-
1
-
-
0023812652
-
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
-
Kane, J.; Honigfeld, G.; Singer, J.; Meltzer, H.Y. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch. Gen. Psychiatry, 1988, 45, 789-796.
-
(1988)
Arch. Gen. Psychiatry
, vol.45
, pp. 789-796
-
-
Kane, J.1
Honigfeld, G.2
Singer, J.3
Meltzer, H.Y.4
-
2
-
-
0033522429
-
A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia
-
Lee, M.A.; Jayathilake, K.; Meltzer, H.Y. A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic-responsive schizophrenia. Schiz. Res., 1999, 37, 1-11.
-
(1999)
Schiz. Res
, vol.37
, pp. 1-11
-
-
Lee, M.A.1
Jayathilake, K.2
Meltzer, H.Y.3
-
3
-
-
76749104144
-
Pimavanserin, a serotonin(2A) receptor inverse agonist, for the treatment of Parkinson's Disease psychosis
-
Meltzer, H.Y.; Mills, R.; Revell, S.; Williams, H.; Johnson, A.; Bahr, D.; Friedman, J.H. Pimavanserin, a serotonin(2A) receptor inverse agonist, for the treatment of Parkinson's Disease psychosis. Neuropsychopharmacology, 2010, 35(4), 881-892.
-
(2010)
Neuropsychopharmacology
, vol.35
, Issue.4
, pp. 881-892
-
-
Meltzer, H.Y.1
Mills, R.2
Revell, S.3
Williams, H.4
Johnson, A.5
Bahr, D.6
Friedman, J.H.7
-
4
-
-
0345258416
-
Serotonin receptors: Their key role in drugs to treat schizophrenia
-
2003 Oct
-
Meltzer, H.Y.; Li, Z.; Kaneda, Y.; Ichikawa. Serotonin receptors: their key role in drugs to treat schizophrenia. Prog. Neuropsychopharmacol. Biol., 2003 Oct, 27(7), 1159-1172.
-
Prog. Neuropsychopharmacol. Biol
, vol.27
, Issue.7
, pp. 1159-1172
-
-
Meltzer, H.Y.1
Li, Z.2
Kaneda, Y.3
Ichikawa4
-
5
-
-
50349096587
-
In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
-
Meltzer, H.Y.; Huang, M. In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems. Prog. Brain. Res., 2008, 172, 177-197.
-
(2008)
Prog. Brain. Res
, vol.172
, pp. 177-197
-
-
Meltzer, H.Y.1
Huang, M.2
-
6
-
-
34548348729
-
Molecular targets for treating cognitive dysfunction in schizophrenia
-
Gray, J.A.; Roth, B.L. Molecular targets for treating cognitive dysfunction in schizophrenia. Schizophr. Bull., 2007, 33(5), 1100-1119.
-
(2007)
Schizophr. Bull
, vol.33
, Issue.5
, pp. 1100-1119
-
-
Gray, J.A.1
Roth, B.L.2
-
7
-
-
0035094264
-
Does fast dissociation from the dopamine Dd(2) receptor explain the action of atypical antipsychotics?: A new hypothesis
-
Kapur, S.; Seeman, P. Does fast dissociation from the dopamine Dd(2) receptor explain the action of atypical antipsychotics?: A new hypothesis Am. J. Psychiatry., 2001, 158(3), 360-369
-
(2001)
Am. J. Psychiatry
, vol.158
, Issue.3
, pp. 360-369
-
-
Kapur, S.1
Seeman, P.2
-
8
-
-
77955931468
-
Antipsychotic dosing: How much but also how often?
-
Remington, G.; Kapur, S. Antipsychotic dosing: how much but also how often? Schizophr. Bull., 2010, 36(5), 900-903.
-
(2010)
Schizophr. Bull.
, vol.36
, Issue.5
, pp. 900-903
-
-
Remington, G.1
Kapur, S.2
-
9
-
-
63049106558
-
Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO
-
Seeman, P.; Battaglia, G.; Corti, C.; Corsi, M.; Bruno, V. Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO. Synapse, 2009, 63(3), 247-251.
-
(2009)
Synapse
, vol.63
, Issue.3
, pp. 247-251
-
-
Seeman, P.1
Battaglia, G.2
Corti, C.3
Corsi, M.4
Bruno, V.5
-
10
-
-
0028788640
-
The interactions of typical and atypical antipsychotics with the (-)2,5-dimethoxy-4- methamphetamine (DOM) discriminative stimulus
-
Fiorella, D.; Helsley, S.; Rabin, R.A.; Winter, J.C. The interactions of typical and atypical antipsychotics with the (-)2,5-dimethoxy-4- methamphetamine (DOM) discriminative stimulus. Neuropharmacol., 1995, 34, 1297-1303.
-
(1995)
Neuropharmacol
, vol.34
, pp. 1297-1303
-
-
Fiorella, D.1
Helsley, S.2
Rabin, R.A.3
Winter, J.C.4
-
11
-
-
0016814597
-
Screening hallucinogenic drugs: Systematic study of three behavioral tests
-
Silva, M.T.; Calil, H.M.; Screening hallucinogenic drugs: systematic study of three behavioral tests. Psychopharmacologia, 1975, 42(2), 163-171.
-
(1975)
Psychopharmacologia
, vol.42
, Issue.2
, pp. 163-171
-
-
Silva, M.T.1
Calil, H.M.2
-
12
-
-
77952751449
-
The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen
-
Canal, C.E.; Olaghere da Silva, U.B.; Gresch, P.J.; Watt, E.E.; Sanders-Bush, E.; Airey, D.C.; The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen. Psychopharmacology (Berl.), 2010, 2, 163-174.
-
(2010)
Psychopharmacology (Berl.)
, vol.2
, pp. 163-174
-
-
Canal, C.E.1
da Olaghere, S.U.B.2
Gresch, P.J.3
Watt, E.E.4
Sanders-Bush, E.5
Airey, D.C.6
-
13
-
-
0022930993
-
Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics
-
Mita, T.; Hanada, S.; Nishino, N.; Kuno, T.; Nakai, H.; Yamadori, T.; Mizoi, Y.; Tanaka, C. Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics. Biol. Psychiatry., 1986, 21(14), 1407-1414.
-
(1986)
Biol. Psychiatry
, vol.21
, Issue.14
, pp. 1407-1414
-
-
Mita, T.1
Hanada, S.2
Nishino, N.3
Kuno, T.4
Nakai, H.5
Yamadori, T.6
Mizoi, Y.7
Tanaka, C.8
-
14
-
-
0025921604
-
Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients
-
Arora, R.C.; Meltzer, H.Y. Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients. J. Neural. Transm. Gen. Sect., 1991, 85(1), 19-29.
-
(1991)
J. Neural. Transm. Gen. Sect
, vol.85
, Issue.1
, pp. 19-29
-
-
Arora, R.C.1
Meltzer, H.Y.2
-
15
-
-
0027437017
-
Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. A postmortem study
-
Laruelle, M.; Abi-Dargham, A.; Casanova, M.F.; Toti, R.; Weinberger, D.R.; Kleinman, J.E. Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. A postmortem study. Arch. Gen. Psychiatry., 1993, 50(10), 810-818.
-
(1993)
Arch. Gen. Psychiatry
, vol.50
, Issue.10
, pp. 810-818
-
-
Laruelle, M.1
Abi-Dargham, A.2
Casanova, M.F.3
Toti, R.4
Weinberger, D.R.5
Kleinman, J.E.6
-
16
-
-
0030273870
-
5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia
-
Burnet, P.W.; Eastwood, S.L.; Harrison, P.J. 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia. Neuropsychopharmacology, 1996, 15(5), 442-455.
-
(1996)
Neuropsychopharmacology
, vol.15
, Issue.5
, pp. 442-455
-
-
Burnet, P.W.1
Eastwood, S.L.2
Harrison, P.J.3
-
17
-
-
0032216770
-
Decreased serotonin2A receptors in Brodmann's area 9 from schizophrenic subjects. A pathological or pharmacological phenomenon?
-
Dean, B.; Hayes, W.; Hill, C.; Copolov, D. Decreased serotonin2A receptors in Brodmann's area 9 from schizophrenic subjects. A pathological or pharmacological phenomenon? Mol. Chem. Neuropathol., 1998, 34(2-3),133-145.
-
(1998)
Mol. Chem. Neuropathol
, vol.34
, Issue.2-3
, pp. 133-145
-
-
Dean, B.1
Hayes, W.2
Hill, C.3
Copolov, D.4
-
18
-
-
0034617336
-
Serotonin(2A) receptors are reduced in the planum temporale from subjects with schizophrenia
-
Pralong, D.; Tomaskovic-Crook, E.; Opeskin, K.; Copolov, D.; Dean, B. Serotonin(2A) receptors are reduced in the planum temporale from subjects with schizophrenia. Schizophr. Res., 2000, 44(1), 35-45.
-
(2000)
Schizophr. Res.
, vol.44
, Issue.1
, pp. 35-45
-
-
Pralong, D.1
Tomaskovic-Crook, E.2
Opeskin, K.3
Copolov, D.4
Dean, B.5
-
19
-
-
17444423355
-
5-HT2A and muscarinic receptors in schizophrenia: A postmortem study
-
Matsumoto, I.; Inoue, Y.; Iwazaki, T.; Pavey, G.; Dean, B. 5-HT2A and muscarinic receptors in schizophrenia: a postmortem study. Neurosci. Lett., 2005, 379(3), 164-168.
-
(2005)
Neurosci. Lett
, vol.379
, Issue.3
, pp. 164-168
-
-
Matsumoto, I.1
Inoue, Y.2
Iwazaki, T.3
Pavey, G.4
Dean, B.5
-
20
-
-
4544253890
-
The atypical antipsychotic drug clozapine enhances chronic PCP-induced regulation of prefrontal cortex 5-HT2A receptors
-
2004 Sep
-
Steward, L.J.; Kennedy, M.D.; Morris, B.J.; Pratt, J.A. The atypical antipsychotic drug clozapine enhances chronic PCP-induced regulation of prefrontal cortex 5-HT2A receptors. Neuropharmacology, 2004 Sep, 47(4), 527-537.
-
Neuropharmacology
, vol.47
, Issue.4
, pp. 527-537
-
-
Steward, L.J.1
Kennedy, M.D.2
Morris, B.J.3
Pratt, J.A.4
-
21
-
-
50249163806
-
Evidence for altered post-receptor modulation of the serotonin 2a receptor in schizophrenia
-
Dean, B.; Crossland, N.; Boer, S.; Scarr, E. Evidence for altered post-receptor modulation of the serotonin 2a receptor in schizophrenia. Schizophr. Res., 2008, 104(1/3), 185-197.
-
(2008)
Schizophr. Res
, vol.104
, Issue.1-3
, pp. 185-197
-
-
Dean, B.1
Crossland, N.2
Boer, S.3
Scarr, E.4
-
22
-
-
0034650980
-
Abnormalities in 5-HT2A receptor mRNA expression in frontal cortex of chronic elderly schizophrenics with varying histories of neuroleptic treatment
-
Hernandez, I.; Sokolov, B.P. Abnormalities in 5-HT2A receptor mRNA expression in frontal cortex of chronic elderly schizophrenics with varying histories of neuroleptic treatment. J. Neurosci. Res., 2000, 59(2), 218-225.
-
(2000)
J. Neurosci. Res
, vol.59
, Issue.2
, pp. 218-225
-
-
Hernandez, I.1
Sokolov, B.P.2
-
23
-
-
79952487695
-
Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine
-
Rasmussen, H.; Ebdrup, B.H.; Erritzoe, D.; Aggernaes, B.; Oranje, B.; Kalbitzer, J.; Pinborg, L.H.; Baaré, W.F.; Svarer, C.; Lublin, H.; Knudsen, G.M.; Glenthoj, B. Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine. Psychopharmacology (Berl.), 2010, 213(2/3), 583-592.
-
(2010)
Psychopharmacology (Berl.)
, vol.213
, Issue.2-3
, pp. 583-592
-
-
Rasmussen, H.1
Ebdrup, B.H.2
Erritzoe, D.3
Aggernaes, B.4
Oranje, B.5
Kalbitzer, J.6
Pinborg, L.H.7
Baaré, W.F.8
Svarer, C.9
Lublin, H.10
Knudsen, G.M.11
Glenthoj, B.12
-
24
-
-
36349009767
-
5-HT2A receptor density is decreased in the at-risk mental state
-
Hurlemann, R.; Matusch, A.; Kuhn, K.U.; Berning, J.; Elmenhorst, D.; Winz, O.; Kolsch, H.; Zilles, K.; Wagner, M.; Maier, W.; Bauer, A. 5-HT2A receptor density is decreased in the at-risk mental state. Psychopharmacology(Berl.), 2008, 195(4), 579-590.
-
(2008)
Psychopharmacology(Berl.)
, vol.195
, Issue.4
, pp. 579-590
-
-
Hurlemann, R.1
Matusch, A.2
Kuhn, K.U.3
Berning, J.4
Elmenhorst, D.5
Winz, O.6
Kolsch, H.7
Zilles, K.8
Wagner, M.9
Maier, W.10
Bauer, A.11
-
25
-
-
0024466603
-
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D1, D2, and serotonin2 pKi values
-
Meltzer, H.Y.; Matsubara, S.; Lee, J.C. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D1, D2, and serotonin2 pKi values. J. Pharmacol. Exp. Ther., 1989, 251, 238-246.
-
(1989)
J. Pharmacol. Exp. Ther
, vol.251
, pp. 238-246
-
-
Meltzer, H.Y.1
Matsubara, S.2
Lee, J.C.3
-
26
-
-
0029930927
-
Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding
-
Schotte, A.; Janssen, P.F.; Gommeren, W.; Luyten, W.H.; Van Gompel, P.; Lesage, A.S.; De Loore, K.; Leysen J.E. Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacol., 1996, 124, 57-73.
-
(1996)
Psychopharmacol
, vol.124
, pp. 57-73
-
-
Schotte, A.1
Janssen, P.F.2
Gommeren, W.3
Luyten, W.H.4
van Gompel, P.5
Lesage, A.S.6
de Loore, K.7
Leysen, J.E.8
-
27
-
-
0035981179
-
Melperone in the treatment of neuroleptic-resistant schizophrenia
-
Meltzer, H.Y.; Sumiyoshi, T.; Jayathilake, K. Melperone in the treatment of neuroleptic-resistant schizophrenia. Psychiatry Res., 2001, 105(3), 201-209.
-
(2001)
Psychiatry Res
, vol.105
, Issue.3
, pp. 201-209
-
-
Meltzer, H.Y.1
Sumiyoshi, T.2
Jayathilake, K.3
-
28
-
-
0024310652
-
Melperone in the treatment of schizophrenia
-
Bjerkenstedt, L. Melperone in the treatment of schizophrenia. Acta. Psychiatr. Scand. Suppl., 1989, 352, 35-39.
