Alternative splicing and mutation status of CHEK2 in stage III breast cancer

Oncogene

Volumn 23, Issue 52, 2004, Pages 8535-8544

  Staalesen, Vidar ^a   Falck, Jacob ^b   Geisler, Stephanie ^c   Bartkova, Jirina ^b   Børresen Dale, Anne Lise ^d   Lukas, Jiri ^b   Lillehaug, Johan Richard ^a   Bartek, Jiri ^b   Lønning, Per Eystein ^c  

^a UNIVERSITY OF BERGEN   (Norway)

^b DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Breast cancer; CHEK2; Mutation; p53; Splicing

Indexed keywords

BRCA1 PROTEIN; CELL CYCLE PROTEIN; CHECKPOINT KINASE 2; COMPLEMENTARY DNA; ISOLEUCINE; MESSENGER RNA; PROTEIN P53; THREONINE;

ALTERNATIVE RNA SPLICING; APOPTOSIS; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER STAGING; CELL GROWTH; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DNA SEQUENCE; EXON; FAMILIAL CANCER; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; STOP CODON; TUMOR SUPPRESSOR GENE;

ALTERNATIVE SPLICING; BASE SEQUENCE; BREAST NEOPLASMS; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES;

EID: 9144232488     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207928     Document Type: Article

References (52)

