Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma

Diseases of the Esophagus

Volumn 24, Issue 6, 2011, Pages 444-449

  Meng, X Y ^a   Zhu, S T ^b   Zong, Y ^b   Wang, Y J ^b   Li, P ^b   Zhang, S T ^b  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Cyclooxygenase 2; Esophageal neoplasm; Methylation; Promoter regions; Squamous cell carcinoma

Indexed keywords

5 AZA DEOXYCYTIDIN; BISULFITE; CYCLOOXYGENASE 2; DNA METHYLTRANSFERASE INHIBITOR; MESSENGER RNA; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; COLORECTAL CANCER; DNA METHYLATION; EMBRYONIC STEM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FAR WESTERN BLOTTING; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; STOMACH CANCER; UPREGULATION;

AZACITIDINE; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DINOPROSTONE; DNA METHYLATION; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA;

EID: 80051703608     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2010.01159.x     Document Type: Article

References (31)

1. Corley D A, Kerlikowske K, Verma R, Buffler P. Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and meta-analysis. Gastroenterology 2003; 124: 47-56.
2. Vane J R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231: 232-5.
3. Appleby S B, Ristimaki A, Neilson K, Narko K, Hla T. Structure of the human cyclo-oxygenase-2 gene. Biochem J 1994; 302: 723-7.
4. Zimmermann K C, Sarbia M, Weber A A, Borchard F, Gabbert H E, Schror K. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res 1999; 59: 198-204.
5. Shamma A, Yamamoto H, Doki Y etal. Up-regulation of cyclooxygenase-2 in squamous carcinogenesis of the esophagus. Clin Cancer Res 2000; 6: 1229-38.
6. Rashid A, Issa J P. CpG island methylation in gastroenterologic neoplasia: a maturing field. Gastroenterology 2004; 127: 1578-88.
7. Huang L, Zhang K L, Li H etal. Infrequent COX-2 expression due to promoter hypermethylation in gastric cancers in Dalian, China. Hum Pathol 2006; 37: 557-67.
8. Toyota M, Shen L, Ohe-Toyota M, Hamilton S R, Sinicrope F A, Issa J P. Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors. Cancer Res 2000; 60: 4044-8.
9. Murata H, Tsuji S, Tsujii M etal. Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells. Lab Invest 2004; 84: 1050-9.
10. Frommer M, McDonald L E, Millar D S etal. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci USA 1992; 89: 1827-31.
11. Song S H, Jong H S, Choi H H etal. Transcriptional silencing of cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells. Cancer Res 2001; 61: 4628-35.
12. Lee S, Kim W H, Jung H Y, Yang M H, Kang G H. Aberrant CpG island methylation of multiple genes in intrahepatic cholangiocarcinoma. Am J Pathol 2002; 161: 1015-22.
13. Wang B C, Guo C Q, Sun C, Sun Q L, Liu G Y, Li D G. Mechanism and clinical significance of cyclooxygenase-2 expression in gastric cancer. World J Gastroenterol 2005; 11: 3240-4.
14. Ma X, Yang Q, Wilson K T, Kundu N, Meltzer S J, Fulton A M. Promoter methylation regulates cyclooxygenase expression in breast cancer. Breast Cancer Res 2004; 6: R316-21.
15. Clark S J, Harrison J, Molloy P L. Sp1 binding is inhibited by (m)Cp(m)CpG methylation. Gene 1997; 195: 67-71.
16. Prendergast G C, Ziff E B. Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science 1991; 251: 186-9.
17. Yamamoto K, Arakawa T, Ueda N, Yamamoto S. Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J Biol Chem 1995; 270: 31315-20.
18. DuBois R N, Radhika A, Reddy B S, Entingh A J. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology 1996; 110: 1259-62.
19. Dimberg J, Samuelsson A, Hugander A, Soderkvist P. Differential expression of cyclooxygenase 2 in human colorectal cancer. Gut 1999; 45: 730-2.
20. Caput D, Beutler B, Hartog K, Thayer R, Brown-Shimer S, Cerami A. Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators. Proc Natl Acad Sci U S A 1986; 83: 1670-4.
21. Kruys V, Marinx O, Shaw G, Deschamps J, Huez G. Translational blockade imposed by cytokine-derived UA-rich sequences. Science 1989; 245: 852-5.
22. Sheng H, Shao J, Dixon D A etal. Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. J Biol Chem 2000; 275: 6628-35.
23. Dixon D A, Kaplan C D, McIntyre T M, Zimmerman G A, Prescott S M. Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region. J Biol Chem 2000; 275: 11750-7.
24. Hackanson B, Bennett K L, Brena R M etal. Epigenetic modification of CAAT/enhancer binding protein alpha expression in acute myeloid leukemia. Cancer Res 2008; 68: 3142-51.
25. Lu C, Soria J C, Tang X etal. Prognostic factors in resected stage I non-small-cell lung cancer: a multivariate analysis of six molecular markers. J Clin Oncol 2004; 22: 4575-83.
26. Yu J, Leung W K, Lee T L, Tse P C, To K F, Sung J J. Promoter hypermethylation of cyclooxygenase-2 in gastric carcinoma. Int J Oncol 2003; 22: 1025-31.
27. Friedrich M G, Chandrasoma S, Siegmund K D etal. Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma. Eur J Cancer 2005; 41: 2769-78.
28. Akhtar M, Cheng Y, Magno R M etal. Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells. Cancer Res 2001; 61: 2399-403.
29. Toyota M, Shen L, Ohe-Toyota M etal. Aberrant methylation of the cyclooxygenase 2 CpG island in colorectal tumors. Cancer Res 2000; 60: 4044-48.
30. Nishioka K, Doki Y, Miyata H etal. Bile acid promotes the proliferation of squamous cell carcinoma of the esophagus, independent of its inducing COX-2 expression. J Surg Res 2006; 132: 130-5.
31. Aggarwal S, Taneja N, Lin L etal. Indomethacin-induced apoptosis in esophageal adenocarcinoma cells involves upregulation of Bax and translocation of mitochondrial cytochrome C independent of COX-2 expression. Neoplasia 2000; 2: 346-56.