-
1
-
-
12344300543
-
Spying on cancer: molecular imaging in vivo with genetically encoded reporters
-
Comprehensive review presenting an introduction to molecular imaging strategies and detailed discussion of the use of genetically encoded reporters to spatiotemporally resolve transcriptional and post-translational events in vivo.
-
Gross S., and Piwnica-Worms D. Spying on cancer: molecular imaging in vivo with genetically encoded reporters. Cancer Cell 7 (2005) 5-15. Comprehensive review presenting an introduction to molecular imaging strategies and detailed discussion of the use of genetically encoded reporters to spatiotemporally resolve transcriptional and post-translational events in vivo.
-
(2005)
Cancer Cell
, vol.7
, pp. 5-15
-
-
Gross, S.1
Piwnica-Worms, D.2
-
2
-
-
0036405345
-
Advances in in vivo bioluminescence imaging of gene expression
-
Contag C.H., and Bachmann M.H. Advances in in vivo bioluminescence imaging of gene expression. Annu Rev Biomed Eng 4 (2002) 235-260
-
(2002)
Annu Rev Biomed Eng
, vol.4
, pp. 235-260
-
-
Contag, C.H.1
Bachmann, M.H.2
-
3
-
-
29144442848
-
Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo
-
Zhao H., Doyle T.C., Coquoz O., Kalish F., Rice B.W., and Contag C.H. Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. J Biomed Opt 10 (2005) 41210
-
(2005)
J Biomed Opt
, vol.10
, pp. 41210
-
-
Zhao, H.1
Doyle, T.C.2
Coquoz, O.3
Kalish, F.4
Rice, B.W.5
Contag, C.H.6
-
4
-
-
14044250981
-
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
-
Tannous B.A., Kim D.E., Fernandez J.L., Weissleder R., and Breakefield X.O. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 11 (2005) 435-443
-
(2005)
Mol Ther
, vol.11
, pp. 435-443
-
-
Tannous, B.A.1
Kim, D.E.2
Fernandez, J.L.3
Weissleder, R.4
Breakefield, X.O.5
-
5
-
-
34547627492
-
Red-shifted Renilla reniformis luciferase variants for imaging in living subjects
-
Loening A., Wu A., and Gambhir S. Red-shifted Renilla reniformis luciferase variants for imaging in living subjects. Nat Methods 4 (2007) 641-643
-
(2007)
Nat Methods
, vol.4
, pp. 641-643
-
-
Loening, A.1
Wu, A.2
Gambhir, S.3
-
6
-
-
1242342217
-
Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine
-
Pichler A., Prior J., and Piwnica-Worms D. Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine. Proc Natl Acad Sci U S A 101 (2004) 1702-1707
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1702-1707
-
-
Pichler, A.1
Prior, J.2
Piwnica-Worms, D.3
-
7
-
-
0033612185
-
Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation
-
Tarpey M., White C., Suarez E., Richardson G., Radi R., and Freeman B. Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation. Circ Res 84 (1999) 1203-1211
-
(1999)
Circ Res
, vol.84
, pp. 1203-1211
-
-
Tarpey, M.1
White, C.2
Suarez, E.3
Richardson, G.4
Radi, R.5
Freeman, B.6
-
8
-
-
33846110366
-
Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK
-
Galkin A.V., Melnick J.S., Kim S., Hood T.L., Li N., Li L., Xia G., Steensma R., Chopiuk G., Jiang J., et al. Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK. Proc Natl Acad Sci U S A 104 (2007) 270-275
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 270-275
-
-
Galkin, A.V.1
Melnick, J.S.2
Kim, S.3
Hood, T.L.4
Li, N.5
Li, L.6
Xia, G.7
Steensma, R.8
Chopiuk, G.9
Jiang, J.10
-
9
-
-
52949139787
-
Seeding and propagation of untransformed mouse mammary cells in the lung
-
In efforts to refine our understanding of cancer metastasis, the authors utilized previously untransformed mammary cells taken from transgenic mice bearing inducible oncogenes. Upon systemic injection into recipient mice, the authors used imaging to demonstrate that mouse mammary cells can bypass transformation at the primary site and develop into metastatic pulmonary lesions upon immediate or delayed oncogene induction.
