-
1
-
-
0036225281
-
Reaching a genetic and molecular understanding of skeletal development
-
DOI 10.1016/S1534-5807(02)00157-0
-
Karsenty, G., and Wagner, E.F. 2002. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell. 2:389-406. (Pubitemid 34436569)
-
(2002)
Developmental Cell
, vol.2
, Issue.4
, pp. 389-406
-
-
Karsenty, G.1
Wagner, E.F.2
-
2
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy, P., Zhang, R., Geoffroy, V., Ridall, A.L., and Karsenty, G. 1997. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 89:747-754. (Pubitemid 27516177)
-
(1997)
Cell
, vol.89
, Issue.5
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
3
-
-
0037059614
-
The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation
-
DOI 10.1016/S0092-8674(01)00622-5
-
Nakashima, K., et al. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 108:17-29. (Pubitemid 34137009)
-
(2002)
Cell
, vol.108
, Issue.1
, pp. 17-29
-
-
Nakashima, K.1
Zhou, X.2
Kunkel, G.3
Zhang, Z.4
Deng, J.M.5
Behringer, R.R.6
De Crombrugghe, B.7
-
4
-
-
11144357428
-
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology: Implication for Coffin-Lowry syndrome
-
DOI 10.1016/S0092-8674(04)00344-7, PII S0092867404003447
-
Yang, X., et al. 2004. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 117:387-398. (Pubitemid 38534544)
-
(2004)
Cell
, vol.117
, Issue.3
, pp. 387-398
-
-
Yang, X.1
Matsuda, K.2
Bialek, P.3
Jacquot, S.4
Masuoka, H.C.5
Schinke, T.6
Li, L.7
Brancorsini, S.8
Sassone-Corsi, P.9
Townes, T.M.10
Hanauer, A.11
Karsenty, G.12
-
5
-
-
8744224520
-
ATF4, the osteoblast accumulation of which is determined post-translationally, can induce osteoblast-specific gene expression in non-osteoblastic cells
-
DOI 10.1074/jbc.M410010200
-
Yang, X., and Karsenty, G. 2004. ATF4, the osteoblast accumulation of which is determined posttranslationally, can induce osteoblast-specific gene expression in non-osteoblastic cells. J. Biol. Chem. 279:47109-47114. (Pubitemid 39518367)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.45
, pp. 47109-47114
-
-
Yang, X.1
Karsenty, G.2
-
6
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to cxidative stress
-
Harding, H.P., et al. 2003. An integrated stress response regulates amino acid metabolism and resistance to cxidative stress. Mol. Cell. 11:619-633.
-
(2003)
Mol. Cell.
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
-
7
-
-
33751412300
-
ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae
-
DOI 10.1016/j.cmet.2006.10.010, PII S1550413106003391
-
Elefteriou, F., et al. 2006. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab. 4:441-451. (Pubitemid 44817348)
-
(2006)
Cell Metabolism
, vol.4
, Issue.6
, pp. 441-451
-
-
Elefteriou, F.1
Benson, M.D.2
Sowa, H.3
Starbuck, M.4
Liu, X.5
Ron, D.6
Parada, L.7
Karsenty, G.8
-
8
-
-
0043267732
-
Genetic regulation of osteoclast development and function
-
Teitelbaum, S.L., and Ross, F.P. 2003. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4:638-679.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 638-679
-
-
Teitelbaum, S.L.1
Ross, F.P.2
-
9
-
-
15844384047
-
Leptin regulation of bone resorption by the sympathetic nervous system and CART
-
DOI 10.1038/nature03398
-
Elefteriou, F., et al. 2005. Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature. 434:514-520. (Pubitemid 40477060)
-
(2005)
Nature
, vol.434
, Issue.7032
, pp. 514-520
-
-
Elefteriou, F.1
Ahn, J.D.2
Takeda, S.3
Starbuck, M.4
Yang, X.5
Liu, X.6
Kondo, H.7
Richards, W.G.8
Bannon, T.W.9
Noda, M.10
Clement, K.11
Valsse, C.12
Karsenty, G.13
-
10
-
-
34547690686
-
Endocrine regulation of energy metabolism by the skeleton
-
Lee, N.K., et al. 2007. Endocrine regulation of energy metabolism by the skeleton. Cell. 130:456-469.
-
(2007)
Cell.
