메뉴 건너뛰기




Volumn 589, Issue 9, 2011, Pages 2245-2260

Altered postnatal maturation of electrical properties in spinal motoneurons in a mouse model of amyotrophic lateral sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

EID: 79955421221     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.200659     Document Type: Article
Times cited : (102)

References (80)
  • 1
    • 0036025041 scopus 로고    scopus 로고
    • Mechanisms causing plateau potentials in spinal motoneurones
    • Alaburda A, Perrier JF & Hounsgaard J (2002). Mechanisms causing plateau potentials in spinal motoneurones. Adv Exp Med Biol 508, 219-226.
    • (2002) Adv Exp Med Biol , vol.508 , pp. 219-226
    • Alaburda, A.1    Perrier, J.F.2    Hounsgaard, J.3
  • 2
    • 58149169031 scopus 로고    scopus 로고
    • Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice
    • Amendola J & Durand J (2008). Morphological differences between wild-type and transgenic superoxide dismutase 1 lumbar motoneurons in postnatal mice. J Comp Neurol 511, 329-341.
    • (2008) J Comp Neurol , vol.511 , pp. 329-341
    • Amendola, J.1    Durand, J.2
  • 3
    • 0034698248 scopus 로고    scopus 로고
    • Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes
    • Azbill RD, Mu X & Springer JE (2000). Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes. Brain Res 871, 175-180.
    • (2000) Brain Res , vol.871 , pp. 175-180
    • Azbill, R.D.1    Mu, X.2    Springer, J.E.3
  • 4
    • 33646885467 scopus 로고    scopus 로고
    • Mitochondrial involvement in amyotrophic lateral sclerosis: trigger or target?
    • amp; ().
    • Bacman SR, Bradley WG & Moraes CT (2006). Mitochondrial involvement in amyotrophic lateral sclerosis: trigger or target? Mol Neurobiol 33, 113-131.
    • (2006) Mol Neurobiol , vol.33 , pp. 113-131
    • Bacman, S.R.1    Bradley, W.G.2    Moraes, C.T.3
  • 6
    • 0034786606 scopus 로고    scopus 로고
    • Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro
    • Bennett DJ, Li Y & Siu M (2001). Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro. J Neurophysiol 86, 1955-1971.
    • (2001) J Neurophysiol , vol.86 , pp. 1955-1971
    • Bennett, D.J.1    Li, Y.2    Siu, M.3
  • 7
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group
    • Bensimon G, Lacomblez L & Meininger V (1994). A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group. N Engl J Med 330, 585-591.
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 8
    • 72849106974 scopus 로고    scopus 로고
    • Mechanisms underlying spontaneous patterned activity in developing neural circuits
    • Blankenship AG & Feller MB (2010). Mechanisms underlying spontaneous patterned activity in developing neural circuits. Nat Rev Neurosci 11, 18-29.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 18-29
    • Blankenship, A.G.1    Feller, M.B.2
  • 10
    • 0037444623 scopus 로고    scopus 로고
    • Functional specialization of the axon initial segment by isoform-specific sodium channel targeting
    • Boiko T, Van Wart A, Caldwell JH, Levinson SR, Trimmer JS & Matthews G (2003). Functional specialization of the axon initial segment by isoform-specific sodium channel targeting. J Neurosci 23, 2306-2313.
    • (2003) J Neurosci , vol.23 , pp. 2306-2313
    • Boiko, T.1    Van Wart, A.2    Caldwell, J.H.3    Levinson, S.R.4    Trimmer, J.S.5    Matthews, G.6
  • 11
    • 33847017739 scopus 로고    scopus 로고
    • Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis
    • Bories C, Amendola J, Lamotte d'Incamps B & Durand J (2007). Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis. Eur J Neurosci 25, 451-459.
    • (2007) Eur J Neurosci , vol.25 , pp. 451-459
    • Bories, C.1    Amendola, J.2    Lamotte d'Incamps, B.3    Durand, J.4
  • 13
    • 23844551823 scopus 로고    scopus 로고
    • Changes during the postnatal development in physiological and anatomical characteristics of rat motoneurons studied in vitro
    • Carrascal L, Nieto-Gonzalez JL, Cameron WE, Torres B & Nunez-Abades PA (2005). Changes during the postnatal development in physiological and anatomical characteristics of rat motoneurons studied in vitro. Brain Res Brain Res Rev 49, 377-387.
