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Volumn 81, Issue , 2012, Pages 737-765

Pluripotency and nuclear reprogramming

Author keywords

embryogenesis; epigenetics; stem cells; transcription factors

Indexed keywords

ACTIVIN; ACTIVIN A; BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR 2; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; SMAD PROTEIN; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; SOMATOMEDIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 3; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA; UNINDEXED DRUG; WNT PROTEIN;

EID: 84861893874     PISSN: 00664154     EISSN: 15454509     Source Type: Book Series    
DOI: 10.1146/annurev-biochem-052709-104948     Document Type: Article
Times cited : (39)

References (200)
  • 1
    • 33644547994 scopus 로고    scopus 로고
    • Trophoblast and hypoblast in the monotreme, marsupial and eutherian mammal: Evolution and origins
    • Selwood L, Johnson MH. 2006. Trophoblast and hypoblast in the monotreme, marsupial and eutherian mammal: evolution and origins. BioEssays 28(2):128-45
    • (2006) Bio Essays , vol.28 , Issue.2 , pp. 128-145
    • Selwood, L.1    Johnson, M.H.2
  • 2
    • 0033593571 scopus 로고    scopus 로고
    • Axis development and early asymmetry inmammals
    • BeddingtonRS, Robertson EJ. 1999. Axis development and early asymmetry inmammals. Cell 96(2):195-209
    • (1999) Cell , vol.96 , Issue.2 , pp. 195-209
    • Beddington, R.S.1    Robertson, E.J.2
  • 3
    • 0017499569 scopus 로고
    • Studies of the developmental potential of 4-and 8-cell stage mouse blastomeres
    • Kelly SJ. 1977. Studies of the developmental potential of 4-and 8-cell stage mouse blastomeres. J. Exp. Zool. 200(3):365-76
    • (1977) J. Exp. Zool. , vol.200 , Issue.3 , pp. 365-376
    • Kelly, S.J.1
  • 4
    • 45949109693 scopus 로고    scopus 로고
    • Mediators of reprogramming: Transcription factors and transitions through mitosis
    • Egli D, Birkhoff G, Eggan K. 2008. Mediators of reprogramming: transcription factors and transitions through mitosis. Nat. Rev. Mol. Cell Biol. 9(7):505-16
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , Issue.7 , pp. 505-516
    • Egli, D.1    Birkhoff, G.2    Eggan, K.3
  • 5
    • 0019435844 scopus 로고
    • The foundation of two distinct cell lineages within the mouse morula
    • Johnson MH, Ziomek CA. 1981. The foundation of two distinct cell lineages within the mouse morula. Cell 24(1):71-80
    • (1981) Cell , vol.24 , Issue.1 , pp. 71-80
    • Johnson, M.H.1    Ziomek, C.A.2
  • 6
    • 0021006238 scopus 로고
    • The legacy from the oocyte and its role in controlling early development of the mouse embryo
    • Pratt HP, Bolton VN, Gudgeon KA. 1983. The legacy from the oocyte and its role in controlling early development of the mouse embryo. Ciba Found. Symp. 98:197-227
    • (1983) Ciba Found. Symp. , vol.98 , pp. 197-227
    • Pratt, H.P.1    Bolton, V.N.2    Gudgeon, K.A.3
  • 7
    • 0025374899 scopus 로고
    • Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule
    • Ozawa M, Ringwald M, Kemler R. 1990. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Natl. Acad. Sci. USA 87(11):4246-50
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , Issue.11 , pp. 4246-4250
    • Ozawa, M.1    Ringwald, M.2    Kemler, R.3
  • 8
    • 66049117813 scopus 로고    scopus 로고
    • Naive and primed pluripotent states
    • Nichols J, Smith A. 2009. Naive and primed pluripotent states. Cell Stem Cell 4(6):487-92
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 487-492
    • Nichols, J.1    Smith, A.2
  • 9
    • 0025155197 scopus 로고
    • Two alkaline phosphatase genes are expressed during early development in the mouse embryo
    • Hahnel AC, Rappolee DA, Millan JL, Manes T, Ziomek CA, et al. 1990. Two alkaline phosphatase genes are expressed during early development in the mouse embryo. Development 110(2):555-64
    • (1990) Development , vol.110 , Issue.2 , pp. 555-564
    • Hahnel, A.C.1    Rappolee, D.A.2    Millan, J.L.3    Manes, T.4    Ziomek, C.A.5
  • 10
    • 0024147379 scopus 로고
    • Multi-lineage 'stem' cells in the mammalian embryo
    • Gardner RL, Beddington RS. 1988. Multi-lineage 'stem' cells in the mammalian embryo. J. Cell Sci. Suppl. 10:11-27
    • (1988) J. Cell Sci. Suppl. , vol.10 , pp. 11-27
    • Gardner, R.L.1    Beddington, R.S.2
  • 11
    • 0023119242 scopus 로고
    • Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
    • Monk M, Boubelik M, Lehnert S. 1987. Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 99(3):371-82
    • (1987) Development , vol.99 , Issue.3 , pp. 371-382
    • Monk, M.1    Boubelik, M.2    Lehnert, S.3
  • 12
    • 0017173282 scopus 로고
    • Changes in the behaviour of teratocarcinoma cells cultivated in vitro
    • Hogan BL. 1976. Changes in the behaviour of teratocarcinoma cells cultivated in vitro. Nature 263(5573):136-37
    • (1976) Nature , vol.263 , Issue.5573 , pp. 136-137
    • Hogan, B.L.1
  • 13
    • 0016174481 scopus 로고
    • The effect of cells transferred into the mouse blastocyst on subsequent development
    • Brinster RL. 1974. The effect of cells transferred into the mouse blastocyst on subsequent development. J. Exp. Med. 140(4):1049-56
    • (1974) J. Exp. Med. , vol.140 , Issue.4 , pp. 1049-1056
    • Brinster, R.L.1
  • 14
    • 0016801524 scopus 로고
    • Fate of teratocarcinoma cells injected into early mouse embryos
    • Papaioannou VE, McBurney MW, Gardner RL, Evans MJ. 1975. Fate of teratocarcinoma cells injected into early mouse embryos. Nature 258(5530):70-73
    • (1975) Nature , vol.258 , Issue.5530 , pp. 70-73
    • Papaioannou, V.E.1    McBurney, M.W.2    Gardner, R.L.3    Evans, M.J.4
  • 15
    • 0032509321 scopus 로고    scopus 로고
    • Promotion of trophoblast stem cell proliferation by FGF4
    • Tanaka S, Kunath T, Hadjantonakis AK, Nagy A, Rossant J. 1998. Promotion of trophoblast stem cell proliferation by FGF4. Science 282(5396):2072-75
    • (1998) Science , vol.282 , Issue.5396 , pp. 2072-2075
    • Tanaka, S.1    Kunath, T.2    Hadjantonakis, A.K.3    Nagy, A.4    Rossant, J.5
  • 16
    • 20244381688 scopus 로고    scopus 로고
    • Imprinted X-inactivation in extraembryonic endoderm cell lines from mouse blastocysts
    • Kunath T, Arnaud D, Uy GD, Okamoto I, Chureau C, et al. 2005. Imprinted X-inactivation in extraembryonic endoderm cell lines from mouse blastocysts. Development 132(7):1649-61
    • (2005) Development , vol.132 , Issue.7 , pp. 1649-1661
    • Kunath, T.1    Arnaud, D.2    Uy, G.D.3    Okamoto, I.4    Chureau, C.5
  • 17
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. 1981. Establishment in culture of pluripotential cells from mouse embryos. Nature 292(5819):154-56
    • (1981) Nature , vol.292 , Issue.5819 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 18
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. 1981. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA 78(12):7634-38
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , Issue.12 , pp. 7634-7638
    • Martin, G.R.1
  • 19
    • 0024245022 scopus 로고
    • Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides
    • Smith AG, Heath JK, Donaldson DD, Wong GG, Moreau J, et al. 1988. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336(6200):688-90
    • (1988) Nature , vol.336 , Issue.6200 , pp. 688-690
    • Smith, A.G.1    Heath, J.K.2    Donaldson, D.D.3    Wong, G.G.4    Moreau, J.5
  • 20
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams RL, Hilton DJ, Pease S, Willson TA, Stewart CL, et al. 1988. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336(6200):684-87
    • (1988) Nature , vol.336 , Issue.6200 , pp. 684-687
    • Williams, R.L.1    Hilton, D.J.2    Pease, S.3    Willson, T.A.4    Stewart, C.L.5
  • 21
    • 35148845584 scopus 로고    scopus 로고
    • Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
    • Meissner A, Wernig M, Jaenisch R. 2007. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat. Biotechnol. 25(10):1177-81
    • (2007) Nat. Biotechnol. , vol.25 , Issue.10 , pp. 1177-1181
    • Meissner, A.1    Wernig, M.2    Jaenisch, R.3
  • 22
    • 33646527782 scopus 로고    scopus 로고
    • Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-Mapk pathway
    • Chazaud C, Yamanaka Y, Pawson T, Rossant J. 2006. Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-Mapk pathway. Dev. Cell 10(5):615-24
    • (2006) Dev. Cell , vol.10 , Issue.5 , pp. 615-624
    • Chazaud, C.1    Yamanaka, Y.2    Pawson, T.3    Rossant, J.4
  • 23
    • 39149122855 scopus 로고    scopus 로고
    • Capturing pluripotency
    • Silva J, Smith A. 2008. Capturing pluripotency. Cell 132(4):532-36
    • (2008) Cell , vol.132 , Issue.4 , pp. 532-536
    • Silva, J.1    Smith, A.2
  • 24
    • 34447528757 scopus 로고    scopus 로고
    • New cell lines from mouse epiblast share defining features with human embryonic stem cells
    • Tesar PJ, Chenoweth JG, Brook FA, DaviesTJ, Evans EP, et al. 2007. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448(7150):196-99
    • (2007) Nature , vol.448 , Issue.7150 , pp. 196-199
    • Tesar, P.J.1    Chenoweth, J.G.2    Brook, F.A.3    Davies, T.J.4    Evans, E.P.5
  • 25
    • 34447527158 scopus 로고    scopus 로고
    • Derivation of pluripotent epiblast stem cells from mammalian embryos
    • Brons IGM, Smithers LE, Trotter MWB, Rugg-Gunn P, Sun B, et al. 2007. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448(7150):191-95
    • (2007) Nature , vol.448 , Issue.7150 , pp. 191-195
    • Igm, B.1    Smithers, L.E.2    Mwb, T.3    Rugg-Gunn, P.4    Sun, B.5
  • 26
    • 0026699762 scopus 로고
    • Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture
    • Matsui Y, Zsebo K, Hogan BL. 1992. Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell 70(5):841-47
    • (1992) Cell , vol.70 , Issue.5 , pp. 841-847
    • Matsui, Y.1    Zsebo, K.2    Hogan, B.L.3
  • 27
    • 0026669014 scopus 로고
    • Long-term proliferation of mouse primordial germ cells in culture
    • Resnick JL, Bixler LS, Cheng L, Donovan PJ. 1992. Long-term proliferation of mouse primordial germ cells in culture. Nature 359(6395):550-51
    • (1992) Nature , vol.359 , Issue.6395 , pp. 550-551
    • Resnick, J.L.1    Bixler, L.S.2    Cheng, L.3    Donovan, P.J.4
  • 29
    • 0025779118 scopus 로고
    • Effects of the steel gene product on mouse primordial germ cells in culture
    • Godin I, Deed R, Cooke J, Zsebo K, Dexter M, Wylie CC. 1991. Effects of the steel gene product on mouse primordial germ cells in culture. Nature 352(6338):807-9
    • (1991) Nature , vol.352 , Issue.6338 , pp. 807-809
    • Godin, I.1    Deed, R.2    Cooke, J.3    Zsebo, K.4    Dexter, M.5    Wylie, C.C.6
  • 30
    • 0033143970 scopus 로고    scopus 로고
    • Reprogramming a somatic nucleus by trans-modification activity in germ cells
    • Surani MA. 1999. Reprogramming a somatic nucleus by trans-modification activity in germ cells. Semin. Cell Dev. Biol. 10(3):273-77
    • (1999) Semin. Cell Dev. Biol. , vol.10 , Issue.3 , pp. 273-277
    • Surani, M.A.1
  • 31
    • 13944262909 scopus 로고    scopus 로고
    • A germ cell origin of embryonic stem cells?
