Downstream reactions and engineering in the microbially reconstituted pathway for Taxol

Applied Microbiology and Biotechnology

Volumn 94, Issue 4, 2012, Pages 841-849

  Jiang, Ming ^a   Stephanopoulos, Gregory ^b   Pfeifer, Blaine A ^a  

^a State University of New York   (United States)

^b Massachusetts Institute of Technology   (United States)

Author keywords

E. coli; Heterologous biosynthesis; Metabolic engineering; Natural products; S. cerevisiae; Taxol

Indexed keywords

ANTICANCER ACTIVITIES; BRISTOL-MYERS SQUIBB; E. COLI; ECONOMICAL PRODUCTION PROCESS; ENHANCED PROPERTIES; ISOPRENOIDS; NATURAL PRODUCTS; REACTION STEPS; S.CEREVISIAE; TAXOL; YEW TREE;

BIOACTIVITY; METABOLIC ENGINEERING;

BIOSYNTHESIS;

ECHINOMYCIN; ERYTHROMYCIN; FARNESYL TRANS TRANSFERASE; NATURAL PRODUCT; PACLITAXEL;

BIOACTIVITY; BIOENGINEERING; COLIFORM BACTERIUM; REACTION KINETICS; YEAST;

BIOSYNTHESIS; DRUG STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION; METABOLIC ENGINEERING; NONHUMAN; REVIEW; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PACLITAXEL; SACCHAROMYCES CEREVISIAE; TAXUS;

TAXUS BREVIFOLIA;

EID: 84862873972     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4016-1     Document Type: Review

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