PET measurements of brain glucose metabolism and blood flow in major depressive disorder: A critical review

Acta Psychiatrica Scandinavica

Volumn 101, Issue 1, 2000, Pages 11-20

  Videbech, P ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Depression; Frontal lobe; Limbic system; PET; Positron emission tomography; RCBF

Indexed keywords

ANTIDEPRESSANT AGENT; FLUORODEOXYGLUCOSE; GLUCOSE;

BRAIN BLOOD FLOW; CONTROLLED STUDY; DEPRESSION; DISEASE SEVERITY; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW;

BASAL GANGLIA; BIPOLAR DISORDER; BRAIN; DEPRESSIVE DISORDER; FEMALE; GLUCOSE; GYRUS CINGULI; HUMANS; LIMBIC SYSTEM; MALE; PREFRONTAL CORTEX; REGIONAL BLOOD FLOW; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0033989047     PISSN: 0001690X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0447.2000.101001011.x     Document Type: Review

References (76)

1. 1. Winokur G. All roads lead to depression: clinically homogeneous, etiologically heterogeneous. J Affect Disord 1997; 45:97 108.
2. 2. Charney DS. Monoamine dysfunction and the pathophysiology and treatment of depression. J Clin Psychiatry 1998;59(Suppl 14): 11 14.
3. 3. Mayberg HS, Brannan SK, Mahurin RK et al. Cingulate function in depression: a potential predictor of treatment response. Neuroreport 1997;8:1057 1061.
4. 4. Bremner JD, Innis RB, Salomon RM et al. Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Arch Gen Psychiatry 1997;54:364-374.
5. 5. Abercrombie HC, Schaefer SM, Larson CL et al. Metabolic rate in the right amygdala predicts negative affect in depressed patients. Neuroreport 1998;9:3301-3307.
6. 6. Smith GS, Reynolds CF, Pollock B et al. Cerebral glucose metabolic response to combined total sleep deprivation and antidepressant treatment in geriatric depression. Am J Psychiatry 1999;156:683-689.
7. 7. Elkis H, Friedman L, Wise A, Meltzer HY. Meta-analyses of studies of ventricular enlargement and cortical sulcal prominence in mood disorders. Comparisons with controls or patients with schizophrenia. Arch Gen Psychiatry 1995; 52:735 746.
8. 8. Dolan RJ, Calloway SP, Thacker PF, Mann AH. The cerebral cortical appearance in depressed subjects. Psychol Med 1986;16:775-779.
9. 9. Dolan RJ, Calloway SP, Mann AH. Cerebral ventricular size in depressed subjects. Psychol Med 1985;15:873-878.
10. 10. Coffey CE, Wilkinson WE, Weiner RD et al. Quantitative cerebral anatomy in depression. A controlled magnetic resonance imaging study. Arch Gen Psychiatry 1993;50:7 16.
11. 11. Rabins PV, Pearlson GD, AylWard E, Kumar AJ, Dowell K. Cortical magnetic resonance imaging changes in elderly inpatients with major depression. Am J Psychiatry 1991; 148:617 620.
12. 2. Drevets WC, Price JL, Simpson JR et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997;386:824-827.
13. 13. Videbech P. Mri findings in patients with affective disorder: a meta-analysis. Acta Psychiatr Scand 1997;96: 157-168.
14. 14. George MS, Ketter TA, Parekh PI, Horwitz B, Herscovitch P, Post RM. Brain activity during transient sadness and happiness in healthy women. Am J Psychiatry 1995;152:341-351.
15. 15. Lane RD, Reiman EM, Bradley MM et al. Neuroanatomical correlates of pleasant and unpleasant emotion. Neuropsychologia 1997;35:1437 1444.
16. 16. Baxter LRJ, Phelps ME, Mazziotta JC et al. Cerebral metabolic rates for glucose in mood disorders: studies with positron emission tomography and fluorodeoxyglucose F 18. Arch Gen Psychiatry 1985;42:441-447.