    • Zwaka TP, Thomson JA. 2005. A germ cell origin of embryonic stem cells? Development 132(2):227-33
    • (2005) Development , vol.132 , Issue.2 , pp. 227-233
    • Zwaka, T.P.1    Thomson, J.A.2
  • 32
    • 1842533535 scopus 로고    scopus 로고
    • Spontaneous differentiation of germ cells from human embryonic stem cells in vitro
    • Clark AT, Bodnar MS, Fox M, Rodriquez RT, Abeyta MJ, et al. 2004. Spontaneous differentiation of germ cells from human embryonic stem cells in vitro. Hum. Mol. Genet. 13(7):727-39
    • (2004) Hum. Mol. Genet. , vol.13 , Issue.7 , pp. 727-739
    • Clark, A.T.1    Bodnar, M.S.2    Fox, M.3    Rodriquez, R.T.4    Abeyta, M.J.5
  • 33
  • 34
    • 0346562866 scopus 로고    scopus 로고
    • Derivation of embryonic germ cells and male gametes from embryonic stem cells
    • GeijsenN, Horoschak M, Kim K, Gribnau J, Eggan K, Daley GQ. 2004. Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature 427(6970):148-54
    • (2004) Nature , vol.427 , Issue.6970 , pp. 148-154
    • Geijsen, N.1    Horoschak, M.2    Kim, K.3    Gribnau, J.4    Eggan, K.5    Daley, G.Q.6
  • 35
    • 19944385908 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from neonatal mouse testis
    • Kanatsu-Shinohara M, Inoue K, Lee J, Yoshimoto M, OgonukiN, et al. 2004. Generation of pluripotent stem cells from neonatal mouse testis. Cell 119(7):1001-12
    • (2004) Cell , vol.119 , Issue.7 , pp. 1001-1012
    • Kanatsu-Shinohara, M.1    Inoue, K.2    Lee, J.3    Yoshimoto, M.4    Ogonuki, N.5
  • 36
    • 33646336640 scopus 로고    scopus 로고
    • Pluripotency of spermatogonial stem cells from adult mouse testis
    • Guan K, Nayernia K, Maier LS, Wagner S, Dressel R, et al. 2006. Pluripotency of spermatogonial stem cells from adult mouse testis. Nature 440(7088):1199-203
    • (2006) Nature , vol.440 , Issue.7088 , pp. 1199-1203
    • Guan, K.1    Nayernia, K.2    Maier, L.S.3    Wagner, S.4    Dressel, R.5
  • 37
    • 34548844476 scopus 로고    scopus 로고
    • Generation of functional multipotent adult stem cells from GPR125+ germline progenitors
    • SeandelM, James D, Shmelkov SV, Falciatori I, Kim J, et al. 2007. Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature 449(7160):346-50
    • (2007) Nature , vol.449 , Issue.7160 , pp. 346-350
    • Seandel James M, D.1    Shmelkov, S.V.2    Falciatori, I.3    Kim, J.4
  • 39
    • 25444503012 scopus 로고    scopus 로고
    • Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells
    • Dvorak P, DvorakovaD, Koskova S, Vodinska M, Najvirtova M, et al. 2005. Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells. Stem Cells 23(8):1200-11
    • (2005) Stem Cells , vol.23 , Issue.8 , pp. 1200-1211
    • Dvorak, P.1    Dvorakova, D.2    Koskova, S.3    Vodinska, M.4    Najvirtova, M.5
  • 40
    • 27644486756 scopus 로고    scopus 로고
    • Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
    • Vallier L, Alexander M, Pedersen RA. 2005. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J. Cell Sci. 118(Pt. 19):4495-509
    • (2005) J. Cell Sci. , vol.118 , Issue.PART 19 , pp. 4495-4509
    • Vallier, L.1    Alexander, M.2    Pedersen, R.A.3
  • 41
    • 28444475519 scopus 로고    scopus 로고
    • Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in themaintenance of human embryonic stem cells
    • Pbay A, Wong RCB, Pitson SM, Wolvetang EJ, Peh GS-L, et al. 2005. Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in themaintenance of human embryonic stem cells. Stem Cells 23(10):1541-48
    • (2005) Stem Cells , vol.23 , Issue.10 , pp. 1541-1548
    • Pbay, A.1    Rcb, W.2    Pitson, S.M.3    Wolvetang, E.J.4    Gs-L, P.5
  • 42
    • 34548307176 scopus 로고    scopus 로고
    • IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
    • Bendall SC, Stewart MH, Menendez P, George D, Vijayaragavan K, et al. 2007. IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro. Nature 448(7157):1015-21
    • (2007) Nature , vol.448 , Issue.7157 , pp. 1015-1021
    • Bendall, S.C.1    Stewart, M.H.2    Menendez, P.3    George, D.4    Vijayaragavan, K.5
  • 43
    • 33750977572 scopus 로고    scopus 로고
    • The regulation of self-renewal in human embryonic stem cells
    • Avery S, Inniss K, Moore H. 2006. The regulation of self-renewal in human embryonic stem cells. Stem Cells Dev. 15(5):729-40
    • (2006) Stem Cells Dev. , vol.15 , Issue.5 , pp. 729-740
    • Avery, S.1    Inniss, K.2    Moore, H.3
  • 44
    • 67650096520 scopus 로고    scopus 로고
    • Activin/Nodal signalling maintains pluripotency by controlling Nanog expression
    • Vallier L, Mendjan S, Brown S, Chng Z, Teo A, et al. 2009. Activin/Nodal signalling maintains pluripotency by controlling Nanog expression. Development 136(8):1339-49
    • (2009) Development , vol.136 , Issue.8 , pp. 1339-1349
    • Vallier, L.1    Mendjan, S.2    Brown, S.3    Chng, Z.4    Teo, A.5
  • 45
    • 1442336166 scopus 로고    scopus 로고
    • Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma
    • Clark AT, Rodriguez RT, Bodnar MS, Abeyta MJ, CedarsMI, et al. 2004. Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells 22(2):169-79
    • (2004) Stem Cells , vol.22 , Issue.2 , pp. 169-179
    • Clark, A.T.1    Rodriguez, R.T.2    Bodnar, M.S.3    Abeyta, M.J.4    Cedars, M.I.5
  • 46
    • 66049136895 scopus 로고    scopus 로고
    • Klf4 reverts developmentally programmed restriction of ground state pluripotency
    • Guo G, Yang J, Nichols J, Hall JS, Eyres I, et al. 2009. Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development 136(7):1063-69
    • (2009) Development , vol.136 , Issue.7 , pp. 1063-1069
    • Guo, G.1    Yang, J.2    Nichols, J.3    Hall, J.S.4    Eyres, I.5
  • 47
    • 53049092465 scopus 로고    scopus 로고
    • Dynamic equilibrium and heterogeneity ofmouse pluripotent stem cells with distinct functional and epigenetic states
    • Int. Stem Cell Initiat
    • Hayashi K, Lopes SMCDS, Tang F, Surani MA. 2008. Dynamic equilibrium and heterogeneity ofmouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3(4):391-401.Int. Stem Cell Initiat.
