-
1
-
-
78651410464
-
Beta-amyloid oligomers and prion protein: Fatal attraction?
-
Forloni G, Balducci C. beta-amyloid oligomers and prion protein: Fatal attraction? Prion 2011; 5:10-5.
-
(2011)
Prion
, vol.5
, pp. 10-15
-
-
Forloni, G.1
Balducci, C.2
-
2
-
-
33745893779
-
Alzheimer disease: Progress or profit?
-
DOI 10.1038/nm0706-780, PII NM0706780
-
Mount C, Downton C. Alzheimer disease: progress or profit? Nat Med 2006; 12:780-4. (Pubitemid 44050066)
-
(2006)
Nature Medicine
, vol.12
, Issue.7
, pp. 780-784
-
-
Mount, C.1
Downton, C.2
-
3
-
-
79952442060
-
Neuroprotective therapeutics for Alzheimer's disease: Progress and prospects
-
Palmer AM. Neuroprotective therapeutics for Alzheimer's disease: progress and prospects. Trends Pharmacol Sci 2011; 32:141-7.
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 141-147
-
-
Palmer, A.M.1
-
4
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ. Alzheimer's disease: genes, proteins and therapy. Physiol Rev 2001; 81:741-66. (Pubitemid 32267077)
-
(2001)
Physiological Reviews
, vol.81
, Issue.2
, pp. 741-766
-
-
Selkoe, D.J.1
-
5
-
-
61849157257
-
Alzheimer's disease
-
Burns A, Iliffe S. Alzheimer's disease. BMJ 2009; 338:158.
-
(2009)
BMJ
, vol.338
, pp. 158
-
-
Burns, A.1
Iliffe, S.2
-
6
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
DOI 10.1021/bi00069a001
-
Jarrett JT, Berger EP, Lansbury PT Jr. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993; 32:4693-7. (Pubitemid 23162022)
-
(1993)
Biochemistry
, vol.32
, Issue.18
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr., P.T.3
-
8
-
-
60349125886
-
Reassessing the amyloid cascade hypothesis of Alzheimer's disease
-
Pimplikar SW. Reassessing the amyloid cascade hypothesis of Alzheimer's disease. Int J Biochem Cell Biol 2009; 41:1261-8.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1261-1268
-
-
Pimplikar, S.W.1
-
10
-
-
0034682414
-
Neurotoxicity induces cleavage of p35 to p25 by calpain
-
DOI 10.1038/35012636
-
Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature 2000; 405:360-4. (Pubitemid 30337070)
-
(2000)
Nature
, vol.405
, Issue.6784
, pp. 360-364
-
-
Lee, M.-S.1
Kwon, Y.T.2
Li, M.3
Peng, J.4
Friedlander, R.M.5
Tsai, L.-H.6
-
11
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
Patrick GN, Zukerberg L, Nikolic M, de la Monte S, Dikkes P, Tsai LH. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature 1999; 402:615-22. (Pubitemid 129516324)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
De La, M.S.4
Dikkes, P.5
Tsai, L.-H.6
-
12
-
-
0031593593
-
Evolution of Alzheimer's disease related cortical lesions
-
Braak H, Braak E, Bohl J, Bratzke H. Evolution of Alzheimer's disease related cortical lesions. J Neural Transm Suppl 1998; 54:97-106. (Pubitemid 28539346)
-
(1998)
Journal of Neural Transmission, Supplement
, Issue.54
, pp. 97-106
-
-
Braak, H.1
Braak, E.2
Bohl, J.3
Bratzke, H.4
-
13
-
-
0038708285
-
Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease
-
Giannakopoulos P, Herrmann FR, Bussiere T, Bouras C, Kovari E, Perl DP, et al. Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology 2003; 60:1495-500. (Pubitemid 36559525)
-
(2003)
Neurology
, vol.60
, Issue.9
, pp. 1495-1500
-
-
Giannakopoulos, P.1
Herrmann, F.R.2
Bussiere, T.3
Bouras, C.4
Kovari, E.5
Perl, D.P.6
Morrison, J.H.7
Gold, G.8
Hof, P.R.9
-
14
-
-
40449135167
-
Beta-amyloid burden is not associated with rates of brain atrophy
-
DOI 10.1002/ana.21223
-
Josephs KA, Whitwell JL, Ahmed Z, Shiung MM, Weigand SD, Knopman DS, et al. Beta-amyloid burden is not associated with rates of brain atrophy. Ann Neurol 2008; 63:204-12. (Pubitemid 351355299)
-
(2008)
Annals of Neurology
, vol.63
, Issue.2
, pp. 204-212
-
-
Josephs, K.A.1
Whitwell, J.L.2
Ahmed, Z.3
Shiung, M.M.4
Weigand, S.D.5
Knopman, D.S.6
Boeve, B.F.7
Parisi, J.E.8
Petersen, R.C.9
Dickson, D.W.10
Jack Jr., C.R.11
-
15
-
-
0034093228
-
Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene. Expansion of the disease phenotype caused by tau gene mutations
-
Stanford PM, Halliday GM, Brooks WS, Kwok JB, Storey CE, Creasey H, et al. Progressive supranuclear palsy pathology caused by a novel silent mutation in exon 10 of the tau gene: expansion of the disease phenotype caused by tau gene mutations. Brain 2000; 123:880-93. (Pubitemid 30224185)
-
(2000)
Brain
, vol.123
, Issue.5
, pp. 880-893
-
-
Stanford, P.M.1
Halliday, G.M.2
Brooks, W.S.3
Kwok, J.B.J.4
Storey, C.E.5
Creasey, H.6
Morris, J.G.L.7
Fulham, M.J.8
Schofield, P.R.9
-
16
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991; 349:704-6. (Pubitemid 21912142)
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fldani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
17
-
-
0028170818
-
Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease
-
Selkoe DJ. Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease. Annu Rev Cell Biol 1994; 10:373-403. (Pubitemid 24372824)
-
(1994)
Annual Review of Cell Biology
, vol.10
, pp. 373-403
-
-
Selkoe, D.J.1
-
18
-
-
0026325645
-
Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion
-
Haass C, Hung AY, Selkoe DJ. Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion. J Neurosci 1991; 11:3783-93.
