메뉴 건너뛰기




Volumn 693, Issue 1-2, 2010, Pages 53-60

Epigenomics of human colon cancer

Author keywords

Colon cancer; DNA methylation; Epigenomics; Genome wide

Indexed keywords

CADHERIN; CYCLIN A1; CYCLOOXYGENASE 2; DEATH ASSOCIATED PROTEIN KINASE; DICKKOPF 1 PROTEIN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; FOLLISTATIN; HOMEODOMAIN PROTEIN; MEMBRANE PROTEIN; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; RETINOL BINDING PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SODIUM GLUCOSE COTRANSPORTER 8; SOMATOMEDIN; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 5; UNCLASSIFIED DRUG;

EID: 78049443505     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2010.07.007     Document Type: Review
Times cited : (51)

References (82)
  • 2
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • Fraga M.F., Ballestar E., Villar-Garea A., et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nature Genetics 2005, 37(4):391-400.
    • (2005) Nature Genetics , vol.37 , Issue.4 , pp. 391-400
    • Fraga, M.F.1    Ballestar, E.2    Villar-Garea, A.3
  • 3
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • Seligson D.B., Horvath S., Shi T., et al. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 2005, 435(7046):1262-1266.
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1    Horvath, S.2    Shi, T.3
  • 4
    • 72949093641 scopus 로고    scopus 로고
    • MicroRNAs as potential cancer therapeutics
    • Trang P., Weidhaas J.B., Slack F.J. MicroRNAs as potential cancer therapeutics. Oncogene 2008, 27(Suppl. 2):S52-S57.
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 2
    • Trang, P.1    Weidhaas, J.B.2    Slack, F.J.3
  • 5
    • 18644383745 scopus 로고    scopus 로고
    • Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer
    • Wagner K.J., Cooper W.N., Grundy R.G., et al. Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer. Oncogene 2002, 21(47):7277-7282.
    • (2002) Oncogene , vol.21 , Issue.47 , pp. 7277-7282
    • Wagner, K.J.1    Cooper, W.N.2    Grundy, R.G.3
  • 6
    • 28544450494 scopus 로고    scopus 로고
    • Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors
    • Alazzouzi H., Davalos V., Kokko A., et al. Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors. Cancer Research 2005, 65(22):10170-10173.
    • (2005) Cancer Research , vol.65 , Issue.22 , pp. 10170-10173
    • Alazzouzi, H.1    Davalos, V.2    Kokko, A.3
  • 7
    • 0028875205 scopus 로고
    • Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M., Bender C.M., Yang A.S., et al. Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Research 1995, 55(20):4531-4535.
    • (1995) Cancer Research , vol.55 , Issue.20 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3
  • 8
    • 2342504508 scopus 로고    scopus 로고
    • Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers
    • Goel A., Arnold C.N., Niedzwiecki D., et al. Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Research 2004, 64(9):3014-3021.
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3014-3021
    • Goel, A.1    Arnold, C.N.2    Niedzwiecki, D.3
  • 9
    • 18244388241 scopus 로고    scopus 로고
    • DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
    • Esteller M., Fraga M.F., Guo M., et al. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Human Molecular Genetics 2001, 10(26):3001-3007.
    • (2001) Human Molecular Genetics , vol.10 , Issue.26 , pp. 3001-3007
    • Esteller, M.1    Fraga, M.F.2    Guo, M.3
  • 10
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg A.P., Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983, 301(5895):89-92.
    • (1983) Nature , vol.301 , Issue.5895 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 13
    • 0037436509 scopus 로고    scopus 로고
    • Loss of IGF2 imprinting: a potential marker of colorectal cancer risk
    • Cui H., Cruz-Correa M., Giardiello F.M., et al. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 2003, 299(5613):1753-1755.
    • (2003) Science , vol.299 , Issue.5613 , pp. 1753-1755
    • Cui, H.1    Cruz-Correa, M.2    Giardiello, F.M.3
  • 14
    • 1542318319 scopus 로고    scopus 로고
    • Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women
    • Woodson K., Flood A., Green L., et al. Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women. Journal of the National Cancer Institute 2004, 96(5):407-410.
