-
3
-
-
77649179672
-
Eicosanoids and cancer
-
D. Wang, and R.N. Dubois Eicosanoids and cancer Nat Rev Cancer 10 2010 181 193
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 181-193
-
-
Wang, D.1
Dubois, R.N.2
-
4
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
-
C.E. Eberhart, R.J. Coffey, A. Radhika, F.M. Giardiello, S. Ferrenbach, and R.N. Dubois Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas Gastroenterology 107 1994 1183 1188
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
Giardiello, F.M.4
Ferrenbach, S.5
Dubois, R.N.6
-
5
-
-
0141854494
-
Expression of cyclooxygenase-2 in human gastric carcinoma
-
A. Ristimäki, N. Honkanen, H. Jänkälä, P. Sipponen, and M. Härkönen Expression of cyclooxygenase-2 in human gastric carcinoma Cancer Res 57 1997 1276 1280
-
(1997)
Cancer Res
, vol.57
, pp. 1276-1280
-
-
Ristimäki, A.1
Honkanen, N.2
Jänkälä, H.3
Sipponen, P.4
Härkönen, M.5
-
6
-
-
0032533858
-
Expression of cyclooxygenase-2 in human lung carcinoma
-
H. Wolff, K. Saukkonen, S. Anttila, A. Karjalainen, H. Vainio, and A. Ristimäki Expression of cyclooxygenase-2 in human lung carcinoma Cancer Res 58 1998 4997 5001
-
(1998)
Cancer Res
, vol.58
, pp. 4997-5001
-
-
Wolff, H.1
Saukkonen, K.2
Anttila, S.3
Karjalainen, A.4
Vainio, H.5
Ristimäki, A.6
-
7
-
-
0029851291
-
Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines
-
X.H. Liu, and D.P. Rose Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines Cancer Res 56 1996 5125 5127
-
(1996)
Cancer Res
, vol.56
, pp. 5125-5127
-
-
Liu, X.H.1
Rose, D.P.2
-
8
-
-
71349088198
-
Cyclooxygenase in normal human tissues: Is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?
-
N. Zidar, K. Odar, D. Glavac, M. Jerse, T. Zupanc, and D. Stajer Cyclooxygenase in normal human tissues: is COX-1 really a constitutive isoform, and COX-2 an inducible isoform? J Cell Mol Med 13 2009 3753 3763
-
(2009)
J Cell Mol Med
, vol.13
, pp. 3753-3763
-
-
Zidar, N.1
Odar, K.2
Glavac, D.3
Jerse, M.4
Zupanc, T.5
Stajer, D.6
-
9
-
-
0034008165
-
High cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) contents in mouse lung tumors
-
A.K. Bauer, L.D. Dwyer-Nield, and A.M. Malkinson High cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) contents in mouse lung tumors Carcinogenesis 21 2000 543 550
-
(2000)
Carcinogenesis
, vol.21
, pp. 543-550
-
-
Bauer, A.K.1
Dwyer-Nield, L.D.2
Malkinson, A.M.3
-
10
-
-
24144447706
-
Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells
-
J.T. Nurmi, P.A. Puolakkainen, and N.E. Rautonen Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells Prostaglandins Leukotrienes Essent Fatty Acids 73 2005 343 350
-
(2005)
Prostaglandins Leukotrienes Essent Fatty Acids
, vol.73
, pp. 343-350
-
-
Nurmi, J.T.1
Puolakkainen, P.A.2
Rautonen, N.E.3
-
11
-
-
33747028253
-
Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer
-
S. Chell, A. Kaidi, A.C. Williams, and C. Paraskeva Mediators of PGE2 synthesis and signalling downstream of COX-2 represent potential targets for the prevention/treatment of colorectal cancer Biochim Biophys Acta 1766 2006 104 119
-
(2006)
Biochim Biophys Acta
, vol.1766
, pp. 104-119
-
-
Chell, S.1
Kaidi, A.2
Williams, A.C.3
Paraskeva, C.4
-
13
-
-
78651347917
-
Cigarette smoking, cyclooxygenase-2 pathway and cancer
-
R.Y. Huang, and G.G. Chen Cigarette smoking, cyclooxygenase-2 pathway and cancer Biochim Biophys Acta 1815 2011 158 169
-
(2011)
Biochim Biophys Acta
, vol.1815
, pp. 158-169
-
-
Huang, R.Y.1
Chen, G.G.2
-
14
-
-
0031843401
-
COX-2 expression is induced by UVB exposure in human skin: Implications for the development of skin cancer
-
S.Y. Buckman, A. Gresham, P. Hale, G. Hruza, J. Anast, and J. Masferrer COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer Carcinogenesis 19 1998 723 729
-
(1998)
Carcinogenesis
, vol.19
, pp. 723-729
-
-
Buckman, S.Y.1
Gresham, A.2
Hale, P.3
Hruza, G.4
Anast, J.5
Masferrer, J.6
-
15
-
-
79958204979
-
Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-{alpha}
-
K.H. Weylandt, L.F. Krause, B. Gomolka, C.-Y. Chiu, S. Bilal, and A. Nadolny Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-{alpha} Carcinogenesis 2011
-
(2011)
Carcinogenesis
-
-
Weylandt, K.H.1
Krause, L.F.2
Gomolka, B.3
Chiu, C.-Y.4
Bilal, S.5
Nadolny, A.6
-
16
-
-
0033531266
-
Evolutionary conservation and somatic mutation hotspot maps of p53: Correlation with p53 protein structural and functional features
-
D.R. Walker, J.P. Bond, R.E. Tarone, C.C. Harris, W. Makalowski, and M.S. Boguski Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features Oncogene 18 1999 211 218
-
(1999)
Oncogene
, vol.18
, pp. 211-218
-
-
Walker, D.R.1
Bond, J.P.2
Tarone, R.E.3
Harris, C.C.4
Makalowski, W.5
Boguski, M.S.6
-
17
-
-
42549119900
-
Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth
-
H. Funahashi, M. Satake, S. Hasan, H. Sawai, R.A. Newman, and H.A. Reber Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth Pancreas 36 2008 353 362
-
(2008)
Pancreas
, vol.36
, pp. 353-362
-
-
Funahashi, H.1
Satake, M.2
Hasan, S.3
Sawai, H.4
Newman, R.A.5
Reber, H.A.6
-
18
-
-
41349117825
-
Arachidonic acid modulates the crosstalk between prostate carcinoma and bone stromal cells
-
A. Angelucci, S. Garofalo, S. Speca, A. Bovadilla, G.L. Gravina, and P. Muzi Arachidonic acid modulates the crosstalk between prostate carcinoma and bone stromal cells Endocr Relat Cancer 15 2008 91 100
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 91-100
-
-
Angelucci, A.1
Garofalo, S.2
Speca, S.3
Bovadilla, A.4
Gravina, G.L.5
Muzi, P.6
-
19
-
-
0035036867
-
Fatty acid regulates gene expression and growth of human prostate cancer PC-3 cells
-
M. Hughes-Fulford, Y. Chen, and R.R. Tjandrawinata Fatty acid regulates gene expression and growth of human prostate cancer PC-3 cells Carcinogenesis 22 2001 701 707
-
(2001)
Carcinogenesis
, vol.22
, pp. 701-707
-
-
Hughes-Fulford, M.1
Chen, Y.2
Tjandrawinata, R.R.3
-
20
-
-
0032860560
-
Omega-3 fatty acids as cancer chemopreventive agents
-
D.P. Rose, and J.M. Connolly Omega-3 fatty acids as cancer chemopreventive agents Pharmacol Ther 83 1999 217 244
-
(1999)
Pharmacol Ther
, vol.83
, pp. 217-244
-
-
Rose, D.P.1
Connolly, J.M.2
-
21
-
-
26444564805
-
Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA
-
Y.-W.E. Chang, K. Putzer, L. Ren, B. Kaboord, T.W. Chance, and M.W. Qoronfleh Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA J Cell Biochem 96 2005 314 329
-
(2005)
J Cell Biochem
, vol.96
, pp. 314-329
-
-
Chang, Y.-W.E.1
Putzer, K.2
Ren, L.3
Kaboord, B.4
Chance, T.W.5
Qoronfleh, M.W.6
-
22
-
-
12644261426
-
Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells
-
R.J. Coffey, C.J. Hawkey, L. Damstrup, R. Graves-Deal, V.C. Daniel, and P.J. Dempsey Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells Proc Natl Acad Sci U S A 94 1997 657 662
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 657-662
-
-
Coffey, R.J.1
Hawkey, C.J.2
Damstrup, L.3
Graves-Deal, R.4
Daniel, V.C.5
Dempsey, P.J.6
-
23
-
-
19944432973
-
Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: Evidence for the role of epidermal growth factor receptor and its ligands
-
D. Moraitis, B. Du, M.S. De Lorenzo, J.O. Boyle, B.B. Weksler, and E.G. Cohen Levels of cyclooxygenase-2 are increased in the oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands Cancer Res 65 2005 664 670
-
(2005)
Cancer Res
, vol.65
, pp. 664-670
-
-
Moraitis, D.1
Du, B.2
De Lorenzo, M.S.3
Boyle, J.O.4
Weksler, B.B.5
Cohen, E.G.6
-
24
-
-
68349102201
-
Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis
-
J.R. Reed, R.P. Leon, M.K. Hall, and K.L. Schwertfeger Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis Breast Cancer Res 11 2009 R21
-
(2009)
Breast Cancer Res
, vol.11
, pp. 21
-
-
Reed, J.R.1
Leon, R.P.2
Hall, M.K.3
Schwertfeger, K.L.4
-
25
-
-
65649086413
-
Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma
-
K.-Y. Chang, M.-R. Shen, M.-Y. Lee, W.-L. Wang, W.-C. Su, and W.-C. Chang Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma J Biol Chem 284 2009 9908 9916
-
(2009)
J Biol Chem
, vol.284
, pp. 9908-9916
-
-
Chang, K.-Y.1
Shen, M.-R.2
Lee, M.-Y.3
Wang, W.-L.4
Su, W.-C.5
Chang, W.-C.6
-
26
-
-
0033290356
-
Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells
-
D. Saha, P.K. Datta, H. Sheng, J.D. Morrow, M. Wada, and H.L. Moses Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells Neoplasia 1 1999 508 517
-
(1999)
Neoplasia
, vol.1
, pp. 508-517
-
-
Saha, D.1
Datta, P.K.2
Sheng, H.3
Morrow, J.D.4
Wada, M.5
Moses, H.L.6
-
27
-
-
0038079768
-
Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways
-
W. Liu, N. Reinmuth, O. Stoeltzing, A.A. Parikh, C. Tellez, and S. Williams Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways Cancer Res 63 2003 3632 3636
-
(2003)
Cancer Res
, vol.63
, pp. 3632-3636
-
-
Liu, W.1
Reinmuth, N.2
Stoeltzing, O.3
Parikh, A.A.4
Tellez, C.5
Williams, S.6
-
28
-
-
0034523095
-
Helicobacter pylori, gastrin and cyclooxygenases in gastric cancer
-
P.C. Konturek, A. Hartwich, M. Zuchowicz, H. Labza, P. Pierzchalski, and E. Karczewska Helicobacter pylori, gastrin and cyclooxygenases in gastric cancer J Physiol Pharmacol 51 2000 737 749
-
(2000)
J Physiol Pharmacol
, vol.51
, pp. 737-749
-
-
Konturek, P.C.1
Hartwich, A.2
Zuchowicz, M.3
Labza, H.4
Pierzchalski, P.5
Karczewska, E.6
-
29
-
-
9444252934
-
Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation
-
Y.J. Chang, M.S. Wu, J.T. Lin, B.S. Sheu, T. Muta, and H. Inoue Induction of cyclooxygenase-2 overexpression in human gastric epithelial cells by Helicobacter pylori involves TLR2/TLR9 and c-Src-dependent nuclear factor-kappaB activation Mol Pharmacol 66 2004 1465 1477
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1465-1477
-
-
Chang, Y.J.1
Wu, M.S.2
Lin, J.T.3
Sheu, B.S.4
Muta, T.5
Inoue, H.6
-
30
-
-
33646029063
-
Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells
-
M.M.M. Abdel-Latif, H. Windle, A. Terres, D.N. Eidhin, D. Kelleher, and J.V. Reynolds Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells J Gastrointest Surg 10 2006 551 562
-
(2006)
J Gastrointest Surg
, vol.10
, pp. 551-562
-
-
Abdel-Latif, M.M.M.1
Windle, H.2
Terres, A.3
Eidhin, D.N.4
Kelleher, D.5
Reynolds, J.V.6
-
31
-
-
11444254589
-
Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancer
-
A. Singh, H. Sharma, S. Salhan, S.D. Gupta, N. Bhatla, and S.K. Jain Evaluation of expression of apoptosis-related proteins and their correlation with HPV, telomerase activity, and apoptotic index in cervical cancer Pathobiology 71 2004 314 322
-
(2004)
Pathobiology
, vol.71
, pp. 314-322
-
-
Singh, A.1
Sharma, H.2
Salhan, S.3
Gupta, S.D.4
Bhatla, N.5
Jain, S.K.6
-
32
-
-
4744351642
-
Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: Implication of HBx in upregulation of COX-2
-
A.S.-L. Cheng, H.L.-Y. Chan, W.K. Leung, K.F. To, M.Y.-Y. Go, and J.Y.-H. Chan Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2 Mod Pathol 17 2004 1169 1179
-
(2004)
Mod Pathol
, vol.17
, pp. 1169-1179
-
-
Cheng, A.S.-L.1
Chan, H.L.-Y.2
Leung, W.K.3
To, K.F.4
Go, M.Y.-Y.5
Chan, J.Y.-H.6
-
33
-
-
31144443233
-
Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1
-
R. Kaul, S.C. Verma, M. Murakami, K. Lan, T. Choudhuri, and E.S. Robertson Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1 J Virol 80 2006 1321 1331
-
(2006)
J Virol
, vol.80
, pp. 1321-1331
-
-
Kaul, R.1
Verma, S.C.2
Murakami, M.3
Lan, K.4
Choudhuri, T.5
Robertson, E.S.6
-
34
-
-
0036955336
-
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression
-
E. Lara-Pezzi, M.V. Gómez-Gaviro, B.G. Gálvez, E. Mira, M.A. Iñiguez, and M. Fresno The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression J Clin Invest 110 2002 1831 1838
-
(2002)
J Clin Invest
, vol.110
, pp. 1831-1838
-
-
