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Volumn 63, Issue 4, 2004, Pages 709-718

Coping with endothelial superoxide: Potential complementarity of arginine and high-dose folate

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; ARGININE; ASCORBIC ACID; CYANOCOBALAMIN; DIMETHYLARGININASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOLIC ACID; HOMOCYSTEINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; OXIDIZING AGENT; POLICOSANOL; RALOXIFENE; SUPEROXIDE; TETRAHYDROBIOPTERIN;

EID: 8444221172     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2002.11.006     Document Type: Article
Times cited : (18)

References (160)
  • 1
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H., Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87:2000;840-844
    • (2000) Circ. Res. , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 3
    • 0032821070 scopus 로고    scopus 로고
    • Identification of a functional leukocyte-type NADPH oxidase in human endothelial cells: A potential atherogenic source of reactive oxygen species
    • Meyer J.W., Holland J.A., Ziegler L.M., Chang M.M., Beebe G., Schmitt M.E. Identification of a functional leukocyte-type NADPH oxidase in human endothelial cells: a potential atherogenic source of reactive oxygen species. Endothelium. 7:1999;11-22
    • (1999) Endothelium , vol.7 , pp. 11-22
    • Meyer, J.W.1    Holland, J.A.2    Ziegler, L.M.3    Chang, M.M.4    Beebe, G.5    Schmitt, M.E.6
  • 4
    • 0033215046 scopus 로고    scopus 로고
    • Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: Role of membrane-bound NADH-/NADPH-oxidases
    • Zhang H., Schmeisser A., Garlichs C.D., Plotze K., Damme U., Mugge A., et al. Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases. Cardiovasc. Res. 44:1999;215-222
    • (1999) Cardiovasc. Res. , vol.44 , pp. 215-222
    • Zhang, H.1    Schmeisser, A.2    Garlichs, C.D.3    Plotze, K.4    Damme, U.5    Mugge, A.6
  • 5
    • 0031443412 scopus 로고    scopus 로고
    • Endothelial function and oxidant stress
    • Harrison D.G. Endothelial function and oxidant stress. Clin. Cardiol. 20:1997;II-7
    • (1997) Clin. Cardiol. , vol.20 , pp. 7
    • Harrison, D.G.1
  • 7
    • 0031874893 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and endothelial function
    • Cosentino F., Luscher T.F. Tetrahydrobiopterin and endothelial function. Eur. Heart. J. 19(Suppl G):1998;G3-G8
    • (1998) Eur. Heart. J. , vol.19 , Issue.SUPPL. G
    • Cosentino, F.1    Luscher, T.F.2
  • 8
    • 0034837885 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction: Does tetrahydrobiopterin play a role?
    • Katusic Z.S. Vascular endothelial dysfunction: does tetrahydrobiopterin play a role? Am. J. Physiol. Heart Circ. Physiol. 281:2001;H981-H986
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.281
    • Katusic, Z.S.1
  • 9
    • 0037086565 scopus 로고    scopus 로고
    • The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: An EPR spin trapping study
    • Vasquez-Vivar J., Martasek P., Whitsett J., Joseph J., Kalyanaraman B. The ratio between tetrahydrobiopterin and oxidized tetrahydrobiopterin analogues controls superoxide release from endothelial nitric oxide synthase: an EPR spin trapping study. Biochem. J. 362:2002;733-739
    • (2002) Biochem. J. , vol.362 , pp. 733-739
    • Vasquez-Vivar, J.1    Martasek, P.2    Whitsett, J.3    Joseph, J.4    Kalyanaraman, B.5
  • 10
    • 0036652942 scopus 로고
    • The physiology of endothelial xanthine oxidase: From urate catabolism to reperfusion injury to inflammatory signal transduction
    • Meneshian A., Bulkley G.B. The physiology of endothelial xanthine oxidase: from urate catabolism to reperfusion injury to inflammatory signal transduction. Microcirculation. 9:1902;161-175
    • (1902) Microcirculation , vol.9 , pp. 161-175
    • Meneshian, A.1    Bulkley, G.B.2
  • 11
    • 0036314940 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury of retinal endothelium by cyclooxygenase- and xanthine oxidase-derived superoxide
    • Rieger J.M., Shah A.R., Gidday J.M. Ischemia-reperfusion injury of retinal endothelium by cyclooxygenase- and xanthine oxidase-derived superoxide. Exp. Eye Res. 74:2002;493-501
    • (2002) Exp. Eye Res. , vol.74 , pp. 493-501
    • Rieger, J.M.1    Shah, A.R.2    Gidday, J.M.3
  • 12
    • 0036065962 scopus 로고    scopus 로고
    • Vasoprotection by nitric oxide: Mechanisms and therapeutic potential
    • Gewaltig M.T., Kojda G. Vasoprotection by nitric oxide: mechanisms and therapeutic potential. Cardiovasc. Res. 55:2002;250-260
    • (2002) Cardiovasc. Res. , vol.55 , pp. 250-260
    • Gewaltig, M.T.1    Kojda, G.2
  • 13
    • 0034033581 scopus 로고    scopus 로고
    • Pharmacological concentrations of ascorbic acid are required for the beneficial effect on endothelial vasomotor function in hypertension
    • Sherman D.L., Keaney J.F.J., Biegelsen E.S., Duffy S.J., Coffrnan J.D., Vita J.A. Pharmacological concentrations of ascorbic acid are required for the beneficial effect on endothelial vasomotor function in hypertension. Hypertension. 35:2000;936-941
    • (2000) Hypertension , vol.35 , pp. 936-941
    • Sherman, D.L.1    Keaney, J.F.J.2    Biegelsen, E.S.3    Duffy, S.J.4    Coffrnan, J.D.5    Vita, J.A.6
  • 14
    • 0034812039 scopus 로고    scopus 로고
    • Mechanisms responsible for endothelial dysfunction induced by fasting hyperhomocystinemia in normotensive subjects and patients with essential hypertension
    • Virdis A., Ghiadoni L., Cardinal H., Favilla S., Duranti P., Birindelli R., et al. Mechanisms responsible for endothelial dysfunction induced by fasting hyperhomocystinemia in normotensive subjects and patients with essential hypertension. J. Am. Coll. Cardiol. 38:2001;1106-1115
    • (2001) J. Am. Coll. Cardiol. , vol.38 , pp. 1106-1115
    • Virdis, A.1    Ghiadoni, L.2    Cardinal, H.3    Favilla, S.4    Duranti, P.5    Birindelli, R.6
  • 15
    • 0030034465 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus
    • Ting H.H., Timimi F.K., Boles K.S., Creager S.J., Ganz P., Creager M.A. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus. J. Clin. Invest. 97:1996;22-28
    • (1996) J. Clin. Invest. , vol.97 , pp. 22-28
    • Ting, H.H.1    Timimi, F.K.2    Boles, K.S.3    Creager, S.J.4    Ganz, P.5    Creager, M.A.6
  • 16
    • 0030187648 scopus 로고    scopus 로고
    • Antioxidant vitamin C improves endothelial dysfunction in chronic smokers
    • Heitzer T., Just H., Munzel T. Antioxidant vitamin C improves endothelial dysfunction in chronic smokers. Circulation. 94:1996;6-9
    • (1996) Circulation , vol.94 , pp. 6-9
    • Heitzer, T.1    Just, H.2    Munzel, T.3
  • 17
    • 0030997880 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation in forearm resistance vessels of humans with hypercholesterolemia
    • Ting H.H., Timimi F.K., Haley E.A., Roddy M.A., Ganz P., Creager M.A. Vitamin C improves endothelium-dependent vasodilation in forearm resistance vessels of humans with hypercholesterolemia. Circulation. 95:1997;2617-2622
    • (1997) Circulation , vol.95 , pp. 2617-2622
    • Ting, H.H.1    Timimi, F.K.2    Haley, E.A.3    Roddy, M.A.4    Ganz, P.5    Creager, M.A.6
  • 18
    • 0030782969 scopus 로고    scopus 로고
    • Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients
    • Solzbach U., Hornig B., Jeserich M., Just H. Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation. 96:1997;1513-1519
    • (1997) Circulation , vol.96 , pp. 1513-1519
    • Solzbach, U.1    Hornig, B.2    Jeserich, M.3    Just, H.4
  • 19
    • 0030669483 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: Effect of vitamin C
    • Motoyama T., Kawano H., Kugiyama K., Hirashima O., Ohgushi M., Yoshimura M., et al. Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: effect of vitamin C. Am. J. Physiol. 273:1997;H1644-H1650
