메뉴 건너뛰기




Volumn 14, Issue 24, 2008, Pages 8221-8227

Cyclooxygenase-2 expression Is an independent predictor of poor prognosis in colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; CYCLOOXYGENASE 2; K RAS PROTEIN; PROTEIN P53; PTGS2 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 58149340659     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-08-1841     Document Type: Article
Times cited : (170)

References (50)
  • 1
    • 30344474930 scopus 로고    scopus 로고
    • Connecting COX-2 and Wnt in cancer
    • Buchanan FG, DuBois RN. Connecting COX-2 and Wnt in cancer. Cancer Cell 2006;9:6-8.
    • (2006) Cancer Cell , vol.9 , pp. 6-8
    • Buchanan, F.G.1    DuBois, R.N.2
  • 2
    • 18444408375 scopus 로고    scopus 로고
    • COX-2: A molecular target for colorectal cancer prevention
    • Brown JR, Du Bois RN. COX-2: a molecular target for colorectal cancer prevention. J Clin Oncol 2005;23:2840-55.
    • (2005) J Clin Oncol , vol.23 , pp. 2840-2855
    • Brown, J.R.1    Du Bois, R.N.2
  • 3
    • 11144224065 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression: A significant prognostic indicator for patients with colorectal cancer
    • Soumaoro LT,UetakeH,Higuchi T,Takagi Y, Enomoto M, Sugihara K. Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer. Clin Cancer Res 2004;10:8465-71.
    • (2004) Clin Cancer Res , vol.10 , pp. 8465-8471
    • Soumaoro, L.T.1    Uetake, H.2    Higuchi, T.3    Takagi, Y.4    Enomoto, M.5    Sugihara, K.6
  • 4
    • 0036120432 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 correlates with advanced stages of colorectal cancer
    • Zhang H, Sun XF. Overexpression of cyclooxygenase-2 correlates with advanced stages of colorectal cancer. Am J Gastroenterol 2002;97:1037-41.
    • (2002) Am J Gastroenterol , vol.97 , pp. 1037-1041
    • Zhang, H.1    Sun, X.F.2
  • 5
    • 33748196958 scopus 로고    scopus 로고
    • Celecoxib for the prevention of sporadic colorectal adenomas
    • Bertagnolli MM, Eagle CJ, Zauber AG, et al. Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med 2006;355:873-84.
    • (2006) N Engl J Med , vol.355 , pp. 873-884
    • Bertagnolli, M.M.1    Eagle, C.J.2    Zauber, A.G.3
  • 6
    • 33748180713 scopus 로고    scopus 로고
    • Celecoxib for the prevention of colorectal adenomatous polyps
    • Arber N, Eagle CJ, Spicak J, et al. Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med 2006;355:885-95.
    • (2006) N Engl J Med , vol.355 , pp. 885-895
    • Arber, N.1    Eagle, C.J.2    Spicak, J.3
  • 7
    • 34248157118 scopus 로고    scopus 로고
    • Effect of aspirin on long-term risk of colorectal cancer: Consistent evidence from randomised and observational studies
    • Flossmann E, Rothwell PM. Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies. Lancet 2007;369:1603-13.
    • (2007) Lancet , vol.369 , pp. 1603-1613
    • Flossmann, E.1    Rothwell, P.M.2
  • 8
    • 0033923699 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer
    • Tomozawa S,Tsuno NH, Sunami E, et al. Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer. Br J Cancer 2000;83:324-8.
    • (2000) Br J Cancer , vol.83 , pp. 324-328
    • Tomozawa, S.1    Tsuno, N.H.2    Sunami, E.3
  • 9
    • 34250330771 scopus 로고    scopus 로고
    • EP1-4 subtype, COX and PPARγ receptor expression in colorectal cancer in prediction of disease-specific mortality
    • Gustafsson A, Hansson E, Kressner U, et al. EP1-4 subtype, COX and PPARγ receptor expression in colorectal cancer in prediction of disease-specific mortality. Int J Cancer 2007;121:232-40.