-
Podsypanina K., Du Y-CN, Jechlinger M., Beverly L.J., Hambardzumyan D., and Varmus H. Seeding and propagation of untransformed mouse mammary cells in the lung. Science 321 (2008) 1841-1844. In efforts to refine our understanding of cancer metastasis, the authors utilized previously untransformed mammary cells taken from transgenic mice bearing inducible oncogenes. Upon systemic injection into recipient mice, the authors used imaging to demonstrate that mouse mammary cells can bypass transformation at the primary site and develop into metastatic pulmonary lesions upon immediate or delayed oncogene induction.
-
(2008)
Science
, vol.321
, pp. 1841-1844
-
-
Podsypanina, K.1
Du Y-CN2
Jechlinger, M.3
Beverly, L.J.4
Hambardzumyan, D.5
Varmus, H.6
-
10
-
-
41949131865
-
Long-term in vivo imaging of human angiogenesis: critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels
-
Sanz L., Santos-Valle P., Alonso-Camino V., Salas C., Serrano A., Vicario J.L., Cuesta A.M., Compte M., Sanchez-Martin D., and Alvarez-Vallina L. Long-term in vivo imaging of human angiogenesis: critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels. Microvasc Res 75 (2008) 308-314
-
(2008)
Microvasc Res
, vol.75
, pp. 308-314
-
-
Sanz, L.1
Santos-Valle, P.2
Alonso-Camino, V.3
Salas, C.4
Serrano, A.5
Vicario, J.L.6
Cuesta, A.M.7
Compte, M.8
Sanchez-Martin, D.9
Alvarez-Vallina, L.10
-
11
-
-
34347263711
-
Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models
-
Xie X., Xia W., Li Z., Kuo H.-P., Liu Y., Li Z., Ding Q., Zhang S., Spohn B., Yang Y., et al. Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. Cancer Cell 12 (2007) 52-65
-
(2007)
Cancer Cell
, vol.12
, pp. 52-65
-
-
Xie, X.1
Xia, W.2
Li, Z.3
Kuo, H.-P.4
Liu, Y.5
Li, Z.6
Ding, Q.7
Zhang, S.8
Spohn, B.9
Yang, Y.10
-
12
-
-
36849004318
-
Real-time imaging of beta-catenin dynamics in cells and living mice
-
The authors introduced a novel dual reporter system to monitor real-time β-catenin stabilization and downstream transcription activation simultaneously. This provided a robust platform to investigate potential regulators of Wnt/ β-catenin signaling in vitro as well as in vivo.
-
Naik S., and Piwnica-Worms D. Real-time imaging of beta-catenin dynamics in cells and living mice. Proc Natl Acad Sci U S A 104 (2007) 17465-17470. The authors introduced a novel dual reporter system to monitor real-time β-catenin stabilization and downstream transcription activation simultaneously. This provided a robust platform to investigate potential regulators of Wnt/ β-catenin signaling in vitro as well as in vivo.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17465-17470
-
-
Naik, S.1
Piwnica-Worms, D.2
-
13
-
-
4344656346
-
Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals
-
Luker K.E., Smith M.C., Luker G.D., Gammon S.T., Piwnica-Worms H., and Piwnica-Worms D. Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proc Natl Acad Sci U S A 101 (2004) 12288-12293
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12288-12293
-
-
Luker, K.E.1
Smith, M.C.2
Luker, G.D.3
Gammon, S.T.4
Piwnica-Worms, H.5
Piwnica-Worms, D.6
-
14
-
-
34948822244
-
Molecular imaging of Akt kinase activity
-
Zhang L., Lee K.C., Bhojani M.S., Khan A.P., Shilman A., Holland E.C., Ross B.D., and Rehemtulla A. Molecular imaging of Akt kinase activity. Nat Med 13 (2007) 1114-1119
-
(2007)
Nat Med
, vol.13
, pp. 1114-1119
-
-
Zhang, L.1
Lee, K.C.2
Bhojani, M.S.3
Khan, A.P.4
Shilman, A.5
Holland, E.C.6
Ross, B.D.7
Rehemtulla, A.8
-
15
-
-
35348813658
-
Current state of imaging protein-protein interactions in vivo with genetically encoded reporters
-
Villalobos V., Naik S., and Piwnica-Worms D. Current state of imaging protein-protein interactions in vivo with genetically encoded reporters. Annu Rev Biomed Eng 9 (2007) 321-349
-
(2007)
Annu Rev Biomed Eng
, vol.9
, pp. 321-349
-
-
Villalobos, V.1
Naik, S.2
Piwnica-Worms, D.3
-
16
-
-
48549097355
-
