메뉴 건너뛰기




Volumn 57, Issue 6, 2000, Pages 553-559

A positron emission tomography study of quetiapine in schizophrenia: A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR; PROLACTIN; QUETIAPINE; SEROTONIN 2A RECEPTOR;

EID: 0034091239     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.57.6.553     Document Type: Article
Times cited : (382)

References (42)
  • 1
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • Seeman P, Lee T, Chau-Wong M, Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature. 1976;261:717-719.
    • (1976) Nature , vol.261 , pp. 717-719
    • Seeman, P.1    Lee, T.2    Chau-Wong, M.3    Wong, K.4
  • 2
    • 0031953450 scopus 로고    scopus 로고
    • 2 receptors, yet occupy high levels of these receptors
    • 2 receptors, yet occupy high levels of these receptors. Mol Psychiatry. 1998;3:123-134.
    • (1998) Mol Psychiatry , vol.3 , pp. 123-134
    • Seeman, P.1    Tallerico, T.2
  • 4
    • 0030969323 scopus 로고    scopus 로고
    • In vivo effects on striatal dopamine D-2 receptor binding by the novel atypical antipsychotic drug sertindole: A 1231 IBZM single photon emission tomography (SPET) study
    • Pilowsky LS, O'Connell P, Davies N, Busatto GF, Costa DC, Murray RM, Ell PJ, Kerwin PW. In vivo effects on striatal dopamine D-2 receptor binding by the novel atypical antipsychotic drug sertindole: a 1231 IBZM single photon emission tomography (SPET) study. Psychopharmacology (Berl). 1997;130:152-158.
    • (1997) Psychopharmacology (Berl) , vol.130 , pp. 152-158
    • Pilowsky, L.S.1    O'Connell, P.2    Davies, N.3    Busatto, G.F.4    Costa, D.C.5    Murray, R.M.6    Ell, P.J.7    Kerwin, P.W.8
  • 5
    • 0026718710 scopus 로고
    • 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: Relation to extrapyramidal side effects
    • 2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine: relation to extrapyramidal side effects. Arch Gen Psychiatry. 1992;49:538-544.
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 538-544
    • Farde, L.1    Nordstrom, A.L.2    Wiesel, F.A.3    Pauli, S.4    Halldin, C.5    Sedvall, G.6
  • 6
    • 0032982714 scopus 로고    scopus 로고
    • 2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia
    • 2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. Am J Psychiatry. 1999;156:286-293.
    • (1999) Am J Psychiatry , vol.156 , pp. 286-293
    • Kapur, S.1    Zipursky, R.B.2    Remington, G.3
  • 7
    • 0031948076 scopus 로고    scopus 로고
    • Plasma prolactin and central D-2 receptor occupancy in antipsychotic drug-treated patients
    • Nordstrom AL, Farde L. Plasma prolactin and central D-2 receptor occupancy in antipsychotic drug-treated patients. J Clin Psychopharmacol. 1998;18:305-310.
    • (1998) J Clin Psychopharmacol , vol.18 , pp. 305-310
    • Nordstrom, A.L.1    Farde, L.2
  • 8
    • 0034025771 scopus 로고    scopus 로고
    • 2 occupancy, clinical response, and side effects: A double-blind PET study in first-episode schizophrenia
    • 2 occupancy, clinical response, and side effects: a double-blind PET study in first-episode schizophrenia. Am J Psychiatry. 2000;157:514-520.
    • (2000) Am J Psychiatry , vol.157 , pp. 514-520
    • Kapur, S.1    Zipursky, R.2    Jones, C.3    Remington, G.4    Houle, S.5
  • 9
    • 0024466603 scopus 로고
    • Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin-2 pKi values
    • Meltzer HY, Matsubara S, Lee JC. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin-2 pKi values. J Pharmacol Exp Ther. 1989;251:238-246.
    • (1989) J Pharmacol Exp Ther. , vol.251 , pp. 238-246
    • Meltzer, H.Y.1    Matsubara, S.2    Lee, J.C.3
  • 10
    • 0029988896 scopus 로고    scopus 로고
    • Serotonin-dopamine interaction and its relevance to schizophrenia
    • Kapur S, Remington G. Serotonin-dopamine interaction and its relevance to schizophrenia. Am J Psychiatry. 1996;153:466-476.
    • (1996) Am J Psychiatry , vol.153 , pp. 466-476
    • Kapur, S.1    Remington, G.2
  • 11
    • 0031865389 scopus 로고    scopus 로고
    • For the Amisulpride study group. Amisulpride, and atypical antipsychotic, in the treatment of acute episodes of schizophrenia: A dose-ranging study vs haloperidol
    • Puech A, Fleurot O, Rein W, for the Amisulpride Study Group. Amisulpride, and atypical antipsychotic, in the treatment of acute episodes of schizophrenia: a dose-ranging study vs haloperidol. Acts Psychiatr Scand. 1998;98:65-72.
