메뉴 건너뛰기




Volumn 9, Issue 2, 2007, Pages 211-218

The contribution of the DNA damage response to neuronal viability

Author keywords

[No Author keywords available]

Indexed keywords

DNA; OXYGEN; REACTIVE OXYGEN METABOLITE;

EID: 33846205620     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2007.9.211     Document Type: Review
Times cited : (57)

References (64)
  • 1
    • 0032734510 scopus 로고    scopus 로고
    • DNA Strand breaks in Alzheimer's disease
    • Adamec E, Vonsattel JP, and Nixon RA. DNA Strand breaks in Alzheimer's disease. Brain Res 849: 67-77, 1999.
    • (1999) Brain Res , vol.849 , pp. 67-77
    • Adamec, E.1    Vonsattel, J.P.2    Nixon, R.A.3
  • 2
    • 0027096062 scopus 로고
    • Oxidants are a major contributor to aging
    • Ames BN and Shigenaga MK. Oxidants are a major contributor to aging. Ann NY Acad Sci 663: 85-96, 1992.
    • (1992) Ann NY Acad Sci , vol.663 , pp. 85-96
    • Ames, B.N.1    Shigenaga, M.K.2
  • 3
    • 23844433614 scopus 로고    scopus 로고
    • Molecular basis of ataxia telangiectasia and related diseases
    • Ball LG and Xiao W. Molecular basis of ataxia telangiectasia and related diseases. Acta Pharmacol Sin 26: 897-907, 2005.
    • (2005) Acta Pharmacol Sin , vol.26 , pp. 897-907
    • Ball, L.G.1    Xiao, W.2
  • 4
    • 0036012789 scopus 로고    scopus 로고
    • ATM deficiency and oxidative stress: A new dimension of defective response to DNA damage
    • Barzilai A, Rotman G, and Shiloh Y. ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage. DNA Repair (Amst) 1: 3-25, 2002.
    • (2002) DNA Repair (Amst) , vol.1 , pp. 3-25
    • Barzilai, A.1    Rotman, G.2    Shiloh, Y.3
  • 5
    • 3242886115 scopus 로고    scopus 로고
    • DNA damage responses to oxidative stress
    • Barzilai A and Yamamoto K. DNA damage responses to oxidative stress. DNA Repair (Amst) 3: 1109-1115, 2004.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1109-1115
    • Barzilai, A.1    Yamamoto, K.2
  • 6
    • 1542381057 scopus 로고    scopus 로고
    • Cell cycle regulation of neuronal apoptosis in development and disease
    • Becker EB and Bonni A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol 72: 1-25, 2004.
    • (2004) Prog Neurobiol , vol.72 , pp. 1-25
    • Becker, E.B.1    Bonni, A.2
  • 7
    • 0030956532 scopus 로고    scopus 로고
    • p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells
    • Blum D, Wu Y, Nissou MF, Arnaud S, Alim Louis B, and Verna JM. p53 and Bax activation in 6-hydroxydopamine-induced apoptosis in PC12 cells. Brain Res 751: 139-142, 1997.
    • (1997) Brain Res , vol.751 , pp. 139-142
    • Blum, D.1    Wu, Y.2    Nissou, M.F.3    Arnaud, S.4    Alim Louis, B.5    Verna, J.M.6
  • 8
    • 0020346781 scopus 로고
    • DNA hypothesis of amyotrophic lateral sclerosis
    • Bradley WG and Krasin F. DNA hypothesis of amyotrophic lateral sclerosis. Adv Neurol 36: 493-502, 1982.
    • (1982) Adv Neurol , vol.36 , pp. 493-502
    • Bradley, W.G.1    Krasin, F.2
  • 9
    • 0034941698 scopus 로고    scopus 로고
    • Role of DNA-dependent protein kinase in neuronal survival
    • Chechlacz M, Vemuri MC, and Naegele JR. Role of DNA-dependent protein kinase in neuronal survival. J Neurochem 78: 141-154, 2001.
    • (2001) J Neurochem , vol.78 , pp. 141-154
    • Chechlacz, M.1    Vemuri, M.C.2    Naegele, J.R.3
  • 11
    • 0031025997 scopus 로고    scopus 로고
    • Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G
    • Cooper PK, Nouspikel T, Clarkson SG, and Leadon SA. Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 275: 990-993, 1997.
    • (1997) Science , vol.275 , pp. 990-993
    • Cooper, P.K.1    Nouspikel, T.2    Clarkson, S.G.3    Leadon, S.A.4
  • 12
    • 18144410245 scopus 로고    scopus 로고
    • Culmsee C and Mattson MR p53 in neuronal apoptosis. Biochem Biophys Res Commun 331: 761-777, 2005.
    • Culmsee C and Mattson MR p53 in neuronal apoptosis. Biochem Biophys Res Commun 331: 761-777, 2005.
  • 13
