메뉴 건너뛰기




Volumn 64, Issue 4, 2012, Pages 344-356

Advances in microscopy and complementary imaging techniques to assess the fate of drugs ex vivo in respiratory drug delivery. An invited paper

Author keywords

Chemical imaging; Confocal Raman microspectroscopy; Ex vivo; In vivo; Multimodal multifunctional imaging; Non optical imaging; Optical imaging; Targeted pulmonary delivery

Indexed keywords

CHEMICAL IMAGING; CONFOCAL RAMAN MICROSPECTROSCOPY; EX-VIVO; IN VIVO; MULTI-MODAL; OPTICAL IMAGING; PULMONARY DELIVERY;

EID: 84858621131     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2011.08.004     Document Type: Review
Times cited : (32)

References (159)
  • 1
    • 0036713697 scopus 로고    scopus 로고
    • Lobe-sparing resection of multiple pulmonary metastases with a new 1318-nm Nd: YAG laser-first 100 patients
    • Rolle A., Koch R., Alpard S.K., Zwischenberger J.B. Lobe-sparing resection of multiple pulmonary metastases with a new 1318-nm Nd: YAG laser-first 100 patients. Ann. Thorac. Surg. 2002, 74:865-869.
    • (2002) Ann. Thorac. Surg. , vol.74 , pp. 865-869
    • Rolle, A.1    Koch, R.2    Alpard, S.K.3    Zwischenberger, J.B.4
  • 2
    • 0034464630 scopus 로고    scopus 로고
    • Image-guided fine needle aspiration strategies for staging of lung cancer
    • Savage C., Zwischenberger J.B. Image-guided fine needle aspiration strategies for staging of lung cancer. Clin. Lung Cancer 2000, 2:101-110.
    • (2000) Clin. Lung Cancer , vol.2 , pp. 101-110
    • Savage, C.1    Zwischenberger, J.B.2
  • 3
    • 77955117107 scopus 로고    scopus 로고
    • Formulation challenges of powders for the delivery of small molecular weight molecules as aerosols
    • Informa Healthcare, New york
    • Hickey A.J., Mansour H.M. Formulation challenges of powders for the delivery of small molecular weight molecules as aerosols. Modified-Release Drug Delivery Technology 2008, 573-602. Informa Healthcare, New york.
    • (2008) Modified-Release Drug Delivery Technology , pp. 573-602
    • Hickey, A.J.1    Mansour, H.M.2
  • 4
    • 84942315255 scopus 로고    scopus 로고
    • Delivery of drugs by the pulmonary route
    • Informa Healthcare, New York
    • Hickey A.J., Mansour H.M. Delivery of drugs by the pulmonary route. Modern Pharmaceutics 2009, 191-219. Informa Healthcare, New York.
    • (2009) Modern Pharmaceutics , pp. 191-219
    • Hickey, A.J.1    Mansour, H.M.2
  • 7
    • 84983965438 scopus 로고
    • Memoir on inventing the confocal scanning microscope
    • Minsky M. Memoir on inventing the confocal scanning microscope. Scanning 1988, 10:128-138.
    • (1988) Scanning , vol.10 , pp. 128-138
    • Minsky, M.1
  • 8
    • 70350692065 scopus 로고    scopus 로고
    • Review of biomedical optical imaging-a powerful, non-invasive, non-ionizing technology for improving in vivo diagnosis
    • Balas C. Review of biomedical optical imaging-a powerful, non-invasive, non-ionizing technology for improving in vivo diagnosis. Measure. Sci. Technol. 2009, 20:1-12.
    • (2009) Measure. Sci. Technol. , vol.20 , pp. 1-12
    • Balas, C.1
  • 10
    • 51649093566 scopus 로고    scopus 로고
    • Rapid frequency-domain FLIM spinning disk confocal microscope: lifetime resolution. image improvement and wavelet analysis
    • Buranachai C., Kamiyama D., Chiba A., Williams B., Clegg R. Rapid frequency-domain FLIM spinning disk confocal microscope: lifetime resolution. image improvement and wavelet analysis. J. Fluoresc. 2008, 18:929-942.
    • (2008) J. Fluoresc. , vol.18 , pp. 929-942
    • Buranachai, C.1    Kamiyama, D.2    Chiba, A.3    Williams, B.4    Clegg, R.5
  • 12
    • 77955613343 scopus 로고    scopus 로고
    • In vivo imaging of pulmonary alveolar proteinosis using confocal endomicroscopy
    • Salaun M., Roussel F., Hauss P., Lachkar S., Thiberville L. In vivo imaging of pulmonary alveolar proteinosis using confocal endomicroscopy. Eur. Respir. J. 2010, 36:451.
    • (2010) Eur. Respir. J. , vol.36 , pp. 451
    • Salaun, M.1    Roussel, F.2    Hauss, P.3    Lachkar, S.4    Thiberville, L.5
  • 16
    • 73949141209 scopus 로고    scopus 로고
    • Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery
    • De Koker S., Naessens T., De Geest B.G., Bogaert P., Demeester J., De Smedt S., Grooten J. Biodegradable polyelectrolyte microcapsules: antigen delivery tools with Th17 skewing activity after pulmonary delivery. J. Immunol. 2010, 184:203.
    • (2010) J. Immunol. , vol.184 , pp. 203
    • De Koker, S.1    Naessens, T.2    De Geest, B.G.3    Bogaert, P.4    Demeester, J.5    De Smedt, S.6    Grooten, J.7
  • 18
    • 59649112391 scopus 로고    scopus 로고
    • Development of highly porous large PLGA microparticles for pulmonary drug delivery
    • Yang Y., Bajaj N., Xu P., Ohn K., Tsifansky M.D., Yeo Y. Development of highly porous large PLGA microparticles for pulmonary drug delivery. Biomaterials 2009, 30:1947-1953.
    • (2009) Biomaterials , vol.30 , pp. 1947-1953
    • Yang, Y.1    Bajaj, N.2    Xu, P.3    Ohn, K.4    Tsifansky, M.D.5    Yeo, Y.6
  • 19
    • 67349137616 scopus 로고    scopus 로고
    • The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells
    • Taetz S., Nafee N., Beisner J., Piotrowska K., Baldes C., Murdter T., Huwer H., Schneider M., Schaefer U., Klotz U. The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells. Eur. J. Pharm. Biopharm. 2009, 72:358-369.