Lara-Pezzi, E.1
Gómez-Gaviro, M.V.2
Gálvez, B.G.3
Mira, E.4
Iñiguez, M.A.5
Fresno, M.6
-
35
-
-
22544447811
-
Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: Role of prostaglandin E2 in RNA replication
-
G. Waris, and A. Siddiqui Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication J Virol 79 2005 9725 9734
-
(2005)
J Virol
, vol.79
, pp. 9725-9734
-
-
Waris, G.1
Siddiqui, A.2
-
36
-
-
0035811070
-
Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells
-
S. Murono, H. Inoue, T. Tanabe, I. Joab, T. Yoshizaki, and M. Furukawa Induction of cyclooxygenase-2 by Epstein-Barr virus latent membrane protein 1 is involved in vascular endothelial growth factor production in nasopharyngeal carcinoma cells Proc Natl Acad Sci U S A 98 2001 6905 6910
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 6905-6910
-
-
Murono, S.1
Inoue, H.2
Tanabe, T.3
Joab, I.4
Yoshizaki, T.5
Furukawa, M.6
-
37
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
38
-
-
0031789369
-
Resistance to apoptosis and cyclooxygenase-2 expression in a human adenocarcinoma cell line HT29 CL.19A
-
S. Battu, M. Rigaud, and J.L. Beneytout Resistance to apoptosis and cyclooxygenase-2 expression in a human adenocarcinoma cell line HT29 CL.19A Anticancer Res 18 1998 3579 3583
-
(1998)
Anticancer Res
, vol.18
, pp. 3579-3583
-
-
Battu, S.1
Rigaud, M.2
Beneytout, J.L.3
-
39
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
M. Tsujii, and R.N. DuBois Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 Cell 83 1995 493 501
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
Dubois, R.N.2
-
40
-
-
0036735391
-
Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells
-
X. Tang, Y.J. Sun, E. Half, M.T. Kuo, and F. Sinicrope Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells Cancer Res 62 2002 4903 4908
-
(2002)
Cancer Res
, vol.62
, pp. 4903-4908
-
-
Tang, X.1
Sun, Y.J.2
Half, E.3
Kuo, M.T.4
Sinicrope, F.5
-
41
-
-
0345549483
-
Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition
-
G. Totzke, K. Schulze-Osthoff, and R.U. Jänicke Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition Oncogene 22 2003 8021 8030
-
(2003)
Oncogene
, vol.22
, pp. 8021-8030
-
-
Totzke, G.1
Schulze-Osthoff, K.2
Jänicke, R.U.3
-
42
-
-
33748176994
-
COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis
-
Y. Yamanaka, K. Shiraki, T. Inoue, K. Miyashita, H. Fuke, and Y. Yamaguchi COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis Int J Mol Med 18 2006 41 47
-
(2006)
Int J Mol Med
, vol.18
, pp. 41-47
-
-
Yamanaka, Y.1
Shiraki, K.2
Inoue, T.3
Miyashita, K.4
Fuke, H.5
Yamaguchi, Y.6
-
43
-
-
29244467982
-
Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae
-
S. Martin, D.C. Phillips, K. Szekely-Szucs, L. Elghazi, F. Desmots, and J.A. Houghton Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae Cancer Res 65 2005 11447 11458
-
(2005)
Cancer Res
, vol.65
, pp. 11447-11458
-
-
Martin, S.1
Phillips, D.C.2
Szekely-Szucs, K.3
Elghazi, L.4
Desmots, F.5
Houghton, J.A.6
-
44
-
-
2442696835
-
Reduced T-cell and dendritic cell function is related to cyclooxygenase-2 overexpression and prostaglandin E2 secretion in patients with breast cancer
-
B.A. Pockaj, G.D. Basu, L.B. Pathangey, R.J. Gray, J.L. Hernandez, and S.J. Gendler Reduced T-cell and dendritic cell function is related to cyclooxygenase-2 overexpression and prostaglandin E2 secretion in patients with breast cancer Ann Surg Oncol 11 2004 328 339
-
(2004)
Ann Surg Oncol
, vol.11
, pp. 328-339
-
-
Pockaj, B.A.1
Basu, G.D.2
Pathangey, L.B.3
Gray, R.J.4
Hernandez, J.L.5
Gendler, S.J.6
-
45
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
R. Pai, B. Soreghan, I.L. Szabo, M. Pavelka, D. Baatar, and A.S. Tarnawski Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy Nat Med 8 2002 289 293
-
(2002)
Nat Med
, vol.8
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
Pavelka, M.4
Baatar, D.5
Tarnawski, A.S.6
-
46
-
-
0033583583
-
Growth stimulation and induction of epidermal growth factor receptor by overexpression of cyclooxygenases 1 and 2 in human colon carcinoma cells
-
T. Kinoshita, Y. Takahashi, T. Sakashita, H. Inoue, T. Tanabe, and T. Yoshimoto Growth stimulation and induction of epidermal growth factor receptor by overexpression of cyclooxygenases 1 and 2 in human colon carcinoma cells Biochim Biophys Acta 1438 1999 120 130
-
(1999)
Biochim Biophys Acta
, vol.1438
, pp. 120-130
-
-
Kinoshita, T.1
Takahashi, Y.2
Sakashita, T.3
Inoue, H.4
Tanabe, T.5
Yoshimoto, T.6
-
47
-
-
0030444771
-
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene
-
Y. Zhao, V.R. Agarwal, C.R. Mendelson, and E.R. Simpson Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene Endocrinology 137 1996 5739 5742
-
(1996)
Endocrinology
, vol.137
, pp. 5739-5742
-
-
Zhao, Y.1
Agarwal, V.R.2
Mendelson, C.R.3
Simpson, E.R.4
-
48
-
-
28544444039
-
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
-
M.D. Castellone, H. Teramoto, B.O. Williams, K.M. Druey, and J.S. Gutkind Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis Science 310 2005 1504 1510
-
(2005)
Science
, vol.310
, pp. 1504-1510
-
-
Castellone, M.D.1
Teramoto, H.2
Williams, B.O.3
Druey, K.M.4
Gutkind, J.S.5
-
49
-
-
0035097541
-
Cyclooxygenase-2 pathway correlates with VEGF expression in head and neck cancer. implications for tumor angiogenesis and metastasis
-
O. Gallo, A. Franchi, L. Magnelli, I. Sardi, A. Vannacci, and V. Boddi Cyclooxygenase-2 pathway correlates with VEGF expression in head and neck cancer. implications for tumor angiogenesis and metastasis Neoplasia 3 2001 53 61
-
(2001)
Neoplasia
, vol.3
, pp. 53-61
-
-
Gallo, O.1
Franchi, A.2
Magnelli, L.3
Sardi, I.4
Vannacci, A.5
Boddi, V.6
-
50
-
-
0034161878
-
Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
-
J.L. Masferrer, K.M. Leahy, A.T. Koki, B.S. Zweifel, S.L. Settle, and B.M. Woerner Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors Cancer Res 60 2000 1306 1311
-
(2000)
Cancer Res
, vol.60
, pp. 1306-1311
-
-
Masferrer, J.L.1
Leahy, K.M.2
Koki, A.T.3
Zweifel, B.S.4
Settle, S.L.5
Woerner, B.M.6
-
51
-
-
3042674629
-
Cyclooxygenase-2 upregulates vascular endothelial growth factor expression and angiogenesis in human gastric carcinoma
-
W.K. Leung, K.F. To, M.Y.Y. Go, K.-K. Chan, F.K.L. Chan, and E.K.W. Ng Cyclooxygenase-2 upregulates vascular endothelial growth factor expression and angiogenesis in human gastric carcinoma Int J Oncol 23 2003 1317 1322
-
(2003)
Int J Oncol
, vol.23
, pp. 1317-1322
-
-
Leung, W.K.1
To, K.F.2
Go, M.Y.Y.3
Chan, K.-K.4
Chan, F.K.L.5
Ng, E.K.W.6
-
52
-
-
30744478221
-
Expression of cyclooxygenase-2 and matrix metalloproteinase-9 in gastric carcinoma and its correlation with angiogenesis
-
W.H. Sun, Y.L. Sun, R.N. Fang, Y. Shao, H.C. Xu, and Q.P. Xue Expression of cyclooxygenase-2 and matrix metalloproteinase-9 in gastric carcinoma and its correlation with angiogenesis Jpn J Clin Oncol 35 2005 707 713
-
(2005)
Jpn J Clin Oncol
, vol.35
, pp. 707-713
-
-
Sun, W.H.1
Sun, Y.L.2
Fang, R.N.3
Shao, Y.4
Xu, H.C.5
Xue, Q.P.6
-
53
-
-
0030952695
-
Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
-
M. Tsujii, S. Kawano, and R.N. DuBois Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential Proc Natl Acad Sci U S A 94 1997 3336 3340
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 3336-3340
-
-
Tsujii, M.1
Kawano, S.2
Dubois, R.N.3
-
54
-
-
15244360281
-
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer
-
A. Sivula, A. Talvensaari-Mattila, J. Lundin, H. Joensuu, C. Haglund, and A. Ristimäki Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer Breast Cancer Res Treat 89 2005 215 220
-
(2005)
Breast Cancer Res Treat
, vol.89
, pp. 215-220
-
-
Sivula, A.1
Talvensaari-Mattila, A.2
Lundin, J.3
Joensuu, H.4
Haglund, C.5
Ristimäki, A.6
-
55
-
-
33745686438
-
Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer
-
J.H. Byun, M.A. Lee, S.Y. Roh, B.Y. Shim, S.H. Hong, and Y.H. Ko Association between cyclooxygenase-2 and matrix metalloproteinase-2 expression in non-small cell lung cancer Jpn J Clin Oncol 36 2006 263 268
-
(2006)
Jpn J Clin Oncol
, vol.36
, pp. 263-268
-
-
Byun, J.H.1
Lee, M.A.2
Roh, S.Y.3
Shim, B.Y.4
Hong, S.H.5
Ko, Y.H.6
-
56
-
-
33748358343
-
Inhibition of cyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression
-
T.L. Larkins, M. Nowell, S. Singh, and G.L. Sanford Inhibition of cyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression BMC Cancer 6 2006 181
-
(2006)
BMC Cancer
, vol.6
, pp. 181
-
-
Larkins, T.L.1
Nowell, M.2
Singh, S.3
Sanford, G.L.4
-
57
-
-
19944392908
-
Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44
-
Y. Kinugasa, M. Hatori, H. Ito, Y. Kurihara, D. Ito, and M. Nagumo Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44 Clin Exp Metastasis 21 2004 737 745
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 737-745
-
-
Kinugasa, Y.1
Hatori, M.2
Ito, H.3
Kurihara, Y.4
Ito, D.5
Nagumo, M.6
-
58
-
-
0030606299
-
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
M. Oshima, J.E. Dinchuk, S.L. Kargman, H. Oshima, B. Hancock, and E. Kwong Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) Cell 87 1996 803 809
-
(1996)
Cell
, vol.87
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
Oshima, H.4
Hancock, B.5
Kwong, E.6
-
59
-
-
0034282465
-
Genetic disruption of PTGS-1, as well as PTGS-2, reduces intestinal tumorigenesis in Min mice
-
P.C. Chulada, M.B. Thompson, J.F. Mahler, C.M. Doyle, B.W. Gaul, and C. Lee Genetic disruption of PTGS-1, as well as PTGS-2, reduces intestinal tumorigenesis in Min mice Cancer Res 60 2000 4705 4708
-
(2000)
Cancer Res
, vol.60
, pp. 4705-4708
-
-
Chulada, P.C.1
Thompson, M.B.2
Mahler, J.F.3
Doyle, C.M.4
Gaul, B.W.5
Lee, C.6
-
60
-
-
0344237231
-
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
-
T. Tanaka, H. Kohno, R. Suzuki, Y. Yamada, S. Sugie, and H. Mori A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate Cancer Sci 94 2003 965 973
-
(2003)
Cancer Sci
, vol.94
, pp. 965-973
-
-
Tanaka, T.1
Kohno, H.2
Suzuki, R.3
Yamada, Y.4
Sugie, S.5
Mori, H.6
-
61
-
-
64049109107
-
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
-
R.E. Harris Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung Inflammopharmacology 17 2009 55 67
-
(2009)
Inflammopharmacology
, vol.17
, pp. 55-67
-
-
Harris, R.E.1
-
62
-
-
41349104451
-
Chemoprevention of colorectal neoplasia: The potential for personalized medicine
-
N. Arber, and B. Levin Chemoprevention of colorectal neoplasia: the potential for personalized medicine Gastroenterology 134 2008 1224 1237
-
(2008)
Gastroenterology
, vol.134
, pp. 1224-1237
-
-
Arber, N.1
Levin, B.2
-
63
-
-
77951630296
-
Primary prevention of colorectal cancer
-
A.T. Chan, and E.L. Giovannucci Primary prevention of colorectal cancer Gastroenterology 138 2029-43 2010 e10
-
(2010)
Gastroenterology
, vol.138
, Issue.2029-2043
, pp. 10
-
-
Chan, A.T.1
Giovannucci, E.L.2
-
64
-
-
0028576836
-
Sulindac and polyp regression
-
F.M. Giardiello Sulindac and polyp regression Cancer Metastasis Rev 13 1994 279 283
-
(1994)
Cancer Metastasis Rev
, vol.13
, pp. 279-283
-
-
Giardiello, F.M.1
-
65
-
-
0033594911
-
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
-
T.D. Warner, F. Giuliano, I. Vojnovic, A. Bukasa, J.A. Mitchell, and J.R. Vane Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis Proc Natl Acad Sci U S A 96 1999 7563 7568
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7563-7568
-
-
Warner, T.D.1
Giuliano, F.2
Vojnovic, I.3
Bukasa, A.4
Mitchell, J.A.5
Vane, J.R.6
-
67
-
-
42549150113
-
Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: Potential implications for cyclooxygenase-2 inhibition
-
E. Arehart, J. Stitham, F.W. Asselbergs, K. Douville, T. MacKenzie, and K.M. Fetalvero Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition Circ Res 102 2008 986 993