-
(1989)
Acta. Psychiatr. Scand. Suppl
, vol.352
, pp. 35-39
-
-
Bjerkenstedt, L.1
-
29
-
-
4344714861
-
Aripiprazole: A review of its use in schizophrenia and schizoaffective disorder
-
Swainston Harrison, T.; Perry, C.M. Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder. Drugs, 2004, 64(15), 1715-1736.
-
(2004)
Drugs
, vol.64
, Issue.15
, pp. 1715-1736
-
-
Swainston Harrison, T.1
Perry, C.M.2
-
30
-
-
0025884239
-
An evaluation of the partial dopamine agonist terguride regarding positive symptoms reduction in schizophrenics
-
Olbrich, R.; Schanz, H. An evaluation of the partial dopamine agonist terguride regarding positive symptoms reduction in schizophrenics. J. Neural Transm. Gen. Sect., 1991, 84(3), 233-236.
-
(1991)
J. Neural Transm. Gen. Sect
, vol.84
, Issue.3
, pp. 233-236
-
-
Olbrich, R.1
Schanz, H.2
-
31
-
-
0027404072
-
Neuroendocrine Profile of SDZ HDC-912 and OPC-4392, Two New Atypical Antipsychotic Drugs, In Schizophrenic Patients
-
Duval, F.; Mokrani, M.C.; Macher, J.P.; Crocq, M.A.;, Castro J.O.; Bailey, P.; Lataste, X. Neuroendocrine profile of SDZ HDC-912 and OPC-4392, two new atypical antipsychotic drugs, in schizophrenic patients. Psychopharmacology (Berl.), 1993, 110(1/2), 177-180.
-
(1993)
Psychopharmacology (Berl.)
, vol.110
, Issue.1-2
, pp. 177-180
-
-
Duval, F.1
Mokrani, M.C.2
Macher, J.P.3
Crocq, M.A.4
Castro, J.O.5
Bailey, P.6
Lataste, X.7
-
32
-
-
73849100354
-
Lurasidone: A new drug in development for schizophrenia
-
Meyer, J.M.; Loebel, A.D.; Schweizer, E. Lurasidone: a new drug in development for schizophrenia. Expert Opin. Investig. Drugs, 2009, 18(11), 1715-1726.
-
(2009)
Expert Opin. Investig. Drugs
, vol.18
, Issue.11
, pp. 1715-1726
-
-
Meyer, J.M.1
Loebel, A.D.2
Schweizer, E.3
-
33
-
-
77953753014
-
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity
-
Ishibashi, T.; Horisawa, T.; Tokuda, K.; Ishiyama, T.; Ogasa, M.; Tagashira, R.; Matsumoto, K.; Nishikawa, H.; Ueda, Y.; Toma, S.; Oki, H.; Tanno, N.; Saji, I.; Ito, A.; Ohno, Y.; Nakamura, M. Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J. Pharmacol. Exp. Ther., 2010, 334(1), 171-181.
-
(2010)
J. Pharmacol. Exp. Ther
, vol.334
, Issue.1
, pp. 171-181
-
-
Ishibashi, T.1
Horisawa, T.2
Tokuda, K.3
Ishiyama, T.4
Ogasa, M.5
Tagashira, R.6
Matsumoto, K.7
Nishikawa, H.8
Ueda, Y.9
Toma, S.10
Oki, H.11
Tanno, N.12
Saji, I.13
Ito, A.14
Ohno, Y.15
Nakamura, M.16
-
34
-
-
33746534265
-
Interpreting the efficacy findings in the CATIE study: What clinicians should know
-
Meltzer, H.Y.; Bobo, W.V. Interpreting the efficacy findings in the CATIE study: what clinicians should know. CNS Spectr., 2006, 11(7 Suppl. 7), 14-24.
-
(2006)
CNS Spectr
, vol.11
, Issue.7 SUPPL. 7
, pp. 14-24
-
-
Meltzer, H.Y.1
Bobo, W.V.2
-
35
-
-
70449337423
-
Clinical trials design lessons from the CATIE study
-
Kraemer, H.C.; Glick, I.D.; Klein, D.F. Clinical trials design lessons from the CATIE study. Am. J. Psychiatry, 2009, (166), 1222-1228.
-
(2009)
Am. J. Psychiatry
, Issue.166
, pp. 1222-1228
-
-
Kraemer, H.C.1
Glick, I.D.2
Klein, D.F.3
-
36
-
-
67650505849
-
The CATIE and CUtLASS studies in schizophrenia: Results and implications for clinicians
-
Naber, D.; Lambert, M. The CATIE and CUtLASS studies in schizophrenia: results and implications for clinicians. CNS Drugs, 2009, 23(8),649-659.
-
(2009)
CNS Drugs
, vol.23
, Issue.8
, pp. 649-659
-
-
Naber, D.1
Lambert, M.2
-
37
-
-
21244448316
-
A metaanalysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia
-
Woodward, N.D.; Purdon, S.E.; Meltzer, H.Y.; Zald, D.H. A metaanalysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia. Int. J. Neuropsychopharmacol., 2005, 8(3), 457-472.
-
(2005)
Int. J. Neuropsychopharmacol
, vol.8
, Issue.3
, pp. 457-472
-
-
Woodward, N.D.1
Purdon, S.E.2
Meltzer, H.Y.3
Zald, D.H.4
-
38
-
-
34247643916
-
CATIE Investigators; Neurocognitive Working Group. Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial
-
Keefe, R.S.; Bilder, R.M.; Davis, S.M.; Harvey, P.D.; Palmer, B.W.; Gold, J.M.; Meltzer, H.Y.; Green, M.F.; Capuano, G.; Stroup, T.S.; McEvoy, J.P.; Swartz, M.S.; Rosenheck, R.A.; Perkins, D.O.; Davis, C.E.; Hsiao, J.K.; Lieberman, J.A. CATIE Investigators; Neurocognitive Working Group. Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial. Arch. Gen. Psychiatry, 2007, 64(6), 633-647.
-
(2007)
Arch. Gen. Psychiatry
, vol.64
, Issue.6
, pp. 633-647
-
-
Keefe, R.S.1
Bilder, R.M.2
Davis, S.M.3
Harvey, P.D.4
Palmer, B.W.5
Gold, J.M.6
Meltzer, H.Y.7
Green, M.F.8
Capuano, G.9
Stroup, T.S.10
McEvoy, J.P.11
Swartz, M.S.12
Rosenheck, R.A.13
Perkins, D.O.14
Davis, C.E.15
Hsiao, J.K.16
Lieberman, J.A.17
-
39
-
-
0031594813
-
5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites
-
Jakab, R.L.; Goldman-Rakic, P.S. 5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites. Proc. Natl. Acad. Sci. USA, 1998, 95, 735-740.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 735-740
-
-
Jakab, R.L.1
Goldman-Rakic, P.S.2
-
40
-
-
0029988896
-
Serotonin-dopamine interaction and its relevance to schizophrenia
-
Kapur, S.; Remington, G. Serotonin-dopamine interaction and its relevance to schizophrenia. Am. J. Psychiatry, 1996, 153, 466-476.
-
(1996)
Am. J. Psychiatry
, vol.153
, pp. 466-476
-
-
Kapur, S.1
Remington, G.2
-
41
-
-
0034091239
-
A positron emission tomography study of quetiapine in schizophrenia: A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy
-
Kapur, S.; Zipursky, R.; Jones, C.; Shammi, C.S.; Remington, G.; Seeman, P. A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy. Arch. Gen. Psychiatry, 2000, 57, 553-559.
-
(2000)
Arch. Gen. Psychiatry
, vol.57
, pp. 553-559
-
-
Kapur, S.1
Zipursky, R.2
Jones, C.3
Shammi, C.S.4
Remington, G.5
Seeman, P.6
-
42
-
-
0034741106
-
5-hydroxytryptamine2A receptor inverse agonists as antipsychotics
-
Weiner, D.M.; Burstein, E.S.; Nash, N.; Croston, G.E.; Currier, E.A.; Vanover, K.E.; Harvey, S.C.; Donohue, E.; Hansen, H.C.; Andersson, C.M.; Spalding, T.A.; Gibson, D.F.; Krebs-Thomson, K.; Powell, S.B.; Geyer, M.A.; Hacksell, U.; Brann, M.R. 5-hydroxytryptamine2A receptor inverse agonists as antipsychotics. J. Pharmacol. Exp. Ther., 2001, 299, 268-276.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.299
, pp. 268-276
-
-
Weiner, D.M.1
Burstein, E.S.2
Nash, N.3
Croston, G.E.4
Currier, E.A.5
Vanover, K.E.6
Harvey, S.C.7
Donohue, E.8
Hansen, H.C.9
Andersson, C.M.10
Spalding, T.A.11
Gibson, D.F.12
Krebs-Thomson, K.13
Powell, S.B.14
Geyer, M.A.15
Hacksell, U.16
Brann, M.R.17
-
43
-
-
0024429166
-
Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex
-
Matsubara, S.; Meltzer, H.Y. Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex. Life Sci., 1989, 45(15), 1397-1406.
-
(1989)
Life Sci
, vol.45
, Issue.15
, pp. 1397-1406
-
-
Matsubara, S.1
Meltzer, H.Y.2
-
44
-
-
0028989815
-
The role of 5-HT2A receptors in antipsychotic activity
-
Schmidt, C.J.; Sorensen, S.M.; Kehne, J.H.; Carr, A.A.; Palfreyman, M.G. The role of 5-HT2A receptors in antipsychotic activity Life Sci., 1995, 56, 2209-2222.
-
(1995)
Life Sci
, vol.56
, pp. 2209-2222
-
-
Schmidt, C.J.1
Sorensen, S.M.2
Kehne, J.H.3
Carr, A.A.4
Palfreyman, M.G.5
-
45
-
-
0031023562
-
Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice
-
Gleason, S.D.; Shannon, H.E. Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice. Psychopharmacol., 1997, 129,79-84.
-
(1997)
Psychopharmacol
, vol.129
, pp. 79-84
-
-
Gleason, S.D.1
Shannon, H.E.2
-
46
-
-
43849107133
-
Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion
-
Martin, P.; van den Buuse, M. Phencyclidine-induced locomotor hyperactivity is enhanced in mice after stereotaxic brain serotonin depletion. Behav. Brain Res., 2008, 191(2), 289-293.
-
(2008)
Behav. Brain Res
, vol.191
, Issue.2
, pp. 289-293
-
-
Martin, P.1
van den Buuse, M.2
-
47
-
-
0028834467
-
Reversal of dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin
-
Varty, G.B.; Higgins, G.A. Reversal of dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin. Eur. J. Pharmacol., 1995, 287, 201-205.
-
(1995)
Eur. J. Pharmacol
, vol.287
, pp. 201-205
-
-
Varty, G.B.1
Higgins, G.A.2
-
48
-
-
0028085465
-
Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine
-
Prinssen, E.P.; Ellenbroek, B.A.; Cools, A.R. Combined antagonism of adrenoceptors and dopamine and 5-HT receptors underlies the atypical profile of clozapine. Eur. J. Pharmacol., 1994, 262, 167-170.
-
(1994)
Eur. J. Pharmacol
, vol.262
, pp. 167-170
-
-
Prinssen, E.P.1
Ellenbroek, B.A.2
Cools, A.R.3
-
49
-
-
28044457735
-
The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity
-
Bortolozzi, A.; Diaz-Mataix, L.; Scorza, M.C.; Celada, P.; Artigas, F. The activation of 5-HT receptors in prefrontal cortex enhances dopaminergic activity. J. Neurochem., 2005, 95, 1597-1607.
-
(2005)
J. Neurochem
, vol.95
, pp. 1597-1607
-
-
Bortolozzi, A.1
Diaz-Mataix, L.2
Scorza, M.C.3
Celada, P.4
Artigas, F.5
-
50
-
-
33749074397
-
Glutamate and schizophrenia: Beyond the dopamine hypothesis
-
Coyle, J.T. Glutamate and schizophrenia: beyond the dopamine hypothesis. Cell Mol. Neurobiol., 2006, 26(4/6), 365-384.
-
(2006)
Cell Mol. Neurobiol
, vol.26
, Issue.4-6
, pp. 365-384
-
-
Coyle, J.T.1
-
51
-
-
34250615885
-
Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs?
-
Large, C.H. Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs? J. Psychopharmacol., 2007, 21(3), 283-301.
-
(2007)
J. Psychopharmacol
, vol.21
, Issue.3
, pp. 283-301
-
-
Large, C.H.1
-
52
-
-
0029162231
-
Subanesthetic doses of ketamine stimulate psychosis in schizophrenia
-
Lahti, A.C.; Koffel, B.; LaPorte, D.; Tamminga, C.A. Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology, 1995, 13, 9-19.
-
(1995)
Neuropsychopharmacology
, vol.13
, pp. 9-19
-
-
Lahti, A.C.1
Koffel, B.2
Laporte, D.3
Tamminga, C.A.4
-
53
-
-
0030749913
-
Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics
-
Malhotra, A.K.; Pinals, D.A.; Adler, C.M.; Elman, I.; Clifton, A.; Pickar, D.; Breier, A. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology, 1997b, 17, 141-150.
-
(1997)
Neuropsychopharmacology
, vol.17
, pp. 141-150
-
-
Malhotra, A.K.1
Pinals, D.A.2
Adler, C.M.3
Elman, I.4
Clifton, A.5
Pickar, D.6
Breier, A.7
-
54
-
-
29144513466
-
Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): A double-blind, cross-over study in healthy volunteers
-
Gouzoulis-Mayfrank, E.; Heekeren, K.; Neukirch, A.; Stoll, M.; Stock, C.; Obradovic, M.; Kovar, K.A. Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers. Pharmacopsychiatry, 2005, 38, 301-311.
-
(2005)
Pharmacopsychiatry
, vol.38
, pp. 301-311
-
-
Gouzoulis-Mayfrank, E.1
Heekeren, K.2
Neukirch, A.3
Stoll, M.4
Stock, C.5
Obradovic, M.6
Kovar, K.A.7
-
55
-
-
44449158676
-
Models of schizophrenia in humans and animals based on inhibition of NMDA receptors
-
Bubeníková-Valesová, V.; Horácek, J.; Vrajová, M.; Höschl, C. Models of schizophrenia in humans and animals based on inhibition of NMDA receptors. Neurosci. Biobehav. Rev., 2008, 32(5), 1014-1023.