    • (2005) Brain Res Brain Res Rev , vol.49 , pp. 377-387
    • Carrascal, L.1    Nieto-Gonzalez, J.L.2    Cameron, W.E.3    Torres, B.4    Nunez-Abades, P.A.5
  • 14
    • 77957781372 scopus 로고    scopus 로고
    • Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture
    • Carunchio I, Curcio L, Pieri M, Pica F, Caioli S, Viscomi MT, Molinari M, Canu N, Bernardi G & Zona C (2010). Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture. Exp Neurol 226, 218-230.
    • (2010) Exp Neurol , vol.226 , pp. 218-230
    • Carunchio, I.1    Curcio, L.2    Pieri, M.3    Pica, F.4    Caioli, S.5    Viscomi, M.T.6    Molinari, M.7    Canu, N.8    Bernardi, G.9    Zona, C.10
  • 17
    • 0028933344 scopus 로고
    • Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS)
    • Dal Canto MC & Gurney ME (1995). Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 676, 25-40.
    • (1995) Brain Res , vol.676 , pp. 25-40
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 18
    • 34249075140 scopus 로고    scopus 로고
    • Alterations in intrinsic neuronal excitability during normal aging
    • Disterhoft JF & Oh MM (2007). Alterations in intrinsic neuronal excitability during normal aging. Aging cell 6, 327-336.
    • (2007) Aging cell , vol.6 , pp. 327-336
    • Disterhoft, J.F.1    Oh, M.M.2
  • 19
    • 77951615746 scopus 로고    scopus 로고
    • Evidence from computer simulations for alterations in the membrane biophysical properties and dendritic processing of synaptic inputs in mutant superoxide dismutase-1 motoneurons
    • Elbasiouny SM, Amendola J, Durand J & Heckman CJ (2010). Evidence from computer simulations for alterations in the membrane biophysical properties and dendritic processing of synaptic inputs in mutant superoxide dismutase-1 motoneurons. J Neurosci 30, 5544-5558.
    • (2010) J Neurosci , vol.30 , pp. 5544-5558
    • Elbasiouny, S.M.1    Amendola, J.2    Durand, J.3    Heckman, C.J.4
  • 20
    • 32344437345 scopus 로고    scopus 로고
    • Spontaneous network activity in the embryonic spinal cord regulates AMPAergic and GABAergic synaptic strength
    • Gonzalez-Islas C & Wenner P (2006). Spontaneous network activity in the embryonic spinal cord regulates AMPAergic and GABAergic synaptic strength. Neuron 49, 563-575.
    • (2006) Neuron , vol.49 , pp. 563-575
    • Gonzalez-Islas, C.1    Wenner, P.2
  • 21
    • 60849094474 scopus 로고    scopus 로고
    • Early detection of denervated muscle fibers in hindlimb muscles after sciatic nerve transection in wild type mice and in the G93A mouse model of amyotrophic lateral sclerosis
    • Gordon T, Ly V, Hegedus J & Tyreman N (2009). Early detection of denervated muscle fibers in hindlimb muscles after sciatic nerve transection in wild type mice and in the G93A mouse model of amyotrophic lateral sclerosis. Neurol Res 31, 28-42.
    • (2009) Neurol Res , vol.31 , pp. 28-42
    • Gordon, T.1    Ly, V.2    Hegedus, J.3    Tyreman, N.4
  • 22
    • 0030050727 scopus 로고    scopus 로고
    • Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
    • Gurney ME, Cutting FB, Zhai P, Doble A, Taylor CP, Andrus PK & Hall ED (1996). Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann Neurol 39, 147-157.
    • (1996) Ann Neurol , vol.39 , pp. 147-157
    • Gurney, M.E.1    Cutting, F.B.2    Zhai, P.3    Doble, A.4    Taylor, C.P.5    Andrus, P.K.6    Hall, E.D.7
  • 23
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
    • Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD et al (1994). Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 264, 1772-1775.
