Mutant lipase-catalyzed kinetic resolution of bulky phenyl alkyl sec-alcohols: A thermodynamic analysis of enantioselectivity

ChemBioChem

Volumn 11, Issue 3, 2010, Pages 411-416

  Vallin, Michaela ^a   Syrén, Per Olof ^a   Hult, Karl ^a  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

Enantioselectivity; Enzyme catalysis; Lipases; Thermodynamics

Indexed keywords

1 PHENYLBUTANOL; ALCOHOL DERIVATIVE; CARBON; CYCLOHEXANE; FUNGAL ENZYME; LIPASE B; PHENETHYL ALCOHOL; PHENYLPROPANOL; UNCLASSIFIED DRUG; VINYL ACETATE;

ARTICLE; BIOCATALYST; CANDIDA ANTARCTICA; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENANTIOMER; ENANTIOSELECTIVITY; ENTHALPY; ENTROPY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; KINETICS; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; TEMPERATURE SENSITIVITY;

ALCOHOLS; AMINO ACID SUBSTITUTION; BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; COMPUTER SIMULATION; KINETICS; LIPASE; MUTAGENESIS, SITE-DIRECTED; STEREOISOMERISM; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

CANDIDA ANTARCTICA;

EID: 76649139801     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900635     Document Type: Article

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