-
(1991)
J Neurosci
, vol.11
, pp. 3783-3793
-
-
Haass, C.1
Hung, A.Y.2
Selkoe, D.J.3
-
19
-
-
34447640166
-
The secreted beta-amyloid precursor protein ectodomain APPsalpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice
-
DOI 10.1523/JNEUROSCI.1026-07.2007
-
Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, et al. The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral and electrophysiological abnormalities of APP-deficient mice. J Neurosci 2007; 27:7817-26. (Pubitemid 47093823)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.29
, pp. 7817-7826
-
-
Ring, S.1
Weyer, S.W.2
Kilian, S.B.3
Waldron, E.4
Pietrzik, C.U.5
Filippov, M.A.6
Herms, J.7
Buchholz, C.8
Eckman, C.B.9
Korte, M.10
Wolfer, D.P.11
Muller, U.C.12
-
20
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimer's disease
-
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, et al. Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science 2010; 330:1774.
-
(2010)
Science
, vol.330
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
Morris, J.C.6
-
21
-
-
0025831751
-
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
-
Anderson JP, Esch FS, Keim PS, Sambamurti K, Lieberburg I, Robakis NK. Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells. Neurosci Lett 1991; 128:126-8.
-
(1991)
Neurosci Lett
, vol.128
, pp. 126-128
-
-
Anderson, J.P.1
Esch, F.S.2
Keim, P.S.3
Sambamurti, K.4
Lieberburg, I.5
Robakis, N.K.6
-
22
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids
-
Seubert P, Vigo-Pelfrey C, Esch F, Lee M, Dovey H, Davis D, et al. Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature 1992; 359:325-7.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
-
23
-
-
0028982454
-
Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease
-
Motter R, Vigo-Pelfrey C, Kholodenko D, Barbour R, Johnson-Wood K, Galasko D, et al. Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol 1995; 38:643-8.
-
(1995)
Ann Neurol
, vol.38
, pp. 643-648
-
-
Motter, R.1
Vigo-Pelfrey, C.2
Kholodenko, D.3
Barbour, R.4
Johnson-Wood, K.5
Galasko, D.6
-
24
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
DOI 10.1038/nm0896-864
-
Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, et al. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 1996; 2:864-70. (Pubitemid 26296755)
-
(1996)
Nature Medicine
, vol.2
, Issue.8
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
25
-
-
0034528425
-
Alpha-Secretase activity of the disintegrin metalloprotease ADAM 10: Influences of domain structure
-
Fahrenholz F, Gilbert S, Kojro E, Lammich S, Postina R. Alpha-secretase activity of the disintegrin metalloprotease ADAM 10. Influences of domain structure. Ann NY Acad Sci 2000; 920:215-22. (Pubitemid 32056572)
-
(2000)
Annals of the New York Academy of Sciences
, vol.920
, pp. 215-222
-
-
Fahrenholz, F.1
Gilbert, S.2
Kojro, E.3
Lammich, S.4
Postina, R.5
-
26
-
-
0037474447
-
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
-
DOI 10.1016/S0006-291X(02)02999-6
-
Asai M, Hattori C, Szabo B, Sasagawa N, Maruyama K, Tanuma S, et al. Putative function of ADAM9, ADAM10 and ADAM17 as APP alpha-secretase. Biochem Biophys Res Commun 2003; 301:231-5. (Pubitemid 36268873)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.301
, Issue.1
, pp. 231-235
-
-
Asai, M.1
Hattori, C.2
Szabo, B.3
Sasagawa, N.4
Maruyama, K.5
Tanuma, S.-I.6
Ishiura, S.7
-
27
-
-
33751409639
-
ADAM19 is tightly associated with constitutive Alzheimer's disease APP alpha-secretase in A172 cells
-
DOI 10.1016/j.bbrc.2006.10.181, PII S0006291X0602420X
-
Tanabe C, Hotoda N, Sasagawa N, Sehara-Fujisawa A, Maruyama K, Ishiura S. ADAM19 is tightly associated with constitutive Alzheimer's disease APP alpha-secretase in A172 cells. Biochem Biophys Res Commun 2007; 352:111-7. (Pubitemid 44821101)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.352
, Issue.1
, pp. 111-117
-
-
Tanabe, C.1
Hotoda, N.2
Sasagawa, N.3
Sehara-Fujisawa, A.4
Maruyama, K.5
Ishiura, S.6
-
28
-
-
30444440132
-
BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions
-
DOI 10.1523/JNEUROSCI.2766-05.2005
-
Laird FM, Cai H, Savonenko AV, Farah MH, He K, Melnikova T, et al. BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional and synaptic functions. J Neurosci 2005; 25:11693-709. (Pubitemid 43098462)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.50
, pp. 11693-11709
-
-
Laird, F.M.1
Cai, H.2
Savonenko, A.V.3
Farah, M.H.4
He, K.5
Melnikova, T.6
Wen, H.7
Chiang, H.-C.8
Xu, G.9
Koliatsos, V.E.10
Borchelt, D.R.11
Price, D.L.12
Lee, H.-K.13
Wong, P.C.14
-
29
-
-
57649245230
-
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis
-
O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, et al. Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron 2008; 60:988-1009.
-
(2008)
Neuron
, vol.60
, pp. 988-1009
-
-
O'Connor, T.1
Sadleir, K.R.2
Maus, E.3
Velliquette, R.A.4
Zhao, J.5
Cole, S.L.6
-
30
-
-
58549119790
-
The upregulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha
-
Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, et al. The upregulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem 2009; 108:1045-56.