-
(2008)
Neurosci. Biobehav. Rev
, vol.32
, Issue.5
, pp. 1014-1023
-
-
Bubeníková-Valesová, V.1
Horácek, J.2
Vrajová, M.3
Höschl, C.4
-
56
-
-
0029030343
-
Antipsychotic agents antagonize noncompetitive N-methyl-D-aspartate antagonist-induced behaviors
-
Corbett, R.; Camacho, F.; Woods, A.T.; Kerman, L.L.; Fishkin, R.J.; Brooks, K.; Dunn, R.W. Antipsychotic agents antagonize noncompetitive N-methyl-D-aspartate antagonist-induced behaviors. Psychopharmacology, 1995, 120(1), 67-74.
-
(1995)
Psychopharmacology
, vol.120
, Issue.1
, pp. 67-74
-
-
Corbett, R.1
Camacho, F.2
Woods, A.T.3
Kerman, L.L.4
Fishkin, R.J.5
Brooks, K.6
Dunn, R.W.7
-
57
-
-
0028870612
-
Blockade of phencyclidine- induced hyperlocomotion by MDL100,907 in rats reflects antagonism of 5-HT2A receptors
-
Maurel-Remy, S.; Bervoets, K.; Millan, M.J. Blockade of phencyclidine- induced hyperlocomotion by MDL100,907 in rats reflects antagonism of 5-HT2A receptors. Eur. J. Pharmacol., 1995, 280, R9-R11
-
(1995)
Eur. J. Pharmacol
, vol.280
-
-
Maurel-Remy, S.1
Bervoets, K.2
Millan, M.J.3
-
58
-
-
0030438479
-
Regional effects of MK-801 on dopamine release: Effects of competitive NMDA or 5-HT2A receptor blockade
-
Schmidt, C.J.; Fadayel, G.M. Regional effects of MK-801 on dopamine release: effects of competitive NMDA or 5-HT2A receptor blockade. J. Pharmacol. Exp. Ther., 1996, 277(3), 1541-1549.
-
(1996)
J. Pharmacol. Exp. Ther
, vol.277
, Issue.3
, pp. 1541-1549
-
-
Schmidt, C.J.1
Fadayel, G.M.2
-
59
-
-
0030766908
-
The apparent antipsychotic action of the 5-HT2A receptor antagonist M100907 in a mouse model of schizophrenia is counteracted by ritanserin
-
Martin, P.; Waters, N.; Carlsson, A.; Carlsson, M.L. The apparent antipsychotic action of the 5-HT2A receptor antagonist M100907 in a mouse model of schizophrenia is counteracted by ritanserin. J. Neural. Transm., 1997, 104(4/5), 561-564.
-
(1997)
J. Neural. Transm
, vol.104
, Issue.4-5
, pp. 561-564
-
-
Martin, P.1
Waters, N.2
Carlsson, A.3
Carlsson, M.L.4
-
60
-
-
0033452114
-
Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: Importance of nucleus accumbens 5- HT2A site for PCP-induced locomotion in the rat
-
Millan, M.J.; Brocco, M.; Gobert, A.; Joly, F.; Bervoets, K.; Rivet, J.M.; Newman-Tancredi, A.; Audinot, V.; Maurel, S. Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: importance of nucleus accumbens 5- HT2A site for PCP-induced locomotion in the rat. Eur. J. Neurosci., 1999, 11, 4419-4432.
-
(1999)
Eur. J. Neurosci
, vol.11
, pp. 4419-4432
-
-
Millan, M.J.1
Brocco, M.2
Gobert, A.3
Joly, F.4
Bervoets, K.5
Rivet, J.M.6
Newman-Tancredi, A.7
Audinot, V.8
Maurel, S.9
-
61
-
-
33645859330
-
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1- methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R, 3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine2A receptor inverse agonist
-
Vanover, K.E.; Weiner, D.M.; Makhay, M.; Veinbergs, I.; Gardell, L.R.; Lameh, J.; Del Tredici, A.L.; Piu, F.; Schiffer, H.H.; Ott, T.R.; Burstein, E.S.; Uldam, A.K.; Thygesen, M.B.; Schlienger, N.; Andersson, C.M.; Son, T.Y.; Harvey, S.C.; Powell, S.B.; Geyer, M.A.; Tolf, B.R.; Brann, M.R.; Davis, R.E. Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1- methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R, 3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine2A receptor inverse agonist. J. Pharmacol. Exp. Ther., 2006, 317, 910-918.
-
(2006)
J. Pharmacol. Exp. Ther
, vol.317
, pp. 910-918
-
-
Vanover, K.E.1
Weiner, D.M.2
Makhay, M.3
Veinbergs, I.4
Gardell, L.R.5
Lameh, J.6
Del Tredici, A.L.7
Piu, F.8
Schiffer, H.H.9
Ott, T.R.10
Burstein, E.S.11
Uldam, A.K.12
Thygesen, M.B.13
Schlienger, N.14
Andersson, C.M.15
Son, T.Y.16
Harvey, S.C.17
Powell, S.B.18
Geyer, M.A.19
Tolf, B.R.20
Brann, M.R.21
Davis, R.E.22
more..
-
62
-
-
34547118579
-
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models
-
Gardell, L.R.; Vanover, K.E.; Pounds, L.; Johnson, R.W.; Barido, R.; Anderson G.T.; Veinbergs, I.; Dyssegaard, A.; Brunmark, P.; Tabatabaei, A.; Davis, R.E.; Brann, M.R.; Hacksell, U.; Bonhaus, D.W. ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models. J. Pharmacol. Exp. Ther., 2007, 322(2), 862-870.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.322
, Issue.2
, pp. 862-870
-
-
Gardell, L.R.1
Vanover, K.E.2
Pounds, L.3
Johnson, R.W.4
Barido, R.5
Anderson, G.T.6
Veinbergs, I.7
Dyssegaard, A.8
Brunmark, P.9
Tabatabaei, A.10
Davis, R.E.11
Brann, M.R.12
Hacksell, U.13
Bonhaus, D.W.14
-
63
-
-
33846452995
-
Stimulation of D2 receptors in the prefrontal cortex reduces PCP-induced hyperactivity, acetylcholine release and dopamine metabolism in the nucleus accumbens
-
Del Arco, A.; Mora, F.; Mohammed, A.H.; Fuxe, K. Stimulation of D2 receptors in the prefrontal cortex reduces PCP-induced hyperactivity, acetylcholine release and dopamine metabolism in the nucleus accumbens. J. Neural. Transm., 2007, 114(2), 186-193.
-
(2007)
J. Neural. Transm
, vol.114
, Issue.2
, pp. 186-193
-
-
Del Arco, A.1
Mora, F.2
Mohammed, A.H.3
Fuxe, K.4
-
64
-
-
44649139791
-
Prefrontal cortex-nucleus accumbens interaction: In vivo modulation by dopamine and glutamate in the prefrontal cortex
-
Del Arco, A.; Mora, F. Prefrontal cortex-nucleus accumbens interaction: in vivo modulation by dopamine and glutamate in the prefrontal cortex. Pharmacol. Biochem. Behav., 2008, 90(2), 226-235.
-
(2008)
Pharmacol. Biochem. Behav
, vol.90
, Issue.2
, pp. 226-235
-
-
Del Arco, A.1
Mora, F.2
-
65
-
-
67651233525
-
Neurotransmitters and prefrontal cortexlimbic system interactions: Implications for plasticity and psychiatric disorders
-
Del Arco, A.; Mora, F. Neurotransmitters and prefrontal cortexlimbic system interactions: implications for plasticity and psychiatric disorders. J. Neural. Transm., 2009, 116(8), 941-952
-
(2009)
J. Neural. Transm
, vol.116
, Issue.8
, pp. 941-952
-
-
Del Arco, A.1
Mora, F.2
-
66
-
-
0025860762
-
Behavioral, pharmacological and biochemical effects of acute and chronic administration of ketamine in the rat
-
Lannes, B.; Micheletti, G.; Warter, J.M.; Kempf, E.; Di Scala, G. Behavioral, pharmacological and biochemical effects of acute and chronic administration of ketamine in the rat. Neurosci. Lett., 1991, 128, 177-181.
-
(1991)
Neurosci. Lett
, vol.128
, pp. 177-181
-
-
Lannes, B.1
Micheletti, G.2
Warter, J.M.3
Kempf, E.4
Di Scala, G.5
-
67
-
-
0031808409
-
Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion
-
Jentsch, D.J.; Taylor, J.R.; Roth, R.H. Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion. Neuropsychopharmacology, 1998, 19, 105-113.
-
(1998)
Neuropsychopharmacology
, vol.19
, pp. 105-113
-
-
Jentsch, D.J.1
Taylor, J.R.2
Roth, R.H.3
-
68
-
-
0021335494
-
Phencyclidine-induced locomotor activity in the rat is blocked by 6-hydroxydopamine lesion of the nucleus accumbens: Comparisons to other psychomotor stimulants
-
French, E.D.; Vantini, G. Phencyclidine-induced locomotor activity in the rat is blocked by 6-hydroxydopamine lesion of the nucleus accumbens: comparisons to other psychomotor stimulants. Psychopharmacology., 1984, 82, 83-88.
-
(1984)
Psychopharmacology
, vol.82
, pp. 83-88
-
-
French, E.D.1
Vantini, G.2
-
69
-
-
0022384285
-
Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system
-
French, E.D.; Pilapil, C.; Quirion, R. Phencyclidine binding sites in the nucleus accumbens and phencyclidine-induced hyperactivity are decreased following lesions of the mesolimbic dopamine system. Eur. J. Pharmacol., 1985, 116, 1-9
-
(1985)
Eur. J. Pharmacol
, vol.116
, pp. 1-9
-
-
French, E.D.1
Pilapil, C.2
Quirion, R.3
-
70
-
-
0025788614
-
Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons: An electrophysiological and behavioral comparison to phencyclidine
-
French, E.D.; Ferkany, J.; Abreu, M.; Levenson, S. Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons: an electrophysiological and behavioral comparison to phencyclidine. Neuropharmacology, 1991, 30(10), 1039-1046.
-
(1991)
Neuropharmacology
, vol.30
, Issue.10
, pp. 1039-1046
-
-
French, E.D.1
Ferkany, J.2
Abreu, M.3
Levenson, S.4
-
71
-
-
0025952455
-
Recent advances in the phencyclidine model of schizophrenia
-
Javitt, D.C.; Zukin, S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry, 1991, 148, 1301-1308.
-
(1991)
Am. J. Psychiatry
, vol.148
, pp. 1301-1308
-
-
Javitt, D.C.1
Zukin, S.R.2
-
72
-
-
0025875731
-
The N-methyl-D-aspartate receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats
-
Löscher, W.; Annies, R.; Hönack, D. The N-methyl-D-aspartate receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats. Neurosci. Lett., 1991, 128, 191-194.
-
(1991)
Neurosci. Lett
, vol.128
, pp. 191-194
-
-
Löscher, W.1
Annies, R.2
Hönack, D.3
-
73
-
-
33750213856
-
Clozapine and olanzapine, but not haloperidol, suppress serotonin efflux in the medial prefrontal cortex elicited by phencyclidine and ketamine
-
Amargós-Bosch, M.; López-Gil, X.; Artigas, F.; Adell, A. Clozapine and olanzapine, but not haloperidol, suppress serotonin efflux in the medial prefrontal cortex elicited by phencyclidine and ketamine. Int. J. Neuropsychopharmacol., 2006, 9(5), 565-573.
-
(2006)
Int. J. Neuropsychopharmacol
, vol.9
, Issue.5
, pp. 565-573
-
-
Amargós-Bosch, M.1
López-Gil, X.2
Artigas, F.3
Adell, A.4
-
74
-
-
0031950519
-
Rodent data and general hypothesis: Antipsychotic action exerted through 5-HT2A receptor antagonism is dependent on increased serotonergic tone
-
Martin, P.; Waters, N.; Schmidt, C.J.; Carlsson, A.; Carlsson, M.L. Rodent data and general hypothesis: antipsychotic action exerted through 5-HT2A receptor antagonism is dependent on increased serotonergic tone. J. Neural. Transm., 1998, 105(4-5), 365-396.
-
(1998)
J. Neural. Transm
, vol.105
, Issue.4-5
, pp. 365-396
-
-
Martin, P.1
Waters, N.2
Schmidt, C.J.3
Carlsson, A.4
Carlsson, M.L.5
-
75
-
-
57649121946
-
Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade
-
Calcagno, E.; Carli, M.; Baviera, M.; Invernizzi, R.W. Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade. J. Neurochem., 2009, 108, 521-532.
-
(2009)
J. Neurochem
, vol.108
, pp. 521-532
-
-
Calcagno, E.1
Carli, M.2
Baviera, M.3
Invernizzi, R.W.4
-
76
-
-
76749163673
-
Attenuation of phencyclidine-induced object recognition deficits by the combination of atypical antipsychotic drugs and pimavanserin (ACP 103), a 5-hydroxytryptamine(2A) receptor inverse agonist
-
Snigdha, S.; Horiguchi, M.; Huang, M.; Li, Z.; Shahid, M.; Neill, J.C.; Meltzer, H.Y. Attenuation of phencyclidine-induced object recognition deficits by the combination of atypical antipsychotic drugs and pimavanserin (ACP 103), a 5-hydroxytryptamine(2A) receptor inverse agonist. J. Pharmacol. Exp. Ther., 2010, 332(2), 622-631.
-
(2010)
J. Pharmacol. Exp. Ther
, vol.332
, Issue.2
, pp. 622-631
-
-
Snigdha, S.1
Horiguchi, M.2
Huang, M.3
Li, Z.4
Shahid, M.5
Neill, J.C.6
Meltzer, H.Y.7
-
77
-
-
34547118579
-
ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models
-
Gardell, L.R.; Vanover, K.E. Pounds, L.; Johnson, R.E.; Barido, R.E.; Anderson, G.T.; Veinbergs, I.; Dyssegaard, A.; Brunmark, P.; Tabatabaei, A.; Davis, R.E.; Brann, M.R.; Hacksell, U.; Bonhaus, D.W. ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models. J. Pharmacol. Exp. Ther., 2007, 322(2), 862-870.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.322
, Issue.2
, pp. 862-870
-
-
Gardell, L.R.1
Vanover, K.E.2
Pounds, L.3
Johnson, R.E.4
Barido, R.E.5
Anderson, G.T.6
Veinbergs, I.7
Dyssegaard, A.8
Brunmark, P.9
Tabatabaei, A.10
Davis, R.E.11
Brann, M.R.12
Hacksell, U.13
Bonhaus, D.W.14
-
78
-
-
79953689350
-
5- HT2a and 5-HT2c receptor antagonism enhances risperidone-induced dopamine (da) efflux in rat medial prefrontal cortex (mpfc) and diminishes it in the nucleus accumbens (NAC)
-
Huang, M.; Li, Z.; Prus, A.J.; Ichikawa, J.; Dai, J.; Meltzer, H.Y. 5- HT2a and 5-HT2c receptor antagonism enhances risperidone-induced dopamine (da) efflux in rat medial prefrontal cortex (mpfc) and diminishes it in the nucleus accumbens (NAC). Neurosci. Abs., 2005, 914, 10.