    • (2009) Eur. J. Pharm. Biopharm. , vol.72 , pp. 358-369
    • Taetz, S.1    Nafee, N.2    Beisner, J.3    Piotrowska, K.4    Baldes, C.5    Murdter, T.6    Huwer, H.7    Schneider, M.8    Schaefer, U.9    Klotz, U.10
  • 20
    • 61649125992 scopus 로고    scopus 로고
    • Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: in vivo deposition and hypoglycaemic activity after delivery to rat lungs
    • Ungaro F., d'Emmanuele di Villa Bianca R., Giovino C., Miro A., Sorrentino R., Quaglia F., La Rotonda M.I. Insulin-loaded PLGA/cyclodextrin large porous particles with improved aerosolization properties: in vivo deposition and hypoglycaemic activity after delivery to rat lungs. J. Control. Release 2009, 135:25-34.
    • (2009) J. Control. Release , vol.135 , pp. 25-34
    • Ungaro, F.1    d'Emmanuele di Villa Bianca, R.2    Giovino, C.3    Miro, A.4    Sorrentino, R.5    Quaglia, F.6    La Rotonda, M.I.7
  • 22
    • 84858614222 scopus 로고    scopus 로고
    • Highly porous large poly (lactic-co-glycolic acid) microspheres adsorbed with palmityl-acylated exendin-4 as a long-acting inhalation system for treating diabetes
    • Kim H., Park H., Lee J., Kim T.H., Lee E.S., Oh K.T., Lee K.C., Youn Y.S. Highly porous large poly (lactic-co-glycolic acid) microspheres adsorbed with palmityl-acylated exendin-4 as a long-acting inhalation system for treating diabetes. Biomaterials 2010.
    • (2010) Biomaterials
    • Kim, H.1    Park, H.2    Lee, J.3    Kim, T.H.4    Lee, E.S.5    Oh, K.T.6    Lee, K.C.7    Youn, Y.S.8
  • 24
    • 37349078621 scopus 로고    scopus 로고
    • Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats
    • Wijagkanalan W., Kawakami S., Takenaga M., Igarashi R., Yamashita F., Hashida M. Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats. J. Control. Release 2008, 125:121-130.
    • (2008) J. Control. Release , vol.125 , pp. 121-130
    • Wijagkanalan, W.1    Kawakami, S.2    Takenaga, M.3    Igarashi, R.4    Yamashita, F.5    Hashida, M.6
  • 26
    • 56649121906 scopus 로고    scopus 로고
    • In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments
    • Grosse S., Thevenot G., Aron Y., Duverger E., Abdelkarim M., Roche A.C., Monsigny M., Fajac I. In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments. J. Control. Release 2008, 132:105-112.
    • (2008) J. Control. Release , vol.132 , pp. 105-112
    • Grosse, S.1    Thevenot, G.2    Aron, Y.3    Duverger, E.4    Abdelkarim, M.5    Roche, A.C.6    Monsigny, M.7    Fajac, I.8
  • 29
    • 77955472829 scopus 로고    scopus 로고
    • Inhalable microparticles as carriers for pulmonary delivery of thymopentin-loaded solid lipid nanoparticles
    • Li Y.Z., Sun X., Gong T., Liu J., Zuo J., Zhang Z.R. Inhalable microparticles as carriers for pulmonary delivery of thymopentin-loaded solid lipid nanoparticles. Pharm. Res. 2010, 1-10.
    • (2010) Pharm. Res. , pp. 1-10
    • Li, Y.Z.1    Sun, X.2    Gong, T.3    Liu, J.4    Zuo, J.5    Zhang, Z.R.6
  • 31
    • 77952670687 scopus 로고    scopus 로고
    • Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers
    • Patlolla R.R., Chougule M., Patel A.R., Jackson T., Tata P.N.V., Singh M. Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers. J. Control. Release 2010, 144:233-241.
    • (2010) J. Control. Release , vol.144 , pp. 233-241
    • Patlolla, R.R.1    Chougule, M.2    Patel, A.R.3    Jackson, T.4    Tata, P.N.V.5    Singh, M.6
  • 32
    • 39749128360 scopus 로고    scopus 로고
    • Wheat germ agglutinin-conjugated nanoparticles for sustained cellular and lung delivery of budesonide
    • Surti N., Misra A. Wheat germ agglutinin-conjugated nanoparticles for sustained cellular and lung delivery of budesonide. Drug Deliv. 2008, 15:81-86.
    • (2008) Drug Deliv. , vol.15 , pp. 81-86
    • Surti, N.1    Misra, A.2
  • 33
    • 77952550746 scopus 로고    scopus 로고
    • Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells
    • Beisner J., Dong M., Taetz S., Nafee N., Griese E.U., Schaefer U., Lehr C.M., Klotz U., Murdter T.E. Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells. Lung Cancer 2010, 68:346-354.
    • (2010) Lung Cancer , vol.68 , pp. 346-354
    • Beisner, J.1    Dong, M.2    Taetz, S.3    Nafee, N.4    Griese, E.U.5    Schaefer, U.6    Lehr, C.M.7    Klotz, U.8    Murdter, T.E.9
  • 35
    • 77950637964 scopus 로고    scopus 로고
    • Spray-dried microparticles containing polymeric micelles encapsulating hematoporphyrin
    • Yang Y.T., Chen C.T., Yang J.C., Tsai T. Spray-dried microparticles containing polymeric micelles encapsulating hematoporphyrin. AAPS J. 2010, 12:138-146.
    • (2010) AAPS J. , vol.12 , pp. 138-146
    • Yang, Y.T.1    Chen, C.T.2    Yang, J.C.3    Tsai, T.4
  • 36
    • 84858615221 scopus 로고    scopus 로고
    • Enhancing the pulmonary absorption of a macromolecule through coupling to a phage display-derived peptide: a study in Isolated perfused rat lung
    • Morris C.J., Smith M.W., Griffiths P.C., McKeown N.B., Gumbleton M. Enhancing the pulmonary absorption of a macromolecule through coupling to a phage display-derived peptide: a study in Isolated perfused rat lung. J. Control. Release 2010.
    • (2010) J. Control. Release
    • Morris, C.J.1    Smith, M.W.2    Griffiths, P.C.3    McKeown, N.B.4    Gumbleton, M.5
  • 37
    • 37849051886 scopus 로고    scopus 로고
    • Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery
    • Amidi M., Pellikaan H.C., de Boer A.H., Crommelin D.J.A., Hennink W.E., Jiskoot W. Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery. Eur. J. Pharm. Biopharm. 2008, 68:191-200.