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1    Pu, H.2    Chiu, A.Y.3    Dal Canto, M.C.4    Polchow, C.Y.5    Alexander, D.D.6
  • 24
    • 0028365121 scopus 로고
    • Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole
    • Hebert T, Drapeau P, Pradier L & Dunn RJ (1994). Block of the rat brain IIA sodium channel alpha subunit by the neuroprotective drug riluzole. Mol Pharmacol 45, 1055-1060.
    • (1994) Mol Pharmacol , vol.45 , pp. 1055-1060
    • Hebert, T.1    Drapeau, P.2    Pradier, L.3    Dunn, R.J.4
  • 25
    • 43049143860 scopus 로고    scopus 로고
    • Persistent inward currents in spinal motoneurons and their influence on human motoneuron firing patterns
    • Heckman CJ, Johnson M, Mottram C & Schuster J (2008). Persistent inward currents in spinal motoneurons and their influence on human motoneuron firing patterns. Neuroscientist 14, 264-275.
    • (2008) Neuroscientist , vol.14 , pp. 264-275
    • Heckman, C.J.1    Johnson, M.2    Mottram, C.3    Schuster, J.4
  • 26
    • 35349025311 scopus 로고    scopus 로고
    • Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis
    • Hegedus J, Putman CT & Gordon T (2007). Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. Neurobiol Dis 28, 154-164.
    • (2007) Neurobiol Dis , vol.28 , pp. 154-164
    • Hegedus, J.1    Putman, C.T.2    Gordon, T.3
  • 27
    • 48949120504 scopus 로고    scopus 로고
    • Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis
    • Hegedus J, Putman CT, Tyreman N & Gordon T (2008). Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis. J Physiol 586, 3337-3351.
    • (2008) J Physiol , vol.586 , pp. 3337-3351
    • Hegedus, J.1    Putman, C.T.2    Tyreman, N.3    Gordon, T.4
  • 28
    • 0030886021 scopus 로고    scopus 로고
    • Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons
    • Huang CS, Song JH, Nagata K, Yeh JZ & Narahashi T (1997). Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons. J Pharmacol Exp Ther 282, 1280-1290.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1280-1290
    • Huang, C.S.1    Song, J.H.2    Nagata, K.3    Yeh, J.Z.4    Narahashi, T.5
  • 29
    • 0345303944 scopus 로고    scopus 로고
    • Key mechanisms for setting the input-output gain across the motoneuron pool
    • Hultborn H, Brownstone RB, Toth TI & Gossard JP (2004). Key mechanisms for setting the input-output gain across the motoneuron pool. Prog Brain Res 143, 77-95.
    • (2004) Prog Brain Res , vol.143 , pp. 77-95
    • Hultborn, H.1    Brownstone, R.B.2    Toth, T.I.3    Gossard, J.P.4
  • 30
    • 50449101429 scopus 로고    scopus 로고
    • Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
    • Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M & Cleveland DW (2008). Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death. Proc Natl Acad Sci U S A 105, 12599-12604.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 12599-12604
    • Ilieva, H.S.1    Yamanaka, K.2    Malkmus, S.3    Kakinohana, O.4    Yaksh, T.5    Marsala, M.6    Cleveland, D.W.7
  • 31
    • 72849120555 scopus 로고    scopus 로고
    • Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis
    • Jiang M, Schuster JE, Fu R, Siddique T & Heckman CJ (2009). Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis. J Neurosci 29, 15031-15038.
    • (2009) J Neurosci , vol.29 , pp. 15031-15038
    • Jiang, M.1    Schuster, J.E.2    Fu, R.3    Siddique, T.4    Heckman, C.J.5
  • 32
    • 0032821019 scopus 로고    scopus 로고
    • Development of L-type calcium channels and a nifedipine-sensitive motor activity in the postnatal mouse spinal cord
    • Jiang Z, Rempel J, Li J, Sawchuk MA, Carlin KP & Brownstone RM (1999). Development of L-type calcium channels and a nifedipine-sensitive motor activity in the postnatal mouse spinal cord. Eur J Neurosci 11, 3481-3487.