-
(2005)
Neurosci. Abs
, vol.914
, pp. 10
-
-
Huang, M.1
Li, Z.2
Prus, A.J.3
Ichikawa, J.4
Dai, J.5
Meltzer, H.Y.6
-
79
-
-
0037199768
-
5HT2A receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner
-
Liegeois, J-F.; Ichikawa, J.; Meltzer, H.Y. 5HT2A receptor antagonism potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and inhibits that in the nucleus accumbens in a dose-dependent manner. Brain Res., 2002, 947, 157-165.
-
(2002)
Brain Res
, vol.947
, pp. 157-165
-
-
Liegeois, J.-F.1
Ichikawa, J.2
Meltzer, H.Y.3
-
80
-
-
0035096016
-
5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: A possible mechanism of atypical antipsychotic-induced cortical dopamine release
-
Ichikawa, J.; Ishii, H.; Bonaccorso, S.; Fowler, W.L.; O'Laughlin, I.A.; Meltzer, H.Y. 5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release. J. Neurochem., 2001, 76(5), 1521-1531.
-
(2001)
J. Neurochem
, vol.76
, Issue.5
, pp. 1521-1531
-
-
Ichikawa, J.1
Ishii, H.2
Bonaccorso, S.3
Fowler, W.L.4
O'Laughlin, I.A.5
Meltzer, H.Y.6
-
81
-
-
0028147599
-
Interactions of plasminogen with polymerizing fibrin and its derivatives, monitored with a photoaffinity cross-linker and electron microscopy
-
Weisel, J.W.; Nagaswami, C.; Korsholm, B.; Petersen, L.C.; Suenson, E. Interactions of plasminogen with polymerizing fibrin and its derivatives, monitored with a photoaffinity cross-linker and electron microscopy. J. Mol. Biol., 1994, 235(3), 1117-1135.
-
(1994)
J. Mol. Biol
, vol.235
, Issue.3
, pp. 1117-1135
-
-
Weisel, J.W.1
Nagaswami, C.2
Korsholm, B.3
Petersen, L.C.4
Suenson, E.5
-
82
-
-
56449125612
-
Effect of ritanserin, a 5HT2A/2C antagonist, on negative symptoms of schizophrenia: A double-blind randomized placebo-controlled study
-
Akhondzadeh, S.; Malek-Hosseini, M.; Ghoreishi, A.; Raznahan, M.; Rezazadeh, S.A. Effect of ritanserin, a 5HT2A/2C antagonist, on negative symptoms of schizophrenia: a double-blind randomized placebo-controlled study. Prog. Neuropsychopharmacol. Biol. Psychiatry., 2008, 32(8), 1879-1883.
-
(2008)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.32
, Issue.8
, pp. 1879-1883
-
-
Akhondzadeh, S.1
Malek-Hosseini, M.2
Ghoreishi, A.3
Raznahan, M.4
Rezazadeh, S.A.5
-
83
-
-
0026666542
-
Biochemical and pharmacological properties of SR 46349B, a new potent and selective 5-hydroxytryptamine2 receptor antagonists
-
Rinaldi-Carmona, M.; Congy, C.; Santucci, V.; Simiand, J.; Gautret, B.; Neliat, G.; Labeeuw, B.; Le Fur, G.; Soubrié, P.G.; Breliere, J.C. Biochemical and pharmacological properties of SR 46349B, a new potent and selective 5-hydroxytryptamine2 receptor antagonists. J. Pharmacol. Exp. Ther., 1992, 262, 759-768.
-
(1992)
J. Pharmacol. Exp. Ther
, vol.262
, pp. 759-768
-
-
Rinaldi-Carmona, M.1
Congy, C.2
Santucci, V.3
Simiand, J.4
Gautret, B.5
Neliat, G.6
Labeeuw, B.7
Le-Fur, G.8
Soubrié, P.G.9
Breliere, J.C.10
-
84
-
-
2942538034
-
Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder
-
Meta-Trial Study Group
-
Meltzer, H.Y.; Arvanitis, L.; Bauer, D.; Rein, W.; Meta-Trial Study Group. Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder. Am. J. Psychiatry, 2004, 161(6), 975-984.
-
(2004)
Am. J. Psychiatry
, vol.161
, Issue.6
, pp. 975-984
-
-
Meltzer, H.Y.1
Arvanitis, L.2
Bauer, D.3
Rein, W.4
-
85
-
-
27744577804
-
ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidolinduced dopamine release in rat medial prefrontal cortex and nucleus accumbens
-
Li, Z.; Ichikawa, J.; Huang, M.; Prus, A.J.; Dai, J.; Meltzer, H.Y. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidolinduced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Psychopharmacology (Berl.), 2005, 183(2), 144-153.
-
(2005)
Psychopharmacology (Berl.)
, vol.183
, Issue.2
, pp. 144-153
-
-
Li, Z.1
Ichikawa, J.2
Huang, M.3
Prus, A.J.4
Dai, J.5
Meltzer, H.Y.6
-
86
-
-
76749104144
-
Pimavanserin, a serotonin(2A) receptor inverse agonist, for the treatment of Parkinson's Disease psychosis
-
Meltzer, H.Y.; Mills, R.; Revell, S.; Williams, H.; Johnson, A.; Bahr, D.; Friedman, J.H. Pimavanserin, a serotonin(2A) receptor inverse agonist, for the treatment of Parkinson's Disease psychosis. Neuropsychopharmacology, 2010, 35(4), 881-892.
-
(2010)
Neuropsychopharmacology
, vol.35
, Issue.4
, pp. 881-892
-
-
Meltzer, H.Y.1
Mills, R.2
Revell, S.3
Williams, H.4
Johnson, A.5
Bahr, D.6
Friedman, J.H.7
-
87
-
-
0029197942
-
Role of serotonin in the action of atypical antipsychotic drugs
-
Meltzer, H.Y. Role of serotonin in the action of atypical antipsychotic drugs. Clin. Neurosci., 1995, 3(2), 64-75.
-
(1995)
Clin. Neurosci
, vol.3
, Issue.2
, pp. 64-75
-
-
Meltzer, H.Y.1
-
88
-
-
0023274497
-
Serotonin receptors in the human brain--IV. Autoradiographic mapping of serotonin-2 receptors
-
Pazos, A.; Probst, A.; Palacios, J.M. Serotonin receptors in the human brain--IV. Autoradiographic mapping of serotonin-2 receptors. Neuroscience, 1987, 21(1), 123-139.
-
(1987)
Neuroscience
, vol.21
, Issue.1
, pp. 123-139
-
-
Pazos, A.1
Probst, A.2
Palacios, J.M.3
-
89
-
-
0033990419
-
Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin(2C/2B) receptor agonists: A combined in vivo electrophysiological and microdialysis study
-
Di Giovanni, G.; Di Matteo, V.; Di Mascio, M.; Esposito, E. Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin(2C/2B) receptor agonists: a combined in vivo electrophysiological and microdialysis study. Synapse, 2000, 35(1), 53-61.
-
(2000)
Synapse
, vol.35
, Issue.1
, pp. 53-61
-
-
Di Giovanni, G.1
Di Matteo, V.2
Di Mascio, M.3
Esposito, E.4
-
90
-
-
1842610940
-
Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens
-
De Deurwaerdère, P.; Navailles, S.; Berg, K.A.; Clarke, W.P.; Spampinato, U. Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens. J. Neurosci., 2004, 24(13), 3235-3241.
-
(2004)
J. Neurosci
, vol.24
, Issue.13
, pp. 3235-3241
-
-
de Deurwaerdère, P.1
Navailles, S.2
Berg, K.A.3
Clarke, W.P.4
Spampinato, U.5
-
91
-
-
0033515573
-
RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity
-
Niswender, C.M.; Copeland, S.C.; Herrick-Davis, K.; Emeson, R.B.; Sanders-Bush, E. RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity. J. Biol. Chem., 1999, 274(14), 9472-9478.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.14
, pp. 9472-9478
-
-
Niswender, C.M.1
Copeland, S.C.2
Herrick-Davis, K.3
Emeson, R.B.4
Sanders-Bush, E.5
-
92
-
-
34548564602
-
Mouse models to elucidate the functional roles of adenosine-to-inosine editing
-
Rula, E.Y.; Emeson, R.B. Mouse models to elucidate the functional roles of adenosine-to-inosine editing. Methods Enzymol., 2007, 424, 333-367.
-
(2007)
Methods Enzymol
, vol.424
, pp. 333-367
-
-
Rula, E.Y.1
Emeson, R.B.2
-
93
-
-
12744273085
-
How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing
-
Englander, M.T.; Dulawa, S.C.; Bhansali, P.; Schmauss, C. How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing. J. Neurosci., 2005, 25(3), 648-651
-
(2005)
J. Neurosci
, vol.25
, Issue.3
, pp. 648-651
-
-
Englander, M.T.1
Dulawa, S.C.2
Bhansali, P.3
Schmauss, C.4
-
94
-
-
33745958290
-
A-to-I editing of the 5HT2C receptor and behaviour
-
Gardiner, K.; Du, Y. A-to-I editing of the 5HT2C receptor and behaviour. Brief Funct. Genomic Proteomic., 2006, 5(1), 37-42.
-
(2006)
Brief Funct. Genomic Proteomic
, vol.5
, Issue.1
, pp. 37-42
-
-
Gardiner, K.1
Du, Y.2
-
95
-
-
33847007668
-
Early life stress alters adult serotonin 2C receptor pre-mRNA editing and expression of the alpha subunit of the heterotrimeric Gprotein G q
-
Bhansali, P.; Dunning, J.; Singer, S.E.; David, L.; Schmauss, C. Early life stress alters adult serotonin 2C receptor pre-mRNA editing and expression of the alpha subunit of the heterotrimeric Gprotein G q. J. Neurosci., 2007, 27(6), 1467-1473.
-
(2007)
J. Neurosci
, vol.27
, Issue.6
, pp. 1467-1473
-
-
Bhansali, P.1
Dunning, J.2
Singer, S.E.3
David, L.4
Schmauss, C.5
-
96
-
-
66149158193
-
Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour
-
Doe, C.M.; Relkovic S, Garfield, A.S.; Dalley, J.W.; Theobald, D.E.; Humby, T.; Wilkinson, L.S.; Isles, A.R. Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour. Hum. Mol. Genet., 2009, 18(12), 2140-2148.
-
(2009)
Hum. Mol. Genet
, vol.18
, Issue.12
, pp. 2140-2148
-
-
Doe, C.M.1
Relkovic, S.2
Garfield, A.S.3
Dalley, J.W.4
Theobald, D.E.5
Humby, T.6
Wilkinson, L.S.7
Isles, A.R.8
-
97
-
-
3042745310
-
Epigenetic activation of the 5-hydroxytryptamine (serotonin) receptor 2C in embryonal carcinoma cells is DNA replication-dependent
-
Bancescu, D.L.; Glatt-Deeley, H.; Lalande, M. Epigenetic activation of the 5-hydroxytryptamine (serotonin) receptor 2C in embryonal carcinoma cells is DNA replication-dependent. Exp. Cell. Res., 2004, 298(1), 262-267.
-
(2004)
Exp. Cell. Res
, vol.298
, Issue.1
, pp. 262-267
-
-
Bancescu, D.L.1
Glatt-Deeley, H.2
Lalande, M.3
-
98
-
-
23144441853
-
The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment
-
Reynolds, G.P.; Templeman, L.A.; Zhang, Z.J. The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment. Progr. Neuro-Psychopharmacol. Biolog. Psychiatry, 2005, 29(6), 1021-1028.
-
(2005)
Progr. Neuro-Psychopharmacol. Biolog. Psychiatry
, vol.29
, Issue.6
, pp. 1021-1028
-
-
Reynolds, G.P.1
Templeman, L.A.2
Zhang, Z.J.3
-
99
-
-
23944436696
-
A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts
-
Sodhi, M.S.; Airey, D.C.; Lambert, W.; Burnet, P.W.; Harrison, P.J.; Sanders-Bush, E. A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts. Mol. Pharmacol., 2005, 68(3), 711-719.
-
(2005)
Mol. Pharmacol
, vol.68
, Issue.3
, pp. 711-719
-
-
Sodhi, M.S.1
Airey, D.C.2
Lambert, W.3
Burnet, P.W.4
Harrison, P.J.5
Sanders-Bush, E.6
-
100
-
-
0034629513
-
Dissecting G protein-coupled receptor signaling pathways with membranepermeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells
-
Chang, M.; Zhang, L.; Tam, J.P.; Sanders-Bush, E. Dissecting G protein-coupled receptor signaling pathways with membranepermeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells. J. Biol. Chem., 2000, 275(10), 7021-7029.
-
(2000)
J. Biol. Chem
, vol.275
, Issue.10
, pp. 7021-7029
-
-
Chang, M.1
Zhang, L.2
Tam, J.P.3
Sanders-Bush, E.4
-
101
-
-
70349330851
-
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: Differential effects of inverse agonist versus antagonist
-
Leggio, G.M.; Cathala, A.; Neny, M.; Rouge-Pont, F.; Drago, F.; Piazza, P.V.; Spampinato, U. In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist. J. Neurochem., 2009, 111,614-623.
-
(2009)
J. Neurochem
, vol.111
, pp. 614-623
-
-
Leggio, G.M.1
Cathala, A.2
Neny, M.3
Rouge-Pont, F.4
Drago, F.5
Piazza, P.V.6
Spampinato, U.7
-
102
-
-
0031987361
-
Selective blockade of serotonin2C/2B receptors enhances dopamine release in the rat nucleus accumbens
-
Di Matteo, V.; Di Giovanni, G.; Di Mascio, M.; Esposito, E. Selective blockade of serotonin2C/2B receptors enhances dopamine release in the rat nucleus accumbens. Neuropharmacology., 1998, 37(2), 265-272.
-
(1998)
Neuropharmacology
, vol.37
, Issue.2
, pp. 265-272
-
-
Di Matteo, V.1
Di Giovanni, G.2
Di Mascio, M.3
Esposito, E.4
-
103
-
-
0032588764
-
SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system
-
Di Matteo, V.; Di Giovanni, G.; Di Mascio, M.; Esposito, E. SB 242084, a selective serotonin2C receptor antagonist, increases dopaminergic transmission in the mesolimbic system. Neuropharmacology, 1999, 38(8), 1195-1205.