    • (2008) Cell Stem Cell , vol.3 , Issue.4 , pp. 391-401
    • Hayashi, K.1    Lopes, S.M.C.D.S.2    Tang, F.3    Surani, M.A.4
  • 48
    • 34447295350 scopus 로고    scopus 로고
    • Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
    • Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, et al. 2007. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat. Biotechnol. 25(7):803-16
    • (2007) Nat. Biotechnol. , vol.25 , Issue.7 , pp. 803-816
    • Adewumi, O.1    Aflatoonian, B.2    Ahrlund-Richter, L.3    Amit, M.4
  • 49
    • 33846917472 scopus 로고    scopus 로고
    • Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
    • Babaie Y, Herwig R, Greber B, Brink TC, Wruck W, et al. 2007. Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells 25(2):500-10
    • (2007) Stem Cells , vol.25 , Issue.2 , pp. 500-510
    • Babaie, Y.1    Herwig, R.2    Greber, B.3    Brink, T.C.4    Wruck, W.5
  • 50
    • 34147113900 scopus 로고    scopus 로고
    • Ameta-analysis of human embryonic stem cells transcriptome integrated into a Web-based expression atlas
    • Assou S, Le Carrour T, Tondeur S, Strm S, Gabelle A, et al. 2007. Ameta-analysis of human embryonic stem cells transcriptome integrated into a Web-based expression atlas. Stem Cells 25(4):961-73
    • (2007) Stem Cells , vol.25 , Issue.4 , pp. 961-973
    • Assou, S.1    Le Carrour, T.2    Tondeur, S.3    Strm, S.4    Gabelle, A.5
  • 51
    • 77449161605 scopus 로고    scopus 로고
    • Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells
    • Greber B, Wu G, Bernemann C, Joo JY, Han DW, et al. 2010. Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells. Cell Stem Cell 6(3):215-26
    • (2010) Cell Stem Cell , vol.6 , Issue.3 , pp. 215-226
    • Greber, B.1    Wu, G.2    Bernemann, C.3    Joo, J.Y.4    Han, D.W.5
  • 52
    • 1842364873 scopus 로고    scopus 로고
    • Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells
    • Tada M, Tada T, Lefebvre L, Barton SC, Surani MA. 1997. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. EMBO J. 16(21):6510-20
    • (1997) EMBO J. , vol.16 , Issue.21 , pp. 6510-6520
    • Tada, M.1    Tada, T.2    Lefebvre, L.3    Barton, S.C.4    Surani, M.A.5
  • 53
    • 0037041428 scopus 로고    scopus 로고
    • Changing potency by spontaneous fusion
    • Ying Q-L, Nichols J, Evans EP, Smith AG. 2002. Changing potency by spontaneous fusion. Nature 416(6880):545-48
    • (2002) Nature , vol.416 , Issue.6880 , pp. 545-548
    • Ying, Q.-L.1    Nichols, J.2    Evans, E.P.3    Smith, A.G.4
  • 54
    • 0037041427 scopus 로고    scopus 로고
    • Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion
    • Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, et al. 2002. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 416(6880):542-45
    • (2002) Nature , vol.416 , Issue.6880 , pp. 542-545
    • Terada, N.1    Hamazaki, T.2    Oka, M.3    Hoki, M.4    Mastalerz, D.M.5
  • 55
    • 0035797898 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
    • Tada M, Takahama Y, Abe K, Nakatsuji N, Tada T. 2001. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr. Biol. 11(19):1553-58
    • (2001) Curr. Biol. , vol.11 , Issue.19 , pp. 1553-1558
    • Tada, M.1    Takahama, Y.2    Abe, K.3    Nakatsuji, N.4    Tada, T.5
  • 56
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4):663-76
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 57
    • 70350536767 scopus 로고    scopus 로고
    • A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog
    • Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, et al. 2009. A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 5(5):491-503
    • (2009) Cell Stem Cell , vol.5 , Issue.5 , pp. 491-503
    • Ichida, J.K.1    Blanchard, J.2    Lam, K.3    Son, E.Y.4    Chung, J.E.5
  • 58
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, et al. 2007. Induced pluripotent stem cell lines derived from human somatic cells. Science 318(5858):1917-20
    • (2007) Science , vol.318 , Issue.5858 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3    Antosiewicz-Bourget, J.4    Frane, J.L.5
  • 59
    • 41949098160 scopus 로고    scopus 로고
    • Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
    • Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, et al. 2008. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133(2):250-64
    • (2008) Cell , vol.133 , Issue.2 , pp. 250-264
    • Hanna, J.1    Markoulaki, S.2    Schorderet, P.3    Carey, B.W.4    Beard, C.5
  • 60
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, et al. 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458(7239):766-70
    • (2009) Nature , vol.458 , Issue.7239 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3    Desai, R.4    Mileikovsky, M.5
  • 61
    • 58549096370 scopus 로고    scopus 로고
    • Reprogramming of murine and human somatic cells using a single polycistronic vector
    • Carey BW, Markoulaki S, Hanna J, Saha K, Gao Q, et al. 2009. Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc. Natl. Acad. Sci. USA 106(1):157-62
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.1 , pp. 157-162
    • Carey, B.W.1    Markoulaki, S.2    Hanna, J.3    Saha, K.4    Gao, Q.5
  • 62
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K. 2008. Induced pluripotent stem cells generated without viral integration. Science 322(5903):945-49
    • (2008) Science , vol.322 , Issue.5903 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 63
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S. 2008. Generation of mouse induced pluripotent stem cells without viral vectors. Science 322(5903):949-53
    • (2008) Science , vol.322 , Issue.5903 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 64
    • 78149487692 scopus 로고    scopus 로고
    • Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
    • Hanna JH, Saha K, Jaenisch R. 2010. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 143(4):508-25
    • (2010) Cell , vol.143 , Issue.4 , pp. 508-525
    • Hanna, J.H.1    Saha, K.2    Jaenisch, R.3
  • 65
    • 77956260872 scopus 로고    scopus 로고
    • Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells
    • Guenther MG, Frampton GM, Soldner F, Hockemeyer D, MitalipovaM, et al. 2010. Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells. Cell Stem Cell 7(2):249-57
    • (2010) Cell Stem Cell , vol.7 , Issue.2 , pp. 249-257
    • Guenther, M.G.1    Frampton, G.M.2    Soldner, F.3    Hockemeyer, D.4    Mitalipova, M.5
  • 66
    • 77956247114 scopus 로고    scopus 로고
    • Lab-specific gene expression signatures in pluripotent stem cells
    • Newman AM, Cooper JB. 2010. Lab-specific gene expression signatures in pluripotent stem cells. Cell Stem Cell 7(2):258-62
    • (2010) Cell Stem Cell , vol.7 , Issue.2 , pp. 258-262
    • Newman, A.M.1    Cooper, J.B.2
  • 67
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B, Ng K, Zhao R, et al. 2010. Epigenetic memory in induced pluripotent stem cells. Nature 467(7313):285-90
    • (2010) Nature , vol.467 , Issue.7313 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3    Ng, K.4    Zhao, R.5
  • 68
    • 0021165918 scopus 로고
    • Correct transcription of an immunoglobulin kappa gene requires an upstream fragment containing conserved sequence elements
    • Falkner FG, Zachau HG. 1984. Correct transcription of an immunoglobulin kappa gene requires an upstream fragment containing conserved sequence elements. Nature 310(5972):71-74
    • (1984) Nature , vol.310 , Issue.5972 , pp. 71-74
    • Falkner, F.G.1    Zachau, H.G.2
  • 69
  • 70
    • 0029124988 scopus 로고
    • The POU domain: Versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain
    • Herr W, Cleary MA. 1995. The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Genes Dev. 9(14):1679-93
    • (1995) Genes Dev. , vol.9 , Issue.14 , pp. 1679-1693
    • Herr, W.1    Cleary, M.A.2
  • 71
    • 0346462991 scopus 로고    scopus 로고
    • Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1·Sox2· Hoxb1-DNA ternary transcription factor complex
    • Williams DC Jr, Cai M, Clore GM. 2004. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1·Sox2·Hoxb1-DNA ternary transcription factor complex. J. Biol. Chem. 279(2):1449-57
    • (2004) J. Biol. Chem. , vol.279 , Issue.2 , pp. 1449-1457
    • Williams Jr., D.C.1    Cai, M.2    Clore, G.M.3
  • 72
    • 0342656167 scopus 로고    scopus 로고
    • Characterization of sequence-specific DNA binding by the transcription factor Oct-1
    • Lundbck T, Chang JF, Phillips K, Luisi B, Ladbury JE. 2000. Characterization of sequence-specific DNA binding by the transcription factor Oct-1. Biochemistry 39(25):7570-79
    • (2000) Biochemistry , vol.39 , Issue.25 , pp. 7570-7579
    • Lundbck, T.1    Chang, J.F.2    Phillips, K.3    Luisi, B.4    Ladbury, J.E.5
  • 73
    • 0034612994 scopus 로고    scopus 로고
    • The virtuoso of versatility: POU proteins that flex to fit
    • Phillips K, Luisi B. 2000. The virtuoso of versatility: POU proteins that flex to fit. J. Mol. Biol. 302(5):1023-39
    • (2000) J. Mol. Biol. , vol.302 , Issue.5 , pp. 1023-1039