    • (2008) Eur. J. Pharm. Biopharm. , vol.68 , pp. 191-200
    • Amidi, M.1    Pellikaan, H.C.2    de Boer, A.H.3    Crommelin, D.J.A.4    Hennink, W.E.5    Jiskoot, W.6
  • 38
    • 0025342635 scopus 로고
    • Two-photon laser scanning fluorescence microscopy
    • Denk W., Strickler J.H., Webb W.W. Two-photon laser scanning fluorescence microscopy. Science 1990, 248:73.
    • (1990) Science , vol.248 , pp. 73
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 40
    • 84858614223 scopus 로고    scopus 로고
    • Intravital microscopy as a tool to study drug delivery in preclinical studies
    • Amornphimoltham P. Intravital microscopy as a tool to study drug delivery in preclinical studies. Adv. Drug Deliv. Rev. 2010.
    • (2010) Adv. Drug Deliv. Rev.
    • Amornphimoltham, P.1
  • 41
    • 10644237946 scopus 로고    scopus 로고
    • Two-photon microscopy of cells and tissue
    • Rubart M. Two-photon microscopy of cells and tissue. Circ. Res. 2004, 95:1154-1166.
    • (2004) Circ. Res. , vol.95 , pp. 1154-1166
    • Rubart, M.1
  • 42
    • 0025342635 scopus 로고
    • Two-photon laser scanning fluorescence microscopy
    • Denk W., Strickler J.H., Webb W.W. Two-photon laser scanning fluorescence microscopy. Science 1990, 248:73-76.
    • (1990) Science , vol.248 , pp. 73-76
    • Denk, W.1    Strickler, J.H.2    Webb, W.W.3
  • 43
    • 0242353872 scopus 로고    scopus 로고
    • Nonlinear magic: multiphoton microscopy in the biosciences
    • Zipfel W.R., Williams R.M., Webb W.W. Nonlinear magic: multiphoton microscopy in the biosciences. Nat. Biotechnol. 2003, 21:1369-1377.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 1369-1377
    • Zipfel, W.R.1    Williams, R.M.2    Webb, W.W.3
  • 44
    • 33751297263 scopus 로고    scopus 로고
    • Principles of two-photon excitation fluorescence microscopy and other nonlinear imaging approaches
    • Oheim M., Michael D.J., Geisbauer M., Madsen D., Chow R.H. Principles of two-photon excitation fluorescence microscopy and other nonlinear imaging approaches. Adv. Drug Deliv. Rev. 2006, 58:788-808.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 788-808
    • Oheim, M.1    Michael, D.J.2    Geisbauer, M.3    Madsen, D.4    Chow, R.H.5
  • 45
    • 37749053190 scopus 로고    scopus 로고
    • Microscopic imaging techniques for drug discovery
    • Bullen A. Microscopic imaging techniques for drug discovery. Nat. Rev. Drug Discov. 2008, 7:54-67.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 54-67
    • Bullen, A.1
  • 46
    • 0033747389 scopus 로고    scopus 로고
    • Multiphoton microscopy in life sciences
    • Konig K. Multiphoton microscopy in life sciences. J. Microsc. 2000, 200:83-104.
    • (2000) J. Microsc. , vol.200 , pp. 83-104
    • Konig, K.1
  • 51
    • 75249104211 scopus 로고    scopus 로고
    • Second harmonic generation imaging via nonlinear endomicroscopy
    • Bao H., Boussioutas A., Jeremy R., Russell S., Gu M. Second harmonic generation imaging via nonlinear endomicroscopy. Opt. Express 2010, 18:1255-1260.
    • (2010) Opt. Express , vol.18 , pp. 1255-1260
    • Bao, H.1    Boussioutas, A.2    Jeremy, R.3    Russell, S.4    Gu, M.5
  • 52
    • 5344259630 scopus 로고    scopus 로고
    • Nonlinear microscopy: new techniques and applications
    • Mertz J. Nonlinear microscopy: new techniques and applications. Curr. Opin. Neurobiol. 2004, 14:610-616.
    • (2004) Curr. Opin. Neurobiol. , vol.14 , pp. 610-616
    • Mertz, J.1
  • 53
    • 0242385409 scopus 로고    scopus 로고
    • Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms
    • Campagnola P.J., Loew L.M. Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms. Nat. Biotechnol. 2003, 21:1356-1360.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 1356-1360
    • Campagnola, P.J.1    Loew, L.M.2
  • 54
    • 0031667172 scopus 로고    scopus 로고
    • 3D microscopy of transparent objects using third-harmonic generation
    • Muller M., Squier I., Wilson K., Brakenhoff G. 3D microscopy of transparent objects using third-harmonic generation. J. Microsc. 1998, 191:266-274.
    • (1998) J. Microsc. , vol.191 , pp. 266-274
    • Muller, M.1    Squier, I.2    Wilson, K.3    Brakenhoff, G.4
  • 57
    • 0000221574 scopus 로고    scopus 로고
    • Laser scanning third-harmonic-generation microscopy in biology
    • Yelin D., Silberberg Y. Laser scanning third-harmonic-generation microscopy in biology. Opt. Express 1999, 5:169-175.
    • (1999) Opt. Express , vol.5 , pp. 169-175
    • Yelin, D.1    Silberberg, Y.2
  • 58
    • 56249136680 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman scattering microscopy: chemical imaging for biology and medicine
    • Evans C.L., Xie X.S. Coherent anti-Stokes Raman scattering microscopy: chemical imaging for biology and medicine. Annu. Rev. Anal. Chem. 2008, 1:883-909.
    • (2008) Annu. Rev. Anal. Chem. , vol.1 , pp. 883-909
    • Evans, C.L.1    Xie, X.S.2
  • 59
    • 57549084830 scopus 로고    scopus 로고
    • Raman spectroscopy and microscopy of individual cells and cellular components
    • Chan J., Fore S., Wachsmann Hogiu S., Huser T. Raman spectroscopy and microscopy of individual cells and cellular components. Laser Photon. Rev. 2008, 2:325-349.
    • (2008) Laser Photon. Rev. , vol.2 , pp. 325-349
    • Chan, J.1    Fore, S.2    Wachsmann Hogiu, S.3    Huser, T.4
  • 60
    • 37249077003 scopus 로고    scopus 로고
    • Raman characterization and chemical imaging of biocolloidal self-assemblies, drug delivery systems, and pulmonary inhalation aerosols: a review
    • Mansour H.M., Hickey A.J. Raman characterization and chemical imaging of biocolloidal self-assemblies, drug delivery systems, and pulmonary inhalation aerosols: a review. AAPS PharmSciTech 2007, 8:140-155.
