메뉴 건너뛰기




Volumn 137, Issue 12, 1996, Pages 5739-5742

Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ESTROGEN; ESTROGEN RECEPTOR; PROSTAGLANDIN E2; PROTEIN KINASE C;

EID: 0030444771     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.12.8940410     Document Type: Article
Times cited : (404)

References (24)
  • 2
    • 0027261356 scopus 로고
    • Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue
    • Mahendroo MS, Mendelson CR, Simpson ER 1993 Tissue-specific and hormonally-controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue. J Biol Chem 268:19463-19470
    • (1993) J Biol Chem , vol.268 , pp. 19463-19470
    • Mahendroo, M.S.1    Mendelson, C.R.2    Simpson, E.R.3
  • 3
    • 0025914639 scopus 로고
    • arom: The promoter responsible for expression in adipose is different from that utilized in placenta
    • arom: the promoter responsible for expression in adipose is different from that utilized in placenta. J Biol Chem 266:11276-11281
    • (1991) J Biol Chem , vol.266 , pp. 11276-11281
    • Mahendroo, M.S.1    Means, G.D.2    Mendelson, C.R.3    Simpson, E.R.4
  • 4
    • 0026396006 scopus 로고
    • Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues
    • Means GD, Kilgore MW, Mahendroo MS, Mendelson CR, Simpson ER 1991 Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues. Mol Endocrinol 5:2005-2013
    • (1991) Mol Endocrinol , vol.5 , pp. 2005-2013
    • Means, G.D.1    Kilgore, M.W.2    Mahendroo, M.S.3    Mendelson, C.R.4    Simpson, E.R.5
  • 5
    • 0023831082 scopus 로고
    • Aromatase activity in adipose tissue from breast quadrants: A link with tumor site
    • O'Neill JS, Elton RA, Miller WR 1988 Aromatase activity in adipose tissue from breast quadrants: a link with tumor site. Brit Med J 296:741-743
    • (1988) Brit Med J , vol.296 , pp. 741-743
    • O'Neill, J.S.1    Elton, R.A.2    Miller, W.R.3
  • 6
    • 0027131199 scopus 로고
    • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
    • Bulun SE, Price TM, Mahendroo MS, Aitken J, Simpson ER 1993 A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. J Clin Endocrinol Metab 77:1622-1628
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1622-1628
    • Bulun, S.E.1    Price, T.M.2    Mahendroo, M.S.3    Aitken, J.4    Simpson, E.R.5
  • 8
    • 0029820178 scopus 로고    scopus 로고
    • Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients
    • in press
    • Agarwal VR, Bulun SE, Leitch M, Rohrich R, Simpson ER 1996 Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients. J Clin Endo Metab in press:
    • (1996) J Clin Endo Metab
    • Agarwal, V.R.1    Bulun, S.E.2    Leitch, M.3    Rohrich, R.4    Simpson, E.R.5
  • 9
    • 0022527481 scopus 로고
    • Growth factors suppress, and phorbol esters potentiate the action of dibutyryl cyclic AMP to stimulate aromatase activity of human adipose stromal cells
    • Mendelson CR, Corbin CJ, Smith ME, Smith J, Simpson ER 1986 Growth factors suppress, and phorbol esters potentiate the action of dibutyryl cyclic AMP to stimulate aromatase activity of human adipose stromal cells. Endocrinology 118:968-973
    • (1986) Endocrinology , vol.118 , pp. 968-973
    • Mendelson, C.R.1    Corbin, C.J.2    Smith, M.E.3    Smith, J.4    Simpson, E.R.5
  • 10
    • 0029013505 scopus 로고
    • Ad4BP/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary
    • Michael MD, Kilgore MW, Morohashi K-I, Simpson ER 1994 Ad4BP/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary. J Biol Chem 270:13561-13466
    • (1994) J Biol Chem , vol.270 , pp. 13561-113466
    • Michael, M.D.1    Kilgore, M.W.2    Morohashi, K.-I.3    Simpson, E.R.4
  • 11
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ 1979 Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 12
    • 0029616317 scopus 로고
    • Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR
    • Agarwal VR, Bulun SE, Simpson ER 1995 Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR. Mol Cell Probes 9:453-464
    • (1995) Mol Cell Probes , vol.9 , pp. 453-464
    • Agarwal, V.R.1    Bulun, S.E.2    Simpson, E.R.3
  • 13
    • 0019850380 scopus 로고