    • (1997) Am. J. Physiol. , vol.273
    • Motoyama, T.1    Kawano, H.2    Kugiyama, K.3    Hirashima, O.4    Ohgushi, M.5    Yoshimura, M.6
  • 20
    • 0032031605 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus
    • Timimi F.K., Ting H.H., Haley E.A., Roddy M.A., Ganz P., Creager M.A. Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. J. Am. Coll. Cardiol. 31:1998;552-557
    • (1998) J. Am. Coll. Cardiol. , vol.31 , pp. 552-557
    • Timimi, F.K.1    Ting, H.H.2    Haley, E.A.3    Roddy, M.A.4    Ganz, P.5    Creager, M.A.6
  • 21
    • 0032499667 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension
    • Taddei S., Virdis A., Ghiadoni L., Magagna A., Salvetti A. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension. Circulation. 97:1998;2222-2229
    • (1998) Circulation , vol.97 , pp. 2222-2229
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Salvetti, A.5
  • 22
    • 0032530589 scopus 로고    scopus 로고
    • Comparison of effects of ascorbic acid on endothelium-dependent vasodilation in patients with chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy versus patients with effort angina pectoris secondary to coronary artery disease
    • Ito K., Akita H., Kanazawa K., Yamada S., Terashima M., Matsuda Y., et al. Comparison of effects of ascorbic acid on endothelium-dependent vasodilation in patients with chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy versus patients with effort angina pectoris secondary to coronary artery disease. Am. J. Cardiol. 82:1998;762-767
    • (1998) Am. J. Cardiol. , vol.82 , pp. 762-767
    • Ito, K.1    Akita, H.2    Kanazawa, K.3    Yamada, S.4    Terashima, M.5    Matsuda, Y.6
  • 23
    • 0033817532 scopus 로고    scopus 로고
    • Effects of atorvastatin and vitamin C on endothelial function of hypercholesterolemic patients
    • Perticone F., Ceravolo R., Maio R., Cloro C., Candigliota M., Scozzafava A., et al. Effects of atorvastatin and vitamin C on endothelial function of hypercholesterolemic patients. Atherosclerosis. 152:2000;511-518
    • (2000) Atherosclerosis , vol.152 , pp. 511-518
    • Perticone, F.1    Ceravolo, R.2    Maio, R.3    Cloro, C.4    Candigliota, M.5    Scozzafava, A.6
  • 25
    • 0035152499 scopus 로고    scopus 로고
    • Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: Protective effect of vitamin C
    • Perticone F., Ceravolo R., Candigliota M., Venture G., lacopino S., Sinopoli F., et al. Obesity and body fat distribution induce endothelial dysfunction by oxidative stress: protective effect of vitamin C. Diabetes. 50:2001;159-165
    • (2001) Diabetes , vol.50 , pp. 159-165
    • Perticone, F.1    Ceravolo, R.2    Candigliota, M.3    Venture, G.4    Lacopino, S.5    Sinopoli, F.6
  • 26
    • 0035957267 scopus 로고    scopus 로고
    • Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans
    • Beckman J.A., Goldfine A.B., Gordon M.B., Creager M.A. Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans. Circulation. 103:2001;1618-1623
    • (2001) Circulation , vol.103 , pp. 1618-1623
    • Beckman, J.A.1    Goldfine, A.B.2    Gordon, M.B.3    Creager, M.A.4
  • 27
    • 0034448115 scopus 로고    scopus 로고
    • Effect of ascorbic acid on endothelial dysfunction of epicardial coronary arteries in chronic smokers assessed by cold pressor testing
    • Schindler T.H., Magosaki N., Jeserich M., Olschewski M., Nitzsche E., Holubarsch C., et al. Effect of ascorbic acid on endothelial dysfunction of epicardial coronary arteries in chronic smokers assessed by cold pressor testing. Cardiology. 94:2000;239-246
    • (2000) Cardiology , vol.94 , pp. 239-246
    • Schindler, T.H.1    Magosaki, N.2    Jeserich, M.3    Olschewski, M.4    Nitzsche, E.5    Holubarsch, C.6
  • 28
    • 0035873316 scopus 로고    scopus 로고
    • Impaired endothelium-dependent vasodilation in the brachial artery in variant angina pectoris and the effect of intravenous administration of vitamin C
    • Hamabe A., Takase B., Uehata A., Kurita A., Ohsuzu F., Tamai S. Impaired endothelium-dependent vasodilation in the brachial artery in variant angina pectoris and the effect of intravenous administration of vitamin C. Am. J. Cardiol. 87:2001;1154-1159
    • (2001) Am. J. Cardiol. , vol.87 , pp. 1154-1159
    • Hamabe, A.1    Takase, B.2    Uehata, A.3    Kurita, A.4    Ohsuzu, F.5    Tamai, S.6
  • 32
    • 0024340138 scopus 로고
    • Purification and properties of a new enzyme, NG,NG- dimethylarginine dimethylaminohydrolase, from rat kidney
    • Ogawa T., Kimoto M., Sasaoka K. Purification and properties of a new enzyme, NG,NG- dimethylarginine dimethylaminohydrolase, from rat kidney. J. Biol. Chem. 264:1989;10205-10209
    • (1989) J. Biol. Chem. , vol.264 , pp. 10205-10209
    • Ogawa, T.1    Kimoto, M.2    Sasaoka, K.3
  • 33
    • 0033214074 scopus 로고    scopus 로고
    • Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases
    • Leiper J.M., Santa M.J., Chubb A., MacAllister R.J., Charles I.G., Whitley G.S., et al. Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. Biochem. J. 343(Pt 1):1999;209-214
    • (1999) Biochem. J. , vol.343 , Issue.PART 1 , pp. 209-214
    • Leiper, J.M.1    Santa, M.J.2    Chubb, A.3    MacAllister, R.J.4    Charles, I.G.5    Whitley, G.S.6
  • 36
    • 0033566683 scopus 로고    scopus 로고
    • Biological significance of endogenous methylarginines that inhibit nitric oxide synthases
    • Leiper J., Vallance P. Biological significance of endogenous methylarginines that inhibit nitric oxide synthases. Cardiovasc. Res. 43:1999;542-548
    • (1999) Cardiovasc. Res. , vol.43 , pp. 542-548
    • Leiper, J.1    Vallance, P.2
  • 37
    • 0033594888 scopus 로고    scopus 로고
    • Novel mechanism for endothelial dysfunction: Dysregulation of dimethylarginine dimethylaminohydrolase
    • Ito A., Tsao P.S., Adimoolam S., Kimoto M., Ogawa T., Cooke J.P. Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase. Circulation. 99:1999;3092-3095
    • (1999) Circulation , vol.99 , pp. 3092-3095
    • Ito, A.1    Tsao, P.S.2    Adimoolam, S.3    Kimoto, M.4    Ogawa, T.5    Cooke, J.P.6
  • 38
    • 0035923560 scopus 로고    scopus 로고
    • Homocysteine impairs the nitric oxide synthase pathway: Role of asymmetric dimethylarginine
    • Stuhlinger M.C., Tsao P.S., Her J.H., Kimoto M., Balint R.F., Cooke J.P. Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine. Circulation. 104:2001;2569-2575
    • (2001) Circulation , vol.104 , pp. 2569-2575
    • Stuhlinger, M.C.1    Tsao, P.S.2    Her, J.H.3    Kimoto, M.4    Balint, R.F.5    Cooke, J.P.6
  • 39
    • 0037139438 scopus 로고    scopus 로고
    • Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor
    • Stuhlinger M.C., Abbasi F., Chu J.W., Lamendola C., McLaughlin T.L., Cooke J.P., et al. Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor. JAMA. 287:2002;1420-1426
    • (2002) JAMA , vol.287 , pp. 1420-1426
    • Stuhlinger, M.C.1    Abbasi, F.2    Chu, J.W.3    Lamendola, C.4    McLaughlin, T.L.5    Cooke, J.P.6
  • 40
    • 2542505412 scopus 로고    scopus 로고
    • Vascular endothelium is the organ chiefly responsible for the catabolism of plasma asymmetric dimethylarginine - An explanation for the elevation of plasma ADMA in disorders characterized by endothelial dysfunction
    • (in press)
    • McCarty MF. Vascular endothelium is the organ chiefly responsible for the catabolism of plasma asymmetric dimethylarginine - an explanation for the elevation of plasma ADMA in disorders characterized by endothelial dysfunction. Med. Hypotheses; 2002 (in press)
    • (2002) Med. Hypotheses
    • McCarty, M.F.1
  • 41
    • 0033813512 scopus 로고    scopus 로고
    • Does ADMA cause endothelial dysfunction?