-
(1999)
Neuropharmacology
, vol.38
, Issue.8
, pp. 1195-1205
-
-
Di Matteo, V.1
Di Giovanni, G.2
Di Mascio, M.3
Esposito, E.4
-
104
-
-
0032817813
-
Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation
-
De Deurwaerdere, P.; Spampinato, U. Role of serotonin(2A) and serotonin(2B/2C) receptor subtypes in the control of accumbal and striatal dopamine release elicited in vivo by dorsal raphe nucleus electrical stimulation. J. Neurochem., 1999, 73(3), 1033-1042.
-
(1999)
J. Neurochem
, vol.73
, Issue.3
, pp. 1033-1042
-
-
de Deurwaerdere, P.1
Spampinato, U.2
-
105
-
-
77952751449
-
The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen
-
Canal, C.E.; Olaghere da Silva, U.B.; Gresch, P.J.; Watt, E.E.; Sanders-Bush, E.; Airey, D.C. The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen. Psychopharmacology (Berl.), 2010, (2),163-174.
-
(2010)
Psychopharmacology (Berl.)
, Issue.2
, pp. 163-174
-
-
Canal, C.E.1
da Olaghere, S.U.B.2
Gresch, P.J.3
Watt, E.E.4
Sanders-Bush, E.5
Airey, D.C.6
-
106
-
-
0033799076
-
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors
-
Herrick-Davis, K.; Grinde, E.; Teitler, M. Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors. J. Pharmacol. Exp. Ther., 2000, 295(1), 226-232.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.295
, Issue.1
, pp. 226-232
-
-
Herrick-Davis, K.1
Grinde, E.2
Teitler, M.3
-
107
-
-
0026638381
-
Binding of typical and atypical antipsychotic agents to transiently expressed 5-HT1C receptors
-
Roth, B.L.; Ciaranello, R.D.; Meltzer, H.Y. Binding of typical and atypical antipsychotic agents to transiently expressed 5-HT1C receptors. J. Pharmacol. Exp. Ther., 1992, 260, 1361-1365.
-
(1992)
J. Pharmacol. Exp. Ther
, vol.260
, pp. 1361-1365
-
-
Roth, B.L.1
Ciaranello, R.D.2
Meltzer, H.Y.3
-
108
-
-
0028261434
-
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5- hydroxytryptamine-7 receptors
-
Roth, B.L.; Craigo, S.C.; Choudhary, M.S.; Uluer, A.; Monsma, F.J. Jr.; Shen, Y.; Meltzer, H.Y.; Sibley, D.R. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5- hydroxytryptamine-7 receptors. J. Pharmacol. Exp. Ther., 1994, 268(3), 1403-1410.
-
(1994)
J. Pharmacol. Exp. Ther
, vol.268
, Issue.3
, pp. 1403-1410
-
-
Roth, B.L.1
Craigo, S.C.2
Choudhary, M.S.3
Uluer, A.4
Monsma Jr., F.J.5
Shen, Y.6
Meltzer, H.Y.7
Sibley, D.R.8
-
109
-
-
20944441963
-
WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta- [b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity
-
Dunlop, J.; Sabb, A.L.; Mazandarani, H.; Zhang, J.; Kalgaonker, S.; Shukhina, E.; Sukoff, S.; Vogel, R.L.; Stack, G.; Schechter, L.; Harrison, B.L.; Rosenzweig-Lipson, S. WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta- [b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity. J. Pharmacol. Exp. Ther., 2005, 313(2), 862-869.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.313
, Issue.2
, pp. 862-869
-
-
Dunlop, J.1
Sabb, A.L.2
Mazandarani, H.3
Zhang, J.4
Kalgaonker, S.5
Shukhina, E.6
Sukoff, S.7
Vogel, R.L.8
Stack, G.9
Schechter, L.10
Harrison, B.L.11
Rosenzweig-Lipson, S.12
-
110
-
-
33845876953
-
WAY-163909 [(7bR,10aR)- 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta- [b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity
-
Marquis, K.L.; Sabb, A.L.; Logue, S.F.; Brennan, J.A.; Piesla, M.J.; Comery, T.A.; Grauer, S.M.; Ashby, C.R. Jr.; Nguyen, H.Q.; Dawson, L.A.; Barrett, J.E.; Stack, G.; Meltzer, H.Y.; Harrison, B.L.; Rosenzweig-Lipson, S. WAY-163909 [(7bR,10aR)- 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta- [b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity. J. Pharmacol. Exp. Ther., 2007, 320(1), 486-496.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.320
, Issue.1
, pp. 486-496
-
-
Marquis, K.L.1
Sabb, A.L.2
Logue, S.F.3
Brennan, J.A.4
Piesla, M.J.5
Comery, T.A.6
Grauer, S.M.7
Ashby Jr., C.R.8
Nguyen, H.Q.9
Dawson, L.A.10
Barrett, J.E.11
Stack, G.12
Meltzer, H.Y.13
Harrison, B.L.14
Rosenzweig-Lipson, S.15
-
111
-
-
50849120686
-
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5- HT2C-VSV receptors mediated Gq/11 activation and calcium mobilization in CHO cells
-
Cussac, D.; Boutet-Robinet, E.; Ailhaud, M.C.; Newman-Tancredi, A.; Martel, J.C.; Danty, N.; Rauly-Lestienne, I. Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5- HT2C-VSV receptors mediated Gq/11 activation and calcium mobilization in CHO cells. Eur. J. Pharmacol., 2008, 594(1/3), 32-38.
-
(2008)
Eur. J. Pharmacol
, vol.594
, Issue.1-3
, pp. 32-38
-
-
Cussac, D.1
Boutet-Robinet, E.2
Ailhaud, M.C.3
Newman-Tancredi, A.4
Martel, J.C.5
Danty, N.6
Rauly-Lestienne, I.7
-
112
-
-
73349135022
-
Lorcaserin and adiposopathy: 5-HT2c agonism as a treatment for 'sick fat' and metabolic disease
-
Bays, H.E. Lorcaserin and adiposopathy: 5-HT2c agonism as a treatment for 'sick fat' and metabolic disease. Expert. Rev. Cardiovasc. Ther., 2009, 7(11),1429-1445.
-
(2009)
Expert. Rev. Cardiovasc. Ther
, vol.7
, Issue.11
, pp. 1429-1445
-
-
Bays, H.E.1
-
113
-
-
33645107480
-
The 5-HT1A receptor agonist 8-OH-DPAT prevents prefrontocortical glutamate and serotonin release in response to blockade of cortical NMDA receptors
-
Calcagno, E.; Carli, M.; Invernizzi, R.W. The 5-HT1A receptor agonist 8-OH-DPAT prevents prefrontocortical glutamate and serotonin release in response to blockade of cortical NMDA receptors. J. Neurochem., 2006, 96, 853-860
-
(2006)
J. Neurochem
, vol.96
, pp. 853-860
-
-
Calcagno, E.1
Carli, M.2
Invernizzi, R.W.3
-
114
-
-
77954122304
-
The importance of 5-HT1A receptor agonism in antipsychotic drug action: Rationale and perspectives
-
Newman-Tancredi, A. The importance of 5-HT1A receptor agonism in antipsychotic drug action: Rationale and perspectives. Curr. Opin. Investig. Drugs, 2010, 11(7), 802-812.
-
(2010)
Curr. Opin. Investig. Drugs
, vol.11
, Issue.7
, pp. 802-812
-
-
Newman-Tancredi, A.1
-
115
-
-
77949484291
-
Antipsychotic medication: The potential role of 5-HT(1A) receptor agonism
-
McCreary, A.C.; Jones, C.A. Antipsychotic medication: the potential role of 5-HT(1A) receptor agonism. Curr. Pharm. Des., 2010, 16(5), 516-521.
-
(2010)
Curr. Pharm. Des
, vol.16
, Issue.5
, pp. 516-521
-
-
McCreary, A.C.1
Jones, C.A.2
-
116
-
-
0026701850
-
Antagonism by 8-OH-DPAT, but not ritanserin, of catalepsy induced by SCH 23390 in the rat
-
Wadenberg, M.L. Antagonism by 8-OH-DPAT, but not ritanserin, of catalepsy induced by SCH 23390 in the rat. J. Neural. Transm. Gen. Sect., 1992, 89, 49-59.
-
(1992)
J. Neural. Transm. Gen. Sect
, vol.89
, pp. 49-59
-
-
Wadenberg, M.L.1
-
117
-
-
0035673012
-
Extended radioligand binding profile of iloperidone: A broad spectrum dopamine/ serotonin/norepinephrine receptor antagonist for the management of psychotic disorders
-
Kalkman, H.O.; Subramanian, N.; Hoyer, D. Extended radioligand binding profile of iloperidone: a broad spectrum dopamine/ serotonin/norepinephrine receptor antagonist for the management of psychotic disorders. Neuropsychopharmacology, 2001, 25(6), 904-914.
-
(2001)
Neuropsychopharmacology
, vol.25
, Issue.6
, pp. 904-914
-
-
Kalkman, H.O.1
Subramanian, N.2
Hoyer, D.3
-
118
-
-
0031698286
-
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: A [35S]GTPgammaS binding study
-
Newman-Tancredi, A.; Gavaudan, S.; Conte, C.; Chaput, C.; Touzard, M.; Verrièle, L.; Audinot, V.; Millan, M.J. Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. Eur. J. Pharmacol., 1998, 355(2/3), 245-256.
-
(1998)
Eur. J. Pharmacol
, vol.355
, Issue.2-3
, pp. 245-256
-
-
Newman-Tancredi, A.1
Gavaudan, S.2
Conte, C.3
Chaput, C.4
Touzard, M.5
Verrièle, L.6
Audinot, V.7
Millan, M.J.8
-
119
-
-
0037195552
-
Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: Role of 5-HT1A receptor agonism
-
Ichikawa, J.; Li, Z.; Dai, J.; Meltzer, H.Y. Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism. Brain Res., 2002, 956(2), 349-357.
-
(2002)
Brain Res
, vol.956
, Issue.2
, pp. 349-357
-
-
Ichikawa, J.1
Li, Z.2
Dai, J.3
Meltzer, H.Y.4
-
120
-
-
25644452796
-
Contrasting contribution of 5-hydroxytryptamine 1a receptor activation to neurochemical profile of novel antipsychotics: Frontocor tical dopamine and hippocampal serotonin release in rat brain
-
Assié, M.B.; Ravailhe, V.; Faucillon, V.; Newman-Tancredi, A. Contrasting contribution of 5-hydroxytryptamine 1a receptor activation to neurochemical profile of novel antipsychotics: frontocor tical dopamine and hippocampal serotonin release in rat brain. J. Pharmacol. Exp. Ther., 2005, 315(1), 265-272.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.315
, Issue.1
, pp. 265-272
-
-
Assié, M.B.1
Ravailhe, V.2
Faucillon, V.3
Newman-Tancredi, A.4
-
121
-
-
0030694503
-
Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation
-
Rollema, H.; Lu, Y.; Schmidt, A.W.; Zorn, S.H. Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation. Eur. J. Pharmacol., 1997, 338, R3-5.
-
(1997)
Eur. J. Pharmacol
, vol.338
, pp. 3-5
-
-
Rollema, H.1
Lu, Y.2
Schmidt, A.W.3
Zorn, S.H.4
-
122
-
-
0036176263
-
Atypical, but not typical, antipsychotic drugs selectively increase acetylcholine release in rat medial prefrontal cortex, nucleus accumbens and striatum
-
Ichikawa, J.; Dai, J.; O'Laughlin, I.A.; Dai, J.; Fowler, W.; Meltzer, H.Y. Atypical, but not typical, antipsychotic drugs selectively increase acetylcholine release in rat medial prefrontal cortex, nucleus accumbens and striatum. Neuropsychopharmacol., 2002b, 26 (3), 325-339.
-
(2002)
Neuropsychopharmacol
, vol.26
, Issue.3
, pp. 325-339
-
-
Ichikawa, J.1
Dai, J.2
O'Laughlin, I.A.3
Dai, J.4
Fowler, W.5
Meltzer, H.Y.6
-
123
-
-
4444229040
-
Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: Role of 5-HT1A receptor agonism
-
Chung, Y.C.; Li, Z.; Dai, J.; Meltzer, H.Y.; Ichikawa, J. Clozapine increases both acetylcholine and dopamine release in rat ventral hippocampus: role of 5-HT1A receptor agonism. Brain. Res., 2004, 1023, 54-63.
-
(2004)
Brain. Res
, vol.1023
, pp. 54-63
-
-
Chung, Y.C.1
Li, Z.2
Dai, J.3
Meltzer, H.Y.4
Ichikawa, J.5
-
124
-
-
28044469011
-
Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity: Role in atypical antipsychotic action
-
Diaz-Mataix, L.; Scorza, M.C.; Bortolozzi, A.; Toth, M.; Celada, P.; Artigas, F. Involvement of 5-HT1A receptors in prefrontal cortex in the modulation of dopaminergic activity: role in atypical antipsychotic action. J. Neurosci., 2005, 25(47), 10831-10843.
-
(2005)
J. Neurosci
, vol.25
, Issue.47
, pp. 10831-10843
-
-
Diaz-Mataix, L.1
Scorza, M.C.2
Bortolozzi, A.3
Toth, M.4
Celada, P.5
Artigas, F.6
-
125
-
-
33947153819
-
F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms
-
Depoortère, R.; Auclair, A.L.; Bardin, L.; Bruins, S.L.; Kleven, M.S.; Colpaert, F.; Vacher, B.; Newman-Tancredi, A. F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms. Br. J. Pharmacol., 2007, 151(2), 266-277.
-
(2007)
Br. J. Pharmacol
, vol.151
, Issue.2
, pp. 266-277
-
-
Depoortère, R.1
Auclair, A.L.2
Bardin, L.3
Bruins, S.L.4
Kleven, M.S.5
Colpaert, F.6
Vacher, B.7
Newman-Tancredi, A.8
-
126
-
-
70349205354
-
F15063, a potential antipsychotic with dopamine D(2)/D(3) receptor antagonist and 5-HT(1A) receptor agonist properties: Influence on immediate-early gene expression in rat prefrontal cortex and striatum
-
Bruins Slot, L.A.; Lestienne, F.; Grevoz-Barret, C.; Newman- Tancredi, A.; Cussac, D. F15063, a potential antipsychotic with dopamine D(2)/D(3) receptor antagonist and 5-HT(1A) receptor agonist properties: influence on immediate-early gene expression in rat prefrontal cortex and striatum. Eur. J. Pharmacol., 2009, 620(1/3), 27-35.