Noninvasive imaging and quantification of epidermal growth factor receptor kinase activation in vivo
-
Li W., Li F., Huang Q., Frederick B., Bao S., and Li C.Y. Noninvasive imaging and quantification of epidermal growth factor receptor kinase activation in vivo. Cancer Res 68 (2008) 4990-4997
-
(2008)
Cancer Res
, vol.68
, pp. 4990-4997
-
-
Li, W.1
Li, F.2
Huang, Q.3
Frederick, B.4
Bao, S.5
Li, C.Y.6
-
17
-
-
57349140703
-
Generation of a highly-inducible Gal4 → Fluc universal reporter mouse for in vivo bioluminescence imaging
-
Pichler A., Prior J., Luker G., and Piwnica-Worms D. Generation of a highly-inducible Gal4 → Fluc universal reporter mouse for in vivo bioluminescence imaging. Proc Nat'l Acad Sci U S A 105 (2008) 15932-15937
-
(2008)
Proc Nat'l Acad Sci U S A
, vol.105
, pp. 15932-15937
-
-
Pichler, A.1
Prior, J.2
Luker, G.3
Piwnica-Worms, D.4
-
18
-
-
33947203388
-
In vivo dynamics of regulatory T-cell trafficking and survival predict effective strategies to control graft-versus-host disease following allogeneic transplantation
-
In this work, the authors demonstrated the utility of non-invasive BLI in vivo to augment or replace traditional end-point assays to study the location and activity of engrafted luciferase-positive T cells in mouse models of graft versus host disease.
-
Nguyen V.H., Zeiser R., Dasilva D.L., Chang D.S., Beilhack A., Contag C.H., and Negrin R.S. In vivo dynamics of regulatory T-cell trafficking and survival predict effective strategies to control graft-versus-host disease following allogeneic transplantation. Blood 109 (2007) 2649-2656. In this work, the authors demonstrated the utility of non-invasive BLI in vivo to augment or replace traditional end-point assays to study the location and activity of engrafted luciferase-positive T cells in mouse models of graft versus host disease.
-
(2007)
Blood
, vol.109
, pp. 2649-2656
-
-
Nguyen, V.H.1
Zeiser, R.2
Dasilva, D.L.3
Chang, D.S.4
Beilhack, A.5
Contag, C.H.6
Negrin, R.S.7
-
19
-
-
36048978718
-
Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease
-
Zeiser R., Zambricki E.A., Leveson-Gower D., Kambham N., Beilhack A., and Negrin R.S. Host-derived interleukin-18 differentially impacts regulatory and conventional T cell expansion during acute graft-versus-host disease. Biol Blood Marrow Transplant 13 (2007) 1427-1438
-
(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 1427-1438
-
-
Zeiser, R.1
Zambricki, E.A.2
Leveson-Gower, D.3
Kambham, N.4
Beilhack, A.5
Negrin, R.S.6
-
20
-
-
33847350335
-
Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease
-
Zeiser R., Nguyen V.H., Hou J.Z., Beilhack A., Zambricki E., Buess M., Contag C.H., and Negrin R.S. Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease. Blood 109 (2007) 2225-2233
-
(2007)
Blood
, vol.109
, pp. 2225-2233
-
-
Zeiser, R.1
Nguyen, V.H.2
Hou, J.Z.3
Beilhack, A.4
Zambricki, E.5
Buess, M.6
Contag, C.H.7
Negrin, R.S.8
-
21
-
-
36148965120
-
Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice
-
Nervi B., Rettig M.P., Ritchey J.K., Wang H.L., Bauer G., Walker J., Bonyhadi M.L., Berenson R.J., Prior J.L., Piwnica-Worms D., et al. Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice. Exp Hematol 35 (2007) 1823-1838
-
(2007)
Exp Hematol
, vol.35
, pp. 1823-1838
-
-
Nervi, B.1
Rettig, M.P.2
Ritchey, J.K.3
Wang, H.L.4
Bauer, G.5
Walker, J.6
Bonyhadi, M.L.7
Berenson, R.J.8
Prior, J.L.9
Piwnica-Worms, D.10
-
22
-
-
37749048081
-
Image-guided analyses reveal that non-CD4 splenocytes contribute to CD4+ T cell-mediated inflammation leading to islet destruction by altering their local function and not systemic trafficking patterns
-
Lee M.H., Lee W.H., Van Y., Contag C.H., and Liu C.P. Image-guided analyses reveal that non-CD4 splenocytes contribute to CD4+ T cell-mediated inflammation leading to islet destruction by altering their local function and not systemic trafficking patterns. Mol Imaging 6 (2007) 369-383
-
(2007)
Mol Imaging
, vol.6
, pp. 369-383
-
-
Lee, M.H.1
Lee, W.H.2
Van, Y.3
