Applications of bioluminescence imaging to antiviral research and therapy: Multiple luciferase enzymes and quantitation

Antiviral Research

Volumn 78, Issue 3, 2008, Pages 179-187

  Luker, Kathryn E ^a   Luker, Gary D ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Antiviral therapy; Bioluminescence imaging; Fluorescence; Herpes simplex virus; Interferon; Pathogenesis; Quantitation; Reporter virus; Vaccinia virus

Indexed keywords

ANTIVIRUS AGENT; GREEN FLUORESCENT PROTEIN; INTERFERON; LUCIFERASE; LUCIFERIN;

BIOLUMINESCENCE; BIOLUMINESCENCE IMAGING; DRUG RESEARCH; FLUORESCENCE; HERPES SIMPLEX VIRUS; HUMAN; IMAGING SYSTEM; NONHUMAN; PATIENT MONITORING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVIEW; VACCINIA VIRUS; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; FLUORESCENT DYES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HERPES SIMPLEX; IMAGE INTERPRETATION, COMPUTER-ASSISTED; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; RECOMBINATION, GENETIC; VACCINIA;

ANIMALIA; SIMPLEXVIRUS; VACCINIA VIRUS;

EID: 41049117394     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2008.01.158     Document Type: Review

References (31)

1. Baggett B., Roy R., Momen S., Morgan S., Tisi L., Morse D., and Gillies R. Thermostability of firefly luciferases affects efficiency of detection by in vivo bioluminescence. Mol. Imaging 3 (2004) 324-332
2. Bhaumik S., and Gambhir S. Optical imaging of Renilla luciferase reporter gene expression in living mice. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 377-382
3. Chaudhari A., Darvas F., Bading J., Moats R., Conti P., Smith D., Cherry S., and Leahy R. Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging. Phys. Med. Biol. 50 (2005) 5421-5441
4. Contag C., Contag P., Mullins J., Spilman S., Stevenson D., and Benaron D. Photonic detection of bacterial pathogens in living hosts. Mol. Microbiol. 18 (1995) 593-603
5. Cook S., and Griffin D. Luciferase imaging of a neurotropic viral infection in intact animals. J. Virol. 77 (2003) 5333-5338
6. Giepmans B., Adams S., Ellisman M., and Tsien R. The fluorescent toolbox for assessing protein location and function. Science 312 (2006) 217-224
7. Harmache A., LeBerre M., Droineau S., Giovannini M., and Bremont M. Bioluminescence imaging of live infected salmonids reveals that the fin bases are the major portal of entry for Novirhabdovirus. J. Virol. 80 (2006) 3655-3659
8. Jansen E., Pickett P., Mackanos M., and Virostko J. Effect of optical tissue clearing on spatial resolution and sensitivity of bioluminescence imaging. J. Biomed. Opt. 11 (2006) 041119
9. Kadurugamuwa J.L., Modi K., Coquoz O., Rice B., Smith S., Contag P.R., and Purchio T. Reduction of astrogliosis by early treatment of pneumococcal meningitis measured by simultaneous imaging, in vivo, of the pathogen and host response. Infect. Immun. 73 (2005) 7836-7843
10. Leclerc G., Boockfor F., Faught W., and Frawley L. Development of a destabilized firefly luciferase enzyme for measurement of gene expression. Biotechniques 29 (2000) pp. 594-596, 598
11. Lee K., Byun S., Paik J., Lee S., Song S., Choe Y., and Kim B.T. Cell uptake and tissue distribution of radioiodine labelled d-luciferin: implications for luciferase based gene imaging. Nucl. Med. Commun. 24 (2003) 1003-1009
12. Loening A., Fenn T., Wu A., and Gambhir S. Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output. Protein Eng. Des. Sel. 19 (2006) 391-400
13. Loening A., Wu A., and Gambhir S. Red-shifted Renilla reniformis luciferase variants for imaging in living subjects. Nat. Methods 4 (2007) 641-643
14. Lu Y., Tian J., Cong W., Kuman D., and Kumar D. MicroCT-guided bioluminescence tomography based on the adaptive finite element tomographic algorithm. Conf. Proc. IEEE Eng. Med. Biol. Soc. 1 (2006) 381-384
15. Luker G., Bardill J., Prior J., Pica C., Piwnica-Worms D., and Leib D. Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice. J. Virol. 76 (2002) 12149-12161
16. Luker G., Pica C., Song J., Luker K., and Piwnica-Worms D. Imaging 26S proteasome activity and inhibition in living mice. Nat. Med. 9 (2003) 969-973
17. Luker G., Prior J., Song J., Pica C., and Leib D. Bioluminescence imaging reveals systemic dissemination of HSV-1 in the absence of interferon receptors. J. Virol. 77 (2003) 11082-11093
18. Luker K., Hutchens M., Schultz T., Pekosz A., and Luker G. Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread. Virology 341 (2005) 284-300
19. Miloud T., Henrich C., and Hammerling G. Quantitative comparison of click beetle and firefly luciferases for in vivo bioluminescence imaging. J. Biomed. Opt. 12 (2007) 054018
20. Paroo Z., Bollinger R., Braasch D., Richer E., Corey D., Antich P., and Mason R. Validating bioluminescence imaging as a high-throughput, quantitative modality for assessing tumor burden. Mol. Imaging 3 (2004) 117-124
21. Pichler A., Prior J., and Piwnica-Worms D. Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 1702-1707
22. Remy I., and Michnick S. A highly sensitive protein-protein interaction assay based on Gaussia luciferase. Nat. Methods 3 (2006) 969-971
23. Rodriguez J., Rodriguez D., Rodriguez J., McGowan E., and Esteban M. Expression of the firefly luciferase gene in vaccinia virus: a highly sensitive gene marker to follow virus dissemination in tissues of infected animals. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 1667-1671
24. Shaner N., Steinbach P., and Tsien R. A guide to choosing fluorescent proteins. Nat. Methods 2 (2005) 905-909
25. Sweeney T., Mailander V., Tucker A., Olomu A., Zhang W., Cao Y., Negrin R., and Contag C. Visualizing the kinetics of tumor-cell clearance in living animals. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 12044-12049
26. Tannous B., Kim D., Fernandex J., Weissleder R., and Breakefiled X. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol. Ther. 11 (2005) 435-443
27. Venisnik K., Olafsen T., Gambhir S., and Wu A. Fusion of Gaussia luciferase to an engineered anti-carcinoembryonic antigen (CEA) antibody for in vivo optical imaging. Mol. Imaging Biol. 9 (2007) 267-277
28. Ward B., and Moss B. Visualization of intracellular movement of vaccinia virus virions containing a green fluorescent protein-B5R membrane protein chimera. J. Virol. 75 (2001) 4802-4813
29. White P., Squirrell D., Arnoud P., Lowe C., and Murray J. Improved thermostability of the North American firefly luciferase: saturation mutagenesis at position 354. Biochem. J. 319 (1996) 343-350
30. Zhao H., Doyle T., Wong R., Cao Y., Stevenson D., Piwnica-Worms D., and Contag C. Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals. Mol. Imaging 3 (2004) 43-54
31. Zhao H., Doyle T., Coquoz O., Kalish F., Rice B., and Contag C. Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. J. Biomed. Opt. 10 (2005) 41210