Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain

Journal of Molecular Neuroscience

Volumn 46, Issue 3, 2012, Pages 554-568

  Kirshner, Michal ^a   Galron, Ronit ^a   Frenkel, Dan ^a   Mandelbaum, Gil ^a   Shiloh, Yosef ^a   Wang, Zhao Qi ^b,c   Barzilai, Ari ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Ataxia telangiectasia; Atm; DNA damage response; Dopaminergic neurons; Glial cells; Nbs1; Nigro striatal pathway; Nijmegen breakage syndrome

Indexed keywords

ATM PROTEIN; NEUROTROPHIC FACTOR; NIBRIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE COURSE; DNA DAMAGE; DNA DAMAGE RESPONSE; MOUSE; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; PROTEIN EXPRESSION; STRIATONIGRAL DEGENERATION; SUBSTANTIA NIGRA;

ANIMALS; CEREBELLUM; CORPUS STRIATUM; DNA DAMAGE; MICE; MICE, 129 STRAIN; MICE, MUTANT STRAINS; NERVE DEGENERATION; NEURODEGENERATIVE DISEASES; SUBSTANTIA NIGRA;

ATAXIA TELANGIECTASIA; MURINAE; MUS; PARKINSONIA;

EID: 84859155621     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-011-9643-y     Document Type: Article

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