Cutting edge: Acute lung allograft rejection is independent of secondary lymphoid organs

Journal of Immunology

Volumn 182, Issue 7, 2009, Pages 3969-3973

  Gelman, Andrew E ^a,b   Li, Wenjun ^a   Richardson, Steven B ^a   Zinselmeyer, Bernd H ^b   Lai, Jiaming ^a   Okazaki, Mikio ^a   Kornfeld, Christopher G ^a   Kreisel, Friederike H ^b   Sugimoto, Seiichiro ^a   Tietjens, Jeremy R ^a   Dempster, John ^c   Patterson, G Alexander ^a   Krupnick, Alexander S ^a   Miller, Mark J ^b   Kreisel, Daniel ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P 15095;

ACUTE GRAFT REJECTION; ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HEART LUNG TRANSPLANTATION; LUNG GRAFT REJECTION; LYMPHOID ORGAN; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; ADOPTIVE TRANSFER; ALLOTRANSPLANTATION; ANIMAL; FLUORESCENCE MICROSCOPY; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LUNG TRANSPLANTATION; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE;

ADOPTIVE TRANSFER; ANIMALS; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; LUNG TRANSPLANTATION; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MICE; MICROSCOPY, FLUORESCENCE; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS;

EID: 64249096629     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803514     Document Type: Article

References (23)

1. Medawar, P. B. 1958. The homograft reaction. Proc. R. Soc. London 149: 145-166.
2. Barker, C. F., and R. E. Billingham. 1968. The role of afferent lymphatics in the rejection of skin homografts. J. Exp. Med. 128: 197-221.
3. Lakkis, F. G., A. Arakelov, B. T. Konieczny, and Y. Inoue. 2000. Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat. Med. 6: 686-688.
4. Zhou, P., K. W. Hwang, D. Palucki, O. Kim, K. A. Newell, Y. X. Fu, and M. L. Alegre. 2003. Secondary lymphoid organs are important but not absolutely required for allograft responses. Am. J. Transplant. 3: 259-266. (Pubitemid 36407042)
5. Wang, J., Y. Dong, J. Z. Sun, R. T. Taylor, C. Guo, M. L. Alegre, I. R. Williams, and K. A. Newell. 2006. Donor lymphoid organs are a major site of alloreactive T-cell priming following intestinal transplantation. Am. J. Transplant. 6: 2563-2571. (Pubitemid 44571676)
6. Beilhack, A., S. Schulz, J. Baker, G. F. Beilhack, R. Nishimura, E. M. Baker, G. Landan, E. I. Herman, E. C. Butcher, C. H. Contag, and R. S. Negrin. 2007. Prevention of acute graft-versus-host disease by blocking T-cell entry to secondary lymphoid organs. Blood 111: 2919-2928.
7. + T cells during pulmonary influenza virus infection. J. Immunol. 173: 1209-1218.
8. + T cells in the draining lymph nodes in response to pulmonary virus infection. J. Immunol. 179: 391-399.
9. Ingulli, E., C. Funatake, E. L. Jacovetty, and M. Zanetti. 2009. Cutting edge: antigen presentation to CD8 T cells after influenza A virus infection. J. Immunol. 182: 29-33.
10. Constant, S. L., J. L. Brogdon, D. A. Piggott, C. A. Herrick, I. Visintin, N. H. Ruddle, and K. Bottomly. 2002. Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. J. Clin. Invest. 110: 1441-1448.
11. Moyron-Quiroz, J. E., J. Rangel-Moreno, K. Kusser, L. Hartson, F. Sprague, S. Goodrich, D. L. Woodland, F. E. Lund, and T. D. Randall. 2004. Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat. Med. 10: 927-934.
12. Okazaki, M., A. S. Krupnick, C. G. Kornfeld, J. M. Lai, J. H. Ritter, S. B. Richardson, H. J. Huang, N. A. Das, G. A. Patterson, A. E. Gelman, and D. Kreisel. 2007. A mouse model of orthotopic vascularized aerated lung transplantation. Am. J. Transplant. 7: 1672-1679. (Pubitemid 46776257)
13. + T cell behavior in mucosal and systemic lymphoid tissues during the induction of oral priming and tolerance. J. Exp. Med. 201: 1815-1823.
14. Okazaki, M., A. E. Gelman, J. R. Tietjens, A. Ibricevic, C. G. Kornfeld, H. J. Huang, S. B. Richardson, J. Lai, J. R. Garbow, G. A. Patterson, et al. 2007. Maintenance of airway epithelium in acutely rejected orthotopic vascularized mouse lung transplants. Am. J. Respir. Cell Mol. Biol. 37: 625-630. (Pubitemid 350211632)
15. McGregor, C. G., J. C. Baldwin, S. W. Jamieson, M. E. Billingham, S. A. Yousem, C. M. Burke, P. E. Oyer, E. B. Stinson, and N. E. Shumway. 1985. Isolated pulmonary rejection after combined heart-lung transplantation. J. Thorac. Cardiovasc. Surg. 90: 623-626. (Pubitemid 16238057)
16. Chalasani, G., Z. Dai, B. T. Konieczny, F. K. Baddoura, and F. G. Lakkis. 2002. Recall and propagation of allospecific memory T cells independent of secondary lymphoid organs. Proc. Natl. Acad. Sci. USA 99: 6175-6180. (Pubitemid 34493285)
17. Larsen, C. P., P. J. Morris, and J. M. Austyn. 1990. Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection. J. Exp. Med. 171: 307-314.
18. Tesar, B. M., G. Chalasani, L. Smith-Diggs, F. K. Baddoura, F. G. Lakkis, and D. R. Goldstein. 2004. Direct antigen presentation by a xenograft induces immunity independently of secondary lymphoid organs. J. Immunol. 173: 4377-4386.
19. Nasr, I. W., M. Reel, M. H. Oberbarnscheidt, R. H. Mounzer, F. K. Baddoura, N. H. Ruddle, and F. G. Lakkis. 2007. Tertiary lymphoid tissues generate effector and memory T cells that lead to allograft rejection. Am. J. Transplant. 7: 1071-1079.
20. Hricik, D. E., V. Rodriguez, J. Riley, K. Bryan, M. Tary-Lehmann, N. Greenspan, C. Dejelo, J. A. Schulak, and P. S. Heeger. 2003. Enzyme linked immunosorbent spot (ELISPOT) assay for interferon-γ independently predicts renal function in kidney transplant recipients. Am. J. Transplant. 3: 878-884.
21. Feuerer, M., P. Beckhove, N. Garbi, Y. Mahnke, A. Limmer, M. Hommel, G. J. Hammerling, B. Kyewski, A. Hamann, V. Umansky, and V. Schirrmacher. 2003. Bone marrow as a priming site for T-cell responses to blood-borne antigen. Nat. Med. 9: 1151-1157. (Pubitemid 37173699)
22. Prop, J., C. R. Wildevuur, and P. Nieuwenhuis. 1985. Lung allograft rejection in the rat. II. Specific immunological properties of lung grafts. Transplantation 40: 126-131. (Pubitemid 15007311)
23. Pabst, R., and I. Gehrke. 1990. Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans?. Am. J. Respir. Cell Mol. Biol. 3: 131-135.