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Volumn 1, Issue 6, 1999, Pages 508-517

Synergistic Induction of Cyclooxygenase-2 by Transforming Growth Factor-β1 and Epidermal Growth Factor Inhibits Apoptosis in Epithelial Cells

Author keywords

Apoptosis; COX 2; EGF; TGF

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR; ISOENZYME; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033290356     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.neo.7900051     Document Type: Article
Times cited : (79)

References (65)
  • 3
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, and DuBois RN (1995). Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83, 493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 4
    • 0029975669 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthases-1 and -2
    • Smith WL, and Dewitt DL (1996). Prostaglandin endoperoxide H synthases-1 and -2. Adv Immunol 62, 167-215.
    • (1996) Adv Immunol , vol.62 , pp. 167-215
    • Smith, W.L.1    Dewitt, D.L.2
  • 5
    • 0026761738 scopus 로고
    • Aspirin and the potential role of prostaglandins in colon cancer
    • Marnett LJ (1992). Aspirin and the potential role of prostaglandins in colon cancer. Cancer Res 52, 5575-5589.
    • (1992) Cancer Res , vol.52 , pp. 5575-5589
    • Marnett, L.J.1
  • 6
    • 0024818522 scopus 로고
    • Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme
    • Yokoyama C, and Tanabe T (1989). Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Biochem Biophysics Res Commun 165, 888-894.
    • (1989) Biochem Biophysics Res Commun , vol.165 , pp. 888-894
    • Yokoyama, C.1    Tanabe, T.2
  • 7
    • 0026702494 scopus 로고
    • Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase
    • Fletcher BS, Kujubu DA, Perrin DM, and Hershman HR (1992). Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J Biol Chem 267, 4338-4344.
    • (1992) J Biol Chem , vol.267 , pp. 4338-4344
    • Fletcher, B.S.1    Kujubu, D.A.2    Perrin, D.M.3    Hershman, H.R.4
  • 8
    • 0027468941 scopus 로고
    • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
    • Jones DA, Carlton D, McIntyre MT, Zimmerman GA, and Prescott SM (1993). Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 268, 9049-9054.
    • (1993) J Biol Chem , vol.268 , pp. 9049-9054
    • Jones, D.A.1    Carlton, D.2    McIntyre, M.T.3    Zimmerman, G.A.4    Prescott, S.M.5
  • 9
    • 0029924110 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide synthase: Why two isoforms?
    • Williams CS, and DuBois RN (1996). Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 270, G393-G400.
    • (1996) Am J Physiol , vol.270
    • Williams, C.S.1    DuBois, R.N.2
  • 10
    • 0027293391 scopus 로고
    • Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
    • O'Neill GP, and Ford-Hutchinson AW (1993). Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues. FEBS Lett 330, 379-384.
    • (1993) FEBS Lett , vol.330 , pp. 379-384
    • O'Neill, G.P.1    Ford-Hutchinson, A.W.2
  • 12
    • 0032006784 scopus 로고    scopus 로고
    • Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
    • Kawamori T, Rao CV, Seibert K, and Reddy BS (1998). Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res 58, 409-412.
    • (1998) Cancer Res , vol.58 , pp. 409-412
    • Kawamori, T.1    Rao, C.V.2    Seibert, K.3    Reddy, B.S.4
  • 13
    • 0029794742 scopus 로고    scopus 로고
    • Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis
    • Reddy BS, Rao CV, and Seibert K (1996). Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis. Cancer Res 56, 4566-4569.
    • (1996) Cancer Res , vol.56 , pp. 4566-4569
    • Reddy, B.S.1    Rao, C.V.2    Seibert, K.3
  • 16
    • 0029008617 scopus 로고
    • Expression of prostaglandin G/H synthase-1 and-2 in human colorectal cancer
    • Kargman S, O'Neill G, Vickers P, Evans J, Mancini J, and Jothy S (1995). Expression of prostaglandin G/H synthase-1 and-2 in human colorectal cancer. Cancer Res 55, 2556-2559.
    • (1995) Cancer Res , vol.55 , pp. 2556-2559
    • Kargman, S.1    O'Neill, G.2    Vickers, P.3    Evans, J.4    Mancini, J.5    Jothy, S.6
  • 19
    • 0030817945 scopus 로고    scopus 로고
    • Dietary fat and colon cancer: Modulation of cyclooxygenase-2 by types and amount of dietary fat during the post-initiation stage of colon carcinogenesis
    • Singh J, Hamid R, and Reddy BS (1997). Dietary fat and colon cancer: modulation of cyclooxygenase-2 by types and amount of dietary fat during the post-initiation stage of colon carcinogenesis. Cancer Res 57, 3465-70.