    • (1999) Eur J Neurosci , vol.11 , pp. 3481-3487
    • Jiang, Z.1    Rempel, J.2    Li, J.3    Sawchuk, M.A.4    Carlin, K.P.5    Brownstone, R.M.6
  • 33
    • 0032079517 scopus 로고    scopus 로고
    • Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
    • Kong J & Xu Z (1998). Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci 18, 3241-3250.
    • (1998) J Neurosci , vol.18 , pp. 3241-3250
    • Kong, J.1    Xu, Z.2
  • 34
    • 77954478713 scopus 로고    scopus 로고
    • Neurological channelopathies: new insights into disease mechanisms and ion channel function
    • Kullmann DM & Waxman SG (2010). Neurological channelopathies: new insights into disease mechanisms and ion channel function. J Physiol 588, 1823-1827.
    • (2010) J Physiol , vol.588 , pp. 1823-1827
    • Kullmann, D.M.1    Waxman, S.G.2
  • 36
    • 15844431408 scopus 로고    scopus 로고
    • + current and its effect on excitability in motoneurones cultured from mutant SOD1 mice
    • + current and its effect on excitability in motoneurones cultured from mutant SOD1 mice. J Physiol 563, 843-854.
    • (2005) J Physiol , vol.563 , pp. 843-854
    • Kuo, J.J.1    Siddique, T.2    Fu, R.3    Heckman, C.J.4
  • 38
    • 44649173763 scopus 로고    scopus 로고
    • 2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro
    • 2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro. Eur J Neurosci 27, 2501-2514.
    • (2008) Eur J Neurosci , vol.27 , pp. 2501-2514
    • Lamanauskas, N.1    Nistri, A.2
  • 39
    • 0021286962 scopus 로고
    • Activation patterns of embryonic chick hind limb muscles recorded in ovo and in an isolated spinal cord preparation
    • Landmesser LT & O'Donovan MJ (1984). Activation patterns of embryonic chick hind limb muscles recorded in ovo and in an isolated spinal cord preparation. J Physiol 347, 189-204.
    • (1984) J Physiol , vol.347 , pp. 189-204
    • Landmesser, L.T.1    O'Donovan, M.J.2
  • 40
    • 0034077807 scopus 로고    scopus 로고
    • Current and voltage clamp studies of the spike medium afterhyperpolarization of hypoglossal motoneurons in a rat brain stem slice preparation
    • Lape R & Nistri A (2000). Current and voltage clamp studies of the spike medium afterhyperpolarization of hypoglossal motoneurons in a rat brain stem slice preparation. J Neurophysiol 83, 2987-2995.
    • (2000) J Neurophysiol , vol.83 , pp. 2987-2995
    • Lape, R.1    Nistri, A.2
  • 41
    • 33846908702 scopus 로고    scopus 로고
    • Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury
    • Li X, Murray K, Harvey PJ, Ballou EW & Bennett DJ (2007). Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 97, 1236-1246.
    • (2007) J Neurophysiol , vol.97 , pp. 1236-1246
    • Li, X.1    Murray, K.2    Harvey, P.J.3    Ballou, E.W.4    Bennett, D.J.5
  • 42
    • 0041816000 scopus 로고    scopus 로고
    • Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats
    • Li Y & Bennett DJ (2003). Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats. J Neurophysiol 90, 857-869.
    • (2003) J Neurophysiol , vol.90 , pp. 857-869
    • Li, Y.1    Bennett, D.J.2
  • 43
    • 70349123549 scopus 로고    scopus 로고
    • Fast kinetics, high-frequency oscillations, and subprimary firing range in adult mouse spinal motoneurons
    • Manuel M, Iglesias C, Donnet M, Leroy F, Heckman CJ & Zytnicki D (2009). Fast kinetics, high-frequency oscillations, and subprimary firing range in adult mouse spinal motoneurons. J Neurosci 29, 11246-11256.
