메뉴 건너뛰기




Volumn 51, Issue 6, 2011, Pages 913-925

Links between electrophysiological and molecular pathology of amyotrophic lateral sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM BINDING PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMIC ACID; SUPEROXIDE DISMUTASE;

EID: 82255181339     PISSN: 15407063     EISSN: 15577023     Source Type: Journal    
DOI: 10.1093/icb/icr116     Document Type: Conference Paper
Times cited : (27)

References (167)
  • 4
    • 0035833937 scopus 로고    scopus 로고
    • Immune reactivity in a mouse model of familial ALS correlates with disease progression
    • Alexianu ME, Kozovska M, Appel SH. 2001. Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57:1282-9. (Pubitemid 32947389)
    • (2001) Neurology , vol.57 , Issue.7 , pp. 1282-1289
    • Alexianu, M.E.1    Kozovska, M.2    Appel, S.H.3
  • 5
    • 58149169031 scopus 로고    scopus 로고
    • Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice
    • Amendola J, Durand J. 2008. Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice. J Comp Neurol 511:329-41.
    • (2008) J Comp Neurol , vol.511 , pp. 329-41
    • Amendola, J.1    Durand, J.2
  • 6
    • 9644257278 scopus 로고    scopus 로고
    • Altered sensorimotor development in a transgenic mouse model of amyotrophic lateral sclerosis
    • DOI 10.1111/j.1460-9568.2004.03745.x
    • Amendola J, Verrier B, Roubertoux P, Durand J. 2004. Altered sensorimotor development in a transgenic mouse model of amyotrophic lateral sclerosis. Eur J Neurosci 20:2822-6. (Pubitemid 39573798)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.10 , pp. 2822-2826
    • Amendola, J.1    Verrier, B.2    Roubertoux, P.3    Durand, J.4
  • 7
    • 0034698248 scopus 로고    scopus 로고
    • Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes
    • DOI 10.1016/S0006-8993(00)02430-6, PII S0006899300024306
    • Azbill RD, Mu X, Springer JE. 2000. Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes. Brain Res 871:175-80. (Pubitemid 30433869)
    • (2000) Brain Research , vol.871 , Issue.2 , pp. 175-180
    • Azbill, R.D.1    Mu, X.2    Springer, J.E.3
  • 8
    • 0029014109 scopus 로고
    • Inhibition of N- and P-type calcium currents and the afterhyperpolarization in rat motoneurones by serotonin
    • Bayliss DA, Umemiya M, Berger AJ. 1995. Inhibition of N- and P-type calcium currents and the afterhyperpolarization in rat motoneurones by serotonin. J Physiol 485:635-47.
    • (1995) J Physiol , vol.485 , pp. 635-47
    • Bayliss, D.A.1    Umemiya, M.2    Berger, A.J.3
  • 10
    • 78751515661 scopus 로고    scopus 로고
    • A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: What have we learned in the last decade?
    • Bellingham MC. 2011. A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?. CNS Neurosci Ther 17:4-31.
    • (2011) CNS Neurosci Ther , vol.17 , pp. 4-31
    • Bellingham, M.C.1
  • 12
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • DOI 10.1056/NEJM199403033300901
    • Bensimon G, Lacomblez L, Meininger V. 1994. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/ Riluzole Study Group. N Engl J Med 330:585-91. (Pubitemid 24065791)
    • (1994) New England Journal of Medicine , vol.330 , Issue.9 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 13
    • 1542346966 scopus 로고    scopus 로고
    • 2+ levels in brainstem motoneurones from mouse
    • DOI 10.1113/jphysiol.2003.053900
    • Bergmann F, Keller BU. 2004. Impact of mitochondrial inhibition on excitability and cytosolic Ca2+ levels in brainstem motoneurones from mouse. J Physiol 555:45-59. (Pubitemid 38324500)
    • (2004) Journal of Physiology , vol.555 , Issue.1 , pp. 45-59
    • Bergmann, F.1    Keller, B.U.2
  • 14
    • 79954423426 scopus 로고    scopus 로고
    • ERAD and ERAD tuning: Disposal of cargo and of ERAD regulators from the mammalian ER
    • Bernasconi R, Molinari M. 2011. ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER. Curr Opin Cell Biol 23:176-83.
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 176-83
    • Bernasconi, R.1    Molinari, M.2
  • 15
    • 55849091446 scopus 로고    scopus 로고
    • Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria
    • Bilsland LG, Nirmalananthan N, Yip J, Greensmith L, Duchen MR. 2008. Expression of mutant SOD1 in astrocytes induces functional deficits in motoneuron mitochondria. J Neurochem 107:1271-83.
    • (2008) J Neurochem , vol.107 , pp. 1271-83
    • Bilsland, L.G.1    Nirmalananthan, N.2    Yip, J.3    Greensmith, L.4    Duchen, M.R.5
  • 17
    • 78650962524 scopus 로고    scopus 로고
    • Deconstruction for reconstruction: The role of proteolysis in neural plasticity and disease
    • Bingol B, Sheng M. 2011. Deconstruction for reconstruction: the role of proteolysis in neural plasticity and disease. Neuron 69:22-32.
    • (2011) Neuron , vol.69 , pp. 22-32
    • Bingol, B.1    Sheng, M.2
  • 18
    • 72849106974 scopus 로고    scopus 로고
    • Mechanisms underlying spontaneous patterned activity in developing neural circuits
    • Blankenship AG, Feller MB. 2010. Mechanisms underlying spontaneous patterned activity in developing neural circuits. Nat Rev Neurosci 11:18-29.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 18-29
    • Blankenship, A.G.1    Feller, M.B.2
  • 20
    • 33847017739 scopus 로고    scopus 로고
    • Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis
    • Bories C, Amendola J, Lamotte d'Incamps B, Durand J. 2007. Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis. Eur J Neurosci 25:451-9.
    • (2007) Eur J Neurosci , vol.25 , pp. 451-9
    • Bories, C.1    Amendola, J.2    Lamotte D'incamps, B.3    Durand, J.4
  • 25
    • 77957781372 scopus 로고    scopus 로고
    • Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture
    • Carunchio I, Curcio L, Pieri M, Pica F, Caioli S, Viscomi MT, Molinari M, Canu N, Bernardi G, Zona C. 2010. Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture. Exp Neurol 226:218-30.
    • (2010) Exp Neurol , vol.226 , pp. 218-30
    • Carunchio, I.1    Curcio, L.2    Pieri, M.3    Pica, F.4    Caioli, S.5    Viscomi, M.T.6    Molinari, M.7    Canu, N.8    Bernardi, G.9    Zona, C.10
  • 26
    • 35448970057 scopus 로고    scopus 로고
    • Serotonin stimulates mitochondrial transport in hippocampal neurons
    • DOI 10.1016/j.mcn.2007.08.004, PII S1044743107001807
    • Chen S, Owens GC, Crossin KL, Edelman DB. 2007. Serotonin stimulates mitochondrial transport in hippocampal neurons. Mol Cell Neurosci 36:472-83. (Pubitemid 47633971)
    • (2007) Molecular and Cellular Neuroscience , vol.36 , Issue.4 , pp. 472-483
    • Chen, S.1    Owens, G.C.2    Crossin, K.L.3    Edelman, D.B.4
  • 27
    • 50949084911 scopus 로고    scopus 로고
    • Dopamine inhibits mitochondrial motility in hippocampal neurons
    • Chen S, Owens GC, Edelman DB. 2008. Dopamine inhibits mitochondrial motility in hippocampal neurons. PLoS One 3:e2804.
