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Volumn 4, Issue 10, 2008, Pages

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

(17)  Ku, Manching a,b,c   Koche, Richard P a,c   Rheinbay, Esther a,c,d   Mendenhall, Eric M a,b,c   Endoh, Mitsuhiro e   Mikkelsen, Tarjei S c   Presser, Aviva c,f   Nusbaum, Chad c   Xie, Xiaohui g   Chi, Andrew S a,c   Adli, Mazhar a,b,c   Kasif, Simon d   Ptaszek, Leon M a,h,i   Cowan, Chad A h,i   Lander, Eric S c,j   Koseki, Haruhiko e   Bernstein, Bradley E a,b,c,h  


Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; HISTONE; LYSINE; PROTEIN PRC1; PROTEIN PRC2; UNCLASSIFIED DRUG; JMJD3 PROTEIN, MOUSE; N DEMETHYLASE; POLYCOMB GROUP PROTEIN; REPRESSOR PROTEIN;

EID: 55449105221     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000242     Document Type: Article
Times cited : (831)

References (65)
  • 1
    • 39149130361 scopus 로고    scopus 로고
    • Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
    • Jaenisch R, Young R (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132: 567-582.
    • (2008) Cell , vol.132 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 3
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • Sparmann A, van Lohuizen M (2006) Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6: 846-856.
    • (2006) Nat Rev Cancer , vol.6 , pp. 846-856
    • Sparmann, A.1    van Lohuizen, M.2
  • 4
    • 33846983276 scopus 로고    scopus 로고
    • Polycomb/Trithorax response elements and epigenetic memory of cell identity
    • Ringrose L, Paro R (2007) Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development 134: 223-232.
    • (2007) Development , vol.134 , pp. 223-232
    • Ringrose, L.1    Paro, R.2
  • 5
    • 7744228427 scopus 로고    scopus 로고
    • Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation
    • de Napoles M, Mermoud JE, Wakao R, Tang YA, Endoh M, et al. (2004) Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell 7: 663-676.
    • (2004) Dev Cell , vol.7 , pp. 663-676
    • de Napoles, M.1    Mermoud, J.E.2    Wakao, R.3    Tang, Y.A.4    Endoh, M.5
  • 6
    • 7244234099 scopus 로고    scopus 로고
    • Role of histone H2A ubiquitination in Polycomb silencing
    • Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, et al. (2004) Role of histone H2A ubiquitination in Polycomb silencing. Nature 431: 873-878.
    • (2004) Nature , vol.431 , pp. 873-878
    • Wang, H.1    Wang, L.2    Erdjument-Bromage, H.3    Vidal, M.4    Tempst, P.5
  • 7
    • 38149098408 scopus 로고    scopus 로고
    • Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation
    • Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, et al. (2008) Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell 29: 69-80.
    • (2008) Mol Cell , vol.29 , pp. 69-80
    • Zhou, W.1    Zhu, P.2    Wang, J.3    Pascual, G.4    Ohgi, K.A.5
  • 8
    • 36749089980 scopus 로고    scopus 로고
    • Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells
    • Stock JK, Giadrossi S, Casanova M, Brookes E, Vidal M, et al. (2007) Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells. Nat Cell Biol 9: 1428-1435.
    • (2007) Nat Cell Biol , vol.9 , pp. 1428-1435
    • Stock, J.K.1    Giadrossi, S.2    Casanova, M.3    Brookes, E.4    Vidal, M.5
  • 9
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, et al. (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441: 349-353.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3    Brambrink, T.4    Medeiros, L.A.5
  • 10
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K (2006) Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev 20: 1123-1136.
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 11
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125: 301-313.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5
  • 12
    • 33745604636 scopus 로고    scopus 로고
    • Suz12 binds to silenced regions of the genome in a cell-type-specific manner
    • Squazzo SL, O'Geen H, Komashko VM, Krig SR, Jin VX, et al. (2006) Suz12 binds to silenced regions of the genome in a cell-type-specific manner. Genome Res 16: 890-900.