Contag, C.H.4
Liu, C.P.5
-
23
-
-
43449090696
-
Prolonging islet allograft survival using in vivo bioluminescence imaging to guide timing of antilymphocyte serum treatment of rejection
-
Chen X., Zhang X., Larson C., Xia G., and Kaufman D.B. Prolonging islet allograft survival using in vivo bioluminescence imaging to guide timing of antilymphocyte serum treatment of rejection. Transplantation 85 (2008) 1246-1252
-
(2008)
Transplantation
, vol.85
, pp. 1246-1252
-
-
Chen, X.1
Zhang, X.2
Larson, C.3
Xia, G.4
Kaufman, D.B.5
-
24
-
-
37449031290
-
Molecular imaging of NF-kappaB in prostate tissue after systemic administration of IL-1 beta
-
Vykhovanets E.V., Shukla S., MacLennan G.T., Resnick M.I., Carlsen H., Blomhoff R., and Gupta S. Molecular imaging of NF-kappaB in prostate tissue after systemic administration of IL-1 beta. Prostate 68 (2008) 34-41
-
(2008)
Prostate
, vol.68
, pp. 34-41
-
-
Vykhovanets, E.V.1
Shukla, S.2
MacLennan, G.T.3
Resnick, M.I.4
Carlsen, H.5
Blomhoff, R.6
Gupta, S.7
-
25
-
-
41149097203
-
Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation
-
Ma L., Xiang Z., Sherrill T.P., Wang L., Blackwell T.S., Williams P., Chong A., Chari R., and Yin D.P. Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation. Transplantation 85 (2008) 903-910
-
(2008)
Transplantation
, vol.85
, pp. 903-910
-
-
Ma, L.1
Xiang, Z.2
Sherrill, T.P.3
Wang, L.4
Blackwell, T.S.5
Williams, P.6
Chong, A.7
Chari, R.8
Yin, D.P.9
-
26
-
-
23144448901
-
Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
-
Gross S., and Piwnica-Worms D. Real-time imaging of ligand-induced IKK activation in intact cells and in living mice. Nat Methods 2 (2005) 607-614
-
(2005)
Nat Methods
, vol.2
, pp. 607-614
-
-
Gross, S.1
Piwnica-Worms, D.2
-
27
-
-
21344439605
-
In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs
-
Davies S.J., Smith S.J., Lim K.C., Zhang H., Purchio A.F., McKerrow J.H., and West D.B. In vivo imaging of tissue eosinophilia and eosinopoietic responses to schistosome worms and eggs. Int J Parasitol 35 (2005) 851-859
-
(2005)
Int J Parasitol
, vol.35
, pp. 851-859
-
-
Davies, S.J.1
Smith, S.J.2
Lim, K.C.3
Zhang, H.4
Purchio, A.F.5
McKerrow, J.H.6
West, D.B.7
-
28
-
-
54549086452
-
Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis
-
Disson O., Grayo S., Huillet E., Nikitas G., Langa-Vives F., Dussurget O., Ragon M., Le Monnier A., Babinet C., Cossart P., et al. Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis. Nature 455 (2008) 1114-1118
-
(2008)
Nature
, vol.455
, pp. 1114-1118
-
-
Disson, O.1
Grayo, S.2
Huillet, E.3
Nikitas, G.4
Langa-Vives, F.5
Dussurget, O.6
Ragon, M.7
Le Monnier, A.8
Babinet, C.9
Cossart, P.10
-
29
-
-
57349185974
-
Persistent gamma-herpesvirus replication and its dynamic interaction with host in vivo
-
Hwang S., Wu T.T., Tong L.M., Kim K.S., Martinez-Guzman D., Colantonio A.D., Uittenbogaart C.H., and Sun R. Persistent gamma-herpesvirus replication and its dynamic interaction with host in vivo. J Virol 82 (2008) 12498-12509
-
(2008)
J Virol
, vol.82
, pp. 12498-12509
-
-
Hwang, S.1
Wu, T.T.2
Tong, L.M.3
Kim, K.S.4
Martinez-Guzman, D.5
Colantonio, A.D.6
Uittenbogaart, C.H.7
Sun, R.8
-
30
-
-
36749067850
-
Imaging of disease dynamics during meningococcal sepsis
-
Sjolinder H., and Jonsson A.B. Imaging of disease dynamics during meningococcal sepsis. PLoS ONE 2 (2007) e241
-
(2007)
PLoS ONE
, vol.2
-
-
Sjolinder, H.1
Jonsson, A.B.2
-
31
-
-
34347358653
-
Primary involvement of pharynx and Peyer's patch in inhalational and intestinal anthrax
-
The investigators utilized bioluminescent Bacillus anthracis for real-time analysis of mouse models of inhalational, cutaneous and gastrointestinal anthrax disease. The authors demonstrated B. anthracis spore germination and establishment of infection at the initial site of inoculation in cutaneous and inhalational anthrax, as well as specific infection of Peyer's patches during the gastrointestinal form of the disease.