    • (2007) AAPS PharmSciTech , vol.8 , pp. 140-155
    • Mansour, H.M.1    Hickey, A.J.2
  • 62
    • 59149084335 scopus 로고    scopus 로고
    • Chemically specific imaging of cryptosporidium oocysts using coherent anti Stokes Raman scattering (CARS) microscopy
    • Murugkar S., Evans C., Xie X., Anis H. Chemically specific imaging of cryptosporidium oocysts using coherent anti Stokes Raman scattering (CARS) microscopy. J. Microsc. 2009, 233:244-250.
    • (2009) J. Microsc. , vol.233 , pp. 244-250
    • Murugkar, S.1    Evans, C.2    Xie, X.3    Anis, H.4
  • 63
    • 23244460036 scopus 로고    scopus 로고
    • Coherent anti-Stokes Raman scattering imaging of axonal myelin in live spinal tissues
    • Wang H., Fu Y., Zickmund P., Shi R., Cheng J.X. Coherent anti-Stokes Raman scattering imaging of axonal myelin in live spinal tissues. Biophys. J. 2005, 89:581-591.
    • (2005) Biophys. J. , vol.89 , pp. 581-591
    • Wang, H.1    Fu, Y.2    Zickmund, P.3    Shi, R.4    Cheng, J.X.5
  • 64
    • 34948847552 scopus 로고    scopus 로고
    • Coherent anti stokes Raman scattering imaging of myelin degradation reveals a calcium dependent pathway in lyso PtdCho induced demyelination
    • Fu Y., Wang H., Huff T.B., Shi R., Cheng J.X. Coherent anti stokes Raman scattering imaging of myelin degradation reveals a calcium dependent pathway in lyso PtdCho induced demyelination. J. Neurosci. Res. 2007, 85:2870-2881.
    • (2007) J. Neurosci. Res. , vol.85 , pp. 2870-2881
    • Fu, Y.1    Wang, H.2    Huff, T.B.3    Shi, R.4    Cheng, J.X.5
  • 65
    • 77953485039 scopus 로고    scopus 로고
    • Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice
    • Lim R.S., Kratzer A., Barry N.P., Miyazaki-Anzai S., Miyazaki M., Mantulin W.W., Levi M., Potma E.O., Tromberg B.J. Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice. J. Lipid Res. 2010, 51:1729.
    • (2010) J. Lipid Res. , vol.51 , pp. 1729
    • Lim, R.S.1    Kratzer, A.2    Barry, N.P.3    Miyazaki-Anzai, S.4    Miyazaki, M.5    Mantulin, W.W.6    Levi, M.7    Potma, E.O.8    Tromberg, B.J.9
  • 68
    • 77955725570 scopus 로고    scopus 로고
    • Label-free discrimination of normal and pulmonary cancer tissues using multiphoton fluorescence ratiometric microscopy
    • 043706-043706-043703
    • Wang C.C., Wu R., Lin S.J., Chen Y.F., Dong C.Y. Label-free discrimination of normal and pulmonary cancer tissues using multiphoton fluorescence ratiometric microscopy. Appl. Phys. Lett. 2010, 97. 043706-043706-043703.
    • (2010) Appl. Phys. Lett. , vol.97
    • Wang, C.C.1    Wu, R.2    Lin, S.J.3    Chen, Y.F.4    Dong, C.Y.5
  • 73
    • 77954616089 scopus 로고    scopus 로고
    • Advanced nanomaterials in multimodal imaging: design, functionalization, and biomedical applications
    • Liu Z., Kiessling F., Gatjens J. Advanced nanomaterials in multimodal imaging: design, functionalization, and biomedical applications. J. Nanomater. 2010, 2010:51.
    • (2010) J. Nanomater. , vol.2010 , pp. 51
    • Liu, Z.1    Kiessling, F.2    Gatjens, J.3
  • 75
    • 0035297578 scopus 로고    scopus 로고
    • Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform
    • Bugaj J.E., Achilefu S., Dorshow R.B., Rajagopalan R. Novel fluorescent contrast agents for optical imaging of in vivo tumors based on a receptor-targeted dye-peptide conjugate platform. J. Biomed. Opt. 2001, 6:122.
    • (2001) J. Biomed. Opt. , vol.6 , pp. 122
    • Bugaj, J.E.1    Achilefu, S.2    Dorshow, R.B.3    Rajagopalan, R.4
  • 78
    • 0008380298 scopus 로고
    • Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli
    • De Wet J.R., Wood K.V., Helinski D.R., DeLuca M. Cloning of firefly luciferase cDNA and the expression of active luciferase in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 1985, 82:7870.
    • (1985) Proc. Natl. Acad. Sci. U.S.A. , vol.82 , pp. 7870
    • De Wet, J.R.1    Wood, K.V.2    Helinski, D.R.3    DeLuca, M.4
  • 79
    • 0023919786 scopus 로고
    • Firefly luciferase luminescence assays using scintillation counters for quantitation in transfected mammalian cells
    • Nguyen V.T., Morange M., Bensaude O. Firefly luciferase luminescence assays using scintillation counters for quantitation in transfected mammalian cells. Anal. Biochem. 1988, 171:404-408.
    • (1988) Anal. Biochem. , vol.171 , pp. 404-408
    • Nguyen, V.T.1    Morange, M.2    Bensaude, O.3
  • 80
    • 0034981261 scopus 로고    scopus 로고
    • In utero delivery of adeno-associated viral vectors: intraperitoneal gene transfer produces long-term expression
    • Lipshutz G.S., Gruber C.A., Cao Y., Hardy J., Contag C.H., Gaensler K.M.L. In utero delivery of adeno-associated viral vectors: intraperitoneal gene transfer produces long-term expression. Mol. Ther. 2001, 3:284-292.
    • (2001) Mol. Ther. , vol.3 , pp. 284-292
    • Lipshutz, G.S.1    Gruber, C.A.2    Cao, Y.3    Hardy, J.4    Contag, C.H.5    Gaensler, K.M.L.6
  • 81
    • 41049117394 scopus 로고    scopus 로고
    • Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation
    • Luker K.E., Luker G.D. Applications of bioluminescence imaging to antiviral research and therapy: multiple luciferase enzymes and quantitation. Antiviral Res. 2008, 78:179-187.
    • (2008) Antiviral Res. , vol.78 , pp. 179-187
    • Luker, K.E.1    Luker, G.D.2
  • 85
    • 0037438371 scopus 로고    scopus 로고
    • Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging
    • Edinger M., Cao Y.A., Verneris M.R., Bachmann M.H., Contag C.H., Negrin R.S. Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging. Blood 2003, 101:640.