    • (2006) Genome Res , vol.16 , pp. 890-900
    • Squazzo, S.L.1    O'Geen, H.2    Komashko, V.M.3    Krig, S.R.4    Jin, V.X.5
  • 13
    • 44449104974 scopus 로고    scopus 로고
    • Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity
    • Endoh M, Endo TA, Endoh T, Fujimura Y, Ohara O, et al. (2008) Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity. Development 135: 1513-1524.
    • (2008) Development , vol.135 , pp. 1513-1524
    • Endoh, M.1    Endo, T.A.2    Endoh, T.3    Fujimura, Y.4    Ohara, O.5
  • 15
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5
  • 16
    • 34547624303 scopus 로고    scopus 로고
    • Genomewide maps of chromatin state in pluripotent and lineage-committed cells
    • Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, et al. (2007) Genomewide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448: 553-560.
    • (2007) Nature , vol.448 , pp. 553-560
    • Mikkelsen, T.S.1    Ku, M.2    Jaffe, D.B.3    Issac, B.4    Lieberman, E.5
  • 17
    • 34548434716 scopus 로고    scopus 로고
    • Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
    • Pan G, Tian S, Nie J, Yang C, Ruotti V, et al. (2007) Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1: 299-312.
    • (2007) Cell Stem Cell , vol.1 , pp. 299-312
    • Pan, G.1    Tian, S.2    Nie, J.3    Yang, C.4    Ruotti, V.5
  • 18
    • 34548424709 scopus 로고    scopus 로고
    • Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells
    • Zhao XD, Han X, Chew JL, Liu J, Chiu KP, et al. (2007) Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell 1: 286-298.
    • (2007) Cell Stem Cell , vol.1 , pp. 286-298
    • Zhao, X.D.1    Han, X.2    Chew, J.L.3    Liu, J.4    Chiu, K.P.5
  • 19
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, et al. (2007) High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837.
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.Y.4    Schones, D.E.5
  • 20
    • 13744252631 scopus 로고    scopus 로고
    • Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state
    • Wei CL, Miura T, Robson P, Lim SK, Xu XQ, et al. (2005) Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells 23: 166-185.
    • (2005) Stem Cells , vol.23 , pp. 166-185
    • Wei, C.L.1    Miura, T.2    Robson, P.3    Lim, S.K.4    Xu, X.Q.5
  • 21
    • 7244240749 scopus 로고    scopus 로고
    • Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3
    • Besser D (2004) Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3. J Biol Chem 279: 45076-45084.
    • (2004) J Biol Chem , vol.279 , pp. 45076-45084
    • Besser, D.1
  • 22
    • 18744375483 scopus 로고    scopus 로고
    • Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
    • Xu RH, Peck RM, Li DS, Feng X, Ludwig T, et al. (2005) Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2: 185-190.
    • (2005) Nat Methods , vol.2 , pp. 185-190
    • Xu, R.H.1    Peck, R.M.2    Li, D.S.3    Feng, X.4    Ludwig, T.5
  • 24
    • 34447528757 scopus 로고    scopus 로고
    • New cell lines from mouse epiblast share defining features with human embryonic stem cells
    • Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, et al. (2007) New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448: 196-199.
    • (2007) Nature , vol.448 , pp. 196-199
    • Tesar, P.J.1    Chenoweth, J.G.2    Brook, F.A.3    Davies, T.J.4    Evans, E.P.5
  • 25
    • 0037644786 scopus 로고    scopus 로고
    • Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm
    • Goldin SN, Papaioannou VE (2003) Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm. Genesis 36: 40-47.
    • (2003) Genesis , vol.36 , pp. 40-47
    • Goldin, S.N.1    Papaioannou, V.E.2
  • 26
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38: 431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3    Vega, V.B.4    Zhang, W.5
  • 28
    • 33847076246 scopus 로고    scopus 로고
    • Genetic and epigenetic regulators of pluripotency
    • Surani MA, Hayashi K, Hajkova P (2007) Genetic and epigenetic regulators of pluripotency. Cell 128: 747-762.