-
Glomski I.J., Piris-Gimenez A., Huerre M., Mock Ml, and Goossens P.L. Primary involvement of pharynx and Peyer's patch in inhalational and intestinal anthrax. PLoS Pathogens 3 (2007) 0699-0708. The investigators utilized bioluminescent Bacillus anthracis for real-time analysis of mouse models of inhalational, cutaneous and gastrointestinal anthrax disease. The authors demonstrated B. anthracis spore germination and establishment of infection at the initial site of inoculation in cutaneous and inhalational anthrax, as well as specific infection of Peyer's patches during the gastrointestinal form of the disease.
-
(2007)
PLoS Pathogens
, vol.3
, pp. 0699-0708
-
-
Glomski, I.J.1
Piris-Gimenez, A.2
Huerre, M.3
Mock Ml4
Goossens, P.L.5
-
32
-
-
46249083369
-
A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence
-
Saeij J.P., Arrizabalaga G., and Boothroyd J.C. A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence. Infect Immun 76 (2008) 2402-2410
-
(2008)
Infect Immun
, vol.76
, pp. 2402-2410
-
-
Saeij, J.P.1
Arrizabalaga, G.2
Boothroyd, J.C.3
-
33
-
-
53049104310
-
Protective effect of Toll-like receptor 4 in pulmonary vaccinia infection
-
Hutchens M.A., Luker K.E., Sonstein J., Nunez G., Curtis J.L., and Luker G.D. Protective effect of Toll-like receptor 4 in pulmonary vaccinia infection. PLoS Pathog 4 (2008) e1000153
-
(2008)
PLoS Pathog
, vol.4
-
-
Hutchens, M.A.1
Luker, K.E.2
Sonstein, J.3
Nunez, G.4
Curtis, J.L.5
Luker, G.D.6
-
34
-
-
33645239282
-
Synergistic antitumor effects of immune cell-viral biotherapy
-
Thorne S.H., Negrin R.S., and Contag C.H. Synergistic antitumor effects of immune cell-viral biotherapy. Science 311 (2006) 1780-1784
-
(2006)
Science
, vol.311
, pp. 1780-1784
-
-
Thorne, S.H.1
Negrin, R.S.2
Contag, C.H.3
-
35
-
-
33845994768
-
Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity
-
Power A.T., Wang J., Falls T.J., Paterson J.M., Parato K.A., Lichty B.D., Stojdl D.F., Forsyth P.A., Atkins H., and Bell J.C. Carrier cell-based delivery of an oncolytic virus circumvents antiviral immunity. Mol Ther 15 (2007) 123-130
-
(2007)
Mol Ther
, vol.15
, pp. 123-130
-
-
Power, A.T.1
Wang, J.2
Falls, T.J.3
Paterson, J.M.4
Parato, K.A.5
Lichty, B.D.6
Stojdl, D.F.7
Forsyth, P.A.8
Atkins, H.9
Bell, J.C.10
-
36
-
-
43749092582
-
Tumor-targeting prodrug-activating bacteria for cancer therapy
-
Cheng C.M., Lu Y.L., Chuang K.H., Hung W.C., Shiea J., Su Y.C., Kao C.H., Chen B.M., Roffler S., and Cheng T.L. Tumor-targeting prodrug-activating bacteria for cancer therapy. Cancer Gene Ther 15 (2008) 393-401
-
(2008)
Cancer Gene Ther
, vol.15
, pp. 393-401
-
-
Cheng, C.M.1
Lu, Y.L.2
Chuang, K.H.3
Hung, W.C.4
Shiea, J.5
Su, Y.C.6
Kao, C.H.7
Chen, B.M.8
Roffler, S.9
Cheng, T.L.10
-
37
-
-
34748812604
-
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease
-
Li Z., Wu J.C., Sheikh A.Y., Kraft D., Cao F., Xie X., Patel M., Gambhir S.S., Robbins R.C., Cooke J.P., et al. Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation 116 (2007) I46-54
-
(2007)
Circulation
, vol.116
-
-
Li, Z.1
Wu, J.C.2