    • (2003) Blood , vol.101 , pp. 640
    • Edinger, M.1    Cao, Y.A.2    Verneris, M.R.3    Bachmann, M.H.4    Contag, C.H.5    Negrin, R.S.6
  • 86
    • 43249106836 scopus 로고    scopus 로고
    • Identification of a ligand-induced transient refractory period in nuclear factor-êB signaling
    • Moss B.L., Gross S., Gammon S.T., Vinjamoori A., Piwnica-Worms D. Identification of a ligand-induced transient refractory period in nuclear factor-êB signaling. J. Biol. Chem. 2008, 283:8687.
    • (2008) J. Biol. Chem. , vol.283 , pp. 8687
    • Moss, B.L.1    Gross, S.2    Gammon, S.T.3    Vinjamoori, A.4    Piwnica-Worms, D.5
  • 87
    • 60649098297 scopus 로고    scopus 로고
    • Dual imaging of pulmonary delivery and gene expression of dry powder inhalant by fluorescence and bioluminescence
    • Mizuno T., Mohri K., Nasu S., Danjo K., Okamoto H. Dual imaging of pulmonary delivery and gene expression of dry powder inhalant by fluorescence and bioluminescence. J. Control. Release 2009, 134:149-154.
    • (2009) J. Control. Release , vol.134 , pp. 149-154
    • Mizuno, T.1    Mohri, K.2    Nasu, S.3    Danjo, K.4    Okamoto, H.5
  • 88
    • 77952670572 scopus 로고    scopus 로고
    • Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation
    • Mohri K., Okuda T., Mori A., Danjo K., Okamoto H. Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation. J. Control. Release 2010, 144:221-226.
    • (2010) J. Control. Release , vol.144 , pp. 221-226
    • Mohri, K.1    Okuda, T.2    Mori, A.3    Danjo, K.4    Okamoto, H.5
  • 90
    • 77953766334 scopus 로고    scopus 로고
    • Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance
    • Garbuzenko O.B., Saad M., Pozharov V.P., Reuhl K.R., Mainelis G., Minko T. Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance. Proc. Natl. Acad. Sci. 2010, 107:10737.
    • (2010) Proc. Natl. Acad. Sci. , vol.107 , pp. 10737
    • Garbuzenko, O.B.1    Saad, M.2    Pozharov, V.P.3    Reuhl, K.R.4    Mainelis, G.5    Minko, T.6
  • 91
    • 63649115668 scopus 로고    scopus 로고
    • Targeting of the [beta] 2-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo
    • Elfinger M., Geiger J., Hasenpusch G., Uzgun S., Sieverling N., Aneja M.K., Maucksch C., Rudolph C. Targeting of the [beta] 2-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo. J. Control. Release 2009, 135:234-241.
    • (2009) J. Control. Release , vol.135 , pp. 234-241
    • Elfinger, M.1    Geiger, J.2    Hasenpusch, G.3    Uzgun, S.4    Sieverling, N.5    Aneja, M.K.6    Maucksch, C.7    Rudolph, C.8
  • 92
    • 7444267533 scopus 로고    scopus 로고
    • Hyperpolarized xenon in NMR and MRI
    • Oros A.M., Shah N.J. Hyperpolarized xenon in NMR and MRI. Phys. Med. Biol. 2004, 49:R105.
    • (2004) Phys. Med. Biol. , vol.49
    • Oros, A.M.1    Shah, N.J.2
  • 93
    • 33745489185 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy (MRS) in the investigation of cancer at The Royal Marsden Hospital and The Institute of Cancer Research
    • Leach M. Magnetic resonance spectroscopy (MRS) in the investigation of cancer at The Royal Marsden Hospital and The Institute of Cancer Research. Phys. Med. Biol. 2006, 51:R61.
    • (2006) Phys. Med. Biol. , vol.51
    • Leach, M.1
  • 95
    • 0036333722 scopus 로고    scopus 로고
    • Magnetic intracellular labeling of mammalian cells by combining (FDA-approved) superparamagnetic iron oxide MR contrast agents and commonly used transfection agents
    • Frank J.A., Zywicke H., Jordan E., Mitchell J., Lewis B.K., Miller B., Bryant L.H., Bulte J. Magnetic intracellular labeling of mammalian cells by combining (FDA-approved) superparamagnetic iron oxide MR contrast agents and commonly used transfection agents. Acad. Radiol. 2002, 9:S484.
    • (2002) Acad. Radiol. , vol.9
    • Frank, J.A.1    Zywicke, H.2    Jordan, E.3    Mitchell, J.4    Lewis, B.K.5    Miller, B.6    Bryant, L.H.7    Bulte, J.8
  • 98
    • 0036260586 scopus 로고    scopus 로고
    • Pulmonary ventilation and perfusion scanning using hyperpolarized helium 3 MRI and arterial spin tagging in healthy normal subjects and in pulmonary embolism and orthotopic lung transplant patients
    • Lipson D.A., Roberts D.A., Hansen Flaschen J., Gentile T.R., Jones G., Thompson A., Dimitrov I.E., Palevsky H.I., Leigh J.S., Schnall M. Pulmonary ventilation and perfusion scanning using hyperpolarized helium 3 MRI and arterial spin tagging in healthy normal subjects and in pulmonary embolism and orthotopic lung transplant patients. Magn. Reson. Med. 2002, 47:1073-1076.
    • (2002) Magn. Reson. Med. , vol.47 , pp. 1073-1076
    • Lipson, D.A.1    Roberts, D.A.2    Hansen Flaschen, J.3    Gentile, T.R.4    Jones, G.5    Thompson, A.6    Dimitrov, I.E.7    Palevsky, H.I.8    Leigh, J.S.9    Schnall, M.10
  • 99
    • 0037531401 scopus 로고    scopus 로고
    • Altered clearance of gadolinium diethylenetriaminepentaacetic acid aerosol from bleomycin-injured dog lungs: initial observations
    • Suga K., Yuan Y., Ogasawara N., Tsukuda T., Matsunaga N. Altered clearance of gadolinium diethylenetriaminepentaacetic acid aerosol from bleomycin-injured dog lungs: initial observations. Am. J. Respir. Crit. Care Med. 2003, 167:1704.
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , pp. 1704
    • Suga, K.1    Yuan, Y.2    Ogasawara, N.3    Tsukuda, T.4    Matsunaga, N.5
  • 100
    • 0036557857 scopus 로고    scopus 로고
    • Assessment of regional lung ventilation in dog lungs with Gd DTPA aerosol ventilation MR imaging
    • Suga K., Ogasawara N., Tsukuda T., Matsunaga N. Assessment of regional lung ventilation in dog lungs with Gd DTPA aerosol ventilation MR imaging. Acta Radiol. 2002, 43:282-291.