    • Cooke J.P. Does ADMA cause endothelial dysfunction? Arterioscler. Thromb. Vasc. Biol. 20:2000;2032-2037
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 2032-2037
    • Cooke, J.P.1
  • 42
    • 0035344247 scopus 로고    scopus 로고
    • Atherogenesis and the arginine hypothesis
    • Cooke J.P., Oka R.K. Atherogenesis and the arginine hypothesis. Curr. Atheroscler. Rep. 3:2001;252-259
    • (2001) Curr. Atheroscler. Rep. , vol.3 , pp. 252-259
    • Cooke, J.P.1    Oka, R.K.2
  • 44
    • 0029124027 scopus 로고
    • Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production
    • Boger R.H., Bode-Boger S.M., Mugge A., Kienke S., Brandes R., Dwenger A., et al. Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production. Atherosclerosis. 317:1995;273-284
    • (1995) Atherosclerosis , vol.317 , pp. 273-284
    • Boger, R.H.1    Bode-Boger, S.M.2    Mugge, A.3    Kienke, S.4    Brandes, R.5    Dwenger, A.6
  • 45
    • 0039550848 scopus 로고    scopus 로고
    • L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells
    • Heller R., Munscher-Paulig F., Grabner R., Till U. L-Ascorbic acid potentiates nitric oxide synthesis in endothelial cells. J. Biol. Chem. 274:1999;8254-8260
    • (1999) J. Biol. Chem. , vol.274 , pp. 8254-8260
    • Heller, R.1    Munscher-Paulig, F.2    Grabner, R.3    Till, U.4
  • 46
    • 0034625391 scopus 로고    scopus 로고
    • Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin
    • Huang A., Vita J.A., Venema R.C., Keaney J.F.J. Ascorbic acid enhances endothelial nitric-oxide synthase activity by increasing intracellular tetrahydrobiopterin. J. Biol. Chem. 275:2000;17399-17406
    • (2000) J. Biol. Chem. , vol.275 , pp. 17399-17406
    • Huang, A.1    Vita, J.A.2    Venema, R.C.3    Keaney, J.F.J.4
  • 49
    • 0033752910 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus
    • Heitzer T., Krohn K., Albers S., Meinertz T. Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia. 43:2000;1435-1438
    • (2000) Diabetologia , vol.43 , pp. 1435-1438
    • Heitzer, T.1    Krohn, K.2    Albers, S.3    Meinertz, T.4
  • 50
    • 0034890205 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelial dysfunction in coronary microcirculation in patients without epicardial coronary artery disease
    • Setoguchi S., Mohri M., Shimokawa H., Takeshita A. Tetrahydrobiopterin improves endothelial dysfunction in coronary microcirculation in patients without epicardial coronary artery disease. J. Am. Coll. Cardiol. 38:2001;493-498
    • (2001) J. Am. Coll. Cardiol. , vol.38 , pp. 493-498
    • Setoguchi, S.1    Mohri, M.2    Shimokawa, H.3    Takeshita, A.4
  • 51
    • 0036182797 scopus 로고    scopus 로고
    • Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia
    • Fukuda Y., Teragawa H., Matsuda K., Yamagata T., Matsuura H., Chayama K. Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia. Heart. 87:2002;264-269
    • (2002) Heart , vol.87 , pp. 264-269
    • Fukuda, Y.1    Teragawa, H.2    Matsuda, K.3    Yamagata, T.4    Matsuura, H.5    Chayama, K.6
  • 52
    • 0036183645 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves impaired endothelium-dependent forearm vasodilation in patients with heart failure
    • Setoguchi S., Hirooka Y., Eshima K., Shimokawa H., Takeshita A. Tetrahydrobiopterin improves impaired endothelium-dependent forearm vasodilation in patients with heart failure. J. Cardiovasc. Pharmacol. 39:2002;363-368
    • (2002) J. Cardiovasc. Pharmacol. , vol.39 , pp. 363-368
    • Setoguchi, S.1    Hirooka, Y.2    Eshima, K.3    Shimokawa, H.4    Takeshita, A.5
  • 53
    • 0036100972 scopus 로고    scopus 로고
    • Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
    • Higashi Y., Sasaki S., Nakagawa K., Fukuda Y., Matsuura H., Oshima T., et al. Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals. Am. J. Hypertens. 15:2002;326-332
    • (2002) Am. J. Hypertens. , vol.15 , pp. 326-332
    • Higashi, Y.1    Sasaki, S.2    Nakagawa, K.3    Fukuda, Y.4    Matsuura, H.5    Oshima, T.6
  • 54
    • 0036234279 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina
    • Fukuda Y., Teragawa H., Matsuda K., Yamagata T., Matsuura H., Chayama K. Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina. Circ. J. 66:2002;58-62
    • (2002) Circ. J. , vol.66 , pp. 58-62
    • Fukuda, Y.1    Teragawa, H.2    Matsuda, K.3    Yamagata, T.4    Matsuura, H.5    Chayama, K.6
  • 56
    • 0034602878 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase
    • Heitzer T., Brockhoff C., Mayer B., Warnholtz A., Mollnau H., Henne S., et al. Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase. Circ. Res. 86:2000;E36-E41
    • (2000) Circ. Res. , vol.86
    • Heitzer, T.1    Brockhoff, C.2    Mayer, B.3    Warnholtz, A.4    Mollnau, H.5    Henne, S.6
  • 57
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • Milstien S., Katusic Z. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem. Biophys. Res. Commun. 263:1999;681-684
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 58
    • 33751290467 scopus 로고    scopus 로고
    • Inhibition of tetrahydrobiopterin biosynthesis impairs endothelium-dependent relaxations in canine basilar artery
    • Kinoshita H., Milstien S., Wambi C., Katusic Z.S. Inhibition of tetrahydrobiopterin biosynthesis impairs endothelium-dependent relaxations in canine basilar artery. Am. J. Physiol. 273:1997;H718-H724
    • (1997) Am. J. Physiol. , vol.273
    • Kinoshita, H.1    Milstien, S.2    Wambi, C.3    Katusic, Z.S.4
  • 59
    • 0034730795 scopus 로고    scopus 로고
    • Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats
    • Shinozaki K., Nishio Y., Okamura T., Yoshida Y., Maegawa H., Kojima H., et al. Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats. Circ. Res. 87:2000;566-573
    • (2000) Circ. Res. , vol.87 , pp. 566-573
    • Shinozaki, K.1    Nishio, Y.2    Okamura, T.3    Yoshida, Y.4    Maegawa, H.5    Kojima, H.6
  • 60
    • 0035129395 scopus 로고    scopus 로고
    • Stimulation of tetrahydrobiopterin synthesis induced by insulin: Possible involvement of phosphatidylinositol 3-kinase
    • Ishii M., Shimizu S., Nagai T., Shiota K., Kiuchi Y., Yamamoto T. Stimulation of tetrahydrobiopterin synthesis induced by insulin: possible involvement of phosphatidylinositol 3-kinase. Int. J. Biochem. Cell. Biol. 33:2001;65-73
    • (2001) Int. J. Biochem. Cell. Biol. , vol.33 , pp. 65-73
    • Ishii, M.1    Shimizu, S.2    Nagai, T.3    Shiota, K.4    Kiuchi, Y.5    Yamamoto, T.6
  • 61
    • 0030464496 scopus 로고    scopus 로고