    • (1997) Cancer Res , vol.57 , pp. 3465-3470
    • Singh, J.1    Hamid, R.2    Reddy, B.S.3
  • 21
    • 0030952695 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
    • Tsujii M, Kawano S, and DuBois RN (1997). Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 94, 3336-3340.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3336-3340
    • Tsujii, M.1    Kawano, S.2    DuBois, R.N.3
  • 22
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, and DuBois RN (1998). Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93, 705-716.
    • (1998) Cell , vol.93 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    DuBois, R.N.6
  • 25
    • 0028344102 scopus 로고
    • Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-α and phorbol ester
    • DuBois RN, Awad J, Morrow J, Roberts LJ, and Bishop PR (1994). Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-α and phorbol ester. J Clin Invest 93, 493-498.
    • (1994) J Clin Invest , vol.93 , pp. 493-498
    • DuBois, R.N.1    Awad, J.2    Morrow, J.3    Roberts, L.J.4    Bishop, P.R.5
  • 27
    • 0031845089 scopus 로고    scopus 로고
    • Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts
    • Diaz A, Chepenik KP, Korn JH, Reginato AM, and Jimenez SA (1998). Differential regulation of cyclooxygenases 1 and 2 by interleukin-1 beta, tumor necrosis factor-alpha, and transforming growth factor-beta 1 in human lung fibroblasts. Exp Cell Res 241, 222-229.
    • (1998) Exp Cell Res , vol.241 , pp. 222-229
    • Diaz, A.1    Chepenik, K.P.2    Korn, J.H.3    Reginato, A.M.4    Jimenez, S.A.5
  • 28
    • 14444267770 scopus 로고    scopus 로고
    • Non-small cell lung cancer cyclooxygenase activity and proliferation are inhibited by non-steroidal anti-inflammatory drugs
    • Hida T, Leyton J, Makheja AN, Ben-Av P, and Hla T (1998). Non-small cell lung cancer cyclooxygenase activity and proliferation are inhibited by non-steroidal anti-inflammatory drugs. Anticancer Res 18, 775-782.
    • (1998) Anticancer Res , vol.18 , pp. 775-782
    • Hida, T.1    Leyton, J.2    Makheja, A.N.3    Ben-Av, P.4    Hla, T.5
  • 30
    • 0030967310 scopus 로고    scopus 로고
    • Cyclooxygenase-2 induction and transforming growth factor beta growth inhibition in rat intestinal epithelial cells
    • Sheng H, Shao J, Hooton EB, Tsujii M, DuBois RN, and Beauchamp RD (1997). Cyclooxygenase-2 induction and transforming growth factor beta growth inhibition in rat intestinal epithelial cells. Cell Growth Differ 8, 463-470.
    • (1997) Cell Growth Differ , vol.8 , pp. 463-470
    • Sheng, H.1    Shao, J.2    Hooton, E.B.3    Tsujii, M.4    DuBois, R.N.5    Beauchamp, R.D.6
  • 31
    • 0028619845 scopus 로고
    • TGF-β1 augments expression of the TIS10/prostaglandin synthase-2 gene in intestinal epithelial cells
    • Gilbert RS, Reddy ST, Targan S, and Harschman HR (1994). TGF-β1 augments expression of the TIS10/prostaglandin synthase-2 gene in intestinal epithelial cells. Cell Mol Biol Res 40, 653-660.
    • (1994) Cell Mol Biol Res , vol.40 , pp. 653-660
    • Gilbert, R.S.1    Reddy, S.T.2    Targan, S.3    Harschman, H.R.4
  • 32
    • 0028145016 scopus 로고
    • Transforming growth factor beta 1 augments mitogen-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene both in Swiss 3T3 cells and in murine embryo fibroblasts
    • Gilbert RS, Reddy ST, Kujubu DA, Xie W, Luner S, and Herschman HR (1994). Transforming growth factor beta 1 augments mitogen-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene both in Swiss 3T3 cells and in murine embryo fibroblasts. J Cell Physiol 159, 67-75.