17. 17. Martinot JL, Hardy P, Feline A et al. Left prefrontal glucose hypometabolism in the depressed state: a confirmation. Am J Psychiatry 1990;147:1313-1317.
18. 18. Biver F, Goldman S, Delvenne V et al. Frontal and parietal metabolic disturbances in unipolar depression. Biol Psychiatry 1994;36:381-388.
19. 19. Bench CJ, Friston KJ, Brown RG, Frackowiak RS, Dolan RJ. Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical dimensions. Psychol Med 1993;23:579 590.
20. 20. Baxter LR, JR, Schwartz JM, Phelps ME et al. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch Gen Psychiatry 1989;46:243-250.
21. 21. Hurwitz TA, Clark C, Murphy E, Klonoff H, Martin WR, Pate BD. Regional cerebral glucose metabolism in major depressive disorder. Can J Psychiatry 1990;35: 684-688.
22. 22. Bench CJ, Friston KJ, Brown RG, Scott LC, Frackowiak RS, Dolan RJ. The anatomy of melancholia focal abnormalities of cerebral blood flow in major depression. Psychol Med 1992;22:607-615.
23. 23. Dolan RJ, Bench CJ, Brown RG, Scott LC, Friston KJ, Frackowiak RS. Regional cerebral blood flow abnormalities in depressed patients with cognitive impairment. J Neurol Neurosurg Psychiatry 1992;55:768-773.
24. 24. Kling AS, Metter EJ, Riege WH, Kuhl DE. Comparison of PET measurement of local brain glucose metabolism and CAT measurement of brain atrophy in chronic schizophrenia and depression. Am J Psychiatry 1986;143:175-180.
25. 25. Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME. A functional anatomical study of unipolar depression. J Neurosci 1992;12:3628-3641.
26. 26. Mallet L, Mazoyer B, Martinot JL. Functional connectivity in depressive, obsessive-compulsive, and schizophrenic disorders: an explorative correlational analysis of regional cerebral metabolism. Psychiatry Res 1998;82: 83-93.
27. 27. Krishnan KR, McDonald WM, Escalona PR et al. Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Arch Gen Psychiatry 1992;49: 553-557.
28. 28. LeDoux J. Fear and the brain: where have we been, and where are we going? Biol Psychiatry 1998;44:1229 1238.
29. 29. Cohen RM, Semple WE, Gross M et al. Evidence for common alterations in cerebral glucose metabolism in major affective disorders and schizophrenia. Neuropsycho-pharmacology 1989;2:241 254.
30. 30. Leiner HC, Leiner AL, Dow RS. The human cerebro cerebellar system: its computing, cognitive, and language skills. Behav Brain Res 1991;44:113 128.
31. 31. Decety J, Sjoholm H, Ryding E, Stenberg G, Ingvar DH. The cerebellum participates in mental activity: tomographic measurements of regional cerebral blood flow. Brain Res 1990;535:313 317.
32. 32. Grasby PM, Frith CD, Friston KJ, Bench C, Frackowiak RS, Dolan RJ. Functional mapping of brain areas implicated in auditory verbal memory function. Brain 1993;116:1 20.
33. 33. Schmahmann JD. An emerging concept. The cerebellar contribution to higher function. Arch Neurol 1991;48: 1178 1187.
34. 34. Shah SA, Doraiswamy PM, Husain MM et al. Posterior fossa abnormalities in major depression: a controlled magnetic resonance imaging study. Acta Psychiatr Scand 1992; 85:474-479.
35. 35. Kornstein SG. Gender differences in depression: implications for treatment. J Clin Psychiatry 1997;58(Suppl 15): 12-18.
36. 36. Murphy DG, DeCarli C, McIntosh AR et al. Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch Gen Psychiatry 1996;53:585-594.