    • Tetrahydrobiopterin-free neuronal nitric oxide synthase: Evidence for two identical highly anticooperative pteridine binding sites
    • Gorren A.C., List B.M., Schrammel A., Fitters E., Hemmens B., Wemer E.R., et al. Tetrahydrobiopterin-free neuronal nitric oxide synthase: evidence for two identical highly anticooperative pteridine binding sites. Biochemistry. 35:1996;16735-16745
    • (1996) Biochemistry. , vol.35 , pp. 16735-16745
    • Gorren, A.C.1    List, B.M.2    Schrammel, A.3    Fitters, E.4    Hemmens, B.5    Wemer, E.R.6
  • 62
    • 0344073985 scopus 로고    scopus 로고
    • Atherosclerosis and the two faces of endothelial nitric oxide synthase
    • Wever R.M., Luscher T.F., Cosentino F., Rabelink T.J. Atherosclerosis and the two faces of endothelial nitric oxide synthase. Circulation. 97:1998;108-112
    • (1998) Circulation , vol.97 , pp. 108-112
    • Wever, R.M.1    Luscher, T.F.2    Cosentino, F.3    Rabelink, T.J.4
  • 63
    • 0033614813 scopus 로고    scopus 로고
    • Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease
    • Gokce N., Keaney J.F.J., Frei B., Holbrook M., Olesiak M., Zachariah B.J., et al. Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 99:1999;3234-3240
    • (1999) Circulation , vol.99 , pp. 3234-3240
    • Gokce, N.1    Keaney, J.F.J.2    Frei, B.3    Holbrook, M.4    Olesiak, M.5    Zachariah, B.J.6
  • 64
    • 0034332693 scopus 로고    scopus 로고
    • Neutrophil superoxide anion-generating capacity, endothelial function and oxidative stress in chronic heart failure: Effects of short- and long-term vitamin C therapy
    • Ellis G.R., Anderson R.A., Lang D., Blackman D.J., Morris R.H., Morris-Thurgood J., et al. Neutrophil superoxide anion-generating capacity, endothelial function and oxidative stress in chronic heart failure: effects of short- and long-term vitamin C therapy. J. Am. Coll. Cardiol. 36:2000;1474-1482
    • (2000) J. Am. Coll. Cardiol. , vol.36 , pp. 1474-1482
    • Ellis, G.R.1    Anderson, R.A.2    Lang, D.3    Blackman, D.J.4    Morris, R.H.5    Morris-Thurgood, J.6
  • 65
    • 0029986355 scopus 로고    scopus 로고
    • Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease
    • Levine G.N., Frei B., Koulouris S.N., Gerhard M.D., Keaney J.F.J., Vita J.A. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 93:1996;1107-1113
    • (1996) Circulation , vol.93 , pp. 1107-1113
    • Levine, G.N.1    Frei, B.2    Koulouris, S.N.3    Gerhard, M.D.4    Keaney, J.F.J.5    Vita, J.A.6
  • 66
    • 0033537653 scopus 로고    scopus 로고
    • Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: An effect reversible with vitamin C therapy
    • Chambers J.C., McGregor A., Jean-Marie J., Obeid O.A., Kooner J.S. Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation. 99:1999;1156-1160
    • (1999) Circulation , vol.99 , pp. 1156-1160
    • Chambers, J.C.1    McGregor, A.2    Jean-Marie, J.3    Obeid, O.A.4    Kooner, J.S.5
  • 68
    • 0033857931 scopus 로고    scopus 로고
    • Short-term oral ascorbic acid improves endothelium-dependent vasodilatation in women with a history of gestational diabetes mellitus
    • Lekakis J.P., Anastasiou E.A., Papamichael C.M., Stamatelopoulos K.S., Dagre A.G., Alevizaki M.C., et al. Short-term oral ascorbic acid improves endothelium-dependent vasodilatation in women with a history of gestational diabetes mellitus. Diabetes Care. 23:2000;1432-1434
    • (2000) Diabetes Care , vol.23 , pp. 1432-1434
    • Lekakis, J.P.1    Anastasiou, E.A.2    Papamichael, C.M.3    Stamatelopoulos, K.S.4    Dagre, A.G.5    Alevizaki, M.C.6
  • 70
    • 0036234460 scopus 로고    scopus 로고
    • Vitamin C preserves endothelial function in patients with coronary heart disease after a high-fat meal
    • Ling L., Zhao S.P., Gao M., Zhou Q.C., Li Y.L., Xia B. Vitamin C preserves endothelial function in patients with coronary heart disease after a high-fat meal. Clin. Cardiol. 25:2002;219-224
    • (2002) Clin. Cardiol. , vol.25 , pp. 219-224
    • Ling, L.1    Zhao, S.P.2    Gao, M.3    Zhou, Q.C.4    Li, Y.L.5    Xia, B.6
  • 71
    • 0035987991 scopus 로고    scopus 로고
    • Vitamin C therapy ameliorates vascular endothelial dysfunction in treated patients with homocystinuria
    • Pullin C.H., Bonham J.R., McDowell I.F., Lee P.J., Powers H.J., Wilson J.F., et al. Vitamin C therapy ameliorates vascular endothelial dysfunction in treated patients with homocystinuria. J. Inherit. Metab. Dis. 25:2002;107-118
    • (2002) J. Inherit. Metab. Dis. , vol.25 , pp. 107-118
    • Pullin, C.H.1    Bonham, J.R.2    McDowell, I.F.3    Lee, P.J.4    Powers, H.J.5    Wilson, J.F.6
  • 73
    • 0028802762 scopus 로고
    • The uptake of ascorbic acid into human umbilical vein endothelial cells and its effect on oxidant insult
    • Ek A., Strom K., Cotgreave I.A. The uptake of ascorbic acid into human umbilical vein endothelial cells and its effect on oxidant insult. Biochem. Pharmacol. 50:1995;1339-1346
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 1339-1346
    • Ek, A.1    Strom, K.2    Cotgreave, I.A.3
  • 77
    • 0032570254 scopus 로고    scopus 로고
    • 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia
    • Verhaar M.C., Wever R.M., Kastelein J.J., van Dam T., Koomans H.A., Rabelink T.J. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia. Circulation. 97:1998;237-241
    • (1998) Circulation , vol.97 , pp. 237-241
    • Verhaar, M.C.1    Wever, R.M.2    Kastelein, J.J.3    Van Dam, T.4    Koomans, H.A.5    Rabelink, T.J.6
  • 78
    • 0033816515 scopus 로고    scopus 로고
    • The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate
    • De Vriese A.S., Van D.V., Blom H.J., Vanhoutte P.M., Verbeke M., Lameire N.H. The impaired renal vasodilator response attributed to endothelium-derived hyperpolarizing factor in streptozotocin-induced diabetic rats is restored by 5-methyltetrahydrofolate. Diabetologia. 43:2000;1116-1125
    • (2000) Diabetologia , vol.43 , pp. 1116-1125
    • De Vriese, A.S.1    Van, D.V.2    Blom, H.J.3    Vanhoutte, P.M.4    Verbeke, M.5    Lameire, N.H.6
  • 79
    • 0036020286 scopus 로고    scopus 로고
    • Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate
    • Van Etten R.W., De Koning E.J., Verhaar M.C., Gaillard C.A., Rabelink T.J. Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate. Diabetologia. 45:2002;1004-1010
    • (2002) Diabetologia , vol.45 , pp. 1004-1010
    • Van Etten, R.W.1    De Koning, E.J.2    Verhaar, M.C.3    Gaillard, C.A.4    Rabelink, T.J.5
  • 80
    • 0035721992 scopus 로고    scopus 로고
    • Folate improves endothelial function in coronary artery disease: An effect mediated by reduction of intracellular superoxide?