Sheikh, A.Y.3
Kraft, D.4
Cao, F.5
Xie, X.6
Patel, M.7
Gambhir, S.S.8
Robbins, R.C.9
Cooke, J.P.10
-
38
-
-
49149122875
-
Comparison of different adult stem cell types for treatment of myocardial ischemia
-
van der Bogt K.E., Sheikh A.Y., Schrepfer S., Hoyt G., Cao F., Ransohoff K.J., Swijnenburg R.J., Pearl J., Lee A., Fischbein M., et al. Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation 118 (2008) S121-129
-
(2008)
Circulation
, vol.118
-
-
van der Bogt, K.E.1
Sheikh, A.Y.2
Schrepfer, S.3
Hoyt, G.4
Cao, F.5
Ransohoff, K.J.6
Swijnenburg, R.J.7
Pearl, J.8
Lee, A.9
Fischbein, M.10
-
39
-
-
54449091799
-
Short hairpin RNA interference therapy for ischemic heart disease
-
Huang M., Chan D.A., Jia F., Xie X., Li Z., Hoyt G., Robbins R.C., Chen X., Giaccia A.J., and Wu J.C. Short hairpin RNA interference therapy for ischemic heart disease. Circulation 118 (2008) S226-233
-
(2008)
Circulation
, vol.118
-
-
Huang, M.1
Chan, D.A.2
Jia, F.3
Xie, X.4
Li, Z.5
Hoyt, G.6
Robbins, R.C.7
Chen, X.8
Giaccia, A.J.9
Wu, J.C.10
-
40
-
-
25444533024
-
Independent circadian oscillations of Period1 in specific brain areas in vivo and in vitro
-
Abraham U., Prior J.L., Granados-Fuentes D., Piwnica-Worms D.R., and Herzog E.D. Independent circadian oscillations of Period1 in specific brain areas in vivo and in vitro. J Neuroscience 25 (2005) 8620-8626
-
(2005)
J Neuroscience
, vol.25
, pp. 8620-8626
-
-
Abraham, U.1
Prior, J.L.2
Granados-Fuentes, D.3
Piwnica-Worms, D.R.4
Herzog, E.D.5
-
41
-
-
34247516815
-
Intercellular coupling confers robustness against mutations in the SCN circadian clock network
-
To understand the molecular basis of rhythmicity, the authors used BLI to monitor a Per2-FLuc fusion reporter in the context of a variety of murine circadian genetic backgrounds. The authors demonstrated the requirements of clock genes for maintaining cellular rhythmicity as well as intercellular coupling for maintaining the clock system.
-
Liu A.C., Welsh D.K., Ko C.H., Tran H.G., Zhang E.E., Priest A.A., Buhr E.D., Singer O., Meeker K., Verma I.M., et al. Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell 129 (2007) 605-616. To understand the molecular basis of rhythmicity, the authors used BLI to monitor a Per2-FLuc fusion reporter in the context of a variety of murine circadian genetic backgrounds. The authors demonstrated the requirements of clock genes for maintaining cellular rhythmicity as well as intercellular coupling for maintaining the clock system.
-
(2007)
Cell
, vol.129
, pp. 605-616
-
-
Liu, A.C.1
Welsh, D.K.2
Ko, C.H.3
Tran, H.G.4
Zhang, E.E.5
Priest, A.A.6
Buhr, E.D.7
Singer, O.8
Meeker, K.9
Verma, I.M.10
-
42
-
-
33845287590
-
Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration
-
Luo J., Lin A.H., Masliah E., and Wyss-Coray T. Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proc Natl Acad Sci U S A 103 (2006) 18326-18331
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18326-18331
-
-
Luo, J.1
Lin, A.H.2
Masliah, E.3
Wyss-Coray, T.4
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