메뉴 건너뛰기




Volumn 3, Issue 8-9, 2004, Pages 875-882

DNA single-strand breaks and neurodegeneration

Author keywords

A T; AOA1; ataxia ocular apraxia 1; base excision repair; BER; double strand break repair; double strand breaks; DSB; DSBR; SCAN1; single strand break repair; single strand breaks; spinocerebellar ataxia with axonal neuropathy 1; SSB; SSBR; topo1; topoisomerase 1

Indexed keywords

DOUBLE STRANDED DNA; SINGLE STRANDED DNA;

EID: 3242883361     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2004.04.011     Document Type: Review
Times cited : (65)

References (84)
  • 1
    • 0035009313 scopus 로고    scopus 로고
    • Mammalian DNA single-strand break repair: An X-ra(y)ted affair
    • Caldecott K.W. Mammalian DNA single-strand break repair: an X-ra(y)ted affair. Bioessays. 23:2001;447-455
    • (2001) Bioessays , vol.23 , pp. 447-455
    • Caldecott, K.W.1
  • 2
    • 0037428228 scopus 로고    scopus 로고
    • DNA single-strand break repair and spinocerebellar ataxia
    • Caldecott K.W. DNA single-strand break repair and spinocerebellar ataxia. Cell. 112:2003;7-10
    • (2003) Cell , vol.112 , pp. 7-10
    • Caldecott, K.W.1
  • 3
    • 0041378046 scopus 로고    scopus 로고
    • XRCC1 and DNA strand break repair
    • Caldecott K.W. XRCC1 and DNA strand break repair. DNA Repair (Amst.). 2:2003;955-969
    • (2003) DNA Repair (Amst.) , vol.2 , pp. 955-969
    • Caldecott, K.W.1
  • 4
    • 0033955346 scopus 로고    scopus 로고
    • XRCC1 keeps DNA from getting stranded
    • Thompson L.H., West M.G. XRCC1 keeps DNA from getting stranded. Mutat. Res. 459:2000;1-18
    • (2000) Mutat. Res. , vol.459 , pp. 1-18
    • Thompson, L.H.1    West, M.G.2
  • 5
    • 0035209666 scopus 로고    scopus 로고
    • Detecting, signalling and repairing DNA double-strand breaks
    • Jackson S.P. Detecting, signalling and repairing DNA double-strand breaks. Biochem. Soc. Trans. 29:2001;655-661
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 655-661
    • Jackson, S.P.1
  • 6
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L., Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:2003;1542-1548
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 7
    • 0030478013 scopus 로고    scopus 로고
    • Template strand gap bypass is a general property of prokaryotic RNA polymerases: Implications for elongation mechanisms
    • Liu J., Doetsch P.W. Template strand gap bypass is a general property of prokaryotic RNA polymerases: implications for elongation mechanisms. Biochemistry. 35:1996;14999-15008
    • (1996) Biochemistry , vol.35 , pp. 14999-15008
    • Liu, J.1    Doetsch, P.W.2
  • 8
    • 0028604392 scopus 로고
    • Transcription bypass or blockage at single-strand breaks on the DNA template strand: Effect of different 3′ and 5′ flanking groups on the T7 RNA polymerase elongation complex
    • Zhou W., Doetsch P.W. Transcription bypass or blockage at single-strand breaks on the DNA template strand: effect of different 3′ and 5′ flanking groups on the T7 RNA polymerase elongation complex. Biochemistry. 33:1994;14926-14934
    • (1994) Biochemistry , vol.33 , pp. 14926-14934
    • Zhou, W.1    Doetsch, P.W.2
  • 9
    • 0029160260 scopus 로고
    • T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation
    • Zhou W., Reines D., Doetsch P.W. T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation. Cell. 82:1995;577-585
    • (1995) Cell , vol.82 , pp. 577-585
    • Zhou, W.1    Reines, D.2    Doetsch, P.W.3
  • 10
    • 0035178023 scopus 로고    scopus 로고
    • The complex clinical and genetic classification of inherited ataxias. II. Autosomal recessive ataxias
    • Di Donato S., Gellera C., Mariotti C. The complex clinical and genetic classification of inherited ataxias. II. Autosomal recessive ataxias. Neurol. Sci. 22:2001;219-228
    • (2001) Neurol. Sci. , vol.22 , pp. 219-228
    • Di Donato, S.1    Gellera, C.2    Mariotti, C.3
  • 18
    • 0036085460 scopus 로고    scopus 로고
    • Cellular roles of DNA topoisomerases: A molecular perspective
    • Wang J.C. Cellular roles of DNA topoisomerases: a molecular perspective. Nat. Rev. Mol. Cell Biol. 3:2002;430-440
