Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system

Experimental Neurology

Volumn 218, Issue 1, 2009, Pages 24-32

  Baranes, Koby ^a   Raz Prag, Dorit ^a   Nitzan, Anat ^a   Galron, Ronit ^a   Ashery Padan, Ruth ^a   Rotenstreich, Ygal ^a   Assaf, Yaniv ^a   Shiloh, Yosef ^a   Wang, Zhao Qi ^b,c   Barzilai, Ari ^a   Solomon, Arieh S ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Ataxia telangiectasia (A T); MRI; Myelin; Nbs1; Nijmegen breakage syndrome (NBS); Oligodentrocytes; White matter

Indexed keywords

MRE11 PROTEIN; NEUROPILIN 1; NIBRIN; RAD50 PROTEIN; SEMAPHORIN 3A;

A WAVE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B WAVE; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ELECTRORETINOGRAM; GENE DELETION; GENE DISRUPTION; GENE INACTIVATION; GENE MUTATION; GENOMIC INSTABILITY; GLIA CELL; MALE; MOUSE; MOUSE MUTANT; NERVE DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; NIJMEGEN BREAKAGE SYNDROME; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NERVE; ORTHOLOGY; PRIORITY JOURNAL; RETINA; UPREGULATION; VISUAL DISORDER; WHITE MATTER;

ALPHA-DEFENSINS; ANIMALS; CELL CYCLE PROTEINS; ELECTRORETINOGRAPHY; GENE EXPRESSION REGULATION; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MUTATION; NEURODEGENERATIVE DISEASES; NEUROGLIA; NUCLEAR PROTEINS; OPTIC NERVE; QUINOLINIUM COMPOUNDS; RETINA; RETINAL GANGLION CELLS; SEMAPHORIN-3A; VISUAL PATHWAYS;

EID: 67349181294     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.03.026     Document Type: Article

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