메뉴 건너뛰기




Volumn 22, Issue 1, 2012, Pages 17-35

Carbon source metabolism and its regulation in cancer cells

Author keywords

C Myc; Glutaminolysis; HIF 1; MAPK; Metabolism; PI3K; Warburg effect

Indexed keywords

2 OXOGLUTARIC ACID; ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE; AMINO ACID; BIOLOGICAL MARKER; CARBOHYDRATE; CARBONATE DEHYDRATASE IX; ENOLASE; FATTY ACID SYNTHASE; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLUCOSE TRANSPORTER 4; GLUTAMINE; GLUTATHIONE DISULFIDE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HEXOKINASE; HYPOXIA INDUCIBLE FACTOR 1; LACTATE DEHYDROGENASE; LIPID; MONOCARBOXYLATE TRANSPORTER 4; MYC PROTEIN; PROTEIN P53; PYRUVATE DEHYDROGENASE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOREDOXIN INTERACTING PROTEIN; TRICARBOXYLIC ACID;

EID: 84860316773     PISSN: 10454403     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevEukarGeneExpr.v22.i1.20     Document Type: Review
Times cited : (54)

References (129)
  • 1
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science. 1956;123:309-14.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 2
    • 0036717382 scopus 로고    scopus 로고
    • Molecular imaging of cancer with positron emission tomography
    • Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer. 2002;2:683-93.
    • (2002) Nat Rev Cancer , vol.2 , pp. 683-693
    • Gambhir, S.S.1
  • 3
    • 0036176751 scopus 로고    scopus 로고
    • Positron emission tomography scanning: Current and future applications
    • Czernin J, Phelps ME. Positron emission tomography scanning: current and future applications. Annu Rev Med. 2002;53:8-112.
    • (2002) Annu Rev Med , vol.53 , pp. 8-112
    • Czernin, J.1    Phelps, M.E.2
  • 4
    • 0001572284 scopus 로고
    • Nutrition needs of mammalian cells in tissue culture
    • Eagle H. Nutrition needs of mammalian cells in tissue culture. Science. 1955;122:501-14.
    • (1955) Science , vol.122 , pp. 501-514
    • Eagle, H.1
  • 5
    • 0006784093 scopus 로고
    • Glutamine metabolism in Ehrlich ascites-carcinoma cells
    • Coles NW, Johnstone RM. Glutamine metabolism in Ehrlich ascites-carcinoma cells. Biochem J. 1962;83:284-91.
    • (1962) Biochem J , vol.83 , pp. 284-291
    • Coles, N.W.1    Johnstone, R.M.2
  • 6
    • 0018386209 scopus 로고
    • Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells
    • Reitzer LJ, Wice BM, Kennell D. Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells. J Biol Chem. 1979;254:2669-76.
    • (1979) J Biol Chem , vol.254 , pp. 2669-2676
    • Reitzer, L.J.1    Wice, B.M.2    Kennell, D.3
  • 7
    • 0021366190 scopus 로고
    • Glutamine: A major energy source for cultured mammalian cells
    • Zielke HR, Zielke CL, Ozand PT. Glutamine: a major energy source for cultured mammalian cells. Fed Proc. 1984;43:121-5.
    • (1984) Fed Proc , vol.43 , pp. 121-125
    • Zielke, H.R.1    Zielke, C.L.2    Ozand, P.T.3
  • 8
    • 0025109484 scopus 로고
    • Glutaminolysis and glycolysis interactions in proliferant cells
    • Medina MA, Nunez de Castro I. Glutaminolysis and glycolysis interactions in proliferant cells. Int J Biochem. 1990;22:681-3.
    • (1990) Int J Biochem , vol.22 , pp. 681-683
    • Medina, M.A.1    de Nunez, C.I.2
  • 9
    • 77958478353 scopus 로고    scopus 로고
    • Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells
    • Meng M, Chen S, Lao T, Liang D, Sang N. Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells. Cell Cycle. 2010;9:3921-32.
    • (2010) Cell Cycle , vol.9 , pp. 3921-3932
    • Meng, M.1    Chen, S.2    Lao, T.3    Liang, D.4    Sang, N.5
  • 10
    • 37449034854 scopus 로고    scopus 로고
    • Thomson CB Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
    • DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thomson CB Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A. 2007;104:19345-50.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 19345-19350
    • Deberardinis, R.J.1    Mancuso, A.2    Daikhin, E.3    Nissim, I.4    Yudkoff, M.5    Wehrli, S.6
  • 11
    • 67649484365 scopus 로고    scopus 로고
    • Structural insight into the autoinhibition mechanism of AMP-activated protein kinase
    • Chen L, Jiao ZH, Zheng LS, Zhang YY, Xie ST, Wang ZX, Wu JW. Structural insight into the autoinhibition mechanism of AMP-activated protein kinase. Nature. 2009;459:1146-9.