    • (2004) Journal of the National Cancer Institute , vol.96 , Issue.5 , pp. 407-410
    • Woodson, K.1    Flood, A.2    Green, L.3
  • 15
    • 33645777446 scopus 로고    scopus 로고
    • CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure
    • Bock C., Paulsen M., Tierling S., Mikeska T., Lengauer T., Walter J. CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure. PLoS Genetics 2006, 2(3):e26.
    • (2006) PLoS Genetics , vol.2 , Issue.3
    • Bock, C.1    Paulsen, M.2    Tierling, S.3    Mikeska, T.4    Lengauer, T.5    Walter, J.6
  • 16
    • 33646120548 scopus 로고    scopus 로고
    • DNA motifs associated with aberrant CpG island methylation
    • Feltus F.A., Lee E.K., Costello J.F., Plass C., Vertino P.M. DNA motifs associated with aberrant CpG island methylation. Genomics 2006, 87(5):572-579.
    • (2006) Genomics , vol.87 , Issue.5 , pp. 572-579
    • Feltus, F.A.1    Lee, E.K.2    Costello, J.F.3    Plass, C.4    Vertino, P.M.5
  • 18
    • 0041382819 scopus 로고    scopus 로고
    • Genetics supersedes epigenetics in colon cancer phenotype
    • Yamashita K., Dai T., Dai Y., Yamamoto F., Perucho M. Genetics supersedes epigenetics in colon cancer phenotype. Cancer Cell 2003, 4(2):121-131.
    • (2003) Cancer Cell , vol.4 , Issue.2 , pp. 121-131
    • Yamashita, K.1    Dai, T.2    Dai, Y.3    Yamamoto, F.4    Perucho, M.5
  • 19
    • 20844453068 scopus 로고    scopus 로고
    • Colorectal cancer " methylator phenotype": fact or artifact?
    • Anacleto C., Leopoldino A.M., Rossi B., et al. Colorectal cancer " methylator phenotype": fact or artifact?. Neoplasia (New York, NY) 2005, 7(4):331-335.
    • (2005) Neoplasia (New York, NY) , vol.7 , Issue.4 , pp. 331-335
    • Anacleto, C.1    Leopoldino, A.M.2    Rossi, B.3
  • 20
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J.G., Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. The New England Journal of Medicine 2003, 349(21):2042-2054.
    • (2003) The New England Journal of Medicine , vol.349 , Issue.21 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 21
    • 0037096946 scopus 로고    scopus 로고
    • Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas
    • Toyooka S., Toyooka K.O., Harada K., et al. Aberrant methylation of the CDH13 (H-cadherin) promoter region in colorectal cancers and adenomas. Cancer Research 2002, 62(12):3382-3386.
    • (2002) Cancer Research , vol.62 , Issue.12 , pp. 3382-3386
    • Toyooka, S.1    Toyooka, K.O.2    Harada, K.3
  • 22
    • 20144372468 scopus 로고    scopus 로고
    • CpG island methylation in aberrant crypt foci and cancers from the same patients
    • Luo L., Chen W.D., Pretlow T.P. CpG island methylation in aberrant crypt foci and cancers from the same patients. International Journal of Cancer 2005, 115(5):747-751.
    • (2005) International Journal of Cancer , vol.115 , Issue.5 , pp. 747-751
    • Luo, L.1    Chen, W.D.2    Pretlow, T.P.3
  • 23
    • 33745812020 scopus 로고    scopus 로고
    • DAPK promotor methylation is an early event in colorectal carcinogenesis
    • Mittag F., Kuester D., Vieth M., et al. DAPK promotor methylation is an early event in colorectal carcinogenesis. Cancer Letters 2006, 240(1):69-75.
    • (2006) Cancer Letters , vol.240 , Issue.1 , pp. 69-75
    • Mittag, F.1    Kuester, D.2    Vieth, M.3
  • 24
    • 11144356102 scopus 로고    scopus 로고
    • Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition
    • Cruz-Correa M., Cui H., Giardiello F.M., et al. Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. Gastroenterology 2004, 126(4):964-970.