-
(2009)
J Neurochem
, vol.108
, pp. 1045-1056
-
-
Guglielmotto, M.1
Aragno, M.2
Autelli, R.3
Giliberto, L.4
Novo, E.5
Colombatto, S.6
-
31
-
-
78650501836
-
Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor
-
Omar A, Jovanovic K, Da Costa Dias B, Gonsalves D, Moodley K, Caveney R, et al. Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor. Expert Opin Ther Pat 2011; 21:35-53.
-
(2011)
Expert Opin Ther Pat
, vol.21
, pp. 35-53
-
-
Omar, A.1
Jovanovic, K.2
Da Costa Dias, B.3
Gonsalves, D.4
Moodley, K.5
Caveney, R.6
-
32
-
-
77956630769
-
Interactions between PrP(c) and other ligands with the 37-kDa/67-kDa laminin receptor
-
Mbazima V, Da Costa Dias B, Omar A, Jovanovic K, Weiss SF. Interactions between PrP(c) and other ligands with the 37-kDa/67-kDa laminin receptor. Front Biosci 2010; 15:1150-63.
-
(2010)
Front Biosci
, vol.15
, pp. 1150-1163
-
-
Mbazima, V.1
Da Costa Dias, B.2
Omar, A.3
Jovanovic, K.4
Weiss, S.F.5
-
33
-
-
46749097518
-
Inhibition and Modulation of gamma-Secretase for Alzheimer's Disease
-
DOI 10.1016/j.nurt.2008.05.010, PII S1933721308000986
-
Wolfe MS. Inhibition and modulation of gamma-secretase for Alzheimer's disease. Neurotherapeutics 2008; 5:391-8. (Pubitemid 351952492)
-
(2008)
Neurotherapeutics
, vol.5
, Issue.3
, pp. 391-398
-
-
Wolfe, M.S.1
-
35
-
-
53749105377
-
Presenilins: Members of the gamma-secretase quartets, but part-time soloists too
-
(Bethesda)
-
Wakabayashi T, De Strooper B. Presenilins: members of the gamma-secretase quartets, but part-time soloists too. Physiology (Bethesda) 2008; 23:194-204.
-
(2008)
Physiology
, vol.23
, pp. 194-204
-
-
Wakabayashi, T.1
De Strooper, B.2
-
36
-
-
77953886784
-
Current status on Alzheimer disease molecular genetics: From past, to present, to future
-
Bettens K, Sleegers K, Van Broeckhoven C. Current status on Alzheimer disease molecular genetics: from past, to present, to future. Hum Mol Genet 2010; 19:4-11.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4-11
-
-
Bettens, K.1
Sleegers, K.2
Van Broeckhoven, C.3
-
37
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 1995; 269:973-7.
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
-
38
-
-
29444442794
-
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
-
DOI 10.1038/ng1718
-
Rovelet-Lecrux A, Hannequin D, Raux G, Le Meur N, Laquerriere A, Vital A, et al. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 2006; 38:24-6. (Pubitemid 43011878)
-
(2006)
Nature Genetics
, vol.38
, Issue.1
, pp. 24-26
-
-
Rovelet-Lecrux, A.1
Hannequin, D.2
Raux, G.3
Le, M.N.4
Laquerriere, A.5
Vital, A.6
Dumanchin, C.7
Feuillette, S.8
Brice, A.9
Vercelletto, M.10
Dubas, F.11
Frebourg, T.12
Campion, D.13
-
39
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
DOI 10.1016/S0166-2236(96)01030-2, PII S0166223696010302
-
Hardy J. Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci 1997; 20:154-9. (Pubitemid 27116286)
-
(1997)
Trends in Neurosciences
, vol.20
, Issue.4
, pp. 154-159
-
-
Hardy, J.1
-
40
-
-
0031938304
-
Presenilin mutations in Alzheimer's disease
-
DOI 10.1002/(SICI)1098-1004(1998)11:3<183::AID-HUMU1>3.0.CO;2-J
-
Cruts M, Van Broeckhoven C. Presenilin mutations in Alzheimer's disease. Hum Mutat 1998; 11:183-90. (Pubitemid 28132873)
-
(1998)
Human Mutation
, vol.11
, Issue.3
, pp. 183-190
-
-
Cruts, M.1
Van Broeckhoven, C.2
-
41
-
-
33745700370
-
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40
-
Kumar-Singh S, Theuns J, Van Broeck B, Pirici D, Vennekens K, Corsmit E, et al. Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40. Hum Mutat 2006; 27:686-95.
-
(2006)
Hum Mutat
, vol.27
, pp. 686-695
-
-
Kumar-Singh, S.1
Theuns, J.2
Van Broeck, B.3
Pirici, D.4
Vennekens, K.5
Corsmit, E.6
-
42
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter WJ, Saunders AM, Schmechel D, Pericak- Vance M, Enghild J, Salvesen GS, et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993; 90:1977-81. (Pubitemid 23069980)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.5
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
43
-
-
1842507631
-
Alzheimer's disease: One disorder, too many genes?