    • (1994) J Cell Physiol , vol.159 , pp. 67-75
    • Gilbert, R.S.1    Reddy, S.T.2    Kujubu, D.A.3    Xie, W.4    Luner, S.5    Herschman, H.R.6
  • 33
    • 0024436727 scopus 로고
    • Transforming growth factor-beta inhibits prostaglandin production in amnion and A431 cells
    • Berchuck A, MacDonald PC, Milewich L, and Casey ML (1989). Transforming growth factor-beta inhibits prostaglandin production in amnion and A431 cells. Prostaglandins 38, 453-464.
    • (1989) Prostaglandins , vol.38 , pp. 453-464
    • Berchuck, A.1    MacDonald, P.C.2    Milewich, L.3    Casey, M.L.4
  • 34
    • 0027980201 scopus 로고
    • TGF-beta 1 inhibits both endotoxin-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene in murine macrophages
    • Reddy ST, Gilbert RS, Xie W, Luner S, and Herschman HR (1994). TGF-beta 1 inhibits both endotoxin-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene in murine macrophages. J Leukocyte Biol 55, 192-200.
    • (1994) J Leukocyte Biol , vol.55 , pp. 192-200
    • Reddy, S.T.1    Gilbert, R.S.2    Xie, W.3    Luner, S.4    Herschman, H.R.5
  • 35
    • 0028785005 scopus 로고
    • v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcriptional factor
    • Xie W, and Herschman HR (1995). v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcriptional factor. J Biol Chem 270, 27622-27628.
    • (1995) J Biol Chem , vol.270 , pp. 27622-27628
    • Xie, W.1    Herschman, H.R.2
  • 36
    • 0029950418 scopus 로고    scopus 로고
    • Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum
    • Xie W, and Herschman HR (1996). Transcriptional regulation of prostaglandin synthase 2 gene expression by platelet-derived growth factor and serum. J Biol Chem 271, 31742-31748.
    • (1996) J Biol Chem , vol.271 , pp. 31742-31748
    • Xie, W.1    Herschman, H.R.2
  • 37
    • 0032557678 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 by the activated MEKK1/SEK1/ MKK4 p38 mitogen-activated protein kinase pathway
    • Guan Z, Buckman SY, Pentland AP, Templeton DJ, and Morrison AR (1998). Induction of cyclooxygenase-2 by the activated MEKK1/SEK1/ MKK4 p38 mitogen-activated protein kinase pathway. J Biol Chem 273, 12901-12908.
    • (1998) J Biol Chem , vol.273 , pp. 12901-12908
    • Guan, Z.1    Buckman, S.Y.2    Pentland, A.P.3    Templeton, D.J.4    Morrison, A.R.5
  • 38
    • 15444339428 scopus 로고    scopus 로고
    • Ceramide regulates the transcription of cyclooxygenase-2
    • Subbaramaiah K, Chung WJ, and Danenberg AL (1998). Ceramide regulates the transcription of cyclooxygenase-2. J Biol Chem 273, 32943-32949.
    • (1998) J Biol Chem , vol.273 , pp. 32943-32949
    • Subbaramaiah, K.1    Chung, W.J.2    Danenberg, A.L.3
  • 39
    • 0032555484 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 by activated Ha-Ras oncogene in rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
    • Sheng HM, Williums CS, Shao J, Peng L, DuBois RN, and Beauchamp RD (1998). Induction of cyclooxygenase-2 by activated Ha-Ras oncogene in rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J Biol Chem 273, 22120-22127.
    • (1998) J Biol Chem , vol.273 , pp. 22120-22127
    • Sheng, H.M.1    Williums, C.S.2    Shao, J.3    Peng, L.4    DuBois, R.N.5    Beauchamp, R.D.6
  • 40
    • 0033106484 scopus 로고    scopus 로고
    • A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
    • Kretzschmar M, Doody J, Timokhina I, and Massague J (1999). A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev 13, 804-816.
    • (1999) Genes Dev , vol.13 , pp. 804-816
    • Kretzschmar, M.1    Doody, J.2    Timokhina, I.3    Massague, J.4
  • 41
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of intemucleosomal fragmentation
    • Oberhammer F, Wilson LW, Dive C, Morris ID, Hickman JA, Wakeling AE, Walker PR, and Sikorska M (1993). Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of intemucleosomal fragmentation. EMBO J 12 (9), 3679-84.
    • (1993) EMBO J , vol.12 , Issue.9 , pp. 3679-3684
    • Oberhammer, F.1    Wilson, L.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.5    Wakeling, A.E.6    Walker, P.R.7    Sikorska, M.8
  • 45
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Levitzki A, and Gazit A (1995). Tyrosine kinase inhibition: an approach to drug development. Science 267, 1782-1788.
