., Hagemeijer A., Mitelman F., Johansson B. Genomic characterization of MOZ/CBP and CBP/MOZ chimeras in acute myeloid leukemia suggests the involvement of a damage-repair mechanism in the origin of the t(8;16)(p11;p13). Genes Chromosomes Cancer 2003, 36:90-98.
    • (2003) Genes Chromosomes Cancer , vol.36 , pp. 90-98
    • Panagopoulos, I.1    Isaksson, M.2    Lindvall, C.3    Hagemeijer, A.4    Mitelman, F.5    Johansson, B.6
  • 127
    • 49649125809 scopus 로고    scopus 로고
    • An endometrial stromal sarcoma cell line with the JAZF1/PHF1 chimera
    • Panagopoulos I., Mertens F., Griffin C.A. An endometrial stromal sarcoma cell line with the JAZF1/PHF1 chimera. Cancer Genet. Cytogenet. 2008, 185:74-77.
    • (2008) Cancer Genet. Cytogenet. , vol.185 , pp. 74-77
    • Panagopoulos, I.1    Mertens, F.2    Griffin, C.A.3
  • 128
  • 131
    • 0036803978 scopus 로고    scopus 로고
    • The prospective role of abnormal methyl metabolism in cadmium toxicity
    • Poirier L.A., Vlasova T.I. The prospective role of abnormal methyl metabolism in cadmium toxicity. Environ. Health Perspect. 2002, 110(Suppl 5):793-795.
    • (2002) Environ. Health Perspect. , vol.110 , Issue.SUPPL. 5 , pp. 793-795
    • Poirier, L.A.1    Vlasova, T.I.2
  • 132
    • 33644965054 scopus 로고    scopus 로고
    • 5′ CpG island methylation analysis identifies the MAGE-A1 and MAGE-A3 genes as potential markers of HCC
    • Qiu G., Fang J., He Y. 5′ CpG island methylation analysis identifies the MAGE-A1 and MAGE-A3 genes as potential markers of HCC. Clin. Biochem. 2006, 39:259-266.
    • (2006) Clin. Biochem. , vol.39 , pp. 259-266
    • Qiu, G.1    Fang, J.2    He, Y.3
  • 134
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007, 447:425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 135
    • 17744391429 scopus 로고    scopus 로고
    • Co-evolution of X-chromosome inactivation and imprinting in mammals
    • Reik W., Lewis A. Co-evolution of X-chromosome inactivation and imprinting in mammals. Nat. Rev. Genet. 2005, 6:403-410.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 403-410
    • Reik, W.1    Lewis, A.2
  • 136
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W., Dean W., Walter J. Epigenetic reprogramming in mammalian development. Science 2001, 293:1089-1093.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 137
    • 0035839106 scopus 로고    scopus 로고
    • Nuclear cloning and epigenetic reprogramming of the genome
    • Rideout W.M., Eggan K., Jaenisch R. Nuclear cloning and epigenetic reprogramming of the genome. Science 2001, 293:1093-1098.
    • (2001) Science , vol.293 , pp. 1093-1098
    • Rideout, W.M.1    Eggan, K.2    Jaenisch, R.3
  • 138
    • 64049112779 scopus 로고    scopus 로고
    • Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes
    • Robert I., Aussems M., Keutgens A., Zhang X., Hennuy B., Viatour P., Vanstraelen G., Merville M.P., Chapelle J.P., de Leval L., et al. Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes. Oncogene 2009, 28:1626-1638.