-
Bertram L, Tanzi RE. Alzheimer's disease: one disorder, too many genes? Hum Mol Genet 2004; 13:135-41.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 135-141
-
-
Bertram, L.1
Tanzi, R.E.2
-
44
-
-
32244435907
-
Role of genes and environments for explaining Alzheimer disease
-
DOI 10.1001/archpsyc.63.2.168
-
Gatz M, Reynolds CA, Fratiglioni L, Johansson B, Mortimer JA, Berg S, et al. Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry 2006; 63:168-74. (Pubitemid 43213878)
-
(2006)
Archives of General Psychiatry
, vol.63
, Issue.2
, pp. 168-174
-
-
Gatz, M.1
Reynolds, C.A.2
Fratiglioni, L.3
Johansson, B.4
Mortimer, J.A.5
Berg, S.6
Fiske, A.7
Pedersen, N.L.8
-
45
-
-
0037372585
-
PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease
-
DOI 10.1002/ana.10507
-
Dermaut B, Croes EA, Rademakers R, Van den Broeck M, Cruts M, Hofman A, et al. PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease. Ann Neurol 2003; 53:409-12. (Pubitemid 36258648)
-
(2003)
Annals of Neurology
, vol.53
, Issue.3
, pp. 409-412
-
-
Dermaut, B.1
Croes, E.A.2
Rademakers, R.3
Van Den, B.M.V.4
Cruts, M.5
Hofman, A.6
Van Duijn, C.M.7
Van Broeckhoven, C.8
-
46
-
-
3242778476
-
Prion protein codon 129 polymorphism and risk of Alzheimer disease
-
Riemenschneider M, Klopp N, Xiang W, Wagenpfeil S, Vollmert C, Muller U, et al. Prion protein codon 129 polymorphism and risk of Alzheimer disease. Neurology 2004; 63:364-6. (Pubitemid 38971146)
-
(2004)
Neurology
, vol.63
, Issue.2
, pp. 364-366
-
-
Riemenschneider, M.1
Klopp, N.2
Xiang, W.3
Wagenpfeil, S.4
Vollmert, C.5
Muller, U.6
Forstl, H.7
Illig, T.8
Kretzschmar, H.9
Kurz, A.10
-
47
-
-
0041816383
-
Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization
-
DOI 10.1074/jbc.M300825200
-
Bitan G, Vollers SS, Teplow DB. Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization. J Biol Chem 2003; 278:34882-9. (Pubitemid 37102247)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.37
, pp. 34882-34889
-
-
Bitan, G.1
Vollers, S.S.2
Teplow, D.B.3
-
48
-
-
33749832945
-
Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach
-
Teplow DB, Lazo ND, Bitan G, Bernstein S, Wyttenbach T, Bowers MT, et al. Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach. Acc Chem Res 2006; 39:635-45.
-
(2006)
Acc Chem Res
, vol.39
, pp. 635-645
-
-
Teplow, D.B.1
Lazo, N.D.2
Bitan, G.3
Bernstein, S.4
Wyttenbach, T.5
Bowers, M.T.6
-
49
-
-
33645505550
-
Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: A potent role for trimers
-
Townsend M, Shankar GM, Mehta T, Walsh DM, Selkoe DJ. Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers. J Physiol 2006; 572:477-92.
-
(2006)
J Physiol
, vol.572
, pp. 477-492
-
-
Townsend, M.1
Shankar, G.M.2
Mehta, T.3
Walsh, D.M.4
Selkoe, D.J.5
-
50
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 1991; 30:572-80.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
Butters, N.4
DeTeresa, R.5
Hill, R.6
-
51
-
-
41149109089
-
Amyloid plaque imaging in vivo: Current achievement and future prospects
-
Nordberg A. Amyloid plaque imaging in vivo: current achievement and future prospects. Eur J Nucl Med Mol Imaging 2008; 35:46-50.
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 46-50
-
-
Nordberg, A.1
-
52
-
-
38949208262
-
Plaque-bearing mice with reduced levels of oligomeric amyloid-beta assemblies have intact memory function
-
Lesne S, Kotilinek L, Ashe KH. Plaque-bearing mice with reduced levels of oligomeric amyloid-beta assemblies have intact memory function. Neuroscience 2008; 151:745-9.
-
(2008)
Neuroscience
, vol.151
, pp. 745-749
-
-
Lesne, S.1
Kotilinek, L.2
Ashe, K.H.3
-
53
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, Garcia-Munoz A, Shepardson NE, Smith I, et al. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 2008; 14:837-42.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
Garcia-Munoz, A.4
Shepardson, N.E.5
Smith, I.6
-
54
-
-
79251544549
-
Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: Implications for early detection and therapy
-
Marchesi VT. Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative-induced inflammation and dysregulated amyloid metabolism: implications for early detection and therapy. FASEB J 2011; 25:5-13.
-
(2011)
FASEB J
, vol.25
, pp. 5-13
-
-
Marchesi, V.T.1
-
55
-
-
75949114059
-
Alzheimer's disease as homeostatic responses to age-related myelin breakdown
-
Bartzokis G. Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging 2009.
-
(2009)
Neurobiol Aging
-
-
Bartzokis, G.1
-
56
-
-
77953658771
-
Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5
-
Renner M, Lacor PN, Velasco PT, Xu J, Contractor A, Klein WL, et al. Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5. Neuron 2010; 66:739-54.
-
(2010)
Neuron
, vol.66
, pp. 739-754
-
-
Renner, M.1
Lacor, P.N.2
Velasco, P.T.3
Xu, J.4
Contractor, A.5
Klein, W.L.6
-
57
-
-
0037135272
-
Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists
-
DOI 10.1016/S0306-4522(02)00132-X, PII S030645220200132X
-
Bi X, Gall CM, Zhou J, Lynch G. Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists. Neuroscience 2002; 112:827-40. (Pubitemid 34667047)
-
(2002)
Neuroscience
, vol.112
, Issue.4
, pp. 827-840
-
-
Bi, X.1
Gall, C.M.2
Zhou, J.3
Lynch, G.4
-
58
-
-
0026570528
-
Beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
-
Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992; 12:376-89.
-
(1992)
J Neurosci
, vol.12
, pp. 376-389
-
-
Mattson, M.P.1
Cheng, B.2
Davis, D.3
Bryant, K.4
Lieberburg, I.5
Rydel, R.E.6
-
59
-
-
78049290389
-
Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity
-
Stefani M. Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity. FEBS J 2010; 277:4602-13.
-
(2010)
FEBS J
, vol.277
, pp. 4602-4613
-
-
Stefani, M.1
-
60
-
-
77955701756
-
Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property
-
Sepulveda FJ, Parodi J, Peoples RW, Opazo C, Aguayo LG. Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property. PLoS One 2010; 5:11820.
-
(2010)
PLoS One
, vol.5
, pp. 11820
-
-
Sepulveda, F.J.1
Parodi, J.2
Peoples, R.W.3
Opazo, C.4
Aguayo, L.G.5
-
61
-
-
68049131387
-
Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers
-
Qiu L, Lewis A, Como J, Vaughn MW, Huang J, Somerharju P, et al. Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers. Biophys J 2009; 96:4299-307.