-
(2009)
Eur. J. Pharmacol
, vol.620
, Issue.1-3
, pp. 27-35
-
-
Bruins Slot, L.A.1
Lestienne, F.2
Grevoz-Barret, C.3
Newman-Tancredi, A.4
Cussac, D.5
-
127
-
-
2342526545
-
Cognitive functioning in schizophrenia: A consensus statement on its role in the definition and evaluation of effective treatments for the illness
-
Harvey, P.D.; Green, M.F.; Keefe, R.S.; Velligan, D.I. Cognitive functioning in schizophrenia: a consensus statement on its role in the definition and evaluation of effective treatments for the illness. J. Clin. Psychiatry, 2004, 65(3), 361-372.
-
(2004)
J. Clin. Psychiatry
, vol.65
, Issue.3
, pp. 361-372
-
-
Harvey, P.D.1
Green, M.F.2
Keefe, R.S.3
Velligan, D.I.4
-
128
-
-
0032977410
-
The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia
-
Meltzer, H.Y.; McGurk, S.R. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr. Bull., 1999, 25, 233-255.
-
(1999)
Schizophr. Bull
, vol.25
, pp. 233-255
-
-
Meltzer, H.Y.1
McGurk, S.R.2
-
129
-
-
0027524707
-
Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine
-
Hagger, C.; Buckley, P.; Kenny, J.T.; Friedman, L.; Ubogy, D.; Meltzer, H.Y. Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine. Biol. Psychiatry., 1993, 34, 702-712.
-
(1993)
Biol. Psychiatry
, vol.34
, pp. 702-712
-
-
Hagger, C.1
Buckley, P.2
Kenny, J.T.3
Friedman, L.4
Ubogy, D.5
Meltzer, H.Y.6
-
130
-
-
0033080733
-
Ketamineinduced NMDA receptor hypofunction as a model of memory impairment and psychosis
-
Newcomer, J.W.; Farber, N.B.; Jevtovic-Todorovic, V.; Selke, G.; Melson, A.K.; Hershey, T.; Craft, S.; Olney, J.W. Ketamineinduced NMDA receptor hypofunction as a model of memory impairment and psychosis. Neuropsychopharmacology, 1999, 20(2), 106-118.
-
(1999)
Neuropsychopharmacology
, vol.20
, Issue.2
, pp. 106-118
-
-
Newcomer, J.W.1
Farber, N.B.2
Jevtovic-Todorovic, V.3
Selke, G.4
Melson, A.K.5
Hershey, T.6
Craft, S.7
Olney, J.W.8
-
131
-
-
0025879236
-
Neuropsychological function in schizophrenia: Selective impairment in memory and learning
-
Saykin, A.J.; Gur, R.C.; Gur, R.E.; Mozley, P.D.; Mozley, L.H.; Resnick, S.M.; Kester, D.B.; Stafiniak, P. Neuropsychological function in schizophrenia: Selective impairment in memory and learning. Arch. Gen. Psychiatry., 1991, 48(7), 618-624.
-
(1991)
Arch. Gen. Psychiatry
, vol.48
, Issue.7
, pp. 618-624
-
-
Saykin, A.J.1
Gur, R.C.2
Gur, R.E.3
Mozley, P.D.4
Mozley, L.H.5
Resnick, S.M.6
Kester, D.B.7
Stafiniak, P.8
-
132
-
-
0032977410
-
The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia
-
Meltzer, H.Y.; McGurk, S.R. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophr. Bull., 1999, 25, 233-255.
-
(1999)
Schizophr. Bull
, vol.25
, pp. 233-255
-
-
Meltzer, H.Y.1
McGurk, S.R.2
-
133
-
-
45449120971
-
Object recognition memory: Neurobiological mechanisms of encoding, consolidation and retrieval
-
Winters, B.D.; Saksida, L.M.; Bussey, T.J. Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval. Neurosci. Biobehav. Rev., 2008, 32(5), 1055-1070.
-
(2008)
Neurosci. Biobehav. Rev
, vol.32
, Issue.5
, pp. 1055-1070
-
-
Winters, B.D.1
Saksida, L.M.2
Bussey, T.J.3
-
134
-
-
77954167498
-
Implications of animal object memory research for human amnesia
-
Winters, B.D.; Saksida, L.M.; Bussey, T.J. Implications of animal object memory research for human amnesia. Neuropsychologia, 2010, 48, 2251-2261
-
(2010)
Neuropsychologia
, vol.48
, pp. 2251-2261
-
-
Winters, B.D.1
Saksida, L.M.2
Bussey, T.J.3
-
135
-
-
77954176171
-
An animal model of recognition memory and medial temporal lobe amnesia: History and current issues
-
Clark, R.E.; Squire, L.R. An animal model of recognition memory and medial temporal lobe amnesia: History and current issues. Neuropsychologia, 2010, 48, 2234-2244.
-
(2010)
Neuropsychologia
, vol.48
, pp. 2234-2244
-
-
Clark, R.E.1
Squire, L.R.2
-
136
-
-
64249168387
-
Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia
-
Young, J.W.; Powell, S.; Risbrough, V.; Marston, H.M.; Geyer, M.A. Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol. Ther., 2009, 122(2), 150-202.
-
(2009)
Pharmacol. Ther
, vol.122
, Issue.2
, pp. 150-202
-
-
Young, J.W.1
Powell, S.2
Risbrough, V.3
Marston, H.M.4
Geyer, M.A.5
-
137
-
-
34247574175
-
The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
-
Dere, E.; Huston, J.P.; De Souza Silva, M.A. The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci. Biobehav. Rev., 2007, 31(5), 673-704.
-
(2007)
Neurosci. Biobehav. Rev
, vol.31
, Issue.5
, pp. 673-704
-
-
Dere, E.1
Huston, J.P.2
de Souza Silva, M.A.3
-
138
-
-
34548621479
-
Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat
-
Grayson, B.I.; Idris, N.F.; Neill, J.C. Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat. Behav. Brain Res., 2007, 184(1), 31-38.
-
(2007)
Behav. Brain Res
, vol.184
, Issue.1
, pp. 31-38
-
-
Grayson, B.I.1
Idris, N.F.2
Neill, J.C.3
-
139
-
-
27744572308
-
Phencyclidineinduced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol
-
Hashimoto, K.; Fujita, Y.; Shimizu, E.; Iyo, M. Phencyclidineinduced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol. Eur. J. Pharmacol., 2005, 519, 114-117.
-
(2005)
Eur. J. Pharmacol
, vol.519
, pp. 114-117
-
-
Hashimoto, K.1
Fujita, Y.2
Shimizu, E.3
Iyo, M.4
-
140
-
-
59449096993
-
Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors
-
Nagai, T.; Murai, R.; Matsui, K.; Kamei, H.; Noda, Y.; Furukawa, H.; Nabeshima, T. Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors. Psychopharmacology, 2009, 202(1/3), 315-328.
-
(2009)
Psychopharmacology
, vol.202
, Issue.1-3
, pp. 315-328
-
-
Nagai, T.1
Murai, R.2
Matsui, K.3
Kamei, H.4
Noda, Y.5
Furukawa, H.6
Nabeshima, T.7
-
141
-
-
42749092601
-
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: Role of serotonin 5-HT1A receptors
-
Hagiwara, H.; Fujita, Y.; Ishima, T.; Kunitachi, S.; Shirayama, Y.; Iyo, M.; Hashimoto, K. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: role of serotonin 5-HT1A receptors. Eur. Neuropsychopharmacol., 2008, 18(6), 448-454.
-
(2008)
Eur. Neuropsychopharmacol
, vol.18
, Issue.6
, pp. 448-454
-
-
Hagiwara, H.1
Fujita, Y.2
Ishima, T.3
Kunitachi, S.4
Shirayama, Y.5
Iyo, M.6
Hashimoto, K.7
-
142
-
-
77951883850
-
Effect of pretreatment with risperidone on phencyclidine- induced disruptions in object recognition memory and prefrontal cortex parvalbumin immunoreactivity in the rat
-
McKibben, C.E.; Jenkins, T.A.; Adams, H.N.; Harte, M.K.; Reynolds, G.P. Effect of pretreatment with risperidone on phencyclidine- induced disruptions in object recognition memory and prefrontal cortex parvalbumin immunoreactivity in the rat. Behav. Brain Res., 2010, 208(1), 132-136.
-
(2010)
Behav. Brain Res
, vol.208
, Issue.1
, pp. 132-136
-
-
McKibben, C.E.1
Jenkins, T.A.2
Adams, H.N.3
Harte, M.K.4
Reynolds, G.P.5
-
143
-
-
12344277597
-
Cognitive improvement in schizophrenic patients does notrequire a serotonergic mechanism: Randomized controlled trial of olanzapine vs amisulpride
-
Wagner, M.; Quednow, B.B.; Westheide, J.; Schlaepfer, T.E.; Maier, W.; Kühn, K.U. Cognitive improvement in schizophrenic patients does notrequire a serotonergic mechanism: randomized controlled trial of olanzapine vs amisulpride. Neuropsychopharmacol., 2005, 30, 381-390.
-
(2005)
Neuropsychopharmacol
, vol.30
, pp. 381-390
-
-
Wagner, M.1
Quednow, B.B.2
Westheide, J.3
Schlaepfer, T.E.4
Maier, W.5
Kühn, K.U.6
-
144
-
-
0033019791
-
Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens
-
Kuroki, T.; Meltzer, H.Y.; Ichikawa, J. Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens. J. Pharmacol. Exp. Ther., 1999, 288(2), 774-781.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.288
, Issue.2
, pp. 774-781
-
-
Kuroki, T.1
Meltzer, H.Y.2
Ichikawa, J.3
-
145
-
-
0036711059
-
SR46349-B, a 5-HT (2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens
-
Bonaccorso, S.; Meltzer, H.Y.; Li, Z.; Dai, J.; Alboszta, A.R.; Ichikawa, J. SR46349-B, a 5-HT (2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Neuropsychopharmacol., 2002, 27, 430-441,
-
(2002)
Neuropsychopharmacol
, vol.27
, pp. 430-441
-
-
Bonaccorso, S.1
Meltzer, H.Y.2
Li, Z.3
Dai, J.4
Alboszta, A.R.5
Ichikawa, J.6
-
146
-
-
0031007902
-
Selective action of acute systemic clozapine on acetylcholine release in the rat prefrontal cortex by reference to the nucleus accumbens and striatum
-
Parada, M.A.; Hernandez, L.; Puig de Parada, M.; Rada, P.; Murzi, E. Selective action of acute systemic clozapine on acetylcholine release in the rat prefrontal cortex by reference to the nucleus accumbens and striatum. J. Pharmacol. Exp. Ther., 1997, 281, 582-588.
-
(1997)
J. Pharmacol. Exp. Ther
, vol.281
, pp. 582-588
-
-
Parada, M.A.1
Hernandez, L.2
de Puig Parada, M.3
Rada, P.4
Murzi, E.5
-
147
-
-
0037195552
-
Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: Role of 5-HT1A receptor agonism
-
Ichikawa, J.; Li, Z.; Dai, J.; Meltzer, H.Y. Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism. Brain Res., 2002a, 956(2), 349-357.
-
(2002)
Brain Res
, vol.956
, Issue.2
, pp. 349-357
-
-
Ichikawa, J.1
Li, Z.2
Dai, J.3
Meltzer, H.Y.4
-
148
-
-
0036201186
-
Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat
-
Shirazi-Southall, S.; Rodriguez, D.E.; Nomikos, G.G. Effects of typical and atypical antipsychotics and receptor selective compounds on acetylcholine efflux in the hippocampus of the rat. Neuropsychopharmacol., 2002, 26(5), 583-594.
-
(2002)
Neuropsychopharmacol
, vol.26
, Issue.5
, pp. 583-594
-
-
Shirazi-Southall, S.1
Rodriguez, D.E.2
Nomikos, G.G.3
-
149
-
-
70350408714
-
Effects of quetiapine on phencyclidine-induced cognitive deficits in mice: A possible role of alpha1-adrenoceptors
-
Tanibuchi, Y.; Fujita, Y.; Kohno, M.; Ishima, T.; Takatsu, Y.; Iyo, M.; Hashimoto, K. Effects of quetiapine on phencyclidine-induced cognitive deficits in mice: a possible role of alpha1-adrenoceptors. Eur. Neuropsychopharmacol., 2009, 19(12), 861-867.
-
(2009)
Eur. Neuropsychopharmacol
, vol.19
, Issue.12
, pp. 861-867
-
-
Tanibuchi, Y.1
Fujita, Y.2
Kohno, M.3
Ishima, T.4
Takatsu, Y.5
Iyo, M.6
Hashimoto, K.7
-
150
-
-
72649104250
-
Sertindole improves sub-chronic PCPinduced reversal learning and episodic memory deficits in rodents: Involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms
-
Idris, N.; Neill, J.; Grayson, B.; Bang-Andersen, B.; Witten, L.M.; Brennum, L.T.; Arnt, J. Sertindole improves sub-chronic PCPinduced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms. Psychopharmacology, 2010, 208(1), 23-36.
-
(2010)
Psychopharmacology
, vol.208
, Issue.1
, pp. 23-36
-
-
Idris, N.1
Neill, J.2
Grayson, B.3
Bang-Andersen, B.4
Witten, L.M.5
Brennum, L.T.6
Arnt, J.7
-
151
-
-
36049021794
-
D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats
-
Karasawa, J.; Hashimoto, K.; Chaki, S. D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats. Behav. Brain Res., 2008, 186(1), 78-83.
-
(2008)
Behav. Brain Res
, vol.186
, Issue.1
, pp. 78-83
-
-
Karasawa, J.1
Hashimoto, K.2
Chaki, S.3
-
152
-
-
82955198514
-
Interaction of mGluR 2/3 agonism with clozapine and lurasidone to restore novel object recognition in phencyclidine-treated rats
-
Horiguchi, M.; Huang, M.; Meltzer, H.Y: Interaction of mGluR 2/3 agonism with clozapine and lurasidone to restore novel object recognition in phencyclidine-treated rats. Psychopharmacology, 2011, 217(1), 13-24.
-
(2011)
Psychopharmacology
, vol.217
, Issue.1
, pp. 13-24
-
-
Horiguchi, M.1
Huang, M.2
Meltzer, H.Y.3
-
153
-
-
0030431577
-
Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile
-
Kehne, J.H.; Baron, B.M.; Carr, A.A.; Chaney, S.F.; Elands, J.; Feldman, D.J.; Frank, R.A.; van Giersbergen, P.L.; McCloskey, T.C.; Johnson, M.P.; McCarty, D.R.; Poirot, M.; Senyah, Y.; Siegel, B.W.; Widmaier, C: Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile. J. Pharmacol. Exp. Ther., 1996, 277(2), 968-981.