    • Phillips, K.1    Luisi, B.2
  • 74
    • 0032582513 scopus 로고    scopus 로고
    • Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
    • Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, et al. 1998. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95(3):379-91
    • (1998) Cell , vol.95 , Issue.3 , pp. 379-391
    • Nichols, J.1    Zevnik, B.2    Anastassiadis, K.3    Niwa, H.4    Klewe-Nebenius, D.5
  • 75
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG. 2000. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 24(4):372-76
    • (2000) Nat. Genet. , vol.24 , Issue.4 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 76
    • 79958263080 scopus 로고    scopus 로고
    • Pluripotency factors in embryonic stem cells regulate differentiation into germ layers
    • Thomson M, Liu SJ, Zou L-N, Smith Z, Meissner A, Ramanathan S. 2011. Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Cell 145(6):875-89
    • (2011) Cell , vol.145 , Issue.6 , pp. 875-889
    • Thomson, M.1    Liu, S.J.2    Zou, L.-N.3    Smith, Z.4    Meissner, A.5    Ramanathan, S.6
  • 77
    • 34548587064 scopus 로고    scopus 로고
    • FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment
    • Kunath T, Saba-El-Leil MK, AlmousailleakhM, Wray J, Meloche S, Smith A. 2007. FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development 134(16):2895-902
    • (2007) Development , vol.134 , Issue.16 , pp. 2895-2902
    • Kunath, T.1    Saba-El-Leil, M.K.2    Almousailleakh, M.3    Wray, J.4    Meloche, S.5    Smith, A.6
  • 78
    • 33751092246 scopus 로고    scopus 로고
    • A protein interaction network for pluripotency of embryonic stem cells
    • Wang J, Rao S, Chu J, Shen X, Levasseur DN, et al. 2006. A protein interaction network for pluripotency of embryonic stem cells. Nature 444(7117):364-68
    • (2006) Nature , vol.444 , Issue.7117 , pp. 364-368
    • Wang, J.1    Rao, S.2    Chu, J.3    Shen, X.4    Levasseur, D.N.5
  • 80
    • 44649086468 scopus 로고    scopus 로고
    • Nanog and Oct4 associatewith unique transcriptional repression complexes in embryonic stem cells
    • Liang J, Wan M, ZhangY, Gu P, Xin H, et al. 2008. Nanog and Oct4 associatewith unique transcriptional repression complexes in embryonic stem cells. Nat. Cell Biol. 10(6):731-79
    • (2008) Nat. Cell Biol. , vol.10 , Issue.6 , pp. 731-779
    • Liang, J.1    Wan, M.2    Zhangy Gu, P.3    Xin, H.4
  • 82
    • 34249876564 scopus 로고    scopus 로고
    • Pluripotency governed by SOX2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    • Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, et al. 2007. Pluripotency governed by SOX2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat. Cell Biol. 9(6):625-35
    • (2007) Nat. Cell Biol. , vol.9 , Issue.6 , pp. 625-635
    • Masui, S.1    Nakatake, Y.2    Toyooka, Y.3    Shimosato, D.4    Yagi, R.5
  • 83
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, et al. 2003. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113(5):631-42
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5
  • 84
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers I, Colby D, Robertson M, Nichols J, Lee S, et al. 2003. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113(5):643-55
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5
  • 85
    • 37549002155 scopus 로고    scopus 로고
    • Nanog safeguards pluripotency and mediates germline development
    • Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, et al. 2007. Nanog safeguards pluripotency and mediates germline development. Nature 450(7173):1230-34
    • (2007) Nature , vol.450 , Issue.7173 , pp. 1230-1234
    • Chambers, I.1    Silva, J.2    Colby, D.3    Nichols, J.4    Nijmeijer, B.5
  • 86
    • 33746773659 scopus 로고    scopus 로고
    • Dissecting self-renewal in stem cells with RNA interference
    • Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, et al. 2006. Dissecting self-renewal in stem cells with RNA interference. Nature 442(7102):533-38
    • (2006) Nature , vol.442 , Issue.7102 , pp. 533-538
    • Ivanova, N.1    Dobrin, R.2    Lu, R.3    Kotenko, I.4    Levorse, J.5
  • 87
    • 33747747661 scopus 로고    scopus 로고
    • Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells
    • Wu Q, Chen X, Zhang J, Loh Y-H, Low T-Y, et al. 2006. Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells. J. Biol. Chem. 281(34):24090-94
    • (2006) J. Biol. Chem. , vol.281 , Issue.34 , pp. 24090-24094
    • Wu, Q.1    Chen, X.2    Zhang, J.3    Loh, Y.-H.4    Low, T.-Y.5
  • 88
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. 2005. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122(6):947-56
    • (2005) Cell , vol.122 , Issue.6 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3    Johnstone, S.E.4    Levine, S.S.5
  • 89
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X, Xu H, Yuan P, Fang F, Huss M, et al. 2008. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133(6):1106-17
    • (2008) Cell , vol.133 , Issue.6 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3    Fang, F.4    Huss, M.5
  • 90
    • 33645381936 scopus 로고    scopus 로고
    • TheOct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh Y-H, WuQ, Chew J-L, Vega VB, Zhang W, et al. 2006. TheOct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet. 38(4):431-40
    • (2006) Nat. Genet. , vol.38 , Issue.4 , pp. 431-440
    • Loh, Y.-H.1    Wu, Q.2    Chew, J.-L.3    Vega, V.B.4    Zhang, W.5
  • 92
    • 70350686180 scopus 로고    scopus 로고
    • SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
    • Bilodeau S, KageyMH, Frampton GM, Rahl PB, Young RA. 2009. SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev. 23(21):2484-89
    • (2009) Genes Dev. , vol.23 , Issue.21 , pp. 2484-2489
    • Bilodeau, S.1    Kagey, M.H.2    Frampton, G.M.3    Rahl, P.B.4    Young, R.A.5
  • 93
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, et al. 2006. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441(7091):349-53
    • (2006) Nature , vol.441 , Issue.7091 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3    Brambrink, T.4    Medeiros, L.A.5
  • 94
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by polycomb in human embryonic stem cells
    • LeeTI, JennerRG, BoyerLA, GuentherMG, Levine SS, et al. 2006. Control of developmental regulators by polycomb in human embryonic stem cells. Cell 125(2):301-13
    • (2006) Cell , vol.125 , Issue.2 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5
  • 95
    • 48449084118 scopus 로고    scopus 로고
    • ConnectingmicroRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
    • Marson A, Levine SS, Cole MF, FramptonGM, Brambrink T, et al. 2008. ConnectingmicroRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 134(3):521-33
    • (2008) Cell , vol.134 , Issue.3 , pp. 521-533
    • Marson, A.1    Levine, S.S.2    Cole, M.F.3    Frampton, G.M.4    Brambrink, T.5
  • 96
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini D, Bracken AP, Jensen MR, Lazzerini Denchi E, Helin K. 2004. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23(20):4061-71
    • (2004) EMBO J. , vol.23 , Issue.20 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Lazzerini Denchi, E.4    Helin, K.5
  • 97
    • 54349087788 scopus 로고    scopus 로고
    • Myc's broad reach
    • Eilers M, Eisenman RN. 2008. Myc's broad reach. Genes Dev. 22(20):2755-66
    • (2008) Genes Dev. , vol.22 , Issue.20 , pp. 2755-2766
    • Eilers, M.1    Eisenman, R.N.2
  • 98
    • 16844364151 scopus 로고    scopus 로고
    • LTF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
    • Cartwright P, McLean C, Sheppard A, Rivett D, Jones K, Dalton S. 2005. LTF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 132(5):885-96
    • (2005) Development , vol.132 , Issue.5 , pp. 885-896
    • Cartwright, P.1    McLean, C.2    Sheppard, A.3    Rivett, D.4    Jones, K.5    Dalton, S.6
  • 99
    • 79951893490 scopus 로고    scopus 로고
    • Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency
    • Smith KN, Lim J-M, Wells L, Dalton S. 2011. Myc orchestrates a regulatory network required for the establishment and maintenance of pluripotency. Cell Cycle 10(4):592-97
    • (2011) Cell Cycle , vol.10 , Issue.4 , pp. 592-597
    • Smith, K.N.1    Lim, J.-M.2    Wells, L.3    Dalton, S.4
  • 100
    • 77956214711 scopus 로고    scopus 로고
    • Myc represses primitive endoderm differentiation in pluripotent stem cells
    • Smith KN, Singh AM, Dalton S. 2010. Myc represses primitive endoderm differentiation in pluripotent stem cells. Cell Stem Cell 7(3):343-54
    • (2010) Cell Stem Cell , vol.7 , Issue.3 , pp. 343-354
    • Smith, K.N.1    Singh, A.M.2    Dalton, S.3
  • 101
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • Kim J, Woo AJ, Chu J, Snow JW, Fujiwara Y, et al. 2010. A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell 143(2):313-24
    • (2010) Cell , vol.143 , Issue.2 , pp. 313-324
    • Kim, J.1    Woo, A.J.2    Chu, J.3    Snow, J.W.4    Fujiwara, Y.5
  • 102
    • 70350302617 scopus 로고    scopus 로고