    • (2007) Cell , vol.128 , pp. 747-762
    • Surani, M.A.1    Hayashi, K.2    Hajkova, P.3
  • 29
    • 51649129596 scopus 로고    scopus 로고
    • Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
    • Mohn F, Weber M, Rebhan M, Roloff TC, Richter J, et al. (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 30: 755-766.
    • (2008) Mol Cell , vol.30 , pp. 755-766
    • Mohn, F.1    Weber, M.2    Rebhan, M.3    Roloff, T.C.4    Richter, J.5
  • 30
    • 20044366725 scopus 로고    scopus 로고
    • Highly conserved non-coding sequences are associated with vertebrate development
    • Woolfe A, Goodson M, Goode DK, Snell P, McEwen GK, et al. (2005) Highly conserved non-coding sequences are associated with vertebrate development. PLoS Biol 3: e7.
    • (2005) PLoS Biol , vol.3
    • Woolfe, A.1    Goodson, M.2    Goode, D.K.3    Snell, P.4    McEwen, G.K.5
  • 31
    • 28644447707 scopus 로고    scopus 로고
    • Genome sequence, comparative analysis and haplotype structure of the domestic dog
    • Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, et al. (2005) Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438: 803-819.
    • (2005) Nature , vol.438 , pp. 803-819
    • Lindblad-Toh, K.1    Wade, C.M.2    Mikkelsen, T.S.3    Karlsson, E.K.4    Jaffe, D.B.5
  • 33
    • 33645231102 scopus 로고    scopus 로고
    • Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin
    • Bernstein E, Duncan EM, Masui O, Gil J, Heard E, et al. (2006) Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. Mol Cell Biol 26: 2560-2569.
    • (2006) Mol Cell Biol , vol.26 , pp. 2560-2569
    • Bernstein, E.1    Duncan, E.M.2    Masui, O.3    Gil, J.4    Heard, E.5
  • 36
    • 0031877016 scopus 로고    scopus 로고
    • Combining evidence using p-values: Application to sequence homology searches
    • Bailey TL, Gribskov M (1998) Combining evidence using p-values: application to sequence homology searches. Bioinformatics 14: 48-54.
    • (1998) Bioinformatics , vol.14 , pp. 48-54
    • Bailey, T.L.1    Gribskov, M.2
  • 37
    • 0025855079 scopus 로고
    • The myoD gene family: Nodal point during specification of the muscle cell lineage
    • Weintraub H, Davis R, Tapscott S, Thayer M, Krause M, et al. (1991) The myoD gene family: nodal point during specification of the muscle cell lineage. Science 251: 761-766.
    • (1991) Science , vol.251 , pp. 761-766
    • Weintraub, H.1    Davis, R.2    Tapscott, S.3    Thayer, M.4    Krause, M.5
  • 38
    • 0032584104 scopus 로고    scopus 로고
    • The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis
    • Yamada Y, Warren AJ, Dobson C, Forster A, Pannell R, et al. (1998) The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis. Proc Natl Acad Sci U S A 95: 3890-3895.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3890-3895
    • Yamada, Y.1    Warren, A.J.2    Dobson, C.3    Forster, A.4    Pannell, R.5
  • 39
    • 0031961239 scopus 로고    scopus 로고
    • POU domain genes are differentially expressed in the early stages after lineage commitment of the PNS-derived stem cell line, RT4-AC
    • Donahue LM, Reinhart AJ (1998) POU domain genes are differentially expressed in the early stages after lineage commitment of the PNS-derived stem cell line, RT4-AC. Brain Res Dev Brain Res 106: 1-12.