    • (2009) Oncogene , vol.28 , pp. 1626-1638
    • Robert, I.1    Aussems, M.2    Keutgens, A.3    Zhang, X.4    Hennuy, B.5    Viatour, P.6    Vanstraelen, G.7    Merville, M.P.8    Chapelle, J.P.9    de Leval, L.10
  • 139
    • 33750488431 scopus 로고    scopus 로고
    • The genomic landscape of histone modifications in human T cells
    • Roh T.Y., Cuddapah S., Cui K., Zhao K. The genomic landscape of histone modifications in human T cells. Proc. Natl. Acad. Sci. USA 2006, 103:15782-15787.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15782-15787
    • Roh, T.Y.1    Cuddapah, S.2    Cui, K.3    Zhao, K.4
  • 140
    • 58649114520 scopus 로고    scopus 로고
    • Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest
    • Rokudai S., Aikawa Y., Tagata Y., Tsuchida N., Taya Y., Kitabayashi I. Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest. J. Biol. Chem. 2009, 284:237-244.
    • (2009) J. Biol. Chem. , vol.284 , pp. 237-244
    • Rokudai, S.1    Aikawa, Y.2    Tagata, Y.3    Tsuchida, N.4    Taya, Y.5    Kitabayashi, I.6
  • 142
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells
    • Saito Y., Liang G., Egger G., Friedman J.M., Chuang J.C., Coetzee G.A., Jones P.A. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006, 9:435-443.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3    Friedman, J.M.4    Chuang, J.C.5    Coetzee, G.A.6    Jones, P.A.7
  • 145
    • 1542636969 scopus 로고    scopus 로고
    • Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling
    • Sato N., Fukushima N., Matsubayashi H., Goggins M. Identification of maspin and S100P as novel hypomethylation targets in pancreatic cancer using global gene expression profiling. Oncogene 2004, 23:1531-1538.
    • (2004) Oncogene , vol.23 , pp. 1531-1538
    • Sato, N.1    Fukushima, N.2    Matsubayashi, H.3    Goggins, M.4
  • 146
    • 34547476585 scopus 로고    scopus 로고
    • Global, comparative analysis of tissue-specific promoter CpG methylation
    • Schilling E., Rehli M. Global, comparative analysis of tissue-specific promoter CpG methylation. Genomics 2007, 90:314-323.
    • (2007) Genomics , vol.90 , pp. 314-323
    • Schilling, E.1    Rehli, M.2
  • 149
    • 33645319220 scopus 로고    scopus 로고
    • L1 retrotransposons in human cancers
    • Schulz W.A. L1 retrotransposons in human cancers. J. Biomed. Biotechnol. 2006, 2006:83672.
    • (2006) J. Biomed. Biotechnol. , vol.2006 , pp. 83672
    • Schulz, W.A.1
  • 150
    • 46749139575 scopus 로고    scopus 로고
    • The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells
    • Scuto A., Kirschbaum M., Kowolik C., Kretzner L., Juhasz A., Atadja P., Pullarkat V., Bhatia R., Forman S., Yen Y., Jove R. The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Blood 2008, 111:5093-5100.
    • (2008) Blood , vol.111 , pp. 5093-5100
    • Scuto, A.1    Kirschbaum, M.2    Kowolik, C.3    Kretzner, L.4    Juhasz, A.5    Atadja, P.6    Pullarkat, V.7    Bhatia, R.8    Forman, S.9    Yen, Y.10    Jove, R.11
  • 151
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • Seligson D.B., Horvath S., Shi T., Yu H., Tze S., Grunstein M., Kurdistani S.K. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 2005, 435:1262-1266.
    • (2005) Nature , vol.435 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3    Yu, H.4    Tze, S.5    Grunstein, M.6    Kurdistani, S.K.7
  • 153
    • 67650657838 scopus 로고    scopus 로고
    • Definition, conservation and epigenetics of housekeeping and tissue-enriched genes
    • She X., Rohl C.A., Castle J.C., Kulkarni A.V., Johnson J.M., Chen R. Definition, conservation and epigenetics of housekeeping and tissue-enriched genes. BMC Genomics 2009, 10:269.
    • (2009) BMC Genomics , vol.10 , pp. 269
    • She, X.1    Rohl, C.A.2    Castle, J.C.3    Kulkarni, A.V.4    Johnson, J.M.5    Chen, R.6
  • 155
    • 54949115497 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
    • Shi Y., Desponts C., Do J.T., Hahm H.S., Schöler H.R., Ding S. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 2008, 3:568-574.