    • (2009) Nature , vol.459 , pp. 1146-1149
    • Chen, L.1    Jiao, Z.H.2    Zheng, L.S.3    Zhang, Y.Y.4    Xie, S.T.5    Wang, Z.X.6    Wu, J.W.7
  • 13
    • 0029910018 scopus 로고    scopus 로고
    • Characterization of the AMP-ac-tivated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
    • Hawley SA, Davison M, Woods A, Davies SP, Beri RK, Carling D, Hardie DG. Characterization of the AMP-ac-tivated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J Biol Chem. 1996;271:27879-87.
    • (1996) J Biol Chem , vol.271 , pp. 27879-27887
    • Hawley, S.A.1    Davison, M.2    Woods, A.3    Davies, S.P.4    Beri, R.K.5    Carling, D.6    Hardie, D.G.7
  • 14
    • 0029561919 scopus 로고
    • 5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC
    • Davies SP, Helps NR, Cohen PT, Hardie DG. 5'-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC. FEBS Lett. 1995;377:421-5.
    • (1995) FEBS Lett , vol.377 , pp. 421-425
    • Davies, S.P.1    Helps, N.R.2    Cohen, P.T.3    Hardie, D.G.4
  • 15
    • 34147152841 scopus 로고    scopus 로고
    • Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
    • Sanders MJ, Grondin PO, Hegarty BD, Snowden MA, Carling D. Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem J. 2007;403:139-48.
    • (2007) BioChem J , vol.403 , pp. 139-148
    • Sanders, M.J.1    Grondin, P.O.2    Hegarty, B.D.3    Snowden, M.A.4    Carling, D.5
  • 16
    • 85047689953 scopus 로고
    • 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells
    • Corton JM, Gillespie JG, Hawley SA, Hardie DG. 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem. 1995;229:558-65.
    • (1995) Eur J Biochem , vol.229 , pp. 558-565
    • Corton, J.M.1    Gillespie, J.G.2    Hawley, S.A.3    Hardie, D.G.4
  • 17
    • 0029005507 scopus 로고
    • Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase
    • Henin N, Vincent MF, Gruber HE, Van den Berghe G. Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase. FASEB J. 1995;9:541-6.
    • (1995) FASEB J , vol.9 , pp. 541-546
    • Henin, N.1    Vincent, M.F.2    Gruber, H.E.3    van den Berghe, G.4
  • 19
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell. 2003;115:577-90.
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 20
    • 0037163076 scopus 로고    scopus 로고
    • The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase
    • Marsin AS, Bouzin C, Bertrand L, Hue L. The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase. J Biol Chem. 2002;277:30778-83.
    • (2002) J Biol Chem , vol.277 , pp. 30778-30783
    • Marsin, A.S.1    Bouzin, C.2    Bertrand, L.3    Hue, L.4
  • 21
    • 0031425839 scopus 로고    scopus 로고
    • AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
    • Merrill GF, Kurth EJ, Hardie DG, Winder WW. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol. 1997;273:E1107-12.
    • (1997) Am J Physiol , vol.273
    • Merrill, G.F.1    Kurth, E.J.2    Hardie, D.G.3    Winder, W.W.4
  • 23
    • 0032765396 scopus 로고    scopus 로고
    • 5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle
    • Kurth-Kraczek EJ, Hirshman MF, Goodyear LJ, Winder WW. 5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle. Diabetes. 1999;48:1667-71.
    • (1999) Diabetes , vol.48 , pp. 1667-1671
    • Kurth-Kraczek, E.J.1    Hirshman, M.F.2    Goodyear, L.J.3    Winder, W.W.4
  • 24
    • 0032704115 scopus 로고    scopus 로고
    • Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
    • Holmes BF, Kurth-Kraczek EJ, Winder WW. Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J Appl Physiol. 1999;87:1990-5.
    • (1999) J Appl Physiol , vol.87 , pp. 1990-1995
    • Holmes, B.F.1    Kurth-Kraczek, E.J.2    Winder, W.W.3
  • 25
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • Zong H, Ren JM, Young LH, Pypaert M, Mu J, Birnbaum MJ, Shulman GI. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc Natl Acad Sci U S A. 2002;99:15983-7.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3    Pypaert, M.4    Mu, J.5    Birnbaum, M.J.6    Shulman, G.I.7
  • 27
    • 34547914798 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia
    • Bell EL, Klimova TA, Eisenbart J, Schumacker PT, Chandel NS. Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia. Mol Cell Biol. 2007;27:5737-45.
    • (2007) Mol Cell Biol , vol.27 , pp. 5737-5745
    • Bell, E.L.1    Klimova, T.A.2    Eisenbart, J.3    Schumacker, P.T.4    Chandel, N.S.5
  • 30
    • 0036081753 scopus 로고    scopus 로고
    • Cytochrome c release from mitochondria in the aging heart: A possible mechanism for apoptosis with age
    • Phaneuf S, Leeuwenburgh C. Cytochrome c release from mitochondria in the aging heart: a possible mechanism for apoptosis with age. Am J Physiol Regul Integr Comp Physiol. 2002;282:R423-30.
