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Volumn 99, Issue 3, 2006, Pages 900-912

Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis

Author keywords

Amyotrophic lateral sclerosis; Glia; K+ buffering; KCNJ10; Neurone glia interaction; Superoxide dismutase 1 transgenic mice

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL; MUTANT PROTEIN; POTASSIUM ION; SUPEROXIDE DISMUTASE;

EID: 33750057964     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04131.x     Document Type: Article
Times cited : (86)

References (56)
  • 4
    • 0037320806 scopus 로고    scopus 로고
    • Modulation of glutamatergic transmission by bergmann glial cells in rat cerebellum in situ
    • Bordey A. and Sontheimer H. (2003) Modulation of glutamatergic transmission by bergmann glial cells in rat cerebellum in situ. J. Neurophysiol. 89, 979-988.
    • (2003) J. Neurophysiol. , vol.89 , pp. 979-988
    • Bordey, A.1    Sontheimer, H.2
  • 5
    • 0031051485 scopus 로고    scopus 로고
    • ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions
    • Bruijn L. I., Becher M. W., Lee M. K. et al. (1997) ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron 18, 327-338.
    • (1997) Neuron , vol.18 , pp. 327-338
    • Bruijn, L.I.1    Becher, M.W.2    Lee, M.K.3
  • 7
    • 0141642203 scopus 로고    scopus 로고
    • Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
    • Clement A. M., Nguyen M. D., Roberts E. A. et al. (2003) Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 302, 113-117.
    • (2003) Science , vol.302 , pp. 113-117
    • Clement, A.M.1    Nguyen, M.D.2    Roberts, E.A.3
  • 9
    • 10744227341 scopus 로고    scopus 로고
    • Targeted inactivation of dystrophin gene product Dp71: Phenotypic impact in mouse retina
    • Dalloz C., Sarig R., Fort P. et al. (2003) Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina. Hum. Mol. Genet. 12, 1543-1554.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1543-1554
    • Dalloz, C.1    Sarig, R.2    Fort, P.3
  • 10
    • 0027426169 scopus 로고
    • Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase
    • Deng H. X., Hentati A., Tainer J. A. et al. (1993) Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase. Science 261, 1047-1051.
    • (1993) Science , vol.261 , pp. 1047-1051
    • Deng, H.X.1    Hentati, A.2    Tainer, J.A.3
  • 11
    • 0032427186 scopus 로고    scopus 로고
    • +-ATPase alpha and beta subunit isoforms in the motor neurons of the rat spinal cord
    • +-ATPase alpha and beta subunit isoforms in the motor neurons of the rat spinal cord. Membr. Cell Biol. 12, 355-361.
    • (1998) Membr. Cell Biol. , vol.12 , pp. 355-361
    • Dolapchieva, S.D.1
  • 12
    • 0027714989 scopus 로고
    • Evaluation of the spinal cord neuron x neuroblastoma hybrid cell line NSC-34 as a model for neurotoxicity testing
    • Durham H. D., Dahrouge S. and Cashman N. R. (1993) Evaluation of the spinal cord neuron x neuroblastoma hybrid cell line NSC-34 as a model for neurotoxicity testing. Neurotoxicology 14, 387-395.
    • (1993) Neurotoxicology , vol.14 , pp. 387-395
    • Durham, H.D.1    Dahrouge, S.2    Cashman, N.R.3
  • 13
    • 0037221596 scopus 로고    scopus 로고
    • Global loss of Na,K-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis
    • Ellis D. Z., Rabe J. and Sweadner K. J. (2003) Global loss of Na,K-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurosci. 23, 43-51.
    • (2003) J. Neurosci. , vol.23 , pp. 43-51
    • Ellis, D.Z.1    Rabe, J.2    Sweadner, K.J.3
  • 14
    • 0032489007 scopus 로고    scopus 로고
    • Effects of barium on stimulus induced changes in extracellular potassium concentration in area CA1 of hippocampal slices from normal and pilocarpine-treated epileptic rats
    • Gabriel S., Eilers A., Kivi A., Kovacs R., Schulze K., Lehmann T. N. and Heinemann U. (1998) Effects of barium on stimulus induced changes in extracellular potassium concentration in area CA1 of hippocampal slices from normal and pilocarpine-treated epileptic rats. Neurosci. Lett. 242, 9-12.
    • (1998) Neurosci. Lett. , vol.242 , pp. 9-12
    • Gabriel, S.1    Eilers, A.2    Kivi, A.3    Kovacs, R.4    Schulze, K.5    Lehmann, T.N.6    Heinemann, U.7
  • 15
    • 0034651102 scopus 로고    scopus 로고
    • Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
    • Gong Y. H., Parsadanian A. S., Andreeva A., Snider W. D. and Elliott J. L. (2000) Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J. Neurosci. 20, 660-665.
    • (2000) J. Neurosci. , vol.20 , pp. 660-665
    • Gong, Y.H.1    Parsadanian, A.S.2    Andreeva, A.3    Snider, W.D.4    Elliott, J.L.5
  • 16
    • 3943068322 scopus 로고    scopus 로고
    • Laminin-induced aggregation of the inwardly rectifying potassium channel, Kir4.1, and the water-permeable channel, AQP4, via a dystroglycan-containing complex in astrocytes
    • Guadagno E. and Moukhles H. (2004) Laminin-induced aggregation of the inwardly rectifying potassium channel, Kir4.1, and the water-permeable channel, AQP4, via a dystroglycan-containing complex in astrocytes. Glia 47, 138-149.
    • (2004) Glia , vol.47 , pp. 138-149
    • Guadagno, E.1    Moukhles, H.2
  • 17
    • 0030927253 scopus 로고    scopus 로고
    • Transgenic animal models of familial amyotrophic lateral sclerosis
    • Gurney M. E. (1997) Transgenic animal models of familial amyotrophic lateral sclerosis. J. Neurol. 244, S15-S20.
    • (1997) J. Neurol. , vol.244
    • Gurney, M.E.1
  • 18
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
    • Gurney M. E., Pu H., Chiu A. Y. et al. (1994) Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264, 1772-1775.
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1    Pu, H.2    Chiu, A.Y.3
  • 19
    • 0029991177 scopus 로고    scopus 로고
    • Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase
    • Gurney M. E., Cutting F. B., Zhai P., Andrus P. K. and Hall E. D. (1996) Pathogenic mechanisms in familial amyotrophic lateral sclerosis due to mutation of Cu, Zn superoxide dismutase. Pathol. Biol. (Paris) 44, 51-56.
    • (1996) Pathol. Biol. (Paris) , vol.44 , pp. 51-56
    • Gurney, M.E.1    Cutting, F.B.2    Zhai, P.3    Andrus, P.K.4    Hall, E.D.5
  • 21
    • 0032125587 scopus 로고    scopus 로고
    • Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
    • Hall E. D., Oostveen J. A. and Gurney M. E. (1998) Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 23, 249-256.
    • (1998) Glia , vol.23 , pp. 249-256
    • Hall, E.D.1    Oostveen, J.A.2    Gurney, M.E.3
  • 24
    • 0037022339 scopus 로고    scopus 로고
    • Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
    • Howland D. S., Liu J., She Y. et al. (2002) Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc. Natl Acad. Sci. USA 99, 1604-1609.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 1604-1609
    • Howland, D.S.1    Liu, J.2    She, Y.3
  • 25
    • 0346120435 scopus 로고    scopus 로고
    • Seizures preferentially stimulate proliferation of radial glia-like astrocytes in the adult dentate gyrus: Functional and immunocytochemical analysis
    • Huttmann K., Sadgrove M., Wallraff A., Hinterkeuser S., Kirchhoff F., Steinhauser C. and Gray W. P. (2003) Seizures preferentially stimulate proliferation of radial glia-like astrocytes in the adult dentate gyrus: functional and immunocytochemical analysis. Eur. J. Neurosci. 18, 2769-2778.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2769-2778
    • Huttmann, K.1    Sadgrove, M.2    Wallraff, A.3    Hinterkeuser, S.4    Kirchhoff, F.5    Steinhauser, C.6    Gray, W.P.7
  • 26
    • 0037126962 scopus 로고    scopus 로고
    • Effects of barium, furosemide, ouabaine and 4,4′- diisothiocyanatostilbene-2,2′-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy
    • Jauch R., Windmuller O., Lehmann T. N., Heinemann U. and Gabriel S. (2002) Effects of barium, furosemide, ouabaine and 4,4′- diisothiocyanatostilbene-2,2′-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy. Brain Res. 925, 18-27.
    • (2002) Brain Res. , vol.925 , pp. 18-27
    • Jauch, R.1    Windmuller, O.2    Lehmann, T.N.3    Heinemann, U.4    Gabriel, S.5
  • 27
    • 3042601160 scopus 로고    scopus 로고
    • Kir4.1 expression by astrocytes and oligodendrocytes in CNS white matter: A developmental study in the rat optic nerve
    • Kalsi A. S., Greenwood K., Wilkin G. and Butt A. M. (2004) Kir4.1 expression by astrocytes and oligodendrocytes in CNS white matter: a developmental study in the rat optic nerve. J. Anat. 204, 475-485.