    • Doshi S.N., McDowell I.F., Moat S.J., Lang D., Newcombe R.G., Kredan M.B., et al. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler. Thromb. Vasc. Biol. 21:2001;1196-1202
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1196-1202
    • Doshi, S.N.1    McDowell, I.F.2    Moat, S.J.3    Lang, D.4    Newcombe, R.G.5    Kredan, M.B.6
  • 81
    • 0026072264 scopus 로고
    • Some metabolic relationships between biopterin and folate: Implications for the "methyl trap hypothesis"
    • Kaufman S. Some metabolic relationships between biopterin and folate: implications for the "methyl trap hypothesis" Neurochem. Res. 16:1991;1031-1036
    • (1991) Neurochem. Res. , vol.16 , pp. 1031-1036
    • Kaufman, S.1
  • 82
    • 0033609454 scopus 로고    scopus 로고
    • Effects of oral folic acid supplementation on endothelial function in familial hypercholesterolemia. a randomized placebo-controlled trial
    • Verhaar M.C., Wever R.M., Kastelein J.J., van Loon D., Milstien S., Koomans H.A., et al. Effects of oral folic acid supplementation on endothelial function in familial hypercholesterolemia. A randomized placebo-controlled trial. Circulation. 100:1999;335-338
    • (1999) Circulation , vol.100 , pp. 335-338
    • Verhaar, M.C.1    Wever, R.M.2    Kastelein, J.J.3    Van Loon, D.4    Milstien, S.5    Koomans, H.A.6
  • 83
    • 0036140785 scopus 로고    scopus 로고
    • Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering
    • Doshi S.N., McDowell I.F., Moat S.J., Payne N., Durrant H.J., Lewis M.J., et al. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation. 105:2002;22-26
    • (2002) Circulation , vol.105 , pp. 22-26
    • Doshi, S.N.1    McDowell, I.F.2    Moat, S.J.3    Payne, N.4    Durrant, H.J.5    Lewis, M.J.6
  • 84
    • 0035806914 scopus 로고    scopus 로고
    • Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: A human in vivo study
    • Gori T., Burstein J.M., Ahmed S., Miner S.E., Al-Hesayen A., Kelly S., et al. Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study. Circulation. 104:2001;1119-1123
    • (2001) Circulation , vol.104 , pp. 1119-1123
    • Gori, T.1    Burstein, J.M.2    Ahmed, S.3    Miner, S.E.4    Al-Hesayen, A.5    Kelly, S.6
  • 85
    • 0030968144 scopus 로고    scopus 로고
    • The role of vitamins in the pathogenesis and treatment of hyperhomocyst (e)inaemia
    • Ubbink J.B. The role of vitamins in the pathogenesis and treatment of hyperhomocyst (e)inaemia. J. Inherit. Metab. Dis. 20:1997;316-325
    • (1997) J. Inherit. Metab. Dis. , vol.20 , pp. 316-325
    • Ubbink, J.B.1
  • 86
    • 0029200072 scopus 로고
    • Oxidant-sensitive and phosphorylation-dependent activation of NF-kappa B and AP-1 in endothelial cells
    • Barchowsky A., Munro S.R., Morana S.J., Vincenti M.P., Treadwell M. Oxidant-sensitive and phosphorylation-dependent activation of NF-kappa B and AP-1 in endothelial cells. Am. J. Physiol. 269:1995;L829-L836
    • (1995) Am. J. Physiol. , vol.269
    • Barchowsky, A.1    Munro, S.R.2    Morana, S.J.3    Vincenti, M.P.4    Treadwell, M.5
  • 87
    • 0034060298 scopus 로고    scopus 로고
    • Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress
    • Pueyo M.E., Gonzalez W., Nicoletti A., Savoie F., Arnal J.F., Michel J.B. Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress. Arterioscler. Thromb. Vasc. Biol. 20:2000;645-651
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 645-651
    • Pueyo, M.E.1    Gonzalez, W.2    Nicoletti, A.3    Savoie, F.4    Arnal, J.F.5    Michel, J.B.6
  • 88
    • 0033968564 scopus 로고    scopus 로고
    • Involvement of protein kinase C in superoxide anion-induced activation of nuclear factor-kappa B in human endothelial cells
    • Ogata N., Yamamoto H., Kugiyama K., Yasue H., Miyamoto E. Involvement of protein kinase C in superoxide anion-induced activation of nuclear factor-kappa B in human endothelial cells. Cardiovasc. Res. 45:2000;513-521
    • (2000) Cardiovasc. Res. , vol.45 , pp. 513-521
    • Ogata, N.1    Yamamoto, H.2    Kugiyama, K.3    Yasue, H.4    Miyamoto, E.5
  • 89
    • 0029011129 scopus 로고
    • Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B
    • Peng H.B., Libby P., Liao J.K. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J. Biol. Chem. 270:1995;14214-14219
    • (1995) J. Biol. Chem. , vol.270 , pp. 14214-14219
    • Peng, H.B.1    Libby, P.2    Liao, J.K.3
  • 90
    • 0029159779 scopus 로고
    • Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R., Libby P., Peng H.B., Thannickal V.J., Rajavashisth T.B., Gimbrone M.A.J., et al. Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J. Clin. Invest. 96:1995;60-68
    • (1995) J. Clin. Invest. , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone, M.A.J.6
  • 92
    • 0033635176 scopus 로고    scopus 로고
    • Endothelial dysfunction in atherosclerotic mice: Improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin
    • Jiang J., Valen G., Tokuno S., Thoren P., Pernow J. Endothelial dysfunction in atherosclerotic mice: improved relaxation by combined supplementation with L-arginine-tetrahydrobiopterin and enhanced vasoconstriction by endothelin. Br. J. Pharmacol. 131:2000;1255-1261
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 1255-1261
    • Jiang, J.1    Valen, G.2    Tokuno, S.3    Thoren, P.4    Pernow, J.5
  • 93
    • 0034697249 scopus 로고    scopus 로고
    • A central role for the endothelial NADPH oxidase in atherosclerosis
    • Meyer J.W., Schmitt M.E. A central role for the endothelial NADPH oxidase in atherosclerosis. FEBS Lett. 472:2000;1-4
    • (2000) FEBS Lett. , vol.472 , pp. 1-4
    • Meyer, J.W.1    Schmitt, M.E.2
  • 94
    • 0033779395 scopus 로고    scopus 로고
    • Stimulation of NADPH oxidase by oxidized low-density lipoprotein induces proliferation of human vascular endothelial cells
    • Heinloth A., Heermeier K., Raff U., Wanner C., Galle J. Stimulation of NADPH oxidase by oxidized low-density lipoprotein induces proliferation of human vascular endothelial cells. J. Am. Soc. Nephrol. 11:2000;1819-1825
    • (2000) J. Am. Soc. Nephrol. , vol.11 , pp. 1819-1825
    • Heinloth, A.1    Heermeier, K.2    Raff, U.3    Wanner, C.4    Galle, J.5
  • 95
    • 0035112586 scopus 로고    scopus 로고
    • Lysophosphatidylcholine increases the secretion of matrix metalloproteinase 2 through the activation of NADH/NADPH oxidase in cultured aortic endothelial cells
    • Inoue N., Takeshita S., Gao D., Ishida T., Kawashima S., Akita H., et al. Lysophosphatidylcholine increases the secretion of matrix metalloproteinase 2 through the activation of NADH/NADPH oxidase in cultured aortic endothelial cells. Atherosclerosis. 155:2001;45-52
    • (2001) Atherosclerosis , vol.155 , pp. 45-52
    • Inoue, N.1    Takeshita, S.2    Gao, D.3    Ishida, T.4    Kawashima, S.5    Akita, H.6
  • 96
    • 0035834028 scopus 로고    scopus 로고
    • Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: Antioxidative potential of hydroxymethylglutaryl coenzyme a reductase inhibitor therapy
    • Rueckschloss U., Galle J., Holtz J., Zerkowski H.R., Morawietz H. Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: antioxidative potential of hydroxymethylglutaryl coenzyme A reductase inhibitor therapy. Circulation. 104:2001;1767-1772
    • (2001) Circulation , vol.104 , pp. 1767-1772
    • Rueckschloss, U.1    Galle, J.2    Holtz, J.3    Zerkowski, H.R.4    Morawietz, H.5
  • 97
    • 0032821070 scopus 로고    scopus 로고
    • Identification of a functional leukocyte-type NADPH oxidase in human endothelial cells: A potential atherogenic source of reactive oxygen species
    • Meyer J.W., Holland J.A., Ziegler L.M., Chang M.M., Beebe G., Schmitt M.E. Identification of a functional leukocyte-type NADPH oxidase in human endothelial cells: a potential atherogenic source of reactive oxygen species. Endothelium. 7:1999;11-22
    • (1999) Endothelium , vol.7 , pp. 11-22