    • (2004) Gastroenterology , vol.126 , Issue.4 , pp. 964-970
    • Cruz-Correa, M.1    Cui, H.2    Giardiello, F.M.3
  • 25
    • 33644686386 scopus 로고    scopus 로고
    • Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers
    • Ebert M.P., Mooney S.H., Tonnes-Priddy L., et al. Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. Neoplasia (New York, NY) 2005, 7(8):771-778.
    • (2005) Neoplasia (New York, NY) , vol.7 , Issue.8 , pp. 771-778
    • Ebert, M.P.1    Mooney, S.H.2    Tonnes-Priddy, L.3
  • 26
    • 70349656779 scopus 로고    scopus 로고
    • Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer
    • Lee B.B., Lee E.J., Jung E.H., et al. Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer. Clinical Cancer Research 2009, 15(19):6185-6191.
    • (2009) Clinical Cancer Research , vol.15 , Issue.19 , pp. 6185-6191
    • Lee, B.B.1    Lee, E.J.2    Jung, E.H.3
  • 27
    • 37549066863 scopus 로고    scopus 로고
    • Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells
    • Jacinto F.V., Ballestar E., Ropero S., Esteller M. Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells. Cancer Research 2007, 67(24):11481-11486.
    • (2007) Cancer Research , vol.67 , Issue.24 , pp. 11481-11486
    • Jacinto, F.V.1    Ballestar, E.2    Ropero, S.3    Esteller, M.4
  • 28
    • 0041779528 scopus 로고    scopus 로고
    • Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases
    • Paz M.F., Wei S., Cigudosa J.C., et al. Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. Human Molecular Genetics 2003, 12(17):2209-2219.
    • (2003) Human Molecular Genetics , vol.12 , Issue.17 , pp. 2209-2219
    • Paz, M.F.1    Wei, S.2    Cigudosa, J.C.3
  • 29
    • 12144291274 scopus 로고    scopus 로고
    • Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
    • Suzuki H., Watkins D.N., Jair K.W., et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nature Genetics 2004, 36(4):417-422.
    • (2004) Nature Genetics , vol.36 , Issue.4 , pp. 417-422
    • Suzuki, H.1    Watkins, D.N.2    Jair, K.W.3
  • 30
    • 0034662626 scopus 로고    scopus 로고
    • Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer
    • Esteller M., Sparks A., Toyota M., et al. Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer. Cancer Research 2000, 60(16):4366-4371.
    • (2000) Cancer Research , vol.60 , Issue.16 , pp. 4366-4371
    • Esteller, M.1    Sparks, A.2    Toyota, M.3
  • 32
    • 9244242523 scopus 로고    scopus 로고
    • Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis
    • Xu X.L., Yu J., Zhang H.Y., et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World Journal of Gastroenterology 2004, 10(23):3441-3454.
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.23 , pp. 3441-3454
    • Xu, X.L.1    Yu, J.2    Zhang, H.Y.3
  • 33
    • 67449128445 scopus 로고    scopus 로고
    • GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer
    • Hellebrekers D.M., Lentjes M.H., van den Bosch S.M., et al. GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer. Clinical Cancer Research 2009, 15(12):3990-3997.
    • (2009) Clinical Cancer Research , vol.15 , Issue.12 , pp. 3990-3997
    • Hellebrekers, D.M.1    Lentjes, M.H.2    van den Bosch, S.M.3
  • 34
    • 0029014425 scopus 로고
    • P53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
    • Wales M.M., Biel M.A., el Deiry W., et al. p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nature Medicine 1995, 1(6):570-577.
    • (1995) Nature Medicine , vol.1 , Issue.6 , pp. 570-577
    • Wales, M.M.1    Biel, M.A.2    el Deiry, W.3
  • 35
    • 0037442753 scopus 로고    scopus 로고
    • Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer
    • Ricciardiello L., Goel A., Mantovani V., et al. Frequent loss of hMLH1 by promoter hypermethylation leads to microsatellite instability in adenomatous polyps of patients with a single first-degree member affected by colon cancer. Cancer Research 2003, 63(4):787-792.