    • Myc-regulated microRNAs attenuate embryonic stem cell differentiation
    • Lin C-H, Jackson AL, Guo J, Linsley PS, Eisenman RN. 2009. Myc-regulated microRNAs attenuate embryonic stem cell differentiation. EMBO J. 28(20):3157-70
    • (2009) EMBO J. , vol.28 , Issue.20 , pp. 3157-3170
    • Lin, C.-H.1    Jackson, A.L.2    Guo, J.3    Linsley, P.S.4    Eisenman, R.N.5
  • 103
    • 84155165037 scopus 로고    scopus 로고
    • Down-regulation of Thanatosassociated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression
    • Nakamura S, Yokota D, Tan L, Nagata Y, Takemura T, et al. 2012. Down-regulation of Thanatosassociated protein 11 by BCR-ABL promotes CML cell proliferation through c-Myc expression. Int. J. Cancer 130(5):1046-59
    • (2012) Int. J. Cancer , vol.130 , Issue.5 , pp. 1046-1059
    • Nakamura, S.1    Yokota, D.2    Tan, L.3    Nagata, Y.4    Takemura, T.5
  • 104
    • 60849086455 scopus 로고    scopus 로고
    • Cell growth suppression by thanatosassociated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc
    • Zhu C-Y, Li C-Y, Li Y, Zhan Y-Q, Li Y-H, et al. 2009. Cell growth suppression by thanatosassociated protein 11(THAP11) is mediated by transcriptional downregulation of c-Myc. Cell Death Differ. 16(3):395-405
    • (2009) Cell Death Differ. , vol.16 , Issue.3 , pp. 395-405
    • Zhu, C.-Y.1    Li, C.-Y.2    Li, Y.3    Zhan, Y.-Q.4    Li, Y.-H.5
  • 105
    • 77954849530 scopus 로고    scopus 로고
    • Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells
    • Dejosez M, Levine SS, Frampton GM, Whyte WA, Stratton SA, et al. 2010. Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells. Genes Dev. 24(14):1479-84
    • (2010) Genes Dev. , vol.24 , Issue.14 , pp. 1479-1484
    • Dejosez, M.1    Levine, S.S.2    Frampton, G.M.3    Whyte, W.A.4    Stratton, S.A.5
  • 106
    • 68549091056 scopus 로고    scopus 로고
    • Ronin and caspases in embryonic stem cells: A new perspective on regulation of the pluripotent state
    • Zwaka TP. 2008. Ronin and caspases in embryonic stem cells: a new perspective on regulation of the pluripotent state. Cold Spring Harb. Symp. Quant. Biol. 73:163-69
    • (2008) Cold Spring Harb. Symp. Quant. Biol. , vol.73 , pp. 163-169
    • Zwaka, T.P.1
  • 107
    • 45449093213 scopus 로고    scopus 로고
    • Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells
    • Dejosez M, Krumenacker JS, Zitur LJ, Passeri M, Chu L-F, et al. 2008. Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell 133(7):1162-74
    • (2008) Cell , vol.133 , Issue.7 , pp. 1162-1174
    • Dejosez, M.1    Krumenacker, J.S.2    Zitur, L.J.3    Passeri, M.4    Chu, L.-F.5
  • 108
    • 0037310275 scopus 로고    scopus 로고
    • The THAP domain: A novel protein motif with similarity to the DNA-binding domain of P element transposase
    • RoussigneM, Kossida S, Lavigne A-C, Clouaire T, Ecochard V, et al. 2003. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem. Sci. 28(2):66-69
    • (2003) Trends Biochem. Sci. , vol.28 , Issue.2 , pp. 66-69
    • Roussigne, M.1    Kossida, S.2    Lavigne, A.-C.3    Clouaire, T.4    Ecochard, V.5
  • 109
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3 UTRs by comparison of several mammals
    • Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, et al. 2005. Systematic discovery of regulatory motifs in human promoters and 3 UTRs by comparison of several mammals. Nature 434(7031):338-45
    • (2005) Nature , vol.434 , Issue.7031 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.J.3    Golub, T.R.4    Mootha, V.5
  • 110
    • 79955781510 scopus 로고    scopus 로고
    • Identification of pluripotency genes in the fish medaka
    • Wang D, Manali D, Wang T, Bhat N, Hong N, et al. 2011. Identification of pluripotency genes in the fish medaka. Int. J. Biol. Sci. 7:440-51
    • (2011) Int. J. Biol. Sci. , vol.7 , pp. 440-451
    • Wang, D.1    Manali, D.2    Wang, T.3    Bhat, N.4    Hong, N.5
  • 111
    • 77957949804 scopus 로고    scopus 로고
    • A compendium of myelomaassociated chromosomal copy number abnormalities and their prognostic value
    • Walker BA, Leone PE, Chiecchio L, Dickens NJ, JennerMW, et al. 2010. A compendium of myelomaassociated chromosomal copy number abnormalities and their prognostic value. Blood 116(15):e56-65
    • (2010) Blood , vol.116 , Issue.15
    • Walker, B.A.1    Leone, P.E.2    Chiecchio, L.3    Dickens, N.J.4    Jenner, M.W.5
  • 112
    • 77955175049 scopus 로고    scopus 로고
    • Cross-species genomics matches driver mutations and cell compartments to model ependymoma
    • Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, et al. 2010. Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature 466(7306):632-36
    • (2010) Nature , vol.466 , Issue.7306 , pp. 632-636
    • Johnson, R.A.1    Wright, K.D.2    Poppleton, H.3    Mohankumar, K.M.4    Finkelstein, D.5
  • 113
    • 0037382574 scopus 로고    scopus 로고
    • Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
    • Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W. 2003. Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes Dev. 17(7):896-911
    • (2003) Genes Dev. , vol.17 , Issue.7 , pp. 896-911
    • Wysocka, J.1    Myers, M.P.2    Laherty, C.D.3    Eisenman, R.N.4    Herr, W.5
  • 114
    • 79551661274 scopus 로고    scopus 로고
    • O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1
    • Capotosti F, Guernier S, Lammers F, Waridel P, Cai Y, et al. 2011. O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell 144(3):376-88
    • (2011) Cell , vol.144 , Issue.3 , pp. 376-388
    • Capotosti, F.1    Guernier, S.2    Lammers, F.3    Waridel, P.4    Cai, Y.5
  • 115
    • 0034944121 scopus 로고    scopus 로고
    • Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines
    • Nichols J, Chambers I, Taga T, Smith A. 2001. Physiological rationale for responsiveness of mouse embryonic stem cells to gp130 cytokines. Development 128(12):2333-39
    • (2001) Development , vol.128 , Issue.12 , pp. 2333-2339
    • Nichols, J.1    Chambers, I.2    Taga, T.3    Smith, A.4
  • 116
    • 0034692605 scopus 로고    scopus 로고
    • Leukemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation
    • Zandstra PW, Le HV, Daley GQ, Griffith LG, Lauffenburger DA. 2000. Leukemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation. Biotechnol. Bioeng. 69(6):607-17
    • (2000) Biotechnol. Bioeng. , vol.69 , Issue.6 , pp. 607-617
    • Zandstra, P.W.1    Le, H.V.2    Daley, G.Q.3    Griffith, L.G.4    Lauffenburger, D.A.5
  • 117
    • 0032211619 scopus 로고    scopus 로고
    • Paracrine induction of stem cell renewal by LIF-deficient cells: A new ES cell regulatory pathway
    • Dani C, Chambers I, Johnstone S, Robertson M, Ebrahimi B, et al. 1998. Paracrine induction of stem cell renewal by LIF-deficient cells: a new ES cell regulatory pathway. Dev. Biol. 203(1):149-62
    • (1998) Dev. Biol. , vol.203 , Issue.1 , pp. 149-162
    • Dani, C.1    Chambers, I.2    Johnstone, S.3    Robertson, M.4    Ebrahimi, B.5
  • 118
    • 0032127977 scopus 로고    scopus 로고
    • Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
    • Niwa H, Burdon T, Chambers I, Smith A. 1998. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 12(13):2048-60
    • (1998) Genes Dev. , vol.12 , Issue.13 , pp. 2048-2060
    • Niwa, H.1    Burdon, T.2    Chambers, I.3    Smith, A.4
  • 119
    • 9144239955 scopus 로고    scopus 로고
    • Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling
    • Paling NRD, Wheadon H, Bone HK, WelhamMJ. 2004. Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling. J. Biol. Chem. 279(46):48063-70
    • (2004) J. Biol. Chem. , vol.279 , Issue.46 , pp. 48063-48070
    • Paling, N.R.D.1    Wheadon, H.2    Bone, H.K.3    Welham, M.J.4
  • 120
    • 67650032868 scopus 로고    scopus 로고
    • A parallel circuit of LIF signalling pathwaysmaintains pluripotency of mouse ES cells
    • Niwa H, Ogawa K, Shimosato D, Adachi K. 2009. A parallel circuit of LIF signalling pathwaysmaintains pluripotency of mouse ES cells. Nature 460(7251):118-22
    • (2009) Nature , vol.460 , Issue.7251 , pp. 118-122
    • Niwa, H.1    Ogawa, K.2    Shimosato, D.3    Adachi, K.4
  • 121
    • 69249098573 scopus 로고    scopus 로고
    • A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells
    • Eiselleova L, Matulka K, Kriz V, Kunova M, Schmidtova Z, et al. 2009. A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells. Stem Cells 27(8):1847-57
    • (2009) Stem Cells , vol.27 , Issue.8 , pp. 1847-1857
    • Eiselleova, L.1    Matulka, K.2    Kriz, V.3    Kunova, M.4    Schmidtova, Z.5
  • 122
    • 0034669082 scopus 로고    scopus 로고
    • Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture
    • Amit M, Carpenter MK, Inokuma MS, Chiu CP, Harris CP, et al. 2000. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev. Biol. 227(2):271-78
    • (2000) Dev. Biol. , vol.227 , Issue.2 , pp. 271-278
    • Amit, M.1    Carpenter, M.K.2    Inokuma, M.S.3    Chiu, C.P.4    Harris, C.P.5
  • 123
    • 48149098004 scopus 로고    scopus 로고
    • NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs
    • Xu R-H, Sampsell-Barron TL, Gu F, Root S, Peck RM, et al. 2008. NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell 3(2):196-206
    • (2008) Cell Stem Cell , vol.3 , Issue.2 , pp. 196-206
    • Xu, R.-H.1    Sampsell-Barron, T.L.2    Gu, F.3    Root, S.4    Peck, R.M.5
  • 124
    • 33646774001 scopus 로고    scopus 로고
    • GDF3 at the crossroads of TGF-beta signaling
    • Levine AJ, Brivanlou AH. 2006. GDF3 at the crossroads of TGF-beta signaling. Cell Cycle 5(10):1069-73
    • (2006) Cell Cycle , vol.5 , Issue.10 , pp. 1069-1073
    • Levine, A.J.1    Brivanlou, A.H.2
  • 125
    • 0025238437 scopus 로고
    • The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
    • Benezra R, Davis RL, LockshonD, TurnerDL, WeintraubH. 1990. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 61(1):49-59
    • (1990) Cell , vol.61 , Issue.1 , pp. 49-59
    • Benezra, R.1    Davis, R.L.2    Lockshon, D.3    Turner, D.L.4    Weintraub, H.5
  • 126
    • 0035025619 scopus 로고    scopus 로고
    • Direct neural fate specification from embryonic stem cells: A primitive mammalian neural stem cell stage acquired through a default mechanism
    • Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, Van der Kooy D. 2001. Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 30(1):65-78
    • (2001) Neuron , vol.30 , Issue.1 , pp. 65-78
    • Tropepe, V.1    Hitoshi, S.2    Sirard, C.3    Mak, T.W.4    Rossant, J.5    Van Der Kooy, D.6
  • 127
    • 0034932146 scopus 로고    scopus 로고
    • Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways
    • Ying Y, Qi X, Zhao GQ. 2001. Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways. Proc. Natl. Acad. Sci. USA 98(14):7858-62
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.14 , pp. 7858-7862
    • Ying, Y.1    Qi, X.2    Zhao, G.Q.3
  • 128
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying QL, Nichols J, Chambers I, Smith A. 2003. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115(3):281-92
    • (2003) Cell , vol.115 , Issue.3 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 129
    • 33745892388 scopus 로고    scopus 로고
    • Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
    • Suzuki A, Raya A, Kawakami Y, Morita M, Matsui T, et al. 2006. Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells. Proc. Natl. Acad. Sci. USA 103(27):10294-99
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.27 , pp. 10294-10299
    • Suzuki, A.1    Raya, A.2    Kawakami, Y.3    Morita, M.4    Matsui, T.5
  • 130
    • 1942533517 scopus 로고    scopus 로고
    • BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways
    • Qi X, Li T-G, Hao J, Hu J, Wang J, et al. 2004. BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc. Natl. Acad. Sci. USA 101(16):6027-32
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.16 , pp. 6027-6032
    • Qi, X.1    Li, T.-G.2    Hao, J.3    Hu, J.4    Wang, J.5
  • 131
    • 23644455006 scopus 로고    scopus 로고
    • Derivation of neural precursors from human embryonic stem cells in the presence of noggin
    • Itsykson P, Ilouz N, Turetsky T, Goldstein RS, Pera MF, et al. 2005. Derivation of neural precursors from human embryonic stem cells in the presence of noggin. Mol. Cell Neurosci. 30(1):24-36
    • (2005) Mol. Cell Neurosci. , vol.30 , Issue.1 , pp. 24-36
    • Itsykson, P.1    Ilouz, N.2    Turetsky, T.3    Goldstein, R.S.4    Pera, M.F.5
  • 132
    • 1842426937 scopus 로고    scopus 로고
    • Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin
    • Pera MF, Andrade J, Houssami S, Reubinoff B, Trounson A, et al. 2004. Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin. J. Cell Sci. 117(Pt. 7):1269-80
    • (2004) J. Cell Sci. , vol.117 , Issue.PART 7 , pp. 1269-1280
    • Pera, M.F.1    Andrade, J.2    Houssami, S.3    Reubinoff, B.4    Trounson, A.5
  • 133
    • 24644493315 scopus 로고    scopus 로고
    • Cripto-1: A multifunctional modulator during embryogenesis and oncogenesis
    • Strizzi L, Bianco C, Normanno N, Salomon D. 2005. Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis. Oncogene 24(37):5731-41
    • (2005) Oncogene , vol.24 , Issue.37 , pp. 5731-5741
    • Strizzi, L.1    Bianco, C.2    Normanno, N.3    Salomon, D.4
  • 134
    • 79951895413 scopus 로고    scopus 로고
    • Signaling pathways in embryonic stem cells
    • ed. VK Rajasekhar, MC Vemuri New York: Humana
    • Reynolds D, Vallier L, Chng Z, Pedersen R. 2009. Signaling pathways in embryonic stem cells. In Regulatory Networks in Stem Cells, ed. VK Rajasekhar, MC Vemuri, pp. 293-308. New York: Humana
    • (2009) Regulatory Networks in Stem Cells , pp. 293-308
    • Reynolds, D.1    Vallier, L.2    Chng, Z.3    Pedersen, R.4
  • 135
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. 2004. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 10(1):55-63
    • (2004) Nat. Med. , vol.10 , Issue.1 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 136
    • 0036295950 scopus 로고    scopus 로고
    • Characterisation of the phosphorylation of β-Catenin at the GSK-3 priming site Ser45
    • Hagen T, Vidal-Puig A. 2002. Characterisation of the phosphorylation of β-catenin at the GSK-3 priming site Ser45. Biochem. Biophys. Res. Commun. 294(2):324-28
    • (2002) Biochem. Biophys. Res. Commun. , vol.294 , Issue.2 , pp. 324-328
    • Hagen, T.1    Vidal-Puig, A.2
  • 137
    • 18244427021 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
    • Mao J, Wang J, Liu B, Pan W, Farr GH 3rd, et al. 2001. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol. Cell 7(4):801-9
    • (2001) Mol. Cell , vol.7 , Issue.4 , pp. 801-809
    • Mao, J.1    Wang, J.2    Liu, B.3    Pan, W.4    Farr Iii., G.H.5
  • 138
    • 0034232066 scopus 로고    scopus 로고
    • Curbing the nuclear activities of β-catenin. Control over Wnt target gene expression
    • Hecht A, Kemler R. 2000. Curbing the nuclear activities of β-catenin. Control over Wnt target gene expression. EMBO Rep. 1(1):24-28
    • (2000) EMBO Rep. , vol.1 , Issue.1 , pp. 24-28
    • Hecht, A.1    Kemler, R.2
  • 139
    • 78149337402 scopus 로고    scopus 로고
    • Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression
    • Wagner RT, Xu X, Yi F, Merrill BJ, Cooney AJ. 2010. Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression. Stem Cells 28(10):1794-804
    • (2010) Stem Cells , vol.28 , Issue.10 , pp. 1794-1804
    • Wagner, R.T.1    Xu, X.2    Yi, F.3    Merrill, B.J.4    Cooney, A.J.5
  • 140
    • 79551594937 scopus 로고    scopus 로고
    • β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
    • Kelly KF, Ng DY, Jayakumaran G, Wood GA, Koide H, Doble BW. 2011. β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell 8(2):214-27
    • (2011) Cell Stem Cell , vol.8 , Issue.2 , pp. 214-227
    • Kelly, K.F.1    Ng, D.Y.2    Jayakumaran, G.3    Wood, G.A.4    Koide, H.5    Doble, B.W.6
  • 141
    • 82355186665 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming
    • Miki T, Yasuda S-Y, Kahn M. 2011. Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming. Stem Cell Rev. 7(4):836-46
    • (2011) Stem Cell Rev. , vol.7 , Issue.4 , pp. 836-846
    • Miki, T.1    Yasuda, S.-Y.2    Kahn, M.3
  • 142
    • 77951920690 scopus 로고    scopus 로고
    • C-Myc regulates transcriptional pause release
    • Rahl PB, Lin CY, Seila AC, Flynn RA, McCuine S, et al. 2010. c-Myc regulates transcriptional pause release. Cell 141(3):432-45
    • (2010) Cell , vol.141 , Issue.3 , pp. 432-445
    • Rahl, P.B.1    Lin, C.Y.2    Seila, A.C.3    Flynn, R.A.4    McCuine, S.5
  • 143
  • 144
    • 34548434716 scopus 로고    scopus 로고
    • Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
    • Pan G, Tian S, Nie J, Yang C, Ruotti V, et al. 2007. Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1(3):299-312
    • (2007) Cell Stem Cell , vol.1 , Issue.3 , pp. 299-312
    • Pan, G.1    Tian, S.2    Nie, J.3    Yang, C.4    Ruotti, V.5
  • 145
    • 79951516056 scopus 로고    scopus 로고
    • A unique chromatin signature uncovers early developmental enhancers in humans
    • Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. 2011. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470(7333):279-83
    • (2011) Nature , vol.470 , Issue.7333 , pp. 279-283
    • Rada-Iglesias, A.1    Bajpai, R.2    Swigut, T.3    Brugmann, S.A.4    Flynn, R.A.5    Wysocka, J.6
  • 148
    • 33745865934 scopus 로고    scopus 로고
    • Chromatin in pluripotent embryonic stem cells and differentiation
    • Meshorer E, Misteli T. 2006. Chromatin in pluripotent embryonic stem cells and differentiation. Nat. Rev. Mol. Cell Biol. 7(7):540-46
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , Issue.7 , pp. 540-546
    • Meshorer, E.1    Misteli, T.2
  • 149
    • 79952660821 scopus 로고    scopus 로고
    • Control of the embryonic stem cell state
    • Young RA. 2011. Control of the embryonic stem cell state. Cell 144(6):940-54
    • (2011) Cell , vol.144 , Issue.6 , pp. 940-954
    • Young, R.A.1
  • 150
    • 35348982301 scopus 로고    scopus 로고
    • Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
