Mutations in the stereospecificity pocket and at the entrance of the active site of Candida antarctica lipase B enhancing enzyme enantioselectivity

Journal of Molecular Catalysis B: Enzymatic

Volumn 65, Issue 1-4, 2010, Pages 11-17

  Marton, Z ^a   Leonard Nevers V ^a   Syren P O ^b   Bauer, C ^a   Lamare, S ^a   Hult, K ^b   Tranc, V ^c   Graber, M ^a  

^a UNIVERSITÉ DE LA ROCHELLE   (France)

^b ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^c UNIVERSITÉ DE NANTES   (France)

Author keywords

Lipase B from Candida antarctica; Protein engineering; Stereoselective catalysis; Stereospecificity pocket; Substrate accessibility to the active site

Indexed keywords

ACTIVE SITE; LIPASE B FROM CANDIDA ANTARCTICA; PROTEIN ENGINEERING; STEREOSELECTIVE CATALYSIS; STEREOSPECIFICITY; STEREOSPECIFICITY POCKET;

BIOCHEMICAL ENGINEERING; CATALYSIS; ELECTRON TRANSITIONS; ENZYMES; GENETIC ENGINEERING; HYDROPHOBICITY; ISOMERS; STEREOSELECTIVITY; YEAST;

ENANTIOSELECTIVITY;

ALANINE; ALCOHOL DERIVATIVE; ISOLEUCINE; LEUCINE; LIPASE B; SERINE; THREONINE; VALINE;

ARTICLE; CANDIDA ANTARCTICA; CATALYSIS; CHROMATOGRAPHY; ENANTIOMER; ENANTIOSELECTIVITY; FUNGUS MUTANT; HYDROPHOBICITY; NONHUMAN; POINT MUTATION; REACTOR; STEREOSPECIFICITY; WILD TYPE;

CANDIDA ANTARCTICA;

EID: 77952583523     PISSN: 13811177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcatb.2010.01.007     Document Type: Article

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