    • (2007) Int J Cancer , vol.121 , pp. 232-240
    • Gustafsson, A.1    Hansson, E.2    Kressner, U.3
  • 10
    • 0033530260 scopus 로고    scopus 로고
    • The relationship between cyclooxygenase-2 expression and colorectal cancer
    • Sheehan KM, Sheahan K, O'Donoghue DP, et al. The relationship between cyclooxygenase-2 expression and colorectal cancer. JAMA 1999;282:1254-7.
    • (1999) JAMA , vol.282 , pp. 1254-1257
    • Sheehan, K.M.1    Sheahan, K.2    O'Donoghue, D.P.3
  • 11
    • 1642342072 scopus 로고    scopus 로고
    • Microvessel density, cyclo-oxygenase 2 expression, K-ras mutation and p53 overexpression in colonic cancer
    • Liang JT, Huang KC, JengYM, Lee PH, Lai HS, Hsu HC. Microvessel density, cyclo-oxygenase 2 expression, K-ras mutation and p53 overexpression in colonic cancer. Br J Surg 2004;91:355-61.
    • (2004) Br J Surg , vol.91 , pp. 355-361
    • Liang, J.T.1    Huang, K.C.2    Jeng, Y.M.3    Lee, P.H.4    Lai, H.S.5    Hsu, H.C.6
  • 12
    • 27644541404 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human colorectal cancer is unrelated to overall patient survival
    • Fux R, Schwab M,Thon KP, Gleiter CH, FritzP. Cyclooxygenase-2 expression in human colorectal cancer is unrelated to overall patient survival. Clin Cancer Res 2005;11:4754-60.
    • (2005) Clin Cancer Res , vol.11 , pp. 4754-4760
    • Fux, R.1    Schwab, M.2    Thon, K.P.3    Gleiter, C.H.4    Fritz, P.5
  • 13
    • 23644445022 scopus 로고    scopus 로고
    • Prognostic importance of COX-2 expression in patients with co-lorectal cancer
    • YamacD,CelenkogluG,Coskun U, et al.Prognostic importance of COX-2 expression in patients with co-lorectal cancer. Pathol Res Pract 2005;201:497-502.
    • (2005) Pathol Res Pract , vol.201 , pp. 497-502
    • Yamac, D.1    Celenkoglu, G.2    Coskun, U.3
  • 14
    • 0036934482 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 protein in colorectal carcinomas
    • Joo YE, Kim HS, Min SW, et al. Expression of cyclooxygenase-2 protein in colorectal carcinomas. Int J Gastrointest Cancer 2002;31:147-54.
    • (2002) Int J Gastrointest Cancer , vol.31 , pp. 147-154
    • Joo, Y.E.1    Kim, H.S.2    Min, S.W.3
  • 15
    • 0141829772 scopus 로고    scopus 로고
    • Role of COX-2in carcinogenesis of colorectal cancer and its relationship with tumor biological characteristics and patients' prognosis
    • Wu AW,Gu J,Ji JF, Li ZF,XuGW. Role of COX-2in carcinogenesis of colorectal cancer and its relationship with tumor biological characteristics and patients' prognosis. World J Gastroenterol 2003;9:1990-4.
    • (2003) World J Gastroenterol , vol.9 , pp. 1990-1994
    • Wu, A.W.1    Gu, J.2    Ji, J.F.3    Li, Z.F.4    Xu, G.W.5
  • 16
    • 38149029210 scopus 로고    scopus 로고
    • Prognostic significance of cyclooxygenase-2 expression and nuclear p53 accumulation in patients with colorectal cancer
    • Lim SC, Lee TB, Choi CH, Ryu SY, Min YD, Kim KJ. Prognostic significance of cyclooxygenase-2 expression and nuclear p53 accumulation in patients with colorectal cancer. J Surg Oncol 2008;97:51 -6.