    • Potentiation of epinephrine-induced lipolysis by catechol estrogens and their methoxy derivatives
    • Ackerman GE, MacDonald PC, Gudelsky G, Mendelson CR, Simpson ER 1981 Potentiation of epinephrine-induced lipolysis by catechol estrogens and their methoxy derivatives. Endocrinology 109:2084-2088
    • (1981) Endocrinology , vol.109 , pp. 2084-2088
    • Ackerman, G.E.1    MacDonald, P.C.2    Gudelsky, G.3    Mendelson, C.R.4    Simpson, E.R.5
  • 14
    • 0021261088 scopus 로고
    • Regulation of aromatase activity of cultured adipose stromal cells by catecholamines and adrenocorticotropin
    • Mendelson CR, Smith ME, Cleland WH, Simpson ER 1984 Regulation of aromatase activity of cultured adipose stromal cells by catecholamines and adrenocorticotropin. Mol Cell Endocrinol 37:61-72
    • (1984) Mol Cell Endocrinol , vol.37 , pp. 61-72
    • Mendelson, C.R.1    Smith, M.E.2    Cleland, W.H.3    Simpson, E.R.4
  • 15
    • 0029586705 scopus 로고
    • Molecular regulation of prostaglandin biosynthesis
    • Robertson RP 1995 Molecular regulation of prostaglandin biosynthesis. TEM 6:293-297
    • (1995) TEM , vol.6 , pp. 293-297
    • Robertson, R.P.1
  • 16
    • 0016434895 scopus 로고
    • Biological activities of 17-phenyl-18, 19, 20-trinor prostaglandins
    • Miller WL, Weeks JR, Lauderdale JW 1975 Biological activities of 17-phenyl-18, 19, 20-trinor prostaglandins. Prostaglandins 9:9-18
    • (1975) Prostaglandins , vol.9 , pp. 9-18
    • Miller, W.L.1    Weeks, J.R.2    Lauderdale, J.W.3
  • 17
    • 0016267752 scopus 로고
    • Inhibition of gastric acid secretion and ulcer formation in the rat by orally-administered 11-deoxy-prostaglandin analogues: 15-hydroxy-16, 16-dimelhyl-9-oxoprost-5, 13-dienoric acids
    • Lippmann W 1974 Inhibition of gastric acid secretion and ulcer formation in the rat by orally-administered 11-deoxy-prostaglandin analogues: 15-hydroxy-16, 16-dimelhyl-9-oxoprost-5, 13-dienoric acids. Prostaglandins 7:231-246
    • (1974) Prostaglandins , vol.7 , pp. 231-246
    • Lippmann, W.1
  • 19
    • 0023189829 scopus 로고
    • Regulation of estrogen biosynthesis in human adipose stromal cells: Effects of dibutyryl cyclic AMP, epidermal growth factor, and phorbol esters on the synthesis of aromatase cytochrome P-450
    • Evans CT, Corbin CJ, Saunders CT, Merrill JC, Simpson ER, Mendelson CR 1987 Regulation of estrogen biosynthesis in human adipose stromal cells: effects of dibutyryl cyclic AMP, epidermal growth factor, and phorbol esters on the synthesis of aromatase cytochrome P-450. J Biol Chem 262:6914-6920
    • (1987) J Biol Chem , vol.262 , pp. 6914-6920
    • Evans, C.T.1    Corbin, C.J.2    Saunders, C.T.3    Merrill, J.C.4    Simpson, E.R.5    Mendelson, C.R.6
  • 20
    • 0018868971 scopus 로고
    • Suggesting that as elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells
    • Rolland PH, Martin PM, Jacquemier J, Rolland A, Toga M 1980 Suggesting that as elevated prostaglandin production is a marker of high metastatic potential for neoplastic cells. J Natl Cancer Inst 64:1061-1070
    • (1980) J Natl Cancer Inst , vol.64 , pp. 1061-1070
    • Rolland, P.H.1    Martin, P.M.2    Jacquemier, J.3    Rolland, A.4    Toga, M.5
  • 21
    • 0029416919 scopus 로고
    • 2 production and metabolism in human breast cancer cells and breast fibroblasts. Regulation by inflammatory mediators
    • 2 production and metabolism in human breast cancer cells and breast fibroblasts. Regulation by inflammatory mediators. Br J Cancer 72:1412-1419
    • (1995) Br J Cancer , vol.72 , pp. 1412-1419
    • Schrey, M.P.1    Patel, K.V.2
  • 23
    • 0019449973 scopus 로고
    • Neutral fats and cancer
    • Carroll KK 1981 Neutral fats and cancer. Cancer Res 41:3695-3699
    • (1981) Cancer Res , vol.41 , pp. 3695-3699
    • Carroll, K.K.1
  • 24
    • 0030025365 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and breast cancer
    • Harris RE, Nauboodim KK, Farrar WB 1996 Nonsteroidal anti-inflammatory drugs and breast cancer. Epidemiology 1:203-205
    • (1996) Epidemiology , vol.1 , pp. 203-205
    • Harris, R.E.1    Nauboodim, K.K.2    Farrar, W.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.