Directed evolution of an amine oxidase for the preparative deracemisation of cyclic secondary amines

ChemBioChem

Volumn 6, Issue 4, 2005, Pages 637-639

  Carr, Reuben ^a   Alexeeva, Marina ^a   Dawson, Michael J ^b   Gotor Fernández, Vicente ^a   Humphrey, Cara E ^a   Turner, Nicholas J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

Author keywords

Amine oxidase; Amines; Biocatalysis; Deracemisation; Directed evolution; Enantioselectivity

Indexed keywords

AMINE; AMINE OXIDASE (FLAVIN CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B;

ARTICLE; ASPERGILLUS NIGER; CATALYSIS; CHEMICAL STRUCTURE; DERACEMIZATION; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; RACEMIZATION;

AMINES; AMINO ACID SUBSTITUTION; ASPERGILLUS NIGER; CATALYTIC DOMAIN; DIRECTED MOLECULAR EVOLUTION; ENZYMES, IMMOBILIZED; HUMANS; KINETICS; MODELS, MOLECULAR; MONOAMINE OXIDASE; PARGYLINE; PHENETHYLAMINES; PROTEIN ENGINEERING; SEQUENCE HOMOLOGY, AMINO ACID; STEREOISOMERISM; TETRAHYDROISOQUINOLINES;

ASPERGILLUS NIGER;

EID: 21044439352     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400329     Document Type: Article

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