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 47
    • 0023279727 scopus 로고
    • Synergistic stimulation of fibroblast prostaglandin production by recombinant interleukin 1 and tumor necrosis factor
    • Elias JA, Gustilo K, Baeder W, and Freundlich B (1987). Synergistic stimulation of fibroblast prostaglandin production by recombinant interleukin 1 and tumor necrosis factor. J Immunol 135, 3812-3816.
    • (1987) J Immunol , vol.135 , pp. 3812-3816
    • Elias, J.A.1    Gustilo, K.2    Baeder, W.3    Freundlich, B.4
  • 48
    • 0024474185 scopus 로고
    • 2 production is synergistically increased in cultured human glomerular mesangial cells by combinations of IL-1 and tumor necrosis factor-alpha-1
    • 2 production is synergistically increased in cultured human glomerular mesangial cells by combinations of IL-1 and tumor necrosis factor-alpha-1. J Immunol 143, 1989-1995.
    • (1989) J Immunol , vol.143 , pp. 1989-1995
    • Topley, N.1    Floege, J.2    Wessel, K.3    Hass, R.4    Radeke, H.5    Kaever, V.6    Resch, K.7
  • 50
    • 0027423048 scopus 로고
    • Epidermal growth factor potentiates interleukin 1 and tumor necrosis factor-induced prostaglandin biosynthesis in human gingival fibroblasts
    • Modeer T, Yucel-Lindberg T, Lerner UH, and Andersen G (1993). Epidermal growth factor potentiates interleukin 1 and tumor necrosis factor-induced prostaglandin biosynthesis in human gingival fibroblasts. Cytokine 5, 198-204.
    • (1993) Cytokine , vol.5 , pp. 198-204
    • Modeer, T.1    Yucel-Lindberg, T.2    Lerner, U.H.3    Andersen, G.4
  • 51
    • 0031760445 scopus 로고    scopus 로고
    • Cloning and developmental expression, and immunohistochemistry of cyclooxygenase 2 in the endometrium during embryo implantation and gestation in the mink (mustela vision)
    • Song JH, Sirois J, Houde A, and Murphy BD (1998). Cloning and developmental expression, and immunohistochemistry of cyclooxygenase 2 in the endometrium during embryo implantation and gestation in the mink (mustela vision). Endocrinology 139, 3629-3636.
    • (1998) Endocrinology , vol.139 , pp. 3629-3636
    • Song, J.H.1    Sirois, J.2    Houde, A.3    Murphy, B.D.4
  • 52
    • 0029900074 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-beta 1-mediated apoptosis in head and neck squamous cell carcinoma
    • Duffy DC, Calcaterra TC, and Lichtenstein AK (1996). Regulation of transforming growth factor-beta 1-mediated apoptosis in head and neck squamous cell carcinoma. Laryngoscope 106, 889-894.
    • (1996) Laryngoscope , vol.106 , pp. 889-894
    • Duffy, D.C.1    Calcaterra, T.C.2    Lichtenstein, A.K.3
  • 53
    • 0026690059 scopus 로고
    • Induction of apoptosis in cultured hepatocytes and in the regressing liver by transforming growth factor-beta 1 occurs without activation of an endonuclease
    • Oberhammer F, Fritish G, Pavelka M, Froschel G, Tiefenbacher R, Puricho T, and Schulte-Hermann R (1992). Induction of apoptosis in cultured hepatocytes and in the regressing liver by transforming growth factor-beta 1 occurs without activation of an endonuclease. Toxicol Lett 64-65, 701-70.
    • (1992) Toxicol Lett , vol.64-65 , pp. 701-770
    • Oberhammer, F.1    Fritish, G.2    Pavelka, M.3    Froschel, G.4    Tiefenbacher, R.5    Puricho, T.6    Schulte-Hermann, R.7
  • 55
    • 0033080444 scopus 로고    scopus 로고
    • Regulation of proliferation and apoptosis by epidermal growth factor and protein kinase C in human ovarian surface epithelial cells
    • McClellan M, Keivit P, Auersperg N, and Rodland K (1999). Regulation of proliferation and apoptosis by epidermal growth factor and protein kinase C in human ovarian surface epithelial cells. Exp Cell Res 246, 471-479.