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.282
    • Phaneuf, S.1    Leeuwenburgh, C.2
  • 31
    • 0037458619 scopus 로고    scopus 로고
    • Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
    • Han D, Antunes F, Canali R, Rettori D, Cadenas E. Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem. 2003;278:5557-63.
    • (2003) J Biol Chem , vol.278 , pp. 5557-5563
    • Han, D.1    Antunes, F.2    Canali, R.3    Rettori, D.4    Cadenas, E.5
  • 33
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest. 2002;109:1125-31.
    • (2002) J Clin Invest , vol.109 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 34
    • 63649087890 scopus 로고    scopus 로고
    • Biological role of liver X receptors
    • Baranowski M. Biological role of liver X receptors. J Physiol Pharmacol. 2008;59 Suppl 7:31-55.
    • (2008) J Physiol Pharmacol , vol.59 , Issue.SUPPL. 7 , pp. 31-55
    • Baranowski, M.1
  • 35
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer N, Tontonoz P. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest. 2006;116:607-14.
    • (2006) J Clin Invest , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 36
    • 34447093179 scopus 로고    scopus 로고
    • The integration of lipid-sensing and anti-inflammatory effects: How the PPARs play a role in metabolic balance
    • Nunn AV, Bell J, Barter P. The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance. Nucl Recept. 2007;5:1.
    • (2007) Nucl Recept , vol.5 , pp. 1
    • Nunn, A.V.1    Bell, J.2    Barter, P.3
  • 38
    • 76049100577 scopus 로고    scopus 로고
    • HIF-1: Upstream and downstream of cancer metabolism
    • Semenza GL. HIF-1: upstream and downstream of cancer metabolism. Curr Opin Genet Dev. 2010;20:51-6.
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 51-56
    • Semenza, G.L.1
  • 39
    • 33644622570 scopus 로고    scopus 로고
    • HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
    • Papandreou I, Cairns RA, Fontana L, Lim AL, Denko NC. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab. 2006;3:187-97.
    • (2006) Cell Metab , vol.3 , pp. 187-197
    • Papandreou, I.1    Cairns, R.A.2    Fontana, L.3    Lim, A.L.4    Denko, N.C.5
  • 40
    • 33644614520 scopus 로고    scopus 로고
    • HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
    • Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006;3:177-85.
    • (2006) Cell Metab , vol.3 , pp. 177-185
    • Kim, J.W.1    Tchernyshyov, I.2    Semenza, G.L.3    Dang, C.V.4
  • 42
    • 58249094845 scopus 로고    scopus 로고
    • Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
    • Chiche J, Ilc K, Laferriere J, Trottier E, Dayan F, Mazure NM, Brahimi-Horn MC, Pouyssegur J. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res. 2009;69:358-68.
    • (2009) Cancer Res , vol.69 , pp. 358-368
    • Chiche, J.1    Ilc, K.2    Laferriere, J.3    Trottier, E.4    Dayan, F.5    Mazure, N.M.6    Brahimi-Horn, M.C.7    Pouyssegur, J.8
  • 43
    • 57649130593 scopus 로고    scopus 로고
    • Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance
    • Lu CW, Lin SC, Chen KF, Lai YY, Tsai SJ. Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance. J Biol Chem. 2008;283:28106-14.
    • (2008) J Biol Chem , vol.283 , pp. 28106-28114
    • Lu, C.W.1    Lin, S.C.2    Chen, K.F.3    Lai, Y.Y.4    Tsai, S.J.5
  • 46
    • 35649014840 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
    • Kim JW, Gao P, Liu YC, Semenza GL, Dang CV. Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol Cell Biol. 2007;27:7381-93.
    • (2007) Mol Cell Biol , vol.27 , pp. 7381-7393
    • Kim, J.W.1    Gao, P.2    Liu, Y.C.3    Semenza, G.L.4    Dang, C.V.5
  • 48
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • Lakin ND, Jackson SP. Regulation of p53 in response to DNA damage. Oncogene. 1999;18:7644-55.
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 49
    • 80053036165 scopus 로고    scopus 로고
    • The Role of p53 in Metabolic Regulation
    • Puzio-Kuter AM. The Role of p53 in Metabolic Regulation. Genes Cancer. 2011;2:385-91.
    • (2011) Genes Cancer , vol.2 , pp. 385-391
    • Puzio-Kuter, A.M.1
  • 52
    • 1942506067 scopus 로고    scopus 로고
    • The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
    • Schwartzenberg-Bar-Yoseph F, Armoni M, Karnieli E. The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res. 2004;64:2627-33.