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 430-440
    • Wang, J.C.1
  • 20
    • 0022340594 scopus 로고
    • Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
    • Hsiang Y.H., Hertzberg R., Hecht S., Liu L.F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem. 260:1985;14873-14878
    • (1985) J. Biol. Chem. , vol.260 , pp. 14873-14878
    • Hsiang, Y.H.1    Hertzberg, R.2    Hecht, S.3    Liu, L.F.4
  • 21
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • Hsiang Y.H., Liu L.F. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res. 48:1988;1722-1726
    • (1988) Cancer Res. , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 22
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu L.F. DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58:1989;351-375
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-375
    • Liu, L.F.1
  • 23
    • 0023807621 scopus 로고
    • Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks
    • Avemann K., Knippers R., Koller T., Sogo J.M. Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks. Mol. Cell Biol. 8:1988;3026-3034
    • (1988) Mol. Cell Biol. , vol.8 , pp. 3026-3034
    • Avemann, K.1    Knippers, R.2    Koller, T.3    Sogo, J.M.4
  • 24
    • 0024388737 scopus 로고
    • Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells
    • Holm C., Covey J.M., Kerrigan D., Pommier Y. Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells. Cancer Res. 49:1989;6365-6368
    • (1989) Cancer Res. , vol.49 , pp. 6365-6368
    • Holm, C.1    Covey, J.M.2    Kerrigan, D.3    Pommier, Y.4
  • 25
    • 0024420685 scopus 로고
    • Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • Hsiang Y.H., Lihou M.G., Liu L.F. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res. 49:1989;5077-5082
    • (1989) Cancer Res. , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 26
    • 0025812689 scopus 로고
    • Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
    • Ryan A.J., Squires S., Strutt H.L., Johnson R.T. Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res. 19:1991;3295-3300
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3295-3300
    • Ryan, A.J.1    Squires, S.2    Strutt, H.L.3    Johnson, R.T.4
  • 27
    • 0025335205 scopus 로고
    • Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription
    • Bendixen C., Thomsen B., Alsner J., Westergaard O. Camptothecin- stabilized topoisomerase I-DNA adducts cause premature termination of transcription. Biochemistry. 29:1990;5613-5619
    • (1990) Biochemistry , vol.29 , pp. 5613-5619
    • Bendixen, C.1    Thomsen, B.2    Alsner, J.3    Westergaard, O.4
  • 28
    • 0030658833 scopus 로고    scopus 로고
    • Processing of topoisomerase I cleavable complexes into DNA damage by transcription
    • Wu J., Liu L.F. Processing of topoisomerase I cleavable complexes into DNA damage by transcription. Nucleic Acids Res. 25:1997;4181-4186
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4181-4186
    • Wu, J.1    Liu, L.F.2
  • 29
    • 0024431084 scopus 로고
    • Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene
    • Kroeger P.E., Rowe T.C. Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene. Nucleic Acids Res. 17:1989;8495-8509
    • (1989) Nucleic Acids Res. , vol.17 , pp. 8495-8509
    • Kroeger, P.E.1    Rowe, T.C.2
  • 30
    • 0033569666 scopus 로고    scopus 로고
    • Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes
    • Pouliot J.J., Yao K.C., Robertson C.A., Nash H.A. Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes. Science. 286:1999;552-555
    • (1999) Science , vol.286 , pp. 552-555
    • Pouliot, J.J.1    Yao, K.C.2    Robertson, C.A.3    Nash, H.A.4
  • 31
    • 0034718482 scopus 로고    scopus 로고
    • Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]-pyrene diol epoxide adducts at the 6-amino group of adenine
    • Pommier Y., Laco G.S., Kohlhagen G., Sayer J.M., Kroth H., Jerina D.M. Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]-pyrene diol epoxide adducts at the 6-amino group of adenine. Proc. Natl. Acad. Sci. U.S.A. 97:2000;10739-10744
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 10739-10744