    • (2008) J Surg Oncol , vol.97 , pp. 51-56
    • Lim, S.C.1    Lee, T.B.2    Choi, C.H.3    Ryu, S.Y.4    Min, Y.D.5    Kim, K.J.6
  • 18
    • 33745817778 scopus 로고    scopus 로고
    • Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer
    • Ogino S, Brahmandam M, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Neoplasia 2006;8:458-64.
    • (2006) Neoplasia , vol.8 , pp. 458-464
    • Ogino, S.1    Brahmandam, M.2    Kawasaki, T.3    Kirkner, G.J.4    Loda, M.5    Fuchs, C.S.6
  • 19
    • 3643084354 scopus 로고    scopus 로고
    • Reduced COX-2 protein in colorectal cancer with defective mismatch repair
    • Karnes WE, Jr., Shattuck-Brandt R, Burgart LJ, et al. Reduced COX-2 protein in colorectal cancer with defective mismatch repair. Cancer Res 1998;58:5473-7.
    • (1998) Cancer Res , vol.58 , pp. 5473-5477
    • Karnes Jr., W.E.1    Shattuck-Brandt, R.2    Burgart, L.J.3
  • 20
    • 0032815687 scopus 로고    scopus 로고
    • Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers
    • Sinicrope FA, Lemoine M, Xi L, et al. Reduced expression of cyclooxygenase 2 proteins in hereditary nonpolyposis colorectal cancers relative to sporadic cancers. Gastroenterology 1999;117:350-8.
    • (1999) Gastroenterology , vol.117 , pp. 350-358
    • Sinicrope, F.A.1    Lemoine, M.2    Xi, L.3
  • 21
    • 14544300998 scopus 로고    scopus 로고
    • Systematic review of microsatellite instability and colorectal cancer prognosis
    • Popat S, Hubner R, Houlston RS. Systematic review of microsatellite instability and colorectal cancer prognosis. J Clin Oncol 2005;23:609-18.
    • (2005) J Clin Oncol , vol.23 , pp. 609-618
    • Popat, S.1    Hubner, R.2    Houlston, R.S.3
  • 22
    • 0141816863 scopus 로고    scopus 로고
    • Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53
    • Swamy MV, Herzog CR, Rao CV. Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53. Cancer Res 2003; 63:5239-42.
    • (2003) Cancer Res , vol.63 , pp. 5239-5242
    • Swamy, M.V.1    Herzog, C.R.2    Rao, C.V.3
  • 23
    • 33748948050 scopus 로고    scopus 로고
    • Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-κB
    • Benoit V, de Moraes E, Dar NA, et al. Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-κB. Oncogene 2006;25:5708-18.
    • (2006) Oncogene , vol.25 , pp. 5708-5718
    • Benoit, V.1    de Moraes, E.2    Dar, N.A.3
  • 24
    • 18344376930 scopus 로고    scopus 로고
    • The Nurses' Health Study: Lifestyle and health among women
    • Colditz GA, Hankinson SE. The Nurses' Health Study: lifestyle and health among women. Nat Rev Cancer 2005;5:388-96.
    • (2005) Nat Rev Cancer , vol.5 , pp. 388-396
    • Colditz, G.A.1    Hankinson, S.E.2
  • 25
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med 2007;356:2131 -42.
    • (2007) N Engl J Med , vol.356 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 26
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immu-nohistochemistry of mutantp53 gene product in archival colorectal neoplasms
    • Baas IO, Mulder JW, Offerhaus GJ,Vogelstein B, Hamilton SR. An evaluation of six antibodies for immu-nohistochemistry of mutantp53 gene product in archival colorectal neoplasms. J Pathol 1994;172:5-12.
    • (1994) J Pathol , vol.172 , pp. 5-12
    • Baas, I.O.1    Mulder, J.W.2    Offerhaus, G.J.3    Vogelstein, B.4    Hamilton, S.R.5
  • 28
    • 29744450338 scopus 로고    scopus 로고
    • Assessing p53 in clinical contexts: Unlearned lessons and new perspectives
    • Hall PA, McCluggage WG. Assessing p53 in clinical contexts: unlearned lessons and new perspectives. J Pathol 2006;208:1 -6.