-
(2009)
Biophys J
, vol.96
, pp. 4299-4307
-
-
Qiu, L.1
Lewis, A.2
Como, J.3
Vaughn, M.W.4
Huang, J.5
Somerharju, P.6
-
62
-
-
55949104921
-
Membrane microdomain switching: A regulatory mechanism of amyloid precursor protein processing
-
Sakurai T, Kaneko K, Okuno M, Wada K, Kashiyama T, Shimizu H, et al. Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing. J Cell Biol 2008; 183:339-52.
-
(2008)
J Cell Biol
, vol.183
, pp. 339-352
-
-
Sakurai, T.1
Kaneko, K.2
Okuno, M.3
Wada, K.4
Kashiyama, T.5
Shimizu, H.6
-
63
-
-
1442351177
-
Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease
-
DOI 10.2174/1389203043486937
-
Verdier Y, Penke B. Binding sites of amyloid beta-peptide in cell plasma membrane and implications for Alzheimer's disease. Curr Protein Pept Sci 2004; 5:19-31. (Pubitemid 38279402)
-
(2004)
Current Protein and Peptide Science
, vol.5
, Issue.1
, pp. 19-31
-
-
Verdier, Y.1
Penke, B.2
-
64
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
-
DOI 10.1126/science.1141736
-
Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, et al. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 2007; 316:750-4. (Pubitemid 46717684)
-
(2007)
Science
, vol.316
, Issue.5825
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.-Q.8
Mucke, L.9
-
65
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
Ittner LM, Ke YD, Delerue F, Bi M, Gladbach A, van Eersel J, et al. Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models. Cell 2010; 142:387-97.
-
(2010)
Cell
, vol.142
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
Bi, M.4
Gladbach, A.5
Van Eersel, J.6
-
66
-
-
0025165018
-
Structure and function of laminin: Anatomy of a multidomain glycoprotein
-
Beck K, Hunter I, Engel J. Structure and function of laminin: anatomy of a multidomain glycoprotein. FASEB J 1990; 4:148-60.
-
(1990)
FASEB J
, vol.4
, pp. 148-160
-
-
Beck, K.1
Hunter, I.2
Engel, J.3
-
67
-
-
0027444745
-
beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin
-
DOI 10.1073/pnas.90.21.10150
-
Kibbey MC, Jucker M, Weeks BS, Neve RL, Van Nostrand WE, Kleinman HK. beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin. Proc Natl Acad Sci USA 1993; 90:10150-3. (Pubitemid 23328269)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.21
, pp. 10150-10153
-
-
Kibbey, M.C.1
Jucker, M.2
Weeks, B.S.3
Neve, R.L.4
Van Nostrand, W.E.5
Kleinman, H.K.6
-
69
-
-
0034332511
-
Laminin inhibition of beta-amyloid protein (Abeta) fibrillogenesis and identification of an Abeta binding site localized to the globular domain repeats on the laminin a chain
-
Castillo GM, Lukito W, Peskind E, Raskind M, Kirschner DA, Yee AG, et al. Laminin inhibition of beta-amyloid protein (Abeta) fibrillogenesis and identification of an Abeta binding site localized to the globular domain repeats on the laminin a chain. J Neurosci Res 2000; 62:451-62.
-
(2000)
J Neurosci Res
, vol.62
, pp. 451-462
-
-
Castillo, G.M.1
Lukito, W.2
Peskind, E.3
Raskind, M.4
Kirschner, D.A.5
Yee, A.G.6
-
70
-
-
77549087970
-
Prion protein: From physiology to cancer biology
-
Mehrpour M, Codogno P. Prion protein: From physiology to cancer biology. Cancer Lett 2010; 290:1-23.
-
(2010)
Cancer Lett
, vol.290
, pp. 1-23
-
-
Mehrpour, M.1
Codogno, P.2
-
72
-
-
26244466387
-
Bovine prion is endocytosed by human enterocytes via the 37 kDa/67 kDa laminin receptor
-
Morel E, Andrieu T, Casagrande F, Gauczynski S, Weiss S, Grassi J, et al. Bovine prion is endocytosed by human enterocytes via the 37 kDa/67 kDa laminin receptor. Am J Pathol 2005; 167:1033-42. (Pubitemid 41416255)
-
(2005)
American Journal of Pathology
, vol.167
, Issue.4
, pp. 1033-1042
-
-
Morel, E.1
Andrieu, T.2
Casagrande, F.3
Gauczynski, S.4
Weiss, S.5
Grassi, J.6
Rousset, M.7
Dormont, D.8
Chambaz, J.9
-
73
-
-
17944363361
-
The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein
-
DOI 10.1093/emboj/20.21.5863
-
Gauczynski S, Peyrin JM, Haik S, Leucht C, Hundt C, Rieger R, et al. The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein. EMBO J 2001; 20:5863-75. (Pubitemid 33049262)
-
(2001)
EMBO Journal
, vol.20
, Issue.21
, pp. 5863-5875
-
-
Gauczynski, S.1
Peyrin, J.-M.2
Haik, S.3
Leucht, C.4
Hundt, C.5
Rieger, R.6
Krasemann, S.7
Deslys, J.-P.8
Dormont, D.9
Lasmezas, C.I.10
Weiss, S.11
-
74
-
-
33748074456
-
The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes
-
DOI 10.1086/505914
-
Gauczynski S, Nikles D, El-Gogo S, Papy-Garcia D, Rey C, Alban S, et al. The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes. J Infect Dis 2006; 194:702-9. (Pubitemid 44297858)
-
(2006)
Journal of Infectious Diseases
, vol.194
, Issue.5
, pp. 702-709
-
-
Gauczynski, S.1
Nikles, D.2
El-Gogo, S.3
Papy-Garcia, D.4
Rey, C.5
Alban, S.6
Barritault, D.7
Lasmezas, C.I.8
Weiss, S.9
-
75
-
-
77956763891
-
Prion interaction with the 37-kDa/67-kDa laminin receptor on enterocytes as a cellular model for intestinal uptake of prions
-
Kolodziejczak D, Da Costa Dias B, Zuber C, Jovanovic K, Omar A, Beck J, et al. Prion interaction with the 37-kDa/67-kDa laminin receptor on enterocytes as a cellular model for intestinal uptake of prions. J Mol Biol 2010; 402:293-300.