    • (2003) Cancer Research , vol.63 , Issue.4 , pp. 787-792
    • Ricciardiello, L.1    Goel, A.2    Mantovani, V.3
  • 37
    • 0036161851 scopus 로고    scopus 로고
    • Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability
    • Yamamoto H., Min Y., Itoh F., et al. Differential involvement of the hypermethylator phenotype in hereditary and sporadic colorectal cancers with high-frequency microsatellite instability. Genes, Chromosomes & Cancer 2002, 33(3):322-325.
    • (2002) Genes, Chromosomes & Cancer , vol.33 , Issue.3 , pp. 322-325
    • Yamamoto, H.1    Min, Y.2    Itoh, F.3
  • 38
    • 43949122576 scopus 로고    scopus 로고
    • The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer
    • Rojas A., Meherem S., Kim Y.H., et al. The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer. International Journal of Cancer 2008, 123(1):14-21.
    • (2008) International Journal of Cancer , vol.123 , Issue.1 , pp. 14-21
    • Rojas, A.1    Meherem, S.2    Kim, Y.H.3
  • 39
    • 33745765883 scopus 로고    scopus 로고
    • Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer
    • Aguilera O., Fraga M.F., Ballestar E., et al. Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer. Oncogene 2006, 25(29):4116-4121.
    • (2006) Oncogene , vol.25 , Issue.29 , pp. 4116-4121
    • Aguilera, O.1    Fraga, M.F.2    Ballestar, E.3
  • 42
    • 0038153876 scopus 로고    scopus 로고
    • SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers
    • Li H., Myeroff L., Smiraglia D., et al. SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers. Proceedings of the National Academy of Sciences of the United States of America 2003, 100(14):8412-8417.
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.14 , pp. 8412-8417
    • Li, H.1    Myeroff, L.2    Smiraglia, D.3
  • 43
    • 0242552587 scopus 로고    scopus 로고
    • GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer
    • Akiyama Y., Watkins N., Suzuki H., et al. GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer. Molecular and Cellular Biology 2003, 23(23):8429-8439.
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.23 , pp. 8429-8439
    • Akiyama, Y.1    Watkins, N.2    Suzuki, H.3
  • 44
    • 34447106125 scopus 로고    scopus 로고
    • Comparative DNA methylation analysis in normal and tumour tissues and in cancer cell lines using differential methylation hybridisation
    • Lewin J., Plum A., Hildmann T., et al. Comparative DNA methylation analysis in normal and tumour tissues and in cancer cell lines using differential methylation hybridisation. The International Journal of Biochemistry & Cell Biology 2007, 39(7-8):1539-1550.
    • (2007) The International Journal of Biochemistry & Cell Biology , vol.39 , Issue.7-8 , pp. 1539-1550
    • Lewin, J.1    Plum, A.2    Hildmann, T.3
  • 45
    • 12744271900 scopus 로고    scopus 로고
    • Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer
    • Frigola J., Sole X., Paz M.F., et al. Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer. Human Molecular Genetics 2005, 14(2):319-326.
    • (2005) Human Molecular Genetics , vol.14 , Issue.2 , pp. 319-326
    • Frigola, J.1    Sole, X.2    Paz, M.F.3
  • 46
    • 18344390653 scopus 로고    scopus 로고
    • DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
    • Rhee I., Bachman K.E., Park B.H., et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002, 416(6880):552-556.
    • (2002) Nature , vol.416 , Issue.6880 , pp. 552-556
    • Rhee, I.1    Bachman, K.E.2    Park, B.H.3
  • 47
    • 33847763576 scopus 로고    scopus 로고
    • Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
    • Lujambio A., Ropero S., Ballestar E., et al. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Research 2007, 67(4):1424-1429.
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1424-1429
    • Lujambio, A.1    Ropero, S.2    Ballestar, E.3
  • 48
    • 33845679095 scopus 로고    scopus 로고
    • ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
    • Lind G.E., Kleivi K., Meling G.I., et al. ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis. Cellular Oncology 2006, 28(5-6):259-272.
    • (2006) Cellular Oncology , vol.28 , Issue.5-6 , pp. 259-272
    • Lind, G.E.1    Kleivi, K.2    Meling, G.I.3
  • 49
    • 0036613250 scopus 로고    scopus 로고
    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    • Suzuki H., Gabrielson E., Chen W., et al. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nature Genetics 2002, 31(2):141-149.