    • (2008) Cell Stem Cell , vol.3 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.T.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 158
    • 0033831298 scopus 로고    scopus 로고
    • Lead as a carcinogen: experimental evidence and mechanisms of action
    • Silbergeld E.K., Waalkes M., Rice J.M. Lead as a carcinogen: experimental evidence and mechanisms of action. Am. J. Ind. Med. 2000, 38:316-323.
    • (2000) Am. J. Ind. Med. , vol.38 , pp. 316-323
    • Silbergeld, E.K.1    Waalkes, M.2    Rice, J.M.3
  • 160
    • 2442443111 scopus 로고    scopus 로고
    • Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene
    • Strathdee G., Davies B.R., Vass J.K., Siddiqui N., Brown R. Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene. Carcinogenesis 2004, 25:693-701.
    • (2004) Carcinogenesis , vol.25 , pp. 693-701
    • Strathdee, G.1    Davies, B.R.2    Vass, J.K.3    Siddiqui, N.4    Brown, R.5
  • 161
    • 33847316144 scopus 로고    scopus 로고
    • HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemia
    • Strathdee G., Sim A., Soutar R., Holyoake T.L., Brown R. HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemia. Carcinogenesis 2007, 28:299-309.
    • (2007) Carcinogenesis , vol.28 , pp. 299-309
    • Strathdee, G.1    Sim, A.2    Soutar, R.3    Holyoake, T.L.4    Brown, R.5
  • 163
    • 0035231832 scopus 로고    scopus 로고
    • Novel human HALR (MLL3) gene encodes a protein homologous to ALR and to ALL-1 involved in leukemia, and maps to chromosome 7q36 associated with leukemia and developmental defects
    • Tan Y.C., Chow V.T. Novel human HALR (MLL3) gene encodes a protein homologous to ALR and to ALL-1 involved in leukemia, and maps to chromosome 7q36 associated with leukemia and developmental defects. Cancer Detect. Prev. 2001, 25:454-469.
    • (2001) Cancer Detect. Prev. , vol.25 , pp. 454-469
    • Tan, Y.C.1    Chow, V.T.2
  • 164
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • Toyota M., Suzuki H., Sasaki Y., Maruyama R., Imai K., Shinomura Y., Tokino T. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 2008, 68:4123-4132.
    • (2008) Cancer Res. , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3    Maruyama, R.4    Imai, K.5    Shinomura, Y.6    Tokino, T.7
  • 165
    • 74549161822 scopus 로고    scopus 로고
    • Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells
    • Tsai K.W., Kao H.W., Chen H.C., Chen S.J., Lin W.C. Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells. Epigenetics 2009, 4:587-592.
    • (2009) Epigenetics , vol.4 , pp. 587-592
    • Tsai, K.W.1    Kao, H.W.2    Chen, H.C.3    Chen, S.J.4    Lin, W.C.5
  • 166
    • 33747871839 scopus 로고    scopus 로고
    • Chromosome-wide, allele-specific analysis of the histone code on the human X chromosome
    • Valley C.M., Pertz L.M., Balakumaran B.S., Willard H.F. Chromosome-wide, allele-specific analysis of the histone code on the human X chromosome. Hum. Mol. Genet. 2006, 15:2335-2347.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 2335-2347
    • Valley, C.M.1    Pertz, L.M.2    Balakumaran, B.S.3    Willard, H.F.4
  • 169
    • 74049144071 scopus 로고    scopus 로고
    • CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain
    • Wang J., Weaver I.C., Gauthier-Fisher A., Wang H., He L., Yeomans J., Wondisford F., Kaplan D.R., Miller F.D. CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain. Dev. Cell 2010, 18:114-125.