    • 0042591268 scopus 로고    scopus 로고
    • Davydov V, Hansen LA, and Shackelford DA. Is DNA repair compromised in Alzheimer's disease? Neurobiol Aging 24: 953-968, 2003.
    • Davydov V, Hansen LA, and Shackelford DA. Is DNA repair compromised in Alzheimer's disease? Neurobiol Aging 24: 953-968, 2003.
  • 14
    • 0030831489 scopus 로고    scopus 로고
    • Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease
    • de la Monte SM, Sohn YK, and Wands JR. Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease. J Neurol Sci 152: 73-83, 1997.
    • (1997) J Neurol Sci , vol.152 , pp. 73-83
    • de la Monte, S.M.1    Sohn, Y.K.2    Wands, J.R.3
  • 16
    • 0033635191 scopus 로고    scopus 로고
    • The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease
    • Ding XL, Husseman J, Tomashevski A, Nochlin D, Jin LW, and Vincent I. The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease. Am J Pathol 157: 1983-1990, 2000.
    • (2000) Am J Pathol , vol.157 , pp. 1983-1990
    • Ding, X.L.1    Husseman, J.2    Tomashevski, A.3    Nochlin, D.4    Jin, L.W.5    Vincent, I.6
  • 17
    • 0035374588 scopus 로고    scopus 로고
    • Protein phosphatases regulate DNA-dependent protein kinase activity
    • Douglas P, Moorhead GB, Ye R, and Lees-Miller SP. Protein phosphatases regulate DNA-dependent protein kinase activity. J Biol Chem 276: 18992-18998, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 18992-18998
    • Douglas, P.1    Moorhead, G.B.2    Ye, R.3    Lees-Miller, S.P.4
  • 25
    • 0041825339 scopus 로고    scopus 로고
    • p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults
    • Gilman CP, Chan SL, Guo Z, Zhu X, Greig N, and Mattson MP. p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults. Neuromol Med 3: 159-172, 2003.
    • (2003) Neuromol Med , vol.3 , pp. 159-172
    • Gilman, C.P.1    Chan, S.L.2    Guo, Z.3    Zhu, X.4    Greig, N.5    Mattson, M.P.6
  • 26
    • 0032524070 scopus 로고    scopus 로고
    • Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
    • Herzog KH, Chong MJ, Kapsetaki M, Morgan JI, and McKinnon PJ. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 280: 1089-1091, 1998.
    • (1998) Science , vol.280 , pp. 1089-1091
    • Herzog, K.H.1    Chong, M.J.2    Kapsetaki, M.3    Morgan, J.I.4    McKinnon, P.J.5
  • 28
    • 4344622376 scopus 로고    scopus 로고
    • Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains
    • Jacobsen E, Beach T, Shen Y, Li R, and Chang Y. Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains. Brain Res Mol Brain Res 128: 1-7, 2004.
    • (2004) Brain Res Mol Brain Res , vol.128 , pp. 1-7
    • Jacobsen, E.1    Beach, T.2    Shen, Y.3    Li, R.4    Chang, Y.5
  • 29
    • 0031687793 scopus 로고    scopus 로고
    • Understanding cell death in Parkinson's disease
    • Jenner P and Olanow CW. Understanding cell death in Parkinson's disease. Ann Neurol 44: S72-84, 1998.
    • (1998) Ann Neurol , vol.44
    • Jenner, P.1    Olanow, C.W.2
  • 31
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan MB and Lim DS. The many substrates and functions of ATM. Nat Rev Mol Cell Biol 1: 179-186, 2000.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 33
    • 0030916372 scopus 로고    scopus 로고
    • Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue
    • Kisby GE, Milne J, and Sweatt C. Evidence of reduced DNA repair in amyotrophic lateral sclerosis brain tissue. Neuroreport 8: 1337-1340, 1997.
    • (1997) Neuroreport , vol.8 , pp. 1337-1340
    • Kisby, G.E.1    Milne, J.2    Sweatt, C.3
  • 35
    • 0035004122 scopus 로고    scopus 로고
    • Neuron loss during early adulthood following pre-natal low-dose X-irradiation in the mouse brain
    • Korr H, Thorsten Rohde H, Benders J, Dafotakis M, Grolms N, and Schmitz C. Neuron loss during early adulthood following pre-natal low-dose X-irradiation in the mouse brain. Int J Radiat Biol 77: 567-580, 2001.
    • (2001) Int J Radiat Biol , vol.77 , pp. 567-580