    • (2004) Cancer Res , vol.64 , pp. 2627-2633
    • Schwartzenberg-Bar-Yoseph, F.1    Armoni, M.2    Karnieli, E.3
  • 56
    • 77952212178 scopus 로고    scopus 로고
    • Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
    • Hu W, Zhang C, Wu R, Sun Y, Levine A, Feng Z. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc Natl Acad Sci U S A. 2010;107:7455-60.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7455-7460
    • Hu, W.1    Zhang, C.2    Wu, R.3    Sun, Y.4    Levine, A.5    Feng, Z.6
  • 58
    • 77958492734 scopus 로고    scopus 로고
    • Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells?
    • Dang CV. Glutaminolysis: supplying carbon or nitrogen or both for cancer cells? Cell Cycle. 2010;9:3884-6.
    • (2010) Cell Cycle , vol.9 , pp. 3884-3886
    • Dang, C.V.1
  • 59
    • 79957983577 scopus 로고    scopus 로고
    • Targeting the PI3K/Akt/mTOR pathway--beyond rapalogs
    • Markman B, Dienstmann R, Tabernero J. Targeting the PI3K/Akt/mTOR pathway--beyond rapalogs. Oncotarget. 2010;1:530-43.
    • (2010) OncotarGet , vol.1 , pp. 530-543
    • Markman, B.1    Dienstmann, R.2    Tabernero, J.3
  • 62
    • 67649814136 scopus 로고    scopus 로고
    • PI3K/PTEN signaling in angiogenesis and tumorigenesis
    • Jiang BH, Liu LZ. PI3K/PTEN signaling in angiogenesis and tumorigenesis. Adv Cancer Res. 2009;102:19-65.
    • (2009) Adv Cancer Res , vol.102 , pp. 19-65
    • Jiang, B.H.1    Liu, L.Z.2
  • 63
    • 79955779584 scopus 로고    scopus 로고
    • mTOR links oncogenic signaling to tumor cell metabolism
    • Yecies JL, Manning BD. mTOR links oncogenic signaling to tumor cell metabolism. J Mol Med (Berl). 2011;89:221-8.
    • (2011) J Mol Med (Berl) , vol.89 , pp. 221-228
    • Yecies, J.L.1    Manning, B.D.2
  • 65
    • 60549111398 scopus 로고    scopus 로고
    • Is Akt the "Warburg kinase"?-Aktenergy metabolism interactions and oncogenesis
    • Robey RB, Hay N. Is Akt the "Warburg kinase"?-Aktenergy metabolism interactions and oncogenesis. Semin Cancer Biol. 2009;19:25-31.
    • (2009) Semin Cancer Biol , vol.19 , pp. 25-31
    • Robey, R.B.1    Hay, N.2
  • 66
    • 0034234794 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase is required for transcriptional activity of F-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: Assessment of the role of protein kinase B and p70 S6 kinase
    • Fernandez de Mattos S, de los Pinos EE, Joaquin M, Tauler A. Activation of phosphatidylinositol 3-kinase is required for transcriptional activity of F-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: assessment of the role of protein kinase B and p70 S6 kinase. Biochem J. 2000;349:59-65.
    • (2000) BioChem J , vol.349 , pp. 59-65
    • de Fernandez, M.S.1    de los Pinos, E.E.2    Joaquin, M.3    Tauler, A.4
  • 67
    • 0030748651 scopus 로고    scopus 로고
    • Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades
    • Deprez J, Vertommen D, Alessi DR, Hue L, Rider MH. Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J Biol Chem. 1997;272:17269-75.
    • (1997) J Biol Chem , vol.272 , pp. 17269-17275
    • Deprez, J.1    Vertommen, D.2    Alessi, D.R.3    Hue, L.4    Rider, M.H.5
  • 70
    • 77957753195 scopus 로고    scopus 로고
    • Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation
    • Huang YC, Chang WL, Huang SF, Lin CY, Lin HC, Chang TC. Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation. Eur J Pharmacol. 2010;648:39-49.
    • (2010) Eur J Pharmacol , vol.648 , pp. 39-49
    • Huang, Y.C.1    Chang, W.L.2    Huang, S.F.3    Lin, C.Y.4    Lin, H.C.5    Chang, T.C.6
  • 71
    • 0037072780 scopus 로고    scopus 로고
    • The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes
    • Berwick DC, Hers I, Heesom KJ, Moule SK, Tavare JM. The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes. J Biol Chem. 2002;277:33895-33900.
    • (2002) J Biol Chem , vol.277 , pp. 33895-33900
    • Berwick, D.C.1    Hers, I.2    Heesom, K.J.3    Moule, S.K.4    Tavare, J.M.5
  • 74
    • 0036469122 scopus 로고    scopus 로고
    • Role of the phosphatidylinositol 3'-kinase/ PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells
    • Van de Sande T, De Schrijver E, Heyns W, Verhoeven G, Swinnen JV. Role of the phosphatidylinositol 3'-kinase/ PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells. Cancer Res. 2002;62:642-6.