    • (1999) Exp Cell Res , vol.246 , pp. 471-479
    • McClellan, M.1    Keivit, P.2    Auersperg, N.3    Rodland, K.4
  • 56
    • 0342716482 scopus 로고    scopus 로고
    • Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture
    • Fabregat I, Sanchez A, Alverez AM, Nakamura T, and Benito M (1996). Epidermal growth factor, but not hepatocyte growth factor, suppresses the apoptosis induced by transforming growth factor-beta in fetal hepatocytes in primary culture. FEBS Lett 384, 14-18.
    • (1996) FEBS Lett , vol.384 , pp. 14-18
    • Fabregat, I.1    Sanchez, A.2    Alverez, A.M.3    Nakamura, T.4    Benito, M.5
  • 57
    • 15844431085 scopus 로고    scopus 로고
    • Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells
    • Fox JC, and Shanley JR (1996). Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells. J Biol Chem 271, 12578-12584.
    • (1996) J Biol Chem , vol.271 , pp. 12578-12584
    • Fox, J.C.1    Shanley, J.R.2
  • 58
    • 0029892754 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 suppress of tumor necrosis factor α-mediated apoptosis requires ras and the activation of mitogen-activated protein kinase
    • Gardner AM, and Johnson GL (1996). Fibroblast growth factor-2 suppress of tumor necrosis factor α-mediated apoptosis requires ras and the activation of mitogen-activated protein kinase. J Biol Chem 271, 14560-14566.
    • (1996) J Biol Chem , vol.271 , pp. 14560-14566
    • Gardner, A.M.1    Johnson, G.L.2
  • 59
    • 0031594902 scopus 로고    scopus 로고
    • 2 inhibits apoptosis in human neutrophilic polymorpho-nuclear leukocytes: Role of intracellular cyclic AMP levels
    • 2 inhibits apoptosis in human neutrophilic polymorpho-nuclear leukocytes: role of intracellular cyclic AMP levels. Exp Hematol 26, 895-902.
    • (1998) Exp Hematol , vol.26 , pp. 895-902
    • Ottonello, L.1    Gonella, R.2    Dapino, P.3    Sacchetti, C.4    Dallegri, F.5
  • 61
    • 0032188853 scopus 로고    scopus 로고
    • NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells
    • Liu X-H, Yao S, Krischenbaum A, and Levine AC (1998). NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells. Cancer Res 58, 4245-4249.
    • (1998) Cancer Res , vol.58 , pp. 4245-4249
    • Liu, X.-H.1    Yao, S.2    Krischenbaum, A.3    Levine, A.C.4
  • 62
    • 0029893722 scopus 로고    scopus 로고
    • Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein
    • Ballif B, Mincek N, Barret J, Wilson M, and Simmons D (1996). Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein. Proc Natl Acad Sci USA 93, 5544-5549.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5544-5549
    • Ballif, B.1    Mincek, N.2    Barret, J.3    Wilson, M.4    Simmons, D.5
  • 63
    • 0028884033 scopus 로고
    • PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi DR, Cuenda A, Cohen P, Dudley DT, and Saltiel AR (1995). PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270, 27489-27494.
    • (1995) J Biol Chem , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 64
    • 0032925126 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascade and transcription factors: The opposite role of MKK3/6-p38K and MKK1-MAPK
    • Terada Y, Nakashima O, Inoshita S, Kuwahara M, Sasaki S, and Marumo F (1999). Mitogen-activated protein kinase cascade and transcription factors: the opposite role of MKK3/6-p38K and MKK1-MAPK. Nephrol Dial Transplant 14, 45-47.
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 45-47
    • Terada, Y.1    Nakashima, O.2    Inoshita, S.3    Kuwahara, M.4    Sasaki, S.5    Marumo, F.6
  • 65
    • 0030961008 scopus 로고    scopus 로고
    • Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction
    • Wang W, Zhou G, Hu MCT, Yao Z, and Tan TH (1997). Activation of the hematopoietic progenitor kinase-1 (HPK1)-dependent, stress-activated c-Jun N-terminal kinase (JNK) pathway by transforming growth factor beta (TGF-beta)-activated kinase (TAK1), a kinase mediator of TGF beta signal transduction. J Biol Chem 272, 22771-22775.
    • (1997) J Biol Chem , vol.272 , pp. 22771-22775
    • Wang, W.1    Zhou, G.2    Hu, M.C.T.3    Yao, Z.4    Tan, T.H.5


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