Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions

Angewandte Chemie - International Edition

Volumn 43, Issue 31, 2004, Pages 4075-4078

  Reetz, Manfred T ^a   Brunner, Birgit ^a   Schneider, Toni ^a   Schulz, Frank ^a   Clouthier, Christopher M ^b   Kayser, Margaret M ^b  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

^b UNIVERSITY OF NEW BRUNSWICK   (Canada)

Author keywords

Asymmetric catalysis; Baeyer Villiger reactions; Directed evolution; Enzyme catalysis; Protein engineering

Indexed keywords

AIR; CATALYSIS;

BAEYER-VILLIGER REACTIONS; CYCLOHEXANON; DESYMMETRIZATION; MONOOXYGENASE;

ENZYMES;

BACTERIAL ENZYME; CYCLOHEXANONE; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BAEYER VILLIGER REACTION; CATALYSIS; ENANTIOSELECTIVITY; EVOLUTION; NONHUMAN; PROTEIN EXPRESSION; REACTION ANALYSIS; STRUCTURE ANALYSIS;

CATALYSIS; DIRECTED MOLECULAR EVOLUTION; MUTATION; OXYGENASES; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY;

EID: 4644335310     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200460272     Document Type: Article

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