    • (2010) Dev. Cell , vol.18 , pp. 114-125
    • Wang, J.1    Weaver, I.C.2    Gauthier-Fisher, A.3    Wang, H.4    He, L.5    Yeomans, J.6    Wondisford, F.7    Kaplan, D.R.8    Miller, F.D.9
  • 170
    • 33144488275 scopus 로고    scopus 로고
    • Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus
    • Waterland R.A., Lin J.R., Smith C.A., Jirtle R.L. Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus. Hum. Mol. Genet. 2006, 15:705-716.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 705-716
    • Waterland, R.A.1    Lin, J.R.2    Smith, C.A.3    Jirtle, R.L.4
  • 171
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M., Hellmann I., Stadler M.B., Ramos L., Pääbo S., Rebhan M., Schübeler D. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet. 2007, 39:457-466.
    • (2007) Nat. Genet. , vol.39 , pp. 457-466
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3    Ramos, L.4    Pääbo, S.5    Rebhan, M.6    Schübeler, D.7
  • 172
    • 1042266669 scopus 로고    scopus 로고
    • Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin
    • Wei Y.D., Tepperman K., Huang M.Y., Sartor M.A., Puga A. Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin. J. Biol. Chem. 2004, 279:4110-4119.
    • (2004) J. Biol. Chem. , vol.279 , pp. 4110-4119
    • Wei, Y.D.1    Tepperman, K.2    Huang, M.Y.3    Sartor, M.A.4    Puga, A.5
  • 173
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • Wei G., Wei L., Zhu J., Zang C., Hu-Li J., Yao Z., Cui K., Kanno Y., Roh T.Y., Watford W.T., et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 2009, 30:155-167.
    • (2009) Immunity , vol.30 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3    Zang, C.4    Hu-Li, J.5    Yao, Z.6    Cui, K.7    Kanno, Y.8    Roh, T.Y.9    Watford, W.T.10
  • 176
    • 77349089525 scopus 로고    scopus 로고
    • Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation
    • Wu Y., Alvarez M., Slamon D.J., Koeffler P., Vadgama J.V. Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. BMC Cancer 2010, 10:32.
    • (2010) BMC Cancer , vol.10 , pp. 32
    • Wu, Y.1    Alvarez, M.2    Slamon, D.J.3    Koeffler, P.4    Vadgama, J.V.5
  • 178
    • 2342599619 scopus 로고    scopus 로고
    • The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
    • Yang X.J. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic Acids Res. 2004, 32:959-976.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 959-976
    • Yang, X.J.1
  • 179
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • Zhang B., Pan X., Cobb G.P., Anderson T.A. microRNAs as oncogenes and tumor suppressors. Dev. Biol. 2007, 302:1-12.
    • (2007) Dev. Biol. , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 180
    • 71349083845 scopus 로고    scopus 로고
    • 5-Azacytidine facilitates osteogenic gene expression and differentiation of mesenchymal stem cells by alteration in DNA methylation
    • Jun
    • Zhou G.S., Zhang X.L., Wu J.P., Zhang R.P., Xiang L.X., Dai L.C., Shao J.Z. 5-Azacytidine facilitates osteogenic gene expression and differentiation of mesenchymal stem cells by alteration in DNA methylation. Cytotechnology 2009, (Jun):26.
    • (2009) Cytotechnology , pp. 26
    • Zhou, G.S.1    Zhang, X.L.2    Wu, J.P.3    Zhang, R.P.4    Xiang, L.X.5    Dai, L.C.6    Shao, J.Z.7
  • 181
    • 68349125550 scopus 로고    scopus 로고
    • Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma
    • Zhu C., Qin Y.R., Xie D., Chua D.T., Fung J.M., Chen L., Fu L., Hu L., Guan X.Y. Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma. Oncogene 2009, 28:2821-2828.
    • (2009) Oncogene , vol.28 , pp. 2821-2828
    • Zhu, C.1    Qin, Y.R.2    Xie, D.3    Chua, D.T.4    Fung, J.M.5    Chen, L.6    Fu, L.7    Hu, L.8    Guan, X.Y.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.