Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

Experimental Cell Research

Volumn 314, Issue 5, 2008, Pages 950-960

  Reijonen, Sami ^a   Putkonen, Noora ^a   Nørremølle, Anne ^b   Lindholm, Dan ^a,c   Korhonen, Laura ^a  

^a MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Caspase; Cell death; Endoplasmic reticulum stress; Huntington's disease; PC6.3 cell; Salubrinal

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 12; CASPASE 3; CHAPERONE; CYTOCHROME C; GLUCOSE REGULATED PROTEIN 78; HUNTINGTIN; POLYGLUTAMINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EUKARYOTE; HUMAN; HUMAN CELL; NERVE CELL; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; STRESS; UPREGULATION;

EUKARYOTA;

EID: 39649114320     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.12.025     Document Type: Article

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