37. 37. Andreason PJ, Zametkin AJ, Guo AC, Baldwin P, Cohen RM. Gender-related differences in regional cerebral glucose metabolism in normal volunteers. Psychiatry Res 1994;51: 175-183.
38. 38. George MS, Ketter TA, Parekh PI, Herscovitch P, Post RM. Gender differences in regional cerebral blood flow during transient self-induced sadness or happiness. Biol Psychiatry 1996;40:859 871.
39. 39. Gur RC, Mozley LH, Mozley PD et al. Sex differences in regional cerebral glucose metabolism during a resting state. Science 1995;267:528-531.
40. 40. Baxter LR JR, Mazziotta JC, Phelps ME et al. Cerebral glucose metabolic rates in normal human females versus normal males. Psychiatry Res 1987;21:237-245.
41. 41. Volkow ND, Wang GJ, Fowler JS et al. Gender differences in cerebellar metabolism: test retest reproducibility. Am J Psychiatry 1997;154:119-121.
42. 42. Mozley PD, Sadek AM, Alavi A et al. Effects of aging on the cerebral distribution of technetium-99m hexamethylpropylene amine oxime in healthy humans. Eur J Nucl Med 1997;24:754-761.
43. 43. Petit-Taboue MC, Landeau B, Desson JF, Desgranges B, Baron JC. Effects of healthy aging on the regional cerebral metabolic rate of glucose assessed with statistical parametric mapping. Neuroimage 1998;7:176 184.
44. 44. Loessner A, Alavi A, Lewandrowski KU, Mozley D, Souder E, Gur RE. Regional cerebral function determined by FDG-PET in healthy volunteers: normal patterns and changes with age. J Nucl Med 1995;36:1141 1149.
45. 45. Eustache F, Rioux P, Desgranges B et al. Healthy aging, memory subsystems and regional cerebral oxygen consumption. Neuropsychologia 1995;33:867 887.
46. 46. Takada H, Nagata K, Hirata Y et al. Age-relaled decline of cerebral oxygen metabolism in normal population detected with positron emission tomography. Neurol Res 1992;14(Suppl 2):128 131.
47. 47. De Leon MJ, George AE, Tomanelli J et al. Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG. Neurobiol Aging 1987;8:319 323.
48. 48. Leibenluft E. Sex is complex (editorial). Am J Psychiatry 1996;153:969 972.
49. 49. De Santi S, De Leon MJ, Convit A et al. Age-related changes in brain: II. Positron emission tomography of frontal and temporal lobe glucose metabolism in normal subjects. Psychiatr Q 1995;66:357 370.
50. 50. Salmon E, Maquet P, Sadzot B, Degueldre C, Lemaire C, Franck G. Decrease of frontal metabolism demonstrated by positron emission tomography in a population of healthy elderly volunteers. Acta Neurol Belg 1991;91:288 295.
51. 51. Waldemar G, Hasselbalch SG, Andersen AR et al. 99 mTc-d,I-HMPAO and SPECT of the brain in normal aging. J Cereb Blood Flow Metab 1991;11:508 521.
52. 52. Martin AJ, Friston KJ, Colebatch JG, Frackowiak RS. Decreases in regional cerebral blood flow with normal aging. J Cereb Blood Flow Metab 1991;11:684-689.
53. 53. Gur RC, Gur RE, Obrist WD, Skolnick BE, Reivich M. Age and regional cerebral blood flow at rest and during cognitive activity. Arch Gen Psychiatry 1987;44:617 621.
54. 54. Covey LS, Glassman AH, Stetner F. Cigarette smoking and major depression. J Addict Dis 1998;17:35-46.
55. 55. Delvenne V, Goldman S, Biver F et al. Brain hypometabolism of glucose in low-weight depressed patients and in anorectic patients: a consequence of starvation? J Affect Disord 1997;44:69-77.
56. 56. Hagman JO, Buchsbaum MS, Wu JC, Rao SJ, Reynolds CA, Blinder BJ. Comparison of regional brain metabolism in bulimia nervosa and affective disorder assessed with positron emission tomography. J Affect Disord 1990;19: 153 162.