    • (2002) Nature Genetics , vol.31 , Issue.2 , pp. 141-149
    • Suzuki, H.1    Gabrielson, E.2    Chen, W.3
  • 51
    • 33645736546 scopus 로고    scopus 로고
    • PGP9.5 methylation in diffuse-type gastric cancer
    • Yamashita K., Park H.L., Kim M.S., et al. PGP9.5 methylation in diffuse-type gastric cancer. Cancer Research 2006, 66(7):3921-3927.
    • (2006) Cancer Research , vol.66 , Issue.7 , pp. 3921-3927
    • Yamashita, K.1    Park, H.L.2    Kim, M.S.3
  • 52
    • 0012508834 scopus 로고    scopus 로고
    • Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma
    • Yamashita K., Upadhyay S., Osada M., et al. Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma. Cancer Cell 2002, 2(6):485-495.
    • (2002) Cancer Cell , vol.2 , Issue.6 , pp. 485-495
    • Yamashita, K.1    Upadhyay, S.2    Osada, M.3
  • 53
    • 34547824239 scopus 로고    scopus 로고
    • Genome-epigenome interactions in cancer
    • Brena R.M., Costello J.F. Genome-epigenome interactions in cancer. Human Molecular Genetics 2007, 16(Spec No. 1):R96-R105.
    • (2007) Human Molecular Genetics , vol.16 , Issue.SPEC NO. 1
    • Brena, R.M.1    Costello, J.F.2
  • 54
    • 23044514626 scopus 로고    scopus 로고
    • Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
    • Weber M., Davies J.J., Wittig D., et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nature Genetics 2005, 37(8):853-862.
    • (2005) Nature Genetics , vol.37 , Issue.8 , pp. 853-862
    • Weber, M.1    Davies, J.J.2    Wittig, D.3
  • 55
    • 31744433660 scopus 로고    scopus 로고
    • Evidence for an instructive mechanism of de novo methylation in cancer cells
    • Keshet I., Schlesinger Y., Farkash S., et al. Evidence for an instructive mechanism of de novo methylation in cancer cells. Nature Genetics 2006, 38(2):149-153.
    • (2006) Nature Genetics , vol.38 , Issue.2 , pp. 149-153
    • Keshet, I.1    Schlesinger, Y.2    Farkash, S.3
  • 56
    • 0011964662 scopus 로고    scopus 로고
    • Tumour class prediction and discovery by microarray-based DNA methylation analysis
    • Adorjan P., Distler J., Lipscher E., et al. Tumour class prediction and discovery by microarray-based DNA methylation analysis. Nucleic Acids Research 2002, 30(5):e21.
    • (2002) Nucleic Acids Research , vol.30 , Issue.5
    • Adorjan, P.1    Distler, J.2    Lipscher, E.3
  • 57
    • 46949098742 scopus 로고    scopus 로고
    • A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
    • Down T.A., Rakyan V.K., Turner D.J., et al. A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nature Biotechnology 2008, 26(7):779-785.
    • (2008) Nature Biotechnology , vol.26 , Issue.7 , pp. 779-785
    • Down, T.A.1    Rakyan, V.K.2    Turner, D.J.3
  • 58
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nature Reviews 2007, 8(4):286-298.
    • (2007) Nature Reviews , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 62
    • 40749119357 scopus 로고    scopus 로고
    • WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer
    • Ying J., Li H., Yu J., et al. WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer. Clinical Cancer Research 2008, 14(1):55-61.
    • (2008) Clinical Cancer Research , vol.14 , Issue.1 , pp. 55-61
    • Ying, J.1    Li, H.2    Yu, J.3
  • 63
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • Baylin S.B., Ohm J.E. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?. Nature Reviews: Cancer 2006, 6(2):107-116.
    • (2006) Nature Reviews: Cancer , vol.6 , Issue.2 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 66
    • 33947266099 scopus 로고    scopus 로고
    • Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease
    • Model F., Osborn N., Ahlquist D., et al. Identification and validation of colorectal neoplasia-specific methylation markers for accurate classification of disease. Molecular Cancer Research 2007, 5(2):153-163.