    • (2002) Cancer Res , vol.62 , pp. 642-646
    • Van de Sande, T.1    de Schrijver, E.2    Heyns, W.3    Verhoeven, G.4    Swinnen, J.V.5
  • 75
    • 19944398464 scopus 로고    scopus 로고
    • High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB
    • Van de Sande T, Roskams T, Lerut E, Joniau S, Van Poppel H, Verhoeven G, Swinnen JV. High-level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB. J Pathol. 2005;206:214-9.
    • (2005) J Pathol , vol.206 , pp. 214-219
    • Van de Sande, T.1    Roskams, T.2    Lerut, E.3    Joniau, S.4    Van Poppel, H.5    Verhoeven, G.6    Swinnen, J.V.7
  • 76
    • 79960907910 scopus 로고    scopus 로고
    • The MAPK cascades: Signaling components, nuclear roles and mechanisms of nuclear translocation
    • Plotnikov A, Zehorai E, Procaccia S, Seger R. The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. Biochim Biophys Acta. 2011;1813:1619-33.
    • (2011) Biochim BioPhys Acta , vol.1813 , pp. 1619-1633
    • Plotnikov, A.1    Zehorai, E.2    Procaccia, S.3    Seger, R.4
  • 77
    • 79953163484 scopus 로고    scopus 로고
    • MAPK signaling in inflammation-associated cancer development
    • Huang P, Han J, Hui L. MAPK signaling in inflammation-associated cancer development. Protein Cell. 2010;1:218-26.
    • (2010) Protein Cell , vol.1 , pp. 218-226
    • Huang, P.1    Han, J.2    Hui, L.3
  • 78
    • 34547204160 scopus 로고    scopus 로고
    • The MEK/ERK cascade: From signaling specificity to diverse functions
    • Shaul YD, Seger R. The MEK/ERK cascade: from signaling specificity to diverse functions. Biochim Biophys Acta. 2007;1773:1213-26.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1213-1226
    • Shaul, Y.D.1    Seger, R.2
  • 79
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • Raman M, Chen W, Cobb MH. Differential regulation and properties of MAPKs. Oncogene. 2007;26:3100-12.
    • (2007) Oncogene , vol.26 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 80
    • 36849000872 scopus 로고    scopus 로고
    • Canonical and alternative MAPK signaling
    • Pimienta G, Pascual J. Canonical and alternative MAPK signaling. Cell Cycle. 2007;6:2628-32.
    • (2007) Cell Cycle , vol.6 , pp. 2628-2632
    • Pimienta, G.1    Pascual, J.2
  • 81
    • 3342944401 scopus 로고    scopus 로고
    • Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: A mechanism for impaired cellular proliferation
    • Harmon AW, Patel YM. Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: a mechanism for impaired cellular proliferation. Breast Cancer Res Treat. 2004;85:103-10.
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 103-110
    • Harmon, A.W.1    Patel, Y.M.2
  • 82
    • 78649737749 scopus 로고    scopus 로고
    • Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling
    • Marko AJ, Miller RA, Kelman A, Frauwirth KA. Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling. PloS One. 2010;5:e15425.
    • (2010) PloS One , vol.5
    • Marko, A.J.1    Miller, R.A.2    Kelman, A.3    Frauwirth, K.A.4
  • 83
    • 0032725554 scopus 로고    scopus 로고
    • P42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
    • Richard DE, Berra E, Gothie E, Roux D, Pouyssegur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. J Biol Chem. 1999;274:32631-7.
    • (1999) J Biol Chem , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothie, E.3    Roux, D.4    Pouyssegur, J.5
  • 84
    • 0037515549 scopus 로고    scopus 로고
    • MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300
    • Sang N, Stiehl DP, Bohensky J, Leshchinsky I, Srinivas V, Caro J. MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J Biol Chem. 2003;278:14013-9.
    • (2003) J Biol Chem , vol.278 , pp. 14013-14019
    • Sang, N.1    Stiehl, D.P.2    Bohensky, J.3    Leshchinsky, I.4    Srinivas, V.5    Caro, J.6
  • 85
    • 17444431201 scopus 로고    scopus 로고
    • Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
    • Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP. Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell. 2005;121:179-93.
    • (2005) Cell , vol.121 , pp. 179-193
    • Ma, L.1    Chen, Z.2    Erdjument-Bromage, H.3    Tempst, P.4    Pandolfi, P.P.5
  • 88
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer. 2008;8:976-90.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 89
    • 67649472398 scopus 로고    scopus 로고
    • Novel anticancer targets: Revisiting ERBB2 and discovering ERBB3
    • Baselga J, Swain SM. Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer. 2009;9:463-75.
    • (2009) Nat Rev Cancer , vol.9 , pp. 463-475
    • Baselga, J.1    Swain, S.M.2
  • 91
    • 76249110471 scopus 로고    scopus 로고
    • Rethinking the Warburg effect with Myc micromanaging glutamine metabolism
    • Dang CV. Rethinking the Warburg effect with Myc micromanaging glutamine metabolism. Cancer Res. 2010;70:859-62.