    • (2002) Acta Radiol. , vol.43 , pp. 282-291
    • Suga, K.1    Ogasawara, N.2    Tsukuda, T.3    Matsunaga, N.4
  • 106
    • 60549086399 scopus 로고    scopus 로고
    • Towards quantitative PET/MRI: a review of MR-based attenuation correction techniques
    • Hofmann M., Pichler B., Scholkopf B., Beyer T. Towards quantitative PET/MRI: a review of MR-based attenuation correction techniques. Eur. J. Nucl. Med. Mol. Imaging 2009, 36:93-104.
    • (2009) Eur. J. Nucl. Med. Mol. Imaging , vol.36 , pp. 93-104
    • Hofmann, M.1    Pichler, B.2    Scholkopf, B.3    Beyer, T.4
  • 107
    • 0015622338 scopus 로고
    • Computerized transverse axial tomography
    • Ambrose J., Hounsfield G. Computerized transverse axial tomography. Br. J. Radiol. 1973, 46:148.
    • (1973) Br. J. Radiol. , vol.46 , pp. 148
    • Ambrose, J.1    Hounsfield, G.2
  • 108
    • 0035181611 scopus 로고    scopus 로고
    • Computed tomographic-pathologic correlation of gross tumor volume and clinical target volume in non-small cell lung cancer
    • Chan R., He Y., Haque A., Zwischenberger J. Computed tomographic-pathologic correlation of gross tumor volume and clinical target volume in non-small cell lung cancer. Arch. Pathol. Lab. Med. 2001, 125:1469-1472.
    • (2001) Arch. Pathol. Lab. Med. , vol.125 , pp. 1469-1472
    • Chan, R.1    He, Y.2    Haque, A.3    Zwischenberger, J.4
  • 109
    • 4544330465 scopus 로고    scopus 로고
    • Micro-computed tomography-current status and developments
    • Ritman E.L. Micro-computed tomography-current status and developments. Annu. Rev. Biomed. Eng. 2004, 6:185-208.
    • (2004) Annu. Rev. Biomed. Eng. , vol.6 , pp. 185-208
    • Ritman, E.L.1
  • 110
    • 11244304503 scopus 로고    scopus 로고
    • Micro-CT with respiratory and cardiac gating
    • Badea C., Hedlund L., Johnson G. Micro-CT with respiratory and cardiac gating. Med. Phys. 2004, 31:3324.
    • (2004) Med. Phys. , vol.31 , pp. 3324
    • Badea, C.1    Hedlund, L.2    Johnson, G.3
  • 112
    • 0037313516 scopus 로고    scopus 로고
    • Molecular imaging in drug discovery and development
    • Rudin M., Weissleder R. Molecular imaging in drug discovery and development. Nat. Rev. Drug Discov. 2003, 2:123-131.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 123-131
    • Rudin, M.1    Weissleder, R.2
  • 116
    • 0035111670 scopus 로고    scopus 로고
    • Measuring total and regional lung deposition using inhaled radiotracers
    • Dolovich M. Measuring total and regional lung deposition using inhaled radiotracers. J. Aerosol Med. 2001, 14:35-44.
    • (2001) J. Aerosol Med. , vol.14 , pp. 35-44
    • Dolovich, M.1
  • 117
    • 0029915605 scopus 로고    scopus 로고
    • Scintigraphic techniques for measuring in vivo deposition
    • Gonda I. Scintigraphic techniques for measuring in vivo deposition. J. Aerosol Med. 1996, 9:59-67.
    • (1996) J. Aerosol Med. , vol.9 , pp. 59-67
    • Gonda, I.1
  • 118
    • 0034002429 scopus 로고    scopus 로고
    • Physics and instrumentation for imaging in-vivo drug distribution
    • Singh M., Waluch V. Physics and instrumentation for imaging in-vivo drug distribution. Adv. Drug Deliv. Rev. 2000, 41:7-20.
    • (2000) Adv. Drug Deliv. Rev. , vol.41 , pp. 7-20
    • Singh, M.1    Waluch, V.2
  • 121
    • 1642325181 scopus 로고    scopus 로고
    • Molecular imaging of host-pathogen interactions in intact small animals
    • Piwnica Worms D., Schuster D.P., Garbow J.R. Molecular imaging of host-pathogen interactions in intact small animals. Cell. Microbiol. 2004, 6:319-331.
    • (2004) Cell. Microbiol. , vol.6 , pp. 319-331
    • Piwnica Worms, D.1    Schuster, D.P.2    Garbow, J.R.3
  • 122
    • 0030894649 scopus 로고    scopus 로고
    • Imaging cognition: an empirical review of PET studies with normal subjects
    • Cabeza R., Nyberg L. Imaging cognition: an empirical review of PET studies with normal subjects. J. Cogn. Neurosci. 1997, 9:1-26.
    • (1997) J. Cogn. Neurosci. , vol.9 , pp. 1-26
    • Cabeza, R.1    Nyberg, L.2
  • 123
    • 26944443535 scopus 로고    scopus 로고
    • Imaging drug delivery and drug responses in the lung
    • Dolovich M., Labiris R. Imaging drug delivery and drug responses in the lung. Am Thoracic Soc 2004, 329.
    • (2004) Am Thoracic Soc , pp. 329
    • Dolovich, M.1    Labiris, R.2
  • 124
    • 0141594955 scopus 로고    scopus 로고
    • Fluorodeoxyglucose PET scan in pulmonary sarcoidosis during treatment with inhaled and oral corticosteroids
    • Milman N., Mortensen J., Sloth C. Fluorodeoxyglucose PET scan in pulmonary sarcoidosis during treatment with inhaled and oral corticosteroids. Respiration 2000, 70:408-413.
    • (2000) Respiration , vol.70 , pp. 408-413
    • Milman, N.1    Mortensen, J.2    Sloth, C.3
  • 125
    • 0034630039 scopus 로고    scopus 로고
    • Mapping PET-measured triamcinolone acetonide (TAA) aerosol distribution into deposition by airway generation
    • Lee Z., Berridge M.S., Finlay W.H., Heald D.L. Mapping PET-measured triamcinolone acetonide (TAA) aerosol distribution into deposition by airway generation. Int. J. Pharm. 2000, 199:7-16.
    • (2000) Int. J. Pharm. , vol.199 , pp. 7-16
    • Lee, Z.1    Berridge, M.S.2    Finlay, W.H.3    Heald, D.L.4
  • 126
    • 0032993862 scopus 로고    scopus 로고
    • Deposition and disposition of [11C] zanamivir following administration as an intranasal spray evaluation with positron emission tomography
    • Bergstrom M., Cass L., Valind S., Westerberg G., Lundberg E.L., Gray S., Bye A., Langstrom B. Deposition and disposition of [11C] zanamivir following administration as an intranasal spray evaluation with positron emission tomography. Clin. Pharmacokinet. 1999, 36:33-39.