    • (2006) J Pathol , vol.208 , pp. 1-6
    • Hall, P.A.1    McCluggage, W.G.2
  • 29
    • 17944392103 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 correlates with chromosomal gain at the cyclooxygenase-2 locus and decreased patient survival in advanced colorectal carcinomas
    • Knosel T, Yu Y, Stein U, et al. Overexpression of cyclooxygenase-2 correlates with chromosomal gain at the cyclooxygenase-2 locus and decreased patient survival in advanced colorectal carcinomas. Dis Colon Rectum 2004;47:70-7.
    • (2004) Dis Colon Rectum , vol.47 , pp. 70-77
    • Knosel, T.1    Yu, Y.2    Stein, U.3
  • 30
    • 23844497341 scopus 로고    scopus 로고
    • Sensitive sequencing method for KRAS mutation detection by pyrosequencing
    • Ogino S, Kawasaki T, Brahmandam M, et al. Sensitive sequencing method for KRAS mutation detection by pyrosequencing. J Mol Diagn 2005;7:413-21.
    • (2005) J Mol Diagn , vol.7 , pp. 413-421
    • Ogino, S.1    Kawasaki, T.2    Brahmandam, M.3
  • 31
    • 33749069927 scopus 로고    scopus 로고
    • CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
    • Ogino S, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations. J Mol Diagn 2006;8:582-8.
    • (2006) J Mol Diagn , vol.8 , pp. 582-588
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3    Loda, M.4    Fuchs, C.S.5
  • 32
    • 34247570795 scopus 로고    scopus 로고
    • Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample
    • Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS. Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. J Mol Diagn 2007;9:305-14.
    • (2007) J Mol Diagn , vol.9 , pp. 305-314
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3    Kraft, P.4    Loda, M.5    Fuchs, C.S.6
  • 33
    • 33744550591 scopus 로고    scopus 로고
    • Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis
    • OginoS, Kawasaki T, Brahmandam M, et al. Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis. J Mol Diagn 2006;8:209-17.
    • (2006) J Mol Diagn , vol.8 , pp. 209-217
    • Ogino, S.1    Kawasaki, T.2    Brahmandam, M.3
  • 34
    • 0034654669 scopus 로고    scopus 로고
    • MethyLight: A high-throughput assay to measure DNA methylation
    • Eads CA, Danenberg KD, Kawakami K, et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 2000;28:E32.
    • (2000) Nucleic Acids Res , vol.28
    • Eads, C.A.1    Danenberg, K.D.2    Kawakami, K.3
  • 35
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger DJ, Siegmund KD, Campan M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006; 38:787-93.
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3
  • 36
    • 22244472992 scopus 로고    scopus 로고
    • Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers
    • Samowitz WS, Sweeney C, Herrick J, et al. Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers. Cancer Res 2005;65:6063-9.
    • (2005) Cancer Res , vol.65 , pp. 6063-6069
    • Samowitz, W.S.1    Sweeney, C.2    Herrick, J.3
  • 37
    • 35948981194 scopus 로고    scopus 로고
    • Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy
    • Shen L, Catalano PJ, Benson AB III, O'Dwyer P, Hamilton SR, Issa JP. Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy. Clin Cancer Res 2007;13:6093-8.
    • (2007) Clin Cancer Res , vol.13 , pp. 6093-6098
    • Shen, L.1    Catalano, P.J.2    Benson III, A.B.3    O'Dwyer, P.4    Hamilton, S.R.5    Issa, J.P.6
  • 38
    • 0142087630 scopus 로고    scopus 로고
    • WardRL,CheongK,KuSL,MeagherA,O'Connor T, Hawkins NJ. Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability. J Clin Oncol 2003;21:3729-36.