    • (2008) PLoS One , vol.3
    • Chen, S.1    Owens, G.C.2    Edelman, D.B.3
  • 31
    • 0027946294 scopus 로고
    • Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis
    • Dal Canto MC, Gurney ME. 1994. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am J Pathol 145:1271-9. (Pubitemid 24378480)
    • (1994) American Journal of Pathology , vol.145 , Issue.6 , pp. 1271-1279
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 32
    • 0028933344 scopus 로고
    • Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
    • Dal Canto MC, Gurney ME. 1995. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 676:25-40.
    • (1995) Brain Res , vol.676 , pp. 25-40
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 33
    • 33645102302 scopus 로고    scopus 로고
    • Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice
    • Damiano M, Starkov AA, Petri S, Kipiani K, Kiaei M, Mattiazzi M, Flint Beal M, Manfredi G. 2006. Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice. J Neurochem 96:1349-61.
    • (2006) J Neurochem , vol.96 , pp. 1349-61
    • Damiano, M.1    Starkov, A.A.2    Petri, S.3    Kipiani, K.4    Kiaei, M.5    Mattiazzi, M.6    Flint Beal, M.7    Manfredi, G.8
  • 37
    • 57049111544 scopus 로고    scopus 로고
    • Dendrite elongation and dendritic branching are affected separately by different forms of intrinsic motoneuron excitability
    • Duch C, Vonhoff F, Ryglewski S. 2008. Dendrite elongation and dendritic branching are affected separately by different forms of intrinsic motoneuron excitability. J Neurophysiol 100:2525-36.
    • (2008) J Neurophysiol , vol.100 , pp. 2525-36
    • Duch, C.1    Vonhoff, F.2    Ryglewski, S.3
  • 38
    • 77951615746 scopus 로고    scopus 로고
    • Evidence from computer simulations for alterations in the membrane biophysical properties and dendritic processing of synaptic inputs in mutant superoxide dismutase-1 motoneurons
    • Elbasiouny SM, Amendola J, Durand J, Heckman CJ. 2010. Evidence from computer simulations for alterations in the membrane biophysical properties and dendritic processing of synaptic inputs in mutant superoxide dismutase-1 motoneurons. J Neurosci 30:5544-58.
    • (2010) J Neurosci , vol.30 , pp. 5544-58
    • Elbasiouny, S.M.1    Amendola, J.2    Durand, J.3    Heckman, C.J.4
  • 39
    • 0029958287 scopus 로고    scopus 로고
    • High endogenous calcium buffering in Purkinje cells from rat cerebellar slices
    • Fierro L, Llano I. 1996. High endogenous calcium buffering in Purkinje cells from rat cerebellar slices. J Physiol 496(Pt 3):617-25. (Pubitemid 26387847)
    • (1996) Journal of Physiology , vol.496 , Issue.3 , pp. 617-625
    • Fierro, L.1    Llano, I.2
  • 41
    • 0034175513 scopus 로고    scopus 로고
    • Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases
    • Frey D, Schneider C, Xu L, Borg J, Spooren W, Caroni P. 2000. Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases. J Neurosci 20:2534-42. (Pubitemid 30220340)
    • (2000) Journal of Neuroscience , vol.20 , Issue.7 , pp. 2534-2542
    • Frey, D.1    Schneider, C.2    Xu, L.3    Borg, J.4    Spooren, W.5    Caroni, P.6
  • 42
    • 32344437345 scopus 로고    scopus 로고
    • Spontaneous network activity in the embryonic spinal cord regulates AMPAergic and GABAergic synaptic strength
    • DOI 10.1016/j.neuron.2006.01.017, PII S0896627306000468
    • Gonzalez-Islas C, Wenner P. 2006. Spontaneous network activity in the embryonic spinal cord regulates AMPAergic and GABAergic synaptic strength. Neuron 49:563-75. (Pubitemid 43221891)
    • (2006) Neuron , vol.49 , Issue.4 , pp. 563-575
    • Gonzalez-Islas, C.1    Wenner, P.2
  • 44
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • DOI 10.1002/ana.410390203
    • Gurney ME, Cutting FB, Zhai P, Doble A, Taylor CP, Andrus PK, Hall ED. 1996. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 39:147-57. (Pubitemid 26071564)
    • (1996) Annals of Neurology , vol.39 , Issue.2 , pp. 147-157
    • Gurney, M.E.1    Cutting, F.B.2    Zhai, P.3    Doble, A.4    Taylor, C.P.5    Andrus, P.K.6    Hall, E.D.7
  • 46
    • 0028365121 scopus 로고
    • Block of the rat brain IIA sodium channel α subunit by the neuroprotective drug riluzole
    • Hebert T, Drapeau P, Pradier L, Dunn RJ. 1994. Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole. Mol Pharmacol 45:1055-60. (Pubitemid 24155800)
    • (1994) Molecular Pharmacology , vol.45 , Issue.5 , pp. 1055-1060
    • Hebert, T.1    Drapeau, P.2    Pradier, L.3    Dunn, R.J.4
  • 47
    • 43049143860 scopus 로고    scopus 로고
    • Persistent inward currents in spinal motoneurons and their influence on human motoneuron firing patterns
    • DOI 10.1177/1073858408314986
    • Heckman CJ, Johnson M, Mottram C, Schuster J. 2008. Persistent inward currents in spinal motoneurons and their influence on human motoneuron firing patterns. Neuroscientist 14:264-75. (Pubitemid 351624860)
    • (2008) Neuroscientist , vol.14 , Issue.3 , pp. 264-275
    • Heckman, C.J.1    Johnson, M.2    Mottram, C.3    Schuster, J.4
  • 48
  • 49
    • 35349025311 scopus 로고    scopus 로고
    • G93A mouse model of amyotrophic lateral sclerosis
    • DOI 10.1016/j.nbd.2007.07.003, PII S0969996107001416
    • Hegedus J, Putman CT, Gordon T. 2007. Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. Neurobiol Dis 28:154-64. (Pubitemid 47615455)
    • (2007) Neurobiology of Disease , vol.28 , Issue.2 , pp. 154-164
    • Hegedus, J.1    Putman, C.T.2    Gordon, T.3
  • 50
    • 48949120504 scopus 로고    scopus 로고
    • Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis
    • DOI 10.1113/jphysiol.2007.149286
    • Hegedus J, Putman CT, Tyreman N, Gordon T. 2008. Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis. J Physiol 586:3337-51. (Pubitemid 352003870)
    • (2008) Journal of Physiology , vol.586 , Issue.14 , pp. 3337-3351
    • Hegedus, J.1    Putman, C.T.2    Tyreman, N.3    Gordon, T.4
  • 51
    • 0141864562 scopus 로고    scopus 로고
    • Glutamate and amyloid β-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms
    • Hiruma H, Katakura T, Takahashi S, Ichikawa T, Kawakami T. 2003. Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms. J Neurosci 23:8967-77. (Pubitemid 37210910)
    • (2003) Journal of Neuroscience , vol.23 , Issue.26 , pp. 8967-8977
    • Hiruma, H.1    Katakura, T.2    Takahashi, S.3    Ichikawa, T.4    Kawakami, T.5
  • 52
    • 0023780272 scopus 로고
    • Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan
    • Hounsgaard J, Hultborn H, Jespersen B, Kiehn O. 1988. Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan. J Physiol 405:345-67.