-
(1996)
J. Pharmacol. Exp. Ther
, vol.277
, Issue.2
, pp. 968-981
-
-
Kehne, J.H.1
Baron, B.M.2
Carr, A.A.3
Chaney, S.F.4
Elands, J.5
Feldman, D.J.6
Frank, R.A.7
van Giersbergen, P.L.8
McCloskey, T.C.9
Johnson, M.P.10
McCarty, D.R.11
Poirot, M.12
Senyah, Y.13
Siegel, B.W.14
Widmaier, C.15
-
154
-
-
0031800006
-
M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice
-
Wang, R.Y.; Liang, X: M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice. Neuropsychopharmacology, 1995, 19(1), 74-85.
-
(1995)
Neuropsychopharmacology
, vol.19
, Issue.1
, pp. 74-85
-
-
Wang, R.Y.1
Liang, X.2
-
155
-
-
84862598929
-
5-HT7 receptor antagonism contributes to the ability of atypical antipsychotic drugs, including lurasidone and amisulpride, to reverse the phencyclidine (PCP)-induced deficit in novel object recognition in rats
-
Horiguchi, M.; Meltzer, H.Y: 5-HT7 receptor antagonism contributes to the ability of atypical antipsychotic drugs, including lurasidone and amisulpride, to reverse the phencyclidine (PCP)-induced deficit in novel object recognition in rats. Abs. Am. College Neuropsychopharmacol., 2010, 338(2),605-614
-
(2010)
Abs. Am. College Neuropsychopharmacol
, vol.338
, Issue.2
, pp. 605-614
-
-
Horiguchi, M.1
Meltzer, H.Y.2
-
156
-
-
77649234391
-
Antagonism at serotonin 5-HT(2A) receptors modulates functional activity of frontohippocampal circuit
-
Gozzi, A.; Crestan, V.; Turrini, G.; Clemens, M.; Bifone, A. Antagonism at serotonin 5-HT(2A) receptors modulates functional activity of frontohippocampal circuit. Psychopharmacology (Berl.), 2010, 209(1), 37-50.
-
(2010)
Psychopharmacology (Berl.)
, vol.209
, Issue.1
, pp. 37-50
-
-
Gozzi, A.1
Crestan, V.2
Turrini, G.3
Clemens, M.4
Bifone, A.5
-
157
-
-
20444398445
-
Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule- dependent mechanism
-
Yuen, E.Y.; Jiang, Q.; Chen, P.; Gu, Z.; Feng, J.; Yan, Z: Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule- dependent mechanism. J. Neurosci., 2005, 25(23), 5488-5501.
-
(2005)
J. Neurosci
, vol.25
, Issue.23
, pp. 5488-5501
-
-
Yuen, E.Y.1
Jiang, Q.2
Chen, P.3
Gu, Z.4
Feng, J.5
Yan, Z.6
-
158
-
-
40449139964
-
Identification of a serotonin/glutamate receptor complex implicated in psychosis
-
González-Maeso, J.; Ang, R.L.; Yuen, T.; Chan, P.; Weisstaub, N.V; López-Giménez, J.F.; Zhou, M.; Okawa, Y.; Callado, L.F.; Milligan, G.; Gingrich, J.A.; Filizola, M.; Meana, J.J.; Sealfon, S.C: Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature, 2008, 452(7183), 93-97.
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 93-97
-
-
González-Maeso, J.1
Ang, R.L.2
Yuen, T.3
Chan, P.4
Weisstaub, N.V.5
López-Giménez, J.F.6
Zhou, M.7
Okawa, Y.8
Callado, L.F.9
Milligan, G.10
Gingrich, J.A.11
Filizola, M.12
Meana, J.J.13
Sealfon, S.C.14
-
159
-
-
0033797463
-
Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors
-
Gewirtz, J.C.; Marek, G.J: Behavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors. Neuropsychopharmacology, 2000, 23(5), 569-576.
-
(2000)
Neuropsychopharmacology
, vol.23
, Issue.5
, pp. 569-576
-
-
Gewirtz, J.C.1
Marek, G.J.2
-
160
-
-
0033981186
-
Physiological antagonism between 5- hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex
-
Marek, G.J.; Wright, R.A.; Schoepp, D.D.; Monn, J.A.; Aghajanian, G.K: Physiological antagonism between 5- hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex. J. Pharmacol. Exp. Ther., 2000, 292(1), 76-87.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.292
, Issue.1
, pp. 76-87
-
-
Marek, G.J.1
Wright, R.A.2
Schoepp, D.D.3
Monn, J.A.4
Aghajanian, G.K.5
-
161
-
-
0032848507
-
The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats
-
Cartmell, J.; Monn, J.A.; Schoepp, D.D. The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats. J. Pharmacol. Exp. Ther., 1999, 291(1), 161-170.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.291
, Issue.1
, pp. 161-170
-
-
Cartmell, J.1
Monn, J.A.2
Schoepp, D.D.3
-
162
-
-
0036894693
-
The group II metabotropic glutamate receptor agonist (-)-2-oxa-4-aminobicyclo[3.1.0]-hexane-4,6-dicarboxylate (LY379268) and clozapine reverse phencyclidineinduced behaviors in monoamine-depleted rats
-
Swanson, C.J.; Schoepp, D.D: The group II metabotropic glutamate receptor agonist (-)-2-oxa-4-aminobicyclo[3.1.0]-hexane-4,6-dicarboxylate (LY379268) and clozapine reverse phencyclidineinduced behaviors in monoamine-depleted rats. J. Pharmacol. Exp. Ther., 2002, 303, 919-927.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.303
, pp. 919-927
-
-
Swanson, C.J.1
Schoepp, D.D.2
-
163
-
-
0022483616
-
Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites
-
Hoyer, D.; Pazos, A.; Probst, A.; Palacios, J.M: Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites. Brain Res., 1986, 376(1), 85-96.
-
(1986)
Brain Res
, vol.376
, Issue.1
, pp. 85-96
-
-
Hoyer, D.1
Pazos, A.2
Probst, A.3
Palacios, J.M.4
-
165
-
-
50149092020
-
The role of 5-HT(1A) receptors in learning and memory
-
Ogren, S.O.; Eriksson, T.M.; Elvander-Tottie, E.; D'Addario, C.; Ekström, J.C.; Svenningsson, P.; Meister, B.; Kehr, J.; Stiedl, O: The role of 5-HT(1A) receptors in learning and memory. Behav. Brain Res., 2008, 195(1), 54-77.
-
(2008)
Behav. Brain Res
, vol.195
, Issue.1
, pp. 54-77
-
-
Ogren, S.O.1
Eriksson, T.M.2
Elvander-Tottie, E.3
D'Addario, C.4
Ekström, J.C.5
Svenningsson, P.6
Meister, B.7
Kehr, J.8
Stiedl, O.9
-
166
-
-
0034745153
-
The 5-HT1A receptor in schizophrenia: A promising target for novel atypical neuroleptics?
-
Bantick, R.A.; Deakin, J.F.; Grasby, P.M: The 5-HT1A receptor in schizophrenia: a promising target for novel atypical neuroleptics? J. Psychopharmacol., 2001, 15(1), 37-46.
-
(2001)
J. Psychopharmacol
, vol.15
, Issue.1
, pp. 37-46
-
-
Bantick, R.A.1
Deakin, J.F.2
Grasby, P.M.3
-
167
-
-
0030858125
-
Functional and anatomical aspects of prefrontal pathology in schizophrenia
-
Goldman-Rakic, P.S.; Selemon, L.D: Functional and anatomical aspects of prefrontal pathology in schizophrenia. Schizophr. Bull., 1997, 23(3), 437-458.
-
(1997)
Schizophr. Bull
, vol.23
, Issue.3
, pp. 437-458
-
-
Goldman-Rakic, P.S.1
Selemon, L.D.2
-
168
-
-
47749153338
-
Activation of 5- HT2A/C receptors counteracts 5-HT1A regulation of n-methyl-Daspartate receptor channels in pyramidal neurons of prefrontal cortex
-
Yuen, E.Y.; Jiang, Q.; Chen, P.; Feng, J.; Yan, Z: Activation of 5- HT2A/C receptors counteracts 5-HT1A regulation of n-methyl-Daspartate receptor channels in pyramidal neurons of prefrontal cortex. J. Biol. Chem., 2008, 283(25), 17194-17204.
-
(2008)
J. Biol. Chem
, vol.283
, Issue.25
, pp. 17194-17204
-
-
Yuen, E.Y.1
Jiang, Q.2
Chen, P.3
Feng, J.4
Yan, Z.5
-
169
-
-
0034030291
-
Effect of adjunctive treatment with serotonin- 1A agonist tandospirone on memory functions in schizophrenia
-
Sumiyoshi, T.; Matsui, M.; Yamashita, I.; Nohara, S.; Uehara, T.; Kurachi, M.; Meltzer, H.Y: Effect of adjunctive treatment with serotonin- 1A agonist tandospirone on memory functions in schizophrenia. J. Clin. Psychopharmacol., 2000, 20(3), 386-388.
-
(2000)
J. Clin. Psychopharmacol
, vol.20
, Issue.3
, pp. 386-388
-
-
Sumiyoshi, T.1
Matsui, M.2
Yamashita, I.3
Nohara, S.4
Uehara, T.5
Kurachi, M.6
Meltzer, H.Y.7
-
170
-
-
0034810016
-
Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment
-
Sumiyoshi, T.; Matsui, M.; Nohara, S.; Yamashita, I.; Kurachi, M.; Sumiyoshi, C.; Jayathilake, K.; Meltzer, H.Y: Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment. Am. J. Psychiatry, 2001a, 158(10), 1722-1725.
-
(2001)
Am. J. Psychiatry
, vol.158
, Issue.10
, pp. 1722-1725
-
-
Sumiyoshi, T.1
Matsui, M.2
Nohara, S.3
Yamashita, I.4
Kurachi, M.5
Sumiyoshi, C.6
Jayathilake, K.7
Meltzer, H.Y.8
-
171
-
-
0035873389
-
The effect of tandospirone, a serotonin(1A) agonist, on memory function in schizophrenia
-
Sumiyoshi, T.; Matsui, M.; Yamashita, I.; Nohara, S.; Kurachi, M.; Uehara, T.; Sumiyoshi, S.; Sumiyoshi, C.; Meltzer, H.Y: The effect of tandospirone, a serotonin(1A) agonist, on memory function in schizophrenia. Biol. Psychiatry, 2001b, 49(10), 861-868.
-
(2001)
Biol. Psychiatry
, vol.49
, Issue.10
, pp. 861-868
-
-
Sumiyoshi, T.1
Matsui, M.2
Yamashita, I.3
Nohara, S.4
Kurachi, M.5
Uehara, T.6
Sumiyoshi, S.7
Sumiyoshi, C.8
Meltzer, H.Y.9
-
172
-
-
0029560673
-
Effects of tandospirone on second messenger systems and neurotransmitter release in the rat brain
-
Tanaka, H.; Tatsuno, T.; Shimizu, H.; Hirose, A.; Kumasaka, Y.; Nakamura, M: Effects of tandospirone on second messenger systems and neurotransmitter release in the rat brain. Gen. Pharmacol., 1995, 26(8), 1765-1772.
-
(1995)
Gen. Pharmacol
, vol.26
, Issue.8
, pp. 1765-1772
-
-
Tanaka, H.1
Tatsuno, T.2
Shimizu, H.3
Hirose, A.4
Kumasaka, Y.5
Nakamura, M.6
-
173
-
-
68849110040
-
Subchronic effects of phencyclidine on dopamine and serotonin receptors: Implications for schizophrenia
-
Choi, Y.K.; Snigdha, S.; Shahid, M.; Neill, J.C.; Tarazi, F.I: Subchronic effects of phencyclidine on dopamine and serotonin receptors: implications for schizophrenia. J. Mol. Neurosci., 2009, 38(3), 227-235.
-
(2009)
J. Mol. Neurosci
, vol.38
, Issue.3
, pp. 227-235
-
-
Choi, Y.K.1
Snigdha, S.2
Shahid, M.3
Neill, J.C.4
Tarazi, F.I.5
-
174
-
-
0032817311
-
5HT antagonists attenuate MK801-impaired radial arm maze performance in rats
-
Boast, C.; Bartolomeo, A.C.; Morris, H.; Moyer, J.A: 5HT antagonists attenuate MK801-impaired radial arm maze performance in rats. Neurobiol. Learn Mem., 1999, 71(3), 259-271.
-
(1999)
Neurobiol. Learn Mem
, vol.71
, Issue.3
, pp. 259-271
-
-
Boast, C.1
Bartolomeo, A.C.2
Morris, H.3
Moyer, J.A.4
-
175
-
-
0043162028
-
The 5-HT 1A receptor antagonist WAY 100635 improves rats performance in different models of amnesia evaluated by the object recognition task
-
Pitsikas, N.; Rigamonti, A.E.; Cella, S.G.; Muller, E.E: The 5-HT 1A receptor antagonist WAY 100635 improves rats performance in different models of amnesia evaluated by the object recognition task. Brain Res., 2003, 983(1/2), 215-222.
-
(2003)
Brain Res
, vol.983
, Issue.1-2
, pp. 215-222
-
-
Pitsikas, N.1
Rigamonti, A.E.2
Cella, S.G.3
Muller, E.E.4
-
176
-
-
41149099114
-
Correlating efficacy in rodent cognition models with in vivo 5- hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane carboxamide (WAY-101405)
-
Hirst, W.D.; Andree, T.H.; Aschmies, S.; Childers, W.E.; Comery, T.A.; Dawson, L.A.; Day, M.; Feingold, I.B.; Grauer, S.M.; Harrison, B.L.; Hughes, Z.A.; Kao, J.; Kelly, M.G.; van der Lee, H.; Rosenzweig-Lipson, S.; Saab, A.L.; Smith, D.L.; Sullivan, K.; Rizzo, S.J.; Tio, C.; Zhang, M.Y.; Schechter, L.E: Correlating efficacy in rodent cognition models with in vivo 5- hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane carboxamide (WAY-101405). J. Pharmacol. Exp. Ther., 2008, 325(1), 134-145.
-
(2008)
J. Pharmacol. Exp. Ther
, vol.325
, Issue.1
, pp. 134-145
-
-
Hirst, W.D.1
Andree, T.H.2
Aschmies, S.3
Childers, W.E.4
Comery, T.A.5
Dawson, L.A.6
Day, M.7
Feingold, I.B.8
Grauer, S.M.9
Harrison, B.L.10
Hughes, Z.A.11
Kao, J.12
Kelly, M.G.13
van der Lee, H.14
Rosenzweig-Lipson, S.15
Saab, A.L.16
Smith, D.L.17
Sullivan, K.18
Rizzo, S.J.19
Tio, C.20
Zhang, M.Y.21
Schechter, L.E.22
more..