, vol.130
, pp. 456-469
-
-
Lee, N.K.1
-
11
-
-
42449096306
-
Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice
-
DOI 10.1073/pnas.0711119105
-
Ferron, M., Hinoi, E., Karsenty, G., and Ducy, P. 2008. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proc. Natl. Acad. Sci. U. S. A. 105:5266-5270. (Pubitemid 351738545)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.13
, pp. 5266-5270
-
-
Ferron, M.1
Hinoi, E.2
Karsenty, G.3
Ducy, P.4
-
12
-
-
59449093033
-
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity
-
Hinoi, E., et al. 2008. The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. J. Cell Biol. 183:1235-1242.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 1235-1242
-
-
Hinoi, E.1
-
13
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome
-
DOI 10.1038/78085
-
Delépine, M., et al. 2000. EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat. Genet. 25:406-409. (Pubitemid 32983431)
-
(2000)
Nature Genetics
, vol.25
, Issue.4
, pp. 406-409
-
-
Delepine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Mark Lathrop, G.5
Julier, C.6
-
14
-
-
0034968330
-
-/- mice reveals a role for translational control in secretory cell survival
-
-/- mice reveals a role for translational control in secretory cell survival. Mol. Cell. 7:1153-1163.
-
(2001)
Mol. Cell.
, vol.7
, pp. 1153-1163
-
-
Harding, H.P.1
-
15
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
DOI 10.1016/S1097-2765(01)00265-9
-
Scheuner, D., et al. 2001. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol. Cell. 7:1165-1176. (Pubitemid 32607351)
-
(2001)
Molecular Cell
, vol.7
, Issue.6
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
16
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
DOI 10.1038/nrm2199, PII NRM2199
-
Ron, D., and Walter, P. 2007. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8:519-529. (Pubitemid 46985379)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
17
-
-
44349163999
-
Dephosphorylation of Translation Initiation Factor 2alpha Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice
-
DOI 10.1016/j.cmet.2008.04.011, PII S1550413108001435
-
Oyadomari, S., Harding, H.P., Zhang, Y., Oyadomari, M., and Ron, D. 2008. Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice. Cell Metab. 7:520-532. (Pubitemid 351729207)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 520-532
-
-
Oyadomari, S.1
Harding, H.P.2
Zhang, Y.3
Oyadomari, M.4
Ron, D.5
-
18
-
-
56349162283
-
Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum: An entero-bone endocrine axis
-
Yadav, V.K., et al. 2008. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum: an entero-bone endocrine axis. Cell. 135:825-837.
-
(2008)
Cell.
, vol.135
, pp. 825-837
-
-
Yadav, V.K.1
-
19
-
-
0021864131
-
Glucagon physiology and pathophysiology in the light of new advances
-
Unger, R.H. 1985. Glucagon physiology and pathophysiology in the light of new advances. Diabetologia. 28:574-578.
-
(1985)
Diabetologia
, vol.28
, pp. 574-578
-
-
Unger, R.H.1
-
20
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
DOI 10.1038/nature01667
-
Puigserver, P., et al. 2003. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 423:550-555. (Pubitemid 36648580)
-
(2003)
Nature
, vol.423
, Issue.6939
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
21
-
-
0020613008
-
Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin
-
Granner, D., Andreone, T., Sasaki, K., and Beale, E. 1983. Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin. Nature. 305:549-551.
-
(1983)
Nature
, vol.305
, pp. 549-551
-
-
Granner, D.1
Andreone, T.2
Sasaki, K.3
Beale, E.4
-
22
-
-
0032493725
-
Central role for phosphatidylinositide 3-kinase in the repression of glucose'6-phosphatase gene transcription by insulin
-
DOI 10.1074/jbc.273.32.20144
-
Dickens, M., Svitek, C.A., Culbert, A.A., O'Brien, R.M., and Tavare, J.M. 1998. Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin. J. Biol. Chem. 273:20144-20149. (Pubitemid 28377571)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.32
, pp. 20144-20149
-
-
Dickens, M.1
Svitek, C.A.2
Culbert, A.A.3
O'Brien, R.M.4
Tavare, J.M.5
-
23
-
-
11144244418
-
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes
-
DOI 10.1038/nature03047
-
Wolfrum, C., Asilmaz, E., Luca, E., Friedman, J.M., and Stoffel, M. 2004. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature. 432:1027-1032. (Pubitemid 40052233)
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 1027-1032
-
-
Wolfrum, C.1
Asilmaz, E.2
Luca, E.3
Friedman, J.M.4
Stoffel, M.5
-
24
-
-
0024342083
-
Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans
-
Iynedjian, P.B., et al. 1989. Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. Proc. Natl. Acad. Sci. U. S. A. 86:7838-7842. (Pubitemid 19265281)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.20
, pp. 7838-7842
-
-
Iynedjian, P.B.1
Pilot, P.-R.2
Nouspikel, T.3
Milburn, J.L.4
Quaade, C.5
Hughes, S.6
Ucla, C.7
Newgard, C.B.8
-
25
-
-
0036066319
-
Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator-activated receptor- ligands, glucocorticoids, and insulin
-
Huang, B., Wu, P., Bowker-Kinley, M.M., and Harris, R.A. 2002. Regulation of pyruvate dehydrogenase kinase expression by peroxisome proliferator- activated receptor- ligands, glucocorticoids, and insulin. Diabetes. 51:276-283. (Pubitemid 34764781)
-
(2002)
Diabetes
, vol.51
, Issue.2
, pp. 276-283
-
-
Huang, B.1
Wu, P.2
Bowker-Kinley, M.M.3
Harris, R.A.4
-
26
-
-
33244464562
-
Critical nodes in signalling pathways: Insights into insulin action
-
DOI 10.1038/nrm1837, PII NRM1837
-
Taniguchi, C.M., Emanuelli, B., and Kahn, C.R. 2006. Critical nodes in signaling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 7:85-96. (Pubitemid 43278292)
-
(2006)
Nature Reviews Molecular Cell Biology
, vol.7
, Issue.2
, pp. 85-96
-
-
Taniguchi, C.M.1
Emanuelli, B.2
Kahn, C.R.3
-
27
-
-
55449117637
-
Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice
-
Tolwani, R.J., et al. 2005. Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice. PLoS Genet. 1:e23.