-
(2008)
Circ Res
, vol.102
, pp. 986-993
-
-
Arehart, E.1
Stitham, J.2
Asselbergs, F.W.3
Douville, K.4
MacKenzie, T.5
Fetalvero, K.M.6
-
68
-
-
39249083969
-
Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study
-
U. Vogel, J. Christensen, H. Wallin, S. Friis, B.A. Nexo, and O. Raaschou-Nielsen Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study Mutat Res 639 2008 89 100
-
(2008)
Mutat Res
, vol.639
, pp. 89-100
-
-
Vogel, U.1
Christensen, J.2
Wallin, H.3
Friis, S.4
Nexo, B.A.5
Raaschou-Nielsen, O.6
-
69
-
-
0034816925
-
Cyclooxygenase-independent actions of cyclooxygenase inhibitors
-
I. Tegeder, J. Pfeilschifter, and G. Geisslinger Cyclooxygenase- independent actions of cyclooxygenase inhibitors FASEB J 15 2001 2057 2072
-
(2001)
FASEB J
, vol.15
, pp. 2057-2072
-
-
Tegeder, I.1
Pfeilschifter, J.2
Geisslinger, G.3
-
70
-
-
3843138492
-
Evidence for colorectal cancer cell specificity of aspirin effects on NF kappa B signalling and apoptosis
-
F.V.N. Din, M.G. Dunlop, and L.A. Stark Evidence for colorectal cancer cell specificity of aspirin effects on NF kappa B signalling and apoptosis Br J Cancer 91 2004 381 388
-
(2004)
Br J Cancer
, vol.91
, pp. 381-388
-
-
Din, F.V.N.1
Dunlop, M.G.2
Stark, L.A.3
-
71
-
-
33847047461
-
Epigenetics: A landscape takes shape
-
A.D. Goldberg, C.D. Allis, and E. Bernstein Epigenetics: a landscape takes shape Cell 128 2007 635 638
-
(2007)
Cell
, vol.128
, pp. 635-638
-
-
Goldberg, A.D.1
Allis, C.D.2
Bernstein, E.3
-
72
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
M. Esteller Cancer epigenomics: DNA methylomes and histone-modification maps Nat Rev Genet 8 2007 286 298
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
73
-
-
33847065486
-
The epigenomics of cancer
-
P.A. Jones, and S.B. Baylin The epigenomics of cancer Cell 128 2007 683 692
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
74
-
-
85015069067
-
Controlling the double helix
-
G. Felsenfeld, and M. Groudine Controlling the double helix Nature 421 2003 448 453
-
(2003)
Nature
, vol.421
, pp. 448-453
-
-
Felsenfeld, G.1
Groudine, M.2
-
75
-
-
77957970301
-
Epigenetic modifications and human disease
-
A. Portela, and M. Esteller Epigenetic modifications and human disease Nat Biotechnol 28 2010 1057 1068
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
76
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
A. Bird DNA methylation patterns and epigenetic memory Genes Dev 16 2002 6 21
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
77
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
M.G. Goll, and T.H. Bestor Eukaryotic cytosine methyltransferases Annu Rev Biochem 74 2005 481 514
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 481-514
-
-
Goll, M.G.1
Bestor, T.H.2
-
78
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
P.A. Jones, and D. Takai The role of DNA methylation in mammalian epigenetics Science 293 2001 1068 1070
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
79
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
R. Jaenisch, and A. Bird Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals Nat Genet 33 Suppl 2003 245 254
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
80
-
-
77957940722
-
The NIH roadmap epigenomics mapping consortium
-
B.E. Bernstein, J.A. Stamatoyannopoulos, J.F. Costello, B. Ren, A. Milosavljevic, and A. Meissner The NIH roadmap epigenomics mapping consortium Nat Biotechnol 28 2010 1045 1048
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1045-1048
-
-
Bernstein, B.E.1
Stamatoyannopoulos, J.A.2
Costello, J.F.3
Ren, B.4
Milosavljevic, A.5
Meissner, A.6
-
81
-
-
34249275353
-
Phenotypic plasticity and the epigenetics of human disease
-
A.P. Feinberg Phenotypic plasticity and the epigenetics of human disease Nature 447 2007 433 440
-
(2007)
Nature
, vol.447
, pp. 433-440
-
-
Feinberg, A.P.1
-
82
-
-
59149084538
-
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
-
R.A. Irizarry, C. Ladd-Acosta, B. Wen, Z. Wu, C. Montano, and P. Onyango The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores Nat Genet 41 2009 178 186
-
(2009)
Nat Genet
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
-
83
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
A. Doi, I.H. Park, B. Wen, P. Murakami, M.J. Aryee, and R. Irizarry Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts Nat Genet 2009
-
(2009)
Nat Genet
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
Murakami, P.4
Aryee, M.J.5
Irizarry, R.6
-
84
-
-
1042278765
-
The history of cancer epigenetics
-
A.P. Feinberg, and B. Tycko The history of cancer epigenetics Nat Rev Cancer 4 2004 143 153
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
85
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
J.G. Herman, and S.B. Baylin Gene silencing in cancer in association with promoter hypermethylation N Engl J Med 349 2003 2042 2054
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
86
-
-
40849139208
-
Epigenetics in cancer
-
M. Esteller Epigenetics in cancer N Engl J Med 358 2008 1148 1159
-
(2008)
N Engl J Med
, vol.358
, pp. 1148-1159
-
-
Esteller, M.1
-
87
-
-
0037068353
-
DNA methylation in cancer: Too much, but also too little
-
M. Ehrlich DNA methylation in cancer: too much, but also too little Oncogene 21 2002 5400 5413
-
(2002)
Oncogene
, vol.21
, pp. 5400-5413
-
-
Ehrlich, M.1
-
88
-
-
79952534189
-
Regulation of chromatin by histone modifications
-
A.J. Bannister, and T. Kouzarides Regulation of chromatin by histone modifications Cell Res 21 2011 381 395
-
(2011)
Cell Res
, vol.21
, pp. 381-395
-
-
Bannister, A.J.1
Kouzarides, T.2
-
89
-
-
33847076849
-
Chromatin modifications and their function
-
T. Kouzarides Chromatin modifications and their function Cell 128 2007 693 705
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
90
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
B.E. Bernstein, T.S. Mikkelsen, X. Xie, M. Kamal, D.J. Huebert, and J. Cuff A bivalent chromatin structure marks key developmental genes in embryonic stem cells Cell 125 2006 315 326
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
-
92
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
M. Widschwendter, H. Fiegl, D. Egle, E. Mueller-Holzner, G. Spizzo, and C. Marth Epigenetic stem cell signature in cancer Nat Genet 39 2007 157 158
-
(2007)
Nat Genet
, vol.39
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
Mueller-Holzner, E.4
Spizzo, G.5
Marth, C.6
-
93
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
J.E. Ohm, K.M. McGarvey, X. Yu, L. Cheng, K.E. Schuebel, and L. Cope A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing Nat Genet 39 2007 237 242
-
(2007)
Nat Genet
, vol.39
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
Cheng, L.4
Schuebel, K.E.5
Cope, L.6
-
94
-
-
58149395035
-
Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells
-
J. Rodriguez, M. Muñoz, L. Vives, C.G. Frangou, M. Groudine, and M.A. Peinado Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells Proc Natl Acad Sci U S A 105 2008 19809 19814
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19809-19814
-
-
Rodriguez, J.1
Muñoz, M.2
Vives, L.3
Frangou, C.G.4
Groudine, M.5
Peinado, M.A.6
-
95
-
-
0033894117
-
Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors
-
M. Toyota, L. Shen, M. Ohe-Toyota, S.R. Hamilton, F.A. Sinicrope, and J.P. Issa Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors Cancer Res 60 2000 4044 4048
-
(2000)
Cancer Res
, vol.60
, pp. 4044-4048
-
-
Toyota, M.1
Shen, L.2
Ohe-Toyota, M.3
Hamilton, S.R.4
Sinicrope, F.A.5
Issa, J.P.6
-
96
-
-
0035360797
-
Transcriptional silencing of cyclooxygenase-2 by hyper-methylation of the 5′ CpG island in human gastric carcinoma cells
-
S.H. Song, H.S. Jong, H.H. Choi, H. Inoue, T. Tanabe, and N.K. Kim Transcriptional silencing of cyclooxygenase-2 by hyper-methylation of the 5′ CpG island in human gastric carcinoma cells Cancer Res 61 2001 4628 4635
-
(2001)
Cancer Res
, vol.61
, pp. 4628-4635
-
-
Song, S.H.1
Jong, H.S.2
Choi, H.H.3
Inoue, H.4
Tanabe, T.5
Kim, N.K.6
-
97
-
-
77954954112
-
Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas
-
J.C. Kim, J.S. Choi, S.A. Roh, D.H. Cho, T.W. Kim, and Y.S. Kim Promoter methylation of specific genes is associated with the phenotype and progression of colorectal adenocarcinomas Ann Surg Oncol 17 2010 1767 1776
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 1767-1776
-
-
Kim, J.C.1
Choi, J.S.2
Roh, S.A.3
Cho, D.H.4
Kim, T.W.5
Kim, Y.S.6
-
98
-
-
79960024752
-
COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status
-
A.G. Asting, H. Caren, M. Andersson, C. Lonnroth, K. Lagerstedt, and K. Lundholm COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status BMC Cancer 11 2011 238
-
(2011)
BMC Cancer
, vol.11
, pp. 238
-
-
Asting, A.G.1
Caren, H.2
Andersson, M.3
Lonnroth, C.4
Lagerstedt, K.5
Lundholm, K.6
-
99
-
-
0037137871
-
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer
-
T. Kikuchi, F. Itoh, M. Toyota, H. Suzuki, H. Yamamoto, and M. Fujita Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer Int J Cancer 97 2002 272 277
-
(2002)
Int J Cancer
, vol.97
, pp. 272-277
-
-
Kikuchi, T.1
Itoh, F.2
Toyota, M.3
Suzuki, H.4
Yamamoto, H.5
Fujita, M.6
-
100
-
-
7044245949
-
Promoter methylation regulates cyclooxygenase expression in breast cancer
-
X. Ma, Q. Yang, K.T. Wilson, N. Kundu, S.J. Meltzer, and A.M. Fulton Promoter methylation regulates cyclooxygenase expression in breast cancer Breast Cancer Res 6 2004 R316 R321
-
(2004)
Breast Cancer Res
, vol.6
-
-
Ma, X.1
Yang, Q.2
Wilson, K.T.3
Kundu, N.4
Meltzer, S.J.5
Fulton, A.M.6
-
101
-
-
33644601609
-
Aberrant methylation of cyclooxygenase-2 in breast cancer patients
-
L.W.C. Chow, L. Zhu, W.T.Y. Loo, and E.L.H. Lui Aberrant methylation of cyclooxygenase-2 in breast cancer patients Biomed Pharmacother 59 Suppl 2 2005 S264 S267
-
(2005)
Biomed Pharmacother
, vol.59
, Issue.SUPPL. 2
-
-
Chow, L.W.C.1
Zhu, L.2
Loo, W.T.Y.3
Lui, E.L.H.4
-
102
-
-
3543100257
-
Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells
-
H. Murata, S. Tsuji, M. Tsujii, Y. Sakaguchi, H.Y. Fu, and S. Kawano Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells Lab Invest 84 2004 1050 1059
-
(2004)
Lab Invest
, vol.84
, pp. 1050-1059
-
-
Murata, H.1
Tsuji, S.2
Tsujii, M.3
Sakaguchi, Y.4
Fu, H.Y.5
Kawano, S.6
-
103
-
-
40949161396
-
Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma
-
N. Nishida, T. Nagasaka, T. Nishimura, I. Ikai, C.R. Boland, and A. Goel Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma Hepatology 47 2008 908 918
-
(2008)
Hepatology
, vol.47
, pp. 908-918
-
-
Nishida, N.1
Nagasaka, T.2
Nishimura, T.3
Ikai, I.4
Boland, C.R.5
Goel, A.6
-
104
-
-
79954692738
-
Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis
-
T.H. Um, H. Kim, B.K. Oh, M.S. Kim, K.S. Kim, and G. Jung Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis J Hepatol 54 2011 939 947
-
(2011)
J Hepatol
, vol.54
, pp. 939-947
-
-
Um, T.H.1
Kim, H.2
Oh, B.K.3
Kim, M.S.4
Kim, K.S.5
Jung, G.6
-
105
-
-
13444309421
-
Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with epidermal growth factor receptor expression
-
R. Soo, T. Putti, Q. Tao, B.-C. Goh, K.-H. Lee, and L. Kwok-Seng Overexpression of cyclooxygenase-2 in nasopharyngeal carcinoma and association with epidermal growth factor receptor expression Arch Otolaryngol Head Neck Surg 131 2005 147 152
-
(2005)
Arch Otolaryngol Head Neck Surg
, vol.131
, pp. 147-152
-
-
Soo, R.1
Putti, T.2
Tao, Q.3
Goh, B.-C.4
Lee, K.-H.5
Kwok-Seng, L.6
-
106
-
-
33846221516
-
Prognostic value of CpG island hypermethylation at PTGS2, RAR-beta, EDNRB, and other gene loci in patients undergoing radical prostatectomy
-