    • (2007) Molecular Cancer Research , vol.5 , Issue.2 , pp. 153-163
    • Model, F.1    Osborn, N.2    Ahlquist, D.3
  • 68
    • 0034949862 scopus 로고    scopus 로고
    • In-tube DNA methylation profiling by fluorescence melting curve analysis
    • Worm J., Aggerholm A., Guldberg P. In-tube DNA methylation profiling by fluorescence melting curve analysis. Clinical Chemistry 2001, 47(7):1183-1189.
    • (2001) Clinical Chemistry , vol.47 , Issue.7 , pp. 1183-1189
    • Worm, J.1    Aggerholm, A.2    Guldberg, P.3
  • 69
    • 68149157845 scopus 로고    scopus 로고
    • Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene
    • Candiloro I.L., Mikeska T., Hokland P., Dobrovic A. Rapid analysis of heterogeneously methylated DNA using digital methylation-sensitive high resolution melting: application to the CDKN2B (p15) gene. Epigenetics & Chromatin 2008, 1(1):7.
    • (2008) Epigenetics & Chromatin , vol.1 , Issue.1 , pp. 7
    • Candiloro, I.L.1    Mikeska, T.2    Hokland, P.3    Dobrovic, A.4
  • 70
  • 71
    • 38749150922 scopus 로고    scopus 로고
    • CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci
    • Kawasaki T., Ohnishi M., Nosho K., et al. CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci. Modern Pathology 2008, 21(3):245-255.
    • (2008) Modern Pathology , vol.21 , Issue.3 , pp. 245-255
    • Kawasaki, T.1    Ohnishi, M.2    Nosho, K.3
  • 73
    • 40049096639 scopus 로고    scopus 로고
    • Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening
    • Wang D.R., Tang D. Hypermethylated SFRP2 gene in fecal DNA is a high potential biomarker for colorectal cancer noninvasive screening. World Journal of Gastroenterology 2008, 14(4):524-531.
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.4 , pp. 524-531
    • Wang, D.R.1    Tang, D.2
  • 74
    • 33644649616 scopus 로고    scopus 로고
    • High-throughput DNA methylation profiling using universal bead arrays
    • Bibikova M., Lin Z., Zhou L., et al. High-throughput DNA methylation profiling using universal bead arrays. Genome Research 2006, 16(3):383-393.
    • (2006) Genome Research , vol.16 , Issue.3 , pp. 383-393
    • Bibikova, M.1    Lin, Z.2    Zhou, L.3
  • 77
    • 0036613432 scopus 로고    scopus 로고
    • Role for DNA methylation in the control of cell type specific maspin expression
    • Futscher B.W., Oshiro M.M., Wozniak R.J., et al. Role for DNA methylation in the control of cell type specific maspin expression. Nature Genetics 2002, 31(2):175-179.
    • (2002) Nature Genetics , vol.31 , Issue.2 , pp. 175-179
    • Futscher, B.W.1    Oshiro, M.M.2    Wozniak, R.J.3
  • 78
    • 33751505540 scopus 로고    scopus 로고
    • DNA methylation profiling of human chromosomes 6, 20 and 22
    • Eckhardt F., Lewin J., Cortese R., et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nature Genetics 2006, 38(12):1378-1385.
    • (2006) Nature Genetics , vol.38 , Issue.12 , pp. 1378-1385
    • Eckhardt, F.1    Lewin, J.2    Cortese, R.3
  • 79
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
    • Irizarry R.A., Ladd-Acosta C., Wen B., et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nature Genetics 2009, 41(2):178-186.
    • (2009) Nature Genetics , vol.41 , Issue.2 , pp. 178-186
    • Irizarry, R.A.1    Ladd-Acosta, C.2    Wen, B.3
  • 80
    • 39749108026 scopus 로고    scopus 로고
    • Next-generation sequencing: the race is on
    • von Bubnoff A. Next-generation sequencing: the race is on. Cell 2008, 132(5):721-723.
    • (2008) Cell , vol.132 , Issue.5 , pp. 721-723
    • von Bubnoff, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.