-
(2005)
PLoS Genet.
, vol.1
-
-
Tolwani, R.J.1
-
28
-
-
50649097541
-
Fat and beyond: The diverse biology of PPARgamma
-
Tontonoz, P., and Spiegelman, B.M. 2008. Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77:289-312.
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
29
-
-
0032937751
-
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
-
Rane, S.G., et al. 1999. Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat. Genet. 22:44-52.
-
(1999)
Nat. Genet.
, vol.22
, pp. 44-52
-
-
Rane, S.G.1
-
30
-
-
0035989973
-
Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast
-
DOI 10.1002/dvdy.10100
-
Dacquin, R., Starbuck, M., Schinke, T., and Karsenty, G. 2002. Mouse alpha1(I)-collagen promoter is the best known promoter to drive efficient Cre recombinase expression in osteoblast. Dev. Dyn. 224:245-251. (Pubitemid 34569065)
-
(2002)
Developmental Dynamics
, vol.224
, Issue.2
, pp. 245-251
-
-
Dacquin, R.1
Starbuck, M.2
Schinke, T.3
Karsenty, G.4
-
31
-
-
0023228932
-
Vitamin K counteracts the effect of warfarin in liver but not in bone
-
DOI 10.1016/0049-3848(87)90212-X
-
Price, P.A., and Kaneda, Y. 1987. Vitamin K counteracts the effect of warfarin in liver but not in bone. Thromb. Res. 46:121-131. (Pubitemid 17068374)
-
(1987)
Thrombosis Research
, vol.46
, Issue.1
, pp. 121-131
-
-
Price, P.A.1
Kaneda, Y.2
-
32
-
-
0036578784
-
Disruption of CREB function in brain leads to neurodegeneration
-
DOI 10.1038/ng882
-
Mantamadiotis, T., et al. 2002. Disruption of CREB function in brain leads to neurodegeneration. Nat. Genet. 31:47-54. (Pubitemid 34887637)
-
(2002)
Nature Genetics
, vol.31
, Issue.1
, pp. 47-54
-
-
Mantamadiotis, T.1
Lemberger, T.2
Bleckmann, S.C.3
Kern, H.4
Kretz, O.5
Villalba, A.M.6
Tronche, F.7
Kellendonk, C.8
Gau, D.9
Kapfhammer, J.10
Otto, C.11
Schmid, W.12
Schutz, G.13
-
33
-
-
1842457067
-
Knock-In of Nuclear Localised beta-Galactosidase Reveals that the Tyrosine Phosphatase Ptprv Is Specifically Expressed in Cells of the Bone Collar
-
DOI 10.1002/dvdy.20003
-
Dacquin, R., et al. 2004. Knock-in nuclear localized beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev. Dyn. 229:826-834. (Pubitemid 38429111)
-
(2004)
Developmental Dynamics
, vol.229
, Issue.4
, pp. 826-834
-
-
Dacquin, R.1
Mee, P.J.2
Kawaguchi, J.3
Olmsted-Davis, E.A.4
Gallagher, J.A.5
Nichols, J.6
Lee, K.7
Karsenty, G.8
Smith, A.9
-
34
-
-
18544407572
-
Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy
-
Ueki, K., et al. 2000. Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy. J. Clin. Invest. 105:1437-1445. (Pubitemid 30322409)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.10
, pp. 1437-1445
-
-
Ueki, K.1
Yamauchi, T.2
Tamemoto, H.3
Tobe, K.4
Yamamoto-Honda, R.5
Kaburagi, Y.6
Akanuma, Y.7
Yazaki, Y.8
Aizawa, S.9
Nagai, R.10
Kadowaki, T.11
|