Molecular coupling of Xist regulation and pluripotency

Science

Volumn 321, Issue 5896, 2008, Pages 1693-1695

  Navarro, Pablo ^a   Chambers, Ian ^b   Karwacki Neisius, Violetta ^b   Chureau, Corinne ^a   Morey, Céline ^a   Rougeulle, Claire ^a   Avner, Philip ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; RNA; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

CELL ORGANELLE; CHROMOSOME; EMBRYO; EMBRYONIC DEVELOPMENT; RNA; RODENT;

ANIMAL CELL; ARTICLE; BLASTOCYST; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; FEMALE; GENE; GENE REPRESSION; INNER CELL MASS; INTRON; MALE; MOUSE; NANOG GENE; NONHUMAN; OCT3 GENE; OCT4 GENE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SOX2 GENE; UPREGULATION; X CHROMOSOME; X CHROMOSOME INACTIVATION; XIST GENE;

ANIMALS; BLASTOCYST INNER CELL MASS; CELL DIFFERENTIATION; CELL LINE; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; FEMALE; HMGB PROTEINS; HOMEODOMAIN PROTEINS; INTRONS; MALE; MICE; OCTAMER TRANSCRIPTION FACTOR-3; PLURIPOTENT STEM CELLS; RNA, UNTRANSLATED; TRANSCRIPTION FACTORS; UP-REGULATION; X CHROMOSOME; X CHROMOSOME INACTIVATION;

EID: 52249096815     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1160952     Document Type: Article

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26. We thank D. Colby for technical assistance, members of our laboratories for stimulating discussion, and A. Smith for the gift of the ZHBTc4 ES cell line. P.N., C.C., C.R., and P.A. were supported by recurrent funding from the CNRS and the Institut Pasteur, contracts 05-JCJC-0166-01 and 07-BLAN-0047-01 from the Agence Nationale de Recherche, and funding from the EU Epigenome Network of Excellence. Research in I.C.'s laboratory was supported by the Wellcome Trust, the Juvenile Diabetes Research Foundation, and the Biotechnological and Biological Sciences and Medical Research Councils of the UK.