    • (2009) J Neurosci , vol.29 , pp. 11246-11256
    • Manuel, M.1    Iglesias, C.2    Donnet, M.3    Leroy, F.4    Heckman, C.J.5    Zytnicki, D.6
  • 44
    • 33745712893 scopus 로고    scopus 로고
    • Variability, compensation and homeostasis in neuron and network function
    • Marder E & Goaillard JM (2006). Variability, compensation and homeostasis in neuron and network function. Nat Rev Neurosci 7, 563-574.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 563-574
    • Marder, E.1    Goaillard, J.M.2
  • 45
    • 13844264524 scopus 로고    scopus 로고
    • Development of central pattern generating circuits
    • Marder E & Rehm KJ (2005). Development of central pattern generating circuits. Curr Opin Neurobiol 15, 86-93.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 86-93
    • Marder, E.1    Rehm, K.J.2
  • 46
    • 78149482855 scopus 로고    scopus 로고
    • Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: evidence for increased persistent inward currents
    • Meehan CF, Moldovan M, Marklund SL, Graffmo KS, Nielsen JB & Hultborn H (2010a). Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: evidence for increased persistent inward currents. Acta Physiol (Oxf) 200, 361-376.
    • (2010) Acta Physiol (Oxf) , vol.200 , pp. 361-376
    • Meehan, C.F.1    Moldovan, M.2    Marklund, S.L.3    Graffmo, K.S.4    Nielsen, J.B.5    Hultborn, H.6
  • 47
    • 77952978909 scopus 로고    scopus 로고
    • Intrinsic properties of mouse lumbar motoneurons revealed by intracellular recording in vivo
    • Meehan CF, Sukiasyan N, Zhang M, Nielsen JB & Hultborn H (2010b). Intrinsic properties of mouse lumbar motoneurons revealed by intracellular recording in vivo. J Neurophysiol 103, 2599-2610.
    • (2010) J Neurophysiol , vol.103 , pp. 2599-2610
    • Meehan, C.F.1    Sukiasyan, N.2    Zhang, M.3    Nielsen, J.B.4    Hultborn, H.5
  • 48
    • 0031898458 scopus 로고    scopus 로고
    • Strength-duration properties of sensory and motor axons in amyotrophic lateral sclerosis
    • Mogyoros I, Kiernan MC, Burke D & Bostock H (1998). Strength-duration properties of sensory and motor axons in amyotrophic lateral sclerosis. Brain 121, 851-859.
    • (1998) Brain , vol.121 , pp. 851-859
    • Mogyoros, I.1    Kiernan, M.C.2    Burke, D.3    Bostock, H.4
  • 49
    • 0032051750 scopus 로고    scopus 로고
    • Selective loss of α motoneurons innervating the medial gastrocnemius muscle in a mouse model of amyotrophic lateral sclerosis
    • Mohajeri MH, Figlewicz DA & Bohn MC (1998). Selective loss of α motoneurons innervating the medial gastrocnemius muscle in a mouse model of amyotrophic lateral sclerosis. Exp Neurol 150, 329-336.
    • (1998) Exp Neurol , vol.150 , pp. 329-336
    • Mohajeri, M.H.1    Figlewicz, D.A.2    Bohn, M.C.3
  • 50
    • 0029890685 scopus 로고    scopus 로고
    • The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
    • Mourelatos Z, Gonatas NK, Stieber A, Gurney ME & Dal Canto MC (1996). The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu, Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease. Proc Natl Acad Sci U S A 93, 5472-5477.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5472-5477
    • Mourelatos, Z.1    Gonatas, N.K.2    Stieber, A.3    Gurney, M.E.4    Dal Canto, M.C.5
  • 52
    • 72749112308 scopus 로고    scopus 로고
    • Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice
    • Pambo-Pambo A, Durand J & Gueritaud JP (2009). Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice. J Neurophysiol 102, 3627-3642.
    • (2009) J Neurophysiol , vol.102 , pp. 3627-3642
    • Pambo-Pambo, A.1    Durand, J.2    Gueritaud, J.P.3
  • 53
    • 0037289839 scopus 로고    scopus 로고
    • 2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current
    • 2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current. J Neurophysiol 89, 954-959.
    • (2003) J Neurophysiol , vol.89 , pp. 954-959
    • Perrier, J.F.1    Hounsgaard, J.2
  • 55
    • 58149527805 scopus 로고    scopus 로고
    • Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis
    • Pieri M, Carunchio I, Curcio L, Mercuri NB & Zona C (2009). Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis. Exp Neurol 215, 368-379.
