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Volumn 10, Issue 31, 2012, Pages 6299-6308

Redesign of enzyme for improving catalytic activity and enantioselectivity toward poor substrates: Manipulation of the transition state

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CHIRALITY; ENANTIOMERS; ENANTIOSELECTIVITY; LIPASES;

EID: 84863922133     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c2ob25614b     Document Type: Article
Times cited : (51)

References (95)
  • 11
    • 78149432825 scopus 로고    scopus 로고
    • Selected examples of directed evolution of lipases
    • M. T. Reetz Angew. Chem., Int. Ed. 2011 50 138 174
    • (2011) Angew. Chem., Int. Ed. , vol.50 , pp. 138-174
    • Reetz, M.T.1
  • 27
    • 3042636458 scopus 로고    scopus 로고
    • Rational redesign of lipases
    • T. Ema Curr. Org. Chem. 2004 8 1009 1025
    • (2004) Curr. Org. Chem. , vol.8 , pp. 1009-1025
    • Ema, T.1
  • 50
    • 20644469267 scopus 로고
    • TTN = 0.5 mmol × 0.23/(700 mg × 0.005/33,000), where 33,000 is the molecular weight of the enzyme. TOF = 1080/41, where 41 is the reaction time
    • C.-S. Chen Y. Fujimoto G. Girdaukas C. J. Sih J. Am. Chem. Soc. 1982 104 7294 7299
    • (1982) J. Am. Chem. Soc. , vol.104 , pp. 7294-7299
    • Chen, C.-S.1    Fujimoto, Y.2    Girdaukas, G.3    Sih, C.J.4
  • 52
    • 20444468574 scopus 로고    scopus 로고
    • The CH/π interaction in the ground state
    • M. Nishio Tetrahedron 2005 61 6923 6950
    • (2005) Tetrahedron , vol.61 , pp. 6923-6950
    • Nishio, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.