    • (2010) Cancer Res , vol.70 , pp. 859-862
    • Dang, C.V.1
  • 93
    • 44349149476 scopus 로고    scopus 로고
    • Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression
    • Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, Ayer DE. Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proc Natl Acad Sci U S A. 2008;105:6912-7.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6912-6917
    • Stoltzman, C.A.1    Peterson, C.W.2    Breen, K.T.3    Muoio, D.M.4    Billin, A.N.5    Ayer, D.E.6
  • 94
    • 77953366814 scopus 로고    scopus 로고
    • Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer
    • Peterson CW, Stoltzman CA, Sighinolfi MP, Han KS, Ayer DE. Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer. Mol Cell Biol. 2010;30:2887-95.
    • (2010) Mol Cell Biol , vol.30 , pp. 2887-2895
    • Peterson, C.W.1    Stoltzman, C.A.2    Sighinolfi, M.P.3    Han, K.S.4    Ayer, D.E.5
  • 95
    • 0030583599 scopus 로고    scopus 로고
    • Identification of a carbohydrate response element in rat S14 gene
    • Harmon JS, Mariash CN. Identification of a carbohydrate response element in rat S14 gene. Mol Cell Endocrinol. 1996;123:37-44.
    • (1996) Mol Cell Endocrinol , vol.123 , pp. 37-44
    • Harmon, J.S.1    Mariash, C.N.2
  • 96
    • 0030753971 scopus 로고    scopus 로고
    • Regulation of the expression of lipogenic enzyme genes by carbohydrate
    • Towle HC, Kaytor EN, Shih HM. Regulation of the expression of lipogenic enzyme genes by carbohydrate. Annu Rev Nutr. 1997;17:405-33.
    • (1997) Annu Rev Nutr , vol.17 , pp. 405-433
    • Towle, H.C.1    Kaytor, E.N.2    Shih, H.M.3
  • 97
    • 0034644780 scopus 로고    scopus 로고
    • Glucose regulation of gene transcription
    • Vaulont S, Vasseur-Cognet M, Kahn A. Glucose regulation of gene transcription. J Biol Chem. 2000;275:31555-8.
    • (2000) J Biol Chem , vol.275 , pp. 31555-31558
    • Vaulont, S.1    Vasseur-Cognet, M.2    Kahn, A.3
  • 99
    • 33746536677 scopus 로고    scopus 로고
    • Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
    • Uyeda K, Repa JJ. Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab. 2006;4:107-10.
    • (2006) Cell Metab , vol.4 , pp. 107-110
    • Uyeda, K.1    Repa, J.J.2
  • 100
    • 33749407193 scopus 로고    scopus 로고
    • ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver
    • Ma L, Robinson LN, Towle HC. ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liver. J Biol Chem. 2006;281:28721-30.
    • (2006) J Biol Chem , vol.281 , pp. 28721-28730
    • Ma, L.1    Robinson, L.N.2    Towle, H.C.3
  • 101
    • 0034462487 scopus 로고    scopus 로고
    • MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network
    • Billin AN, Eilers AL, Coulter KL, Logan JS, Ayer DE. MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network. Mol Cell Biol. 2000;20:8845-54.
    • (2000) Mol Cell Biol , vol.20 , pp. 8845-8854
    • Billin, A.N.1    Eilers, A.L.2    Coulter, K.L.3    Logan, J.S.4    Ayer, D.E.5
  • 102
    • 38449087713 scopus 로고    scopus 로고
    • ChREBP, a transcriptional regulator of glucose and lipid metabolism
    • Postic C, Dentin R, Denechaud PD, Girard J. ChREBP, a transcriptional regulator of glucose and lipid metabolism. Annu Rev Nutr. 2007;27:179-92.
    • (2007) Annu Rev Nutr , vol.27 , pp. 179-192
    • Postic, C.1    Dentin, R.2    Denechaud, P.D.3    Girard, J.4
  • 103
    • 2442435802 scopus 로고    scopus 로고
    • Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
    • Iizuka K, Bruick RK, Liang G, Horton JD, Uyeda K. Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis. Proc Natl Acad Sci U S A. 2004;101:7281-6.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7281-7286
    • Iizuka, K.1    Bruick, R.K.2    Liang, G.3    Horton, J.D.4    Uyeda, K.5
  • 104
    • 71649114159 scopus 로고    scopus 로고
    • Transcriptional regulation of tumor suppressor p53 by cAMP-responsive elementbinding protein/AMP-activated protein kinase complex in response to glucose deprivation
    • Okoshi R, Ando K, Suenaga Y, Sang M, Kubo N, Kizaki H, Nakagawara A, Ozaki T. Transcriptional regulation of tumor suppressor p53 by cAMP-responsive elementbinding protein/AMP-activated protein kinase complex in response to glucose deprivation. Genes Cells. 2009;14:1429-40.