    • (2004) J. Anat. , vol.204 , pp. 475-485
    • Kalsi, A.S.1    Greenwood, K.2    Wilkin, G.3    Butt, A.M.4
  • 28
    • 0034255132 scopus 로고    scopus 로고
    • Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: Phenotypic impact in retina
    • Kofuji P., Ceelen P., Zahs K. R., Surbeck L. W., Lester H. A. and Newman E. A. (2000) Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina. J. Neurosci. 20, 5733-5740.
    • (2000) J. Neurosci. , vol.20 , pp. 5733-5740
    • Kofuji, P.1    Ceelen, P.2    Zahs, K.R.3    Surbeck, L.W.4    Lester, H.A.5    Newman, E.A.6
  • 30
    • 0037096354 scopus 로고    scopus 로고
    • Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
    • Lino M. M., Schneider C. and Caroni P. (2002) Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J. Neurosci. 22, 4825-4832.
    • (2002) J. Neurosci. , vol.22 , pp. 4825-4832
    • Lino, M.M.1    Schneider, C.2    Caroni, P.3
  • 31
    • 9344226163 scopus 로고    scopus 로고
    • New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice
    • Manley G. T., Binder D. K., Papadopoulos M. C. and Verkman A. S. (2004) New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience 129, 983-991.
    • (2004) Neuroscience , vol.129 , pp. 983-991
    • Manley, G.T.1    Binder, D.K.2    Papadopoulos, M.C.3    Verkman, A.S.4
  • 32
    • 0035575761 scopus 로고    scopus 로고
    • Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: Associated mutations develop motor neuron disease
    • Nagai M., Aoki M., Miyoshi I., Kato M., Pasinelli P., Kasai N., Brown R. H. Jr and Itoyama Y. (2001) Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease. J. Neurosci. 21, 9246-9254.
    • (2001) J. Neurosci. , vol.21 , pp. 9246-9254
    • Nagai, M.1    Aoki, M.2    Miyoshi, I.3    Kato, M.4    Pasinelli, P.5    Kasai, N.6    Brown Jr., R.H.7    Itoyama, Y.8
  • 34
    • 0035425966 scopus 로고    scopus 로고
    • Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination
    • Neusch C., Rozengurt N., Jacobs R. E., Lester H. A. and Kofuji P. (2001) Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination. J. Neurosci. 21, 5429-5438.
    • (2001) J. Neurosci. , vol.21 , pp. 5429-5438
    • Neusch, C.1    Rozengurt, N.2    Jacobs, R.E.3    Lester, H.A.4    Kofuji, P.5
  • 37
    • 0023395152 scopus 로고
    • Distribution of potassium conductance in mammalian Muller (glial) cells: A comparative study
    • Newman E. A. (1987) Distribution of potassium conductance in mammalian Muller (glial) cells: a comparative study. J. Neurosci. 7, 2423-2432.
    • (1987) J. Neurosci. , vol.7 , pp. 2423-2432
    • Newman, E.A.1
  • 38
    • 0027184270 scopus 로고
    • Inward-rectifying potassium channels in retinal glial (Muller) cells
    • Newman E. A. (1993) Inward-rectifying potassium channels in retinal glial (Muller) cells. J. Neurosci. 13, 3333-3345.
    • (1993) J. Neurosci. , vol.13 , pp. 3333-3345
    • Newman, E.A.1
  • 39
    • 0030201340 scopus 로고    scopus 로고
    • The Muller cell: A functional element of the retina
    • Newman E. and Reichenbach A. (1996) The Muller cell: a functional element of the retina. Trends Neurosci. 19, 307-312.
    • (1996) Trends Neurosci. , vol.19 , pp. 307-312
    • Newman, E.1    Reichenbach, A.2
  • 41
    • 0035132767 scopus 로고    scopus 로고
    • GFAP promoter-controlled EGFP-expressing transgenic mice: A tool to visualize astrocytes and astrogliosis in living brain tissue
    • Nolte C., Matyash M., Pivneva T., Schipke C. G., Ohlemeyer C., Hanisch U. K., Kirchhoff F. and Kettenmann H. (2001) GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue. Glia 33, 72-86.
    • (2001) Glia , vol.33 , pp. 72-86
    • Nolte, C.1    Matyash, M.2    Pivneva, T.3    Schipke, C.G.4    Ohlemeyer, C.5    Hanisch, U.K.6    Kirchhoff, F.7    Kettenmann, H.8
  • 42
    • 33645392998 scopus 로고    scopus 로고
    • Functional expression of K(ir) 4.1 channels in spinal cord astrocytes
    • Olsen M. L., Higashimori H., Campbell S. L., HablitZ. J. J. and Sontheimer H. (2005) Functional expression of K(ir) 4.1 channels in spinal cord astrocytes. Glia 53, 516-528.
    • (2005) Glia , vol.53 , pp. 516-528
    • Olsen, M.L.1    Higashimori, H.2    Campbell, S.L.3    Hablitz, J.J.4    Sontheimer, H.5