P.J. Bastian, J. Ellinger, L.C. Heukamp, P. Kahl, S.C. Müller, and A. von Rücker Prognostic value of CpG island hypermethylation at PTGS2, RAR-beta, EDNRB, and other gene loci in patients undergoing radical prostatectomy Eur Urol 51 2007 665 674
-
(2007)
Eur Urol
, vol.51
, pp. 665-674
-
-
Bastian, P.J.1
Ellinger, J.2
Heukamp, L.C.3
Kahl, P.4
Müller, S.C.5
Von Rücker, A.6
-
107
-
-
20144383392
-
Functional epigenomics identifies genes frequently silenced in prostate cancer
-
D. Lodygin, A. Epanchintsev, A. Menssen, J. Diebold, and H. Hermeking Functional epigenomics identifies genes frequently silenced in prostate cancer Cancer Res 65 2005 4218 4227
-
(2005)
Cancer Res
, vol.65
, pp. 4218-4227
-
-
Lodygin, D.1
Epanchintsev, A.2
Menssen, A.3
Diebold, J.4
Hermeking, H.5
-
108
-
-
47749106026
-
COX-2 (PTGS2) gene methylation in epithelial, subepithelial lymphocyte and stromal tissue compartments in a spectrum of esophageal squamous neoplasia
-
S.P. Dawsey, M.J. Roth, L. Adams, N. Hu, Q.-H. Wang, and P.R. Taylor COX-2 (PTGS2) gene methylation in epithelial, subepithelial lymphocyte and stromal tissue compartments in a spectrum of esophageal squamous neoplasia Cancer Detect Prev 32 2008 135 139
-
(2008)
Cancer Detect Prev
, vol.32
, pp. 135-139
-
-
Dawsey, S.P.1
Roth, M.J.2
Adams, L.3
Hu, N.4
Wang, Q.-H.5
Taylor, P.R.6
-
109
-
-
80051703608
-
Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma
-
X.Y. Meng, S.T. Zhu, Y. Zong, Y.J. Wang, P. Li, and S.T. Zhang Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma Dis Esophagus 24 2011 444 449
-
(2011)
Dis Esophagus
, vol.24
, pp. 444-449
-
-
Meng, X.Y.1
Zhu, S.T.2
Zong, Y.3
Wang, Y.J.4
Li, P.5
Zhang, S.T.6
-
110
-
-
77953783396
-
Cyclooxygenase-deficient pancreatic cancer cells use exogenous sources of prostaglandins
-
N. Omura, M. Griffith, A. Vincent, A. Li, S.-M. Hong, and K. Walter Cyclooxygenase-deficient pancreatic cancer cells use exogenous sources of prostaglandins Mol Cancer Res 8 2010 821 832
-
(2010)
Mol Cancer Res
, vol.8
, pp. 821-832
-
-
Omura, N.1
Griffith, M.2
Vincent, A.3
Li, A.4
Hong, S.-M.5
Walter, K.6
-
111
-
-
34248578815
-
Cyclooxygenase-2 transcription is regulated by human papillomavirus 16 E6 and E7 oncoproteins: Evidence of a corepressor/coactivator exchange
-
K. Subbaramaiah, and A.J. Dannenberg Cyclooxygenase-2 transcription is regulated by human papillomavirus 16 E6 and E7 oncoproteins: evidence of a corepressor/coactivator exchange Cancer Res 67 2007 3976 3985
-
(2007)
Cancer Res
, vol.67
, pp. 3976-3985
-
-
Subbaramaiah, K.1
Dannenberg, A.J.2
-
112
-
-
0035126879
-
Cyclooxygenase-2 is overexpressed in human cervical cancer
-
S. Kulkarni, J.S. Rader, F. Zhang, H. Liapis, A.T. Koki, and J.L. Masferrer Cyclooxygenase-2 is overexpressed in human cervical cancer Clin Cancer Res 7 2001 429 434
-
(2001)
Clin Cancer Res
, vol.7
, pp. 429-434
-
-
Kulkarni, S.1
Rader, J.S.2
Zhang, F.3
Liapis, H.4
Koki, A.T.5
Masferrer, J.L.6
-
113
-
-
0034011262
-
High cyclooxygenase-2 expression in stage IB cervical cancer with lymph node metastasis or parametrial invasion
-
H.S. Ryu, K.H. Chang, H.W. Yang, M.S. Kim, H.C. Kwon, and K.S. Oh High cyclooxygenase-2 expression in stage IB cervical cancer with lymph node metastasis or parametrial invasion Gynecol Oncol 76 2000 320 325
-
(2000)
Gynecol Oncol
, vol.76
, pp. 320-325
-
-
Ryu, H.S.1
Chang, K.H.2
Yang, H.W.3
Kim, M.S.4
Kwon, H.C.5
Oh, K.S.6
-
114
-
-
77955277307
-
Bcr-Abl-independent mechanism of resistance to imatinib in K562 cells: Induction of cyclooxygenase-2 (COX-2) by histone deacetylases (HDACs)
-
A.M. Kalle, S. Sachchidanand, and R. Pallu Bcr-Abl-independent mechanism of resistance to imatinib in K562 cells: induction of cyclooxygenase-2 (COX-2) by histone deacetylases (HDACs) Leuk Res 34 2010 1132 1138
-
(2010)
Leuk Res
, vol.34
, pp. 1132-1138
-
-
Kalle, A.M.1
Sachchidanand, S.2
Pallu, R.3
-
115
-
-
18144381890
-
Cyclooxygenase-2 regulation in colon cancer cells: Modulation of RNA polymerase II elongation by histone deacetylase inhibitors
-
X. Tong, L. Yin, S. Joshi, D.W. Rosenberg, and C. Giardina Cyclooxygenase-2 regulation in colon cancer cells: modulation of RNA polymerase II elongation by histone deacetylase inhibitors J Biol Chem 280 2005 15503 15509
-
(2005)
J Biol Chem
, vol.280
, pp. 15503-15509
-
-
Tong, X.1
Yin, L.2
Joshi, S.3
Rosenberg, D.W.4
Giardina, C.5
-
116
-
-
31544461563
-
High-resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histologic and genetic subgroups of invasive breast cancer
-
D.E. Stange, B. Radlwimmer, F. Schubert, F. Traub, A. Pich, and G. Toedt High-resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histologic and genetic subgroups of invasive breast cancer Clin Cancer Res 12 2006 345 352
-
(2006)
Clin Cancer Res
, vol.12
, pp. 345-352
-
-
Stange, D.E.1
Radlwimmer, B.2
Schubert, F.3
Traub, F.4
Pich, A.5
Toedt, G.6
-
117
-
-
0032995903
-
Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis
-
S. Fu, K.S. Ramanujam, A. Wong, G.T. Fantry, C.B. Drachenberg, and S.P. James Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis Gastroenterology 116 1999 1319 1329
-
(1999)
Gastroenterology
, vol.116
, pp. 1319-1329
-
-
Fu, S.1
Ramanujam, K.S.2
Wong, A.3
Fantry, G.T.4
Drachenberg, C.B.5
James, S.P.6
-
118
-
-
0035866790
-
Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells
-
M. Akhtar, Y. Cheng, R.M. Magno, H. Ashktorab, D.T. Smoot, and S.J. Meltzer Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells Cancer Res 61 2001 2399 2403
-
(2001)
Cancer Res
, vol.61
, pp. 2399-2403
-
-
Akhtar, M.1
Cheng, Y.2
Magno, R.M.3
Ashktorab, H.4
Smoot, D.T.5
Meltzer, S.J.6
-
119
-
-
78751580387
-
Chromatin and DNA methylation dynamics of Helicobacter pylori-induced COX-2 activation
-
R. Pero, S. Peluso, T. Angrisano, C. Tuccillo, S. Sacchetti, and S. Keller Chromatin and DNA methylation dynamics of Helicobacter pylori-induced COX-2 activation Int J Med Microbiol 301 2011 140 149
-
(2011)
Int J Med Microbiol
, vol.301
, pp. 140-149
-
-
Pero, R.1
Peluso, S.2
Angrisano, T.3
Tuccillo, C.4
Sacchetti, S.5
Keller, S.6
-
120
-
-
36849003543
-
Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer
-
M.F.G. de Maat, C.J.H. van de Velde, N. Umetani, P. de Heer, H. Putter, and A.Q. van Hoesel Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer J Clin Oncol 25 2007 4887 4894
-
(2007)
J Clin Oncol
, vol.25
, pp. 4887-4894
-
-
De Maat, M.F.G.1
Van De Velde, C.J.H.2
Umetani, N.3
De Heer, P.4
Putter, H.5
Van Hoesel, A.Q.6
-
121
-
-
51249107541
-
Serum free DNA and COX-2 mRNA expression in peripheral blood for lung cancer detection
-
P. Ulivi, L. Mercatali, W. Zoli, D. Dell'amore, V. Poletti, and G.L. Casoni Serum free DNA and COX-2 mRNA expression in peripheral blood for lung cancer detection Thorax 63 2008 843 844
-
(2008)
Thorax
, vol.63
, pp. 843-844
-
-
Ulivi, P.1
Mercatali, L.2
Zoli, W.3
Dell'Amore, D.4
Poletti, V.5
Casoni, G.L.6
-
122
-
-
4143075835
-
Potential usefulness of detecting cyclooxygenase 2 messenger RNA in feces for colorectal cancer screening
-
S. Kanaoka, K. Yoshida, N. Miura, H. Sugimura, and M. Kajimura Potential usefulness of detecting cyclooxygenase 2 messenger RNA in feces for colorectal cancer screening Gastroenterology 127 2004 422 427
-
(2004)
Gastroenterology
, vol.127
, pp. 422-427
-
-
Kanaoka, S.1
Yoshida, K.2
Miura, N.3
Sugimura, H.4
Kajimura, M.5
-
123
-
-
34247882544
-
Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps
-
W.K. Leung, K.-F. To, E.P.S. Man, M.W.Y. Chan, A.J. Hui, and S.S.M. Ng Detection of hypermethylated DNA or cyclooxygenase-2 messenger RNA in fecal samples of patients with colorectal cancer or polyps Am J Gastroenterol 102 2007 1070 1076
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 1070-1076
-
-
Leung, W.K.1
To, K.-F.2
Man, E.P.S.3
Chan, M.W.Y.4
Hui, A.J.5
Ng, S.S.M.6
-
124
-
-
84866126280
-
The use of molecular markers as a method to predict the response to neoadjuvant therapy for advanced stage rectal adenocarcinoma
-
Y. Edden, S.D. Wexner, and M. Berho The use of molecular markers as a method to predict the response to neoadjuvant therapy for advanced stage rectal adenocarcinoma Colorectal Dis 2011
-
(2011)
Colorectal Dis
-
-
Edden, Y.1
Wexner, S.D.2
Berho, M.3
-
125
-
-
62349138124
-
The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
-
A. Greenhough, H.J.M. Smartt, A.E. Moore, H.R. Roberts, A.C. Williams, and C. Paraskeva The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment Carcinogenesis 30 2009 377 386
-
(2009)
Carcinogenesis
, vol.30
, pp. 377-386
-
-
Greenhough, A.1
Smartt, H.J.M.2
Moore, A.E.3
Roberts, H.R.4
Williams, A.C.5
Paraskeva, C.6
-
126
-
-
0027371123
-
Altered eicosanoid levels in human colon cancer
-
B. Rigas, I.S. Goldman, and L. Levine Altered eicosanoid levels in human colon cancer J Lab Clin Med 122 1993 518 523
-
(1993)
J Lab Clin Med
, vol.122
, pp. 518-523
-
-
Rigas, B.1
Goldman, I.S.2
Levine, L.3
-
127
-
-
0028261042
-
Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2
-
S. Pugh, and G.A. Thomas Patients with adenomatous polyps and carcinomas have increased colonic mucosal prostaglandin E2 Gut 35 1994 675 678
-
(1994)
Gut
, vol.35
, pp. 675-678
-
-
Pugh, S.1
Thomas, G.A.2
-
128
-
-
59449084521
-
Prognostic role of PGE2 receptor EP2 in esophageal squamous cell carcinoma
-
K.-T. Kuo, H.-W. Wang, T.-Y. Chou, W.-H. Hsu, H.-S. Hsu, and C.-H. Lin Prognostic role of PGE2 receptor EP2 in esophageal squamous cell carcinoma Ann Surg Oncol 16 2009 352 360
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 352-360
-
-
Kuo, K.-T.1
Wang, H.-W.2
Chou, T.-Y.3
Hsu, W.-H.4
Hsu, H.-S.5
Lin, C.-H.6
-
129
-
-
33847421749
-
Inverse correlation between serum PGE2 and T classification in head and neck cancer
-
M. Hambek, M. Baghi, J. Wagenblast, J. Schmitt, H. Baumann, and R. Knecht Inverse correlation between serum PGE2 and T classification in head and neck cancer Head Neck 29 2007 244 248
-
(2007)
Head Neck
, vol.29
, pp. 244-248
-
-
Hambek, M.1
Baghi, M.2
Wagenblast, J.3
Schmitt, J.4
Baumann, H.5
Knecht, R.6
-
130
-
-
0038309422
-
Enhancement of colon carcinogenesis by prostaglandin E2 administration
-
T. Kawamori, N. Uchiya, T. Sugimura, and K. Wakabayashi Enhancement of colon carcinogenesis by prostaglandin E2 administration Carcinogenesis 24 2003 985 990
-
(2003)
Carcinogenesis
, vol.24
, pp. 985-990
-
-
Kawamori, T.1
Uchiya, N.2
Sugimura, T.3
Wakabayashi, K.4
-
131
-
-
0037081178
-
Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice
-
M.B. Hansen-Petrik, M.F. McEntee, B. Jull, H. Shi, M.B. Zemel, and J. Whelan Prostaglandin E(2) protects intestinal tumors from nonsteroidal anti-inflammatory drug-induced regression in Apc(Min/+) mice Cancer Res 62 2002 403 408
-
(2002)
Cancer Res
, vol.62
, pp. 403-408
-
-
Hansen-Petrik, M.B.1
McEntee, M.F.2
Jull, B.3
Shi, H.4
Zemel, M.B.5
Whelan, J.6
-
132
-
-
0038482089
-
Potential role of microsomal prostaglandin e synthase-1 in tumorigenesis
-
D. Kamei, M. Murakami, Y. Nakatani, Y. Ishikawa, T. Ishii, and I. Kudo Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis J Biol Chem 278 2003 19396 19405
-
(2003)
J Biol Chem
, vol.278
, pp. 19396-19405
-
-
Kamei, D.1
Murakami, M.2
Nakatani, Y.3
Ishikawa, Y.4
Ishii, T.5
Kudo, I.6
-
133
-
-
0034813862
-
Inducible prostaglandin e synthase is overexpressed in non-small cell lung cancer
-
K. Yoshimatsu, N.K. Altorki, D. Golijanin, F. Zhang, P.J. Jakobsson, and A.J. Dannenberg Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer Clin Cancer Res 7 2001 2669 2674
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2669-2674
-
-
Yoshimatsu, K.1
Altorki, N.K.2
Golijanin, D.3
Zhang, F.4
Jakobsson, P.J.5
Dannenberg, A.J.6
-
134
-
-
0035674730
-
Inducible microsomal prostaglandin e synthase is overexpressed in colorectal adenomas and cancer
-