    • Pommier, Y.1    Laco, G.S.2    Kohlhagen, G.3    Sayer, J.M.4    Kroth, H.5    Jerina, D.M.6
  • 32
    • 0030698003 scopus 로고    scopus 로고
    • Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects
    • Pourquier P., Pilon A.A., Kohlhagen G., Mazumder A., Sharma A., Pommier Y. Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects. J. Biol. Chem. 272:1997;26441-26447
    • (1997) J. Biol. Chem. , vol.272 , pp. 26441-26447
    • Pourquier, P.1    Pilon, A.A.2    Kohlhagen, G.3    Mazumder, A.4    Sharma, A.5    Pommier, Y.6
  • 33
    • 0033605675 scopus 로고    scopus 로고
    • Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine
    • Pourquier P., Ueng L.M., Fertala J., Wang D., Park H.J., Essigmann J.M., Bjornsti M.A., Pommier Y. Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine. J. Biol. Chem. 274:1999;8516-8523
    • (1999) J. Biol. Chem. , vol.274 , pp. 8516-8523
    • Pourquier, P.1    Ueng, L.M.2    Fertala, J.3    Wang, D.4    Park, H.J.5    Essigmann, J.M.6    Bjornsti, M.A.7    Pommier, Y.8
  • 34
    • 0032711595 scopus 로고    scopus 로고
    • Mapping of eukaryotic DNA topoisomerase I catalyzed cleavage without concomitant religation in the vicinity of DNA structural anomalies
    • Christiansen K., Westergaard O. Mapping of eukaryotic DNA topoisomerase I catalyzed cleavage without concomitant religation in the vicinity of DNA structural anomalies. Biochim. Biophys. Acta. 1489:1999;249-262
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 249-262
    • Christiansen, K.1    Westergaard, O.2
  • 35
    • 0029863952 scopus 로고    scopus 로고
    • Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage
    • Lanza A., Tornaletti S., Rodolfo C., Scanavini M.C., Pedrini A.M. Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage. J. Biol. Chem. 271:1996;6978-6986
    • (1996) J. Biol. Chem. , vol.271 , pp. 6978-6986
    • Lanza, A.1    Tornaletti, S.2    Rodolfo, C.3    Scanavini, M.C.4    Pedrini, A.M.5
  • 36
    • 0031003701 scopus 로고    scopus 로고
    • Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I
    • Pourquier P., Ueng L.M., Kohlhagen G., Mazumder A., Gupta M., Kohn K.W., Pommier Y. Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I. J. Biol. Chem. 272:1997;7792-7796
    • (1997) J. Biol. Chem. , vol.272 , pp. 7792-7796
    • Pourquier, P.1    Ueng, L.M.2    Kohlhagen, G.3    Mazumder, A.4    Gupta, M.5    Kohn, K.W.6    Pommier, Y.7
  • 37
    • 0035834150 scopus 로고    scopus 로고
    • The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily
    • Interthal H., Pouliot J.J., Champoux J.J. The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily. Proc. Natl. Acad. Sci. U.S.A. 98:2001;12009-12014
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 12009-12014
    • Interthal, H.1    Pouliot, J.J.2    Champoux, J.J.3
  • 38
    • 0033569666 scopus 로고    scopus 로고
    • Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes
    • Pouliot J.J., Yao K.C., Robertson C.A., Nash H.A. Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes. Science. 286:1999;552-555
    • (1999) Science , vol.286 , pp. 552-555
    • Pouliot, J.J.1    Yao, K.C.2    Robertson, C.A.3    Nash, H.A.4
  • 39
    • 0034871092 scopus 로고    scopus 로고
    • Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae
    • Pouliot J.J., Robertson C.A., Nash H.A. Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae. Genes Cells. 6:2001;677-687
    • (2001) Genes Cells , vol.6 , pp. 677-687
    • Pouliot, J.J.1    Robertson, C.A.2    Nash, H.A.3
  • 41
    • 1242339593 scopus 로고    scopus 로고
    • Repair of DNA covalently linked to protein
    • Connelly J.C., Leach D.R. Repair of DNA covalently linked to protein. Mol. Cell. 13:2004;307-316
    • (2004) Mol. Cell , vol.13 , pp. 307-316
    • Connelly, J.C.1    Leach, D.R.2
  • 42
    • 0037178839 scopus 로고    scopus 로고
    • Conversion of phosphoglycolate to phosphate termini on 3′ overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1
    • Inamdar K.V., Pouliot J.J., Zhou T., Lees-Miller S.P., Rasouli-Nia A., Povirk L.F. Conversion of phosphoglycolate to phosphate termini on 3′ overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1. J. Biol. Chem. 277:2002;27162-27168