  • 45
    • 0035873076 scopus 로고    scopus 로고
    • Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
    • Pramatarova A., Laganiere J., Roussel J., Brisebois K. and Rouleau G. A. (2001) Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J. Neurosci. 21, 3369-3374.
    • (2001) J. Neurosci. , vol.21 , pp. 3369-3374
    • Pramatarova, A.1    Laganiere, J.2    Roussel, J.3    Brisebois, K.4    Rouleau, G.A.5
  • 46
    • 0032578454 scopus 로고    scopus 로고
    • Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
    • Rash J. E., Yasumura T., Hudson C. S., Agre P. and Nielsen S. (1998) Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. Proc. Natl Acad. Sci. USA 95, 11 981-11 986.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 11981-11986
    • Rash, J.E.1    Yasumura, T.2    Hudson, C.S.3    Agre, P.4    Nielsen, S.5
  • 47
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen D. R., Siddique T., Patterson D. et al. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3
  • 49
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein J. D., Martin L. J. and Kuncl R. W. (1992) Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 326, 1464-1468.
    • (1992) N. Engl. J. Med. , vol.326 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 50
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein J. D., Van Kammen M., Levey A. I., Martin L. J. and Kuncl R. W. (1995) Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol. 38, 73-84.
    • (1995) Ann. Neurol. , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 51
    • 0346780560 scopus 로고    scopus 로고
    • + siphoning in brain contusion, bacterial meningitis, and brain tumours: Immunohistochemical case review
    • + siphoning in brain contusion, bacterial meningitis, and brain tumours: immunohistochemical case review. J. Clin. Pathol. 56, 972-975.
    • (2003) J. Clin. Pathol. , vol.56 , pp. 972-975
    • Saadoun, S.1    Papadopoulos, M.C.2    Krishna, S.3
  • 52
    • 0033811922 scopus 로고    scopus 로고
    • Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy
    • Schroder W., Hinterkeuser S., Seifert G., Schramm J., Jabs R., Wilkin G. P. and Steinhauser C. (2000) Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy. Epilepsia 41, S181-S184.
    • (2000) Epilepsia , vol.41
    • Schroder, W.1    Hinterkeuser, S.2    Seifert, G.3    Schramm, J.4    Jabs, R.5    Wilkin, G.P.6    Steinhauser, C.7
  • 53
    • 0033366461 scopus 로고    scopus 로고
    • SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter
    • Trotti D., Rolfs A., Danbolt N. C., Brown R. H. Jr and Hediger M. A. (1999) SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter. Nat. Neurosci. 2, 427-433.
    • (1999) Nat. Neurosci. , vol.2 , pp. 427-433
    • Trotti, D.1    Rolfs, A.2    Danbolt, N.C.3    Brown Jr., R.H.4    Hediger, M.A.5
  • 54
    • 9444252293 scopus 로고    scopus 로고
    • Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS)
    • Vanoni C., Massari S., Losa M., Carrega P., Perego C., Conforti L. and Pietrini G. (2004) Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS). J. Cell Sci. 117, 5417-5426.
    • (2004) J. Cell Sci. , vol.117 , pp. 5417-5426
    • Vanoni, C.1    Massari, S.2    Losa, M.3    Carrega, P.4    Perego, C.5    Conforti, L.6    Pietrini, G.7
  • 55
    • 23844465582 scopus 로고    scopus 로고
    • Distribution of Aquaporin 4 in rodent spinal cord: Relationship with astrocyte markers and chondroitin sulfate proteoglycans
    • Vitellaro-Zuccarello L., Mazzetti S., Bosisio P., Monti C. and De Biasi S. (2005) Distribution of Aquaporin 4 in rodent spinal cord: Relationship with astrocyte markers and chondroitin sulfate proteoglycans. Glia 51, 148-159.
    • (2005) Glia , vol.51 , pp. 148-159
    • Vitellaro-Zuccarello, L.1    Mazzetti, S.2    Bosisio, P.3    Monti, C.4    De Biasi, S.5
  • 56
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong P. C., Pardo C. A., Borchelt D. R., Lee M. K., Copeland N. G., Jenkins N. A., Sisodia S. S., Cleveland D. W. and Price D. L. (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14, 1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9


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