K. Yoshimatsu, D. Golijanin, P.B. Paty, R.A. Soslow, P.J. Jakobsson, and R.A. DeLellis Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer Clin Cancer Res 7 2001 3971 3976
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3971-3976
-
-
Yoshimatsu, K.1
Golijanin, D.2
Paty, P.B.3
Soslow, R.A.4
Jakobsson, P.J.5
Delellis, R.A.6
-
135
-
-
36549072921
-
Clinical significance of prostaglandin e synthase expression in gastric cancer tissue
-
K. Gudis, A. Tatsuguchi, K. Wada, T. Hiratsuka, S. Futagami, and Y. Fukuda Clinical significance of prostaglandin E synthase expression in gastric cancer tissue Hum Pathol 38 2007 1826 1835
-
(2007)
Hum Pathol
, vol.38
, pp. 1826-1835
-
-
Gudis, K.1
Tatsuguchi, A.2
Wada, K.3
Hiratsuka, T.4
Futagami, S.5
Fukuda, Y.6
-
136
-
-
55949098253
-
Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers
-
S. Hasan, M. Satake, D.W. Dawson, H. Funahashi, E. Angst, and V.L.W. Go Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers Pancreas 37 2008 121 127
-
(2008)
Pancreas
, vol.37
, pp. 121-127
-
-
Hasan, S.1
Satake, M.2
Dawson, D.W.3
Funahashi, H.4
Angst, E.5
Go, V.L.W.6
-
137
-
-
59449100165
-
High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells
-
M. Herfs, L. Herman, P. Hubert, F. Minner, M. Arafa, and P. Roncarati High expression of PGE2 enzymatic pathways in cervical (pre)neoplastic lesions and functional consequences for antigen-presenting cells Cancer Immunol Immunother 58 2009 603 614
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 603-614
-
-
Herfs, M.1
Herman, L.2
Hubert, P.3
Minner, F.4
Arafa, M.5
Roncarati, P.6
-
138
-
-
73249123772
-
Microsomal prostaglandin e synthase 1 determines tumor growth in vivo of prostate and lung cancer cells
-
H. Hanaka, S.-C. Pawelzik, J.I. Johnsen, M. Rakonjac, K. Terawaki, and A. Rasmuson Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells Proc Natl Acad Sci U S A 106 2009 18757 18762
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 18757-18762
-
-
Hanaka, H.1
Pawelzik, S.-C.2
Johnsen, J.I.3
Rakonjac, M.4
Terawaki, K.5
Rasmuson, A.6
-
139
-
-
70349488360
-
Immunohistochemical demonstration of membrane-bound prostaglandin E2 synthase-1 in papillary thyroid carcinoma
-
Y. Omi, N. Shibata, T. Okamoto, T. Obara, and M. Kobayashi Immunohistochemical demonstration of membrane-bound prostaglandin E2 synthase-1 in papillary thyroid carcinoma Acta Histochem Cytochem 42 2009 105 109
-
(2009)
Acta Histochem Cytochem
, vol.42
, pp. 105-109
-
-
Omi, Y.1
Shibata, N.2
Okamoto, T.3
Obara, T.4
Kobayashi, M.5
-
140
-
-
56149086145
-
Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets
-
N. Baryawno, B. Sveinbjörnsson, S. Eksborg, A. Orrego, L. Segerström, and C.O. Oqvist Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targets Neuro-oncol 10 2008 661 674
-
(2008)
Neuro-oncol
, vol.10
, pp. 661-674
-
-
Baryawno, N.1
Sveinbjörnsson, B.2
Eksborg, S.3
Orrego, A.4
Segerström, L.5
Oqvist, C.O.6
-
141
-
-
62749133492
-
The terminal prostaglandin synthases mPGES-1, mPGES-2, and cPGES are all overexpressed in human gliomas
-
S. Mattila, H. Tuominen, J. Koivukangas, and F. Stenbäck The terminal prostaglandin synthases mPGES-1, mPGES-2, and cPGES are all overexpressed in human gliomas Neuropathology 29 2009 156 165
-
(2009)
Neuropathology
, vol.29
, pp. 156-165
-
-
Mattila, S.1
Tuominen, H.2
Koivukangas, J.3
Stenbäck, F.4
-
142
-
-
77950092443
-
Expression of cyclooxygenase-2 and microsomal prostagalandin e synthase-1 in head and neck squamous cell carcinoma
-
R. Kawata, S. Hyo, M. Araki, and H. Takenaka Expression of cyclooxygenase-2 and microsomal prostagalandin E synthase-1 in head and neck squamous cell carcinoma Auris Nasus Larynx 37 2010 482 487
-
(2010)
Auris Nasus Larynx
, vol.37
, pp. 482-487
-
-
Kawata, R.1
Hyo, S.2
Araki, M.3
Takenaka, H.4
-
143
-
-
51949107285
-
Prostaglandin E(2) pathway in head and neck squamous cell carcinoma
-
M. Camacho, X. León, M.-T. Fernández-Figueras, M. Quer, and L. Vila Prostaglandin E(2) pathway in head and neck squamous cell carcinoma Head Neck 30 2008 1175 1181
-
(2008)
Head Neck
, vol.30
, pp. 1175-1181
-
-
Camacho, M.1
León, X.2
Fernández-Figueras, M.-T.3
Quer, M.4
Vila, L.5
-
144
-
-
44849085464
-
Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis
-
M. Nakanishi, D.C. Montrose, P. Clark, P.R. Nambiar, G.S. Belinsky, and K.P. Claffey Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis Cancer Res 68 2008 3251 3259
-
(2008)
Cancer Res
, vol.68
, pp. 3251-3259
-
-
Nakanishi, M.1
Montrose, D.C.2
Clark, P.3
Nambiar, P.R.4
Belinsky, G.S.5
Claffey, K.P.6
-
145
-
-
84863557324
-
Microsomal prostaglandin e synthase-1 is involved in multiple steps of colon carcinogenesis
-
Y. Sasaki, D. Kamei, Y. Ishikawa, T. Ishii, S. Uematsu, and S. Akira Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis Oncogene 2011
-
(2011)
Oncogene
-
-
Sasaki, Y.1
Kamei, D.2
Ishikawa, Y.3
Ishii, T.4
Uematsu, S.5
Akira, S.6
-
146
-
-
37349036468
-
DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721
-
H. Fan, Z. Zhao, Y. Quan, J. Xu, J. Zhang, and W. Xie DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721 Eur J Gastroenterol Hepatol 19 2007 952 961
-
(2007)
Eur J Gastroenterol Hepatol
, vol.19
, pp. 952-961
-
-
Fan, H.1
Zhao, Z.2
Quan, Y.3
Xu, J.4
Zhang, J.5
Xie, W.6
-
147
-
-
64549101212
-
Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis
-
M. Alaa, M. Suzuki, M. Yoshino, L. Tian, H. Suzuki, and K. Nagato Prostaglandin E2 receptor 2 overexpression in squamous cell carcinoma of the lung correlates with p16INK4A methylation and an unfavorable prognosis Int J Oncol 34 2009 805 812
-
(2009)
Int J Oncol
, vol.34
, pp. 805-812
-
-
Alaa, M.1
Suzuki, M.2
Yoshino, M.3
Tian, L.4
Suzuki, H.5
Nagato, K.6
-
148
-
-
77949741505
-
PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype
-
Y. Baba, K. Nosho, K. Shima, W. Goessling, A.T. Chan, and K. Ng PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype Cancer Epidemiol Biomarkers Prev 19 2010 822 831
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 822-831
-
-
Baba, Y.1
Nosho, K.2
Shima, K.3
Goessling, W.4
Chan, A.T.5
Ng, K.6
-
149
-
-
70249092519
-
The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development
-
K.-S. Chun, H.-C. Lao, C.S. Trempus, M. Okada, and R. Langenbach The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development Carcinogenesis 30 2009 1620 1627
-
(2009)
Carcinogenesis
, vol.30
, pp. 1620-1627
-
-
Chun, K.-S.1
Lao, H.-C.2
Trempus, C.S.3
Okada, M.4
Langenbach, R.5
-
150
-
-
77951722799
-
Piracy of prostaglandin E2/EP receptor-mediated signaling by Kaposi's sarcoma-associated herpes virus (HHV-8) for latency gene expression: Strategy of a successful pathogen
-
A.G. Paul, N. Sharma-Walia, N. Kerur, C. White, and B. Chandran Piracy of prostaglandin E2/EP receptor-mediated signaling by Kaposi's sarcoma-associated herpes virus (HHV-8) for latency gene expression: strategy of a successful pathogen Cancer Res 70 2010 3697 3708
-
(2010)
Cancer Res
, vol.70
, pp. 3697-3708
-
-
Paul, A.G.1
Sharma-Walia, N.2
Kerur, N.3
White, C.4
Chandran, B.5
-
151
-
-
36349009317
-
Epigenetic silencing of prostaglandin e receptor 2 (PTGER2) is associated with progression of neuroblastomas
-
Y. Sugino, A. Misawa, J. Inoue, M. Kitagawa, H. Hosoi, and T. Sugimoto Epigenetic silencing of prostaglandin E receptor 2 (PTGER2) is associated with progression of neuroblastomas Oncogene 26 2007 7401 7413
-
(2007)
Oncogene
, vol.26
, pp. 7401-7413
-
-
Sugino, Y.1
Misawa, A.2
Inoue, J.3
Kitagawa, M.4
Hosoi, H.5
Sugimoto, T.6
-
152
-
-
53149129417
-
Clinical significance of aberrant methylation of prostaglandin e receptor 2 (PTGER2) in nonsmall cell lung cancer: Association with prognosis, PTGER2 expression, and epidermal growth factor receptor mutation
-
L. Tian, M. Suzuki, T. Nakajima, R. Kubo, Y. Sekine, and K. Shibuya Clinical significance of aberrant methylation of prostaglandin E receptor 2 (PTGER2) in nonsmall cell lung cancer: association with prognosis, PTGER2 expression, and epidermal growth factor receptor mutation Cancer 113 2008 1396 1403
-
(2008)
Cancer
, vol.113
, pp. 1396-1403
-
-
Tian, L.1
Suzuki, M.2
Nakajima, T.3
Kubo, R.4
Sekine, Y.5
Shibuya, K.6
-
153
-
-
70449111359
-
Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications
-
S.G. Gray, N. Al-Sarraf, A.-M. Baird, M.-C. Cathcart, E. McGovern, and K.J. O'Byrne Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications Eur J Cancer 45 2009 3087 3097
-
(2009)
Eur J Cancer
, vol.45
, pp. 3087-3097
-
-
Gray, S.G.1
Al-Sarraf, N.2
Baird, A.-M.3
Cathcart, M.-C.4
McGovern, E.5
O'Byrne, K.J.6
-
154
-
-
81155149481
-
PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway
-
Y. Zhang, and Y. Daaka PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway Blood 118 2011 5355 5364
-
(2011)
Blood
, vol.118
, pp. 5355-5364
-
-
Zhang, Y.1
Daaka, Y.2
-
155
-
-
3042607782
-
Downregulation of prostaglandin e receptor subtype EP3 during colon cancer development
-
Y. Shoji, M. Takahashi, T. Kitamura, K. Watanabe, T. Kawamori, and T. Maruyama Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development Gut 53 2004 1151 1158
-
(2004)
Gut
, vol.53
, pp. 1151-1158
-
-
Shoji, Y.1
Takahashi, M.2
Kitamura, T.3
Watanabe, K.4
Kawamori, T.5
Maruyama, T.6
-
156
-
-
13544268334
-
15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer
-
M.G. Backlund, J.R. Mann, V.R. Holla, F.G. Buchanan, H.H. Tai, and E.S. Musiek 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer J Biol Chem 280 2005 3217 3223
-
(2005)
J Biol Chem
, vol.280
, pp. 3217-3223
-
-
Backlund, M.G.1
Mann, J.R.2
Holla, V.R.3
Buchanan, F.G.4
Tai, H.H.5
Musiek, E.S.6
-
157
-
-
30544448075
-
Chromosomal changes in colorectal adenomas: Relationship to gene mutations and potential for clinical utility
-
A. Leslie, A. Stewart, D.U. Baty, D. Mechan, L. McGreavey, and G. Smith Chromosomal changes in colorectal adenomas: relationship to gene mutations and potential for clinical utility Genes Chromosomes Cancer 45 2006 126 135
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 126-135
-
-
Leslie, A.1
Stewart, A.2
Baty, D.U.3
Mechan, D.4
McGreavey, L.5
Smith, G.6
-
158
-
-
58149461152
-
Decreased expression of 15-hydroxyprostaglandin dehydrogenase in gastric carcinomas
-
T.J. Jang, Y.S. Ji, and K.H. Jung Decreased expression of 15-hydroxyprostaglandin dehydrogenase in gastric carcinomas Yonsei Med J 49 2008 917 922
-
(2008)
Yonsei Med J
, vol.49
, pp. 917-922
-
-
Jang, T.J.1
Ji, Y.S.2
Jung, K.H.3
-
159
-
-
57249089707
-
NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer
-
D. Hughes, T. Otani, P. Yang, R.A. Newman, R.K. Yantiss, and N.K. Altorki NAD+-dependent 15-hydroxyprostaglandin dehydrogenase regulates levels of bioactive lipids in non-small cell lung cancer Cancer Prev Res (Phila) 1 2008 241 249
-
(2008)
Cancer Prev Res (Phila)
, vol.1
, pp. 241-249
-
-
Hughes, D.1
Otani, T.2
Yang, P.3
Newman, R.A.4
Yantiss, R.K.5
Altorki, N.K.6
-
160
-
-
68049101460
-
15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer
-
A. Thiel, A. Ganesan, J. Mrena, S. Junnila, A. Nykänen, and A. Hemmes 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer Clin Cancer Res 15 2009 4572 4580
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4572-4580
-
-
Thiel, A.1
Ganesan, A.2
Mrena, J.3
Junnila, S.4
Nykänen, A.5
Hemmes, A.6
-
161
-
-
80054711953
-
15-Hydroxyprostaglandin dehydrogenase as a novel molecular target for cancer chemoprevention and therapy
-
H.K. Na, J.M. Park, H.G. Lee, H.N. Lee, S.J. Myung, and Y.J. Surh 15-Hydroxyprostaglandin dehydrogenase as a novel molecular target for cancer chemoprevention and therapy Biochem Pharmacol 82 2011 1352 1360
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1352-1360
-
-
Na, H.K.1
Park, J.M.2
Lee, H.G.3
Lee, H.N.4