    • (1998) Brain Res Dev Brain Res , vol.106 , pp. 1-12
    • Donahue, L.M.1    Reinhart, A.J.2
  • 40
    • 0033573035 scopus 로고    scopus 로고
    • T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification
    • Yamaguchi TP, Takada S, Yoshikawa Y, Wu N, McMahon AP (1999) T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev 13: 3185-3190.
    • (1999) Genes Dev , vol.13 , pp. 3185-3190
    • Yamaguchi, T.P.1    Takada, S.2    Yoshikawa, Y.3    Wu, N.4    McMahon, A.P.5
  • 42
    • 34250159524 scopus 로고    scopus 로고
    • Genome-wide mapping of in vivo protein-DNA interactions
    • Johnson DS, Mortazavi A, Myers RM, Wold B (2007) Genome-wide mapping of in vivo protein-DNA interactions. Science 316: 1497-1502.
    • (2007) Science , vol.316 , pp. 1497-1502
    • Johnson, D.S.1    Mortazavi, A.2    Myers, R.M.3    Wold, B.4
  • 43
    • 0035449998 scopus 로고    scopus 로고
    • The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle
    • Ellis T, Gambardella L, Horcher M, Tschanz S, Capol J, et al. (2001) The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle. Genes Dev 15: 2307-2319.
    • (2001) Genes Dev , vol.15 , pp. 2307-2319
    • Ellis, T.1    Gambardella, L.2    Horcher, M.3    Tschanz, S.4    Capol, J.5
  • 44
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S (2004) Signaling to NF-kappaB. Genes Dev 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 45
    • 38849204756 scopus 로고    scopus 로고
    • Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3
    • Torres J, Watt FM (2008) Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3. Nat Cell Biol 10: 194-201.
    • (2008) Nat Cell Biol , vol.10 , pp. 194-201
    • Torres, J.1    Watt, F.M.2
  • 46
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • Kim J, Chu J, Shen X, Wang J, Orkin SH (2008) An extended transcriptional network for pluripotency of embryonic stem cells. Cell 132: 1049-1061.
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3    Wang, J.4    Orkin, S.H.5
  • 47
    • 34548411011 scopus 로고    scopus 로고
    • Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells
    • Grskovic M, Chaivorapol C, Gaspar-Maia A, Li H, Ramalho-Santos M (2007) Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells. PLoS Genet 3: e145.
    • (2007) PLoS Genet , vol.3
    • Grskovic, M.1    Chaivorapol, C.2    Gaspar-Maia, A.3    Li, H.4    Ramalho-Santos, M.5
  • 48
    • 34547641224 scopus 로고    scopus 로고
    • Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family
    • Hollenhorst PC, Shah AA, Hopkins C, Graves BJ (2007) Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes Dev 21: 1882-1894.
    • (2007) Genes Dev , vol.21 , pp. 1882-1894
    • Hollenhorst, P.C.1    Shah, A.A.2    Hopkins, C.3    Graves, B.J.4
  • 49
    • 33646856965 scopus 로고    scopus 로고
    • Chromosomal distribution of PcG proteins during Drosophila development
    • Negre N, Hennetin J, Sun LV, Lavrov S, Bellis M, et al. (2006) Chromosomal distribution of PcG proteins during Drosophila development. PLoS Biol 4: e170.
    • (2006) PLoS Biol , vol.4
    • Negre, N.1    Hennetin, J.2    Sun, L.V.3    Lavrov, S.4    Bellis, M.5
  • 50
    • 33745225872 scopus 로고    scopus 로고
    • Genomewide analysis of Polycomb targets in Drosophila melanogaster
    • Schwartz YB, Kahn TG, Nix DA, Li XY, Bourgon R, et al. (2006) Genomewide analysis of Polycomb targets in Drosophila melanogaster. Nat Genet 38: 700-705.