    • (1998) Acts Psychiatr Scand. , vol.98 , pp. 65-72
    • Puech, A.1    Fleurot, O.2    Rein, W.3
  • 12
    • 0030743114 scopus 로고    scopus 로고
    • Amisulpride compared with standard neuroleptics in acute exacerbations of schizophrenia: Three efficacy studies
    • Freeman HL. Amisulpride compared with standard neuroleptics in acute exacerbations of schizophrenia: three efficacy studies. Int Clin Psychopharmacol. 1997; 12(suppl 2):S11-S17.
    • (1997) Int Clin Psychopharmacol. , vol.12 , Issue.SUPPL. 2
    • Freeman, H.L.1
  • 13
    • 0021251069 scopus 로고
    • Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain
    • Ogren SO, Hall H, Kohler C, Magnusson O, Lindhlom LO, Angeby K, Florvall L. Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain. Eur J Pharmacol. 1984;102:459-474.
    • (1984) Eur J Pharmacol. , vol.102 , pp. 459-474
    • Ogren, S.O.1    Hall, H.2    Kohler, C.3    Magnusson, O.4    Lindhlom, L.O.5    Angeby, K.6    Florvall, L.7
  • 14
    • 0027248858 scopus 로고
    • Seroquel: Biochemical profile of a potential atypical antipsychotic
    • Saller CF, Salama AI. Seroquel: biochemical profile of a potential atypical antipsychotic. Psychopharmacology. 1993;112:285-292.
    • (1993) Psychopharmacology , vol.112 , pp. 285-292
    • Saller, C.F.1    Salama, A.I.2
  • 15
    • 0030920294 scopus 로고    scopus 로고
    • Quetiapine in patients with schizophrenia: A high- and low-dose double-blind comparison with placebo
    • Small JG, Hirsch SR, Arvanitis LA, Miller BG, Link CG. Quetiapine in patients with schizophrenia: a high- and low-dose double-blind comparison with placebo. Arch Gen Psychiatry. 1997;54:549-557.
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 549-557
    • Small, J.G.1    Hirsch, S.R.2    Arvanitis, L.A.3    Miller, B.G.4    Link, C.G.5
  • 16
    • 0030795988 scopus 로고    scopus 로고
    • Multiple fixed doses of "seroquel" (quetiapine) in patients with acute exacerbation of schizophrenia: A comparison with haloperidol and placebo: The seroquel trial 13 study group
    • Arvanitis LA, Miller BG. Multiple fixed doses of "Seroquel" (quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo: the Seroquel Trial 13 Study Group. Biol Psychiatry. 1997;42:233-246.
    • (1997) Biol Psychiatry , vol.42 , pp. 233-246
    • Arvanitis, L.A.1    Miller, B.G.2
  • 17
    • 0030805337 scopus 로고    scopus 로고
    • A comparison of quetiapine and chlorpromazine in the treatment of schizophrenia
    • Peuskens J, Link CGG. A comparison of quetiapine and chlorpromazine in the treatment of schizophrenia. Acta Psychiatr Scand. 1997;96:265-273.
    • (1997) Acta Psychiatr Scand. , vol.96 , pp. 265-273
    • Peuskens, J.1    Link, C.G.G.2
  • 19
    • 0030882188 scopus 로고    scopus 로고
    • Previous treatment as a confounding variable in studies with novel antipsychotics: Two cases of high dopamine-2 receptor occupancy with quetiapine
    • Tauscher J, Kufferle B, Asenbaum S, Brucke T, Kasper S. Previous treatment as a confounding variable in studies with novel antipsychotics: two cases of high dopamine-2 receptor occupancy with quetiapine. Psychopharmacology. 1997; 133:102-105.
    • (1997) Psychopharmacology , vol.133 , pp. 102-105
    • Tauscher, J.1    Kufferle, B.2    Asenbaum, S.3    Brucke, T.4    Kasper, S.5
  • 20
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261-276.
    • (1987) Schizophr Bull. , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 21
    • 0003412410 scopus 로고
    • Rockville, Md: US Dept of Health, Education, and Welfare, National Institute of Mental Health; Publication ADM 76-338
    • Guy W. ECDEU Assessment Manual for Psychopharmacology. Revised. Rockville, Md: US Dept of Health, Education, and Welfare, National Institute of Mental Health; 1976. Publication ADM 76-338.
    • (1976) ECDEU Assessment Manual for Psychopharmacology. Revised
    • Guy, W.1
  • 22
    • 0024358369 scopus 로고
    • A rating scale for drug-induced akathisia
    • Barnes TR. A rating scale for drug-induced akathisia. Br J Psychiatry. 1989;154: 672-676.