    • Korr, H.1    Thorsten Rohde, H.2    Benders, J.3    Dafotakis, M.4    Grolms, N.5    Schmitz, C.6
  • 36
    • 13244249527 scopus 로고    scopus 로고
    • Why do neurons enter the cell cycle?
    • Kruman II. Why do neurons enter the cell cycle? Cell Cycle 3: 769-773, 2004.
    • (2004) Cell Cycle , vol.3 , pp. 769-773
    • Kruman, I.I.1
  • 37
    • 1342333775 scopus 로고    scopus 로고
    • Kruman II, Wersto RP, Cardozo-Pelaez F, Smilenov L, Chan SL, Chrest FJ, Emokpae R, Jr., Gorospe M, and Mattson MP. Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron 41: 549-561, 2004.
    • Kruman II, Wersto RP, Cardozo-Pelaez F, Smilenov L, Chan SL, Chrest FJ, Emokpae R, Jr., Gorospe M, and Mattson MP. Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron 41: 549-561, 2004.
  • 38
    • 0029823454 scopus 로고    scopus 로고
    • Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice
    • LaFerla FM, Hall CK, Ngo L, and Jay G. Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice. J Clin Invest 98: 1626-1632, 1996.
    • (1996) J Clin Invest , vol.98 , pp. 1626-1632
    • LaFerla, F.M.1    Hall, C.K.2    Ngo, L.3    Jay, G.4
  • 39
    • 0034646516 scopus 로고    scopus 로고
    • Transcription-coupled repair of 8-oxoguanine: Requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome
    • Le Page F, Kwoh EE, Avrutskaya A, Gentil A, Leadon SA, Sarasin A, and Cooper PK. Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome. Cell 101: 159-171, 2000.
    • (2000) Cell , vol.101 , pp. 159-171
    • Le Page, F.1    Kwoh, E.E.2    Avrutskaya, A.3    Gentil, A.4    Leadon, S.A.5    Sarasin, A.6    Cooper, P.K.7
  • 40
    • 0034668060 scopus 로고    scopus 로고
    • Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
    • Lee Y, Barnes DE, Lindahl T, and McKinnon PJ. Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm. Genes Dev 14: 2576-2580, 2000.
    • (2000) Genes Dev , vol.14 , pp. 2576-2580
    • Lee, Y.1    Barnes, D.E.2    Lindahl, T.3    McKinnon, P.J.4
  • 41
    • 10344242914 scopus 로고    scopus 로고
    • Neurons in the cerebral cortex are most susceptible to DNA-damage in aging rat brain
    • Mandavilli BS and Rao KS. Neurons in the cerebral cortex are most susceptible to DNA-damage in aging rat brain. Biochem Mol Biol Int 40: 507-514, 1996.
    • (1996) Biochem Mol Biol Int , vol.40 , pp. 507-514
    • Mandavilli, B.S.1    Rao, K.S.2
  • 42
    • 0037083204 scopus 로고    scopus 로고
    • Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent
    • Martin LJ and Liu Z. Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent. J Neurobiol 50: 181-197, 2002.
    • (2002) J Neurobiol , vol.50 , pp. 181-197
    • Martin, L.J.1    Liu, Z.2
  • 43
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 430: 631-639, 2004.
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 44
    • 0034966837 scopus 로고    scopus 로고
    • Ataxia telangiectasia: New neurons and ATM
    • McKinnon PJ. Ataxia telangiectasia: new neurons and ATM. Trends Mol Med 7: 233-234, 2001.
    • (2001) Trends Mol Med , vol.7 , pp. 233-234
    • McKinnon, P.J.1
  • 48
    • 0032562595 scopus 로고    scopus 로고
    • In situ visualization of DNA double-strand break repair in human fibroblasts
    • Nelms BE, Maser RS, MacKay JF, Lagally MG, and Petrini JH. In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280: 590-592, 1998.
    • (1998) Science , vol.280 , pp. 590-592
    • Nelms, B.E.1    Maser, R.S.2    MacKay, J.F.3    Lagally, M.G.4    Petrini, J.H.5
  • 49
    • 0035174294 scopus 로고    scopus 로고
    • Tissue oxygen sensor function of NADPH oxidase isoforms, an unusual cytochrome aa3 and reactive oxygen species
    • Porwol T, Ehleben W, Brand V, and Acker H. Tissue oxygen sensor function of NADPH oxidase isoforms, an unusual cytochrome aa3 and reactive oxygen species. Respir Physiol 128: 331-348, 2001.
    • (2001) Respir Physiol , vol.128 , pp. 331-348
    • Porwol, T.1    Ehleben, W.2    Brand, V.3    Acker, H.4
  • 50
    • 0344443674 scopus 로고    scopus 로고