    • (1988) J Physiol , vol.405 , pp. 345-67
    • Hounsgaard, J.1    Hultborn, H.2    Jespersen, B.3    Kiehn, O.4
  • 53
    • 0024319735 scopus 로고
    • Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential
    • Hounsgaard J, Kiehn O. 1989. Serotonin-induced bistability of turtle motoneurones caused by a nifedipinesensitive calcium plateau potential. J Physiol Lond 414:265-82. (Pubitemid 19177302)
    • (1989) Journal of Physiology , vol.414 , pp. 265-282
    • Hounsgaard, J.1    Kiehn, O.2
  • 54
    • 0031845382 scopus 로고    scopus 로고
    • Ionic basis for serotonin-induced bistable membrane properties in guinea pig trigeminal motoneurons
    • Hsiao CF, Del Negro CA, Trueblood PR, Chandler SH. 1998. Ionic basis for serotonin-induced bistable membrane properties in guinea pig trigeminal motoneurons. J Neurophysiol 79:2847-56.
    • (1998) J Neurophysiol , vol.79 , pp. 2847-56
    • Hsiao, C.F.1    Del Negro, C.A.2    Trueblood, P.R.3    Chandler, S.H.4
  • 57
    • 50449101429 scopus 로고    scopus 로고
    • Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
    • Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. 2008. Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proc Natl Acad Sci USA 105:12599-604.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 12599-604
    • Ilieva, H.S.1    Yamanaka, K.2    Malkmus, S.3    Kakinohana, O.4    Yaksh, T.5    Marsala, M.6    Cleveland, D.W.7
  • 59
    • 62149094382 scopus 로고    scopus 로고
    • Cu/Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of mitochondria and perturbs Ca2+ homeostasis in SOD1G93A mice
    • Jaiswal MK, Keller BU. 2009. Cu/Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of mitochondria and perturbs Ca2+ homeostasis in SOD1G93A mice. Mol Pharmacol 75:478-89.
    • (2009) Mol Pharmacol , vol.75 , pp. 478-89
    • Jaiswal, M.K.1    Keller, B.U.2
  • 61
    • 72849120555 scopus 로고    scopus 로고
    • Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis
    • Jiang M, Schuster JE, Fu R, Siddique T, Heckman CJ. 2009. Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis. J Neurosci 29:15031-8.
    • (2009) J Neurosci , vol.29 , pp. 15031-8
    • Jiang, M.1    Schuster, J.E.2    Fu, R.3    Siddique, T.4    Heckman, C.J.5
  • 62
    • 0032821019 scopus 로고    scopus 로고
    • Development of L-type calcium channels and nifedipine-sensitive motor activity in the postnatal mouse spinal cord
    • DOI 10.1046/j.1460-9568.1999.00765.x
    • Jiang Z, Rempel J, Li J, Sawchuk MA, Carlin KP, Brownstone RM. 1999. Development of L-type calcium channels and a nifedipine-sensitive motor activity in the postnatal mouse spinal cord. Eur J Neurosci 11:3481-7. (Pubitemid 29484245)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.10 , pp. 3481-3487
    • Jiang, Z.1    Rempel, J.2    Li, J.3    Sawchuk, M.A.4    Carlin, K.P.5    Brownstone, R.M.6
  • 63
    • 0033749379 scopus 로고    scopus 로고
    • Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
    • Johnston JA, Dalton MJ, Gurney ME, Kopito RR. 2000. Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 97:12571-6.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12571-6
    • Johnston, J.A.1    Dalton, M.J.2    Gurney, M.E.3    Kopito, R.R.4
  • 64
    • 33750057964 scopus 로고    scopus 로고
    • Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis
    • DOI 10.1111/j.1471-4159.2006.04131.x
    • Kaiser M, Maletzki I, Hulsmann S, Holtmann B, Schulz- Schaeffer W, Kirchhoff F, Bahr M, Neusch C. 2006. Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis. J Neurochem 99:900-12. (Pubitemid 44583449)
    • (2006) Journal of Neurochemistry , vol.99 , Issue.3 , pp. 900-912
    • Kaiser, M.1    Maletzki, I.2    Hulsmann, S.3    Holtmann, B.4    Schulz-Schaeffer, W.5    Kirchhoff, F.6    Bahr, M.7    Neusch, C.8
  • 66
    • 28944446370 scopus 로고    scopus 로고
    • Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA
    • DOI 10.1016/j.neures.2005.09.006, PII S0168010205002464
    • Kawahara Y, Sun H, Ito K, Hideyama T, Aoki M, Sobue G, Tsuji S, Kwak S. 2006. Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA. Neurosci Res 54:11-4. (Pubitemid 41785347)
    • (2006) Neuroscience Research , vol.54 , Issue.1 , pp. 11-14
    • Kawahara, Y.1    Sun, H.2    Ito, K.3    Hideyama, T.4    Aoki, M.5    Sobue, G.6    Tsuji, S.7    Kwak, S.8
  • 67
    • 0030741894 scopus 로고    scopus 로고
    • Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells
    • DOI 10.1074/jbc.272.30.18518
    • Kawasaki H, Morooka T, Shimohama S, Kimura J, Hirano T, Gotoh Y, Nishida E. 1997. Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem 272:18518-21. (Pubitemid 27318185)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.30 , pp. 18518-18521
    • Kawasaki, H.1    Morooka, T.2    Shimohama, S.3    Kimura, J.4    Hirano, T.5    Gotoh, Y.6    Nishida, E.7
  • 68
    • 0029658019 scopus 로고    scopus 로고
    • Neuromuscular functicon impairment is not caused by motor neurone loss in FALS mice: An electromyographic study
    • Kennel PF, Finiels F, Revah F, Mallet J. 1996. Neuromuscular function impairment is not caused by motor neurone loss in FALS mice: an electromyographic study. Neuroreport 7:1427-31. (Pubitemid 26281007)
    • (1996) NeuroReport , vol.7 , Issue.8 , pp. 1427-1431
    • Kennel, P.F.1    Finiels, F.2    Revah, F.3    Mallet, J.4
  • 70
    • 40849095841 scopus 로고    scopus 로고
    • Herp enhances ER-associated protein degradation by recruiting ubiquilins
    • Kim TY, Kim E, Yoon SK, Yoon JB. 2008. Herp enhances ER-associated protein degradation by recruiting ubiquilins. Biochem Biophys Res Commun 369:741-6.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 741-6
    • Kim, T.Y.1    Kim, E.2    Yoon, S.K.3    Yoon, J.B.4
  • 71
    • 0032079517 scopus 로고    scopus 로고
    • Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
    • Kong J, Xu Z. 1998. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci 18:3241-50. (Pubitemid 28186017)
    • (1998) Journal of Neuroscience , vol.18 , Issue.9 , pp. 3241-3250
    • Kong, J.1    Xu, Z.2
  • 72
    • 15844431408 scopus 로고    scopus 로고
    • + current and its effect on excitability in motoneurones cultured from mutant SOD1 mice
    • DOI 10.1113/jphysiol.2004.074138
    • Kuo JJ, Siddique T, Fu R, Heckman CJ. 2005. Increased persistent Na+ current and its effect on excitability in motoneurones cultured from mutant SOD1 mice. J Physiol-London 563:843-54. (Pubitemid 40425599)