    • Loh Y-H, ZhangW, Chen X, George J, Ng H-H. 2007. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev. 21(20):2545-57
    • (2007) Genes Dev. , vol.21 , Issue.20 , pp. 2545-2557
    • Loh, Y.-H.1    Zhang, W.2    Chen, X.3    George, J.4    Ng, H.-H.5
  • 151
    • 79955008193 scopus 로고    scopus 로고
    • KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription
    • Xie L, Pelz C, Wang W, Bashar A, Varlamova O, et al. 2011. KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription. EMBO J. 30(8):1473-84
    • (2011) EMBO J. , vol.30 , Issue.8 , pp. 1473-1484
    • Xie, L.1    Pelz, C.2    Wang, W.3    Bashar, A.4    Varlamova, O.5
  • 152
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron R, Reinberg D. 2011. The Polycomb complex PRC2 and its mark in life. Nature 469(7330):343-49
    • (2011) Nature , vol.469 , Issue.7330 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 153
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. 2006. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125(2):315-26
    • (2006) Cell , vol.125 , Issue.2 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5
  • 155
    • 77949414371 scopus 로고    scopus 로고
    • JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
    • Pasini D, Cloos PAC, Walfridsson J, Olsson L, Bukowski J-P, et al. 2010. JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells. Nature 464(7286):306-10
    • (2010) Nature , vol.464 , Issue.7286 , pp. 306-310
    • Pasini, D.1    Cloos, P.A.C.2    Walfridsson, J.3    Olsson, L.4    Bukowski, J.-P.5
  • 156
    • 72249119297 scopus 로고    scopus 로고
    • Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells
    • Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, et al. 2009. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell 139(7):1290-302
    • (2009) Cell , vol.139 , Issue.7 , pp. 1290-1302
    • Peng, J.C.1    Valouev, A.2    Swigut, T.3    Zhang, J.4    Zhao, Y.5
  • 157
    • 78649807567 scopus 로고    scopus 로고
    • Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA
    • Kaneko S, Li G, Son J, Xu C-F, Margueron R, et al. 2010. Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. Genes Dev. 24(23):2615-20
    • (2010) Genes Dev. , vol.24 , Issue.23 , pp. 2615-2620
    • Kaneko, S.1    Li, G.2    Son, J.3    Xu, C.-F.4    Margueron, R.5
  • 158
    • 79954414897 scopus 로고    scopus 로고
    • Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network
    • Ang Y-S, Tsai S-Y, Lee D-F, Monk J, Su J, et al. 2011. Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 145(2):183-97
    • (2011) Cell , vol.145 , Issue.2 , pp. 183-197
    • Ang, Y.-S.1    Tsai, S.-Y.2    Lee, D.-F.3    Monk, J.4    Su, J.5
  • 159
    • 79951711112 scopus 로고    scopus 로고
    • Role forDpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains
    • JiangH, Shukla A, Wang X, ChenW-y, Bernstein BE, Roeder RG. 2011. Role forDpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell 144(4):513-25
    • (2011) Cell , vol.144 , Issue.4 , pp. 513-525
    • Jiang, H.1    Shukla, A.2    Wang, X.3    Chen, W.-Y.4    Bernstein, B.E.5    Roeder, R.G.6
  • 160
    • 75749101495 scopus 로고    scopus 로고
    • Chromatin remodelling during development
    • Ho L, Crabtree GR. 2010. Chromatin remodelling during development. Nature 463(7280):474-84
    • (2010) Nature , vol.463 , Issue.7280 , pp. 474-484
    • Ho, L.1    Crabtree, G.R.2
  • 161
    • 0037089626 scopus 로고    scopus 로고
    • SETDB1: A novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
    • Schultz DC, Ayyanathan K, Negorev D, Maul GG, Rauscher FJ 3rd. 2002. SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins. Genes Dev. 16(8):919-32
    • (2002) Genes Dev. , vol.16 , Issue.8 , pp. 919-932
    • Schultz, D.C.1    Ayyanathan, K.2    Negorev, D.3    Maul, G.G.4    Rauscher Iii., F.J.5
  • 162
    • 77953727663 scopus 로고    scopus 로고
    • Chromatin-remodeling components of the BAF complex facilitate reprogramming
    • Singhal N, Graumann J, Wu G, Arauzo-Bravo MJ, Han DW, et al. 2010. Chromatin-remodeling components of the BAF complex facilitate reprogramming. Cell 141(6):943-55
    • (2010) Cell , vol.141 , Issue.6 , pp. 943-955
    • Singhal, N.1    Graumann, J.2    Wu, G.3    Arauzo-Bravo, M.J.4    Han, D.W.5
  • 164
    • 77957970498 scopus 로고    scopus 로고
    • Epigenetic modifications in pluripotent and differentiated cells
    • Meissner A. 2010. Epigenetic modifications in pluripotent and differentiated cells. Nat. Biotechnol. 28(10):1079-88
    • (2010) Nat. Biotechnol. , vol.28 , Issue.10 , pp. 1079-1088
    • Meissner, A.1
  • 165
    • 33745270104 scopus 로고    scopus 로고
    • Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
    • Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S, Sakaue M, et al. 2006. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11(7):805-14
    • (2006) Genes Cells , vol.11 , Issue.7 , pp. 805-814
    • Tsumura, A.1    Hayakawa, T.2    Kumaki, Y.3    Takebayashi, S.4    Sakaue, M.5
  • 166
    • 0030265336 scopus 로고    scopus 로고
    • Experimental manipulation of genomic methylation
    • Jackson-Grusby L, Jaenisch R. 1996. Experimental manipulation of genomic methylation. Semin. Cancer Biol. 7(5):261-68
    • (1996) Semin. Cancer Biol. , vol.7 , Issue.5 , pp. 261-268
    • Jackson-Grusby, L.1    Jaenisch, R.2
  • 167
    • 39149115929 scopus 로고    scopus 로고
    • Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
    • Stadtfeld M, Maherali N, Breault DT, Hochedlinger K. 2008. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2(3):230-40
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 230-240
    • Stadtfeld, M.1    Maherali, N.2    Breault, D.T.3    Hochedlinger, K.4
  • 168
    • 78751474118 scopus 로고    scopus 로고
    • Non-coding RNAs as regulators of embryogenesis
    • Pauli A, Rinn JL, Schier AF. 2011. Non-coding RNAs as regulators of embryogenesis. Nat. Rev. Genet. 12(2):136-49
    • (2011) Nat. Rev. Genet. , vol.12 , Issue.2 , pp. 136-149
    • Pauli, A.1    Rinn, J.L.2    Schier, A.F.3
  • 169
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R, et al. 2005. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19(4):489-501
    • (2005) Genes Dev. , vol.19 , Issue.4 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3    Ganesan, S.4    Drapkin, R.5
  • 171
    • 33847323881 scopus 로고    scopus 로고
    • DGC8is essential formicroRNA biogenesis and silencing of embryonic stem cell self-renewal
    • Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R. 2007.DGC8is essential formicroRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet. 39(3):380-85
    • (2007) Nat. Genet. , vol.39 , Issue.3 , pp. 380-385
    • Wang, Y.1    Medvid, R.2    Melton, C.3    Jaenisch, R.4    Blelloch, R.5
  • 172
    • 76249119007 scopus 로고    scopus 로고
    • Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
    • Melton C, Judson RL, Blelloch R. 2010. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463(7281):621-26
    • (2010) Nature , vol.463 , Issue.7281 , pp. 621-626
    • Melton, C.1    Judson, R.L.2    Blelloch, R.3
  • 173
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. 2009. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 137(4):647-58
    • (2009) Cell , vol.137 , Issue.4 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 174
    • 79954618976 scopus 로고    scopus 로고
    • Deregulation of MYCN LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
    • Helland A, Anglesio MS, George J, Cowin PA, Johnstone CN, et al. 2011. Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLoS ONE 6(4):e18064
    • (2011) PLoS ONE , vol.6 , Issue.4
    • Helland, A.1    Anglesio, M.S.2    George, J.3    Cowin, P.A.4    Johnstone, C.N.5
  • 175
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs promote induced pluripotency
    • Judson RL, Babiarz JE, Venere M, Blelloch R. 2009. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat. Biotechnol. 27(5):459-61
    • (2009) Nat. Biotechnol. , vol.27 , Issue.5 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 176
    • 79955780736 scopus 로고    scopus 로고
    • Multiple targets ofmiR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
    • SubramanyamD, Lamouille S, Judson RL, Liu JY, Bucay N, et al. 2011. Multiple targets ofmiR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat. Biotechnol. 29(5):443-48
    • (2011) Nat. Biotechnol. , vol.29 , Issue.5 , pp. 443-448
    • Subramanyam, D.1    Lamouille, S.2    Judson, R.L.3    Liu, J.Y.4    Bucay, N.5
  • 177
    • 79953881831 scopus 로고    scopus 로고
    • Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
    • Anokye-Danso F, Trivedi CM, Juhr D, GuptaM, Cui Z, et al. 2011. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8(4):376-88
    • (2011) Cell Stem Cell , vol.8 , Issue.4 , pp. 376-388
    • Anokye-Danso, F.1    Trivedi, C.M.2    Juhr, D.3    Guptam Cui, Z.4
  • 178
    • 78650196632 scopus 로고    scopus 로고
    • Regulation of somatic cell reprogramming through inducible mir-302 expression
    • Lin S-L, Chang DC, Lin C-H, Ying S-Y, Leu D, Wu DTS. 2011. Regulation of somatic cell reprogramming through inducible mir-302 expression. Nucleic Acids Res. 39(3):1054-65