Myung, S.J.5
Surh, Y.J.6
-
162
-
-
56449114200
-
Repression of 15-hydroxyprostaglandin dehydrogenase involves histone deacetylase 2 and snail in colorectal cancer
-
M.G. Backlund, J.R. Mann, V.R. Holla, Q. Shi, T. Daikoku, and S.K. Dey Repression of 15-hydroxyprostaglandin dehydrogenase involves histone deacetylase 2 and snail in colorectal cancer Cancer Res 68 2008 9331 9337
-
(2008)
Cancer Res
, vol.68
, pp. 9331-9337
-
-
Backlund, M.G.1
Mann, J.R.2
Holla, V.R.3
Shi, Q.4
Daikoku, T.5
Dey, S.K.6
-
163
-
-
33747184291
-
Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells
-
M. Tong, Y. Ding, and H.-H. Tai Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells Biochem Pharmacol 72 2006 701 709
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 701-709
-
-
Tong, M.1
Ding, Y.2
Tai, H.-H.3
-
165
-
-
0032749227
-
Human prostacyclin synthase gene and hypertension: The Suita study
-
N. Iwai, T. Katsuya, K. Ishikawa, T. Mannami, J. Ogata, and J. Higaki Human prostacyclin synthase gene and hypertension: the Suita study Circulation 100 1999 2231 2236
-
(1999)
Circulation
, vol.100
, pp. 2231-2236
-
-
Iwai, N.1
Katsuya, T.2
Ishikawa, K.3
Mannami, T.4
Ogata, J.5
Higaki, J.6
-
166
-
-
0020586721
-
Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease
-
G.A. FitzGerald, A.K. Pedersen, and C. Patrono Analysis of prostacyclin and thromboxane biosynthesis in cardiovascular disease Circulation 67 1983 1174 1177
-
(1983)
Circulation
, vol.67
, pp. 1174-1177
-
-
Fitzgerald, G.A.1
Pedersen, A.K.2
Patrono, C.3
-
167
-
-
79953321199
-
Hypoxia upregulates PGI-synthase and increases PGI release in human vascular cells exposed to inflammatory stimuli
-
M. Camacho, C. Rodriguez, A. Guadall, S. Alcolea, M. Orriols, and J.R. Escudero Hypoxia upregulates PGI-synthase and increases PGI release in human vascular cells exposed to inflammatory stimuli J Lipid Res 52 2011 720 731
-
(2011)
J Lipid Res
, vol.52
, pp. 720-731
-
-
Camacho, M.1
Rodriguez, C.2
Guadall, A.3
Alcolea, S.4
Orriols, M.5
Escudero, J.R.6
-
168
-
-
0035824652
-
Prostacyclin-dependent apoptosis mediated by PPAR delta
-
T. Hatae, M. Wada, C. Yokoyama, M. Shimonishi, and T. Tanabe Prostacyclin-dependent apoptosis mediated by PPAR delta J Biol Chem 276 2001 46260 46267
-
(2001)
J Biol Chem
, vol.276
, pp. 46260-46267
-
-
Hatae, T.1
Wada, M.2
Yokoyama, C.3
Shimonishi, M.4
Tanabe, T.5
-
169
-
-
0036468255
-
Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer
-
R.L. Keith, Y.E. Miller, Y. Hoshikawa, M.D. Moore, T.L. Gesell, and B. Gao Manipulation of pulmonary prostacyclin synthase expression prevents murine lung cancer Cancer Res 62 2002 734 740
-
(2002)
Cancer Res
, vol.62
, pp. 734-740
-
-
Keith, R.L.1
Miller, Y.E.2
Hoshikawa, Y.3
Moore, M.D.4
Gesell, T.L.5
Gao, B.6
-
170
-
-
77956188663
-
Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression
-
R.L. Keith, V. Karoor, A.B. Mozer, T.M. Hudish, M. Le, and Y.E. Miller Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression Lung Cancer 70 2010 37 42
-
(2010)
Lung Cancer
, vol.70
, pp. 37-42
-
-
Keith, R.L.1
Karoor, V.2
Mozer, A.B.3
Hudish, T.M.4
Le, M.5
Miller, Y.E.6
-
171
-
-
4143070427
-
Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice
-
R.L. Keith, Y.E. Miller, T.M. Hudish, C.E. Girod, S. Sotto-Santiago, and W.A. Franklin Pulmonary prostacyclin synthase overexpression chemoprevents tobacco smoke lung carcinogenesis in mice Cancer Res 64 2004 5897 5904
-
(2004)
Cancer Res
, vol.64
, pp. 5897-5904
-
-
Keith, R.L.1
Miller, Y.E.2
Hudish, T.M.3
Girod, C.E.4
Sotto-Santiago, S.5
Franklin, W.A.6
-
172
-
-
57249089708
-
Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator-activated receptor gamma
-
R. Nemenoff, A.M. Meyer, T.M. Hudish, A.B. Mozer, A. Snee, and S. Narumiya Prostacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator-activated receptor gamma Cancer Prev Res (Phila) 1 2008 349 356
-
(2008)
Cancer Prev Res (Phila)
, vol.1
, pp. 349-356
-
-
Nemenoff, R.1
Meyer, A.M.2
Hudish, T.M.3
Mozer, A.B.4
Snee, A.5
Narumiya, S.6
-
173
-
-
1842611989
-
Prostacyclin induces apoptosis of vascular smooth muscle cells by a cAMP-mediated inhibition of extracellular signal-regulated kinase activity and can counteract the mitogenic activity of endothelin-1 or basic fibroblast growth factor
-
R.-C. Li, T. Cindrova-Davies, J.N. Skepper, and L.A. Sellers Prostacyclin induces apoptosis of vascular smooth muscle cells by a cAMP-mediated inhibition of extracellular signal-regulated kinase activity and can counteract the mitogenic activity of endothelin-1 or basic fibroblast growth factor Circ Res 94 2004 759 767
-
(2004)
Circ Res
, vol.94
, pp. 759-767
-
-
Li, R.-C.1
Cindrova-Davies, T.2
Skepper, J.N.3
Sellers, L.A.4
-
174
-
-
33645529116
-
Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps
-
E.M. Poole, J. Bigler, J. Whitton, J.G. Sibert, J.D. Potter, and C.M. Ulrich Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps Cancer Epidemiol Biomarkers Prev 15 2006 502 508
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 502-508
-
-
Poole, E.M.1
Bigler, J.2
Whitton, J.3
Sibert, J.G.4
Potter, J.D.5
Ulrich, C.M.6
-
175
-
-
63549116796
-
Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival
-
J.E. Abraham, P. Harrington, K.E. Driver, J. Tyrer, D.F. Easton, and A.M. Dunning Common polymorphisms in the prostaglandin pathway genes and their association with breast cancer susceptibility and survival Clin Cancer Res 15 2009 2181 2191
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2181-2191
-
-
Abraham, J.E.1
Harrington, P.2
Driver, K.E.3
Tyrer, J.4
Easton, D.F.5
Dunning, A.M.6
-
176
-
-
0037447190
-
Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells
-
N.S. Cutler, R. Graves-Deal, B.J. LaFleur, Z. Gao, B.M. Boman, and R.H. Whitehead Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells Cancer Res 63 2003 1748 1751
-
(2003)
Cancer Res
, vol.63
, pp. 1748-1751
-
-
Cutler, N.S.1
Graves-Deal, R.2
Lafleur, B.J.3
Gao, Z.4
Boman, B.M.5
Whitehead, R.H.6
-
177
-
-
27744570398
-
Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy
-
J. Frigola, M. Muñoz, S.J. Clark, V. Moreno, G. Capella, and M.A. Peinado Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy Oncogene 24 2005 7320 7326
-
(2005)
Oncogene
, vol.24
, pp. 7320-7326
-
-
Frigola, J.1
Muñoz, M.2
Clark, S.J.3
Moreno, V.4
Capella, G.5
Peinado, M.A.6
-
178
-
-
34247157657
-
Genetic and epigenetic regulation of the human prostacyclin synthase promoter in lung cancer cell lines
-
R.S. Stearman, M.C. Grady, P. Nana-Sinkam, M. Varella-Garcia, and M.W. Geraci Genetic and epigenetic regulation of the human prostacyclin synthase promoter in lung cancer cell lines Mol Cancer Res 5 2007 295 308
-
(2007)
Mol Cancer Res
, vol.5
, pp. 295-308
-
-
Stearman, R.S.1
Grady, M.C.2
Nana-Sinkam, P.3
Varella-Garcia, M.4
Geraci, M.W.5
-
179
-
-
80555150822
-
Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer
-
M.C. Cathcart, S.G. Gray, A.M. Baird, E. Boyle, K. Gately, and E. Kay Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer Cancer 2011
-
(2011)
Cancer
-
-
Cathcart, M.C.1
Gray, S.G.2
Baird, A.M.3
Boyle, E.4
Gately, K.5
Kay, E.6
-
180
-
-
14544285134
-
Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2′-deoxycytidine
-
J. Chen, C. Röcken, L. Klein-Hitpass, T. Götze, A. Leodolter, and P. Malfertheiner Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2′-deoxycytidine Clin Exp Metastasis 21 2004 389 397
-
(2004)
Clin Exp Metastasis
, vol.21
, pp. 389-397
-
-
Chen, J.1
Röcken, C.2
Klein-Hitpass, L.3
Götze, T.4
Leodolter, A.5
Malfertheiner, P.6
-
181
-
-
0034700110
-
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer
-
R.A. Gupta, J. Tan, W.F. Krause, M.W. Geraci, T.M. Willson, and S.K. Dey Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer Proc Natl Acad Sci U S A 97 2000 13275 13280
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13275-13280
-
-
Gupta, R.A.1
Tan, J.2
Krause, W.F.3
Geraci, M.W.4
Willson, T.M.5
Dey, S.K.6
-
182
-
-
34447562564
-
IP receptor-dependent activation of PPARgamma by stable prostacyclin analogues
-
E. Falcetti, D.M. Flavell, B. Staels, A. Tinker, S.G. Haworth, and L.H. Clapp IP receptor-dependent activation of PPARgamma by stable prostacyclin analogues Biochem Biophys Res Commun 360 2007 821 827
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 821-827
-
-
Falcetti, E.1
Flavell, D.M.2
Staels, B.3
Tinker, A.4
Haworth, S.G.5
Clapp, L.H.6
-
183
-
-
43249130983
-
RNA interference against peroxisome proliferator-activated receptor delta gene promotes proliferation of human colorectal cancer cells
-
L. Yang, Z.-G. Zhou, X.-L. Zheng, L. Wang, Y.-Y. Yu, and B. Zhou RNA interference against peroxisome proliferator-activated receptor delta gene promotes proliferation of human colorectal cancer cells Dis Colon Rectum 51 2008 318 326
-
(2008)
Dis Colon Rectum
, vol.51
, pp. 318-326
-
-
Yang, L.1
Zhou, Z.-G.2
Zheng, X.-L.3
Wang, L.4
Yu, Y.-Y.5
Zhou, B.6
-
185
-
-
62849127105
-
PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer
-
M. Ghosh, Y. Ai, K. Narko, Z. Wang, J.M. Peters, and T. Hla PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer Prostaglandins Other Lipid Mediat 88 2009 97 100
-
(2009)
Prostaglandins Other Lipid Mediat
, vol.88
, pp. 97-100
-
-
Ghosh, M.1
Ai, Y.2
Narko, K.3
Wang, Z.4
Peters, J.M.5
Hla, T.6
-
186
-
-
62949100452
-
Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis
-
S. Ogino, K. Shima, Y. Baba, K. Nosho, N. Irahara, and S. Kure Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis Gastroenterology 136 2009 1242 1250
-
(2009)
Gastroenterology
, vol.136
, pp. 1242-1250
-
-
Ogino, S.1
Shima, K.2
Baba, Y.3
Nosho, K.4
Irahara, N.5
Kure, S.6
-
187
-
-
78649953952
-
Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome
-
M. Pancione, L. Sabatino, A. Fucci, V. Carafa, A. Nebbioso, and N. Forte Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome PLoS One 5 2010 e14229
-
(2010)
PLoS One
, vol.5
, pp. 14229
-
-
Pancione, M.1
Sabatino, L.2
Fucci, A.3
Carafa, V.4
Nebbioso, A.5
Forte, N.6
-
188
-
-
0033627825
-
Prostaglandin D synthase: Structure and function
-
Y. Urade, and O. Hayaishi Prostaglandin D synthase: structure and function Vitam Horm 58 2000 89 120
-
(2000)
Vitam Horm
, vol.58
, pp. 89-120
-
-
Urade, Y.1
Hayaishi, O.2
-
189
-
-
0036669560
-
Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence
-
Y. Urade, and N. Eguchi Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence Prostaglandins Other Lipid Mediat 68-69 2002 375 382
-
(2002)
Prostaglandins Other Lipid Mediat
, vol.68-69
, pp. 375-382
-
-
Urade, Y.1
Eguchi, N.2
-
190
-
-
0029925892
-
Diagnostic value of molecular forms of prostate-specific antigen for female breast cancer
-
D.N. Melegos, and E.P. Diamandis Diagnostic value of molecular forms of prostate-specific antigen for female breast cancer Clin Biochem 29 1996 193 200
-
(1996)
Clin Biochem
, vol.29
, pp. 193-200
-
-
Melegos, D.N.1
Diamandis, E.P.2
-
191
-
-
0031732296
-
Quantification of prostaglandin D synthetase in cerebrospinal fluid: A potential marker for brain tumor
-
L. Saso, M.G. Leone, C. Sorrentino, S. Giacomelli, B. Silvestrini, and J. Grima Quantification of prostaglandin D synthetase in cerebrospinal fluid: a potential marker for brain tumor Biochem Mol Biol Int 46 1998 643 656
-
(1998)
Biochem Mol Biol Int
, vol.46
, pp. 643-656
-
-
Saso, L.1
Leone, M.G.2
Sorrentino, C.3
Giacomelli, S.4
Silvestrini, B.5
Grima, J.6
-
192
-
-
0035667732
-
Expression of prostaglandin D synthase in ovarian cancer
-
B. Su, M. Guan, R. Zhao, and Y. Lu Expression of prostaglandin D synthase in ovarian cancer Clin Chem Lab Med 39 2001 1198 1203
-
(2001)
Clin Chem Lab Med
, vol.39
, pp. 1198-1203
-
-
Su, B.1
Guan, M.2
Zhao, R.3
Lu, Y.4
-
193
-
-
55749089731
-