    • (2009) Exp Neurol , vol.215 , pp. 368-379
    • Pieri, M.1    Carunchio, I.2    Curcio, L.3    Mercuri, N.B.4    Zona, C.5
  • 57
  • 58
    • 33344462702 scopus 로고    scopus 로고
    • Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
    • Pun S, Santos AF, Saxena S, Xu L & Caroni P (2006). Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF. Nat Neurosci 9, 408-419.
    • (2006) Nat Neurosci , vol.9 , pp. 408-419
    • Pun, S.1    Santos, A.F.2    Saxena, S.3    Xu, L.4    Caroni, P.5
  • 59
    • 0346156083 scopus 로고    scopus 로고
    • Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis
    • Rao SD & Weiss JH (2004). Excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis. Trends Neurosci 27, 17-23.
    • (2004) Trends Neurosci , vol.27 , pp. 17-23
    • Rao, S.D.1    Weiss, J.H.2
  • 61
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A et aly (1993). Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3    Figlewicz, D.A.4    Sapp, P.5    Hentati, A.6
  • 62
    • 0029847118 scopus 로고    scopus 로고
    • Excitotoxicity hypothesis
    • discussion S26.
    • Rothstein JD (1996). Excitotoxicity hypothesis. Neurology 47, S19-S25; discussion S26.
    • (1996) Neurology , vol.47
    • Rothstein, J.D.1
  • 63
    • 60849093466 scopus 로고    scopus 로고
    • Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
    • Rothstein JD (2009). Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann Neurol 65(Suppl 1), S3-S9.
    • (2009) Ann Neurol , vol.65 , Issue.SUPPL 1
    • Rothstein, J.D.1
  • 64
    • 18944369617 scopus 로고    scopus 로고
    • Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones
    • Rush AM, Dib-Hajj SD & Waxman SG (2005). Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones. J Physiol 564, 803-815.
    • (2005) J Physiol , vol.564 , pp. 803-815
    • Rush, A.M.1    Dib-Hajj, S.D.2    Waxman, S.G.3
  • 65
    • 67349164383 scopus 로고    scopus 로고
    • A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice
    • Saxena S, Cabuy E & Caroni P (2009). A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice. Nat Neurosci 12, 627-636.
    • (2009) Nat Neurosci , vol.12 , pp. 627-636
    • Saxena, S.1    Cabuy, E.2    Caroni, P.3
  • 66
    • 0018869558 scopus 로고
    • Properties of a persistent inward current in normal and TEA-injected motoneurons
    • Schwindt PC & Crill WE (1980). Properties of a persistent inward current in normal and TEA-injected motoneurons. J Neurophysiol 43, 1700-1724.
    • (1980) J Neurophysiol , vol.43 , pp. 1700-1724
    • Schwindt, P.C.1    Crill, W.E.2
  • 67
    • 0021809173 scopus 로고
    • Amyotrophic lateral sclerosis: Part 1. Clinical features, pathology, and ethical issues in management
    • Tandan R & Bradley WG (1985). Amyotrophic lateral sclerosis: Part 1. Clinical features, pathology, and ethical issues in management. Ann Neurol 18, 271-280.
    • (1985) Ann Neurol , vol.18 , pp. 271-280
    • Tandan, R.1    Bradley, W.G.2
  • 68
    • 23644456196 scopus 로고    scopus 로고
    • Systematic variation in effects of serotonin and norepinephrine on repetitive firing properties of ventral horn neurons
    • Theiss RD & Heckman CJ (2005). Systematic variation in effects of serotonin and norepinephrine on repetitive firing properties of ventral horn neurons. Neuroscience 134, 803-815.
    • (2005) Neuroscience , vol.134 , pp. 803-815
    • Theiss, R.D.1    Heckman, C.J.2
  • 69
    • 34147164057 scopus 로고    scopus 로고
    • Persistent inward currents in rat ventral horn neurones
    • Theiss RD, Kuo JJ & Heckman CJ (2007). Persistent inward currents in rat ventral horn neurones. J Physiol 580, 507-522.
    • (2007) J Physiol , vol.580 , pp. 507-522
    • Theiss, R.D.1    Kuo, J.J.2    Heckman, C.J.3
  • 70
    • 0017698204 scopus 로고
    • The numbers of limb motor neurons in the human lumbosacral cord throughout life
    • Tomlinson BE & Irving D (1977). The numbers of limb motor neurons in the human lumbosacral cord throughout life. J Neurol Sci 34, 213-219.