    • (2011) Nucleic Acids Res. , vol.39 , Issue.3 , pp. 1054-1065
    • Lin, S.-L.1    Chang, D.C.2    Lin, C.-H.3    Ying, S.-Y.4    Leu, D.5    Wu, D.T.S.6
  • 179
    • 78549288558 scopus 로고    scopus 로고
    • MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of theCDK2and CDK4/6 cell cycle pathways
    • Lin S-L, Chang DC, Ying S-Y, Leu D, WuDTS. 2010. MicroRNA miR-302 inhibits the tumorigenecity of human pluripotent stem cells by coordinate suppression of theCDK2and CDK4/6 cell cycle pathways. Cancer Res. 70(22):9473-82
    • (2010) Cancer Res. , vol.70 , Issue.22 , pp. 9473-9482
    • Lin, S.-L.1    Chang, D.C.2    Ying, S.-Y.3    Leu, D.4    Wu, D.T.S.5
  • 180
    • 78649467088 scopus 로고    scopus 로고
    • Large intergenic non-coding RNA-RoRmodulates reprogramming of human induced pluripotent stem cells
    • Loewer S, Cabili MN, Guttman M, Loh Y-H, Thomas K, et al. 2010. Large intergenic non-coding RNA-RoRmodulates reprogramming of human induced pluripotent stem cells. Nat. Genet. 42(12):1113-17
    • (2010) Nat. Genet. , vol.42 , Issue.12 , pp. 1113-1117
    • Loewer, S.1    Cabili, M.N.2    Guttman, M.3    Loh, Y.-H.4    Thomas, K.5
  • 181
    • 75149163987 scopus 로고    scopus 로고
    • Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells
    • Sheik Mohamed J, Gaughwin PM, Lim B, Robson P, Lipovich L. 2010. Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA 16(2):324-37
    • (2010) RNA , vol.16 , Issue.2 , pp. 324-337
    • Sheik Mohamed, J.1    Gaughwin, P.M.2    Lim, B.3    Robson, P.4    Lipovich, L.5
  • 182
    • 0028131903 scopus 로고
    • Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer
    • Dailey L, Yuan H, Basilico C. 1994. Interaction between a novel F9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer. Mol. Cell. Biol. 14(12):7758-69
    • (1994) Mol. Cell. Biol. , vol.14 , Issue.12 , pp. 7758-7769
    • Dailey, L.1    Yuan, H.2    Basilico, C.3
  • 183
    • 79952638264 scopus 로고    scopus 로고
    • Cellular decision making and biological noise: From microbes to mammals
    • Balzsi G, Van Oudenaarden A, Collins JJ. 2011. Cellular decision making and biological noise: from microbes to mammals. Cell 144(6):910-25
    • (2011) Cell , vol.144 , Issue.6 , pp. 910-925
    • Balzsi, G.1    Van Oudenaarden, A.2    Collins, J.J.3
  • 184
    • 78149500053 scopus 로고    scopus 로고
    • Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages
    • Han DW, Tapia N, Joo JY, Greber B, Arauzo-Bravo MJ, et al. 2010. Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages. Cell 143(4):617-27
    • (2010) Cell , vol.143 , Issue.4 , pp. 617-627
    • Han, D.W.1    Tapia, N.2    Joo, J.Y.3    Greber, B.4    Arauzo-Bravo, M.J.5
  • 185
    • 70450193138 scopus 로고    scopus 로고
    • A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells
    • Hough SR, Laslett AL, Grimmond SB, Kolle G, Pera MF. 2009. A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells. PLoS ONE 4(11):e7708
    • (2009) PLoS ONE , vol.4 , Issue.11
    • Hough, S.R.1    Laslett, A.L.2    Grimmond, S.B.3    Kolle, G.4    Pera, M.F.5
  • 186
    • 33947382174 scopus 로고    scopus 로고
    • Transcriptional analysis of early lineage commitment in human embryonic stem cells
    • Laslett AL, Grimmond S, Gardiner B, Stamp L, Lin A, et al. 2007. Transcriptional analysis of early lineage commitment in human embryonic stem cells. BMC Dev. Biol. 7:12
    • (2007) BMC Dev. Biol. , vol.7 , pp. 12
    • Laslett, A.L.1    Grimmond, S.2    Gardiner, B.3    Stamp, L.4    Lin, A.5
  • 187
    • 70350627509 scopus 로고    scopus 로고
    • Epigenetic reversion of post-implantation epiblast to pluripotent
    • Bao S, Tang F, Li X, Hayashi K, Gillich A, et al. 2009. Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells. Nature 461(7268):1292-95
    • (2009) Nature , vol.461 , Issue.7268 , pp. 1292-1295
    • Bao, S.1    Tang, F.2    Li, X.3    Hayashi, K.4    Gillich, A.5
  • 188
    • 33947308285 scopus 로고    scopus 로고
    • How is pluripotency determined and maintained?
    • Niwa H. 2007. How is pluripotency determined and maintained? Development 134(4):635-46
    • (2007) Development , vol.134 , Issue.4 , pp. 635-646
    • Niwa, H.1
  • 189
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y. 1998. Caspases: enemies within. Science 281(5381):1312-16
    • (1998) Science , vol.281 , Issue.5381 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 190
    • 0033619265 scopus 로고    scopus 로고
    • Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1
    • De Maria R, Zeuner A, Eramo A, Domenichelli C, Bonci D, et al. 1999. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature 401(6752):489-93
    • (1999) Nature , vol.401 , Issue.6752 , pp. 489-493
    • De Maria, R.1    Zeuner, A.2    Eramo, A.3    Domenichelli, C.4    Bonci, D.5
  • 191
    • 44349188910 scopus 로고    scopus 로고
    • Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3
    • Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, et al. 2008. Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. Cell Stem Cell 2(6):584-94
    • (2008) Cell Stem Cell , vol.2 , Issue.6 , pp. 584-594
    • Janzen, V.1    Fleming, H.E.2    Riedt, T.3    Karlsson, G.4    Riese, M.J.5
  • 192
    • 44349111132 scopus 로고    scopus 로고
    • Caspase activity mediates the differentiation of embryonic stem cells
    • Fujita J, Crane AM, SouzaMK, DejosezM, KybaM, et al. 2008. Caspase activity mediates the differentiation of embryonic stem cells. Cell Stem Cell 2(6):595-601
    • (2008) Cell Stem Cell , vol.2 , Issue.6 , pp. 595-601
    • Fujita, J.1    Crane, A.M.2    Souza, M.K.3    Dejosez, M.4    Kyba, M.5
  • 193
    • 0029956641 scopus 로고    scopus 로고
    • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
    • Kuida K, Zheng TS, Na S, Kuan C, Yang D, et al. 1996. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384(6607):368-72
    • (1996) Nature , vol.384 , Issue.6607 , pp. 368-372
    • Kuida, K.1    Zheng, T.S.2    Na, S.3    Kuan, C.4    Yang, D.5
  • 194
    • 0033709907 scopus 로고    scopus 로고
    • Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
    • Zheng TS, Hunot S, Kuida K, Momoi T, Srinivasan A, et al. 2000. Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nat. Med. 6(11):1241-47
    • (2000) Nat. Med. , vol.6 , Issue.11 , pp. 1241-1247
    • Zheng, T.S.1    Hunot, S.2    Kuida, K.3    Momoi, T.4    Srinivasan, A.5
  • 195
    • 77957360239 scopus 로고    scopus 로고
    • Apoptotic caspases regulate induction of iPSCs from human fibroblasts
    • Li F, He Z, Shen J, Huang Q, Li W, et al. 2010. Apoptotic caspases regulate induction of iPSCs from human fibroblasts. Cell Stem Cell 7(4):508-20
    • (2010) Cell Stem Cell , vol.7 , Issue.4 , pp. 508-520
    • Li, F.1    He, Z.2    Shen, J.3    Huang, Q.4    Li, W.5
  • 196
    • 0035460556 scopus 로고    scopus 로고
    • Mouse germline restriction of Oct4 expression by germ cell nuclear factor
    • Fuhrmann G, Chung AC, Jackson KJ, Hummelke G, Baniahmad A, et al. 2001. Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev. Cell 1(3):377-87
    • (2001) Dev. Cell , vol.1 , Issue.3 , pp. 377-387
    • Fuhrmann, G.1    Chung, A.C.2    Jackson, K.J.3    Hummelke, G.4    Baniahmad, A.5
  • 197
    • 79960098405 scopus 로고    scopus 로고
    • Differential recruitment of methyl CpGbinding domain factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4
    • Gu P, Xu X, Le Menuet D, Chung AC-K, Cooney AJ. 2011. Differential recruitment of methyl CpGbinding domain factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4. Stem Cells 29(7):1041-51
    • (2011) Stem Cells , vol.29 , Issue.7 , pp. 1041-1051
    • Gu, P.1    Xu, X.2    Le Menuet, D.3    Ac-K, C.4    Cooney, A.J.5
  • 198
    • 33645132331 scopus 로고    scopus 로고
    • G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
    • Feldman N, Gerson A, Fang J, Li E, Zhang Y, et al. 2006. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat. Cell Biol. 8(2):188-94
    • (2006) Nat. Cell Biol. , vol.8 , Issue.2 , pp. 188-194
    • Feldman, N.1    Gerson, A.2    Fang, J.3    Li, E.4    Zhang, Y.5
  • 199
    • 0028821102 scopus 로고
    • A dynamic balance between ARP-1/COUPTFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells
    • Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y. 1995. A dynamic balance between ARP-1/COUPTFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol. Cell. Biol. 15(2):1034-48
    • (1995) Mol. Cell. Biol. , vol.15 , Issue.2 , pp. 1034-1048
    • Ben-Shushan, E.1    Sharir, H.2    Pikarsky, E.3    Bergman, Y.4
  • 200
    • 79959950773 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    • Wray J, Kalkan T, Gomez-Lopez S, Eckardt D, Cook A, et al. 2011. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat. Cell Biol. 13(7):838-45
    • (2011) Nat. Cell Biol. , vol.13 , Issue.7 , pp. 838-845
    • Wray, J.1    Kalkan, T.2    Gomez-Lopez, S.3    Eckardt, D.4    Cook, A.5


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