    • Meyer, J.W.1    Holland, J.A.2    Ziegler, L.M.3    Chang, M.M.4    Beebe, G.5    Schmitt, M.E.6
  • 98
    • 0033765672 scopus 로고    scopus 로고
    • High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C- dependent activation of NAD(P)H oxidase in cultured vascular cells
    • Inoguchi T., Li P., Umeda F., Yu H.Y., Kakimoto M., Imamura M., et al. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C- dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes. 49:2000;1939-1945
    • (2000) Diabetes , vol.49 , pp. 1939-1945
    • Inoguchi, T.1    Li, P.2    Umeda, F.3    Yu, H.Y.4    Kakimoto, M.5    Imamura, M.6
  • 99
    • 0033393598 scopus 로고    scopus 로고
    • Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats
    • Kashiwagi A., Shinozaki K., Nishio Y., Maegawa H., Maeno Y., Kanazawa A., et al. Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats. Am. J. Physiol. 277:1999;E976-E983
    • (1999) Am. J. Physiol. , vol.277
    • Kashiwagi, A.1    Shinozaki, K.2    Nishio, Y.3    Maegawa, H.4    Maeno, Y.5    Kanazawa, A.6
  • 100
    • 0032882038 scopus 로고    scopus 로고
    • Free radical production in endothelial cells as a pathogenetic factor for vascular dysfunction in the insulin resistance state
    • Kashiwagi A., Shinozaki K., Nishio Y., Okamura T., Toda N., Kikkawa R. Free radical production in endothelial cells as a pathogenetic factor for vascular dysfunction in the insulin resistance state. Diabetes Res. Clin. Pract. 45:1999;199-203
    • (1999) Diabetes Res. Clin. Pract. , vol.45 , pp. 199-203
    • Kashiwagi, A.1    Shinozaki, K.2    Nishio, Y.3    Okamura, T.4    Toda, N.5    Kikkawa, R.6
  • 101
    • 0032709605 scopus 로고    scopus 로고
    • Endothelial membrane potential regulates production of both nitric oxide and superoxide-fundamental determinant of vascular health
    • McCarty M.F. Endothelial membrane potential regulates production of both nitric oxide and superoxide-fundamental determinant of vascular health. Med. Hypotheses. 53:1999;277-289
    • (1999) Med. Hypotheses , vol.53 , pp. 277-289
    • McCarty, M.F.1
  • 102
    • 0037022951 scopus 로고    scopus 로고
    • Endogenous ligand of alpha (l) sodium pump, marinobufagenin, is a novel mediator of sodium chloride-dependent hypertension
    • Fedorova O.V., Talan M.I., Agalakova N.I., Lakatta E.G., Bagrov A.Y. Endogenous ligand of alpha (l) sodium pump, marinobufagenin, is a novel mediator of sodium chloride-dependent hypertension. Circulation. 105:2002;1122-1127
    • (2002) Circulation , vol.105 , pp. 1122-1127
    • Fedorova, O.V.1    Talan, M.I.2    Agalakova, N.I.3    Lakatta, E.G.4    Bagrov, A.Y.5
  • 103
    • 0033860974 scopus 로고    scopus 로고
    • Reactive oxygen species may contribute to reduced endothelium-dependent dilation in rats fed high salt
    • Lenda D.M., Sauls B.A., Boegehold M.A. Reactive oxygen species may contribute to reduced endothelium-dependent dilation in rats fed high salt. Am. J. Physiol. Heart Circ. Physiol. 279:2000;H7-H14
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.279
    • Lenda, D.M.1    Sauls, B.A.2    Boegehold, M.A.3
  • 105
    • 0035572795 scopus 로고    scopus 로고
    • NO modulates monocyte chemotactic protein-1 expression in endothelial cells under cyclic strain
    • Wung B.S., Cheng J.J., Shyue S.K., Wang D.L. NO modulates monocyte chemotactic protein-1 expression in endothelial cells under cyclic strain. Arterioscler. Thromb. Vasc. Biol. 21:2001;1941-1947
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 1941-1947
    • Wung, B.S.1    Cheng, J.J.2    Shyue, S.K.3    Wang, D.L.4
  • 106
    • 0343048978 scopus 로고    scopus 로고
    • Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation
    • Wagner A.H., Kohler T., Ruckschloss U., Just I., Hecker M. Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation. Arterioscler. Thromb. Vasc. Biol. 20:2000;61-69
    • (2000) Arterioscler. Thromb. Vasc. Biol. , vol.20 , pp. 61-69
    • Wagner, A.H.1    Kohler, T.2    Ruckschloss, U.3    Just, I.4    Hecker, M.5
  • 108
    • 0032508533 scopus 로고    scopus 로고
    • Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
    • Laufs U., Liao J.K. Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase. J. Biol. Chem. 273:1998;24266-24271
    • (1998) J. Biol. Chem. , vol.273 , pp. 24266-24271
    • Laufs, U.1    Liao, J.K.2
  • 109
    • 0032555154 scopus 로고    scopus 로고
    • Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase
    • Endres M., Laufs U., Huang Z., Nakamura T., Huang P., Moskowitz M.A., et al. Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase. Proc. Natl. Acad. Sci. USA. 95:1998;8880-8885
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8880-8885
    • Endres, M.1    Laufs, U.2    Huang, Z.3    Nakamura, T.4    Huang, P.5    Moskowitz, M.A.6
  • 110
    • 0035569562 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species
    • Wassmann S., Laufs U., Baumer A.T., Muller K., Ahlbory K., Linz W., et al. HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species. Hypertension. 37:2001;1450-1457
    • (2001) Hypertension , vol.37 , pp. 1450-1457
    • Wassmann, S.1    Laufs, U.2    Baumer, A.T.3    Muller, K.4    Ahlbory, K.5    Linz, W.6
  • 111
    • 0036481621 scopus 로고    scopus 로고
    • Policosanol: Clinical pharmacology and therapeutic significance of a new lipid-lowering agent
    • Gouni-Berthold I., Berthold H.K. Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent. Am. Heart J. 143:2002;356-365
    • (2002) Am. Heart J. , vol.143 , pp. 356-365
    • Gouni-Berthold, I.1    Berthold, H.K.2
  • 113
    • 0034811899 scopus 로고    scopus 로고
    • 17beta-estradiol inhibition of NADPH oxidase expression in human endothelial cells
    • Wagner A.H., Schroeter M.R., Hecker M. 17beta-estradiol inhibition of NADPH oxidase expression in human endothelial cells. FASEB J. 15:2001;2121-2130
    • (2001) FASEB J. , vol.15 , pp. 2121-2130
    • Wagner, A.H.1    Schroeter, M.R.2    Hecker, M.3
  • 114
    • 0036178170 scopus 로고    scopus 로고
    • In vivo evidence for antioxidant potential of estrogen in microvessels of female spontaneously hypertensive rats
    • Dantas A.P., Tostes R.C., Fortes Z.B., Costa S.G., Nigro D., Carvalho M.H. In vivo evidence for antioxidant potential of estrogen in microvessels of female spontaneously hypertensive rats. Hypertension. 39:2002;405-411
    • (2002) Hypertension , vol.39 , pp. 405-411
    • Dantas, A.P.1    Tostes, R.C.2    Fortes, Z.B.3    Costa, S.G.4    Nigro, D.5    Carvalho, M.H.6
  • 115
    • 0037197781 scopus 로고    scopus 로고
    • Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production
    • Wassmann S., Laufs U., Stamenkovic D., Linz W., Stasch J.P., Ahlbory K., et al. Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production. Circulation. 105:2002;2083-2091
    • (2002) Circulation , vol.105 , pp. 2083-2091
    • Wassmann, S.1    Laufs, U.2    Stamenkovic, D.3    Linz, W.4    Stasch, J.P.5    Ahlbory, K.6
  • 116
    • 0034123656 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase and estrogen
    • Kappagoda C.T. Endothelial nitric oxide synthase and estrogen. Cardiovasc. Res. 47:2000;9-10
    • (2000) Cardiovasc. Res. , vol.47 , pp. 9-10
    • Kappagoda, C.T.1
  • 117
    • 0034044808 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase activity in aorta of normocholesterolemic rabbits: Regional variation and the effect of estrogen
    • Andersen M.R., Stender S. Endothelial nitric oxide synthase activity in aorta of normocholesterolemic rabbits: regional variation and the effect of estrogen. Cardiovasc. Res. 47:2000;192-199
    • (2000) Cardiovasc. Res. , vol.47 , pp. 192-199
    • Andersen, M.R.1    Stender, S.2
  • 118
    • 0036284248 scopus 로고    scopus 로고
    • Estrogen increases endothelial nitric oxide synthase via estrogen receptors in rat cerebral blood vessels: Effect preserved after concurrent treatment with medroxyprogesterone acetate or progesterone