    • (2002) J. Biol. Chem. , vol.277 , pp. 27162-27168
    • Inamdar, K.V.1    Pouliot, J.J.2    Zhou, T.3    Lees-Miller, S.P.4    Rasouli-Nia, A.5    Povirk, L.F.6
  • 43
    • 0037108948 scopus 로고    scopus 로고
    • Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage
    • Vance J.R., Wilson T.E. Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage. Proc. Natl. Acad. Sci. U.S.A. 99:2002;13669-13674
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 13669-13674
    • Vance, J.R.1    Wilson, T.E.2
  • 44
    • 0034871092 scopus 로고    scopus 로고
    • Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae
    • Pouliot J.J., Robertson C.A., Nash H.A. Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae. Genes Cells. 6:2001;677-687
    • (2001) Genes Cells , vol.6 , pp. 677-687
    • Pouliot, J.J.1    Robertson, C.A.2    Nash, H.A.3
  • 45
    • 0025133118 scopus 로고
    • Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
    • D'Arpa P., Beardmore C., Liu L.F. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res. 50:1990;6919-6924
    • (1990) Cancer Res. , vol.50 , pp. 6919-6924
    • D'Arpa, P.1    Beardmore, C.2    Liu, L.F.3
  • 46
    • 0035853295 scopus 로고    scopus 로고
    • DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells
    • Arnaudeau C., Lundin C., Helleday T. DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells. J. Mol. Biol. 307:2001;1235-1245
    • (2001) J. Mol. Biol. , vol.307 , pp. 1235-1245
    • Arnaudeau, C.1    Lundin, C.2    Helleday, T.3
  • 47
    • 0025734557 scopus 로고
    • Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross- linking agents
    • Caldecott K., Jeggo P. Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross- linking agents. Mutat. Res. 255:1991;111-121
    • (1991) Mutat. Res. , vol.255 , pp. 111-121
    • Caldecott, K.1    Jeggo, P.2
  • 48
    • 0027752934 scopus 로고
    • Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: Phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells
    • Jones N.J., Ellard S., Waters R., Parry E.M. Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells. Carcinogenesis. 14:1993;2487-2494
    • (1993) Carcinogenesis , vol.14 , pp. 2487-2494
    • Jones, N.J.1    Ellard, S.2    Waters, R.3    Parry, E.M.4
  • 49
    • 0025134090 scopus 로고
    • DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: Comparisons to ataxia-telangiectasia cells
    • Thacker J., Ganesh A.N. DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells. Mutat. Res. 235:1990;49-58
    • (1990) Mutat. Res. , vol.235 , pp. 49-58
    • Thacker, J.1    Ganesh, A.N.2
  • 50
    • 0034683654 scopus 로고    scopus 로고
    • Evidence that camptothecin-induced aberrations in the G(2) phase of cell cycle of chinese hamster ovary (CHO) cell lines is associated with transcription, in process citation
    • Mosesso P., Pichierri P., Franchitto A., Palitti F. Evidence that camptothecin-induced aberrations in the G(2) phase of cell cycle of chinese hamster ovary (CHO) cell lines is associated with transcription, in process citation. Mutat. Res. 452:2000;189-195
    • (2000) Mutat. Res. , vol.452 , pp. 189-195
    • Mosesso, P.1    Pichierri, P.2    Franchitto, A.3    Palitti, F.4
  • 51
    • 0027393659 scopus 로고
    • Higher g2 sensitivity to the induction of chromosomal damage in the cho mutant em9 than in its parental line aa8 by camptothecin, an inhibitor of dna topoisomerase-i
    • Palitti F., Cortes F., Bassi L., Dichiara D., Fiore M., Pinero J. Higher g2 sensitivity to the induction of chromosomal damage in the cho mutant em9 than in its parental line aa8 by camptothecin, an inhibitor of dna topoisomerase-i. Mutat. Res. 285:1993;281-285
    • (1993) Mutat. Res. , vol.285 , pp. 281-285
    • Palitti, F.1    Cortes, F.2    Bassi, L.3    Dichiara, D.4    Fiore, M.5    Pinero, J.6
  • 52
    • 0031927973 scopus 로고    scopus 로고
    • The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication
    • Barrows L.R., Holden J.A., Anderson M., Darpa P. The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication. Mutat. Res.-DNA Repair. 408:1998;103-110
    • (1998) Mutat. Res.-DNA Repair , vol.408 , pp. 103-110
    • Barrows, L.R.1    Holden, J.A.2    Anderson, M.3    Darpa, P.4
  • 53
    • 0345061277 scopus 로고    scopus 로고
    • Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions
    • Plo I., Liao Z.Y., Barcelo J.M., Kohlhagen G., Caldecott K.W., Weinfeld M., Pommier Y. Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions. DNA Repair (Amst.). 2:2003;1087-1100
    • (2003) DNA Repair (Amst.) , vol.2 , pp. 1087-1100
    • Plo, I.1    Liao, Z.Y.2    Barcelo, J.M.3    Kohlhagen, G.4    Caldecott, K.W.5    Weinfeld, M.6    Pommier, Y.7
  • 54
    • 0037081269 scopus 로고    scopus 로고
    • X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance
    • Park S.Y., Lam W., Cheng Y.C. X-ray repair cross-complementing gene I protein plays an important role in camptothecin resistance. Cancer Res. 62:2002;459-465
    • (2002) Cancer Res. , vol.62 , pp. 459-465
    • Park, S.Y.1    Lam, W.2    Cheng, Y.C.3
  • 55
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • Morris E.J., Geller H.M. Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity. J. Cell Biol. 134:1996;757-770
    • (1996) J. Cell Biol. , vol.134 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 56
    • 0037347120 scopus 로고    scopus 로고
    • An age-related increase in resistance to DNA damage-induced apoptotic cell death is associated with development of DNA repair mechanisms
    • Romero A.A., Gross S.R., Cheng K.Y., Goldsmith N.K., Geller H.M. An age-related increase in resistance to DNA damage-induced apoptotic cell death is associated with development of DNA repair mechanisms. J. Neurochem. 84:2003;1275-1287
    • (2003) J. Neurochem. , vol.84 , pp. 1275-1287
    • Romero, A.A.1    Gross, S.R.2    Cheng, K.Y.3    Goldsmith, N.K.4    Geller, H.M.5
  • 58
    • 0033588161 scopus 로고    scopus 로고
    • Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3′-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage
    • Jilani A., Ramotar D., Slack C., Ong C., Yang X.M., Scherer S.W., Lasko D.D. Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3′-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage. J. Biol. Chem. 274:1999;24176-24186
    • (1999) J. Biol. Chem. , vol.274 , pp. 24176-24186
    • Jilani, A.1    Ramotar, D.2    Slack, C.3    Ong, C.4    Yang, X.M.5    Scherer, S.W.6    Lasko, D.D.7
  • 59
    • 0032189831 scopus 로고    scopus 로고
    • Repair of DNA strand gaps and nicks containing 3′-phosphate and 5′- hydroxyl termini by purified mammalian enzymes
    • Karimi-Busheri F., Lee J., Tomkinson A.E., Weinfeld M. Repair of DNA strand gaps and nicks containing 3′-phosphate and 5′- hydroxyl termini by purified mammalian enzymes. Nucleic Acids Res. 26:1998;4395-4400
    • (1998) Nucleic Acids Res. , vol.26 , pp. 4395-4400
    • Karimi-Busheri, F.1    Lee, J.2    Tomkinson, A.E.3    Weinfeld, M.4
  • 61
    • 0037040191 scopus 로고    scopus 로고
    • Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe
    • Meijer M., Karimi-Busheri F., Huang T.Y., Weinfeld M., Young D. Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by gamma-radiation or camptothecin in Schizosaccharomyces pombe. J. Biol. Chem. 277:2002;4050-4055
    • (2002) J. Biol. Chem. , vol.277 , pp. 4050-4055
    • Meijer, M.1    Karimi-Busheri, F.2    Huang, T.Y.3    Weinfeld, M.4    Young, D.5
  • 65
    • 0037162392 scopus 로고    scopus 로고
    • Hint, Fhit, and GalT: Function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases
    • Brenner C. Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases. Biochemistry. 41:2002;9003-9014
    • (2002) Biochemistry , vol.41 , pp. 9003-9014
    • Brenner, C.1
  • 68
    • 0034283878 scopus 로고    scopus 로고
    • Linking DNA damage and neurodegeneration
    • Rolig R.L., McKinnon P.J. Linking DNA damage and neurodegeneration. Trends Neurosci. 23:2000;417-424
    • (2000) Trends Neurosci. , vol.23 , pp. 417-424
    • Rolig, R.L.1    McKinnon, P.J.2
  • 69
    • 0037007152 scopus 로고    scopus 로고
    • DNA damage: Air-breaks?