Loss of prostaglandin D2 synthase: A key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma
-
C.A. Payne, S. Maleki, M. Messina, M.G. O'Sullivan, G. Stone, and N.R. Hall Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma Mol Cancer Ther 7 2008 3420 3428
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3420-3428
-
-
Payne, C.A.1
Maleki, S.2
Messina, M.3
O'Sullivan, M.G.4
Stone, G.5
Hall, N.R.6
-
194
-
-
77956188282
-
Diminished lipocalin-type prostaglandin D(2) synthase expression in human lung tumors
-
L. Ragolia, T. Palaia, C.E. Hall, J. Klein, and A. Büyük Diminished lipocalin-type prostaglandin D(2) synthase expression in human lung tumors Lung Cancer 70 2010 103 109
-
(2010)
Lung Cancer
, vol.70
, pp. 103-109
-
-
Ragolia, L.1
Palaia, T.2
Hall, C.E.3
Klein, J.4
Büyük, A.5
-
195
-
-
1942502821
-
Prostanoids and prostanoid receptors in signal transduction
-
C.L. Bos, D.J. Richel, T. Ritsema, M.P. Peppelenbosch, and H.H. Versteeg Prostanoids and prostanoid receptors in signal transduction Int J Biochem Cell Biol 36 2004 1187 1205
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1187-1205
-
-
Bos, C.L.1
Richel, D.J.2
Ritsema, T.3
Peppelenbosch, M.P.4
Versteeg, H.H.5
-
196
-
-
0035216234
-
Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP
-
F.G. Gervais, R.P. Cruz, A. Chateauneuf, S. Gale, N. Sawyer, and F. Nantel Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP J Allergy Clin Immunol 108 2001 982 988
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 982-988
-
-
Gervais, F.G.1
Cruz, R.P.2
Chateauneuf, A.3
Gale, S.4
Sawyer, N.5
Nantel, F.6
-
197
-
-
58149388214
-
Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo
-
T. Murata, M.I. Lin, K. Aritake, S. Matsumoto, S. Narumiya, and H. Ozaki Role of prostaglandin D2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivo Proc Natl Acad Sci U S A 105 2008 20009 20014
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 20009-20014
-
-
Murata, T.1
Lin, M.I.2
Aritake, K.3
Matsumoto, S.4
Narumiya, S.5
Ozaki, H.6
-
198
-
-
0035862329
-
Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
-
H. Hirai, K. Tanaka, O. Yoshie, K. Ogawa, K. Kenmotsu, and Y. Takamori Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2 J Exp Med 193 2001 255 261
-
(2001)
J Exp Med
, vol.193
, pp. 255-261
-
-
Hirai, H.1
Tanaka, K.2
Yoshie, O.3
Ogawa, K.4
Kenmotsu, K.5
Takamori, Y.6
-
199
-
-
35848967243
-
Prostanoid receptor expression in colorectal cancer related to tumor stage, differentiation and progression
-
A. Gustafsson, E. Hansson, U. Kressner, S. Nordgren, M. Andersson, and C. Lonnroth Prostanoid receptor expression in colorectal cancer related to tumor stage, differentiation and progression Acta Oncol 46 2007 1107 1112
-
(2007)
Acta Oncol
, vol.46
, pp. 1107-1112
-
-
Gustafsson, A.1
Hansson, E.2
Kressner, U.3
Nordgren, S.4
Andersson, M.5
Lonnroth, C.6
-
200
-
-
2542446266
-
Expression of prostaglandin D2 receptors DP1 and DP2 by human colorectal cancer cells
-
G. Hawcroft, S.H. Gardner, and M.A. Hull Expression of prostaglandin D2 receptors DP1 and DP2 by human colorectal cancer cells Cancer Lett 210 2004 81 84
-
(2004)
Cancer Lett
, vol.210
, pp. 81-84
-
-
Hawcroft, G.1
Gardner, S.H.2
Hull, M.A.3
-
201
-
-
50949113230
-
In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma
-
B. Sadikovic, M. Yoshimoto, K. Al-Romaih, G. Maire, M. Zielenska, and J.A. Squire In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma PLoS One 3 2008 e2834
-
(2008)
PLoS One
, vol.3
, pp. 2834
-
-
Sadikovic, B.1
Yoshimoto, M.2
Al-Romaih, K.3
Maire, G.4
Zielenska, M.5
Squire, J.A.6
-
202
-
-
13244260734
-
Role of COX-2, thromboxane A2 synthase, and prostaglandin I2 synthase in papillary thyroid carcinoma growth
-
S. Kajita, K.H. Ruebel, M.B. Casey, N. Nakamura, and R.V. Lloyd Role of COX-2, thromboxane A2 synthase, and prostaglandin I2 synthase in papillary thyroid carcinoma growth Mod Pathol 18 2005 221 227
-
(2005)
Mod Pathol
, vol.18
, pp. 221-227
-
-
Kajita, S.1
Ruebel, K.H.2
Casey, M.B.3
Nakamura, N.4
Lloyd, R.V.5
-
203
-
-
29244451423
-
Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer
-
O. Moussa, J.S. Yordy, H. Abol-Enein, D. Sinha, N.K. Bissada, and P.V. Halushka Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer Cancer Res 65 2005 11581 11587
-
(2005)
Cancer Res
, vol.65
, pp. 11581-11587
-
-
Moussa, O.1
Yordy, J.S.2
Abol-Enein, H.3
Sinha, D.4
Bissada, N.K.5
Halushka, P.V.6
-
204
-
-
33749239087
-
Activation of the thromboxane A2 pathway in human prostate cancer correlates with tumor Gleason score and pathologic stage
-
T. Dassesse, X. de Leval, L. de Leval, B. Pirotte, V. Castronovo, and D. Waltregny Activation of the thromboxane A2 pathway in human prostate cancer correlates with tumor Gleason score and pathologic stage Eur Urol 50 2006 1021 1031
-
(2006)
Eur Urol
, vol.50
, pp. 1021-1031
-
-
Dassesse, T.1
De Leval, X.2
De Leval, L.3
Pirotte, B.4
Castronovo, V.5
Waltregny, D.6
-
205
-
-
33646898794
-
Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A2
-
H. Sakai, T. Suzuki, Y. Takahashi, M. Ukai, K. Tauchi, and T. Fujii Upregulation of thromboxane synthase in human colorectal carcinoma and the cancer cell proliferation by thromboxane A2 FEBS Lett 580 2006 3368 3374
-
(2006)
FEBS Lett
, vol.580
, pp. 3368-3374
-
-
Sakai, H.1
Suzuki, T.2
Takahashi, Y.3
Ukai, M.4
Tauchi, K.5
Fujii, T.6
-
206
-
-
0029854898
-
Multiple factors regulating the expression of human thromboxane synthase gene
-
K.D. Lee, S.J. Baek, and R.F. Shen Multiple factors regulating the expression of human thromboxane synthase gene Biochem J 319 Pt 3 1996 783 791
-
(1996)
Biochem J
, vol.319
, Issue.PART 3
, pp. 783-791
-
-
Lee, K.D.1
Baek, S.J.2
Shen, R.F.3
-
207
-
-
27744513891
-
Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer
-
G. Watkins, A. Douglas-Jones, R.E. Mansel, and W.G. Jiang Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer Int Semin Surg Oncol 2 2005 23
-
(2005)
Int Semin Surg Oncol
, vol.2
, pp. 23
-
-
Watkins, G.1
Douglas-Jones, A.2
Mansel, R.E.3
Jiang, W.G.4
-
208
-
-
0041779528
-
Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases
-
M.F. Paz, S. Wei, J.C. Cigudosa, S. Rodriguez-Perales, M.A. Peinado, and T.H. Huang Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases Hum Mol Genet 12 2003 2209 2219
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2209-2219
-
-
Paz, M.F.1
Wei, S.2
Cigudosa, J.C.3
Rodriguez-Perales, S.4
Peinado, M.A.5
Huang, T.H.6
-
209
-
-
59449086542
-
Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7
-
Z. Kabututu, M. Manin, J.-C. Pointud, T. Maruyama, N. Nagata, and S. Lambert Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7 J Biochem (Tokyo) 145 2009 161 168
-
(2009)
J Biochem (Tokyo)
, vol.145
, pp. 161-168
-
-
Kabututu, Z.1
Manin, M.2
Pointud, J.-C.3
Maruyama, T.4
Nagata, N.5
Lambert, S.6
-
210
-
-
0038399036
-
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha)
-
D. Wölfle Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha) Toxicology 188 2003 139 147
-
(2003)
Toxicology
, vol.188
, pp. 139-147
-
-
Wölfle, D.1
-
211
-
-
34547121441
-
Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells
-
D. Qualtrough, A. Kaidi, S. Chell, H.N. Jabbour, A.C. Williams, and C. Paraskeva Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells Int J Cancer 121 2007 734 740
-
(2007)
Int J Cancer
, vol.121
, pp. 734-740
-
-
Qualtrough, D.1
Kaidi, A.2
Chell, S.3
Jabbour, H.N.4
Williams, A.C.5
Paraskeva, C.6
-
213
-
-
0026438060
-
Clinical significance of prostacyclin and thromboxane in cancer of the female breast and genital tract
-
S. Nigam, A. Zakrzewicz, S. Eskafi, and A. Roscher Clinical significance of prostacyclin and thromboxane in cancer of the female breast and genital tract Cancer Metastasis Rev 11 1992 411 420
-
(1992)
Cancer Metastasis Rev
, vol.11
, pp. 411-420
-
-
Nigam, S.1
Zakrzewicz, A.2
Eskafi, S.3
Roscher, A.4
-
214
-
-
78650910642
-
The human aldose reductase AKR1B1 qualifies as the primary prostaglandin F synthase in the endometrium
-
E. Bresson, S. Boucher-Kovalik, P. Chapdelaine, E. Madore, N. Harvey, and P.Y. Laberge The human aldose reductase AKR1B1 qualifies as the primary prostaglandin F synthase in the endometrium J Clin Endocrinol Metab 96 2011 210 219
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 210-219
-
-
Bresson, E.1
Boucher-Kovalik, S.2
Chapdelaine, P.3
Madore, E.4
Harvey, N.5
Laberge, P.Y.6
-
215
-
-
67349236706
-
Regulation of AKR1B1 by thyroid hormone and its receptors
-
C.-S. Liao, P.-J. Tai, Y.-H. Huang, R.-N. Chen, S.-M. Wu, and L.-W. Kuo Regulation of AKR1B1 by thyroid hormone and its receptors Mol Cell Endocrinol 307 2009 109 117
-
(2009)
Mol Cell Endocrinol
, vol.307
, pp. 109-117
-
-
Liao, C.-S.1
Tai, P.-J.2
Huang, Y.-H.3
Chen, R.-N.4
Wu, S.-M.5
Kuo, L.-W.6
-
216
-
-
2942668375
-
Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors
-
A.-M. Lefrançois-Martinez, J. Bertherat, P. Val, C. Tournaire, N. Gallo-Payet, and D. Hyndman Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors J Clin Endocrinol Metab 89 2004 3010 3019
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 3010-3019
-
-
Lefrançois-Martinez, A.-M.1
Bertherat, J.2
Val, P.3
Tournaire, C.4
Gallo-Payet, N.5
Hyndman, D.6
-
217
-
-
77955078547
-
Downregulation of AKR1B10 gene expression in colorectal cancer
-
E.S. Kropotova, R.A. Tychko, O.L. Zinov'eva, A.F. Zyrianova, S.L. Khankin, and V.L. Cherkes Downregulation of AKR1B10 gene expression in colorectal cancer Mol Biol (Mosk) 44 2010 243 250
-
(2010)
Mol Biol (Mosk)
, vol.44
, pp. 243-250
-
-
Kropotova, E.S.1
Tychko, R.A.2
Zinov'Eva, O.L.3
Zyrianova, A.F.4
Khankin, S.L.5
Cherkes, V.L.6
-
218
-
-
72049130544
-
Prostaglandin F(2alpha)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway
-
K.J. Sales, D. Maldonado-Pérez, V. Grant, R.D. Catalano, M.R. Wilson, and P. Brown Prostaglandin F(2alpha)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway Biochim Biophys Acta 1793 2009 1917 1928
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1917-1928
-
-
Sales, K.J.1
Maldonado-Pérez, D.2
Grant, V.3
Catalano, R.D.4
Wilson, M.R.5
Brown, P.6
-
219
-
-
31744433660
-
Evidence for an instructive mechanism of de novo methylation in cancer cells
-
I. Keshet, Y. Schlesinger, S. Farkash, E. Rand, M. Hecht, and E. Segal Evidence for an instructive mechanism of de novo methylation in cancer cells Nat Genet 38 2006 149 153
-
(2006)
Nat Genet
, vol.38
, pp. 149-153
-
-
Keshet, I.1
Schlesinger, Y.2
Farkash, S.3
Rand, E.4
Hecht, M.5
Segal, E.6
-
220
-
-
0035349741
-
Fine mapping of the PTGFR gene to 1p31 region and mutation analysis in human breast cancer
-
K. Sossey-Alaoui, E. Kitamura, and J.K. Cowell Fine mapping of the PTGFR gene to 1p31 region and mutation analysis in human breast cancer Int J Mol Med 7 2001 543 546
-
(2001)
Int J Mol Med
, vol.7
, pp. 543-546
-
-
Sossey-Alaoui, K.1
Kitamura, E.2
Cowell, J.K.3
-
222
-
-
2942571203
-
Polymorphisms in PTGS1 (=COX-1) and risk of colorectal polyps
-
C.M. Ulrich, J. Bigler, R. Sparks, J. Whitton, J.G. Sibert, and E.L. Goode Polymorphisms in PTGS1 (=COX-1) and risk of colorectal polyps Cancer Epidemiol Biomarkers Prev 13 2004 889 893
-
(2004)
Cancer Epidemiol Biomarkers Prev
, vol.13
, pp. 889-893
-
-
Ulrich, C.M.1
Bigler, J.2
Sparks, R.3
Whitton, J.4
Sibert, J.G.5
Goode, E.L.6
-
223
-
-
78249271390
-
Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk
-
B. Frank, M. Hoffmeister, N. Klopp, T. Illig, J. Chang-Claude, and H. Brenner Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk Int J Cancer 127 2010 2822 2830
-
(2010)
Int J Cancer
, vol.127
, pp. 2822-2830
-
-
Frank, B.1
Hoffmeister, M.2
Klopp, N.3
Illig, T.4
Chang-Claude, J.5
Brenner, H.6
-
224
-
-
56849112856
-