    • (2009) Genes Cells , vol.14 , pp. 1429-1440
    • Okoshi, R.1    Ando, K.2    Suenaga, Y.3    Sang, M.4    Kubo, N.5    Kizaki, H.6    Nakagawara, A.7    Ozaki, T.8
  • 106
    • 77952003302 scopus 로고    scopus 로고
    • AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma
    • Kim MJ, Park IJ, Yun H, Kang I, Choe W, Kim SS, Ha J. AMP-activated protein kinase antagonizes pro-apoptotic extracellular signal-regulated kinase activation by inducing dual-specificity protein phosphatases in response to glucose deprivation in HCT116 carcinoma. J Biol Chem. 2010;285:14617-27.
    • (2010) J Biol Chem , vol.285 , pp. 14617-14627
    • Kim, M.J.1    Park, I.J.2    Yun, H.3    Kang, I.4    Choe, W.5    Kim, S.S.6    Ha, J.7
  • 107
    • 62349136030 scopus 로고    scopus 로고
    • AMP kinase signaling determines whether c-Jun N-terminal kinase promotes survival or apoptosis during glucose deprivation
    • Yun H, Kim HS, Lee S, Kang I, Kim SS, Choe W, Ha, J. AMP kinase signaling determines whether c-Jun N-terminal kinase promotes survival or apoptosis during glucose deprivation. Carcinogenesis. 2009;30:529-37.
    • (2009) Carcinogenesis , vol.30 , pp. 529-537
    • Yun, H.1    Kim, H.S.2    Lee, S.3    Kang, I.4    Kim, S.S.5    Choe, W.6    Ha, J.7
  • 108
    • 79954729192 scopus 로고    scopus 로고
    • Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells
    • Habeeb BS, Kitayama J, Nagawa H. Adiponectin supports cell survival in glucose deprivation through enhancement of autophagic response in colorectal cancer cells. Cancer Sci. 2011;102:999-1006.
    • (2011) Cancer Sci , vol.102 , pp. 999-1006
    • Habeeb, B.S.1    Kitayama, J.2    Nagawa, H.3
  • 109
    • 79955643809 scopus 로고    scopus 로고
    • Glucose deficiency reduces collagen synthesis in breast cancer MCF7 cells
    • Cechowska-Pasko M, Kretowski R, Bankowski E. Glucose deficiency reduces collagen synthesis in breast cancer MCF7 cells. Cell Biol Int. 2011;35:141-5.
    • (2011) Cell Biol Int , vol.35 , pp. 141-145
    • Cechowska-Pasko, M.1    Kretowski, R.2    Bankowski, E.3
  • 110
  • 111
    • 1542360500 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: Actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin
    • Glister C, Kemp CF, Knight PG. Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin. Reproduction. 2004;127:239-54.
    • (2004) Reproduction , vol.127 , pp. 239-254
    • Glister, C.1    Kemp, C.F.2    Knight, P.G.3
  • 112
    • 0032191877 scopus 로고    scopus 로고
    • Follistatin: A multifunctional regulatory protein
    • Phillips DJ, de Kretser DM. Follistatin: a multifunctional regulatory protein. Front Neuroendocrinol. 1998;19:287-322.
    • (1998) Front Neuroendocrinol , vol.19 , pp. 287-322
    • Phillips, D.J.1    de Kretser, D.M.2
  • 113
    • 78449260749 scopus 로고    scopus 로고
    • Nucleolar follistatin promotes cancer cell survival under glucose-deprived conditions through inhibiting cellular rRNA synthesis
    • Gao X, Wei S, Lai K, Sheng J, Su J, Zhu J, Dong H, Hu H, Xu Z. Nucleolar follistatin promotes cancer cell survival under glucose-deprived conditions through inhibiting cellular rRNA synthesis. J Biol Chem. 2010;285:36857-64.
    • (2010) J Biol Chem , vol.285 , pp. 36857-36864
    • Gao, X.1    Wei, S.2    Lai, K.3    Sheng, J.4    Su, J.5    Zhu, J.6    Dong, H.7    Hu, H.8    Xu, Z.9
  • 114
    • 44449166220 scopus 로고    scopus 로고
    • Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase
    • Taylor RP, Parker GJ, Hazel MW, Soesanto Y, Fuller W, Yazzie MJ, McClain DA. Glucose deprivation stimulates O-GlcNAc modification of proteins through up-regulation of O-linked N-acetylglucosaminyltransferase. J Biol Chem. 2008;283:6050-7.
    • (2008) J Biol Chem , vol.283 , pp. 6050-6057
    • Taylor, R.P.1    Parker, G.J.2    Hazel, M.W.3    Soesanto, Y.4    Fuller, W.5    Yazzie, M.J.6    McClain, D.A.7
  • 116
    • 63649085232 scopus 로고    scopus 로고
    • Upregulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux
    • Taylor RP, Geisler TS, Chambers JH, McClain DA. Upregulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux. J Biol Chem. 2009;284:3425-32.