    • Characterization of perceived hyperoxia in isolated primary cardiac fibroblasts and in the reoxygenated heart
    • Roy S, Khanna S, Wallace WA, Lappalainen J, Rink C, Cardounel AJ, Zweier JL, and Sen CK. Characterization of perceived hyperoxia in isolated primary cardiac fibroblasts and in the reoxygenated heart. J Biol Chem 278: 47129-47135, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 47129-47135
    • Roy, S.1    Khanna, S.2    Wallace, W.A.3    Lappalainen, J.4    Rink, C.5    Cardounel, A.J.6    Zweier, J.L.7    Sen, C.K.8
  • 53
    • 0035812772 scopus 로고    scopus 로고
    • HIF-1, O(2), and the 3 PHDs: How animal cells signal hypoxia to the nucleus
    • Semenza GL. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 107: 1-3, 2001.
    • (2001) Cell , vol.107 , pp. 1-3
    • Semenza, G.L.1
  • 54
    • 0035092625 scopus 로고    scopus 로고
    • Antioxidant and redox regulation of cellular signaling: Introduction
    • Sen CK. Antioxidant and redox regulation of cellular signaling: introduction. Med Sci Sports Exerc 33: 368-370, 2001.
    • (2001) Med Sci Sports Exerc , vol.33 , pp. 368-370
    • Sen, C.K.1
  • 55
    • 33344463678 scopus 로고    scopus 로고
    • DNA end joining activity is reduced in Alzheimer's disease
    • Shackelford DA. DNA end joining activity is reduced in Alzheimer's disease. Neurobiol Aging 27: 596-605, 2006.
    • (2006) Neurobiol Aging , vol.27 , pp. 596-605
    • Shackelford, D.A.1
  • 57
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata M, Sasaki MS, Sonoda E, Morrison C, Hashimoto M, Utsumi H, Yamaguchi-Iwai Y, Shinohara A, and Takeda S. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J 17: 5497-5508, 1998.
    • (1998) EMBO J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6    Yamaguchi-Iwai, Y.7    Shinohara, A.8    Takeda, S.9
  • 58
    • 0023186054 scopus 로고
    • Deficient DNA repair in amyotrophic lateral sclerosis cells
    • Tandan R, Robison SH, Munzer JS, and Bradley WG. Deficient DNA repair in amyotrophic lateral sclerosis cells. J Neurol Sci 79: 189-203, 1987.
    • (1987) J Neurol Sci , vol.79 , pp. 189-203
    • Tandan, R.1    Robison, S.H.2    Munzer, J.S.3    Bradley, W.G.4
  • 59
    • 3242889151 scopus 로고    scopus 로고
    • Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis
    • Taylor AM, Groom A, and Byrd PJ. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis. DNA Repair (Amst) 3: 1219-1225, 2004.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1219-1225
    • Taylor, A.M.1    Groom, A.2    Byrd, P.J.3
  • 60
    • 23844483200 scopus 로고    scopus 로고
    • Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress
    • Thorslund T, von Kobbe C, Harrigan JA, Indig FE, Christiansen M, Stevnsner T, and Bohr VA. Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress. Mol Cell Biol 25: 7625-7636, 2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 7625-7636
    • Thorslund, T.1    von Kobbe, C.2    Harrigan, J.A.3    Indig, F.E.4    Christiansen, M.5    Stevnsner, T.6    Bohr, V.A.7
  • 61
    • 0141869885 scopus 로고    scopus 로고
    • Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress
    • Tuo J, Jaruga P, Rodriguez H, Bohr VA, and Dizdaroglu M. Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress. FASEB J 17: 668-674, 2003.
    • (2003) FASEB J , vol.17 , pp. 668-674
    • Tuo, J.1    Jaruga, P.2    Rodriguez, H.3    Bohr, V.A.4    Dizdaroglu, M.5
  • 63
    • 0035072744 scopus 로고    scopus 로고
    • Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice
    • Vemuri MC, Schiller E, and Naegele JR. Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice. Cell Death Differ 8: 245-255, 2001.
    • (2001) Cell Death Differ , vol.8 , pp. 245-255
    • Vemuri, M.C.1    Schiller, E.2    Naegele, J.R.3
  • 64
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou BB and Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 408: 433-439, 2000.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.