    • WardRL,CheongK,KuSL,MeagherA,O'Connor T, Hawkins NJ. Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability. J Clin Oncol 2003;21:3729-36.
  • 39
    • 58249089525 scopus 로고    scopus 로고
    • Ogino S, Nosho K, Kirkner GJ, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 2009: in press (published online on 2 Oct 2008; doi.10.1136/gut.2008.155473) .
    • Ogino S, Nosho K, Kirkner GJ, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut 2009: in press (published online on 2 Oct 2008; doi.10.1136/gut.2008.155473) .
  • 41
    • 25144476901 scopus 로고    scopus 로고
    • Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer
    • Ogino S, Meyerhardt JA, Cantor M, et al. Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer. Clin Cancer Res 2005;11:6650-6.
    • (2005) Clin Cancer Res , vol.11 , pp. 6650-6656
    • Ogino, S.1    Meyerhardt, J.A.2    Cantor, M.3
  • 42
    • 34249801768 scopus 로고    scopus 로고
    • Cycloox-ygenase 2 expression in rectal cancer is of prognostic significance in patients receiving preoperative radiotherapy
    • de Heer P, Gosens MJ, de Bruin EC, et al. Cycloox-ygenase 2 expression in rectal cancer is of prognostic significance in patients receiving preoperative radiotherapy. Clin Cancer Res 2007;13:2955-60.
    • (2007) Clin Cancer Res , vol.13 , pp. 2955-2960
    • de Heer, P.1    Gosens, M.J.2    de Bruin, E.C.3
  • 44
    • 34250189539 scopus 로고    scopus 로고
    • Clinical implications of fibroblast activation protein in patients with colon cancer
    • Henry LR, Lee HO, Lee JS, et al. Clinical implications of fibroblast activation protein in patients with colon cancer. Clin Cancer Res 2007;13:1736-41.
    • (2007) Clin Cancer Res , vol.13 , pp. 1736-1741
    • Henry, L.R.1    Lee, H.O.2    Lee, J.S.3
  • 45
    • 52449122415 scopus 로고    scopus 로고
    • The relative distribution of membranous and cytoplasmic Met is a prognostic indicator in stage I and II colon cancer
    • Ginty F, Adak S, Can A, et al. The relative distribution of membranous and cytoplasmic Met is a prognostic indicator in stage I and II colon cancer. Clin Cancer Res 2008;14:3814-22.
    • (2008) Clin Cancer Res , vol.14 , pp. 3814-3822
    • Ginty, F.1    Adak, S.2    Can, A.3
  • 47
    • 33947432482 scopus 로고    scopus 로고
    • High macrophage infiltration along the tumor front correlates with improved survival in colon cancer
    • Forssell J, Oberg A, Henriksson ML, Stenling R, Jung A, Palmqvist R. High macrophage infiltration along the tumor front correlates with improved survival in colon cancer. Clin Cancer Res 2007;13:1472-9.
    • (2007) Clin Cancer Res , vol.13 , pp. 1472-1479
    • Forssell, J.1    Oberg, A.2    Henriksson, M.L.3    Stenling, R.4    Jung, A.5    Palmqvist, R.6
  • 48
    • 40949089575 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy
    • Morris M, Platell C, Iacopetta B. Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy. Clin Cancer Res 2008;14:1413-7.
    • (2008) Clin Cancer Res , vol.14 , pp. 1413-1417
    • Morris, M.1    Platell, C.2    Iacopetta, B.3
  • 49
    • 0035207130 scopus 로고    scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression correlates with tumor angiogenesis in human colorectal cancer
    • Cianchi F, Cortesini C, Bechi P, et al. Up-regulation of cyclooxygenase 2 gene expression correlates with tumor angiogenesis in human colorectal cancer. Gastroenterology 2001;121:1339-47.
    • (2001) Gastroenterology , vol.121 , pp. 1339-1347
    • Cianchi, F.1    Cortesini, C.2    Bechi, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.