    • (2005) Journal of Physiology , vol.563 , Issue.3 , pp. 843-854
    • Kuo, J.J.1    Siddique, T.2    Fu, R.3    Heckman, C.J.4
  • 73
    • 15044346521 scopus 로고    scopus 로고
    • Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis
    • DOI 10.1007/s00109-004-0599-z
    • Kwak S, Kawahara Y. 2005. Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis. J Mol Med (Berl) 83:110-20. (Pubitemid 40379299)
    • (2005) Journal of Molecular Medicine , vol.83 , Issue.2 , pp. 110-120
    • Kwak, S.1    Kawahara, Y.2
  • 75
    • 1242292450 scopus 로고    scopus 로고
    • Serotonergic modulation of intracellular calcium dynamics in neonatal hypoglossal motoneurons from mouse
    • DOI 10.1016/j.brainres.2003.10.033
    • Ladewig T, Lalley PM, Keller BU. 2004. Serotonergic modulation of intracellular calcium dynamics in neonatal hypoglossal motoneurons from mouse. Brain Res 1001:1-12. (Pubitemid 38221523)
    • (2004) Brain Research , vol.1001 , Issue.1-2 , pp. 1-12
    • Ladewig, T.1    Lalley, P.M.2    Keller, B.U.3
  • 76
    • 0021286962 scopus 로고
    • Activation patterns of embryonic chick hind limb muscles recorded in ovo and in an isolated spinal cord preparation
    • Landmesser LT, O'Donovan MJ. 1984. Activation patterns of embryonic chick hind limb muscles recorded in ovo and in an isolated spinal cord preparation. J Physiol 347:189-204. (Pubitemid 14058505)
    • (1984) Journal of Physiology , vol.VOL. 347 , pp. 189-204
    • Landmesser, L.T.1    O'Donovan, M.J.2
  • 77
    • 33845313589 scopus 로고    scopus 로고
    • A quantitative regional expression profile of EAAT2 known and novel splice variants reopens the question of aberrant EAAT2 splicing in disease
    • DOI 10.1016/j.neuint.2006.08.014, PII S0197018606002750
    • Lauriat TL, Richler E, McInnes LA. 2007. A quantitative regional expression profile of EAAT2 known and novel splice variants reopens the question of aberrant EAAT2 splicing in disease. Neurochem Int 50:271-80. (Pubitemid 44879685)
    • (2007) Neurochemistry International , vol.50 , Issue.1 , pp. 271-280
    • Lauriat, T.L.1    Richler, E.2    McInnes, L.A.3
  • 78
    • 33847079961 scopus 로고    scopus 로고
    • MTOR pathway as a target in tissue hypertrophy
    • Lee CH, Inoki K, Guan KL. 2007. mTOR pathway as a target in tissue hypertrophy. Annu Rev Pharmacol 47:443-67.
    • (2007) Annu Rev Pharmacol , vol.47 , pp. 443-67
    • Lee, C.H.1    Inoki, K.2    Guan, K.L.3
  • 79
    • 0034682414 scopus 로고    scopus 로고
    • Neurotoxicity induces cleavage of p35 to p25 by calpain
    • DOI 10.1038/35012636
    • Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH. 2000. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 405:360-4. (Pubitemid 30337070)
    • (2000) Nature , vol.405 , Issue.6784 , pp. 360-364
    • Lee, M.-S.1    Kwon, Y.T.2    Li, M.3    Peng, J.4    Friedlander, R.M.5    Tsai, L.-H.6
  • 80
    • 0033021234 scopus 로고    scopus 로고
    • 1 agonist methoxamine
    • Lee RH, Heckman CJ. 1999. Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine. J Neurophysiol 81:2164-74. (Pubitemid 29262550)
    • (1999) Journal of Neurophysiology , vol.81 , Issue.5 , pp. 2164-2174
    • Lee, R.H.1    Heckman, C.J.2
  • 82
    • 33846908702 scopus 로고    scopus 로고
    • Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury
    • DOI 10.1152/jn.00995.2006
    • Li X, Murray K, Harvey PJ, Ballou EW, Bennett DJ. 2007. Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 97:1236-46. (Pubitemid 46239501)
    • (2007) Journal of Neurophysiology , vol.97 , Issue.2 , pp. 1236-1246
    • Li, X.1    Murray, K.2    Harvey, P.J.3    Ballou, E.W.4    Bennett, D.J.5
  • 83
    • 14844320586 scopus 로고    scopus 로고
    • Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity
    • DOI 10.1152/jn.00164.2004
    • Li Y, Li X, Harvey PJ, Bennett DJ. 2004. Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity. J Neurophysiol 92:2694-703. (Pubitemid 40340482)
    • (2004) Journal of Neurophysiology , vol.92 , Issue.5 , pp. 2694-2703
    • Li, Y.1    Li, X.2    Harvey, P.J.3    Bennett, D.J.4
  • 85
    • 0032528992 scopus 로고    scopus 로고
    • Endogenous calcium buffering in motoneurones of the nucleus hypoglossus from mouse
    • DOI 10.1111/j.1469-7793.1998.105bi.x
    • Lips MB, Keller BU. 1998. Endogenous calcium buffering in motoneurones of the nucleus hypoglossus from mouse. J Physiol 511(Pt 1):105-17. (Pubitemid 28421316)
    • (1998) Journal of Physiology , vol.511 , Issue.1 , pp. 105-117
    • Lips, M.B.1    Keller, B.U.2
  • 87
    • 79151485570 scopus 로고    scopus 로고
    • Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses
    • MacAskill AF, Atkin TA, Kittler JT. 2010. Mitochondrial trafficking and the provision of energy and calcium buffering at excitatory synapses. Eur J Neurosci 32:231-40.
    • (2010) Eur J Neurosci , vol.32 , pp. 231-40
    • MacAskill, A.F.1    Atkin, T.A.2    Kittler, J.T.3
  • 89
    • 77956850818 scopus 로고    scopus 로고
    • TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
    • Mackenzie IR, Rademakers R, Neumann M. 2010. TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 9:995-1007.
    • (2010) Lancet Neurol , vol.9 , pp. 995-1007
    • MacKenzie, I.R.1    Rademakers, R.2    Neumann, M.3
  • 90
    • 1642371041 scopus 로고    scopus 로고
    • Altered Expression of the Glutamate Transporter EAAT2b in Neurological Disease
    • DOI 10.1002/ana.20003
    • Maragakis NJ, Dykes-Hoberg M, Rothstein JD. 2004. Altered expression of the glutamate transporter EAAT2b in neurological disease. Ann Neurol 55:469-77. (Pubitemid 38391963)
    • (2004) Annals of Neurology , vol.55 , Issue.4 , pp. 469-477
    • Maragakis, N.J.1    Dykes-Hoberg, M.2    Rothstein, J.D.3
  • 91
    • 13844264524 scopus 로고    scopus 로고
    • Development of central pattern generating circuits
    • DOI 10.1016/j.conb.2005.01.011
    • Marder E, Rehm KJ. 2005. Development of central pattern generating circuits. Curr Opin Neurobiol 15:86-93. (Pubitemid 40249966)
    • (2005) Current Opinion in Neurobiology , vol.15 , Issue.1 , pp. 86-93
    • Marder, E.1    Rehm, K.J.2
  • 94
    • 57049143140 scopus 로고    scopus 로고
    • Mitochondria in neuroplasticity and neurological disorders
    • Mattson MP, Gleichmann M, Cheng A. 2008. Mitochondria in neuroplasticity and neurological disorders. Neuron 60:748-66.