-
(2010)
J Mol Biol
, vol.402
, pp. 293-300
-
-
Kolodziejczak, D.1
Da Costa Dias, B.2
Zuber, C.3
Jovanovic, K.4
Omar, A.5
Beck, J.6
-
76
-
-
78651389123
-
Alimentary prion infections: Touchdown in the intestine
-
Da Costa Dias B, Jovanovic K, Weiss SF. Alimentary prion infections: Touchdown in the intestine. Prion 2011; 5:6-9.
-
(2011)
Prion
, vol.5
, pp. 6-9
-
-
Da Costa Dias, B.1
Jovanovic, K.2
Weiss, S.F.3
-
77
-
-
0034916581
-
Prion diseases of humans and animals: Their causes and molecular basis
-
DOI 10.1146/annurev.neuro.24.1.519
-
Collinge J. Prion diseases of humans and animals: their causes and molecular basis. Annu Rev Neurosci 2001; 24:519-50. (Pubitemid 32695238)
-
(2001)
Annual Review of Neuroscience
, vol.24
, pp. 519-550
-
-
Collinge, J.1
-
78
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
-
Lauren J, Gimbel DA, Nygaard HB, Gilbert JW, Strittmatter SM. Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 2009; 457:1128-32.
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Lauren, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
79
-
-
77956197815
-
Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues
-
Chen S, Yadav SP, Surewicz WK. Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues. J Biol Chem 2010; 285:26377-83.
-
(2010)
J Biol Chem
, vol.285
, pp. 26377-26383
-
-
Chen, S.1
Yadav, S.P.2
Surewicz, W.K.3
-
80
-
-
34547400403
-
Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein
-
DOI 10.1073/pnas.0609621104
-
Parkin ET, Watt NT, Hussain I, Eckman EA, Eckman CB, Manson JC, et al. Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein. Proc Natl Acad Sci USA 2007; 104:11062-7. (Pubitemid 47175226)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.26
, pp. 11062-11067
-
-
Parkin, E.T.1
Watt, N.T.2
Hussain, I.3
Eckman, E.A.4
Eckman, C.B.5
Manson, J.C.6
Baybutt, H.N.7
Turner, A.J.8
Hooper, N.M.9
-
81
-
-
74249114011
-
Prion protein and Alzheimer disease
-
Kellett KA, Hooper NM. Prion protein and Alzheimer disease. Prion 2009; 3:190-4.
-
(2009)
Prion
, vol.3
, pp. 190-194
-
-
Kellett, K.A.1
Hooper, N.M.2
-
82
-
-
66249100230
-
p53-Dependent transcriptional control of cellular prion by presenilins
-
Vincent B, Sunyach C, Orzechowski HD, St. George-Hyslop P, Checler F. p53-Dependent transcriptional control of cellular prion by presenilins. J Neurosci 2009; 29:6752-60.
-
(2009)
J Neurosci
, vol.29
, pp. 6752-6760
-
-
Vincent, B.1
Sunyach, C.2
Orzechowski, H.D.3
St George-Hyslop, P.4
Checler, F.5
-
83
-
-
0037386086
-
The metallobiology of Alzheimer's disease
-
DOI 10.1016/S0166-2236(03)00067-5
-
Bush AI. The metallobiology of Alzheimer's disease. Trends Neurosci 2003; 26:207-14. (Pubitemid 36412003)
-
(2003)
Trends in Neurosciences
, vol.26
, Issue.4
, pp. 207-214
-
-
Bush, A.I.1
-
84
-
-
0035872476
-
Copper and prion disease
-
DOI 10.1016/S0361-9230(01)00453-1, PII S0361923001004531
-
Brown DR. Copper and prion disease. Brain Res Bull 2001; 55:165-73. (Pubitemid 32722156)
-
(2001)
Brain Research Bulletin
, vol.55
, Issue.2
, pp. 165-173
-
-
Brown, D.R.1
-
85
-
-
33746304427
-
Delineating common molecular mechanisms in Alzheimer's and prion diseases
-
DOI 10.1016/j.tibs.2006.06.006, PII S096800040600168X
-
Barnham KJ, Cappai R, Beyreuther K, Masters CL, Hill AF. Delineating common molecular mechanisms in Alzheimer's and prion diseases. Trends Biochem Sci 2006; 31:465-72. (Pubitemid 44108660)
-
(2006)
Trends in Biochemical Sciences
, vol.31
, Issue.8
, pp. 465-472
-
-
Barnham, K.J.1
Cappai, R.2
Beyreuther, K.3
Masters, C.L.4
Hill, A.F.5
-
86
-
-
0035851151
-
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein
-
Vincent B, Paitel E, Saftig P, Frobert Y, Hartmann D, De Strooper B, et al. The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J Biol Chem 2001; 276:37743-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 37743-37746
-
-
Vincent, B.1
Paitel, E.2
Saftig, P.3
Frobert, Y.4
Hartmann, D.5
De Strooper, B.6
-
87
-
-
28844433559
-
The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity
-
DOI 10.1074/jbc.M506069200
-
Cisse MA, Sunyach C, Lefranc-Jullien S, Postina R, Vincent B, Checler F. The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity. J Biol Chem 2005; 280:40624-31. (Pubitemid 41780553)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.49
, pp. 40624-40631
-
-
Cisse, M.A.1
Sunyach, C.2
Lefranc-Jullien, S.3
Postina, R.4
Vincent, B.5
Checler, F.6
-
88
-
-
0032820644
-
