Hypoxia upregulates PGI-synthase and increases PGI2 release in human vascular cells exposed to inflammatory stimuli

Journal of Lipid Research

Volumn 52, Issue 4, 2011, Pages 720-731

  Camacho, Mercedes ^a   Rodríguez, Cristina ^b   Guadall, Anna ^b   Alcolea, Sonia ^a   Orriols, Mar ^b   Escudero, José Román ^a   Martínez González, José ^b   Vila, Luis ^a  

^a BIOMEDICAL RESEARCH INSTITUTE SANT PAU IIB SANT PAU   (Spain)

^b Institut Català de Ciències Cardiovasculars   (Spain)

Author keywords

Cyclooxygenase pathway; Endothelial cells; Prostacyclin; Prostacyclin synthase; Prostaglandin I synthase; Smooth muscle cells

Indexed keywords

CYCLOOXYGENASE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; MESSENGER RNA; PROSTACYCLIN; PROSTACYCLIN SYNTHASE; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FATTY ACID BLOOD LEVEL; HUMAN; HUMAN CELL; HYPOXIA; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOTTING, WESTERN; CELL HYPOXIA; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYCLOOXYGENASE 2; DINOPROSTONE; ENDOTHELIAL CELLS; EPOPROSTENOL; HUMANS; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;

EID: 79953321199     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M011007     Document Type: Article

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