Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

Development

Volumn 136, Issue 8, 2009, Pages 1339-1349

  Vallier, Ludovic ^a   Mendjan, Sasha ^a   Brown, Stephanie ^a   Ching, Zhenzhi ^a   Teo, Adrian ^a   Smithers, Lucy E ^b,d   Trotter, Matthew W B ^a,b   Cho, Candy H H ^a   Martinez, Amelie ^c   Rugg Gunn, Peter ^a,e   Brons, Gabrielle ^a   Pedersen, Roger A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c INSERM   (France)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Activin; Endoderm; Extraembryonic; hESCs; Human; Mesendoderm; Mouse; Nanog; Neuroectoderm; Nodal; Smad2 3

Indexed keywords

ACTIVIN; BONE MORPHOGENETIC PROTEIN 4; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN NODAL; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GBX2; TRANSCRIPTION FACTOR HOXA1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX1; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; BONE MORPHOGENETIC PROTEIN; FIBROBLAST GROWTH FACTOR 2; HOMEODOMAIN PROTEIN; NANOG PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL GROWTH; CELL LINEAGE; CELL POPULATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; EMBRYO; ENDODERM; GASTRULATION; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOSS; GENE MUTATION; HUMAN; HUMAN CELL; MESODERM; NERVE CELL DIFFERENTIATION; NEUROECTODERM; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; GENE EXPRESSION PROFILING; GENETICS; GERM LAYER; METABOLISM; MOUSE; NERVE CELL; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION;

ACTIVINS; ANIMALS; BIOLOGICAL MARKERS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GERM LAYERS; HOMEODOMAIN PROTEINS; HUMANS; MICE; NEURONS; NODAL PROTEIN; PLURIPOTENT STEM CELLS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN;

EID: 67650096520     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.033951     Document Type: Article

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