The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126
-
DOI 10.1046/j.1471-4159.1999.0731557.x
-
Jobling MF, Stewart LR, White AR, McLean C, Friedhuber A, Maher F, et al. The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126. J Neurochem 1999; 73:1557-65. (Pubitemid 29440157)
-
(1999)
Journal of Neurochemistry
, vol.73
, Issue.4
, pp. 1557-1565
-
-
Jobling, M.F.1
Stewart, L.R.2
White, A.R.3
McLean, C.4
Friedhuber, A.5
Maher, F.6
Beyreuther, K.7
Masters, C.L.8
Barrow, C.J.9
Collins, S.J.10
Cappai, R.11
-
89
-
-
0027367506
-
Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro
-
DOI 10.1073/pnas.90.20.9678
-
Tagliavini F, Prelli F, Verga L, Giaccone G, Sarma R, Gorevic P, et al. Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro. Proc Natl Acad Sci USA 1993; 90: 9678-82. (Pubitemid 23315849)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.20
, pp. 9678-9682
-
-
Tagliavini, F.1
Prelli, F.2
Verga, L.3
Giaccone, G.4
Sarma, R.5
Gorevic, P.6
Ghetti, B.7
Passerini, F.8
Ghibaudi, E.9
Forloni, G.10
Salmona, M.11
Bugiani, O.12
Frangione, B.13
-
90
-
-
0029997484
-
Role of microglia and host prion protein in neurotoxicity of a prion protein fragment
-
DOI 10.1038/380345a0
-
Brown DR, Schmidt B, Kretzschmar HA. Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature 1996; 380:345-7. (Pubitemid 26097115)
-
(1996)
Nature
, vol.380
, Issue.6572
, pp. 345-347
-
-
Brown, D.R.1
Schmidt, B.2
Kretzschmar, H.A.3
-
91
-
-
0033567401
-
Molecular determinants of the physicochemical properties of a critical prion protein region comprising residues 106-126
-
DOI 10.1042/0264-6021:3420207
-
Salmona M, Malesani P, De Gioia L, Gorla S, Bruschi M, Molinari A, et al. Molecular determinants of the physicochemical properties of a critical prion protein region comprising residues 106-126. Biochem J 1999; 342:207-14. (Pubitemid 29410867)
-
(1999)
Biochemical Journal
, vol.342
, Issue.1
, pp. 207-214
-
-
Salmona, M.1
Malesani, P.2
De Gioia, L.3
Gorla, S.4
Bruschi, M.5
Molinari, A.6
Della, V.F.7
Pedrotti, B.8
Marrari, M.A.9
Awan, T.10
Bugiani, O.11
Forloni, G.12
Tagliavini, F.13
-
92
-
-
0026628752
-
High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells
-
Wang KS, Kuhn RJ, Strauss EG, Ou S, Strauss JH. High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J Virol 1992; 66:4992-5001.
-
(1992)
J Virol
, vol.66
, pp. 4992-5001
-
-
Wang, K.S.1
Kuhn, R.J.2
Strauss, E.G.3
Ou, S.4
Strauss, J.H.5
-
93
-
-
7644219512
-
Serotype-specific entry of dengue virus into liver cells: Identification of the 37-kilodalton/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor
-
DOI 10.1128/JVI.78.22.12647-12656.2004
-
Thepparit C, Smith DR. Serotype-specific entry of dengue virus into liver cells: identification of the 37-kilodalton/67-kilodalton high-affinity laminin receptor as a dengue virus serotype 1 receptor. J Virol 2004; 78:12647-56. (Pubitemid 39458782)
-
(2004)
Journal of Virology
, vol.78
, Issue.22
, pp. 12647-12656
-
-
Thepparit, C.1
Smith, D.R.2
-
94
-
-
0032545335
-
LBP-p40 binds DNA tightly through associations with histones H2A, H2B, and H4
-
DOI 10.1006/bbrc.1998.9699
-
Kinoshita K, Kaneda Y, Sato M, Saeki Y, Wataya-Kaneda M, Hoffmann A. LBP-p40 binds DNA tightly through associations with histones H2A, H2B and H4. Biochem Biophys Res Commun 1998; 253:277-82. (Pubitemid 29026694)
-
(1998)
Biochemical and Biophysical Research Communications
, vol.253
, Issue.2
, pp. 277-282
-
-
Kinoshita, K.1
Kaneda, Y.2
Sato, M.3
Saeki, Y.4
Wataya-Kaneda, M.5
Hoffmann, A.6
Kaneda, Y.7
-
95
-
-
34250308322
-
Apoptosis: A Review of Programmed Cell Death
-
DOI 10.1080/01926230701320337, PII 779478428
-
Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007; 35:495-516. (Pubitemid 46911891)
-
(2007)
Toxicologic Pathology
, vol.35
, Issue.4
, pp. 495-516
-
-
Elmore, S.1
-
96
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner MO. The biochemistry of apoptosis. Nature 2000; 407:770-6.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
97
-
-
0037276437
-
The CD95(APO-1/Fas) DISC and beyond
-
DOI 10.1038/sj.cdd.4401186
-
Peter ME, Krammer PH. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ 2003; 10:26-35. (Pubitemid 36511830)
-
(2003)
Cell Death and Differentiation
, vol.10
, Issue.1
, pp. 26-35
-
-
Peter, M.E.1
Krammer, P.H.2
-
98
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
Miyashita T, Reed JC. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995; 80:293-9.