1. Ahn JY, Li XH, Davis HL and Canman CE. (2002). J. Biol. Chem., 277, 19389-19395.
2. Allinen M, Huusko P, Mantyniemi S, Launonen V and Winqvist R. (2001). Br. J Cancer, 85, 209-212.
3. Bartek J, Falck J and Lukas J. (2001). Nat. Rev. Mol. Cell Biol., 2, 877-886.
4. Bartek J and Lukas J. (2003). Cancer Cell, 3, 421-429.
5. Bartel F, Pinkert D, Fiedler W, Kappler M, Wurl P, Schmidt H and Taubert H. (2004). Int. J. Oncol, 24, 143-151.
6. Bartkova J, Falck J, Rajpert-De Meyts E, Skakkebaek NE, Lukas J and Bartek J. (2001). Oncogene, 20, 5897-5902.
7. Bell DW, Varley JM, Szydlo TE, Kang DH, Wahrer DCR, Shannon KE, Lubratovich M, Verselis SJ, Isselbacher KJ, Fraumeni JF, Birch JM, Li FP, Garber JE and Haber DA. (1999). Science, 286, 2528-2531.
8. Caspari T. (2000). Curr. Biol., 10, R315-R317.
9. Chehab NH, Malikzay A, Appel M and Halazonetis TD. (2000). Genes Dev., 14, 278-288.
10. Craig A, Scott M, Burch L, Smith G, Ball K and Hupp T. (2003). EMBO Rep., 4, 787-792.
11. Dong X, Wang L, Taniguchi K, Wang X, Cunningham JM, McDonnell SK, Qian C, Marks AF, Slager SL, Peterson BJ, Smith DI, Cheville JC, Blute ML, Jacobsen SJ, Schaid DJ, Tindall DJ, Thibodeau SN and Liu W. (2003). Am. J. Hum. Genet., 72, 270-280.
12. Evdokiou A, Atkins GJ, Bouralexis S, Hay S, Raggatt LJ, Cowled PA, Graves SE, Clayer M and Findlay DM. (2001). Int. J. Oncol., 19, 625-632.
13. Falck J, Lukas C, Protopopova M, Lukas J, Selivanova G and Bartek J. (2001a). Oncogene, 20, 5503-5510.
14. Falck J, Mailand N, Syljuasen RG, Bartek J and Lukas J. (2001b). Nature, 410, 842-847.
15. Frebourg T, Ebel A, Bonaiti-Pellie C, Brugieres L, Berthet P, Bressac-De Paillerets B, Chevrier A, Chompret A, Cohen-Haguenauer O, Delattre O, Feingold J, Feunteun J, Frappaz D, Flicker JP, Gesta P, Jonveaux P, Kalifa C, Lasset C, Leheup B, Limacher JM, Longy M, Nogues C, Oppenheim D, Sommelet D, Soubrier F, Stoll C, Stoppa-Lyonnet D and Tristant H. (2001). Bull. Cancer, 88, 581-587.
16. Geisler S, Børresen-Dale A-L, Johnsen H, Aas T, Geisler J, Akslen LA, Anker G and Lønning PE. (2003). Clin. Cancer Res., 9, 5582-5588.
17. Geisler S, Lønning PE, Aas T, Johnsen H, Fluge O, Haugen DF, Lillehaug JR, Akslen LA and Borresen-Dale AL. (2001). Cancer Res., 61, 2505-2512.
18. Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ and Mak TW. (2002). Mol. Cell. Biol., 22, 6521-6532.
19. Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ and Mak TW. (2000). Science, 287, 1824-1827.
20. Hofmann WK, Miller CW, Tsukasaki K, Tavor S, Ikezoe T, Hoelzer D, Takeuchi S and Koeffler HP. (2001). Leukemia Res., 25, 333-338.
21. Hori M, Shimazaki J, Inagawa S and Itabashi M. (2000). Pathol. Int., 50, 786-792.
22. Ishimoto O, Kawahara C, Enjo K, Obinata M, Nukiwa T and Ikawa S. (2002). Cancer Res., 62, 636-641.
23. Kraus A, Neff F, Behn M, Schuermann M, Muenkel K and Schlegel J. (1999). Int. J. Cancer, 80, 930-934.
24. Lee CH and Chung JH. (2001). J. Biol. Chem., 276, 30537-30541.
25. Lee JS, Collins KM, Brown AL, Lee CH and Chung JH. (2000). Nature, 404, 201-204.
26. Lee SB, Kim SH, Bell DW, Wahrer DC, Schiripo TA, Jorczak MM, Sgroi DC, Garber JE, Li FP, Nichols KE, Varley JM, Godwin AK, Shannon KM, Harlow E and Haber DA. (2001). Cancer Res., 61, 8062-8067.
27. Lukas C, Bartkova J, Latella L, Falck J, Mailand N, Schroeder T, Sehested M, Lukas J and Bartek J. (2001). Cancer Res., 61, 4990-4993.
28. Lukas C, Falck J, Bartkova J, Bartek J and Lukas J. (2003). Nat. Cell. Biol., 5, 255-260.
29. Lønning PE. (2003). Lancet Oncol., 4, 177-185.