-
177
-
-
0035336926
-
Role of 5- HT(2C) receptors in the control of central dopamine function
-
Di Matteo, V.; de Blasi, A.; Di Giulio, C.; Esposito, E: Role of 5- HT(2C) receptors in the control of central dopamine function. Trends Pharmacol. Sci., 2001, 22(5), 229-232.
-
(2001)
Trends Pharmacol. Sci
, vol.22
, Issue.5
, pp. 229-232
-
-
Di Matteo, V.1
de Blasi, A.2
Di Giulio, C.3
Esposito, E.4
-
178
-
-
20944441963
-
WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity
-
Dunlop, J.; Sabb, A.L.; Mazandarani, H.; Zhang, J.; Kalgaonker, S.; Shukhina, E.; Sukoff, S.; Vogel, R.L.; Stack, G.; Schechter, L.; Harrison, B.L.; Rosenzweig-Lipson, S: WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity. J. Pharmacol. Exp. Ther., 2005, 313(2), 862-869.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.313
, Issue.2
, pp. 862-869
-
-
Dunlop, J.1
Sabb, A.L.2
Mazandarani, H.3
Zhang, J.4
Kalgaonker, S.5
Shukhina, E.6
Sukoff, S.7
Vogel, R.L.8
Stack, G.9
Schechter, L.10
Harrison, B.L.11
Rosenzweig-Lipson, S.12
-
179
-
-
67349201388
-
WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics
-
Grauer, S.M.; Graf, R.; Navarra, R.; Sung, A.; Logue, S.F.; Stack, G.; Huselton, C.; Liu, Z.; Comery, T.A.; Marquis, K.L.; Rosenzweig-Lipson, S: WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics. Psychopharmacology, 2009, 204(1), 37-48.
-
(2009)
Psychopharmacology
, vol.204
, Issue.1
, pp. 37-48
-
-
Grauer, S.M.1
Graf, R.2
Navarra, R.3
Sung, A.4
Logue, S.F.5
Stack, G.6
Huselton, C.7
Liu, Z.8
Comery, T.A.9
Marquis, K.L.10
Rosenzweig-Lipson, S.11
-
180
-
-
24044450242
-
The 5-HT2C receptor antagonist RO 60-0491 counteracts rats' retention deficits in a recognition memory task
-
Pitsikas, N.; Sakellaridis, N: The 5-HT2C receptor antagonist RO 60-0491 counteracts rats' retention deficits in a recognition memory task. Brain Res., 2005, 1054(2), 200-202.
-
(2005)
Brain Res
, vol.1054
, Issue.2
, pp. 200-202
-
-
Pitsikas, N.1
Sakellaridis, N.2
-
181
-
-
33846327871
-
CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity
-
Siuciak, J.A.; Chapin, D.S.; McCarthy, S.A.; Guanowsky, V.; Brown, J.; Chiang, P.; Marala, R.; Patterson, T.; Seymour, P.A.; Swick, A.; Iredale, P.A: CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity. Neuropharmacology, 2007, 52(2), 279-290.
-
(2007)
Neuropharmacology
, vol.52
, Issue.2
, pp. 279-290
-
-
Siuciak, J.A.1
Chapin, D.S.2
McCarthy, S.A.3
Guanowsky, V.4
Brown, J.5
Chiang, P.6
Marala, R.7
Patterson, T.8
Seymour, P.A.9
Swick, A.10
Iredale, P.A.11
-
182
-
-
0034698794
-
1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists
-
Bromidge, S.M.; Davies, S.; Duckworth, D.M.; Forbes, I.T.; Jones, G.E.; Jones, J.; King, F.D.; Blackburn, T.P.; Holland, V.; Kennett, G.A.; Lightowler, S.; Middlemiss, D.N.; Riley, G.J.; Trail, B.; Wood, M.D: 1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists. Bioorg. Med. Chem. Lett., 2000, 10(16), 1867-1870.
-
(2000)
Bioorg. Med. Chem. Lett
, vol.10
, Issue.16
, pp. 1867-1870
-
-
Bromidge, S.M.1
Davies, S.2
Duckworth, D.M.3
Forbes, I.T.4
Jones, G.E.5
Jones, J.6
King, F.D.7
Blackburn, T.P.8
Holland, V.9
Kennett, G.A.10
Lightowler, S.11
Middlemiss, D.N.12
Riley, G.J.13
Trail, B.14
Wood, M.D.15
-
183
-
-
65049085795
-
D(1)-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia
-
McLean, S.L.; Idris, N.F.; Woolley, M.L.; Neill, J.C: D(1)-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia. Eur. Neuropsychopharmacol., 2009, 19(6), 440-450.
-
(2009)
Eur. Neuropsychopharmacol
, vol.19
, Issue.6
, pp. 440-450
-
-
McLean, S.L.1
Idris, N.F.2
Woolley, M.L.3
Neill, J.C.4
-
184
-
-
0036978223
-
Involvement of 5-HT(2A/2B/2C) receptors on memory formation: Simple agonism, antagonism, or inverse agonism?
-
Meneses, A: Involvement of 5-HT(2A/2B/2C) receptors on memory formation: simple agonism, antagonism, or inverse agonism? Cell. Mol. Neurobiol., 2002, 22(5/6), 675-688.
-
(2002)
Cell. Mol. Neurobiol
, vol.22
, Issue.5-6
, pp. 675-688
-
-
Meneses, A.1
-
185
-
-
33749515078
-
Selective agents for serotonin2C (5- HT2C) receptors
-
Lacivita, E.; Leopoldo, M: Selective agents for serotonin2C (5- HT2C) receptors. Curr. Top. Med. Chem., 2006, 6, 1927-1970.
-
(2006)
Curr. Top. Med. Chem
, vol.6
, pp. 1927-1970
-
-
Lacivita, E.1
Leopoldo, M.2
-
186
-
-
0028896011
-
Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry
-
Ward, R.P.; Hamblin, M.W.; Lachowicz, J.E.; Hoffman, B.J.; Sibley, D.R.; Dorsa, D.M: Localization of serotonin subtype 6 receptor messenger RNA in the rat brain by in situ hybridization histochemistry. Neuroscience, 1995, 64(4), 1105-1111.
-
(1995)
Neuroscience
, vol.64
, Issue.4
, pp. 1105-1111
-
-
Ward, R.P.1
Hamblin, M.W.2
Lachowicz, J.E.3
Hoffman, B.J.4
Sibley, D.R.5
Dorsa, D.M.6
-
187
-
-
0027481384
-
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs
-
Monsma, F.J. Jr.; Shen, Y.; Ward, R.P.; Hamblin, M.W.; Sibley, D.R: Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol. Pharmacol., 1993, 43(3), 320-327.
-
(1993)
Mol. Pharmacol.
, vol.43
, Issue.3
, pp. 320-327
-
-
Monsma Jr., F.J.1
Shen, Y.2
Ward, R.P.3
Hamblin, M.W.4
Sibley, D.R.5
-
188
-
-
13344275875
-
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor
-
Kohen, R.; Metcalf, M.A.; Khan, N.; Druck, T.; Huebner, K.; Lachowicz, J.E.; Meltzer, H.Y.; Sibley, D.R.; Roth, B.L.; Hamblin, M.W: Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. J. Neurochem., 1996, 66(1), 47-56.
-
(1996)
J. Neurochem
, vol.66
, Issue.1
, pp. 47-56
-
-
Kohen, R.1
Metcalf, M.A.2
Khan, N.3
Druck, T.4
Huebner, K.5
Lachowicz, J.E.6
Meltzer, H.Y.7
Sibley, D.R.8
Roth, B.L.9
Hamblin, M.W.10
-
189
-
-
0032007608
-
Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
-
Arnt, J.; Skarsfeldt, T: Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence. Neuropsychopharmacology, 1998, 18, 63-101.
-
(1998)
Neuropsychopharmacology
, vol.18
, pp. 63-101
-
-
Arnt, J.1
Skarsfeldt, T.2
-
190
-
-
0031722106
-
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor
-
Boess, F.G.; Monsma, F.J. Jr.; Sleight, A.J: Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor. J. Neurochem., 1998, 71(5), 2169-2177.
-
(1998)
J. Neurochem
, vol.71
, Issue.5
, pp. 2169-2177
-
-
Boess, F.G.1
Monsma Jr., F.J.2
Sleight, A.J.3
-
191
-
-
39149098130
-
The selective 5-HT(6) receptor antagonist Ro 04-6790 attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801
-
Pitsikas, N.; Zisopoulou, S.; Pappas, I.; Sakellaridis, N: The selective 5-HT(6) receptor antagonist Ro 04-6790 attenuates psychotomimetic effects of the NMDA receptor antagonist MK-801. Behav.Brain Res., 2008, 188(2), 304-309
-
(2008)
Behav.Brain Res
, vol.188
, Issue.2
, pp. 304-309
-
-
Pitsikas, N.1
Zisopoulou, S.2
Pappas, I.3
Sakellaridis, N.4
-
192
-
-
70349564337
-
The 5-HT7 receptor and disorders of the nervous system: An overview
-
Hedlund, P.B: The 5-HT7 receptor and disorders of the nervous system: an overview. Psychopharmacology, 2009, 206(3), 345-354.
-
(2009)
Psychopharmacology
, vol.206
, Issue.3
, pp. 345-354
-
-
Hedlund, P.B.1
-
193
-
-
0027186438
-
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase
-
Plassat, J.L.; Amlaiky, N.; Hen, R: Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol. Pharmacol., 1993, 44(2), 229-236.
-
(1993)
Mol. Pharmacol
, vol.44
, Issue.2
, pp. 229-236
-
-
Plassat, J.L.1
Amlaiky, N.2
Hen, R.3
-
194
-
-
10744226422
-
Autoradiographic distribution of 5- HT7 receptors in the human brain using [3H]mesulergine: Comparison to other mammalian species
-
Martín-Cora, F.J.; Pazos, A: Autoradiographic distribution of 5- HT7 receptors in the human brain using [3H]mesulergine: comparison to other mammalian species. Br. J. Pharmacol., 2004, 141(1), 92-104.
-
(2004)
Br. J. Pharmacol
, vol.141
, Issue.1
, pp. 92-104
-
-
Martín-Cora, F.J.1
Pazos, A.2
-
195
-
-
4344710330
-
Functional, molecular and pharmacological advances in 5-HT7 receptor research
-
Hedlund, P.B.; Sutcliffe, J.G: Functional, molecular and pharmacological advances in 5-HT7 receptor research. Trends Pharmacol. Sci., 2004, 25(9), 481-486.
-
(2004)
Trends Pharmacol. Sci
, vol.25
, Issue.9
, pp. 481-486
-
-
Hedlund, P.B.1
Sutcliffe, J.G.2
-
196
-
-
3042841937
-
5-HT7 receptors
-
Thomas, D.R.; Hagan, J.J: 5-HT7 receptors. Curr. Drug Targets CNS Neurol. Disord., 2004, 3(1), 81-90.
-
(2004)
Curr. Drug Targets CNS Neurol. Disord
, vol.3
, Issue.1
, pp. 81-90
-
-
Thomas, D.R.1
Hagan, J.J.2
-
197
-
-
40549112655
-
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity
-
Galici, R.; Boggs, J.D.; Miller, K.L.; Bonaventure, P.; Atack, J.R: Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity. Behav. Pharmacol., 2008, 19(2), 153-159.
-
(2008)
Behav. Pharmacol
, vol.19
, Issue.2
, pp. 153-159
-
-
Galici, R.1
Boggs, J.D.2
Miller, K.L.3
Bonaventure, P.4
Atack, J.R.5
-
198
-
-
36849071472
-
Inactivation of the 5-HT(7) receptor partially blocks phencyclidine- induced disruption of prepulse inhibition
-
Semenova, S.; Geyer, M.A.; Sutcliffe, J.G.; Markou, A.; Hedlund, P.B: Inactivation of the 5-HT(7) receptor partially blocks phencyclidine- induced disruption of prepulse inhibition. Biol. Psychiatry, 63(1), 98-105.
-
Biol. Psychiatry
, vol.63
, Issue.1
, pp. 98-105
-
-
Semenova, S.1
Geyer, M.A.2
Sutcliffe, J.G.3
Markou, A.4
Hedlund, P.B.5
-
199
-
-
0036121257
-
Effects of the 5-HT(7) receptor antagonist SB-258741 in animal models for schizophrenia
-
Pouzet, B.; Didriksen, M.; Arnt, J: Effects of the 5-HT(7) receptor antagonist SB-258741 in animal models for schizophrenia. Pharmacol. Biochem. Behav., 2002, 71(4), 655-665.
-
(2002)
Pharmacol. Biochem. Behav
, vol.71
, Issue.4
, pp. 655-665
-
-
Pouzet, B.1
Di driksen, M.2
Arnt, J.3
-
200
-
-
67649452096
-
Amisulpride is a potent 5-HT7 antagonist: Re8levance for antidepressant actions in vivo
-
Abbas, A.I.; Hedlund, P.B.; Huang, X.P.; Tran, T.B.; Meltzer, H.Y.; Roth, B.L: Amisulpride is a potent 5-HT7 antagonist: re8levance for antidepressant actions in vivo. Psychopharmacology, 2009, 205(1), 119-128.
-
(2009)
Psychopharmacology
, vol.205
, Issue.1
, pp. 119-128
-
-
Abbas, A.I.1
Hedlund, P.B.2
Huang, X.P.3
Tran, T.B.4
Meltzer, H.Y.5
Roth, B.L.6
-
201
-
-
4444330225
-
Effects of the 5-HT7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task
-
Meneses, A. Effects of the 5-HT7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task. Behav. Brain Res., 2004, 155(2), 275-282.
-
(2004)
Behav. Brain Res
, vol.155
, Issue.2
, pp. 275-282
-
-
Meneses, A.1
-
202
-
-
70349575345
-
Role of 5- HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat
-
McLean, S.L.; Woolley, M.L.; Thomas, D.; Neill, J.C: Role of 5- HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat. Psychopharmacology, 2009b, 206(3), 403-414.
-
(2009)
Psychopharmacology
, vol.206
, Issue.3
, pp. 403-414
-
-
McLean, S.L.1
Woolley, M.L.2
Thomas, D.3
Neill, J.C.4
-
203
-
-
79952484437
-
The role of serotonin in the NMDA receptor antagonist models of psychosis and cognitive impairment
-
Meltzer, H.Y.; Horiguchi, M.; Massey, B.W: The role of serotonin in the NMDA receptor antagonist models of psychosis and cognitive impairment. Psychopharmacology (Berl.), 2011, 213(2/3), 289-305.
-
(2011)
Psychopharmacology (Berl.)
, vol.213
, Issue.2-3
, pp. 289-305
-
-
Meltzer, H.Y.1
Horiguchi, M.2
Massey, B.W.3
|