57. 57. Buchsbaum MS, Delisi LE, Holcomb HH et al. Anteroposterior gradients in cerebral glucose use in schizophrenia and affective disorders. Arch Gen Psychiatry 1984;41: 1159 1166.
58. 58. Knight RT, Thierry A-M, Glowinski J, Goldman-Rakic PS, Christen Y, eds. Attention regulation and human prefrontal cortex. Motor and cognitive functions of the prefrontal cortex. Berlin: Springer-Verlag, 1994:160 173.
59. 59. Meyer JH, Kennedy S, Brown GM. No effect of depression on [(15)O]H2O PET response to intravenous d-fenfluramine. Am J Psychiatry 1998;155:1241 1246.
60. 18F]2-deoxyglucose in affective illness. J Affect Disord 1986;10:137 152.
61. 61. Post RM, DeLisi LE, Holcomb HH, Uhde TW, Cohen R, Buchsbaum MS. Glucose utilization in the temporal cortex of affectively ill patients: positron emission tomography. Biol Psychiatry 1987;22:545-553.
62. 62. Paradiso S, Lamberty GJ, Garvey MJ, Robinson RG. Cognitive impairment in the euthymic phase of chronic unipolar depression. J Nerv Ment Dis 1997;185:748 754.
63. 15O PET study of the stroop and an emotional stroop. Hum Brain Mapping 1994;1:194-209.
64. 15O PET study of Stroop task performance. Neuroimage 1995; 2:264-272.
65. 65. George MS, Ketter TA, Parekh PI et al. Blunted left cingulate activation in mood disorder subjects during a response interference task (the Stroop). J Neuropsychiatry Clin Neurosci 1997;9:55 63.
66. 66. Elliott R, Baker SC, Rogers RD et al. Prefrontal dysfunction in depressed patients performing a complex planning task: a study using positron emission tomography. Psychol Med 1997;27:931 942.
67. 67. Elliott R, Sahakian BJ, Michael A, Paykel ES, Dolan RJ. Abnormal neural response to feedback on planning and guessing tasks in patients with unipolar depression. Psychol Med 1998;28:559 571.
68. 68. Frith CD, Friston K, Liddle PF, Frackowiak RS. Willed action and the prefrontal cortex in man: a study with PET. Proc R Soc Lond B Biol Sci 1991;244:241 -246.
69. 69. Chua SE, McKenna PJ. Schizophrenia a brain disease? A critical review of structural and functional cerebral abnormality in the disorder. Br J Psychiatry 1995;166: 563 582.
70. 70. Dolan RJ, Bench CJ, Liddle PF et al. Dorsolateral prefrontal cortex dysfunction in the major psychoses; symptom or disease specificity? J Neurol Neurosurg Psychiatry 1993;56:1290 1294.
71. 71. Buchsbaum MS, Wu J, Siegel BV et al. Effect of sertraline on regional metabolic rate in patients with affective disorder. Biol Psychiatry 1997;41:15-22.
72. 72. Wu JC, Gillin JC, Buchsbaum MS, Hershey T, Johnson JC, Bunney WEJ. Effect of sleep deprivation on brain metabolism of depressed patients. Am J Psychiatry 1992;149:538 543.
73. 73. Bench CJ, Frackowiak RSJ, Dolan RJ. Changes in regional cerebral blood flow on recovery from depression. Psychol Med 1995;25:247 261.
74. 74. Trichard C, Martinot JL, Alagille M et al. Time course of prefrontal lobe dysfunction in severely depressed inpatients: a longitudinal neuropsychological study. Psychol Med 1995;25:79 85.
75. 75. McKay AP, Tarbuck AF, Shapleske J, McKenna PJ. Neuropsychological function in manic-depressive psychosis. Evidence for persistent deficits in patients with chronic, severe illness. Br J Psychiatry 1995;167:51 57.
76. 76. Little JT, Ketter TA, Kimbrell TA et al. Venlafaxine or bupropion responders but not nonresponders show baseline prefrontal and paralimbic hypometabolism compared with controls. Psychopharmacol Bull 1996;32:629 635.