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
99
-
-
85047696563
-
Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death
-
DOI 10.1038/sj/onc/1205125
-
Henry H, Thomas A, Shen Y, White E. Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death. Oncogene 2002; 21:748-60. (Pubitemid 34146287)
-
(2002)
Oncogene
, vol.21
, Issue.5
, pp. 748-760
-
-
Henry, H.1
Thomas, A.2
Shen, Y.3
White, E.4
-
100
-
-
0037372013
-
Apoptosis and melanoma: Molecular mechanisms
-
DOI 10.1002/path.1300
-
Hussein MR, Haemel AK, Wood GS. Apoptosis and melanoma: molecular mechanisms. J Pathol 2003; 199:275-88. (Pubitemid 36266850)
-
(2003)
Journal of Pathology
, vol.199
, Issue.3
, pp. 275-288
-
-
Hussein, M.R.1
Haemel, A.K.2
Wood, G.S.3
-
101
-
-
0346873049
-
Anticancer therapy targeting the apoptotic pathway
-
DOI 10.1016/S1470-2045(03)01277-4
-
Hu W, Kavanagh JJ. Anticancer therapy targeting the apoptotic pathway. Lancet Oncol 2003; 4:721-9. (Pubitemid 37527207)
-
(2003)
Lancet Oncology
, vol.4
, Issue.12
, pp. 721-729
-
-
Hu, W.1
Kavanagh, J.J.2
-
102
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999; 397:441-6.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
-
103
-
-
0037067694
-
AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis
-
DOI 10.1074/jbc.M202285200
-
Wu M, Xu LG, Li X, Zhai Z, Shu HB. AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis. J Biol Chem 2002; 277:25617-23. (Pubitemid 34951879)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.28
, pp. 25617-25623
-
-
Wu, M.1
Xu, L.-G.2
Li, X.3
Zhai, Z.4
Shu, H.-B.5
-
104
-
-
0035674047
-
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
-
DOI 10.1038/sj.cdd.4400944
-
van Loo G, Schotte P, van Gurp M, Demol H, Hoorelbeke B, Gevaert K, et al. Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation. Cell Death Differ 2001; 8:1136-42. (Pubitemid 34048469)
-
(2001)
Cell Death and Differentiation
, vol.8
, Issue.12
, pp. 1136-1142
-
-
Van Loo, G.1
Schotte, P.2
Van Gurp, M.3
Demol, H.4
Hoorelbeke, B.5
Gevaert, K.6
Rodriguez, I.7
Ruiz-Carrillo, A.8
Vandekerckhove, J.9
Declercq, W.10
Beyaert, R.11
Vandenabeele, P.12
-
105
-
-
0027297138
-
Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF
-
DOI 10.1016/0006-8993(93)90295-X
-
Mattson MP, Tomaselli KJ, Rydel RE. Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF. Brain Res 1993; 621:35-49. (Pubitemid 23242158)
-
(1993)
Brain Research
, vol.621
, Issue.1
, pp. 35-49
-
-
Mattson, M.P.1
Tomaselli, K.J.2
Rydel, R.E.3
-
106
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
DOI 10.1016/0092-8674(94)90131-7
-
Behl C, Davis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994; 77:817-27. (Pubitemid 24187680)
-
(1994)
Cell
, vol.77
, Issue.6
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
107
-
-
0642375798
-
Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease
-
DOI 10.1016/S0006-2952(03)00534-3, PII S0006295203005343
-
Eckert A, Keil U, Marques CA, Bonert A, Frey C, Schussel K, et al. Mitochondrial dysfunction, apoptotic cell death and Alzheimer's disease. Biochem Pharmacol 2003; 66:1627-34. (Pubitemid 38373355)
-
(2003)
Biochemical Pharmacology
, vol.66
, Issue.8
, pp. 1627-1634
-
-
Eckert, A.1
Keil, U.2
Marques, C.A.3
Bonert, A.4
Frey, C.5
Schussel, K.6
Muller, W.E.7
-
108
-
-
0029787599
-
Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils
-
DOI 10.1038/382716a0
-
El Khoury J, Hickman SE, Thomas CA, Cao L, Silverstein SC, Loike JD. Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils. Nature 1996; 382:716-9. (Pubitemid 26282177)
-
(1996)
Nature
, vol.382
, Issue.6593
, pp. 716-719
-
-
El, K.J.1
Hickman, S.E.2
Thomas, C.A.3
Cao, L.4
Silverstein, S.C.5
Loike, J.D.6
-
109
-
-
0033579382
-
Microglial activation resulting from CD40-CD40l interaction after beta- amyloid stimulation
-
DOI 10.1126/science.286.5448.2352
-
Tan J, Town T, Paris D, Mori T, Suo Z, Crawford F, et al. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation. Science 1999; 286:2352-5. (Pubitemid 30016899)
-
(1999)
Science
, vol.286
, Issue.5448
, pp. 2352-2355
-
-
Tan, J.1
Town, T.2
Paris, D.3
Mori, T.4
Suo, Z.5
Crawford, F.6
Mattson, M.P.7
Flavell, R.A.8
Mullan, M.9
-
110
-
-
0035433962
-
Alzheimer's disease and Abeta toxicity: From top to bottom
-
DOI 10.1038/35086072
-
Small DH, Mok SS, Bornstein JC. Alzheimer's disease and Abeta toxicity: from top to bottom. Nat Rev Neurosci 2001; 2:595-8. (Pubitemid 33679833)
-
(2001)
Nature Reviews Neuroscience
, vol.2
, Issue.8
, pp. 595-598
-
-
Small, D.H.1
Mok, S.S.2
Bornstein, J.C.3
-
111
-
-
56349171792
-
siRNA-mediated silencing of the 37/67-kDa high affinity laminin receptor in Hep3B cells induces apoptosis
-
Susantad T, Smith DR. siRNA-mediated silencing of the 37/67-kDa high affinity laminin receptor in Hep3B cells induces apoptosis. Cell Mol Biol Lett 2008; 13:452-64.
-
(2008)
Cell Mol Biol Lett
, vol.13
, pp. 452-464
-
-
Susantad, T.1
Smith, D.R.2
-
113
-
-
77951896047
-
A kiss of a prion: New implications for oral transmissibility
-
Da Costa Dias B, Weiss SF. A kiss of a prion: new implications for oral transmissibility. J Infect Dis 2010; 201:1615-1616.
-
(2010)
J Infect Dis
, vol.201
, pp. 1615-1616
-
-
Da Costa Dias, B.1
Weiss, S.F.2
|