    • (1989) Br J Psychiatry , vol.154 , pp. 672-676
    • Barnes, T.R.1
  • 25
    • 0023820533 scopus 로고
    • 18F]setoperone: A new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo
    • 18F]setoperone: a new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo. Eur J Pharmacol. 1988;147:73-82.
    • (1988) Eur J Pharmacol. , vol.147 , pp. 73-82
    • Blin, J.1    Pappata, S.2    Kiyosawa, M.3    Crouzel, C.4    Baron, J.C.5
  • 31
    • 0027887319 scopus 로고
    • Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy of serotonin2 and dopamine2 receptors
    • Stockmeier CA, DiCarlo JJ, Zhang Y, Thompson P, Meltzer HY. Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy of serotonin2 and dopamine2 receptors. J Pharmacol Exp Ther. 1993;266:1374-1384.
    • (1993) J Pharmacol Exp Ther. , vol.266 , pp. 1374-1384
    • Stockmeier, C.A.1    DiCarlo, J.J.2    Zhang, Y.3    Thompson, P.4    Meltzer, H.Y.5
  • 32
    • 0021073925 scopus 로고
    • Neuroleptics have identical potencies in human brain limbic and putamen regions
    • Seeman P, Ulpian C. Neuroleptics have identical potencies in human brain limbic and putamen regions. Eur J Pharmacol. 1983;94:145-148.
    • (1983) Eur J Pharmacol. , vol.94 , pp. 145-148
    • Seeman, P.1    Ulpian, C.2
  • 33
    • 0030609108 scopus 로고    scopus 로고
    • A PET study of [11C]FLB 457 binding to extrastriatal D2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients
    • Farde L, Suhara T, Nyberg S, Karlsson P, Nakashima Y, Hietala J, Halldin C. A PET study of [11C]FLB 457 binding to extrastriatal D2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients. Psychopharmacology (Berl). 1997;133:396-404.
    • (1997) Psychopharmacology (Berl) , vol.133 , pp. 396-404
    • Farde, L.1    Suhara, T.2    Nyberg, S.3    Karlsson, P.4    Nakashima, Y.5    Hietala, J.6    Halldin, C.7
  • 35
    • 0031928090 scopus 로고    scopus 로고
    • Positron emission tomographic analysis of dose-dependent MDL 100,907 binding to 5-hydroxytryptamine-2A receptors in the human brain
    • Andree B, Nyberg S, Ito H, Ginovart N, Brunner F, Jaquet F, Halldin C, Farde L. Positron emission tomographic analysis of dose-dependent MDL 100,907 binding to 5-hydroxytryptamine-2A receptors in the human brain. J Clin Psychopharmacol. 1998;18:317-323.
    • (1998) J Clin Psychopharmacol. , vol.18 , pp. 317-323
    • Andree, B.1    Nyberg, S.2    Ito, H.3    Ginovart, N.4    Brunner, F.5    Jaquet, F.6    Halldin, C.7    Farde, L.8
  • 36
    • 0004028130 scopus 로고    scopus 로고
    • Management decisions on priority pipeline products-MDL 100907
    • Frankfurt/Main, Germany: Hoescht Marion Roussel Global Employee Communications; July 22
    • Report S. Management decisions on priority pipeline products-MDL 100907 [press release]. In: Vision Extra, Vol 4. Frankfurt/Main, Germany: Hoescht Marion Roussel Global Employee Communications; July 22, 1999.
    • (1999) Vision Extra , vol.4
    • Report, S.1
  • 39
    • 0029317806 scopus 로고
    • Cyproheptadine augmentation of haloperidol in chronic schizophrenic patients: A double-blind placebo-controlled study
    • Lee HS, Song DH, Kim JH, Lee YM, Han ES, Yoo KJ. Cyproheptadine augmentation of haloperidol in chronic schizophrenic patients: a double-blind placebo-controlled study. Int Clin Psychopharmacol. 1995;10:67-72.
    • (1995) Int Clin Psychopharmacol. , vol.10 , pp. 67-72
    • Lee, H.S.1    Song, D.H.2    Kim, J.H.3    Lee, Y.M.4    Han, E.S.5    Yoo, K.J.6
  • 40
    • 0028982509 scopus 로고
    • D-2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate
    • Nyberg S, Farde L, Halldin C, Dahl ML, Bertilsson L. D-2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate. Am J Psychiatry. 1995;152:173-178.
    • (1995) Am J Psychiatry , vol.152 , pp. 173-178
    • Nyberg, S.1    Farde, L.2    Halldin, C.3    Dahl, M.L.4    Bertilsson, L.5
  • 41
  • 42
    • 0030568166 scopus 로고    scopus 로고
    • Drug therapy: Schizophrenia
    • Kane JM. Drug therapy: schizophrenia. N Engl J Med. 1996;334:34-41.
    • (1996) N Engl J Med. , vol.334 , pp. 34-41
    • Kane, J.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.