    • McNeill A.M., Zhang C., Stanczyk F.Z., Duckles S.P., Krause D.N. Estrogen increases endothelial nitric oxide synthase via estrogen receptors in rat cerebral blood vessels: effect preserved after concurrent treatment with medroxyprogesterone acetate or progesterone. Stroke. 33:2002;1685-1691
    • (2002) Stroke , vol.33 , pp. 1685-1691
    • McNeill, A.M.1    Zhang, C.2    Stanczyk, F.Z.3    Duckles, S.P.4    Krause, D.N.5
  • 119
    • 0035991932 scopus 로고    scopus 로고
    • Chronic exercise increases both inducible and endothelial nitric oxide synthase gene expression in endothelial cells of rat aorta
    • Yang A.L., Tsai S.J., Jiang M.J., Jen C.J., Chen H. Chronic exercise increases both inducible and endothelial nitric oxide synthase gene expression in endothelial cells of rat aorta. J. Biomed. Sci. 9:2002;149-155
    • (2002) J. Biomed. Sci. , vol.9 , pp. 149-155
    • Yang, A.L.1    Tsai, S.J.2    Jiang, M.J.3    Jen, C.J.4    Chen, H.5
  • 120
    • 0029819441 scopus 로고    scopus 로고
    • Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow
    • Nadaud S., Philippe M., Arnal J.F., Michel J.B., Soubrier F. Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow. Circ. Res. 79:1996;857-863
    • (1996) Circ. Res. , vol.79 , pp. 857-863
    • Nadaud, S.1    Philippe, M.2    Arnal, J.F.3    Michel, J.B.4    Soubrier, F.5
  • 121
    • 0030925802 scopus 로고    scopus 로고
    • Shear stress induction of the endothelial nitric oxide synthase gene is calcium-dependent but not calcium-activated
    • Xiao Z., Zhang Z., Ranjan V., Diamond S.L. Shear stress induction of the endothelial nitric oxide synthase gene is calcium-dependent but not calcium-activated. J. Cell. Physiol. 171:1997;205-211
    • (1997) J. Cell. Physiol. , vol.171 , pp. 205-211
    • Xiao, Z.1    Zhang, Z.2    Ranjan, V.3    Diamond, S.L.4
  • 122
    • 0034022357 scopus 로고    scopus 로고
    • Unidirectional and oscillatory shear stress differentially modulate NOS III gene expression
    • Silacci P., Formentin K., Bouzourene K., Daniel F., Brunner H.R., Hayoz D. Unidirectional and oscillatory shear stress differentially modulate NOS III gene expression. Nitric Oxide. 4:2000;47-56
    • (2000) Nitric Oxide , vol.4 , pp. 47-56
    • Silacci, P.1    Formentin, K.2    Bouzourene, K.3    Daniel, F.4    Brunner, H.R.5    Hayoz, D.6
  • 123
    • 0035941411 scopus 로고    scopus 로고
    • Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways
    • Davis M.E., Cai H., Drummond G.R., Harrison D.G. Shear stress regulates endothelial nitric oxide synthase expression through c-Src by divergent signaling pathways. Circ. Res. 89:2001;1073-1080
    • (2001) Circ. Res. , vol.89 , pp. 1073-1080
    • Davis, M.E.1    Cai, H.2    Drummond, G.R.3    Harrison, D.G.4
  • 124
    • 0033830973 scopus 로고    scopus 로고
    • Modulation of vascular endothelial gene expression by physical training in patients with chronic heart failure
    • Testa M., Ennezat P.V., Vikstrom K.L., Demopoulos L., Gentilucci M., Loperfido F., et al. Modulation of vascular endothelial gene expression by physical training in patients with chronic heart failure. Ital. Heart J. 1:2000;426-430
    • (2000) Ital. Heart J. , vol.1 , pp. 426-430
    • Testa, M.1    Ennezat, P.V.2    Vikstrom, K.L.3    Demopoulos, L.4    Gentilucci, M.5    Loperfido, F.6
  • 125
    • 0035909016 scopus 로고    scopus 로고
    • Endothelium-mediated relaxation of porcine collateral-dependent arterioles is improved by exercise training
    • Griffin K.L., Woodman C.R., Price E.M., Laughlin M.H., Parker J.L. Endothelium-mediated relaxation of porcine collateral-dependent arterioles is improved by exercise training. Circulation. 104:2001;1393-1398
    • (2001) Circulation , vol.104 , pp. 1393-1398
    • Griffin, K.L.1    Woodman, C.R.2    Price, E.M.3    Laughlin, M.H.4    Parker, J.L.5
  • 126
    • 0034842684 scopus 로고    scopus 로고
    • Effects of exercise training on vascular function and myocardial perfusion
    • Gielen S., Hambrecht R. Effects of exercise training on vascular function and myocardial perfusion. Cardiol. Clin. 19:2001;357-368
    • (2001) Cardiol. Clin. , vol.19 , pp. 357-368
    • Gielen, S.1    Hambrecht, R.2
  • 127
    • 0027233868 scopus 로고
    • Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life
    • Yoshizumi M., Perrella M.A., Burnett J.C.J., Lee M.E. Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. Circ. Res. 73:1993;205-209
    • (1993) Circ. Res. , vol.73 , pp. 205-209
    • Yoshizumi, M.1    Perrella, M.A.2    Burnett, J.C.J.3    Lee, M.E.4
  • 128
    • 1842373296 scopus 로고    scopus 로고
    • Endothelial cytosolic proteins bind to the 3' untranslated region of endothelial nitric oxide synthase mRNA: Regulation by tumor necrosis factor alpha
    • Alonso J., Sanchez dM, Monton M., Casado S., Lopez-Farre A. Endothelial cytosolic proteins bind to the 3' untranslated region of endothelial nitric oxide synthase mRNA: regulation by tumor necrosis factor alpha. Mol. Cell. Biol. 17:1997;5719-5726
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5719-5726
    • Alonso, J.1    Dm, S.2    Monton, M.3    Casado, S.4    Lopez-Farre, A.5
  • 129
    • 0035112980 scopus 로고    scopus 로고
    • Cerivastatin prevents tumor necrosis factor-alpha-induced downregulation of endothelial nitric oxide synthase: Role of endothelial cytosolic proteins
    • Gonzalez-Fernandez F., Jimenez A., Lopez-Blaya A., Velasco S., Arriero M.M., Celdran A., et al. Cerivastatin prevents tumor necrosis factor-alpha-induced downregulation of endothelial nitric oxide synthase: role of endothelial cytosolic proteins. Atherosclerosis. 155:2001;61-70
    • (2001) Atherosclerosis , vol.155 , pp. 61-70
    • Gonzalez-Fernandez, F.1    Jimenez, A.2    Lopez-Blaya, A.3    Velasco, S.4    Arriero, M.M.5    Celdran, A.6
  • 130
    • 0034651949 scopus 로고    scopus 로고
    • Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: A specific vascular action of insulin
    • Kuboki K., Jiang Z.Y., Takahara N., Ha S.W., Igarashi M., Yamauchi T., et al. Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo: a specific vascular action of insulin. Circulation. 101:2000;676-681
    • (2000) Circulation , vol.101 , pp. 676-681
    • Kuboki, K.1    Jiang, Z.Y.2    Takahara, N.3    Ha, S.W.4    Igarashi, M.5    Yamauchi, T.6
  • 131
    • 0033950472 scopus 로고    scopus 로고
    • Effect of insulin on human aortic endothelial nitric oxide synthase
    • Aljada A., Dandona P. Effect of insulin on human aortic endothelial nitric oxide synthase. Metabolism. 49:2000;147-150
    • (2000) Metabolism , vol.49 , pp. 147-150
    • Aljada, A.1    Dandona, P.2
  • 132
    • 0033867239 scopus 로고    scopus 로고
    • Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression
    • Ding Y., Vaziri N.D., Coulson R., Kamanna V.S., Roh D.D. Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression. Am. J. Physiol. Endocrinol. Metab. 279:2000;E11-E17
    • (2000) Am. J. Physiol. Endocrinol. Metab. , vol.279
    • Ding, Y.1    Vaziri, N.D.2    Coulson, R.3    Kamanna, V.S.4    Roh, D.D.5
  • 133
    • 0025301338 scopus 로고
    • Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential
    • Luckhoff A., Busse R. Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential. Pflugers Arch. 416:1990;305-311
    • (1990) Pflugers Arch. , vol.416 , pp. 305-311
    • Luckhoff, A.1    Busse, R.2
  • 135
    • 0035839532 scopus 로고    scopus 로고
    • Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser (1179
    • Montagnani M., Chen H., Barr V.A., Quon M.J. Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser (1179. J. Biol. Chem. 276:2001;30392-30398
    • (2001) J. Biol. Chem. , vol.276 , pp. 30392-30398
    • Montagnani, M.1    Chen, H.2    Barr, V.A.3    Quon, M.J.4
  • 136
    • 0037166321 scopus 로고    scopus 로고
    • Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli
    • Lane P., Gross S.S. Disabling a C-terminal autoinhibitory control element in endothelial nitric-oxide synthase by phosphorylation provides a molecular explanation for activation of vascular NO synthesis by diverse physiological stimuli. J. Biol. Chem. 277:2002;19087-19094
    • (2002) J. Biol. Chem. , vol.277 , pp. 19087-19094
    • Lane, P.1    Gross, S.S.2
  • 137
    • 0036479305 scopus 로고    scopus 로고
    • Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser 1179 by Akt-independent mechanisms: Role of protein kinase a
    • Boo Y.C., Sorescu G., Boyd N., Shiojima I., Walsh K., Du J., et al. Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser 1179 by Akt-independent mechanisms: role of protein kinase A. J. Biol. Chem. 277:2002;3388-3396
    • (2002) J. Biol. Chem. , vol.277 , pp. 3388-3396
    • Boo, Y.C.1    Sorescu, G.2    Boyd, N.3    Shiojima, I.4    Walsh, K.5    Du, J.6
  • 139
    • 0030454148 scopus 로고    scopus 로고
    • Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. a double-blind, placebo-controlled study
    • Boger R.H., Skamira C., Bode-Boger S.M., Brabant G., Von Zur M., Frolich J.C. Nitric oxide may mediate the hemodynamic effects of recombinant growth hormone in patients with acquired growth hormone deficiency. A double-blind, placebo-controlled study. J. Clin. Invest. 98:1996;2706-2713
    • (1996) J. Clin. Invest. , vol.98 , pp. 2706-2713
    • Boger, R.H.1    Skamira, C.2    Bode-Boger, S.M.3    Brabant, G.4    Von Zur, M.5    Frolich, J.C.6
  • 140
    • 0032602417 scopus 로고    scopus 로고
    • Nitric oxide and the mediation of the hemodynamic effects of growth hormone in humans
    • Boger R.H. Nitric oxide and the mediation of the hemodynamic effects of growth hormone in humans. J. Endocrinol. Invest. 22:1999;75-81
    • (1999) J. Endocrinol. Invest. , vol.22 , pp. 75-81
    • Boger, R.H.1
  • 141
    • 0028290478 scopus 로고
    • Intracellular alkalinization induced by bradykinin sustains activation of the constitutive nitric oxide synthase in endothelial cells
    • Fleming I., Hecker M., Busse R. Intracellular alkalinization induced by bradykinin sustains activation of the constitutive nitric oxide synthase in endothelial cells. Circ. Res. 74:1994;1220-1226
    • (1994) Circ. Res. , vol.74 , pp. 1220-1226
    • Fleming, I.1    Hecker, M.2    Busse, R.3
  • 142
    • 0029914567 scopus 로고    scopus 로고
    • Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells [see comments]
    • Ayajiki K., Kindermann M., Hecker M., Fleming I., Busse R. Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells [see comments]. Circ. Res. 78:1996;750-758
    • (1996) Circ. Res. , vol.78 , pp. 750-758
    • Ayajiki, K.1    Kindermann, M.2    Hecker, M.3    Fleming, I.4    Busse, R.5
  • 145
    • 0030722166 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilatation and total body nitric oxide production in healthy old age
    • Lyons D., Roy S., Patel M., Benjamin N., Swift C.G. Impaired nitric oxide-mediated vasodilatation and total body nitric oxide production in healthy old age. Clin. Sci. (Lond.). 93:1997;519-525
    • (1997) Clin. Sci. (Lond.) , vol.93 , pp. 519-525
    • Lyons, D.1    Roy, S.2    Patel, M.3    Benjamin, N.4    Swift, C.G.5
  • 146
    • 0034720839 scopus 로고    scopus 로고
    • Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes
    • Taddei S., Galetta F., Virdis A., Ghiadoni L., Salvetti G., Franzoni F., et al. Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation. 101:2000;2896-2901
    • (2000) Circulation , vol.101 , pp. 2896-2901
    • Taddei, S.1    Galetta, F.2    Virdis, A.3    Ghiadoni, L.4    Salvetti, G.5    Franzoni, F.6
  • 147
    • 0036257720 scopus 로고    scopus 로고
    • Ageing is associated with impairment of nitric oxide and prostanoid dilator pathways in the human forearm
    • Singh N., Prasad S., Singer D.R., MacAllister R.J. Ageing is associated with impairment of nitric oxide and prostanoid dilator pathways in the human forearm. Clin. Sci. (Lond.). 102:2002;595-600
    • (2002) Clin. Sci. (Lond.) , vol.102 , pp. 595-600
    • Singh, N.1    Prasad, S.2    Singer, D.R.3    MacAllister, R.J.4
  • 148
    • 0037076784 scopus 로고    scopus 로고
    • Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function
    • Csiszar A., Ungvari Z., Edwards J.G., Kaminski P., Wolin M.S., Koller A., et al. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ. Res. 90:2002;1159-1166
    • (2002) Circ. Res. , vol.90 , pp. 1159-1166
    • Csiszar, A.1    Ungvari, Z.2    Edwards, J.G.3    Kaminski, P.4    Wolin, M.S.5    Koller, A.6
  • 149
    • 0035955754 scopus 로고    scopus 로고
    • ENOS activity is reduced in senescent human endothelial cells: Preservation by hTERT immortalization
    • Matsushita H., Chang E., Glassford A.J., Cooke J.P., Chiu C.P., Tsao P.S. eNOS activity is reduced in senescent human endothelial cells: preservation by hTERT immortalization. Circ. Res. 89:2001;793-798
    • (2001) Circ. Res. , vol.89 , pp. 793-798
    • Matsushita, H.1    Chang, E.2    Glassford, A.J.3    Cooke, J.P.4    Chiu, C.P.5    Tsao, P.S.6
  • 150
    • 0037007075 scopus 로고    scopus 로고
    • Endothelial cell senescence in human atherosclerosis: Role of telomere in endothelial dysfunction
    • Minamino T., Miyauchi H., Yoshida T., Ishida Y., Yoshida H., Komuro I. Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation. 105:2002;1541-1544
    • (2002) Circulation , vol.105 , pp. 1541-1544
    • Minamino, T.1    Miyauchi, H.2    Yoshida, T.3    Ishida, Y.4    Yoshida, H.5    Komuro, I.6
  • 153
    • 0037076784 scopus 로고    scopus 로고
    • Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function
    • Csiszar A., Ungvari Z., Edwards J.G., Kaminski P., Wolin M.S., Koller A., et al. Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ. Res. 90:2002;1159-1166
    • (2002) Circ. Res. , vol.90 , pp. 1159-1166
    • Csiszar, A.1    Ungvari, Z.2    Edwards, J.G.3    Kaminski, P.4    Wolin, M.S.5    Koller, A.6
  • 154
    • 8444220845 scopus 로고    scopus 로고
    • Optimizing endothelial nitric oxide production may slow endothelial aging
    • (in press)
    • McCarty MF. Optimizing endothelial nitric oxide production may slow endothelial aging. Med. Hypotheses; 2002 (in press)
    • (2002) Med. Hypotheses
    • McCarty, M.F.1
  • 155
    • 0028305415 scopus 로고
    • Adverse effects of increased dietary folate. Relation to measures to reduce the incidence of neural tube defects
    • Chanarin I. Adverse effects of increased dietary folate. Relation to measures to reduce the incidence of neural tube defects. Clin. Invest. Med. 17:1994;244-252
    • (1994) Clin. Invest. Med. , vol.17 , pp. 244-252
    • Chanarin, I.1
  • 157
    • 0029067620 scopus 로고
    • Does folic acid harm people with vitamin B12 deficiency?
    • Dickinson C.J. Does folic acid harm people with vitamin B12 deficiency? QJM. 88:1995;357-364
    • (1995) QJM , vol.88 , pp. 357-364
    • Dickinson, C.J.1
  • 158
    • 0014343018 scopus 로고
    • Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor
    • Berlin H., Berlin R., Brante G. Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor. Acta Med. Scand. 184:1968;247-258
    • (1968) Acta Med. Scand. , vol.184 , pp. 247-258
    • Berlin, H.1    Berlin, R.2    Brante, G.3
  • 159
    • 0025977057 scopus 로고
    • Oral cobalamin for pernicious anemia. Medicine's best kept secret?
    • Lederle F.A. Oral cobalamin for pernicious anemia. Medicine's best kept secret? JAMA. 265:1991;94-95
    • (1991) JAMA , vol.265 , pp. 94-95
    • Lederle, F.A.1
  • 160
    • 0025964965 scopus 로고
    • Oral cobalamin for treatment of pernicious anemia?
    • Hathcock J.N., Troendle G.J. Oral cobalamin for treatment of pernicious anemia? JAMA. 265:1991;96-97
    • (1991) JAMA , vol.265 , pp. 96-97
    • Hathcock, J.N.1    Troendle, G.J.2


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