    • (1999) Clin. Pharmacokinet. , vol.36 , pp. 33-39
    • Bergstrom, M.1    Cass, L.2    Valind, S.3    Westerberg, G.4    Lundberg, E.L.5    Gray, S.6    Bye, A.7    Langstrom, B.8
  • 128
    • 0036471788 scopus 로고    scopus 로고
    • The impact of 18 FDG-PET on target and critical organs in CT-based treatment planning of patients with poorly defined non-small-cell lung carcinoma: a prospective study
    • Mah K., Caldwell C.B., Ung Y.C., Danjoux C.E., Balogh J.M., Ganguli S.N., Ehrlich L.E., Tirona R. The impact of 18 FDG-PET on target and critical organs in CT-based treatment planning of patients with poorly defined non-small-cell lung carcinoma: a prospective study. Int. J. Radiat. Oncol. Biol. Phys. 2002, 52:339-350.
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.52 , pp. 339-350
    • Mah, K.1    Caldwell, C.B.2    Ung, Y.C.3    Danjoux, C.E.4    Balogh, J.M.5    Ganguli, S.N.6    Ehrlich, L.E.7    Tirona, R.8
  • 129
    • 0033989047 scopus 로고    scopus 로고
    • PET measurements of brain glucose metabolism and blood flow in major depressive disorder: a critical review
    • Videbech P. PET measurements of brain glucose metabolism and blood flow in major depressive disorder: a critical review. Acta Psychiatr. Scand. 2000, 101:11-20.
    • (2000) Acta Psychiatr. Scand. , vol.101 , pp. 11-20
    • Videbech, P.1
  • 130
    • 0032758345 scopus 로고    scopus 로고
    • Positron emission tomography imaging in the thorax
    • Erasmus J.J., Patz E.F. Positron emission tomography imaging in the thorax. Clin. Chest Med. 1999, 20:715-724.
    • (1999) Clin. Chest Med. , vol.20 , pp. 715-724
    • Erasmus, J.J.1    Patz, E.F.2
  • 132
    • 0030970261 scopus 로고    scopus 로고
    • Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis
    • Jones H., Sriskandan S., Peters A., Pride N., Krausz T., Boobis A., Haslett C. Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis. Eur. Respir. J. 1997, 10:795.
    • (1997) Eur. Respir. J. , vol.10 , pp. 795
    • Jones, H.1    Sriskandan, S.2    Peters, A.3    Pride, N.4    Krausz, T.5    Boobis, A.6    Haslett, C.7
  • 133
    • 0029940154 scopus 로고    scopus 로고
    • Imaging allergen-invoked airway inflammation in atopic asthma with [18F]-fluorodeoxyglucose and positron emission tomography
    • Taylor I., Hayes M., O'Connor B., Jones H., Hughes J., Pride N., Hill A., O'Shaughnessy K., Rhodes C., Jones T. Imaging allergen-invoked airway inflammation in atopic asthma with [18F]-fluorodeoxyglucose and positron emission tomography. Lancet 1996, 347:937-940.
    • (1996) Lancet , vol.347 , pp. 937-940
    • Taylor, I.1    Hayes, M.2    O'Connor, B.3    Jones, H.4    Hughes, J.5    Pride, N.6    Hill, A.7    O'Shaughnessy, K.8    Rhodes, C.9    Jones, T.10
  • 134
    • 0037385508 scopus 로고    scopus 로고
    • In vivo assessment of lung inflammatory cell activity in patients with COPD and asthma
    • Jones H., Marino P., Shakur B., Morrell N. In vivo assessment of lung inflammatory cell activity in patients with COPD and asthma. Eur. Respir. J. 2003, 21:567.
    • (2003) Eur. Respir. J. , vol.21 , pp. 567
    • Jones, H.1    Marino, P.2    Shakur, B.3    Morrell, N.4
  • 136
    • 0030249455 scopus 로고    scopus 로고
    • Quantifying regional hypoxia in human tumors with positron emission tomography of ['8F] fluoromisonidazole: a pretherapy study of 37 patients
    • Rasey J., Koh W., Evans M., Peterson L., Lewellen T., Graham M., Krohn K. Quantifying regional hypoxia in human tumors with positron emission tomography of ['8F] fluoromisonidazole: a pretherapy study of 37 patients. Int. J. Radiat. Oncol. Biol. Phys. 1996, 36:417-428.
    • (1996) Int. J. Radiat. Oncol. Biol. Phys. , vol.36 , pp. 417-428
    • Rasey, J.1    Koh, W.2    Evans, M.3    Peterson, L.4    Lewellen, T.5    Graham, M.6    Krohn, K.7
  • 139
    • 0029008526 scopus 로고
    • Pulmonary studies using positron emission tomography
    • Rhodes C., Hughes J. Pulmonary studies using positron emission tomography. Eur. Respir. J. 1995, 8:1001.
    • (1995) Eur. Respir. J. , vol.8 , pp. 1001
    • Rhodes, C.1    Hughes, J.2
  • 141
    • 16644371502 scopus 로고    scopus 로고
    • Systematic review of the diagnostic accuracy of 99mTc-HMPAO-SPECT in dementia
    • Dougall N.J., Bruggink S., Ebmeier K.P. Systematic review of the diagnostic accuracy of 99mTc-HMPAO-SPECT in dementia. Am. J. Geriatr. Psych. 2004, 12:554.
    • (2004) Am. J. Geriatr. Psych. , vol.12 , pp. 554
    • Dougall, N.J.1    Bruggink, S.2    Ebmeier, K.P.3
  • 142
    • 0024393031 scopus 로고
    • Comparisons of planar and tomographic gamma scintigraphy to measure the penetration index of inhaled aerosols
    • Phipps P.R., Gonda I., Bailey D., Borham P., Bautovich G., Anderson S. Comparisons of planar and tomographic gamma scintigraphy to measure the penetration index of inhaled aerosols. Am. Rev. Respir. Dis. 1989, 139:1516.