    • (2009) J Biol Chem , vol.284 , pp. 3425-3432
    • Taylor, R.P.1    Geisler, T.S.2    Chambers, J.H.3    McClain, D.A.4
  • 117
    • 79955675611 scopus 로고    scopus 로고
    • Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks
    • Kim AJ, Kim HJ, Jee HJ, Song N, Kim M, Bae YS, Chung JH, Yun J. Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks. Biochim Biophys Acta. 2011;1813:1230-8.
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 1230-1238
    • Kim, A.J.1    Kim, H.J.2    Jee, H.J.3    Song, N.4    Kim, M.5    Bae, Y.S.6    Chung, J.H.7    Yun, J.8
  • 118
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004;4:891-9.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 119
    • 0035937715 scopus 로고    scopus 로고
    • Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia
    • Chen C, Pore N, Behrooz A, Ismail-Beigi F, Maity A. Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia. J Biol Chem. 2001;276:9519-25.
    • (2001) J Biol Chem , vol.276 , pp. 9519-9525
    • Chen, C.1    Pore, N.2    Behrooz, A.3    Ismail-Beigi, F.4    Maity, A.5
  • 122
    • 33745458797 scopus 로고    scopus 로고
    • MondoA-Mlx heterodimers are candidate sensors of cellular energy status: Mitochondrial localization and direct regulation of glycolysis
    • Sans CL, Satterwhite DJ, Stoltzman CA, Breen KT, Ayer DE. MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis. Mol Cell Biol. 2006;26:4863-71.
    • (2006) Mol Cell Biol , vol.26 , pp. 4863-4871
    • Sans, C.L.1    Satterwhite, D.J.2    Stoltzman, C.A.3    Breen, K.T.4    Ayer, D.E.5
  • 123
    • 0035844297 scopus 로고    scopus 로고
    • Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes
    • O'Callaghan BL, Koo SH, Wu Y, Freake HC, Towle HC. Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytes. J Biol Chem. 2001;276:16033-9.
    • (2001) J Biol Chem , vol.276 , pp. 16033-16039
    • O'Callaghan, B.L.1    Koo, S.H.2    Wu, Y.3    Freake, H.C.4    Towle, H.C.5
  • 124
    • 0035877604 scopus 로고    scopus 로고
    • Involvement of a unique carbohydrateresponsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription
    • Rufo C, Teran-Garcia M, Nakamura MT, Koo SH, Towle HC, Clarke SD. Involvement of a unique carbohydrateresponsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription. J Biol Chem. 2001;276:21969-75.
    • (2001) J Biol Chem , vol.276 , pp. 21969-21975
    • Rufo, C.1    Teran-Garcia, M.2    Nakamura, M.T.3    Koo, S.H.4    Towle, H.C.5    Clarke, S.D.6
  • 125
    • 70349745715 scopus 로고    scopus 로고
    • Transcriptional regulation of mitochondrial glycerophosphate acyltransferase is mediated by distal promoter via ChREBP and SREBP-1
    • Guha P, Aneja KK, Shilpi RY, Haldar D. Transcriptional regulation of mitochondrial glycerophosphate acyltransferase is mediated by distal promoter via ChREBP and SREBP-1. Arch Biochem Biophys. 2009;490:85-95.
    • (2009) Arch Biochem Biophys , vol.490 , pp. 85-95
    • Guha, P.1    Aneja, K.K.2    Shilpi, R.Y.3    Haldar, D.4
  • 126
    • 69249238074 scopus 로고    scopus 로고
    • Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes
    • Iizuka K, Takeda J, Horikawa Y. Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes. FEBS Lett. 2009;583:2882-6.
    • (2009) FEBS Lett , vol.583 , pp. 2882-2886
    • Iizuka, K.1    Takeda, J.2    Horikawa, Y.3
  • 127
    • 79953886811 scopus 로고    scopus 로고
    • ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells
    • Boergesen M, Poulsen LC, Schmidt SF, Frigerio F, Maechler P, Mandrup S. ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cells. J Biol Chem. 2011;286:13214-25.
    • (2011) J Biol Chem , vol.286 , pp. 13214-13225
    • Boergesen, M.1    Poulsen, L.C.2    Schmidt, S.F.3    Frigerio, F.4    Maechler, P.5    Mandrup, S.6
  • 128
    • 77449122260 scopus 로고    scopus 로고
    • Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells
    • Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, Rutter GA, Leclerc I. Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells. Diabetes. 2010;59:153-60.
    • (2010) Diabetes , vol.59 , pp. 153-160
    • Noordeen, N.A.1    Khera, T.K.2    Sun, G.3    Longbottom, E.R.4    Pullen, T.J.5    da Silva, X.G.6    Rutter, G.A.7    Leclerc, I.8
  • 129
    • 17744367054 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis
    • Minn AH, Hafele C, Shalev A. Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis. Endocrinology. 2005;146:2397-405.
    • (2005) EndoCrinology , vol.146 , pp. 2397-2405
    • Minn, A.H.1    Hafele, C.2    Shalev, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.