    • (2008) Neuron , vol.60 , pp. 748-66
    • Mattson, M.P.1    Gleichmann, M.2    Cheng, A.3
  • 95
    • 78349252685 scopus 로고    scopus 로고
    • The diversity of calcium sensor proteins in the regulation of neuronal function
    • McCue HV, Haynes LP, Burgoyne RD. 2010. The diversity of calcium sensor proteins in the regulation of neuronal function. Cold Spring Harb Perspect Biol 2:a004085.
    • (2010) Cold Spring Harb Perspect Biol , vol.2
    • McCue, H.V.1    Haynes, L.P.2    Burgoyne, R.D.3
  • 96
    • 78149482855 scopus 로고    scopus 로고
    • Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: Evidence for increased persistent inward currents
    • Meehan CF, Moldovan M, Marklund SL, Graffmo KS, Nielsen JB, Hultborn H. 2010. Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: evidence for increased persistent inward currents. Acta Physiol (Oxf) 200:361-76.
    • (2010) Acta Physiol (Oxf) , vol.200 , pp. 361-76
    • Meehan, C.F.1    Moldovan, M.2    Marklund, S.L.3    Graffmo, K.S.4    Nielsen, J.B.5    Hultborn, H.6
  • 97
    • 0036088327 scopus 로고    scopus 로고
    • Modulation of phrenic motoneuron excitability by ATP: Consequences for respiratory-related output in vitro
    • Miles GB, Parkis MA, Lipski J, Funk GD. 2002. Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro. J Appl Physiol 92:1899-910. (Pubitemid 34666417)
    • (2002) Journal of Applied Physiology , vol.92 , Issue.5 , pp. 1899-1910
    • Miles, G.B.1    Parkis, M.A.2    Lipski, J.3    Funk, G.D.4
  • 99
    • 34147149003 scopus 로고    scopus 로고
    • ADP regulates movements of mitochondria in neurons
    • DOI 10.1529/biophysj.106.092981
    • Mironov SL. 2007. ADP regulates movements of mitochondria in neurons. Biophys J 92:2944-52. (Pubitemid 46557867)
    • (2007) Biophysical Journal , vol.92 , Issue.8 , pp. 2944-2952
    • Mironov, S.L.1
  • 100
    • 0031898458 scopus 로고    scopus 로고
    • Strength-duration properties of sensory and motor axons in amyotrophic lateral sclerosis
    • DOI 10.1093/brain/121.5.851
    • Mogyoros I, Kiernan MC, Burke D, Bostock H. 1998. Strength-duration properties of sensory and motor axons in amyotrophic lateral sclerosis. Brain 121(Pt 5):851-9. (Pubitemid 28220893)
    • (1998) Brain , vol.121 , Issue.5 , pp. 851-859
    • Mogyoros, I.1    Kiernan, M.C.2    Burke, D.3    Bostock, H.4
  • 101
    • 79951552531 scopus 로고    scopus 로고
    • NO orchestrates the loss of synaptic boutons from adult "sick" motoneurons: Modeling a molecular mechanism
    • Moreno-Lopez B, Sunico CR, Gonzalez-Forero D. 2011. NO orchestrates the loss of synaptic boutons from adult "sick" motoneurons: modeling a molecular mechanism. Mol Neurobiol 43:41-66.
    • (2011) Mol Neurobiol , vol.43 , pp. 41-66
    • Moreno-Lopez, B.1    Sunico, C.R.2    Gonzalez-Forero, D.3
  • 103
    • 0036324129 scopus 로고    scopus 로고
    • Alternative splicing of the 5′-sequences of the mouse EAAT2 glutamate transporter and expression in a transgenic model for amyotrophic lateral sclerosis
    • DOI 10.1046/j.1471-4159.2002.01012.x
    • Munch C, Ebstein M, Seefried U, Zhu B, Stamm S, Landwehrmeyer GB, Ludolph AC, Schwalenstocker B, Meyer T. 2002. Alternative splicing of the 5'-sequences of the mouse EAAT2 glutamate transporter and expression in a transgenic model for amyotrophic lateral sclerosis. J Neurochem 82:594-603. (Pubitemid 34831497)
    • (2002) Journal of Neurochemistry , vol.82 , Issue.3 , pp. 594-603
    • Munch, C.1    Ebstein, M.2    Seefried, U.3    Zhu, B.4    Stamm, S.5    Landwehrmeyer, G.B.6    Ludolph, A.C.7    Schwalenstocker, B.8    Meyer, T.9
  • 104
    • 0028357658 scopus 로고
    • Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons
    • Mynlieff M, Beam KG. 1994. Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons. J Neurosci 14:3628-34. (Pubitemid 24174111)
    • (1994) Journal of Neuroscience , vol.14 , Issue.6 , pp. 3628-3634
    • Mynlieff, M.1    Beam, K.G.2
  • 105
    • 34247475338 scopus 로고    scopus 로고
    • Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
    • DOI 10.1038/nn1876, PII NN1876
    • Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S. 2007. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci 10:615-22. (Pubitemid 46652435)
    • (2007) Nature Neuroscience , vol.10 , Issue.5 , pp. 615-622
    • Nagai, M.1    Re, D.B.2    Nagata, T.3    Chalazonitis, A.4    Jessell, T.M.5    Wichterle, H.6    Przedborski, S.7
  • 106
    • 0028784222 scopus 로고
    • The use of fura-2 for estimating Ca buffers and Ca fluxes
    • Neher E. 1995. The use of fura-2 for estimating Ca buffers and Ca fluxes. Neuropharmacology 34:1423-42.
    • (1995) Neuropharmacology , vol.34 , pp. 1423-42
    • Neher, E.1
  • 107
    • 60549090787 scopus 로고    scopus 로고
    • The Psi(m) depolarization that accompanies mitochondrial Ca2+ uptake is greater in mutant SOD1 than in wild-type mouse motor terminals
    • Nguyen KT, Garcia-Chacon LE, Barrett JN, Barrett EF, David G. 2009. The Psi(m) depolarization that accompanies mitochondrial Ca2+ uptake is greater in mutant SOD1 than in wild-type mouse motor terminals. Proc Natl Acad Sci USA 106:2007-11.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 2007-11
    • Nguyen, K.T.1    Garcia-Chacon, L.E.2    Barrett, J.N.3    Barrett, E.F.4    David, G.5
  • 108
    • 79952754297 scopus 로고    scopus 로고
    • Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G(3)A transgenic ALS mice
    • Ozdinler PH, Benn S, Yamamoto TH, Guzel M, Brown RH Jr, Macklis JD. 2011. Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G(3)A transgenic ALS mice. J Neurosci 31:4166-77.