    • Barnes D.E. DNA damage: air-breaks? Curr. Biol. 12:2002;R262-R264
    • (2002) Curr. Biol. , vol.12 , pp. 262-R264
    • Barnes, D.E.1
  • 70
    • 0032524070 scopus 로고    scopus 로고
    • Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
    • Herzog K.H., Chong M.J., Kapsetaki M., Morgan J.I., McKinnon P.J. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science. 280:1998;1089-1091
    • (1998) Science , vol.280 , pp. 1089-1091
    • Herzog, K.H.1    Chong, M.J.2    Kapsetaki, M.3    Morgan, J.I.4    McKinnon, P.J.5
  • 71
    • 0032585526 scopus 로고    scopus 로고
    • Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
    • Barnes D.E., Stamp G., Rosewell I., Denzel A., Lindahl T. Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr. Biol. 8:1998;1395-1398
    • (1998) Curr. Biol. , vol.8 , pp. 1395-1398
    • Barnes, D.E.1    Stamp, G.2    Rosewell, I.3    Denzel, A.4    Lindahl, T.5
  • 75
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
    • Gu H., Marth J.D., Orban P.C., Mossmann H., Rajewsky K. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting. Science. 265:1994;103-106
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossmann, H.4    Rajewsky, K.5
  • 79
    • 0034668060 scopus 로고    scopus 로고
    • Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
    • Lee Y., Barnes D.E., Lindahl T., McKinnon P.J. Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm. Genes Dev. 14:2000;2576-2580
    • (2000) Genes Dev. , vol.14 , pp. 2576-2580
    • Lee, Y.1    Barnes, D.E.2    Lindahl, T.3    McKinnon, P.J.4
  • 80
    • 0035953172 scopus 로고    scopus 로고
    • Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy
    • Liu Z., Martin L.J. Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy. J. Comp. Neurol. 432:2001;35-60
    • (2001) J. Comp. Neurol. , vol.432 , pp. 35-60
    • Liu, Z.1    Martin, L.J.2
  • 81
    • 0033973876 scopus 로고    scopus 로고
    • In situ detection of AP sites and DNA strand breaks bearing 3′-phosphate termini in ischemic mouse brain
    • Huang D., Shenoy A., Cui J., Huang W., Liu P.K. In situ detection of AP sites and DNA strand breaks bearing 3′-phosphate termini in ischemic mouse brain. FASEB J. 14:2000;407-417
    • (2000) FASEB J. , vol.14 , pp. 407-417
    • Huang, D.1    Shenoy, A.2    Cui, J.3    Huang, W.4    Liu, P.K.5
  • 82
    • 2442549621 scopus 로고    scopus 로고
    • Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death
    • Daroui P., Desai S.D., Li T.K., Liu A.A., Liu L.F. Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death. J. Biol. Chem. 279:2004;14587-14594
    • (2004) J. Biol. Chem. , vol.279 , pp. 14587-14594
    • Daroui, P.1    Desai, S.D.2    Li, T.K.3    Liu, A.A.4    Liu, L.F.5
  • 83
    • 0037022534 scopus 로고    scopus 로고
    • Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants
    • Karanjawala Z.E., Murphy N., Hinton D.R., Hsieh C.L., Lieber M.R. Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr. Biol. 12:2002;397-402
    • (2002) Curr. Biol. , vol.12 , pp. 397-402
    • Karanjawala, Z.E.1    Murphy, N.2    Hinton, D.R.3    Hsieh, C.L.4    Lieber, M.R.5
  • 84
    • 0037108948 scopus 로고    scopus 로고
    • Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage
    • Vance J.R., Wilson T.E. Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage. Proc. Natl. Acad. Sci. U.S.A. 99:2002;13669-13674
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 13669-13674
    • Vance, J.R.1    Wilson, T.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.