30. Lønning PE. (2004). Trends Mol Med., 10, 113-118.
31. Maier B, Gluba W, Bernier B, Turner T, Mohammad K, Guise T, Sutherland A, Thorner M and Scrable H. (2004). Genes Dev., 18, 306-319.
32. Matsuoka S, Huang MX and Elledge SJ. (1998). Science, 282, 1893-1897.
33. Matsuoka S, Nakagawa T, Masuda A, Haruki N, Elledge SJ and Takahashi T. (2001). Cancer Res., 61, 5362-5365.
34. Meijers-Heijboer H, van den Ouweland A, Klijn J, Wasielewski M, de Snoo A, Oldenburg R, Hollestelle A, Houben M, Crepin E, van Veghel-Plandsoen M, Elstrodt F, van Duijn C, Bartels C, Meijers C, Schutte M, McGuffog L, Thompson D, Easton D, Sodha N, Seal S, Barfoot R, Mangion J, Chang-Claude J, Eccles D, Eeles R, Evans DG, Houlston R, Murday V, Narod S, Peretz T, Peto J, Phelan C, Zhang HX, Szabo C, Devilee P, Goldgar D, Futreal PA, Nathanson KL, Weber B, Rahman N and Stratton MR. (2002). Nat. Genet., 31, 55-59.
35. Meijers-Heijboer H, Wijnen J, Vasen H, Wasielewski M, Wagner A, Hollestelle A, Elstrodt F, van den Bos R, de Snoo A, Fat GT, Brekelmans C, Jagmohan S, Franken P, Verkuijlen P, van den Ouweland A, Chapman P, Tops C, Moslein G, Burn J, Lynch H, Klijn J, Fodde R and Schutte M. (2003). Am. J. Hum. Genet., 72, 1308-1314.
36. O'Nions J, Brooks LA, Sullivan A, Bell A, Dunne B, Rozycka M, Reddy A, Tidy JA, Evans D, Farrell PJ, Evans A, Gasco M, Gusterson B and Crook T. (2001). Br. J. Cancer, 85, 1551-1556.
37. Reddy A, Yuille M, Sullivan A, Repellin C, Bell A, Tidy JA, Evans DJ, Farrell PJ, Gusterson B, Gasco M and Crook T. (2002). Br. J. Cancer, 86, 756-760.
38. Seppälä EH, Ikonen T, Mononen N, Autio V, Rokman A, Matikainen MP, Tammela TL and Schleutker J. (2003). Br. J. Cancer, 89, 1966-1970.
39. Shieh SY, Ahn J, Tamai K, Taya Y and Prives C. (2000). Genes Dev., 14, 289-300.
40. Sigalas I, Calvert AH, Anderson JJ, Neal DE and Lunec J. (1996). Nat. Med., 2, 912-917.
41. Sodha N, Bullock S, Taylor R, Mitchell G, Guertl-Lackner B, Williams RD, Bevan S, Bishop K, McGuire S, Houlston RS and Eeles RA. (2002a). Br. J. Cancer, 87, 1445-1448.
42. Sodha N, Houlston RS, Williams R, Yuille MA, Mangion J and Eeles RA. (2002b). Hum. Mutat., 19, 173-177.
43. Sodha N, Williams R, Mangion J, Bullock SL, Yuille MR and Eeles RA. (2000). Science, 289, 359.
44. Sullivan A, Yuille M, Repellin C, Reddy A, Reelfs O, Bell A, Dunne B, Gusterson BA, Osin P, Farrell PJ, Yulug I, Evans A, Ozcelik T, Gasco M and Crook T. (2002). Oncogene, 21, 1316-1324.
45. Takai H, Naka K, Okada Y, Watanabe M, Harada N, Saito S, Anderson CW, Appella E, Nakanishi M, Suzuki H, Nagashima K, Sawa H, Ikeda K and Motoyama N. (2002). EMBO J., 21, 5195-5205.
46. Theard D, Coisy M, Ducommun B, Concannon P and Darbon JM. (2001). Biochem. Biophys. Res. Commun., 289, 1199-1204.
47. Tominaga K, Morisaki H, Kaneko Y, Fujimoto A, Tanaka T, Ohtsubo M, Hirai M, Okayama H, Ikeda K and Nakanishi M. (1999). J. Biol. Chem., 274, 31463-31467.
48. Vahteristo P, Bartkova J, Eerola H, Syrjakoski K, Ojala S, Kilpivaara O, Tamminen A, Kononen J, Aittomaki K, Heikkila P, Holli K, Blomqvist C, Bartek J, Kallioniemi OP and Nevanlinna H. (2002). Am. J. Hum. Genet., 71, 432-438.
49. Wu XL, Webster SR and Chen JJ. (2001). J. Biol. Chem., 276, 2971-2974.
50. Xu XZ, Tsvetkov LA and Stern DF. (2002). Mol. Cell. Biol., 22, 4419-4432.
51. Zheng YX, Li L, Shen HB, Sturgis EM, Eicher SA, Strom SS, Spitz MR and Wei QY. (2001). Carcinogenesis, 22, 2005-2008.
52. Zhou BB and Bartek J. (2004). Nat. Rev: Cancer, 4, 216-225.