    • (1989) Am. Rev. Respir. Dis. , vol.139 , pp. 1516
    • Phipps, P.R.1    Gonda, I.2    Bailey, D.3    Borham, P.4    Bautovich, G.5    Anderson, S.6
  • 143
    • 38849162105 scopus 로고    scopus 로고
    • Technetium-99m-hexakis-2-methoxyisobutylisonitrile scintigraphy and multidrug resistance-related protein expression in human primary lung cancer
    • Duan X.Y., Wang J.S., Liu M., Guo Y.M. Technetium-99m-hexakis-2-methoxyisobutylisonitrile scintigraphy and multidrug resistance-related protein expression in human primary lung cancer. Ann. Nucl. Med. 2008, 22:49-55.
    • (2008) Ann. Nucl. Med. , vol.22 , pp. 49-55
    • Duan, X.Y.1    Wang, J.S.2    Liu, M.3    Guo, Y.M.4
  • 144
    • 73949133713 scopus 로고    scopus 로고
    • Determinants of regional ventilation and blood flow in the lung
    • Glenny R.W. Determinants of regional ventilation and blood flow in the lung. Intensive Care Med. 2009, 35:1833-1842.
    • (2009) Intensive Care Med. , vol.35 , pp. 1833-1842
    • Glenny, R.W.1
  • 149
    • 0031791001 scopus 로고    scopus 로고
    • Attenuation correction for a combined 3D PET/CT scanner
    • Kinahan P., Townsend D., Beyer T., Sashin D. Attenuation correction for a combined 3D PET/CT scanner. Med. Phys. 1998, 25:2046.
    • (1998) Med. Phys. , vol.25 , pp. 2046
    • Kinahan, P.1    Townsend, D.2    Beyer, T.3    Sashin, D.4
  • 150
    • 78649646574 scopus 로고    scopus 로고
    • Multimodality molecular imaging of the lung
    • Chen D.L., Kinahan P.E. Multimodality molecular imaging of the lung. J. Magn. Reson. Imaging 2010, 32:1409-1420.
    • (2010) J. Magn. Reson. Imaging , vol.32 , pp. 1409-1420
    • Chen, D.L.1    Kinahan, P.E.2
  • 151
    • 40249110181 scopus 로고    scopus 로고
    • Technology Insight: advances in molecular imaging and an appraisal of PET/CT scanning
    • Weber W.A., Grosu A.L., Czernin J. Technology Insight: advances in molecular imaging and an appraisal of PET/CT scanning. Nat. Rev. Clin. Oncol. 2008, 5:160-170.
    • (2008) Nat. Rev. Clin. Oncol. , vol.5 , pp. 160-170
    • Weber, W.A.1    Grosu, A.L.2    Czernin, J.3
  • 153
    • 67649766888 scopus 로고    scopus 로고
    • Lungs of patients with acute respiratory distress syndrome show diffuse inflammation in normally aerated regions: A [18F]-fluoro-2-deoxy-D-glucose PET/CT study
    • Bellani G., Messa C., Guerra L., Spagnolli E., Foti G., Patroniti N., Fumagalli R., Musch G., Fazio F., Pesenti A. Lungs of patients with acute respiratory distress syndrome show diffuse inflammation in normally aerated regions: A [18F]-fluoro-2-deoxy-D-glucose PET/CT study. Crit. Care Med. 2009, 37:2216.
    • (2009) Crit. Care Med. , vol.37 , pp. 2216
    • Bellani, G.1    Messa, C.2    Guerra, L.3    Spagnolli, E.4    Foti, G.5    Patroniti, N.6    Fumagalli, R.7    Musch, G.8    Fazio, F.9    Pesenti, A.10
  • 155
    • 65449155208 scopus 로고    scopus 로고
    • Chemical analysis in vivo and in vitro by Raman spectroscopy-from single cells to humans
    • Wachsmann-Hogiu S., Weeks T., Huser T. Chemical analysis in vivo and in vitro by Raman spectroscopy-from single cells to humans. Curr. Opin. Biotechnol. 2009, 20:63-73.
    • (2009) Curr. Opin. Biotechnol. , vol.20 , pp. 63-73
    • Wachsmann-Hogiu, S.1    Weeks, T.2    Huser, T.3
  • 156
    • 33745686170 scopus 로고    scopus 로고
    • Studies on stress-induced changes at the subcellular level by Raman microspectroscopic mapping
    • Krafft C., Knetschke T., Funk R.H.W., Salzer R. Studies on stress-induced changes at the subcellular level by Raman microspectroscopic mapping. Anal. Chem. 2006, 78:4424-4429.
    • (2006) Anal. Chem. , vol.78 , pp. 4424-4429
    • Krafft, C.1    Knetschke, T.2    Funk, R.H.W.3    Salzer, R.4
  • 157
    • 40049092965 scopus 로고    scopus 로고
    • Raman mapping and FTIR imaging of lung tissue: congenital cystic adenomatoid malformation
    • Krafft C., Codrich D., Pelizzo G., Sergo V. Raman mapping and FTIR imaging of lung tissue: congenital cystic adenomatoid malformation. Analyst 2008, 133:361-371.
    • (2008) Analyst , vol.133 , pp. 361-371
    • Krafft, C.1    Codrich, D.2    Pelizzo, G.3    Sergo, V.4
  • 158
    • 69949156973 scopus 로고    scopus 로고
    • Comparison of connective tissue invaded by Lewis lung carcinoma to healthy connective tissue by means of micro Raman spectroscopy
    • Cluff G.M., Short M.A., Lui H., McLean D.I., Zeng H., Korbelik M., Chen M.X. Comparison of connective tissue invaded by Lewis lung carcinoma to healthy connective tissue by means of micro Raman spectroscopy. J. Raman Spectrosc. 2009, 40:1087-1090.
    • (2009) J. Raman Spectrosc. , vol.40 , pp. 1087-1090
    • Cluff, G.M.1    Short, M.A.2    Lui, H.3    McLean, D.I.4    Zeng, H.5    Korbelik, M.6    Chen, M.X.7
  • 159
    • 67349267884 scopus 로고    scopus 로고
    • Magnetic surface-enhanced Raman spectroscopic (M-SERS) dots for the identification of bronchioalveolar stem cells in normal and lung cancer mice
    • Noh M.S., Jun B.H., Kim S., Kang H., Woo M.A., Minai-Tehrani A., Kim J.E., Kim J., Park J., Lim H.T. Magnetic surface-enhanced Raman spectroscopic (M-SERS) dots for the identification of bronchioalveolar stem cells in normal and lung cancer mice. Biomaterials 2009, 30:3915-3925.
    • (2009) Biomaterials , vol.30 , pp. 3915-3925
    • Noh, M.S.1    Jun, B.H.2    Kim, S.3    Kang, H.4    Woo, M.A.5    Minai-Tehrani, A.6    Kim, J.E.7    Kim, J.8    Park, J.9    Lim, H.T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.