    • (2011) J Neurosci , vol.31 , pp. 4166-77
    • Ozdinler, P.H.1    Benn, S.2    Yamamoto, T.H.3    Guzel, M.4    Brown Jr., R.H.5    MacKlis, J.D.6
  • 109
    • 0033569575 scopus 로고    scopus 로고
    • Calcium dynamics and lowering in motoneurones of the mouse spinal cord
    • DOI 10.1111/j.1469-7793.1999.00485.x
    • Palecek J, Lips MB, Keller BU. 1999. Calcium dynamics and buffering in motoneurones of the mouse spinal cord. J Physiol 520 Pt 2:485-502. (Pubitemid 29511912)
    • (1999) Journal of Physiology , vol.520 , Issue.2 , pp. 485-502
    • Palecek, J.1    Lips, M.B.2    Keller, B.U.3
  • 110
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo CA, Xu Z, Borchelt DR, Price DL, Sisodia SS, Cleveland DW. 1995. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci USA 92:954-8.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 954-8
    • Pardo, C.A.1    Xu, Z.2    Borchelt, D.R.3    Price, D.L.4    Sisodia, S.S.5    Cleveland, D.W.6
  • 111
    • 24344508169 scopus 로고    scopus 로고
    • Synaptic release of serotonin induced by stimulation of the raphe nucleus promotes plateau potentials in spinal motoneurons of the adult turtle
    • DOI 10.1523/JNEUROSCI.1957-05.2005
    • Perrier JF, Delgado-Lezama R. 2005. Synaptic release of serotonin induced by stimulation of the raphe nucleus promotes plateau potentials in spinal motoneurons of the adult turtle. J Neurosci 25:7993-9. (Pubitemid 41254402)
    • (2005) Journal of Neuroscience , vol.25 , Issue.35 , pp. 7993-7999
    • Perrier, J.-F.1    Delgado-Lezama, R.2
  • 112
    • 79951704433 scopus 로고    scopus 로고
    • Neuroinflammation in amyotrophic lateral sclerosis: Role of glial activation in motor neuron disease
    • Philips T, Robberecht W. 2011. Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease. Lancet Neurol 10:253-63.
    • (2011) Lancet Neurol , vol.10 , pp. 253-63
    • Philips, T.1    Robberecht, W.2
  • 113
    • 58149527805 scopus 로고    scopus 로고
    • Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis
    • Pieri M, Carunchio I, Curcio L, Mercuri NB, Zona C. 2009. Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis. Exp Neurol 215:368-79.
    • (2009) Exp Neurol , vol.215 , pp. 368-79
    • Pieri, M.1    Carunchio, I.2    Curcio, L.3    Mercuri, N.B.4    Zona, C.5
  • 114
    • 77956319634 scopus 로고    scopus 로고
    • Calcium-dependent mitochondrial function and dysfunction in neurons
    • Pivovarova NB, Andrews SB. 2010. Calcium-dependent mitochondrial function and dysfunction in neurons. The FEBS journal 277:3622-36.
    • (2010) The FEBS Journal , vol.277 , pp. 3622-36
    • Pivovarova, N.B.1    Andrews, S.B.2
  • 117
    • 33344462702 scopus 로고    scopus 로고
    • Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
    • DOI 10.1038/nn1653
    • Pun S, Santos AF, Saxena S, Xu L, Caroni P. 2006. Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF. Nat Neurosci 9:408-19. (Pubitemid 43290971)
    • (2006) Nature Neuroscience , vol.9 , Issue.3 , pp. 408-419
    • Pun, S.1    Santos, A.F.2    Saxena, S.3    Xu, L.4    Caroni, P.5
  • 118
    • 79955421221 scopus 로고    scopus 로고
    • Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis
    • Quinlan KA, Schuster JE, Fu R, Siddique T, Heckman CJ. 2011. Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis. J Physiol 589:2245-60.
    • (2011) J Physiol , vol.589 , pp. 2245-60
    • Quinlan, K.A.1    Schuster, J.E.2    Fu, R.3    Siddique, T.4    Heckman, C.J.5
  • 119
    • 0037068836 scopus 로고    scopus 로고
    • Motoneuron death triggered by a specific pathway downstream of fas: Potentiation by ALS-linked SOD1 mutations
    • DOI 10.1016/S0896-6273(02)00905-4
    • Raoul C, Estevez AG, Nishimune H, Cleveland DW, deLapeyriere O, Henderson CE, Haase G, Pettmann B. 2002. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron 35:1067-83. (Pubitemid 35279535)
    • (2002) Neuron , vol.35 , Issue.6 , pp. 1067-1083
    • Raoul, C.1    Estevez, A.G.2    Nishimune, H.3    Cleveland, D.W.4    DeLapeyriere, O.5    Henderson, C.E.6    Haase, G.7    Pettmann, B.8
  • 121
    • 0028303110 scopus 로고
    • A comparative study of the calcium-binding proteins calbindin-D28K, calretinin, calmodulin and parvalbumin in the rat spinal cord
    • DOI 10.1016/0165-0173(94)90010-8
    • Ren K, Ruda MA. 1994. A comparative study of the calcium-binding proteins calbindin-D28K, calretinin, calmodulin and parvalbumin in the rat spinal cord. Brain Res Brain Res Rev 19:163-79. (Pubitemid 24150317)
    • (1994) Brain Research Reviews , vol.19 , Issue.2 , pp. 163-179
    • Ren, K.1    Ruda, M.A.2
  • 122
    • 33645843025 scopus 로고    scopus 로고
    • Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential
    • Rintoul GL, Bennett VJ, Papaconstandinou NA, Reynolds IJ. 2006. Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential. J Neurochem 97:800-6.
    • (2006) J Neurochem , vol.97 , pp. 800-6
    • Rintoul, G.L.1    Bennett, V.J.2    Papaconstandinou, N.A.3    Reynolds, I.J.4
  • 124
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • DOI 10.1038/nrm2199, PII NRM2199
    • Ron D, Walter P. 2007. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8:519-29. (Pubitemid 46985379)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.7 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 126
    • 0029847118 scopus 로고    scopus 로고
    • Excitotoxicity hypothesis
    • discussion S26
    • Rothstein JD. 1996. Excitotoxicity hypothesis. Neurology 47:S19-25. discussion S26.
    • (1996) Neurology , vol.47
    • Rothstein, J.D.1
  • 127
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein JD, Martin LJ, Kuncl RW. 1992. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 326:1464-8.
    • (1992) N Engl J Med , vol.326 , pp. 1464-8
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 129
    • 0035947131 scopus 로고    scopus 로고
    • EAAT1 and EAAT2 immunoreactivity in transgenic mice with a G93A mutant SODI gene
    • Sasaki S, Warita H, Abe K, Komori T, Iwata M. 2001. EAAT1 and EAAT2 immunoreactivity in transgenic mice with a G93A mutant SOD1 gene. Neuroreport 12:1359-62. (Pubitemid 32476129)
    • (2001) NeuroReport , vol.12 , Issue.7 , pp. 1359-1362
    • Sasaki, S.1    Warita, H.2    Abe, K.3    Komori, T.4    Iwata, M.5
  • 130
    • 67349164383 scopus 로고    scopus 로고
    • A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
    • Saxena S, Cabuy E, Caroni P. 2009. A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice. Nat Neurosci 12:627-36.