    • (1977) J Neurol Sci , vol.34 , pp. 213-219
    • Tomlinson, B.E.1    Irving, D.2
  • 71
    • 0033787252 scopus 로고    scopus 로고
    • Riluzole inhibits the persistent sodium current in mammalian CNS neurons
    • Urbani A & Belluzzi O (2000). Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur J Neurosci 12, 3567-3574.
    • (2000) Eur J Neurosci , vol.12 , pp. 3567-3574
    • Urbani, A.1    Belluzzi, O.2
  • 73
    • 33751229311 scopus 로고    scopus 로고
    • The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
    • Van Den Bosch L, Van Damme P, Bogaert E & Robberecht W (2006). The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis. Biochim Biophys Acta 1762, 1068-1082.
    • (2006) Biochim Biophys Acta , vol.1762 , pp. 1068-1082
    • Van Den Bosch, L.1    Van Damme, P.2    Bogaert, E.3    Robberecht, W.4
  • 74
    • 58149173426 scopus 로고    scopus 로고
    • Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis
    • van Zundert B, Peuscher MH, Hynynen M, Chen A, Neve RL, Brown RH Jr, Constantine-Paton M & Bellingham MC (2008). Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis. J Neurosci 28, 10864-10874.
    • (2008) J Neurosci , vol.28 , pp. 10864-10874
    • van Zundert, B.1    Peuscher, M.H.2    Hynynen, M.3    Chen, A.4    Neve, R.L.5    Brown Jr, R.H.6    Constantine-Paton, M.7    Bellingham, M.C.8
  • 75
    • 23944465642 scopus 로고    scopus 로고
    • 2+, mitochondria and selective motoneuron vulnerability: implications for ALS
    • 2+, mitochondria and selective motoneuron vulnerability: implications for ALS. Trends Neurosci 28, 494-500.
    • (2005) Trends Neurosci , vol.28 , pp. 494-500
    • von Lewinski, F.1    Keller, B.U.2
  • 76
    • 76549107634 scopus 로고    scopus 로고
    • Upregulation of persistent sodium conductances in familial ALS
    • Vucic S & Kiernan MC (2010). Upregulation of persistent sodium conductances in familial ALS. J Neurol Neurosurg Psychiatry 81, 222-227.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 222-227
    • Vucic, S.1    Kiernan, M.C.2
  • 77
    • 44949243975 scopus 로고    scopus 로고
    • Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis
    • Vucic S, Nicholson GA & Kiernan MC (2008). Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis. Brain 131, 1540-1550.
    • (2008) Brain , vol.131 , pp. 1540-1550
    • Vucic, S.1    Nicholson, G.A.2    Kiernan, M.C.3
  • 78
    • 75849150180 scopus 로고    scopus 로고
    • Epigenetic regulation of neuron-dependent induction of astroglial synaptic protein GLT1
    • Yang Y, Gozen O, Vidensky S, Robinson MB & Rothstein JD (2010). Epigenetic regulation of neuron-dependent induction of astroglial synaptic protein GLT1. Glia 58, 277-286.
    • (2010) Glia , vol.58 , pp. 277-286
    • Yang, Y.1    Gozen, O.2    Vidensky, S.3    Robinson, M.B.4    Rothstein, J.D.5
  • 80
    • 0032569619 scopus 로고    scopus 로고
    • Voltage-activated sodium currents in a cell line expressing a Cu,Zn superoxide dismutase typical of familial ALS
    • Zona C, Ferri A, Gabbianelli R, Mercuri NB, Bernardi G, Rotilio G & Carri MT (1998). Voltage-activated sodium currents in a cell line expressing a Cu, Zn superoxide dismutase typical of familial ALS. Neuroreport 9, 3515-3518.
    • (1998) Neuroreport , vol.9 , pp. 3515-3518
    • Zona, C.1    Ferri, A.2    Gabbianelli, R.3    Mercuri, N.B.4    Bernardi, G.5    Rotilio, G.6    Carri, M.T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.