Development of highly porous large PLGA microparticles for pulmonary drug delivery

Biomaterials

Volumn 30, Issue 10, 2009, Pages 1947-1953

  Yang, Yan ^a,b   Bajaj, Nimisha ^c   Xu, Peisheng ^a   Ohn, Kimberly ^d   Tsifansky, Michael D ^e   Yeo, Yoon ^a,c  

^a PURDUE UNIVERSITY   (United States)

^b JILIN UNIVERSITY   (China)

^c PURDUE UNIVERSITY   (United States)

^d PURDUE UNIVERSITY   (United States)

^e Advocate Lutheran General Children's Hospital   (United States)

Author keywords

Ammonium bicarbonate; Highly porous large microparticles; Inhalable dry powder; Inhalational therapy; Sustained drug delivery

Indexed keywords

AMMONIUM BICARBONATE; HIGHLY POROUS LARGE MICROPARTICLES; INHALABLE DRY POWDER; INHALATIONAL THERAPY; SUSTAINED DRUG DELIVERY;

AERODYNAMICS; AIR; AMMONIUM COMPOUNDS; ANTIGEN-ANTIBODY REACTIONS; CARBON DIOXIDE; COCHANNEL INTERFERENCE; CONTROLLED DRUG DELIVERY; DRUG DELIVERY; EMULSIFICATION; ENCAPSULATION; ENZYMES; GAS DYNAMICS; MACROPHAGES; METEOROLOGICAL INSTRUMENTS; POWDERS;

DRUG THERAPY;

AMMONIA; CARBON DIOXIDE; DOXORUBICIN; LYSOZYME; POLYGLACTIN; POROUS POLYMER;

ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; EMULSION; ENCAPSULATION; FRACTIONATION; INHALATIONAL DRUG ADMINISTRATION; INHALER; MACROPHAGE; MICROENCAPSULATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PARTICLE SIZE; PHAGOCYTOSIS; POROSITY; PRIORITY JOURNAL; TRACHEA;

ANIMALS; BICARBONATES; CELLS, CULTURED; DOXORUBICIN; DRUG DELIVERY SYSTEMS; LACTIC ACID; MACROPHAGES; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYGLYCOLIC ACID;

EID: 59649112391     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2008.12.044     Document Type: Article

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