    • (2009) Nat Neurosci , vol.12 , pp. 627-36
    • Saxena, S.1    Cabuy, E.2    Caroni, P.3
  • 131
    • 79960167259 scopus 로고    scopus 로고
    • Selective neuronal vulnerability in neurodegenerative diseases: From stressor thresholds to degeneration
    • Saxena S, Caroni P. 2011. Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration. Neuron 71:35-48.
    • (2011) Neuron , vol.71 , pp. 35-48
    • Saxena, S.1    Caroni, P.2
  • 132
    • 0030957325 scopus 로고    scopus 로고
    • Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons
    • Schwarzschild MA, Cole RL, Hyman SE. 1997. Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons. J Neurosci 17:3455-66. (Pubitemid 27200575)
    • (1997) Journal of Neuroscience , vol.17 , Issue.10 , pp. 3455-3466
    • Schwarzschild, M.A.1    Cole, R.L.2    Hyman, S.E.3
  • 133
    • 33845680588 scopus 로고    scopus 로고
    • Electrical activity in early neuronal development
    • DOI 10.1038/nature05300, PII NATURE05300
    • Spitzer NC. 2006. Electrical activity in early neuronal development. Nature 444:707-12. (Pubitemid 44949593)
    • (2006) Nature , vol.444 , Issue.7120 , pp. 707-712
    • Spitzer, N.C.1
  • 135
    • 33745905621 scopus 로고    scopus 로고
    • Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: Implications for AMPA receptor-mediated excitotoxicity in ALS
    • DOI 10.1111/j.1471-4159.2006.03903.x
    • Sun H, Kawahara Y, Ito K, Kanazawa I, Kwak S. 2006. Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptormediated excitotoxicity in ALS. J Neurochem 98:782-91. (Pubitemid 44051279)
    • (2006) Journal of Neurochemistry , vol.98 , Issue.3 , pp. 782-791
    • Sun, H.1    Kawahara, Y.2    Ito, K.3    Kanazawa, I.4    Kwak, S.5
  • 136
    • 80052936462 scopus 로고    scopus 로고
    • Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
    • Swarup V, Phaneuf D, Bareil C, Robertson J, Rouleau GA, Kriz J, Julien JP. 2011. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain 134(Pt 9):2610-26.
    • (2011) Brain , vol.134 , Issue.PART 9 , pp. 2610-26
    • Swarup, V.1    Phaneuf, D.2    Bareil, C.3    Robertson, J.4    Rouleau, G.A.5    Kriz, J.6    Julien, J.P.7
  • 138
    • 0017698204 scopus 로고
    • The numbers of limb motor neurons in the human lumbosacral cord throughout life
    • DOI 10.1016/0022-510X(77)90069-7
    • Tomlinson BE, Irving D. 1977. The numbers of limb motor neurons in the human lumbosacral cord throughout life. J Neurol Sci 34:213-9. (Pubitemid 8188068)
    • (1977) Journal of the Neurological Sciences , vol.34 , Issue.2 , pp. 213-219
    • Tomlinson, B.E.1    Irving, D.2
  • 140
    • 0038383029 scopus 로고    scopus 로고
    • Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression
    • DOI 10.1016/S1044-7431(03)00022-8
    • Tortarolo M, Veglianese P, Calvaresi N, Botturi A, Rossi C, Giorgini A, Migheli A, Bendotti C. 2003. Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression. Mol Cell Neurosci 23:180-92. (Pubitemid 36703155)
    • (2003) Molecular and Cellular Neuroscience , vol.23 , Issue.2 , pp. 180-192
    • Tortarolo, M.1    Veglianese, P.2    Calvaresi, N.3    Botturi, A.4    Rossi, C.5    Giorgini, A.6    Migheli, A.7    Bendotti, C.8
  • 142
    • 0042827316 scopus 로고    scopus 로고
    • Neuromuscular accumulation of mutant superoxide dismutase 1 aggregates in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • DOI 10.1016/S0304-3940(03)00893-0
    • Turner BJ, Lopes EC, Cheema SS. 2003. Neuromuscular accumulation of mutant superoxide dismutase 1 aggregates in a transgenic mouse model of familial amyotrophic lateral sclerosis. Neurosci Lett 350:132-6. (Pubitemid 37101429)
    • (2003) Neuroscience Letters , vol.350 , Issue.2 , pp. 132-136
    • Turner, B.J.1    Lopes, E.C.2    Cheema, S.S.3
  • 143
    • 0033787252 scopus 로고    scopus 로고
    • Riluzole inhibits the persistent sodium current in mammalian CNS neurons
    • Urbani A, Belluzzi O. 2000. Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur J Neurosci 12:3567-74.
    • (2000) Eur J Neurosci , vol.12 , pp. 3567-74
    • Urbani, A.1    Belluzzi, O.2
  • 145
    • 79952233317 scopus 로고    scopus 로고
    • Genetic rodent models of amyotrophic lateral sclerosis
    • Van Den Bosch L. 2011. Genetic rodent models of amyotrophic lateral sclerosis. J Biomed Biotechnol 2011:348765.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 348765
    • Van Den Bosch, L.1
  • 146
    • 58149173426 scopus 로고    scopus 로고
    • Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis
    • van Zundert B, Peuscher MH, Hynynen M, Chen A, Neve RL, Brown RH Jr, Constantine-Paton M, Bellingham MC. 2008. Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis. J Neurosci 28:10864-10874.
    • (2008) J Neurosci , vol.28 , pp. 10864-10874
    • Van Zundert, B.1    Peuscher, M.H.2    Hynynen, M.3    Chen, A.4    Neve, R.L.5    Brown Jr., R.H.6    Constantine-Paton, M.7    Bellingham, M.C.8
  • 147
    • 0034212794 scopus 로고    scopus 로고
    • Calcium dynamics and buffering in oculomotor neurones from mouse that are particularly resistant during amyotrophic lateral sclerosis (ALS)-related
    • Vanselow BK, Keller BU. 2000. Calcium dynamics and buffering in oculomotor neurones from mouse that are particularly resistant during amyotrophic lateral sclerosis (ALS)-related motoneurone disease. J Physiol 525(Pt 2):433-445. (Pubitemid 30398372)
    • (2000) Journal of Physiology , vol.525 , Issue.2 , pp. 433-445
    • Vanselow, B.K.1    Keller, B.U.2
  • 148
    • 0034668714 scopus 로고    scopus 로고
    • Perinatal development of lumbar motoneurons and their inputs in the rat
    • DOI 10.1016/S0361-9230(00)00397-X, PII S036192300000397X
    • Vinay L, Brocard F, Pflieger JF, Simeoni-Alias J, Clarac F. 2000. Perinatal development of lumbar motoneurons and their inputs in the rat. Brain Res Bull 53:635-47. (Pubitemid 32114316)
    • (2000) Brain Research Bulletin , vol.53 , Issue.5 , pp. 635-647
    • Vinay, L.1    Brocard, F.2    Pflieger, J.-F.3    Simeoni-Alias, J.4    Clarac, F.5
  • 149
    • 39749172372 scopus 로고    scopus 로고
    • Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor
    • DOI 10.1038/nn2044, PII NN2044
    • Vizard TN, O'Keeffe GW, Gutierrez H, Kos CH, Riccardi D, Davies AM. 2008. Regulation of axonal and dendritic growth by the extracellular calcium-sensing receptor. Nat Neurosci 11:285-91. (Pubitemid 351311792)
    • (2008) Nature Neuroscience , vol.11 , Issue.3 , pp. 285-291
    • Vizard, T.N.1    O'Keeffe, G.W.2    Gutierrez, H.3    Kos, C.H.4    Riccardi, D.5    Davies, A.M.6
  • 150
    • 53249134366 scopus 로고    scopus 로고
    • Low Ca2+ buffering in hypoglossal motoneurons of mutant SOD1 (G93A) mice
    • von Lewinski F, Fuchs J, Vanselow BK, Keller BU. 2008. Low Ca2+ buffering in hypoglossal motoneurons of mutant SOD1 (G93A) mice. Neurosci Lett 445:224-8.
