AMP kinase signaling determines whether c-Jun N-terminal kinase promotes survival or apoptosis during glucose deprivation

Carcinogenesis

Volumn 30, Issue 3, 2009, Pages 529-537

  Yun, Hee ^a   Kim, Hak Su ^a   Lee, Seshin ^a   Kang, Insug ^a   Kim, Sung Soo ^a   Choe, Wonchae ^a   Ha, Joohun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE PHOSPHATE; ADENYLATE KINASE; GLUCOSE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE LKB1; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL SURVIVAL; CONTROLLED STUDY; DISORDERS OF CARBOHYDRATE METABOLISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADENYLATE KINASE; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; GLUCOSE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 62349136030     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgn259     Document Type: Article

References (45)

1. Buzzai,M. et al. (2005) The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene, 24, 4165-4173.
2. Hardie,D.G. et al. (1998) The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell? Annu. Rev. Biochem., 67, 821-855.
3. Kato,K. et al. (2002) Critical roles of AMP-activated protein kinase in constitutive tolerance of cancer cells to nutrient deprivation and tumor formation. Oncogene, 21, 6082-6090.
4. Inoki,K. et al. (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell, 115, 577-590.
5. Hawley,S.A. et al. (1996) Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J. Biol. Chem., 271, 27879-27887.
6. Hawley,S.A. et al. (2003) Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J. Biol., 2, 28.
7. Hong,S.P. et al. (2003) Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases. Proc. Natl Acad. Sci. USA, 100, 8839-8843.
8. Woods,A. et al. (2003) LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr. Biol., 13, 2004-2008.
9. Sutherland,C.M. et al. (2003) Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex. Curr. Biol., 13, 1299-1305.
10. Lizcano,J.M. et al. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J., 23, 833-843.
11. Sakamoto,K. et al. (2004) Activity of LKB1 and AMPK-related kinases in skeletal muscle: Effects of contraction, phenformin, and AICAR. Am. J. Physiol. Endocrinol. Metab., 287, E310-E317.
12. Chen,Z.P. et al. (2003) Effect of exercise intensity on skeletal muscle AMPK signaling in humans. Diabetes, 52, 2205-2212.
13. Boudeau,J. et al. (2003) LKB1, a protein kinase regulating cell proliferation and polarity. FEBS Lett., 546, 159-165.
14. Shaw,R.J. et al. (2004) The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. Proc. Natl Acad. Sci. USA, 101, 3329-3335.
15. Shaw,R.J. et al. (2004) The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell, 6, 91-99.
16. Song,J.J. et al. (2003) Effect of glucose concentration on activation of the ASK1-SEK1-JNK1 signal transduction pathway. J. Cell. Biochem., 89, 653-662.
17. Davis,R.J. (2000) Signal transduction by the JNK group of MAP kinases. Cell, 103, 239-252.
18. Xia,Z. et al. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science, 270, 1326-1331.
19. Lamb,J.A. et al. (2003) JunD mediates survival signaling by the JNK signal transduction pathway. Mol. Cell, 11, 1479-1489.
20. Abreu-Martin,M.T. et al. (1999) Fas activates the JNK pathway in human colonic epithelial cells: Lack of a direct role in apoptosis. Am. J. Physiol., 276, G599-G605.
21. Janes,K.A. et al. (2005) A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis. Science, 310, 1646-1653.
22. Yun,H. et al.. (2005) Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma. J. Biol. Chem., 280, 9963-9972.
23. Bardeesy,N. et al. (2002) Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation. Nature, 419, 162-167.
24. Laderoute,K.R. et al. (2006) 5′-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol. Cell. Biol., 26, 5336-5347.
25. Woods,A. et al. (2000) Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase. Mol. Cell. Biol., 20, 6704-6711.
26. Koh,S.H. et al. (2005) Phosphatidylinositol 3-kinase activator reduces motor neuronal cell death induced by G93A or A4V mutant SOD1 gene. Toxicology, 213, 45-55.
27. Curtin,J.F. et al. (2004) JNK regulates HIPK3 expression and promotes resistance to Fas-mediated apoptosis in DU 145 prostate carcinoma cells. J. Biol. Chem., 279, 17090-17100.
28. Choi,S.L. et al. (2001) The regulation of AMP-activated protein kinase by H(2)O(2). Biochem. Biophys. Res. Commun., 287, 92-97.
29. Torres,M. (2003) Mitogen-activated protein kinase pathways in redox signaling. Front. Biosci., 8, d369-d391.
30. Zhou,G. et al. (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest., 108, 1167-1174.
31. Rana,A. et al. (1996) The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1. J. Biol. Chem., 271, 19025-19028.
32. Song,J.J. et al. (2005) Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators. J. Biol. Chem., 280, 26845-26855.
33. Ventura,J.J. et al. (2006) Chemical genetic analysis of the time course of signal transduction by JNK. Mol. Cell, 21, 701-710.
34. Li,F. et al. (2005) Reversing chemoresistance in cisplatin-resistant human ovarian cancer cells: A role of c-Jun NH2-terminal kinase 1. Biochem. Biophys. Res. Commun., 335, 1070-1077.
35. Mansouri,A. et al. (2003) Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. J. Biol. Chem., 278, 19245-19256.
36. Roulston,A. et al. (1998) Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. J. Biol. Chem., 273, 10232-10239.
37. Ham,Y.M. et al. (2003) SEK1-dependent JNK1 activation prolongs cell survival during G-Rh2-induced apoptosis. Biochem. Biophys. Res. Commun., 304, 358-364.
38. Engedal,N. et al. (2002) C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP. Oncogene, 21, 1017-1027.
39. Sakon,S. et al. (2003) NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J., 22, 3898-3909.
40. Song,J.J. et al. (2003) Role of the ASK1-SEK1-JNK1-HIPK1 signal in Daxx trafficking and ASK1 oligomerization. J. Biol. Chem., 278 47245-47252.
41. Saitoh,M. et al. (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J., 17, 2596-2606.
42. Gotoh,Y. et al. (1998) Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J. Biol. Chem. 273, 17477-17482.
43. Urakawa,K. et al. (2000) Polyglutamation of antifolates is not required for induction of extracellular release of adenosine or expression of their anti-inflammatory effects. Immunopharmacology, 48, 137-144.
44. Weston,C.R. et al. (2002) The JNK signal transduction pathway. Curr. Opin. Genet. Dev., 12, 14-21.
45. Xia,Y. et al. (2000) MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc. Natl Acad. Sci. USA, 97 5243-5248.