Low-penetrance alleles predisposing to sporadic colorectal cancers: A French case-controlled genetic association study
-
S. Küry, B. Buecher, S. Robiou-du-Pont, C. Scoul, H. Colman, and T. Le Neel Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study BMC Cancer 8 2008 326
-
(2008)
BMC Cancer
, vol.8
, pp. 326
-
-
Küry, S.1
Buecher, B.2
Robiou-Du-Pont, S.3
Scoul, C.4
Colman, H.5
Le Neel, T.6
-
225
-
-
33745630328
-
Prostaglandin-endoperoxide synthase 2 (PTGS2) gene polymorphisms and risk of biliary tract cancer and gallstones: A population-based study in Shanghai, China
-
L.C. Sakoda, Y.-T. Gao, B.E. Chen, J. Chen, P.S. Rosenberg, and A. Rashid Prostaglandin-endoperoxide synthase 2 (PTGS2) gene polymorphisms and risk of biliary tract cancer and gallstones: a population-based study in Shanghai, China Carcinogenesis 27 2006 1251 1256
-
(2006)
Carcinogenesis
, vol.27
, pp. 1251-1256
-
-
Sakoda, L.C.1
Gao, Y.-T.2
Chen, B.E.3
Chen, J.4
Rosenberg, P.S.5
Rashid, A.6
-
226
-
-
62749190612
-
A novel single nucleotide polymorphism of the cyclooxygenase-2 gene associated with breast cancer
-
F. Li, G.S. Ren, H.Y. Li, X.Y. Wang, L. Chen, and J. Li A novel single nucleotide polymorphism of the cyclooxygenase-2 gene associated with breast cancer Clin Oncol (R Coll Radiol) 21 2009 302 305
-
(2009)
Clin Oncol (R Coll Radiol)
, vol.21
, pp. 302-305
-
-
Li, F.1
Ren, G.S.2
Li, H.Y.3
Wang, X.Y.4
Chen, L.5
Li, J.6
-
227
-
-
78449274137
-
Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists
-
S. Schonfeld, P. Bhatti, E.E. Brown, M.S. Linet, S.L. Simon, and R.M. Weinstock Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists Cancer Causes Control 21 2010 1857 1866
-
(2010)
Cancer Causes Control
, vol.21
, pp. 1857-1866
-
-
Schonfeld, S.1
Bhatti, P.2
Brown, E.E.3
Linet, M.S.4
Simon, S.L.5
Weinstock, R.M.6
-
228
-
-
77950886696
-
PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: Results from the Breast and Prostate Cancer Cohort Consortium (BPC3)
-
L. Dossus, R. Kaaks, F. Canzian, D. Albanes, S.I. Berndt, and H. Boeing PTGS2 and IL6 genetic variation and risk of breast and prostate cancer: results from the Breast and Prostate Cancer Cohort Consortium (BPC3) Carcinogenesis 31 2010 455 461
-
(2010)
Carcinogenesis
, vol.31
, pp. 455-461
-
-
Dossus, L.1
Kaaks, R.2
Canzian, F.3
Albanes, D.4
Berndt, S.I.5
Boeing, H.6
-
229
-
-
33644758283
-
The cyclooxygenase-2 (PTGS2) 8473T>C polymorphism is associated with breast cancer risk
-
U. Langsenlehner, B. Yazdani-Biuki, T. Eder, W. Renner, T.C. Wascher, and B. Paulweber The cyclooxygenase-2 (PTGS2) 8473T>C polymorphism is associated with breast cancer risk Clin Cancer Res 12 2006 1392 1394
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1392-1394
-
-
Langsenlehner, U.1
Yazdani-Biuki, B.2
Eder, T.3
Renner, W.4
Wascher, T.C.5
Paulweber, B.6
-
230
-
-
42249092101
-
Profiling of genetic variations in inflammation pathway genes in relation to bladder cancer predisposition
-
H. Yang, J. Gu, X. Lin, H.B. Grossman, Y. Ye, and C.P. Dinney Profiling of genetic variations in inflammation pathway genes in relation to bladder cancer predisposition Clin Cancer Res 14 2008 2236 2244
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2236-2244
-
-
Yang, H.1
Gu, J.2
Lin, X.3
Grossman, H.B.4
Ye, Y.5
Dinney, C.P.6
-
231
-
-
33745192097
-
Polymorphisms in the genes involved in the arachidonic acid-pathway, fish consumption and the risk of colorectal cancer
-
C.L.E. Siezen, H.B. Bueno-de-Mesquita, P.H.M. Peeters, N.R. Kram, M. van Doeselaar, and H.J. van Kranen Polymorphisms in the genes involved in the arachidonic acid-pathway, fish consumption and the risk of colorectal cancer Int J Cancer 119 2006 297 303
-
(2006)
Int J Cancer
, vol.119
, pp. 297-303
-
-
Siezen, C.L.E.1
Bueno-De-Mesquita, H.B.2
Peeters, P.H.M.3
Kram, N.R.4
Van Doeselaar, M.5
Van Kranen, H.J.6
-
232
-
-
3843102713
-
Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer
-
D.G. Cox, C. Pontes, E. Guino, M. Navarro, A. Osorio, and F. Canzian Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer Br J Cancer 91 2004 339 343
-
(2004)
Br J Cancer
, vol.91
, pp. 339-343
-
-
Cox, D.G.1
Pontes, C.2
Guino, E.3
Navarro, M.4
Osorio, A.5
Canzian, F.6
-
233
-
-
34547166662
-
Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer
-
T. Kawasaki, K. Nosho, M. Ohnishi, Y. Suemoto, G.J. Kirkner, and R. Dehari Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer Neoplasia 9 2007 569 577
-
(2007)
Neoplasia
, vol.9
, pp. 569-577
-
-
Kawasaki, T.1
Nosho, K.2
Ohnishi, M.3
Suemoto, Y.4
Kirkner, G.J.5
Dehari, R.6
-
234
-
-
58149340659
-
Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer
-
S. Ogino, G.J. Kirkner, K. Nosho, N. Irahara, S. Kure, and K. Shima Cyclooxygenase-2 expression is an independent predictor of poor prognosis in colon cancer Clin Cancer Res 14 2008 8221 8227
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8221-8227
-
-
Ogino, S.1
Kirkner, G.J.2
Nosho, K.3
Irahara, N.4
Kure, S.5
Shima, K.6
-
235
-
-
79251616587
-
Gallbladder cancer predisposition: A multigenic approach to DNA-repair, apoptotic and inflammatory pathway genes
-
K. Srivastava, A. Srivastava, A. Kumar, and B. Mittal Gallbladder cancer predisposition: a multigenic approach to DNA-repair, apoptotic and inflammatory pathway genes PLoS One 6 2011 e16449
-
(2011)
PLoS One
, vol.6
, pp. 16449
-
-
Srivastava, K.1
Srivastava, A.2
Kumar, A.3
Mittal, B.4
-
236
-
-
68149152902
-
Functional polymorphisms of the cyclooxygenase (PTGS2) gene and risk for gallbladder cancer in a North Indian population
-
K. Srivastava, A. Srivastava, S.N. Pandey, A. Kumar, and B. Mittal Functional polymorphisms of the cyclooxygenase (PTGS2) gene and risk for gallbladder cancer in a North Indian population J Gastroenterol 44 2009 774 780
-
(2009)
J Gastroenterol
, vol.44
, pp. 774-780
-
-
Srivastava, K.1
Srivastava, A.2
Pandey, S.N.3
Kumar, A.4
Mittal, B.5
-
237
-
-
79551517315
-
A new cyclo-oxygenase-2 gene variant in the Han Chinese population is associated with an increased risk of gastric carcinoma
-
Y. Li, W. He, T. Liu, and Q. Zhang A new cyclo-oxygenase-2 gene variant in the Han Chinese population is associated with an increased risk of gastric carcinoma Mol Diag Ther 14 2010 351 355
-
(2010)
Mol Diag Ther
, vol.14
, pp. 351-355
-
-
Li, Y.1
He, W.2
Liu, T.3
Zhang, Q.4
-
238
-
-
0141534249
-
Aberrant methylation of the specific CpG island portion regulates cyclooxygenase-2 gene expression in human gastric carcinomas
-
K. Hur, S.H. Song, H.S. Lee, W. Ho Kim, Y.-J. Bang, and H.-K. Yang Aberrant methylation of the specific CpG island portion regulates cyclooxygenase-2 gene expression in human gastric carcinomas Biochem Biophys Res Commun 310 2003 844 851
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 844-851
-
-
Hur, K.1
Song, S.H.2
Lee, H.S.3
Ho Kim, W.4
Bang, Y.-J.5
Yang, H.-K.6
-
239
-
-
33751201559
-
Infrequent COX-2 expression due to promoter hypermethylation in gastric cancers in Dalian
-
L. Huang, K.-L. Zhang, H. Li, X.-Y. Chen, Q.-Y. Kong, and Y. Sun Infrequent COX-2 expression due to promoter hypermethylation in gastric cancers in Dalian China. Hum Pathol 37 2006 1557 1567
-
(2006)
China. Hum Pathol
, vol.37
, pp. 1557-1567
-
-
Huang, L.1
Zhang, K.-L.2
Li, H.3
Chen, X.-Y.4
Kong, Q.-Y.5
Sun, Y.6
-
240
-
-
77953400487
-
Gastric carcinoma and chronic gastritis: Epigenetic regulation of CDH1 (E-Cadherin), CDKN2A (p16INK4A), PTGS2 (COX-2) and EGFR genes through methylation
-
M. Silva, D. Azenha, C. Pereira, A. Almeida, S. Balseiro, and A.M. Sampaio Gastric carcinoma and chronic gastritis: epigenetic regulation of CDH1 (E-Cadherin), CDKN2A (p16INK4A), PTGS2 (COX-2) and EGFR genes through methylation Acta Med Port 23 2010 5 14
-
(2010)
Acta Med Port
, vol.23
, pp. 5-14
-
-
Silva, M.1
Azenha, D.2
Pereira, C.3
Almeida, A.4
Balseiro, S.5
Sampaio, A.M.6
-
241
-
-
22144460173
-
Mechanism and clinical significance of cyclooxygenase-2 expression in gastric cancer
-
B.-C. Wang, C.-Q. Guo, C. Sun, Q.-L. Sun, G.-Y. Liu, and D.-G. Li Mechanism and clinical significance of cyclooxygenase-2 expression in gastric cancer World J Gastroenterol 11 2005 3240 3244
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3240-3244
-
-
Wang, B.-C.1
Guo, C.-Q.2
Sun, C.3
Sun, Q.-L.4
Liu, G.-Y.5
Li, D.-G.6
-
242
-
-
77954711621
-
Genetic variants in inflammation pathway genes and asthma in glioma susceptibility
-
E. Amirian, Y. Liu, M.E. Scheurer, R. El-Zein, M.R. Gilbert, and M.L. Bondy Genetic variants in inflammation pathway genes and asthma in glioma susceptibility Neuro-oncology 12 2010 444 452
-
(2010)
Neuro-oncology
, vol.12
, pp. 444-452
-
-
Amirian, E.1
Liu, Y.2
Scheurer, M.E.3
El-Zein, R.4
Gilbert, M.R.5
Bondy, M.L.6
-
243
-
-
1242307933
-
Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer
-
D. Campa, S. Zienolddiny, V. Maggini, V. Skaug, A. Haugen, and F. Canzian Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer Carcinogenesis 25 2004 229 235
-
(2004)
Carcinogenesis
, vol.25
, pp. 229-235
-
-
Campa, D.1
Zienolddiny, S.2
Maggini, V.3
Skaug, V.4
Haugen, A.5
Canzian, F.6
-
244
-
-
56649108188
-
PTGS2 (COX-2) -765 G > C functional promoter polymorphism and its association with risk and lymph node metastasis in nasopharyngeal carcinoma
-
H. Ben Nasr, K. Chahed, N. Bouaouina, and L. Chouchane PTGS2 (COX-2) -765 G > C functional promoter polymorphism and its association with risk and lymph node metastasis in nasopharyngeal carcinoma Mol Biol Rep 36 2009 193 200
-
(2009)
Mol Biol Rep
, vol.36
, pp. 193-200
-
-
Ben Nasr, H.1
Chahed, K.2
Bouaouina, N.3
Chouchane, L.4
-
245
-
-
34250686952
-
Association of functional gene variants in the regulatory regions of COX-2 gene (PTGS2) with nonmelanoma skin cancer after organ transplantation
-
M.G. Lira, S. Mazzola, G. Tessari, G. Malerba, M. Ortombina, and L. Naldi Association of functional gene variants in the regulatory regions of COX-2 gene (PTGS2) with nonmelanoma skin cancer after organ transplantation Br J Dermatol 157 2007 49 57
-
(2007)
Br J Dermatol
, vol.157
, pp. 49-57
-
-
Lira, M.G.1
Mazzola, S.2
Tessari, G.3
Malerba, G.4
Ortombina, M.5
Naldi, L.6
-
246
-
-
77956976649
-
Pooled analysis of the association of PTGS2 rs5275 polymorphism and NSAID use with invasive ovarian carcinoma risk
-
G. Lurie, K.L. Terry, L.R. Wilkens, P.J. Thompson, K.E. McDuffie, and M.E. Carney Pooled analysis of the association of PTGS2 rs5275 polymorphism and NSAID use with invasive ovarian carcinoma risk Cancer Causes Control 21 2010 1731 1741
-
(2010)
Cancer Causes Control
, vol.21
, pp. 1731-1741
-
-
Lurie, G.1
Terry, K.L.2
Wilkens, L.R.3
Thompson, P.J.4
McDuffie, K.E.5
Carney, M.E.6
-
247
-
-
70350398901
-
Identification of candidate epigenetic biomarkers for ovarian cancer detection
-
Y.-W. Huang, R.A. Jansen, E. Fabbri, D. Potter, S. Liyanarachchi, and M.W.Y. Chan Identification of candidate epigenetic biomarkers for ovarian cancer detection Oncol Rep 22 2009 853 861
-
(2009)
Oncol Rep
, vol.22
, pp. 853-861
-
-
Huang, Y.-W.1
Jansen, R.A.2
Fabbri, E.3
Potter, D.4
Liyanarachchi, S.5
Chan, M.W.Y.6
-
248
-
-
78149329845
-
Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice
-
S.K. Huang, A.S. Fisher, A.M. Scruggs, E.S. White, C.M. Hogaboam, and B.C. Richardson Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice Am J Pathol 2010
-
(2010)
Am J Pathol
-
-
Huang, S.K.1
Fisher, A.S.2
Scruggs, A.M.3
White, E.S.4
Hogaboam, C.M.5
Richardson, B.C.6
-
249
-
-
77950886948
-
Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk
-
B. Hoeft, J. Linseisen, L. Beckmann, K. Müller-Decker, F. Canzian, and A. Hüsing Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk Carcinogenesis 31 2010 466 472
-
(2010)
Carcinogenesis
, vol.31
, pp. 466-472
-
-
Hoeft, B.1
Linseisen, J.2
Beckmann, L.3
Müller-Decker, K.4
Canzian, F.5
Hüsing, A.6
|