    • (2008) Neurosci Lett , vol.445 , pp. 224-8
    • Von Lewinski, F.1    Fuchs, J.2    Vanselow, B.K.3    Keller, B.U.4
  • 151
    • 18144399681 scopus 로고    scopus 로고
    • 2+ buffering in hypoglossal motoneurons from mouse
    • DOI 10.1016/j.neulet.2005.01.010
    • von Lewinski F, Keller BU. 2005. Mitochondrial Ca2+ buffering in hypoglossal motoneurons from mouse. Neurosci Lett 380:203-8. (Pubitemid 40616080)
    • (2005) Neuroscience Letters , vol.380 , Issue.3 , pp. 203-208
    • Von Lewinski, F.1    Keller, B.U.2
  • 152
    • 76549107634 scopus 로고    scopus 로고
    • Upregulation of persistent sodium conductances in familial ALS
    • Vucic S, Kiernan MC. 2010. Upregulation of persistent sodium conductances in familial ALS. J Neurol Neurosurg Psychiatry 81:222-7.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 222-7
    • Vucic, S.1    Kiernan, M.C.2
  • 153
    • 44949243975 scopus 로고    scopus 로고
    • Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis
    • DOI 10.1093/brain/awn071
    • Vucic S, Nicholson GA, Kiernan MC. 2008. Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis. Brain 131:1540-50. (Pubitemid 351806458)
    • (2008) Brain , vol.131 , Issue.6 , pp. 1540-1550
    • Vucic, S.1    Nicholson, G.A.2    Kiernan, M.C.3
  • 155
    • 67649486844 scopus 로고    scopus 로고
    • The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis
    • Wang L, Sharma K, Grisotti G, Roos RP. 2009. The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis. Neurobiol Dis 35:234-40.
    • (2009) Neurobiol Dis , vol.35 , pp. 234-40
    • Wang, L.1    Sharma, K.2    Grisotti, G.3    Roos, R.P.4
  • 156
    • 1642462299 scopus 로고    scopus 로고
    • Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes)
    • Wang SJ, Wang KY, Wang WC. 2004. Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes). Neuroscience 125:191-201.
    • (2004) Neuroscience , vol.125 , pp. 191-201
    • Wang, S.J.1    Wang, K.Y.2    Wang, W.C.3
  • 157
    • 0033585832 scopus 로고    scopus 로고
    • Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene
    • DOI 10.1016/S0006-8993(98)01351-1, PII S0006899398013511
    • Warita H, Itoyama Y, Abe K. 1999. Selective impairment of fast anterograde axonal transport in the peripheral nerves of asymptomatic transgenic mice with a G93A mutant SOD1 gene. Brain Res 819:120-31. (Pubitemid 29225463)
    • (1999) Brain Research , vol.819 , Issue.1-2 , pp. 120-131
    • Warita, H.1    Itoyama, Y.2    Abe, K.3
  • 158
    • 0036715493 scopus 로고    scopus 로고
    • Tardive decrease of astrocytic glutamate transporter protein in transgenic mice with ALS-linked mutant SOD1
    • DOI 10.1179/016164102101200384
    • Warita H, Manabe Y, Murakami T, Shiote M, Shiro Y, Hayashi T, Nagano I, Shoji M, Abe K. 2002. Tardive decrease of astrocytic glutamate transporter protein in transgenic mice with ALS-linked mutant SOD1. Neurological Res 24:577-81. (Pubitemid 35024486)
    • (2002) Neurological Research , vol.24 , Issue.6 , pp. 577-581
    • Warita, H.1    Manabe, Y.2    Murakami, T.3    Shiote, M.4    Shiro, Y.5    Hayashi, T.6    Nagano, I.7    Shoji, M.8    Abe, K.9
  • 160
    • 0033366384 scopus 로고    scopus 로고
    • Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
    • DOI 10.1038/4553
    • Williamson TL, Cleveland DW. 1999. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat Neurosci 2:50-6. (Pubitemid 30488940)
    • (1999) Nature Neuroscience , vol.2 , Issue.1 , pp. 50-56
    • Williamson, T.L.1    Cleveland, D.W.2
  • 161
    • 0036303818 scopus 로고    scopus 로고
    • Genetically engineered mouse models of neurodegenerative diseases
    • DOI 10.1038/nn0702-633
    • Wong PC, Cai H, Borchelt DR, Price DL. 2002. Genetically engineered mouse models of neurodegenerative diseases. Nat Neurosci 5:633-9. (Pubitemid 34742978)
    • (2002) Nature Neuroscience , vol.5 , Issue.7 , pp. 633-639
    • Wong, P.C.1    Cai, H.2    Borchelt, D.R.3    Price, D.L.4
  • 162
  • 163
    • 0035882358 scopus 로고    scopus 로고
    • 1 L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines
    • Xu W, Lipscombe D. 2001. Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. J Neurosci 21:5944-51. (Pubitemid 32737727)
    • (2001) Journal of Neuroscience , vol.21 , Issue.16 , pp. 5944-5951
    • Xu, W.1    Lipscombe, D.2
  • 165
    • 77956404377 scopus 로고    scopus 로고
    • Eaten alive: A history of macroautophagy
    • Yang Z, Klionsky DJ. 2010. Eaten alive: a history of macroautophagy. Nat Cell Biol 12:814-22.
    • (2010) Nat Cell Biol , vol.12 , pp. 814-22
    • Yang, Z.1    Klionsky, D.J.2
  • 166
    • 9444226972 scopus 로고    scopus 로고
    • Control of mitochondrial motility and distribution by the calcium signal: A homeostatic circuit
    • DOI 10.1083/jcb.200406038
    • Yi M, Weaver D, Hajnoczky G. 2004. Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit. J Cell Biol 167:661-72. (Pubitemid 39565147)
    • (2004) Journal of Cell Biology , vol.167 , Issue.4 , pp. 661-672
    • Yi, M.1    Weaver, D.2    Hajnoczky, G.3
  • 167
    • 0030817291 scopus 로고    scopus 로고
    • Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
    • DOI 10.1083/jcb.139.5.1307
    • Zhang B, Tu P, Abtahian F, Trojanowski JQ, Lee VM. 1997. Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation. J Cell Biol 139:1307-15. (Pubitemid 27523216)
    • (1997) Journal of Cell Biology , vol.139 , Issue.5 , pp. 1307-1315
    • Zhang, B.1    Tu, P.-H.2    Abtahian, F.3    Trojanowski, J.Q.4    Lee, V.M.-Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.