    • (2006) Nat Genet , vol.38 , pp. 700-705
    • Schwartz, Y.B.1    Kahn, T.G.2    Nix, D.A.3    Li, X.Y.4    Bourgon, R.5
  • 51
    • 33745258986 scopus 로고    scopus 로고
    • Genomewide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster
    • Tolhuis B, de Wit E, Muijrers I, Teunissen H, Talhout W, et al. (2006) Genomewide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster. Nat Genet 38: 694-699.
    • (2006) Nat Genet , vol.38 , pp. 694-699
    • Tolhuis, B.1    de Wit, E.2    Muijrers, I.3    Teunissen, H.4    Talhout, W.5
  • 52
    • 0000723156 scopus 로고    scopus 로고
    • Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1
    • Voo KS, Carlone DL, Jacobsen BM, Flodin A, Skalnik DG (2000) Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1. Mol Cell Biol 20: 2108-2121.
    • (2000) Mol Cell Biol , vol.20 , pp. 2108-2121
    • Voo, K.S.1    Carlone, D.L.2    Jacobsen, B.M.3    Flodin, A.4    Skalnik, D.G.5
  • 53
    • 0037082439 scopus 로고    scopus 로고
    • The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation
    • Birke M, Schreiner S, Garcia-Cuellar MP, Mahr K, Titgemeyer F, et al. (2002) The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation. Nucleic Acids Res 30: 958-965.
    • (2002) Nucleic Acids Res , vol.30 , pp. 958-965
    • Birke, M.1    Schreiner, S.2    Garcia-Cuellar, M.P.3    Mahr, K.4    Titgemeyer, F.5
  • 54
    • 34248169728 scopus 로고    scopus 로고
    • The polycomb group protein Suz12 is required for embryonic stem cell differentiation
    • Pasini D, Bracken AP, Hansen JB, Capillo M, Helin K (2007) The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol Cell Biol 27: 3769-3779.
    • (2007) Mol Cell Biol , vol.27 , pp. 3769-3779
    • Pasini, D.1    Bracken, A.P.2    Hansen, J.B.3    Capillo, M.4    Helin, K.5
  • 56
    • 34249909232 scopus 로고    scopus 로고
    • Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
    • Maherali N, Sridharan R, Xie W, Utikal J, Eminli S, et al. (2007) Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1: 55-70.
    • (2007) Cell Stem Cell , vol.1 , pp. 55-70
    • Maherali, N.1    Sridharan, R.2    Xie, W.3    Utikal, J.4    Eminli, S.5
  • 57
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, et al. (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454: 766-770.
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1    Mikkelsen, T.S.2    Gu, H.3    Wernig, M.4    Hanna, J.5
  • 59
    • 0037023544 scopus 로고    scopus 로고
    • HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
    • Kyba M, Perlingeiro RC, Daley GQ (2002) HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 109: 29-37.
    • (2002) Cell , vol.109 , pp. 29-37
    • Kyba, M.1    Perlingeiro, R.C.2    Daley, G.Q.3
  • 61
    • 0035573732 scopus 로고    scopus 로고
    • Production of monoclonal antibodies against mammalian Ring1B proteins
    • Atsuta T, Fujimura S, Moriya H, Vidal M, Akasaka T, et al. (2001) Production of monoclonal antibodies against mammalian Ring1B proteins. Hybridoma 20: 43-46.
    • (2001) Hybridoma , vol.20 , pp. 43-46
    • Atsuta, T.1    Fujimura, S.2    Moriya, H.3    Vidal, M.4    Akasaka, T.5
  • 64
    • 0034201441 scopus 로고    scopus 로고
    • EMBOSS: The European Molecular Biology Open Software Suite
    • Rice P, Longden I, Bleasby A (2000) EMBOSS: the European Molecular Biology Open Software Suite. Trends Genet 16: 276-277.
    • (2000) Trends Genet , vol.16 , pp. 276-277
    • Rice, P.1    Longden, I.2    Bleasby, A.3
  • 65
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals
    • Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, et al. (2005) Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 434: 338-345.
    • (2005) Nature , vol.434 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3    Golub, T.R.4    Mootha, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.